$80 Find Cheap Flights from San Diego to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Diego to South Carolina departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Diego to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Diego to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from San Diego to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$344
Myrtle Beach
Myrtle Beach1 stop$394
Greenville
Greenville1 stop$383
Columbia
Columbia1 stop$333
Florence
Florence1 stop$661
Charlotte
Charlotte1 stop$335
Charleston
Charleston1 stop$344
Myrtle Beach
Myrtle Beach1 stop$394
Greenville
Greenville1 stop$383
Columbia
Columbia1 stop$333
Florence
Florence1 stop$661
Charlotte
Charlotte1 stop$335

Book Cheap San Diego to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Diego to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Diego to South Carolina

Wed, Jun 3 - Tue, Jun 23
Delta Logo
10:25 pm - 9:15 am
SAN
-
CAE
7h 50m
1 stop
Delta Logo
5:35 am - 9:33 am
CAE
-
SAN
6h 58m
1 stop
$333Delta
Sat, Jun 6 - Sat, Jun 13
American Airlines Logo
9:25 pm - 8:16 am
SAN
-
CAE
7h 51m
1 stop
American Airlines Logo
7:22 pm - 11:59 pm
CAE
-
SAN
7h 37m
1 stop
$334American Airlines
Sun, Jun 7 - Mon, Jun 29
Frontier Logo
6:25 am - 5:55 pm
SAN
-
CLT
8h 30m
1 stop
Frontier Logo
10:14 pm - 9:09 am
CLT
-
SAN
13h 55m
1 stop
$335Frontier
Sat, Jun 20 - Sat, Jun 27
Frontier Logo
8:29 pm - 9:25 pm
SAN
-
CLT
45h 56m
2 stops
Frontier Logo
6:00 am - 6:50 pm
CLT
-
SAN
15h 50m
1 stop
$343Frontier
Wed, Aug 12 - Sat, Aug 15
Delta Logo
10:55 am - 9:41 pm
SAN
-
AGS
7h 46m
1 stop
Delta Logo
5:45 am - 9:43 am
AGS
-
SAN
6h 58m
1 stop
$349Delta
Sat, May 23 - Sat, May 30
American Airlines Logo
10:28 pm - 8:16 am
SAN
-
CAE
6h 48m
1 stop
American Airlines Logo
7:21 pm - 11:59 pm
CAE
-
SAN
7h 38m
1 stop
$361American Airlines
Sat, May 23 - Sat, May 30
United Airlines Logo
10:34 am - 9:16 pm
SAN
-
CAE
7h 42m
1 stop
United Airlines Logo
10:31 am - 6:32 pm
CAE
-
SAN
11h 01m
2 stops
$366United Airlines
Thu, Jun 4 - Wed, Jun 10
United Airlines Logo
9:05 pm - 8:51 am
SAN
-
CHS
8h 46m
1 stop
United Airlines Logo
11:31 am - 6:30 pm
CHS
-
SAN
9h 59m
1 stop
$393United Airlines
Sat, May 23 - Sat, May 30
Southwest Logo
8:20 pm - 10:20 am
SAN
-
CHS
11h 00m
2 stops
Southwest Logo
7:15 pm - 11:15 pm
CHS
-
SAN
7h 00m
1 stop
$396Southwest
Wed, Jul 15 - Tue, Jul 21
Southwest Logo
7:50 am - 7:35 pm
SAN
-
CHS
8h 45m
2 stops
Southwest Logo
4:15 pm - 10:40 pm
CHS
-
SAN
9h 25m
2 stops
$401Southwest
Booking Insights

KAYAK's insights & trends for San Diego to South Carolina flights

Get data-powered insights and trends into flights from San Diego to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from San Diego to South Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from San Diego to South Carolina departing in May.

What is the cheapest month to fly from San Diego to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Diego to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Diego to South Carolina is January, when tickets cost $134 (return) on average. On the other hand, the most expensive months are March and November, when the average cost of round-trip tickets is $308 and $308 respectively.

