$434 Find Cheap Flights from Roanoke to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to South America departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Roanoke to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Rio de Janeiro
Rio de Janeiro1 stop$991
Santiago
Santiago2 stops$979
Guayaquil
Guayaquil2 stops$571
Rio de Janeiro
Rio de Janeiro1 stop$991
Santiago
Santiago2 stops$979
Guayaquil
Guayaquil2 stops$571

Book Cheap Roanoke to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to South America

Mon, Dec 8 - Fri, Dec 12
American Airlines Logo
5:03 pm - 11:06 pmROA-GYE
30h 03m2 stops
American Airlines Logo
6:10 am - 8:34 amGYE-ROA
26h 24m2 stops
$571American Airlines
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Mon, Dec 8 - Fri, Dec 12
American Airlines Logo
5:03 pm - 11:06 pmROA-GYE
30h 03m2 stops
American Airlines Logo
6:10 am - 10:34 amGYE-ROA
28h 24m2 stops
$637American Airlines
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Wed, Dec 24 - Tue, Jan 13
LATAM Airlines Logo
6:00 am - 5:35 amROA-SCL
21h 35m2 stops
LATAM Airlines Logo
4:35 am - 12:04 amSCL-ROA
21h 29m2 stops
$979LATAM Airlines
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Mon, Jan 12 - Mon, Jan 26
Delta Logo
11:24 am - 8:20 amROA-GIG
18h 56m1 stop
Delta Logo
9:30 pm - 3:07 pmGIG-ROA
19h 37m1 stop
$991Delta
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Thu, Jan 1 - Thu, Jan 8
LATAM Airlines Logo
6:00 am - 11:00 pmROA-UIO
17h 00m2 stops
LATAM Airlines Logo
7:00 pm - 10:44 amUIO-ROA
15h 44m2 stops
$992LATAM Airlines
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Wed, Dec 24 - Wed, Jan 14
LATAM Airlines Logo
6:00 am - 7:40 amROA-SCL
23h 40m1 stop
LATAM Airlines Logo
9:30 pm - 10:44 amSCL-ROA
15h 14m1 stop
$1,002LATAM Airlines
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Wed, Dec 24 - Tue, Jan 13
LATAM Airlines Logo
6:00 am - 7:40 amROA-SCL
23h 40m1 stop
LATAM Airlines Logo
4:35 am - 12:04 amSCL-ROA
21h 29m2 stops
$1,007LATAM Airlines
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Fri, Jan 16 - Mon, Jan 26
Delta Logo
11:24 am - 8:20 amROA-GIG
18h 56m1 stop
Delta Logo
9:30 pm - 3:07 pmGIG-ROA
19h 37m1 stop
$1,031Delta
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Thu, Jan 1 - Wed, Jan 7
United Airlines Logo
6:40 am - 12:30 amROA-UIO
17h 50m2 stops
United Airlines Logo
1:35 am - 2:09 pmUIO-ROA
12h 34m2 stops
$1,266United Airlines
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Thu, Jan 1 - Thu, Jan 8
Multiple Airlines Logo
7:55 pm - 5:55 pmROA-UIO
22h 00m2 stops
Multiple Airlines Logo
2:20 pm - 2:09 pmUIO-ROA
23h 49m3 stops
$4,771Multiple Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Roanoke to South America flights

Get data-powered insights and trends into flights from Roanoke to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Roanoke and South America?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Roanoke to South America.

There are 2 airlines that fly nonstop from Roanoke to South America. They are American Airlines and Delta. The cheapest airline for this route is American Airlines, with the best round-trip deal found costing $410 and arriving in Bogotá (BOG). On average, American Airlines offers the best prices for nonstop flights between Roanoke and South America.

Which airlines provide the cheapest flights from Roanoke to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Roanoke to South America were found on American Airlines ($571) and LATAM Airlines ($979).

Good to know

Low seasonJuly
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 55% increase in price.

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Roanoke to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally at night, when round-trip flights cost $473 on average. On average, there is no price difference when choosing to fly in the morning or the evening on this flight route. The most expensive time of day to fly to South America is generally in the evening, which is peak travel time and where the average cost of a ticket is $733.

Reviews of the top airlines flying from Roanoke to South America

 
Need help choosing which airline to fly with from Roanoke to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8008 reviews
8.1Boarding
7.9Comfort
8.5Crew
7.3Food
7.9Entertainment
Airline reviews

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

8.0 ExcellentAnonymous, Nov 2025SFO - MSP
Read more Delta reviews

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

Service in business class was not impressive. I ordered coffee with dinner and then watched other people get 2 refills before I got my 1 cup of coffee, and only after I pressed the attendant button overhead. Furthermore, the seats in the forward cabin need maintenance on this 737-800: the upholstery is detaching from the seat frame, at least on the backs of seats 1C, 1D.

Plenty of leg room, temperature was great and staff was excellent. Would do it more often.

The ticket agents in West Palm Beach on Friday afternoon Nov. 7th were incredible in getting us on an earlier plane to Atlanta during the government shutdown. Had the taken our original flight we would have missed our connection. She did this on her own, We didn't even have to ask, and she did it all with a smile and showing genuine concern that we would be taken care of. We are very grateful and thankful. We fly often, and now we will be sure to fly Delta.

Flight delayed then cancelled. Misplaced luggage. Still do not have. Rented car 1100 mile drive. I had to buy some overnight Hotels clothes toiletries gas food at my expense. Still not home. Not sure where luggage is. Over 4 hours on hold to Felta

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

Everything went well and was good. Nothing exceptional, but no complaints either. Cheap seats are pretty comfortable.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

More choices on snacks. Built-in video screen to enjoy entertainment choices.

we landed at cmh ten minutes early but had to sit on tarmac for twenty minutes because a plane was at our gate despite the fact that 3 other gates were open.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

I have a gluten allergy so did have any food

I have a gluten allergy so didn't have any food

Loved the crew . Absolutely no complaints. Except for luggage lost

Everything was good The connects, with no blame to crew. Or pilots. I understand they are short staffed. Everything went well for me. I'll be using you guys again in May if not sooner.

this plane was really old, had exit row seats and tray was in arm of seat so super uncomfortable to use. another seat they could t even use the tray it was broke. seat i. front of me had duct tape on it cause seat was ripped open... this plane should either be updated or retired.

We were very rushed by a staff member at the gate when transferring from American Airlines to Fijian. Then the plane stayed put for ages anyhow! The plane was delayed and my bag sent to San Francisco instead of Fiji

Baggage handling poor. Second time this has happened. My bag went to San Francisco instead of Fiji. No apology. Luckily Nadi airport staff are fantastic. My bag arrived in Fiji the next day.

Everything you need to know for your flight to South America

Information on your arrival and departure airports