$298 Find Cheap Flights from Santa Ana to Italy

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Italy departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Cheap Flights from Santa Ana to Italy

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Florence
Florence2 stops$736
Naples
Naples2 stops$765
Palermo
Palermo2 stops$955
Catania
Catania2 stops$1,129
Bologna
Bologna2 stops$804
Pisa
Pisa2 stops$970
Turin
Turin2 stops$1,165
Genoa
Genoa2 stops$1,098
Verona
Verona2 stops$947
Florence
Florence2 stops$736
Naples
Naples2 stops$765
Palermo
Palermo2 stops$955
Catania
Catania2 stops$1,129
Bologna
Bologna2 stops$804
Pisa
Pisa2 stops$970
Turin
Turin2 stops$1,165
Genoa
Genoa2 stops$1,098
Verona
Verona2 stops$947

Book Cheap Santa Ana to Italy Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Italy that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Italy

Tue, Apr 21 - Tue, Apr 28
United Airlines Logo
2:40 pm - 1:20 pm
SNA
-
MXP
13h 40m
1 stop
United Airlines Logo
12:20 pm - 10:35 pm
MXP
-
SNA
43h 15m
2 stops
$672United Airlines
Tue, Aug 4 - Wed, Aug 26
British Airways Logo
7:45 am - 9:10 am
SNA
-
FCO
16h 25m
1 stop
British Airways Logo
1:10 pm - 9:51 pm
FCO
-
SNA
17h 41m
1 stop
$672British Airways
Tue, Apr 21 - Thu, Apr 30
Air Canada Logo
12:25 pm - 4:40 pm
SNA
-
MXP
19h 15m
2 stops
Air Canada Logo
12:20 pm - 5:31 pm
MXP
-
SNA
38h 11m
2 stops
$674Air Canada
Sun, Aug 16 - Fri, Aug 28
Delta Logo
7:45 am - 10:10 am
SNA
-
FCO
17h 25m
1 stop
Delta Logo
6:30 am - 4:18 pm
FCO
-
SNA
18h 48m
2 stops
$676Delta
Tue, Apr 21 - Tue, Apr 28
Air Canada Logo
12:25 pm - 4:40 pm
SNA
-
MXP
19h 15m
2 stops
Air Canada Logo
12:20 pm - 5:27 pm
MXP
-
SNA
38h 07m
3 stops
$679Air Canada
Tue, Aug 18 - Fri, Aug 28
Delta Logo
11:00 am - 7:05 pm
SNA
-
FCO
23h 05m
2 stops
Delta Logo
6:30 am - 4:18 pm
FCO
-
SNA
18h 48m
2 stops
$680Delta
Tue, May 5 - Tue, May 12
Multiple Airlines Logo
11:54 am - 1:55 pm
SNA
-
LIN
17h 01m
2 stops
Multiple Airlines Logo
6:40 am - 4:41 pm
LIN
-
SNA
19h 01m
2 stops
$733Multiple Airlines
Tue, Apr 21 - Wed, Apr 29
Multiple Airlines Logo
4:15 pm - 4:35 pm
SNA
-
VCE
15h 20m
2 stops
Multiple Airlines Logo
11:05 am - 10:12 pm
VCE
-
SNA
20h 07m
1 stop
$831Multiple Airlines
Thu, Apr 9 - Thu, Apr 23
Lufthansa Logo
1:21 pm - 11:40 pm
SNA
-
BLQ
25h 19m
2 stops
Lufthansa Logo
10:20 am - 8:47 pm
BLQ
-
SNA
19h 27m
2 stops
$850Lufthansa
Sun, Sep 6 - Thu, Sep 10
Lufthansa Logo
11:30 am - 5:20 pm
SNA
-
PMO
20h 50m
2 stops
Lufthansa Logo
11:50 am - 8:40 pm
PMO
-
SNA
41h 50m
2 stops
$955Lufthansa
Booking Insights

KAYAK's insights & trends for Santa Ana to Italy flights

Get data-powered insights and trends into flights from Santa Ana to Italy to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Santa Ana to Italy?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Ana to Italy, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santa Ana to Italy is November, when tickets cost $509 (return) on average. On the other hand, the most expensive months are December and July, when the average cost of round-trip tickets is $1,440 and $928 respectively.

Good to know

Low seasonNovember
Cheapest flight$298
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly and prices are also 24% lower on average.
Flight from John Wayne (Santa Ana) to Venice

FAQs - booking Italy flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Italy?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Italy.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Italy?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Italy is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Italy?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Italy with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Italy?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Italy up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Santa Ana to Italy

 
Need help choosing which airline to fly with from Santa Ana to Italy? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8318 reviews
7.9Comfort
7.8Entertainment
8.1Boarding
7.2Food
8.5Crew
Airline reviews

My recent experience was excellent on Delta! I flew with Delta Comfort and I was really comfortable in my seat. I enjoyed the in-flight service. The flight attendants were so friendly and hospitable. I love the snack on the flight as well. This was my first time flying on Delta and I will definitely consider flying with them again.