How far in advance should I book a flight from San Diego to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Diego to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Diego to South Carolina, you should book around 4 weeks before departure, which saves you about 49% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Good to know

Low seasonFebruary
Cheapest flight$80
Best time to beat the crowds but there is an average 24% increase in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from San Diego to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from San Diego to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Diego to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Diego to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Diego to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Diego to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Diego to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Diego to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Diego to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from San Diego to the following destinations at these prices or less: Charlotte $244 one-way - $445 round-trip

Reviews of the top 5 airlines serving from San Diego to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from San Diego to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Diego to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4314 reviews
8.0Comfort
8.1Boarding
7.5Entertainment
7.0Food
8.6Crew
Airline reviews

The entire experience from boarding to landing was amazing! The crew were very friendly. Will definitely be back.

10.0 Excellentlarry, Apr 2026
LGB - PHX
Read more Southwest reviews

The entire experience from boarding to landing was amazing! The crew were very friendly. Will definitely be back.

Delayed flight, lack of information, boarding process is a mess as is the carryon luggage causing issues when leaving the plane….just a poor experience.

Comfortable. Easy. No problems. Just wish they had gf options for snacks.

The crew was very kind and made going to Hawaii relaxing and fun to look forward to! Thank you Southwest for a pleasant flight!

Terrible. Even though there’s assigned seating now, they are still the slowest boarding airline of anyone.

It was good from LAX to Phoenix, But the connection in Phoenix to Tulsa was not that great. The staff on both flights were great. The choice of free entertainment was ok nothing to brag about. The 45 min delay because of some electrical issue wasn't great from Phoenix to Tulsa. We sat there with hardly any air, The seat I had was between windows so the side of the plane pushed in on you. My being a bigger man it then made the seating area uncomfortable. The seats on the plane had no power to connect to recharge your phone or anything. I would recommend that they should look into a slot or clamp to hold your phone to enjoy while watching the entertainment choices hands-free. Also make it possible to raise the inner seat by the window be able to raise the arm rest up to make more room for larger people to set more comfortably. I would also say other then that stop price gouging the airfare or nickel and diming everything. Not fair for people having to fly for emergencies and be paying for higher prices due to the season or holidays. Your making your money either way and the cost of flying is still going to be the same regardless if there's 100 people or 200 people.

Southwest was greaat! The most expensive but the least upsetting for those we were flying to see.

Boarding was easy. The seats are small and fairly uncomfortable

The problem with the seat assignments is that there were a lot of rows in the front that were empty but my row at the back was full. Just not so pleasant.

Good but I prefer choose your own seat. With the new assigned seats they should board from the back I see no advantage to this new boarding. Just like every other airline

While they turned off most cabin lights to allow people to sleep, I was bothered by how bright the side lights still were. It was still quite bright for me in a window seat, when I wish I could have slept!

Generally on time departures and arrivals, clean planes, sky miles membership provides great benefits (complimentary upgrades, etc).

N Everything was perfect from boarding to assistance to baggage in Tampa

Loved the crew! Sucks that we went from 1 hour and 8 minute layover to a 3 hour layover. But weather sucks like that.

Fast, lovely scenery, great info on the Delta flight screen about landmarks we were flying over. Great landing!

Long flight but comfortable and not freezing as I have experienced on Hawaiian flights to the islands. They gave us blankets just in case. Nice touch.

I am still at the Airport! Delayed Delayed and Delyaed

I took seat 15A in anticipation of window seat, there is no window.

Flight late, the waited for a long time for “personal” to arrive at gate to dock the plane in Rochester. So annoying. This flight was expected, why aren’t personel available for the jet bridge?

My recent experience was excellent on Delta! I flew with Delta Comfort and I was really comfortable in my seat. I enjoyed the in-flight service. The flight attendants were so friendly and hospitable. I love the snack on the flight as well. This was my first time flying on Delta and I will definitely consider flying with them again.

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

Outstanding service, efficient & friendly crew, flight was safe, comfortable & on time

It was a red-eye, but the flight felt surprisingly quick. The seats were very comfortable, and that made resting much easier. I also want to thank the gentleman seated next to me, who graciously moved so my mom could sit beside me. We slept almost the entire way. The cabin crew was respectful in not disturbing us, while also being courteous and professional throughout. Thank you, United.

Boarding was again a "free for all". We were boarding group 4, and almost the entire plane was able to board before us. It's a shame that someone who follows the rules, gets the short end of the stick. Not fair.

