$234 Find Cheap Flights from Santa Ana to Italy

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Italy departing on 3/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Santa Ana to Italy

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Florence
Florence2 stops$465
Naples
Naples2 stops$439
Palermo
Palermo2 stops$715
Catania
Catania2 stops$508
Bologna
Bologna2 stops$436
Pisa
Pisa2 stops$2,977
Turin
Turin2 stops$548
Genoa
Genoa2 stops$605
Verona
Verona2 stops$549
Florence
Florence2 stops$465
Naples
Naples2 stops$439
Palermo
Palermo2 stops$715
Catania
Catania2 stops$508
Bologna
Bologna2 stops$436
Pisa
Pisa2 stops$2,977
Turin
Turin2 stops$548
Genoa
Genoa2 stops$605
Verona
Verona2 stops$549

Book Cheap Santa Ana to Italy Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Italy that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Italy

Wed, Jan 14 - Tue, Jan 27
British Airways Logo
8:05 am - 11:40 amSNA-BLQ
18h 35m2 stops
British Airways Logo
7:20 am - 10:01 pmBLQ-SNA
23h 41m2 stops
$436British Airways
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Wed, Feb 18 - Tue, Feb 24
British Airways Logo
4:35 pm - 3:35 pmSNA-NAP
38h 00m2 stops
British Airways Logo
12:40 pm - 10:19 pmNAP-SNA
42h 39m2 stops
$439British Airways
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Thu, Jan 22 - Wed, Feb 4
American Airlines Logo
9:30 am - 11:45 amSNA-MXP
17h 15m2 stops
American Airlines Logo
10:25 am - 10:01 pmMXP-SNA
20h 36m2 stops
$453American Airlines
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Thu, Feb 19 - Thu, Feb 26
Multiple Airlines Logo
6:45 am - 8:05 amSNA-MXP
16h 20m2 stops
Multiple Airlines Logo
10:25 am - 9:54 pmMXP-SNA
20h 29m2 stops
$456Multiple Airlines
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Tue, Feb 24 - Tue, Mar 10
Delta Logo
6:45 am - 9:45 amSNA-FCO
18h 00m2 stops
Delta Logo
8:20 am - 9:59 pmFCO-SNA
21h 39m2 stops
$461Delta
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Tue, Mar 3 - Thu, Mar 12
Multiple Airlines Logo
6:45 am - 5:55 pmSNA-FCO
26h 10m2 stops
Multiple Airlines Logo
11:35 am - 10:47 pmFCO-SNA
19h 12m1 stop
$464Multiple Airlines
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Wed, Jan 14 - Wed, Jan 21
United Airlines Logo
7:00 am - 9:55 amSNA-MXP
17h 55m2 stops
United Airlines Logo
1:05 pm - 8:17 pmMXP-SNA
40h 12m2 stops
$467United Airlines
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Thu, Jan 22 - Wed, Feb 4
American Airlines Logo
9:30 am - 11:30 amSNA-LIN
17h 00m2 stops
American Airlines Logo
7:35 am - 8:02 pmLIN-SNA
21h 27m2 stops
$474American Airlines
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Wed, Jan 28 - Sun, Feb 1
Delta Logo
6:45 am - 11:20 amSNA-VCE
19h 35m2 stops
Delta Logo
12:20 pm - 10:18 pmVCE-SNA
42h 58m2 stops
$477Delta
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Wed, Jan 14 - Wed, Jan 21
United Airlines Logo
7:50 pm - 12:40 pmSNA-BLQ
31h 50m2 stops
United Airlines Logo
6:00 am - 6:41 pmBLQ-SNA
21h 41m2 stops
$497United Airlines
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Booking Insights

KAYAK's insights & trends for Santa Ana to Italy flights

Get data-powered insights and trends into flights from Santa Ana to Italy to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Santa Ana to Italy?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Ana to Italy, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santa Ana to Italy is November, when tickets cost $561 (return) on average. On the other hand, the most expensive months are December and October, when the average cost of round-trip tickets is $1,440 and $926 respectively.

Good to know

Low seasonJanuary
Cheapest flight$222
Best time to beat the crowds with an average 39% drop in price.
Most popular time to fly and prices are also 21% lower on average.
Flight from John Wayne (Santa Ana) to Venice

FAQs - booking Italy flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Italy?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Italy.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Italy?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Italy is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Italy?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Italy with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Italy?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Italy up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Italy?

    The cheapest time of day to fly to Italy is generally in the evening, when round-trip flights cost $920 on average. Morning departures are around 56% more expensive than evening flights, on average. The most expensive time of day to fly to Italy is generally in the morning, which is peak travel time and where the average cost of a ticket is $1,437.

Reviews of the top 3 airlines serving from Santa Ana to Italy

 
Need help choosing which airline to fly with from Santa Ana to Italy? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8010 reviews
8.5Crew
7.9Comfort
7.9Entertainment
7.3Food
8.1Boarding
Airline reviews

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

8.0 ExcellentDeborah, Nov 2025LAX - RDU
Read more Delta reviews

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

The flight used a B767 with a very old interior from before 2014. The entertainment system did not work at all during the flight despite attempts to reset the system. It was like they flew this route just to be competitive.

