$250 Find Cheap Flights from Santa Ana to Italy

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Italy departing on 11/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Santa Ana to Italy

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Florence
Florence2 stops$547
Naples
Naples2 stops$500
Palermo
Palermo2 stops$949
Catania
Catania2 stops$698
Bologna
Bologna2 stops$630
Pisa
Pisa2 stops$800
Turin
Turin2 stops$631
Genoa
Genoa2 stops$575
Verona
Verona2 stops$678
Florence
Florence2 stops$547
Naples
Naples2 stops$500
Palermo
Palermo2 stops$949
Catania
Catania2 stops$698
Bologna
Bologna2 stops$630
Pisa
Pisa2 stops$800
Turin
Turin2 stops$631
Genoa
Genoa2 stops$575
Verona
Verona2 stops$678

Book Cheap Santa Ana to Italy Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Italy that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Italy

Wed, Feb 18 - Tue, Feb 24
Delta Logo
6:45 am - 11:25 amSNA-VCE
19h 40m2 stops
Delta Logo
1:20 pm - 10:51 amVCE-SNA
30h 31m2 stops
$395Delta
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Wed, Feb 18 - Tue, Feb 24
Delta Logo
7:15 am - 5:20 pmSNA-VCE
25h 05m2 stops
Delta Logo
1:20 pm - 11:34 amVCE-SNA
31h 14m2 stops
$414Delta
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Wed, Dec 3 - Wed, Dec 10
KLM Logo
6:45 am - 7:55 amSNA-FCO
16h 10m1 stop
KLM Logo
10:05 am - 10:20 pmFCO-SNA
21h 15m1 stop
$475KLM
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Wed, Feb 11 - Mon, Feb 16
British Airways Logo
8:05 am - 11:40 amSNA-BLQ
18h 35m2 stops
British Airways Logo
6:20 pm - 9:43 pmBLQ-SNA
36h 23m2 stops
$476British Airways
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Wed, Oct 29 - Tue, Nov 4
United Airlines Logo
7:15 am - 7:30 amSNA-MXP
16h 15m1 stop
United Airlines Logo
3:05 pm - 10:13 pmMXP-SNA
16h 08m1 stop
$491United Airlines
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Tue, Nov 4 - Tue, Nov 18
Lufthansa Logo
6:25 pm - 8:45 pmSNA-MXP
17h 20m2 stops
Lufthansa Logo
9:50 am - 5:48 pmMXP-SNA
16h 58m2 stops
$492Lufthansa
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Wed, Oct 29 - Tue, Nov 4
United Airlines Logo
2:07 pm - 1:05 pmSNA-MXP
14h 58m1 stop
United Airlines Logo
10:40 am - 8:32 pmMXP-SNA
18h 52m2 stops
$494United Airlines
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Thu, Nov 13 - Wed, Nov 19
KLM Logo
8:00 am - 3:50 pmSNA-NAP
22h 50m2 stops
KLM Logo
6:15 am - 10:19 pmNAP-SNA
25h 04m2 stops
$500KLM
Find Deal
Tue, Nov 4 - Tue, Nov 18
Lufthansa Logo
1:30 pm - 2:15 pmSNA-LIN
15h 45m2 stops
Lufthansa Logo
9:45 am - 5:48 pmLIN-SNA
17h 03m2 stops
$509Lufthansa
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Mon, Nov 24 - Tue, Dec 2
British Airways Logo
4:25 pm - 9:55 pmSNA-FCO
20h 30m2 stops
British Airways Logo
8:25 pm - 9:41 pmFCO-SNA
34h 16m2 stops
$530British Airways
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Booking Insights

KAYAK's insights & trends for Santa Ana to Italy flights

Get data-powered insights and trends into flights from Santa Ana to Italy to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Santa Ana to Italy?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Ana to Italy, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santa Ana to Italy is November, when tickets cost $561 (return) on average. On the other hand, the most expensive months are December and October, when the average cost of round-trip tickets is $967 and $926 respectively.

Good to know

Low seasonNovember
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 25% increase in price.

FAQs - booking Italy flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Italy?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Italy.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Italy?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Italy is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Italy?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Italy with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Italy?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Italy up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Italy?

    The cheapest time of day to fly to Italy is generally in the evening, when round-trip flights cost $920 on average. Morning departures are around 56% more expensive than evening flights, on average. The most expensive time of day to fly to Italy is generally in the morning, which is peak travel time and where the average cost of a ticket is $1,437.

