$344 Find Cheap Flights from Roanoke to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to South America departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Roanoke to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Rio de Janeiro
Rio de Janeiro1 stop$1,254
Guayaquil
Guayaquil2 stops$643
Rio de Janeiro
Rio de Janeiro1 stop$1,254
Guayaquil
Guayaquil2 stops$643

Book Cheap Roanoke to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to South America

Fri, May 8 - Thu, Aug 20
American Airlines Logo
8:00 pm - 1:31 pm
ROA
-
GYE
18h 31m
2 stops
American Airlines Logo
8:00 am - 10:23 pm
GYE
-
ROA
13h 23m
2 stops
$643American Airlines
Tue, May 5 - Thu, May 7
United Airlines Logo
6:00 am - 11:25 pm
ROA
-
UIO
18h 25m
2 stops
United Airlines Logo
12:35 am - 9:57 am
UIO
-
ROA
32h 22m
2 stops
$718United Airlines
Tue, May 5 - Thu, May 7
United Airlines Logo
10:34 am - 11:25 pm
ROA
-
UIO
13h 51m
2 stops
United Airlines Logo
12:35 am - 11:44 pm
UIO
-
ROA
22h 09m
2 stops
$738United Airlines
Tue, May 5 - Fri, May 8
LATAM Airlines Logo
6:00 am - 6:59 pm
ROA
-
UIO
13h 59m
1 stop
LATAM Airlines Logo
7:06 am - 10:30 am
UIO
-
ROA
26h 24m
2 stops
$743LATAM Airlines
Tue, May 5 - Fri, May 8
LATAM Airlines Logo
6:00 am - 6:59 pm
ROA
-
UIO
13h 59m
1 stop
LATAM Airlines Logo
7:06 am - 12:34 am
UIO
-
ROA
16h 28m
2 stops
$780LATAM Airlines
Wed, Mar 18 - Sun, Mar 22
Delta Logo
6:00 am - 7:20 am
ROA
-
GIG
24h 20m
1 stop
Delta Logo
7:15 am - 12:04 am
GIG
-
ROA
41h 49m
2 stops
$1,420Delta
Wed, Mar 18 - Sun, Mar 22
Delta Logo
6:00 am - 7:20 am
ROA
-
GIG
24h 20m
1 stop
Delta Logo
9:30 pm - 12:04 am
GIG
-
ROA
27h 34m
1 stop
$1,480Delta
Fri, Apr 17 - Fri, Apr 24
Avianca Logo
7:59 pm - 11:00 am
ROA
-
GIG
38h 01m
3 stops
Avianca Logo
4:40 pm - 7:10 pm
GIG
-
ROA
27h 30m
2 stops
$1,584Avianca
Fri, Apr 17 - Fri, Apr 24
Multiple Airlines Logo
2:55 pm - 8:15 pm
ROA
-
GIG
28h 20m
3 stops
Multiple Airlines Logo
4:55 pm - 2:13 pm
GIG
-
ROA
22h 18m
3 stops
$2,326Multiple Airlines
Fri, Apr 17 - Fri, Apr 24
Multiple Airlines Logo
10:34 am - 8:15 pm
ROA
-
SDU
32h 41m
3 stops
Multiple Airlines Logo
1:50 pm - 2:13 pm
SDU
-
ROA
25h 23m
3 stops
$2,518Multiple Airlines
Booking Insights

KAYAK's insights & trends for Roanoke to South America flights

Get data-powered insights and trends into flights from Roanoke to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Roanoke to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Roanoke to South America were found on American Airlines ($643) and United Airlines ($718).

Good to know

Low seasonJuly
Cheapest flight$344
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly with an average 7% increase in price.
Flight from Roanoke to Santiago

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Roanoke to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Roanoke to South America

 
Need help choosing which airline to fly with from Roanoke to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8258 reviews
8.1Boarding
8.5Crew
7.2Food
7.9Comfort
7.8Entertainment
Airline reviews

The whole experience was excellent. As it most often is with Delta

10.0 ExcellentRay, Mar 2026
LGA - MCO
Read more Delta reviews

The whole experience was excellent. As it most often is with Delta

Cabin was not pressurized properly. Several passengers had respiratory difficulties.

