$423 Find Cheap Flights from Roanoke to South America

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to South America departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Roanoke to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Rio de Janeiro
Rio de Janeiro2 stops$1,491
Guayaquil
Guayaquil2 stops$526
Rio de Janeiro
Rio de Janeiro2 stops$1,491
Guayaquil
Guayaquil2 stops$526

Book Cheap Roanoke to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to South America

Thu, Mar 5 - Mon, Mar 16
American Airlines Logo
8:00 pm - 2:30 pm
ROA
-
GYE
18h 30m
2 stops
American Airlines Logo
2:30 pm - 11:34 am
GYE
-
ROA
20h 04m
2 stops
$526American Airlines
Thu, Mar 5 - Mon, Mar 16
American Airlines Logo
8:00 pm - 2:30 pm
ROA
-
GYE
18h 30m
2 stops
American Airlines Logo
2:30 pm - 2:25 pm
GYE
-
ROA
22h 55m
2 stops
$539American Airlines
Wed, Apr 22 - Mon, May 4
United Airlines Logo
5:40 pm - 11:25 pm
ROA
-
UIO
30h 45m
2 stops
United Airlines Logo
7:25 am - 10:16 am
UIO
-
ROA
25h 51m
2 stops
$590United Airlines
Wed, Apr 22 - Fri, May 1
United Airlines Logo
5:40 pm - 11:25 pm
ROA
-
UIO
30h 45m
2 stops
United Airlines Logo
12:35 am - 7:10 pm
UIO
-
ROA
17h 35m
2 stops
$600United Airlines
Mon, Apr 27 - Mon, May 4
United Airlines Logo
7:59 pm - 11:25 pm
ROA
-
UIO
28h 26m
2 stops
United Airlines Logo
12:35 am - 11:44 pm
UIO
-
ROA
22h 09m
2 stops
$606United Airlines
Fri, Apr 24 - Fri, May 1
United Airlines Logo
7:59 pm - 11:25 pm
ROA
-
UIO
28h 26m
2 stops
United Airlines Logo
12:35 am - 11:44 pm
UIO
-
ROA
22h 09m
2 stops
$610United Airlines
Thu, Apr 30 - Wed, May 13
United Airlines Logo
7:59 pm - 11:25 pm
ROA
-
UIO
28h 26m
2 stops
United Airlines Logo
12:35 am - 9:57 am
UIO
-
ROA
32h 22m
2 stops
$616United Airlines
Thu, Apr 23 - Thu, Apr 30
United Airlines Logo
6:45 am - 11:25 pm
ROA
-
UIO
17h 40m
2 stops
United Airlines Logo
12:35 am - 10:16 am
UIO
-
ROA
32h 41m
2 stops
$617United Airlines
Fri, Apr 24 - Thu, Apr 30
United Airlines Logo
7:59 pm - 11:25 pm
ROA
-
UIO
28h 26m
2 stops
United Airlines Logo
12:35 am - 9:57 am
UIO
-
ROA
32h 22m
2 stops
$627United Airlines
Sun, May 3 - Sun, May 17
United Airlines Logo
7:59 pm - 11:25 pm
ROA
-
UIO
28h 26m
2 stops
United Airlines Logo
7:25 am - 9:57 am
UIO
-
ROA
25h 32m
2 stops
$655United Airlines
Booking Insights

KAYAK's insights & trends for Roanoke to South America flights

Get data-powered insights and trends into flights from Roanoke to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Roanoke to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Roanoke to South America were found on American Airlines ($423) and United Airlines ($590).

Good to know

Low seasonJuly
Cheapest flight$526
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly with an average 7% increase in price.
Flight from Roanoke to Guayaquil

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Roanoke to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Roanoke to South America

 
Need help choosing which airline to fly with from Roanoke to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8162 reviews
7.8Entertainment
8.1Boarding
7.9Comfort
8.5Crew
7.2Food
Airline reviews

It was delayed but other than that it was great.

6.0 GoodJulian, Feb 2026
SEA - LAS
Read more Delta reviews

It was delayed but other than that it was great.

Got on the plane and sat there for an hour before departure.

Second flight in a row where the entertainment system is broken. 5 hour long flight with no entertainment and flight attendants did not seem interested in resolving the matter. Very shocked to be treated this poorly considering I paid for a first class experience and have Diamond Medallion status.

They double booked seats, the gate staff changed my ticket as I was boarding she went over to the computer and changed it without telling me. She messed up an entire three row section for me and others. Other travelers were outraged but the gate staff were so rude, so condescending saying it wasn't their problem to solve. I would rate this a zero if I could. Will not fly Delta again I'll stick with United and American.

It was nt delta. It was aeromexo. Service was awful. They served a very small drink and NO snack for a 3hr and 35min flight. Then for the first 30 min of the flight is was talk and talk over head interruption the movie/ show i picked to watch.

Comfort seating was on the tight side. Maybe it was a smaller plane(?)

I was given middle seat on this flight and prior Boston to Seoul flight That is a problem for long flights, Kayak system did not give me a change to select my seats and assigned me middle seats regardless of my elevated status in Delta. This needs immediate attention.

I didn't take this flight. I changed the flight. Why am I getting surveys and notifications on flights that I change. Seems like a defect with Kayak.

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

Timing, quality of service, promptness and courtesy of the staff

Apart of Sky miles delta. And they go everywhere in Brazil

On board crew was very good. Crew was friendly, snacks were good, especially the chips. Seats seemed a bit cramped. Boarding seemed unorganized, as we were instructed to get to the gate an hour early and then just stood around until boarding.

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor, the airline was not able to help me move flights.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

the plane was so hot!! the air-conditioning was barely blowing. The flight was delayed, and we had to sit on the hot plane before take off for an extended amount of time, waiting on international passengers. Would not have been so bad if it was not so hot. They said it would get better after take off, but it did not.

They are always late and seats was also not having working charger

We flew in first class. The crew did not offer drinks before the flight took off, but they treated us well during the flight. The food was excellent. There was actually too much food served, but it was nice to have all the options.

did not have enough meal for first class passengers so offer us snack

Arrived 40 min early which was great - sat in runway for 35 min so no gain. Then waited for luggage 45 min. They need to staff accordingly knowing its one of the busiest week in Phx

Broke my luggage and I can't get a resolution yet.

My flight got rerouted due to crew rest. I was sent to Dallas customer service was not very polite. Was given a $40 room voucher for Motel 6 and $12 to eat with. It delayed me by a day. Where if I would have just stuck with my original flight Arizona was delayed to Cleveland and I could have made it home. They put me on a 9:00 flight out of Dallas to Cleveland without my knowledge or consent. When originally I was told it would be 8:45 a.m. on February 1st. I told them I could not take the 9:00 flight because I did not have anybody to pick me up from the airport at that time. I'm extremely disappointed in how I was treated. And I will not fly American Airlines again.

I am very appreciative of the help provided to me by Dennis and Whitney. I had lost my phone at EWR airport and they were very kind in assisting me. This included advice on how to file a report and also helping me connect with family. The pilot was also great about keeping passengers updated on the flight progress with regular communications over the system.

Awful. Original flight was delayed 5 hours. Had to to take a connecting flight instead of direct. Had a 4 hour layover. I missed all of my morning meetings getting in 5 hours later than I was supposed to and had to change to take a later flight the next day to get them back in which cia time another $150.

Old equipment, needs upgrade and seat comfort. Internet didn't work 75% or the time.

Everything you need to know for your flight to South America

Information on your arrival and departure airports