$48 Find Cheap Flights from San Diego to Missouri

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Diego to Missouri departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Missouri

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Diego to Missouri.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Diego to Missouri.
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Cheap Flights from San Diego to Missouri

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
St. Louis
St. Louis1 stop$147
Kansas City
Kansas City2 stops$220
Springfield
Springfield1 stop$252
Columbia
Columbia2 stops$284
St. Louis
St. Louis1 stop$147
Kansas City
Kansas City2 stops$220
Springfield
Springfield1 stop$252
Columbia
Columbia2 stops$284

Book Cheap San Diego to Missouri Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Diego to Missouri that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Diego to Missouri

Wed, Feb 25 - Wed, Mar 4
Frontier Logo
7:11 am - 3:53 pm
SAN
-
STL
6h 42m
1 stop
Frontier Logo
5:18 pm - 5:31 pm
STL
-
SAN
26h 13m
2 stops
$147Frontier
Fri, Feb 27 - Sun, Mar 1
Frontier Logo
8:35 am - 1:56 pm
SAN
-
STL
27h 21m
1 stop
Frontier Logo
10:11 pm - 1:05 pm
STL
-
SAN
16h 54m
1 stop
$148Frontier
Wed, Feb 25 - Wed, Mar 4
Frontier Logo
7:11 am - 3:53 pm
SAN
-
STL
6h 42m
1 stop
Frontier Logo
5:18 pm - 9:41 pm
STL
-
SAN
6h 23m
1 stop
$158Frontier
Sat, Feb 28 - Sat, Mar 7
Frontier Logo
12:23 pm - 6:51 am
SAN
-
STL
40h 28m
2 stops
Frontier Logo
8:12 pm - 11:08 pm
STL
-
SAN
28h 56m
1 stop
$164Frontier
Tue, Apr 21 - Sat, Apr 25
Multiple Airlines Logo
12:44 pm - 11:59 pm
SAN
-
MCI
9h 15m
1 stop
Multiple Airlines Logo
2:51 pm - 8:04 pm
MCI
-
SAN
7h 13m
1 stop
$224Multiple Airlines
Mon, Mar 30 - Sun, Apr 5
Multiple Airlines Logo
9:58 pm - 11:31 pm
SAN
-
MCI
23h 33m
1 stop
Multiple Airlines Logo
8:28 pm - 12:02 am
MCI
-
SAN
29h 34m
1 stop
$227Multiple Airlines
Thu, Feb 19 - Sun, Feb 22
Alaska Airlines Logo
9:08 pm - 4:22 pm
SAN
-
MCI
17h 14m
1 stop
Alaska Airlines Logo
5:16 pm - 11:59 pm
MCI
-
SAN
8h 43m
1 stop
$257Alaska Airlines
Wed, Feb 25 - Thu, Mar 5
United Airlines Logo
4:10 pm - 11:28 pm
SAN
-
JLN
5h 18m
1 stop
United Airlines Logo
6:24 pm - 10:35 pm
JLN
-
SAN
6h 11m
1 stop
$284United Airlines
Thu, Mar 5 - Wed, Mar 11
United Airlines Logo
8:50 pm - 10:33 am
SAN
-
COU
11h 43m
2 stops
United Airlines Logo
9:05 am - 3:00 pm
COU
-
SAN
7h 55m
1 stop
$284United Airlines
Fri, Mar 6 - Sun, Mar 8
American Airlines Logo
10:35 pm - 10:00 am
SAN
-
SGF
9h 25m
1 stop
American Airlines Logo
6:00 am - 9:58 am
SGF
-
SAN
5h 58m
1 stop
$314American Airlines
Booking Insights

KAYAK's insights & trends for San Diego to Missouri flights

Get data-powered insights and trends into flights from San Diego to Missouri to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from San Diego to Missouri?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from San Diego to Missouri departing in February.

What is the cheapest San Diego to Missouri flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Missouri from San Diego found in the last 72 hours was to Kansas City, at $296 round-trip. The most popular route is from San Diego (SAN) to St. Louis (STL), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $305.

What is the cheapest month to fly from San Diego to Missouri?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Diego to Missouri, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Diego to Missouri is September, when tickets cost $271 (return) on average. On the other hand, the most expensive months are December and July, when the average cost of round-trip tickets is $493 and $427 respectively.

What’s the cheapest day of the week to fly from San Diego to Missouri?

The average price of all round-trip flights from San Diego to Missouri clicked on KAYAK for each day over the last 12 months.

For San Diego to Missouri, Thursday is the cheapest day to fly on average and Monday is the most expensive. Flying from Missouri back to San Diego, the best deals are generally found on Wednesday, with Monday being the most expensive.

