$636 Find Cheap Flights from Roanoke to South America

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to South America departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South America

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Free to useThere are no hidden charges or fees.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Roanoke to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Rio de Janeiro
Rio de Janeiro2 stops$1,180
Santiago
Santiago1 stop$810
Rio de Janeiro
Rio de Janeiro2 stops$1,180
Santiago
Santiago1 stop$810

Book Cheap Roanoke to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to South America

Sat, Feb 21 - Fri, Feb 27
United Airlines Logo
10:15 am - 12:30 amROA-UIO
38h 15m2 stops
United Airlines Logo
1:35 am - 9:30 pmUIO-ROA
19h 55m2 stops
$636United Airlines
Find Deal
Sun, Apr 12 - Mon, Apr 20
Delta Logo
7:50 pm - 8:09 pmROA-UIO
25h 19m1 stop
Delta Logo
11:20 pm - 10:53 pmUIO-ROA
22h 33m2 stops
$654Delta
Find Deal
Sun, Feb 22 - Fri, Feb 27
American Airlines Logo
7:33 am - 11:33 pmROA-UIO
16h 00m2 stops
American Airlines Logo
12:54 am - 9:26 pmUIO-ROA
20h 32m2 stops
$675American Airlines
Find Deal
Sun, Apr 12 - Mon, Apr 20
American Airlines Logo
5:05 am - 8:45 pmROA-UIO
16h 40m2 stops
American Airlines Logo
11:40 pm - 4:08 pmUIO-ROA
15h 28m2 stops
$693American Airlines
Find Deal
Sun, Apr 12 - Mon, Apr 20
LATAM Airlines Logo
6:00 am - 8:00 pmROA-UIO
15h 00m1 stop
LATAM Airlines Logo
11:20 pm - 7:15 pmUIO-ROA
18h 55m1 stop
$725LATAM Airlines
Find Deal
Sun, Apr 12 - Mon, Apr 20
LATAM Airlines Logo
6:00 am - 8:00 pmROA-UIO
15h 00m1 stop
LATAM Airlines Logo
9:11 am - 11:49 pmUIO-ROA
13h 38m2 stops
$727LATAM Airlines
Find Deal
Sat, Feb 21 - Sat, Feb 28
Multiple Airlines Logo
3:55 pm - 5:17 amROA-UIO
13h 22m2 stops
Multiple Airlines Logo
7:00 pm - 7:18 pmUIO-ROA
24h 18m2 stops
$754Multiple Airlines
Find Deal
Sun, Apr 12 - Mon, Apr 20
Multiple Airlines Logo
8:00 pm - 11:25 pmROA-UIO
28h 25m2 stops
Multiple Airlines Logo
11:30 am - 1:58 pmUIO-ROA
25h 28m3 stops
$1,178Multiple Airlines
Find Deal
Sat, Feb 21 - Fri, Feb 27
Avianca Logo
10:15 am - 8:05 pmROA-UIO
33h 50m3 stops
Avianca Logo
4:00 am - 8:07 pmUIO-ROA
16h 07m2 stops
$2,456Avianca
Find Deal
Sat, Feb 21 - Sat, Feb 28
Avianca Logo
10:15 am - 8:05 pmROA-UIO
33h 50m3 stops
Avianca Logo
11:30 am - 8:07 pmUIO-ROA
32h 37m3 stops
$2,969Avianca
Find Deal
Booking Insights

KAYAK's insights & trends for Roanoke to South America flights

Get data-powered insights and trends into flights from Roanoke to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Roanoke and South America?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Roanoke to South America.

There are 2 airlines that fly nonstop from Roanoke to South America. They are American Airlines and Delta. The cheapest airline for this route is American Airlines, with the best round-trip deal found costing $410 and arriving in Bogotá (BOG). On average, American Airlines offers the best prices for nonstop flights between Roanoke and South America.

Which airlines provide the cheapest flights from Roanoke to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Roanoke to South America were found on United Airlines ($636) and Delta ($654).

Find deals

Good to know

Low seasonJuly
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly with an average 62% increase in price.

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Roanoke to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally at night, when round-trip flights cost $473 on average. On average, there is no price difference when choosing to fly in the morning or the evening on this flight route. The most expensive time of day to fly to South America is generally in the evening, which is peak travel time and where the average cost of a ticket is $733.

Reviews of the top airlines flying from Roanoke to South America

 
Need help choosing which airline to fly with from Roanoke to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8001 reviews
7.9Entertainment
7.9Comfort
7.3Food
8.5Crew
8.2Boarding
Airline reviews

I truly love flying with Delta. They have always treated me with the upmost respect

10.0 ExcellentMAYRA, Nov 2025JFK - MIA
Read more Delta reviews

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

Everything went well and was good. Nothing exceptional, but no complaints either. Cheap seats are pretty comfortable.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

The customer service before board was very rude and when I expressed my concerns about making the connecting flight she laughed and told me I bought the wrong ticket. I explained once it showed the flight was delayed it no longer let me change seats or anything. I was trying to upgrade to make sure I would get to the next gate on time.

Non stop on long haul is the way to go. Great experience

The aircraft interior is old and tired on this aircraft. The entertainment system never worked despite the crews attempt to reset the system.

The flight used a B767 with a very old interior from before 2014. The entertainment system did not work at all during the flight despite attempts to reset the system. It was like they flew this route just to be competitive.

Old plane and old configuration/seats but still comfortable for a morning flight

We loved the steward on the plane. He made the night enjoyable

I enjoyed the extra leg room compared to other airlines. The first stewards made my daughter’s birthday special by giving her an extra snack. Then the last one coming home from Chicago to Appleton made our night really enjoyable Thanks for making our trip enjoyable

The flight was smooth, the pilot kept us informed about delays and we arrived more of less on time

Flight delay was communicated before leaving for airport which caused it to be a non-event. Great flight and crew!

Did not get any refreshments. Crew was very nice but limited. Small seats

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

Wish a flight with more than 2 hours with some snack rather than just cookie/biscuit.

The flight attendant, a black woman with curly hair who sat near Row 21, was wonderful and kind.

It was good..clean, comfy seat. Friendly warm welcoming crew. Was able to check my cabin luggage at the gate which I was able to pickup in a decent time from baggage claim. The app gave all updates from delays to baggage claim info. Overall smooth flight.

Flight was delayed leaving Dallas. Arrived about 2 hours later than scheduled.

Everything you need to know for your flight to South America

Information on your arrival and departure airports

Roanoke (ROA)