$634 Find Cheap Flights from Roanoke to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to South America departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Roanoke to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to South America

Tue, Aug 11 - Thu, Aug 27
American Airlines Logo
6:00 am - 8:58 pm
ROA
-
UIO
15h 58m
2 stops
American Airlines Logo
11:40 pm - 2:25 pm
UIO
-
ROA
13h 45m
2 stops
$634American Airlines
Tue, Aug 11 - Wed, Aug 26
United Airlines Logo
7:00 am - 11:25 pm
ROA
-
UIO
17h 25m
2 stops
United Airlines Logo
12:35 am - 10:11 am
UIO
-
ROA
32h 36m
2 stops
$673United Airlines
Tue, May 5 - Thu, May 7
United Airlines Logo
7:59 pm - 11:25 pm
ROA
-
UIO
28h 26m
2 stops
United Airlines Logo
12:35 am - 11:44 pm
UIO
-
ROA
22h 09m
2 stops
$716United Airlines
Tue, May 5 - Thu, May 7
United Airlines Logo
6:00 am - 11:25 pm
ROA
-
UIO
18h 25m
2 stops
United Airlines Logo
12:35 am - 11:44 pm
UIO
-
ROA
22h 09m
2 stops
$718United Airlines
Tue, May 5 - Fri, May 8
LATAM Airlines Logo
6:00 am - 6:59 pm
ROA
-
UIO
13h 59m
1 stop
LATAM Airlines Logo
7:06 am - 10:30 am
UIO
-
ROA
26h 24m
2 stops
$752LATAM Airlines
Tue, May 5 - Fri, May 8
LATAM Airlines Logo
6:00 am - 6:59 pm
ROA
-
UIO
13h 59m
1 stop
LATAM Airlines Logo
7:06 am - 12:34 am
UIO
-
ROA
16h 28m
2 stops
$753LATAM Airlines
Tue, Aug 11 - Wed, Aug 26
Delta Logo
6:00 am - 4:43 am
ROA
-
UIO
23h 43m
2 stops
Delta Logo
12:59 am - 11:50 pm
UIO
-
ROA
21h 51m
1 stop
$768Delta
Tue, Aug 11 - Wed, Aug 26
Delta Logo
11:20 am - 4:43 am
ROA
-
UIO
18h 23m
2 stops
Delta Logo
12:59 am - 11:50 pm
UIO
-
ROA
21h 51m
1 stop
$802Delta
Sun, Apr 5 - Tue, Apr 28
Multiple Airlines Logo
3:14 pm - 4:30 pm
ROA
-
GIG
24h 16m
2 stops
Multiple Airlines Logo
5:00 am - 12:22 am
GIG
-
ROA
20h 22m
3 stops
$4,797Multiple Airlines
Sun, Apr 5 - Tue, Apr 28
Multiple Airlines Logo
6:00 am - 6:05 am
ROA
-
GIG
23h 05m
3 stops
Multiple Airlines Logo
5:00 am - 12:22 am
GIG
-
ROA
20h 22m
3 stops
$4,812Multiple Airlines
Booking Insights

KAYAK's insights & trends for Roanoke to South America flights

Get data-powered insights and trends into flights from Roanoke to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Roanoke to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Roanoke to South America were found on American Airlines ($634) and United Airlines ($673).

Good to know

Low seasonJuly
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly with an average 7% increase in price.

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Roanoke to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Roanoke to South America

 
Need help choosing which airline to fly with from Roanoke to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8242 reviews
7.2Food
8.5Crew
7.9Comfort
8.1Boarding
7.8Entertainment
Airline reviews

Everything was good except wifi and a leaking drink chiller. The floor was all wet and my bag was soaked. Did not notice until debarking. Have not heard back from Delta. Even though this was leg one of an international flight in first class, they denied access to their Sky Club - very disappointing!

6.0 GoodAnonymous, Feb 2026
RDU - SEA
Read more Delta reviews

Everything was good except wifi and a leaking drink chiller. The floor was all wet and my bag was soaked. Did not notice until debarking. Have not heard back from Delta. Even though this was leg one of an international flight in first class, they denied access to their Sky Club - very disappointing!

The staff was fine. The plane was extremely tight, and I paid for the wifi and it did not work at all. I was actually going to ask for a refund.

two hour delay and the Delta representative on the PA system was unable to understand

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

2+hrs delay without any reason provided and a cramped flight

We waited an hour on the runway to get a gate in Orlando

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

Flight was delayed due to crew being not on time

Flight crew issues delayed my flight by 2 1/2 hours. Causing me to miss my connection.

The staff on board and gate was nice - a welcome change from the usual. We also arrived early, which was a great benefit, given that it takes 30 minutes plus to get bags at SRQ.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

On board crew was very good. Crew was friendly, snacks were good, especially the chips. Seats seemed a bit cramped. Boarding seemed unorganized, as we were instructed to get to the gate an hour early and then just stood around until boarding.

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor, the airline was not able to help me move flights.

The flight was late. Please do not delay next time.

Lack of gluten free options in food service. I have Celiac disease and it appears you no longer offer special meals for people with dietary restrictions. I am a frequent flyer traveling into and out of Omaha airport. I have noticed over the course of several months that although our flight typically arrives ahead of schedule (awesome job AA!) - we typically sit on the runway for several minutes waiting for the ground crew to get in place. Not sure if it is a ground crew issue or a gate availability issue (due to construction at this airport). Seems to be more of a ground crew being on time issue.

Arrived early picked up my bag in a few minutes- great trip - thank you

Flight boarded, departed and landed on time. Excellent service from flight attendant in FIRST

Boarding is always an ordeal. Less dogs on flights. I am highly allergic to dogs and cats. Why are there so many animals these days?

Flight to Tampa was delayed taking off due to plane arriving late but no other issues

There was a delay with the plan which cause the flight to leave later and once arrived in Chicago there was another delay and some passengers missed their connecting flights

Massimo, flight attendant was very authentic, attentive - wonderful. Food/wrap was just okay.

Worst experience ever. Flight could not land in Charlotte for what we were told was a ground stop. Had to be diverted to Raleigh to refuel. Strangely during ground stop, our connecting flight had no issue taking off on time causing us to miss our flight. We were told there were no other flights that day to our final destination and that two days out was the next one. The only flights to get us there were from Chicago the next morning. Completely opposite direction but it was a direct flight. So we get flown to Chicago and have to find a hotel in our own dime. The flight in the morning was also delayed. Thankfully only a short time. The non too of all this, our luggage did not arrive by the time we were there. Communication was terrible, through the entire trip. Complete incompetence. Will never fly American again.

Horrible. Got delayed many hours because their pilot wasn't trained for night landing at the airport and a rain delay made it a night landing. We have to wait hours for a qualified crew. They give us 12 dollar meal vouchers but most everything in the airport was closed and definitely more expensive than the vouchers.

I am an AA flyer for a very long time... AA has yet to disappoint.

Everything you need to know for your flight to South America

Information on your arrival and departure airports