I was happy that I was able to get a last minute flight but unfortunately my seat was a middle seat. Even with Delta Comfort I wasn't comfortable

There’s not much to say about a one hour flight. This is a connection from LA to RNO that I missed the previous night due to a mechanical check delay on my originating flight from JFK to LAX. The short flight itself was fine. Instructions from the pilot and crew were per usual. The coffee was barely lukewarm, which possibly was purposeful so we would down it quickly. Bags were already on carousel upon reaching baggage claim, which was excellent.

Flight was warm for first few hours and quite rough

Seat was extremely hard which made even a short 1 hour 20 minute flight fairly uncomfortable.

Everything was good except wifi and a leaking drink chiller. The floor was all wet and my bag was soaked. Did not notice until debarking. Have not heard back from Delta. Even though this was leg one of an international flight in first class, they denied access to their Sky Club - very disappointing!

The staff was fine. The plane was extremely tight, and I paid for the wifi and it did not work at all. I was actually going to ask for a refund.

two hour delay and the Delta representative on the PA system was unable to understand

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

Nothing I like, I missed this connection b/c of an earlier flight delay. I had to stay one more night and I paid out my own pocket. LATAM failed to send me to a safe and decent hotel.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

On board crew was very good. Crew was friendly, snacks were good, especially the chips. Seats seemed a bit cramped. Boarding seemed unorganized, as we were instructed to get to the gate an hour early and then just stood around until boarding.

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor, the airline was not able to help me move flights.

Flight pulled out on time but sat on runway for 30 mins. It was extremely cold in the aircraft despite wearing a winter coat. Surprisingly they had a vegetarian meal but could have some better snack choices for a 8 hour flight.

We had a male flight attendant who was super attentive and wonderful! Very professional. I have both gluten and dairy intolerance, and was only able to get a gluten free part, and not the dairy free part of the meal. Easy to order ahead of time and I appreciate being able to do that.

Snow delayed boarding several times, which I understand happens. Issue I had was that after we did board, pilot told us we were going to roll out to be de-iced, then on our way. We were de-iced once, taxied to the tarmac and then stopped. Sat for another 30 minutes or so, the another de-icing. Then we rolled out to a parking spot, only to sit for another hour due to a traffic stop in DCA, which I'm confident they knew would happen before we boarded. Pilot gave no updates other than we had to hold, attendants did speak to the crew, but when asked, said the pilot would be updating us. We on the ground in the plane waiting for over 2 hours. They did communicate that bathrooms would be open, but no other news until we left. Would have been better to be up front about status.

Good crew and flight was on time. It’s a small plane with limited overhead luggage space. They said the overhead space was full and I had to check my bag. There was still space when I got on. Waiting for my checked luggage added 30 minutes to my trip. Not the end of the world but also not great.

My seat was assigned last row behind restrooms No legroom’s I’m very Pettit Still was not comfortable Food choice was excellent

Delayed initially because they couldn’t print the flight details. Poor instruction on delay. When I got on the plane the flight attendant argued with me about whether my carry on would fit (it did, although she didn’t acknowledge that). No greeting (other than arguing with me) getting on or off the plane.

Overall good. The pilots and flight attendants are excellent! The equipment was the issue on my First flight as they had to wait for a part to be installed. So the take off was at least 30 minutes later.

The worst Airline ever. They centered my second flight and leave me in NY. They don’t have any representatives at the airport and they don’t respond to calls. Basically I got stuck. I will never purchase through there again.

It was an older plane. First Class was not especially roomy or comfortable. It was a short flight so there were no meal but they did offer mixed nuts which used to be normal but now is rare. Crew member was very polite and professional.

The chicken wrap was tiny ($13 for what looked like a 1/3 of a normal wrap?) and disgusting.

Everything you need to know for your flight to South America

Information on your arrival and departure airports