$209 Find Cheap Flights from Santa Ana to Italy

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Italy departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Santa Ana to Italy

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Florence
Florence2 stops$617
Naples
Naples2 stops$571
Palermo
Palermo2 stops$677
Catania
Catania2 stops$550
Bologna
Bologna2 stops$610
Pisa
Pisa2 stops$823
Turin
Turin2 stops$634
Genoa
Genoa2 stops$615
Verona
Verona2 stops$685
Florence
Florence2 stops$617
Naples
Naples2 stops$571
Palermo
Palermo2 stops$677
Catania
Catania2 stops$550
Bologna
Bologna2 stops$610
Pisa
Pisa2 stops$823
Turin
Turin2 stops$634
Genoa
Genoa2 stops$615
Verona
Verona2 stops$685

Book Cheap Santa Ana to Italy Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Italy that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Italy

Mon, Mar 2 - Wed, Mar 11
Multiple Airlines Logo
12:25 pm - 9:55 am
SNA
-
MXP
36h 30m
2 stops
Multiple Airlines Logo
12:05 pm - 10:09 am
MXP
-
SNA
30h 04m
2 stops
$494Multiple Airlines
Mon, Mar 2 - Tue, Mar 17
United Airlines Logo
6:35 pm - 9:55 am
SNA
-
MXP
30h 20m
3 stops
United Airlines Logo
9:45 am - 7:54 pm
MXP
-
SNA
18h 09m
1 stop
$495United Airlines
Mon, Mar 23 - Wed, Apr 22
British Airways Logo
3:24 pm - 4:20 pm
SNA
-
LIN
16h 56m
2 stops
British Airways Logo
7:25 am - 9:13 pm
LIN
-
SNA
22h 48m
2 stops
$496British Airways
Mon, Mar 2 - Wed, Mar 11
United Airlines Logo
6:35 pm - 7:30 am
SNA
-
MXP
27h 55m
3 stops
United Airlines Logo
9:45 am - 10:15 pm
MXP
-
SNA
20h 30m
2 stops
$496United Airlines
Mon, Mar 2 - Mon, Mar 16
British Airways Logo
12:47 pm - 7:50 pm
SNA
-
MXP
22h 03m
2 stops
British Airways Logo
8:50 pm - 9:39 pm
MXP
-
SNA
32h 49m
2 stops
$507British Airways
Tue, Apr 21 - Wed, May 6
Delta Logo
1:12 pm - 2:45 pm
SNA
-
MXP
16h 33m
2 stops
Delta Logo
11:40 am - 7:47 pm
MXP
-
SNA
17h 07m
1 stop
$511Delta
Mon, Apr 20 - Wed, May 6
Air Canada Logo
12:25 pm - 10:20 am
SNA
-
MXP
36h 55m
2 stops
Air Canada Logo
12:20 pm - 12:20 pm
MXP
-
SNA
57h 00m
2 stops
$515Air Canada
Tue, Apr 21 - Wed, May 6
Delta Logo
1:12 pm - 1:55 pm
SNA
-
LIN
15h 43m
2 stops
Delta Logo
6:40 am - 4:12 pm
LIN
-
SNA
18h 32m
2 stops
$519Delta
Tue, Apr 7 - Wed, Apr 15
Air Canada Logo
12:25 pm - 10:20 am
SNA
-
MXP
36h 55m
3 stops
Air Canada Logo
12:20 pm - 11:12 am
MXP
-
SNA
55h 52m
2 stops
$520Air Canada
Tue, Mar 31 - Fri, Apr 10
Lufthansa Logo
7:15 am - 12:50 pm
SNA
-
BLQ
20h 35m
2 stops
Lufthansa Logo
1:30 pm - 9:58 pm
BLQ
-
SNA
17h 28m
2 stops
$772Lufthansa
Booking Insights

KAYAK's insights & trends for Santa Ana to Italy flights

Get data-powered insights and trends into flights from Santa Ana to Italy to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Santa Ana to Italy?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Ana to Italy, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santa Ana to Italy is November, when tickets cost $509 (return) on average. On the other hand, the most expensive months are December and July, when the average cost of round-trip tickets is $1,440 and $928 respectively.

Good to know

Low seasonJanuary
Cheapest flight$209
Best time to beat the crowds with an average 36% drop in price.
Most popular time to fly with an average 4% increase in price.
Flight from John Wayne (Santa Ana) to Florence

FAQs - booking Italy flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Italy?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Italy.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Italy?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Italy is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Italy?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Italy with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Italy?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Italy up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Santa Ana to Italy

 
Need help choosing which airline to fly with from Santa Ana to Italy? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8207 reviews
7.9Comfort
8.5Crew
7.2Food
8.1Boarding
7.8Entertainment
Airline reviews

Everything I mentioned earlier - the airbus was more comfortable indeed and the experience was further enhanced.

10.0 ExcellentSoosnata, Feb 2026
LAX - HNL
Read more Delta reviews

Everything I mentioned earlier - the airbus was more comfortable indeed and the experience was further enhanced.

