$214 Find Cheap Flights from Santa Ana to Italy

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Italy departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Santa Ana to Italy

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Florence
Florence2 stops$538
Naples
Naples2 stops$617
Palermo
Palermo2 stops$744
Catania
Catania2 stops$870
Bologna
Bologna2 stops$782
Pisa
Pisa2 stops$620
Turin
Turin2 stops$965
Genoa
Genoa2 stops$1,254
Verona
Verona2 stops$752
Florence
Florence2 stops$538
Naples
Naples2 stops$617
Palermo
Palermo2 stops$744
Catania
Catania2 stops$870
Bologna
Bologna2 stops$782
Pisa
Pisa2 stops$620
Turin
Turin2 stops$965
Genoa
Genoa2 stops$1,254
Verona
Verona2 stops$752

Book Cheap Santa Ana to Italy Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Italy that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Italy

Wed, Mar 11 - Thu, Mar 19
Delta Logo
7:30 am - 5:25 pm
SNA
-
MXP
25h 55m
2 stops
Delta Logo
6:55 am - 9:55 pm
MXP
-
SNA
23h 00m
2 stops
$507Delta
Sat, Aug 1 - Wed, Aug 19
United Airlines Logo
6:26 pm - 12:20 pm
SNA
-
FCO
32h 54m
1 stop
United Airlines Logo
6:50 am - 8:51 pm
FCO
-
SNA
23h 01m
2 stops
$517United Airlines
Wed, Mar 18 - Wed, Apr 1
United Airlines Logo
7:00 am - 7:30 am
SNA
-
MXP
16h 30m
2 stops
United Airlines Logo
12:20 pm - 9:44 am
MXP
-
SNA
30h 24m
2 stops
$520United Airlines
Mon, Aug 3 - Wed, Aug 19
Air Canada Logo
9:14 pm - 10:20 am
SNA
-
FCO
28h 06m
2 stops
Air Canada Logo
11:30 am - 12:23 pm
FCO
-
SNA
33h 53m
2 stops
$530Air Canada
Sun, Aug 2 - Thu, Aug 20
Delta Logo
1:55 pm - 5:30 pm
SNA
-
FCO
18h 35m
2 stops
Delta Logo
1:10 pm - 10:24 pm
FCO
-
SNA
18h 14m
1 stop
$532Delta
Tue, Apr 14 - Wed, Apr 22
British Airways Logo
7:45 am - 9:10 am
SNA
-
FCO
16h 25m
1 stop
British Airways Logo
1:10 pm - 10:45 pm
FCO
-
SNA
18h 35m
1 stop
$533British Airways
Sat, Apr 11 - Thu, Apr 23
Air Canada Logo
1:21 pm - 10:20 am
SNA
-
MXP
59h 59m
3 stops
Air Canada Logo
12:20 pm - 5:27 pm
MXP
-
SNA
38h 07m
2 stops
$536Air Canada
Wed, Aug 12 - Wed, Aug 26
British Airways Logo
4:30 pm - 10:20 pm
SNA
-
FLR
20h 50m
2 stops
British Airways Logo
7:05 am - 7:58 pm
FLR
-
SNA
21h 53m
2 stops
$538British Airways
Mon, Mar 30 - Tue, Apr 7
Lufthansa Logo
11:10 am - 1:55 pm
SNA
-
VRN
17h 45m
2 stops
Lufthansa Logo
6:30 am - 8:55 pm
VRN
-
SNA
23h 25m
2 stops
$752Lufthansa
Thu, Mar 19 - Tue, Apr 7
Lufthansa Logo
1:27 pm - 12:35 pm
SNA
-
VRN
15h 08m
2 stops
Lufthansa Logo
6:30 am - 6:31 pm
VRN
-
SNA
21h 01m
2 stops
$1,057Lufthansa
Booking Insights

KAYAK's insights & trends for Santa Ana to Italy flights

Get data-powered insights and trends into flights from Santa Ana to Italy to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Santa Ana to Italy?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Ana to Italy, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santa Ana to Italy is November, when tickets cost $509 (return) on average. On the other hand, the most expensive months are December and July, when the average cost of round-trip tickets is $1,440 and $928 respectively.

Good to know

Low seasonJanuary
Cheapest flight$214
Best time to beat the crowds with an average 36% drop in price.
Most popular time to fly with an average 5% increase in price.
Flight from John Wayne (Santa Ana) to Venice

FAQs - booking Italy flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Italy?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Italy.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Italy?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Italy is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Italy?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Italy with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Italy?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Italy up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Santa Ana to Italy

 
Need help choosing which airline to fly with from Santa Ana to Italy? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8246 reviews
7.9Comfort
8.5Crew
8.1Boarding
7.2Food
7.8Entertainment
Airline reviews

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

4.0 OkayJahmes, Feb 2026
LAX - MCO
Read more Delta reviews

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

The crew, and fellow passengers, were super gracious and kind. There seemed to be plenty of bin space even though the plane was full. It’s nice to get a glass of wine with dinner in Premiere seating, and there was a lot of food.

Everything I mentioned earlier - the airbus was more comfortable indeed and the experience was further enhanced.