How far in advance should I book a flight from San Diego to Missouri?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Diego to Missouri, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Diego to Missouri, you should book around 4 weeks before departure, which saves you about 28% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 14 weeks before departure.

Good to know

Low seasonNovember
Cheapest flight$48
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly with an average 1% increase in price.
Flight from San Diego to Kansas City

FAQs - booking Missouri flights

  • How does KAYAK find such low prices on flights from San Diego to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Diego to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Diego to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Diego to Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Diego to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Diego to Missouri with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Diego to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Diego to Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Missouri?

    The cheapest time of day to fly to Missouri is generally in the evening, when round-trip flights cost $429 on average. Morning departures are around 12% more expensive than evening flights, on average. The most expensive time of day to fly to Missouri is generally in the morning, which is peak travel time and where the average cost of a ticket is $481.

Reviews of the top 5 airlines serving from San Diego to Missouri

 
See real verified KAYAK customer reviews for airlines flying from San Diego to Missouri. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Diego to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4267 reviews
8.1Boarding
7.0Food
8.6Crew
8.0Comfort
7.5Entertainment
Airline reviews

Everything went smoothly and we even arrived a little bit early.

10.0 ExcellentAmy, Jan 2026
DEN - STL
Read more Southwest reviews

Everything went smoothly and we even arrived a little bit early.

Great flight but super high price. Glad it was a business trip and not personal

3 hour delay. Had to change plans and was still delayed.

We got exit row seats both flights. Everything was running on time

The boarding and seat assignment system no longer works for me, but I know it is being replaced. Otherwise, I am good with the overall experience.

The lead steward kept singing about "San Francisco" and hotel California---more annoying than humorous....needs work. Flight was smooth and on time.

San Diego airport is brand new, spacious, airy and very smooth checkin at SW baggage drop.

Crew could have been friendlier, maybe I'm spoiled by SW crews. In flight wifi was good. Would be nice to have more food offerings on a 4 plus hour flight

Ever since Southwest starting charging for bags, passengers don't want to pay to check their bags, so the gate agents have to beg people to check their roller bags now because there's "not enough space". This was a terrible business move by Southwest.

Sacrament staff are always polite and helpful. Airport is easy to maneuver and boarding is straightforward.

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

Delta’s staff is unmatched. From the gate agents, to the pilots, to the flight attendants… all top of the industry.

The flight was delayed for about 2 hrs. Other than it, it was good.

I am extremely disappointed that delta internal pilot manuals now refer to the Gulf of Mexico as the “gulf of America”. You can bow down to the Orange turd on your own. I will never fly delta again

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

The flight used a B767 with a very old interior from before 2014. The entertainment system did not work at all during the flight despite attempts to reset the system. It was like they flew this route just to be competitive.

Delayed flight (1hour) plus a long layover after an overnight flight with no backup plane available.

The boarding process needs to be refined. Sometimes the gate crew calls out the zones and then flip to showing the.zones boarding on the gate monitor display. So, unless you are huddled around the gate lanes watching the monitor, you could miss your boarding zone. Suggest the zones be announced each time a new zone is allowed to board.

The food was terrible this time. Otherwise pleasant, quiet, on-time.

It was a pretty standard flight... until the almost hour and a half spent on the taxi way. I get that the weather has been poor but the delay had nothing to do with the weather and more to do with a plane with several issues tying up the gate. I get that that happens from time to time but this has been EVERY flight I've been on for the past 5 years and I fly 3 to 5 times a year. This isn't just United... it's American, it's Delta. It's an issue with the entire industry. I work for UPS and packages on a cargo plane get better service than people do these days. Anymore I HATE flying.

The flight crew where really good. Better then the crew from BNE to SFO

left on time, reasonable boarding process arrived early luggage came out quickly

I’m so sorry, I can’t remember her name, I believe it was Dimpti. She was stellar, also a mature Asian flight attendant, lots of flowers in her hair, just as amazing! But literally the crew was AWESOME . Only downside is there weren’t any charging outlets. Maybe I needed to ask a flight attendant , but it would’ve been nice to have one easily accessible.

I boarded flight UA#1318 at Sacramento International Airport going back to Houston TX. The flight was scheduled at 5:10am. I was able to check in virtually using the United Airlines app. When I entered the airport, there was no one outside assisting with checked bags as it was for Delta Airlines. Immediately upon entering, there was a LONG, EXTREMELY LONG line to the kiosks to get boarding passes. I stand in line to get boarding passes then had to move to ANOTHER EXTREMELY LONG line to get my bags checked in. While standing in this line, we noticed an agent taking customers to 3 at a time to her station to check their bags in. Lucky for me, she called me back, checked my bags for me and I was on my way. I then encountered another long line at the TSA check and to avoid I ending up having to sign up for CLEAR to bypass it. So glad, I did.,...Both of my flights were great with no issues, butthe check in progress at Bush Airport was so much smoother. Check-in at SMF airport needs to be anaylzed and corrected. Do better United, I know you can....thanks

Pushed back only to get deplaned due to a tire damaged by ground crew. They did at least go pretty fast. The bathrooms should be banned under the Geneva convention. No room to even sit straight on the toilet. The under-seat entertainment units block what little leg room there is.

