$398 Find Cheap Flights from Roanoke to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to South America departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Roanoke to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Rio de Janeiro
Rio de Janeiro2 stops$1,084
Santiago
Santiago2 stops$877
Guayaquil
Guayaquil2 stops$637
Rio de Janeiro
Rio de Janeiro2 stops$1,084
Santiago
Santiago2 stops$877
Guayaquil
Guayaquil2 stops$637

Book Cheap Roanoke to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to South America

Fri, Feb 13 - Tue, Feb 17
American Airlines Logo
6:04 pm - 2:30 pm
ROA
-
GYE
20h 26m
2 stops
American Airlines Logo
3:30 pm - 11:34 am
GYE
-
ROA
20h 04m
2 stops
$637American Airlines
Fri, Feb 13 - Wed, Feb 18
American Airlines Logo
8:00 pm - 2:30 pm
ROA
-
GYE
18h 30m
2 stops
American Airlines Logo
3:30 pm - 10:37 am
GYE
-
ROA
19h 07m
2 stops
$652American Airlines
Tue, May 5 - Thu, May 7
United Airlines Logo
7:59 pm - 11:25 pm
ROA
-
UIO
28h 26m
2 stops
United Airlines Logo
12:35 am - 11:44 pm
UIO
-
ROA
22h 09m
2 stops
$726United Airlines
Tue, May 5 - Thu, May 7
LATAM Airlines Logo
11:08 am - 4:43 am
ROA
-
UIO
18h 35m
2 stops
LATAM Airlines Logo
12:59 am - 2:42 pm
UIO
-
ROA
12h 43m
1 stop
$758LATAM Airlines
Sat, Mar 21 - Thu, Mar 26
United Airlines Logo
7:50 pm - 7:50 am
ROA
-
SCL
59h 00m
2 stops
United Airlines Logo
9:45 pm - 9:43 am
SCL
-
ROA
36h 58m
2 stops
$877United Airlines
Wed, Feb 11 - Tue, Feb 24
LATAM Airlines Logo
6:00 am - 5:35 am
ROA
-
SCL
21h 35m
2 stops
LATAM Airlines Logo
11:10 pm - 10:30 am
SCL
-
ROA
13h 20m
1 stop
$976LATAM Airlines
Sun, Mar 15 - Sun, Mar 22
Avianca Logo
7:50 pm - 7:05 am
ROA
-
GIG
34h 15m
3 stops
Avianca Logo
8:45 pm - 7:02 pm
GIG
-
ROA
23h 17m
3 stops
$1,335Avianca
Sun, Mar 15 - Sun, Mar 22
Avianca Logo
7:50 pm - 12:40 am
ROA
-
GIG
27h 50m
2 stops
Avianca Logo
8:45 pm - 7:02 pm
GIG
-
ROA
23h 17m
3 stops
$1,507Avianca
Fri, Feb 13 - Mon, Feb 16
Multiple Airlines Logo
2:47 pm - 2:30 pm
ROA
-
GYE
23h 43m
3 stops
Multiple Airlines Logo
3:30 am - 8:07 pm
GYE
-
ROA
16h 37m
2 stops
$2,240Multiple Airlines
Fri, Feb 13 - Tue, Feb 17
Multiple Airlines Logo
2:47 pm - 2:30 pm
ROA
-
GYE
23h 43m
3 stops
Multiple Airlines Logo
10:25 am - 8:07 pm
GYE
-
ROA
33h 42m
3 stops
$2,541Multiple Airlines
Booking Insights

KAYAK's insights & trends for Roanoke to South America flights

Get data-powered insights and trends into flights from Roanoke to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Roanoke to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Roanoke to South America were found on American Airlines ($637) and United Airlines ($726).

Good to know

Low seasonJuly
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly with an average 8% increase in price.

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Roanoke to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Roanoke to South America

 
Need help choosing which airline to fly with from Roanoke to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8124 reviews
8.5Crew
8.1Boarding
7.2Food
7.9Comfort
7.8Entertainment
Airline reviews

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

10.0 ExcellentDr. Simon, Jan 2026
LAX - JFK
Read more Delta reviews

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

Timing, quality of service, promptness and courtesy of the staff

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

delta last minute gave me a boarding pass for a different flight with no confirmation that they were changing it

The flight was comfortable and uneventful, which is what I desire

The service from the flight attendants were of supreme quality. They greeted and treated everyone with a wide smile. This is totally absent nowadays. Kudos to them!!!!

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

Very large passenger too space from my own seat. Arm board couldn’t be lowered because of his size. It wads very uncomfortable trip, as the flight was full couldn’t move anywhere having back pain because of the position in which I was the entire flight.

was sitting in the jet bridge for 10 minutes in -20 degree weather waiting for my bag

Outdated equipment in disrepair, wifi inoperable. Broken seats, taped air vents, generally poor condition, the 717 showed its age and lack of upkeep.

Comfort in exit seat was excellent. FLight crew and flight were excellent. However exit seat tray table was broken so could not use it. Entertainment monitor did not work at all despite attempts to reset it.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor, the airline was not able to help me move flights.

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

No gates avail at DFW so our incoming had to wait 30 mins for a plane to push back because they Had mechanical. We boarded 90 mins delayed and then we had a mechanical. Come on American…do better. Also at my seat the tray table had not been cleaned. Floor had not been cleaned. But captain and flight Att were very picture and apologetic.

Crew was helpful and cheerful especially when they had no refreshments to work with. The plane was never serviced and had nothing but limited water and coffee onboard. For the price point, a concern of services.

Flight was smooth, quick and felt safe. The 2 delays not happening would have been better but I guess that happens in the airline industry

Flight was canceled. I asked to be rerouted to OKC and then took an Uber.

AA did not allow to board a flight because my connecting flight from DFW had been canceled. I got on another flight to another city. No service on the plane and I did not use their entertainment system.

On time on a day with lots of weather cancellations on other flights. Thank you for getting me home during a winter storm!

Don't change gate multiple times make people run across the airport. Announce delays in a timely manner. Have maintenance crew ready. Don't delay and keep passengers on the plane for 3 hrs. on tarmac.

The plane was experiencing problems with the HVAC system, it was very cold in the front of the plane and very hot in the back.

My flight to London from Philadelphia was cancelled due to weather.

The attendants were kind and helpful. A sugar-free drink would have been very welcome.

Everything you need to know for your flight to South America

Information on your arrival and departure airports