It was perfect! I've never flown with United before, but I definitely will in the future

I had a cancelled flight because of technical issues going to my destination, and a delayed flight coming home. All told it wasn’t a total bust.

Awful. No counter attendants. No dinner offered due to delays.

They delayed the flight from 9:00 to 11:55 At 11:45 they canceled the flight. I paid a premium price for the tickets with poor service

My flight was canceled a few hours before boarding. I was rebooked on Copa airlines and missed an important meeting .

OK, we were delayed and had to de plane and reboard.

Purchased through 3rd party vendor which made everything difficult. Unable to check in online. Unable to get flight updates easily, tsa precheck information didn’t carry through, longer time to check in in person. Entertainment looked good but had to purchase conventional headphones to view.

Boarding was fast, easy, and we landed early. The entertainment system was very buggy and kept resetting throughout the flight.

Not having an assigned seat until boarding and then having to check my bag.

Flight emergency landed in Chicago due to “Odor” in back of plane . Had to buy ANOTHER TICKET to get to Boston cash out of my own pocket . Then they would notchange my return flight time without a 400. Charge!!!! Insulting.

I purchased ticket so our daughter ( a minor) can sit next to her mother. No help at gate after kayak insisted that this could be done. She ended sitting by herself

Flight was as expected. But it was delayed an hour. Also, my luggage got damaged. So that sucked especially since the damage made navigating the airport difficult. Walking to get ground transportation is sooo far away now and my checked bag was difficult to carry.

we were an hour delayed after boarding and given no reason. Headsets cost money. Also there were openrows with no one setting in them but we were told we were not allowed to swtich.

Crew was very friendly. Did not like being jammed in the back middle seat. Don’t understand why I can not select an aisle for free based on first come first serve. Also first time I’ve been on a flight which attempted land then circled Detroit airport multiple times.

Terrible. There was a lot of misleading information regarding ticketing, seat upgrades, & boarding group. I also expect my seat will recline. I have back problems & it is very painful for me of the seat doesn’t recline. In addition, when I choose a fare that allows me a carry-on bag, I expect to be able to carry it on. Not be forced to check it. Thos happened on my flight to MCO & back to Boston. Not sure I will ever fly JetBlue again. Further I bought the ticket through hat deal. I will NEVER do that again. They were incapable of providing an accurate record locator # for either leg of the trip. I had to call them before each flight with me VERY stressed about whether I would actually be able to get on my flight. Who does that? Who books flight & then FAILS to give an accurate record locator? Twice!

The flight was delayed 4 hours and the JetBlue people at the counter kept lying to us and telling us it was due to weather however all other flights were going in and out of NY and FL. Then they lied that the plane had to stop to refuel. Then they lied and said the plane needed a tire change. JetBlue is the worst. Then they gave a lot of people meal vouchers however I didn’t know they did that and they didn’t offer anything to me.

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

Boarding gate at LAX was too crowded—two gates next to one another

On time departure and early arrival. Flight attendant very nice.

The SFO Lounge crew were amazing. The bartender Faris was great. Thanks!

Was not able to do a online check-in because the American Airlines system doesn't store our visa or other passport information, allowing us to have a trouble-free check-in. We were forced to have to check-in at the counter which Changes are upgrade status given that we were not able to check in much earlier.

Good flight, seated and had a water within 5 minutes. Crew was hospitable.

We left at 1030 am pacific from LA and supposed to land at 7 pm Eastern in NY. They made a detour, stopped in Philadelphia and didn’t land till 1130 PM Eastern!!! Worst flight experience with no pilot communication with no explanation as to what was going on. Everyone was very frustrated to say the least.

Flight boarded from Gate 159B, the farthest gate in the LAX Bradley Terminal. While the flight operated on time, the first class cabin attendant made no recognition of my being an Advantage Executive Platinum member.

The flight itself was excellent but the gate attendant made me check my carryon since she said it was an inch too big. I’ve had no problems with this carryon on recent flights on Qantas, Delta, Austrian, Southwest Airlines even though the overhead bins are the same size. there were other carryons in the bins that also looked larger than mine and there was room left in the bins for more. When I picked up my carryon from baggage claim one of the wheels had broken off.

I was in last row so that is never great bc the person in front of me leaned his seat all the way back into me.

Everything you need to know for your flight from San Diego to South Carolina

Information on your arrival and departure airports