$351 Find Cheap Flights from Santa Ana to the Cayman Islands

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to the Cayman Islands departing on 3/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Santa Ana to the Cayman Islands Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to the Cayman Islands that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to the Cayman Islands

Mon, Mar 23 - Fri, Mar 27
United Airlines Logo
7:45 pm - 12:45 pmSNA-GCM
15h 00m2 stops
United Airlines Logo
4:45 pm - 8:49 pmGCM-SNA
30h 04m2 stops
$771United Airlines
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Mon, Mar 23 - Fri, Mar 27
United Airlines Logo
2:03 pm - 12:45 pmSNA-GCM
20h 42m1 stop
United Airlines Logo
4:45 pm - 8:50 pmGCM-SNA
30h 05m2 stops
$787United Airlines
Find Deal
Wed, Nov 26 - Wed, Dec 3
United Airlines Logo
3:14 pm - 4:30 pmSNA-GCM
22h 16m1 stop
United Airlines Logo
5:45 pm - 11:10 amGCM-SNA
20h 25m2 stops
$788United Airlines
Find Deal
Thu, Mar 19 - Thu, Mar 26
Delta Logo
9:20 pm - 11:35 amSNA-GCM
12h 15m1 stop
Delta Logo
1:00 pm - 10:29 pmGCM-SNA
11h 29m1 stop
$806Delta
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Thu, Mar 19 - Thu, Mar 26
Delta Logo
7:00 am - 11:35 amSNA-GCM
26h 35m2 stops
Delta Logo
1:00 pm - 10:29 pmGCM-SNA
11h 29m1 stop
$811Delta
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Sat, Mar 21 - Sun, Mar 29
WestJet Logo
2:15 pm - 12:44 pmSNA-GCM
44h 29m2 stops
WestJet Logo
1:50 pm - 1:24 pmGCM-SNA
49h 34m2 stops
$913WestJet
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Thu, Mar 19 - Sun, Mar 29
Air Canada Logo
7:20 am - 11:25 amSNA-GCM
26h 05m2 stops
Air Canada Logo
12:30 pm - 8:39 pmGCM-SNA
34h 09m2 stops
$989Air Canada
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Mon, Mar 23 - Sun, Mar 29
Air Canada Logo
7:00 am - 11:25 amSNA-GCM
26h 25m2 stops
Air Canada Logo
12:30 pm - 9:45 pmGCM-SNA
35h 15m2 stops
$1,076Air Canada
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Tue, Mar 3 - Wed, Mar 4
American Airlines Logo
12:33 pm - 12:04 pmSNA-GCM
20h 31m2 stops
American Airlines Logo
3:45 pm - 12:01 pmGCM-SNA
23h 16m2 stops
$2,725American Airlines
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Tue, Mar 3 - Wed, Mar 4
American Airlines Logo
9:47 am - 12:04 pmSNA-GCM
23h 17m2 stops
American Airlines Logo
3:45 pm - 12:01 pmGCM-SNA
23h 16m2 stops
$2,755American Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Santa Ana to the Cayman Islands flights

Get data-powered insights and trends into flights from Santa Ana to the Cayman Islands to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Santa Ana and Cayman Islands?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Santa Ana to the Cayman Islands.

There is just one airline that flies from Santa Ana to the Cayman Islands direct and that is American Airlines. The best round-trip deal found from American Airlines for the route is to George Town (GCM) and costs $888.

Which airlines provide the cheapest flights from Santa Ana to the Cayman Islands?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Santa Ana to the Cayman Islands were found on United Airlines ($771) and Delta ($806).

Good to know

Cheapest flight$351
Flight from John Wayne (Santa Ana) to George Town

FAQs - booking Cayman Islands flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to the Cayman Islands?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to the Cayman Islands.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to the Cayman Islands?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to the Cayman Islands is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to the Cayman Islands?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to the Cayman Islands with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to the Cayman Islands?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to the Cayman Islands up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to the Cayman Islands?

    The cheapest time of day to fly to the Cayman Islands is generally in the morning, when round-trip flights cost $601 on average. Morning departures are around 25% cheaper than evening flights, on average. The most expensive time of day to fly to the Cayman Islands is generally in the evening, which is peak travel time and where the average cost of a ticket is $806.

Reviews of the top airline flying from Santa Ana to the Cayman Islands

 
Need help choosing which airline to fly with from Santa Ana to the Cayman Islands? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11033 reviews
6.9Entertainment
7.5Boarding
8.0Crew
6.4Food
7.2Comfort
Airline reviews

The flight was flawless and we even arrived between 20 and 25 minutes early!

10.0 ExcellentLisa, Oct 2025LAX - CLT
Read more American Airlines reviews

The flight was flawless and we even arrived between 20 and 25 minutes early!

Always seated jammed in rear of aircraft Admirals Club food at DFW terminal D was absolute worst food experience and I pay $600/year to eat this dried out junk

Mostly good. Flight was crowded but Airline personnel were very friendly & accommodating. It would be good to have savory snacks rather than just sweet Biscoff cookies.

It was a red eye flight, so no meals were provided, but it was fine with snacks. The seats felt cramped and almost too narrow.

Very crowded flight but what can you expect these days?? Crew was accommodating.

The seats in economy were appeared to be quite thin and lack sufficient cushioning to be comfortable. Perhaps it was my seating position but the plane seemed notably load.

The entertainment package was vast and the selections were very current. Keep updating it was great.

The seat was so hard my tailbone was aching The crew was kind of a b**** because I made a joke that I didn't care if they close the door I total c*** when she was trying to f****** act like she was mad at me because I said that The flight was bumpy. Sure you didnt have control over that.

4 hours late, including over +1 hour waiting in plane to take off. Baggage left behind too.

While waiting to claim my checked luggage, I discovered the airline had lost it. After a long wait and inquiries, I discovered it was on another flight. Fortunately, the airline finally sent my luggage home.

Everything you need to know for your flight from Santa Ana to the Cayman Islands

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