Essy to get on. The hostess gave very little pop, the plane was late getting in, and we are still waiting for our bags. This sucks. :/

United airlines has the best customer experience from booking to arrival. I always fly United airlines. The mileage program is excellent

Older aircraft, no meal, only food was for purchase. Not impressed United.

This flight captain and crew were amazing, started ahead of time of departure and reached 30 mins before arrival time. Amazing!

The entertainment options were at best, fair. It was exactly the same as my outbound flight. It would have been more entertaining if there were some series from Apple TV, HBO, Showtime or other carriers for me to catch up with.

The flight was on time and arrived early. The crew were friendly and helpful.

Overall experience was great. Flights were almost on time in departing and we arrived at our destination as scheduled. No issues with amenities or flight crew. Everything went well as as expected. Will fly again with American Airlines in the future!

Horrible. Both legs of my flight were delayed more than 6 hours. No compensation, no screens on the plane, and the plane was not clean.

The flight was smooth, the pilot kept us informed about delays and we arrived more of less on time

The flight was flawless and we even arrived between 20 and 25 minutes early!

Always seated jammed in rear of aircraft Admirals Club food at DFW terminal D was absolute worst food experience and I pay $600/year to eat this dried out junk

Mostly good. Flight was crowded but Airline personnel were very friendly & accommodating. It would be good to have savory snacks rather than just sweet Biscoff cookies.

It was a red eye flight, so no meals were provided, but it was fine with snacks. The seats felt cramped and almost too narrow.

Very well recently! Frontier is improving and less harrassing customer on luggages! Positive!

Good for a budget airline! It was easy to get on, staff was really nice. Can’t say anything about the food or entertainment because it wasn’t available, which is fine.

I am writing to express my disappointment with my recent Frontier Airlines flight. I was charged $99 at the gate because my bag was said to be too large, yet once onboard there was no available overhead bin space, and I was required to place the bag under the seat in front of me anyway. This made the charge feel unnecessary and unfair. Additionally, before the flight even took off, I was asked to move from the seat I paid for into a middle seat so another passenger and her cat could have my seat to themselves. I was not offered compensation or an explanation for being moved from a paid seat. Between the unexpected bag fee and being forced to give up my seat, this experience fell well below acceptable customer service standards. I would appreciate a review of this situation and appropriate compensation.

It was costly and difficult to check in. $85 to take a small suitcase with me, carry on or checked and $75 on the return trip, Plus $25 if I didn't check my self in check in $25, because I couldn't do it on the kiosk. Small very uncomfortable seats, waited on the runway for near an hour each way. It was my worst flight to date.

It was ok. It was expensive to check 2 bags ($75.00 per bag), and then it took a long time to wait for shuttle to take us from one terminal to the terminal where the plane was taking off at LAX. And all of this for a flight where we had to pay for any food or drink that was not water.

When I wanted to check in 3 hours prior to boarding time, the employees mentioned “a little over an hour delay” so I waited for an hour then I went to go look for food in the terminal and most people from that flight were in the same area looking for food. Finally I decided after food to check to see if it’s anytime closer and now it’s 2 mins until boarding closes?! What are you kidding me? I didn’t receive anything via sms about boarding now nor via email or on the intercom. I luckily made it through, barely, and then there’s no room for my carry on mind you I’m in the very first row so I had to place my purse in one further row back and my carry on sections down. Not sure who pays for better seats to get your stuff placed all over the plane but that was the worst experience I’ve ever had flying with anyone.

This airline sucks. They offer low rates then charge you for everything, the app does not work well, the seats are the most uncomfortable. Maintenance issues on the flight, and you still have to sit through their credit card commercials. People are nice enough but does not make up for overall poor experience.

Cancelled flight after I arrived at airport after 75 min drive and parking. Next flight was 4 days in the future. Had to scramble and buy a much more expensive flight on another carrier.

I liked the turn-style feature at gate 209B at LAX. Very efficient process. The gate staff also made several, clearly directed announcements so I felt very informed.

The seats were awful, hard plastic covered in sheet vinyl. The airline tries to scam you into paying extra to get seat together when the flight wasn’t full. They were going to separate a family with young children but my wife who had a row to herself gave up her seat so the young mom could be with her young boys. I’m never giving this airline my money again.

Everything you need to know for your flight from San Diego to Missouri

Information on your arrival and departure airports