Reviews of the top 4 airlines serving from Santa Ana to Italy

 
Need help choosing which airline to fly with from Santa Ana to Italy? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7979 reviews
7.3Food
8.2Boarding
7.9Entertainment
7.9Comfort
8.5Crew
Airline reviews

Delayed flight (1hour) plus a long layover after an overnight flight with no backup plane available.

6.0 GoodFernando, Oct 2025SAN - ATL
Read more Delta reviews

Delayed flight (1hour) plus a long layover after an overnight flight with no backup plane available.

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

My husband upgraded our seats and I don't know if it was due to the type of planet was or if they didn't upgrade our seats. We were supposed to be in I believe comfort seats and they were just as tight as any other seat- no leg room and we are very tall people but at least it wasn't extremely cold. My husband did put in a complaint about our seating because he paid extra and if we would have known that the space and the tightness would have been the same, we just would have gotten the emergency row emergency row seats that we normally get. We love Delta but both our flights coming home we're not good. Oh I forgot to mention that on our flight to Hawaii our luggage wheels got broke and we had to purse new luggage on vacation then we never had this problem so we didn't know protocol and reported it after we got home only for them to tell is we only had 24hrs to report the damage. Not sure what was going on with Delta this vacation trip.

Crew was excellent. Comfort seats not as nice as other kinds of planes.

It was a great flight and the stewards and stewardess were all kind and accommodating!! The seats were comfortable and entertainment screen excellent!

There are 4 flights in consecutive gates with about the same departure time. Two flights were boarding at the same time. One was delayed or boarding would be happening at the same time. I am not sure what Delta and LAX need to do to have a better layout at the end of Terminal 2

There was a security issue at the airport and we were unable to land. We circled endlessly and then landed at another airfield for fuel. We then circled the airport again, almost landed but didn’t fully touch down before circling again. I am thankful to the crew for keeping us safe- the issue was the airline and staff at the airport getting us seats on our connecting flights. That part was hours of searching for someone and getting in double my steps.

Most aspects were good however if they assign boarding zones they ought to enforce them or why bother? My luggage from SAN-JFK-MAD was lost in NY so I without my main bag for two days upon arrival in Spain. They were helpful in tracking it and eventually delivered it to my hotel. The flub was because of a delay upon arrival in NYC. I had booked 2 1/2 hours between flights but we had to hold on the taxiway for an hour after landing while waiting for a clear gate which likely caused the baggage error.

Excellent flight, the planes were newer, they did a nice job with boarding, great service overall.

It would be nice if was given wires ear buds. Overall was a good experience was able to sleep on the plane

We were in business class. the angled seats in that class do not have a real window view & the placement of the controls are bad. But we knew that. But the food options were mediocre. The taste was fine, but the size was for a child. It’s just really feels like United is skimping on everything. Even when we were in the Polaris lounge they did not have diet sodas. They said they were out no Coke zero no Diet Coke, etc. I do not think the portion of nuts they serve on the plane could get any smaller. Really a minimal service and offer for what you’re paying for in business.

I was in first class. The outlets at my seat did not work. The plane was shabby and run down. I had prepurchsed a day subscription for internet that was not redeemable. I had to repurchase the internet for my flight and then it didn’t work anyway. Quite disappointed in what was supposed to be the launch of a great vacation.

We had to deboard 2 times due to maintenance issues. They changed the plane, and then we got deviated to LAX due to maibtenance issues on the other plane, had to sleep at LAX and los a full day.

From the first moment you interact with United Airlines, you can expect nothing less but extreme frustration. The baggage handler at the bag drop seems completely unbothered by the presence of customers waiting in line. No help was extended to load the baggage whatsoever. And if any of your bags is overweight by 0.01 pound they will make you re-distribute everything in your suitcase just to play power trip. When it was time to board no help was extended to customers to locate their seats. Moreover. It was a chaotic mess at the gate when it was unclear who should board first and everyone just bunched up, trying to get on the plane. I am sure the crew was doing their best to perform their jobs while being paid their wages however it shouldn’t be that hard to smile once or twice when you’re in the business if serving customers. It is a shame for the United States of America to have a flagship carrier of such low caliber. Our flight was also delayed by about an hour and a half due to further delays prior to our inbound flight. Being someone who has travelled for both business and leisure in Asia, Europe, and South America I have never experienced such poor quality of service.