10.0 ExcellentShirley, Mar 2026
LAX - ATL
Read more Delta reviews

My recent experience was excellent on Delta! I flew with Delta Comfort and I was really comfortable in my seat. I enjoyed the in-flight service. The flight attendants were so friendly and hospitable. I love the snack on the flight as well. This was my first time flying on Delta and I will definitely consider flying with them again.

My flight was canceled on Sunday. Rebooking took three hours. Had to pay for accommodations another night. New flight was delayed for 5 hours, all that was sent was a 12 dollar food voucher, which doesn’t tell you how to use it. Then when we landed we had to sit on the plane for an hour before we could get off.

I was in first class and literally the men behind me were so aggressively loud I moved myself to economy. This has become so common on Delta - people using audio without headphones, and men on 12am / late night flights drinking and yelling to talk to each other which prevents anyone around them from resting. Pretty crazy to have to move from first to economy (poorer service, less comfort...). Wild wild. Looking into other airlines.

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

The crew, and fellow passengers, were super gracious and kind. There seemed to be plenty of bin space even though the plane was full. It’s nice to get a glass of wine with dinner in Premiere seating, and there was a lot of food.

Everything I mentioned earlier - the airbus was more comfortable indeed and the experience was further enhanced.

The plane was an older model, so it wasn’t as comfortable as others. The flight attendants were not helpful during onboarding. It was a full flight so there was chaos finding space for baggage.

Awesome! On time flight, early arrival, and a complimentary upgrade!

It was nt delta. It was aeromexo. Service was awful. They served a very small drink and NO snack for a 3hr and 35min flight. Then for the first 30 min of the flight is was talk and talk over head interruption the movie/ show i picked to watch.

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

My flight was canceled a few hours before boarding. I was rebooked on Copa airlines and missed an important meeting .

Business class seats felt very cramped compared to other airlines.

OK, we were delayed and had to de plane and reboard.

The 777’s economy seat’s legroom was more tolerable than expected. I appreciate the reclining mechanism which slides the seat forward to minimize cannibalizing the space behind. The food was terrible: very salty.

Seats are uncomfortable. This has been a trend in the industry for decades. Trying to fit more seats on each plane to increase profits at the expense of the passenger.

Staff were good. My seat was in need of repair, but for a short flight was not problematic. Usual basic snack and drink setup that you'll find on any US carrier. Over, a decent, basic flight.

Complimentary light meal would be appreciated. But great flight crew service on all legs

Flight delayed for more than 16 hrs and no effort was spent to provide an alternate

We had turbulence ever 1/2 hr or so and the captains announcements were SOOOO LOUD

Women boarding passengers at the gate was absolutely rude and disrespectful of passengers. The flight attendant was absolutely delightful! Smiling and connected with the passengers. So happy. The seats are cramped and uncomfortable but I guess that’s just the way it is Communication regarding flight was excellent

Lufthansa cancelled our flight from Los Angeles to Naples Italy on March 10 for scheduled flight on March 12 Very stressful experience trying to arrange alternatives. Will never fly again with Lufthansa

Service and food were excellent. Incredibly friendly and competent staff. Flight was delayed over and hour and I had to run between terminals to get my connecting flight.

Late flight Delays Poor service Poor staff Worst airline ever

Lufthansa still has a good level of quality compared to US airlines, especially with respect to (1) food quality - actually tasty, (2) good French red wine - free, (3) good movie selection. Also my ticket price includes 1 free check-in luggage, while some other budget airlines sneak in an extra $150 for a checkin.

The food could be better, more snacks. And have some plugs to chargue the phone.

Everything was really great just The aircraft was too old and sounded it will break during takeoff

Extremely pleased with the crew. Best flight attendants ever! Very friendly, genuinely caring and attentive.

Best flight attendants ever! Very customer and service oriented, courteous, professional and helpful.

Cheapest airlines I have ever been on. I got downgraded and never got on united. I got rerouted through Vancouver onto jetwesf

Very small and uncomfortable seats, Hard to hear entertainment system sound. Horrible food. Staff doesn't care much about the passengers. 2nd time they didn't give me my vegetarian meal. They asked me regular food with meat. The airline and staff was from United airlines.

Everything you need to know for your flight from Santa Ana to Italy

Information on your arrival and departure airports