The plane was an older model, so it wasn’t as comfortable as others. The flight attendants were not helpful during onboarding. It was a full flight so there was chaos finding space for baggage.

Awesome! On time flight, early arrival, and a complimentary upgrade!

It was nt delta. It was aeromexo. Service was awful. They served a very small drink and NO snack for a 3hr and 35min flight. Then for the first 30 min of the flight is was talk and talk over head interruption the movie/ show i picked to watch.

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

Delta’s staff is unmatched. From the gate agents, to the pilots, to the flight attendants… all top of the industry.

The flight was delayed for about 2 hrs. Other than it, it was good.

I am extremely disappointed that delta internal pilot manuals now refer to the Gulf of Mexico as the “gulf of America”. You can bow down to the Orange turd on your own. I will never fly delta again

Flight delayed for more than 16 hrs and no effort was spent to provide an alternate

We had turbulence ever 1/2 hr or so and the captains announcements were SOOOO LOUD

Women boarding passengers at the gate was absolutely rude and disrespectful of passengers. The flight attendant was absolutely delightful! Smiling and connected with the passengers. So happy. The seats are cramped and uncomfortable but I guess that’s just the way it is Communication regarding flight was excellent

it was a very short flight so my expectations were low.

Entertainment kept turning itself off. Gave up on watching a movie.

Very disappointing given gate agent behavior. Filed a formal complaint with United.

Crew was great (professional, attentive, prompt). Snacks for 4 hrs flight is deplorable.

Flight delayed. WiFi connectivity very poor if not existant. Last minute arrival forced me to run to catch my connection.

Terrible. No customer service, no food, no drinks on a 6 hour premier economy booking.

Check-in and in-flight staff were better than average. The seat was a fair size but too hard and not enough padding. The cushion/pillow provided is poor (thin and seems to be disposable ,it provides no effective cushioning or support). Food was OK-ish but no choice of inflight snacks and no easy place to get drinks other than water (I could ask for juice by intruding into the staff area at the back of the plane) Entertainment was very good actually. Overall better than I expected from a US-based airline (sorry!) but compared to ANA or Singapore it was so-so. (I live in Japan so they are my comparative airlines)

Service and food were excellent. Incredibly friendly and competent staff. Flight was delayed over and hour and I had to run between terminals to get my connecting flight.

Late flight Delays Poor service Poor staff Worst airline ever

Lufthansa still has a good level of quality compared to US airlines, especially with respect to (1) food quality - actually tasty, (2) good French red wine - free, (3) good movie selection. Also my ticket price includes 1 free check-in luggage, while some other budget airlines sneak in an extra $150 for a checkin.

The food could be better, more snacks. And have some plugs to chargue the phone.

Everything was really great just The aircraft was too old and sounded it will break during takeoff

Extremely pleased with the crew. Best flight attendants ever! Very friendly, genuinely caring and attentive.

Best flight attendants ever! Very customer and service oriented, courteous, professional and helpful.

Cheapest airlines I have ever been on. I got downgraded and never got on united. I got rerouted through Vancouver onto jetwesf

Very small and uncomfortable seats, Hard to hear entertainment system sound. Horrible food. Staff doesn't care much about the passengers. 2nd time they didn't give me my vegetarian meal. They asked me regular food with meat. The airline and staff was from United airlines.

Checkin took along timen only.few angents available at.checkin desk. Customer support over phone no existence

They lost my checked in bag and have not helped me.

First, ITA lost my bag and the baggage team showed no regard in trying to find it. Second, I had paid for priority boarding as part of a first class ticket and instead they disregarded boarding groups and we all boarded at the same time. Third, wasn't allowed to select my seat in advance even with a first class ticket. When I was assigned bulkhead, I was told I would need to pay to change my seat. Overall, very disappointing experience.

The seats needs to be spruced up , for a long flight very uncomfortable , cushions are worn out but everything else is very good , crew is great.

I guess that was fine with ITA but the Rome airport is so difficult to navigate with so many checkpoints getting new tickets from what was originally given to me

I did not leave to Italy yet. We had technical problems on flight from SF to Maimi and had to land in Denver and wait for another plane to take us to Miami, so I missed my plane to Italy. I am still waiting for the Agency to fix my flight till today the haven’t done anything and I am paying for my Hotel stay. Everyday they are promising to fix my flight, they are not doing so and they are not even looking for another solution

My seat was broken and ducted taped and my monitor did not work the entire time over 8 hrs sitting. And I had no books or anything with me

my flight from Rome to Boston was on a very old plane. My video and audio did not work.

Good with timing of flights. The crew was exceptionally unfriendly. I heard more than one person say this. And even with the aisle, it seemed more uncomfortable than usual. The movie selection was old and poor, but the dinner was great - the lasagna and tiramisu.

The check in process is chaotic. It says partially checked-in. Never heard of such a thing. Then lost our reserved seats when we finally checked in at the airport. The seats don’t recline. Then we had to get mew boarding passes at the connection. Last, my companion lost her baggage and up to now there’s no update. We’re already half-way through our vacation and still no news what happened to the luggage.

Wonderful! Everyone very helpful and kind. Returning flight was cancelled but rebooking was easy.

Everything you need to know for your flight from Santa Ana to Italy

Information on your arrival and departure airports