Delayed flight (1hour) plus a long layover after an overnight flight with no backup plane available.

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

My husband upgraded our seats and I don't know if it was due to the type of planet was or if they didn't upgrade our seats. We were supposed to be in I believe comfort seats and they were just as tight as any other seat- no leg room and we are very tall people but at least it wasn't extremely cold. My husband did put in a complaint about our seating because he paid extra and if we would have known that the space and the tightness would have been the same, we just would have gotten the emergency row emergency row seats that we normally get. We love Delta but both our flights coming home we're not good. Oh I forgot to mention that on our flight to Hawaii our luggage wheels got broke and we had to purse new luggage on vacation then we never had this problem so we didn't know protocol and reported it after we got home only for them to tell is we only had 24hrs to report the damage. Not sure what was going on with Delta this vacation trip.

Crew was excellent. Comfort seats not as nice as other kinds of planes.

It was a great flight and the stewards and stewardess were all kind and accommodating!! The seats were comfortable and entertainment screen excellent!

There are 4 flights in consecutive gates with about the same departure time. Two flights were boarding at the same time. One was delayed or boarding would be happening at the same time. I am not sure what Delta and LAX need to do to have a better layout at the end of Terminal 2

from SFO-> FRA flight, AVML meal was significantly less compared to regular meal, especially no Desert, no Bread, no sides.

This was an older airplane. The cabin was constantly warm to hot throughout the 10 hour flight and there were no vents to personalize air flow. Also since it was an older plane, the material and comfort of the chairs were very uncomfortable. I left my flight with major soreness on my tailbone.

Older aircraft, no meal, only food was for purchase. Not impressed United.

Not pleasant trip cross country when the entertainment and WiFi system not working. No entertainment for entirety of route. Staff was rather nonchalant in that they dismissed the problem due to age of plane. It would have been nice to know this up front so I could have come prepared to read or download movies before boarding Coincidentally or not, there was a similar issue with the entertainment system on my previous flight I took on my fist leg of the trip. There are no seat TVs, so you must rely on the app when it works. United can do better. Also, what use it it to pay for boarding group 2 when half of the passengers are in the same line as you?

My experience on this United Airlines flight was highly uncomfortable, primarily due to two issues: Cabin Temperature: The temperature on the Boeing 737 MAX 8 was unacceptably high, feeling consistently around 80 degrees throughout the flight. This made sleeping impossible and significantly detracted from the experience. Seating Arrangement: Being stuck in a middle seat for a six-and-a-half-hour overnight flight compounded the discomfort. Moving forward, I will always purchase a seat assignment to avoid this situation.

Premium Plus is a really good idea for longer flights

Same as last comment. Food sucks. Quality. Not surprising most people have no clue about nourishment Clearly

The flight attendants were great, I joked with one I can’t remember her name, a blond, really sweet. I thought it was run well very professional. This was great i survived Spirit, I know for which I speak.

We were in business class. the angled seats in that class do not have a real window view & the placement of the controls are bad. But we knew that. But the food options were mediocre. The taste was fine, but the size was for a child. It’s just really feels like United is skimping on everything. Even when we were in the Polaris lounge they did not have diet sodas. They said they were out no Coke zero no Diet Coke, etc. I do not think the portion of nuts they serve on the plane could get any smaller. Really a minimal service and offer for what you’re paying for in business.

I was in first class. The outlets at my seat did not work. The plane was shabby and run down. I had prepurchsed a day subscription for internet that was not redeemable. I had to repurchase the internet for my flight and then it didn’t work anyway. Quite disappointed in what was supposed to be the launch of a great vacation.

Wonderful! Everyone very helpful and kind. Returning flight was cancelled but rebooking was easy.

Pretty normal flight was delayed due to traffic could have missed connecting flight to Venice but crew kept us well informed so we made it

Flight was on time and pretty standard. No Hiccups. I have no complaints, which is a lot to say about a 12 hour flight.

-The seats could be roomier -The entertainment in English could be more current! The moves were very old!!! -They served too many carbs! What happened to fruit and yogurt!!!!

We upgraded to premium economy and it made a difference in a 12 hr flight. I didn’t like that we had to deplane in the tarmac with our carryon luggage. Other than that, it was ok.

Everything was much better than I had expected, since I hadn’t heard of your airline before. I hope to take advantage of your excellent service again.

Staff were nice, we left on time and arrived early, food was good. Unfortunately, they lost one of our bags and have been unable to find it. So we are in Italy for a week for my husband‘s birthday and he does not have any of his clothing.

They gave us sandwiches as a meal twice. Snacks mid flight with cookies and a tuna panini. Then just the same tuna panini for dinner. That was it.

Top notch re cleanliness, comfort, operational. Attendants attentive, cheerful, courteous and professional. An unusually high-grade experience all around.

The staff was very good, the only thing was the air conditioning wasn't working during the boarding process so it was very hot inside the plane until we got airborne. The food wasn't great, the chicken was dry and hard to cut, the ravioli was ok and the little pizza pocket thing was pretty bad. Other than that is was a good flight all around

Everything you need to know for your flight from Santa Ana to Italy

Information on your arrival and departure airports