$378 Find Cheap Flights from Santa Ana to the Cayman Islands

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to the Cayman Islands departing on 12/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Santa Ana to the Cayman Islands

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
George Town
George Town2 stops$597
George Town
George Town2 stops$597

Book Cheap Santa Ana to the Cayman Islands Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to the Cayman Islands that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to the Cayman Islands

Thu, Oct 30 - Thu, Nov 6
Multiple Airlines Logo
12:25 pm - 11:25 amSNA-GCM
21h 00m2 stops
Multiple Airlines Logo
1:30 pm - 8:59 pmGCM-SNA
34h 29m3 stops
$597Multiple Airlines
Find Deal
Thu, Oct 30 - Thu, Nov 6
United Airlines Logo
6:25 pm - 3:30 pmSNA-GCM
19h 05m2 stops
United Airlines Logo
5:45 pm - 9:23 amGCM-SNA
18h 38m2 stops
$660United Airlines
Find Deal
Thu, Oct 30 - Thu, Nov 6
United Airlines Logo
3:14 pm - 3:30 pmSNA-GCM
22h 16m1 stop
United Airlines Logo
5:45 pm - 9:23 amGCM-SNA
18h 38m2 stops
$675United Airlines
Find Deal
Thu, Oct 30 - Thu, Nov 6
Multiple Airlines Logo
8:09 pm - 9:15 pmSNA-GCM
23h 06m3 stops
Multiple Airlines Logo
1:30 pm - 8:59 pmGCM-SNA
34h 29m3 stops
$676Multiple Airlines
Find Deal
Fri, Nov 7 - Sat, Nov 15
United Airlines Logo
6:41 pm - 4:20 pmSNA-GCM
18h 39m2 stops
United Airlines Logo
2:50 pm - 8:54 amGCM-SNA
21h 04m2 stops
$770United Airlines
Find Deal
Thu, Oct 30 - Thu, Nov 6
Delta Logo
9:20 pm - 11:41 amSNA-GCM
12h 21m1 stop
Delta Logo
2:00 pm - 10:28 pmGCM-SNA
11h 28m1 stop
$806Delta
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Mon, Dec 22 - Mon, Dec 29
Delta Logo
7:15 pm - 12:37 pmSNA-GCM
14h 22m2 stops
Delta Logo
3:42 pm - 10:25 pmGCM-SNA
9h 43m1 stop
$810Delta
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Sun, Nov 9 - Sun, Nov 16
WestJet Logo
2:15 pm - 1:44 pmSNA-GCM
20h 29m2 stops
WestJet Logo
2:50 pm - 1:25 pmGCM-SNA
49h 35m2 stops
$1,090WestJet
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Sat, Dec 20 - Sun, Dec 28
WestJet Logo
2:15 pm - 1:44 pmSNA-GCM
44h 29m2 stops
WestJet Logo
2:50 pm - 1:25 pmGCM-SNA
49h 35m2 stops
$1,489WestJet
Find Deal
Tue, Mar 3 - Wed, Mar 4
American Airlines Logo
8:28 am - 1:50 pmSNA-GCM
26h 22m1 stop
American Airlines Logo
4:35 pm - 10:13 pmGCM-SNA
8h 38m1 stop
$7,299American Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Santa Ana to the Cayman Islands flights

Get data-powered insights and trends into flights from Santa Ana to the Cayman Islands to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Santa Ana to the Cayman Islands?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Santa Ana to the Cayman Islands were found on United Airlines ($660) and Delta ($806).

Good to know

Cheapest flight$378
Flight from John Wayne (Santa Ana) to George Town

FAQs - booking Cayman Islands flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to the Cayman Islands?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to the Cayman Islands.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to the Cayman Islands?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to the Cayman Islands is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to the Cayman Islands?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to the Cayman Islands with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to the Cayman Islands?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to the Cayman Islands up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to the Cayman Islands?

    The cheapest time of day to fly to the Cayman Islands is generally in the morning, when round-trip flights cost $601 on average. Morning departures are around 25% cheaper than evening flights, on average. The most expensive time of day to fly to the Cayman Islands is generally in the evening, which is peak travel time and where the average cost of a ticket is $806.

Reviews of the top airline flying from Santa Ana to the Cayman Islands

 
Need help choosing which airline to fly with from Santa Ana to the Cayman Islands? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
7.5Boarding
6.4Food
7.2Comfort
8.0Crew
6.9Entertainment
Airline reviews

The entertainment package was vast and the selections were very current. Keep updating it was great.

8.0 ExcellentAnonymous, Aug 2025SAN - DFW
Read more American Airlines reviews

The entertainment package was vast and the selections were very current. Keep updating it was great.

The seat was so hard my tailbone was aching The crew was kind of a b**** because I made a joke that I didn't care if they close the door I total c*** when she was trying to f****** act like she was mad at me because I said that The flight was bumpy. Sure you didnt have control over that.

4 hours late, including over +1 hour waiting in plane to take off. Baggage left behind too.

While waiting to claim my checked luggage, I discovered the airline had lost it. After a long wait and inquiries, I discovered it was on another flight. Fortunately, the airline finally sent my luggage home.

Was not able to watch most shows on the entertainment site. They would not load

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

Delayed flight, so I switched fights to SFO to Phoenix , Phoenix to DSM. Excellent service through American Airlines

AA re-routed flight from HNL to LAX due to delay. My group of 3 with reserved seats in row 9 was broken up, with one assigned to a middle seat, another in the last row of the plane. Not happy. No explanation to the delay. No apologies. No compensation. Would have been nice to be offered an Admiral Club admission or a voucher for the extra 3 hours of layover in LAX. Could not hear the boarding gate announcements in LAX. Adjacent gate was boarding at the same time. Loud speakers were competing against each other. Barely made my boarding group.

Almost a 6 hour flight and the only food option is a cheese plate… and chips. Also how is it there are no options for texting on American. I’ll be going back to delta and united.

Bad food, small seats that didn’t recline. I thought I was buying a quantas ticket so I feel like I got scammed

Everything you need to know for your flight from Santa Ana to the Cayman Islands

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