$678 Find Cheap Flights from Roanoke to South America

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to South America departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Roanoke to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Rio de Janeiro
Rio de Janeiro2 stops$1,129
Santiago
Santiago2 stops$714
Rio de Janeiro
Rio de Janeiro2 stops$1,129
Santiago
Santiago2 stops$714

Book Cheap Roanoke to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to South America

Sat, Jan 31 - Tue, Feb 3
United Airlines Logo
5:39 pm - 12:30 am
ROA
-
UIO
30h 51m2 stops
United Airlines Logo
1:35 am - 2:46 pm
UIO
-
ROA
13h 11m2 stops
$664United Airlines
Sat, Jan 31 - Tue, Feb 3
United Airlines Logo
5:39 pm - 12:30 am
ROA
-
UIO
30h 51m2 stops
United Airlines Logo
1:35 am - 2:46 pm
UIO
-
ROA
13h 11m2 stops
$678United Airlines
Thu, Feb 5 - Mon, Feb 9
LATAM Airlines Logo
6:00 am - 2:20 pm
ROA
-
SCL
30h 20m2 stops
LATAM Airlines Logo
11:10 pm - 7:19 pm
SCL
-
ROA
22h 09m1 stop
$714LATAM Airlines
Thu, Feb 5 - Mon, Feb 9
LATAM Airlines Logo
6:00 am - 2:20 pm
ROA
-
SCL
30h 20m2 stops
LATAM Airlines Logo
7:15 am - 10:39 am
SCL
-
ROA
29h 24m3 stops
$719LATAM Airlines
Fri, Jan 23 - Sat, Jan 24
United Airlines Logo
6:45 am - 12:30 am
ROA
-
UIO
17h 45m2 stops
United Airlines Logo
1:35 am - 12:05 pm
UIO
-
ROA
34h 30m2 stops
$729United Airlines
Tue, Jan 13 - Tue, Jan 20
LATAM Airlines Logo
11:24 am - 6:10 am
ROA
-
SCL
16h 46m1 stop
LATAM Airlines Logo
9:30 pm - 10:39 am
SCL
-
ROA
15h 09m1 stop
$734LATAM Airlines
Tue, Jan 13 - Tue, Jan 20
LATAM Airlines Logo
11:24 am - 2:05 pm
ROA
-
SCL
24h 41m2 stops
LATAM Airlines Logo
11:10 pm - 7:19 pm
SCL
-
ROA
22h 09m1 stop
$739LATAM Airlines
Fri, Jan 23 - Sun, Jan 25
Delta Logo
7:05 am - 5:17 am
ROA
-
UIO
22h 12m2 stops
Delta Logo
11:45 pm - 10:39 am
UIO
-
ROA
10h 54m1 stop
$781Delta
Fri, Jan 23 - Sun, Jan 25
Delta Logo
7:59 pm - 9:35 pm
ROA
-
UIO
25h 36m1 stop
Delta Logo
11:45 pm - 3:07 pm
UIO
-
ROA
15h 22m1 stop
$782Delta
Sun, Jan 18 - Sun, Feb 1
Delta Logo
11:24 am - 8:20 am
ROA
-
GIG
18h 56m1 stop
Delta Logo
9:30 pm - 10:39 am
GIG
-
ROA
15h 09m1 stop
$1,220Delta
Booking Insights

KAYAK's insights & trends for Roanoke to South America flights

Get data-powered insights and trends into flights from Roanoke to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Roanoke and South America?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Roanoke to South America.

There is just one airline that flies from Roanoke to South America direct and that is Delta. The best round-trip deal found from Delta for the route is to Lima (LIM) and costs $746.

Which airlines provide the cheapest flights from Roanoke to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Roanoke to South America were found on United Airlines ($664) and LATAM Airlines ($714).

Good to know

Low seasonJuly
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly with an average 17% increase in price.

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Roanoke to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally at night, when round-trip flights cost $473 on average. On average, there is no price difference when choosing to fly in the morning or the evening on this flight route. The most expensive time of day to fly to South America is generally in the evening, which is peak travel time and where the average cost of a ticket is $733.

Reviews of the top airlines flying from Roanoke to South America

 
Need help choosing which airline to fly with from Roanoke to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8010 reviews
7.9Comfort
8.5Crew
7.9Entertainment
7.3Food
8.1Boarding
Airline reviews

None of the airplane features were available during the flight.

4.0 OkayAnonymous, Dec 2025
JFK - SDQ
Read more Delta reviews

None of the airplane features were available during the flight.

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

Lady Pilot was perfect in every way wheels up to wheels down communication, professionalism, excellent on time departure and on time arrival, excellent communication! Fantastic job with Superb attitude!!

The food is terrible. The staff is wonderful. Comfort is good.

Left on time, a bit delayed due to headwinds most of the trip.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Getting to the flight was arduous and lengthy. The flight itself was good but the food option wasn’t a good selection. I need to do a Kosher option on my return. Flight crew were nice

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Gate was overcrowded. Gate agents performed very well. Flight crew was top notch! Efficient & professional & courteous. Both meals not thermalized well. Dinner main dish was actually cold in the center. Almost inedible. Breakfast sandwich was lukewarm.

The boarding was as always, the crew tried their best but not enough. The food was a disaster I had dietary restrictions that were half met because the company did not loaded the food for the flight. The entertainment screen was fine but content was not and also they removed the free messaging option from the flight and they charged 30 dollars for that crappy bandwidth. This flight is not worth the cost and the company is going down on quality.

Not comparable to Qatar Airways services on flights to Doha. Flight attendants provided basic services; I was never recognized by name or as an Executive Platinum member. Restrooms were not kept clean during the flight.

Awful. They won’t help me with anything. I booked on American but they abdicated to Iberia. The ticket was overpriced. Everything negative

it was fine, decent flight... dont get food besides cookies or pretzels so not sure why you ask about food. same for entertainment..

I got sick nothing contagious but distressing and the care I received by Kayla? Keighly the flight attendant will be memorable for ever. Thank You

I got sick nothing contagious but distressing enough and the care I received on the flight was astounding.

Waaay too small plane. They also need to up the size of the overhead bins. I would love to keep me 3k with of camera equipment in my hard case baggahe instead of it being thrown into the belly of the plane

Attendants were pleasant and the flight was smooth and relaxed.

A little late at the start but all worked out well.

Everything you need to know for your flight to South America

Information on your arrival and departure airports