I understand stuff happens, but plane failures are likely due to lack of maintenance. Additionally, air conditioning wasn't working, no snack/drink service, no WiFi. Fortunately, the crew was communicative and light-hearted. United grabbed another plane and we were able to get to our destination.

The pilots were late and it made us 1 hour late. The meat was tough and bok choy was also tough.

Stuck on tarmac for two hours plus a 5.5 hour flight. Rude flight attendant. And no meals, not even for purchase!

I learned that seating towards the end of plane that a line forms for the restroom and people use your chair as a hand railing, bumping your seat consistently. I was seated in the aisle. I think that next time if I am towards the back row I would want to sit in the middle or window seat.

The best airline I have ever travel , really good customer service, attention and service !!

United sent me a mileage plus number last year but that number is invalid so I can’t use it to check into flights or collect mileage. There is human to speak about the problem, only computers who keep asking me if I am using the correct email. It’s so frustrating and I cannot resolve it.

Pretty normal flight was delayed due to traffic could have missed connecting flight to Venice but crew kept us well informed so we made it

Flight was on time and pretty standard. No Hiccups. I have no complaints, which is a lot to say about a 12 hour flight.

-The seats could be roomier -The entertainment in English could be more current! The moves were very old!!! -They served too many carbs! What happened to fruit and yogurt!!!!

We upgraded to premium economy and it made a difference in a 12 hr flight. I didn’t like that we had to deplane in the tarmac with our carryon luggage. Other than that, it was ok.

Everything was much better than I had expected, since I hadn’t heard of your airline before. I hope to take advantage of your excellent service again.

Staff were nice, we left on time and arrived early, food was good. Unfortunately, they lost one of our bags and have been unable to find it. So we are in Italy for a week for my husband‘s birthday and he does not have any of his clothing.

They gave us sandwiches as a meal twice. Snacks mid flight with cookies and a tuna panini. Then just the same tuna panini for dinner. That was it.

Top notch re cleanliness, comfort, operational. Attendants attentive, cheerful, courteous and professional. An unusually high-grade experience all around.

The staff was very good, the only thing was the air conditioning wasn't working during the boarding process so it was very hot inside the plane until we got airborne. The food wasn't great, the chicken was dry and hard to cut, the ravioli was ok and the little pizza pocket thing was pretty bad. Other than that is was a good flight all around

Better consideration for families traveling with a disabled person. They insisted each person hold their own boarding pass on their own devices and gave us a hard time accepting eight boarding passes on a single device.

Need to offer Better food from LAX to London Service from London to Delhi very delayed after take off.

Great crew and food and beverage. Seating tight but not the airline's fault. Will definitely fly BA in future!

Crying baby the ENTIRE flight. Not your fault, but I paid 2700 for a premium economy ticket and it wasn't worth it. should have just stuck with coach. flight attendants very mediocre - minimal effort. Plane didn't seem very clean. Didn't have any cleansing wipes - most airlines give you this when you board. Flat screen scrolling didn't work. Toiletry case a joke - why bother at all?

Enjoyable flight, helpful crew everything was organized to accommodate passengers.

The airline was efficient and accommodating to work with though there was a delay. Appreciate the service and smooth experience!

I was transferred to an American Airlines flight. The boarding was late and unorganized. The seating was extremely tight and uncomfortable. Will not use AA again.

The check-in of my luggage was terrible. When purchased my tickets, one luggage and one carry-on was part of the fight. My flight was switched from British to American Airline. During check-in of luggage at the airport, I was denied and had to pay extra $75. How do I get reimbursed for this extra luggage payment?

This was the second time on BA, food terrible, bathrooms gross,( granted, that was mostly due to the disgusting children urinating all over it)boarding was late and disorganized. No gate issued until last minute st Heathrow, bad system, caused undue stress. Seats were painful, that's what you get for traveling like a poor in economy, right BA? Should have been able to afford business or first class if you want to actually be able to walk upright without back pain after a trip.

The delay was not communicated via text and the person who helped with check in also didn’t inform me about the delay. I ended up missing my connection and it was a waste of 5 hours. The crew didn’t mention there would be someone at the gate informing of if I would be rebooked and there was no signage. Overall a very poor experience. The British Airways app was also very buggy, and didn’t work. I will avoid flying with British Airways when possible.

Cancelled flight minutes before boarding. Rescheduled flight was two days later

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