The plane was an older model, so it wasn’t as comfortable as others. The flight attendants were not helpful during onboarding. It was a full flight so there was chaos finding space for baggage.

Awesome! On time flight, early arrival, and a complimentary upgrade!

It was nt delta. It was aeromexo. Service was awful. They served a very small drink and NO snack for a 3hr and 35min flight. Then for the first 30 min of the flight is was talk and talk over head interruption the movie/ show i picked to watch.

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

Delta’s staff is unmatched. From the gate agents, to the pilots, to the flight attendants… all top of the industry.

The flight was delayed for about 2 hrs. Other than it, it was good.

I am extremely disappointed that delta internal pilot manuals now refer to the Gulf of Mexico as the “gulf of America”. You can bow down to the Orange turd on your own. I will never fly delta again

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

Entertainment kept turning itself off. Gave up on watching a movie.

Very disappointing given gate agent behavior. Filed a formal complaint with United.

Crew was great (professional, attentive, prompt). Snacks for 4 hrs flight is deplorable.

Flight delayed. WiFi connectivity very poor if not existant. Last minute arrival forced me to run to catch my connection.

Terrible. No customer service, no food, no drinks on a 6 hour premier economy booking.

Check-in and in-flight staff were better than average. The seat was a fair size but too hard and not enough padding. The cushion/pillow provided is poor (thin and seems to be disposable ,it provides no effective cushioning or support). Food was OK-ish but no choice of inflight snacks and no easy place to get drinks other than water (I could ask for juice by intruding into the staff area at the back of the plane) Entertainment was very good actually. Overall better than I expected from a US-based airline (sorry!) but compared to ANA or Singapore it was so-so. (I live in Japan so they are my comparative airlines)

Terrible. Our first time back on United for 10 years, the seats in Polaris class are small and uncomfortable. They have squished too many people in to get more $$$. The staff are not friendly and not wanting to accommodate. I asked for two salads rather than a main meal and was advised no we wont do that. Then asked what I would like for breakfast and given something else anyway. I will not be flying United International anytime soon.

The food was terrible this time. Otherwise pleasant, quiet, on-time.

It was a pretty standard flight... until the almost hour and a half spent on the taxi way. I get that the weather has been poor but the delay had nothing to do with the weather and more to do with a plane with several issues tying up the gate. I get that that happens from time to time but this has been EVERY flight I've been on for the past 5 years and I fly 3 to 5 times a year. This isn't just United... it's American, it's Delta. It's an issue with the entire industry. I work for UPS and packages on a cargo plane get better service than people do these days. Anymore I HATE flying.

The flight crew where really good. Better then the crew from BNE to SFO

Service and food were excellent. Incredibly friendly and competent staff. Flight was delayed over and hour and I had to run between terminals to get my connecting flight.

Late flight Delays Poor service Poor staff Worst airline ever

Lufthansa still has a good level of quality compared to US airlines, especially with respect to (1) food quality - actually tasty, (2) good French red wine - free, (3) good movie selection. Also my ticket price includes 1 free check-in luggage, while some other budget airlines sneak in an extra $150 for a checkin.

The food could be better, more snacks. And have some plugs to chargue the phone.

Everything was really great just The aircraft was too old and sounded it will break during takeoff

Extremely pleased with the crew. Best flight attendants ever! Very friendly, genuinely caring and attentive.

Best flight attendants ever! Very customer and service oriented, courteous, professional and helpful.

Cheapest airlines I have ever been on. I got downgraded and never got on united. I got rerouted through Vancouver onto jetwesf

Very small and uncomfortable seats, Hard to hear entertainment system sound. Horrible food. Staff doesn't care much about the passengers. 2nd time they didn't give me my vegetarian meal. They asked me regular food with meat. The airline and staff was from United airlines.

Checkin took along timen only.few angents available at.checkin desk. Customer support over phone no existence

First, ITA lost my bag and the baggage team showed no regard in trying to find it. Second, I had paid for priority boarding as part of a first class ticket and instead they disregarded boarding groups and we all boarded at the same time. Third, wasn't allowed to select my seat in advance even with a first class ticket. When I was assigned bulkhead, I was told I would need to pay to change my seat. Overall, very disappointing experience.

The seats needs to be spruced up , for a long flight very uncomfortable , cushions are worn out but everything else is very good , crew is great.

I guess that was fine with ITA but the Rome airport is so difficult to navigate with so many checkpoints getting new tickets from what was originally given to me

I did not leave to Italy yet. We had technical problems on flight from SF to Maimi and had to land in Denver and wait for another plane to take us to Miami, so I missed my plane to Italy. I am still waiting for the Agency to fix my flight till today the haven’t done anything and I am paying for my Hotel stay. Everyday they are promising to fix my flight, they are not doing so and they are not even looking for another solution

My seat was broken and ducted taped and my monitor did not work the entire time over 8 hrs sitting. And I had no books or anything with me

my flight from Rome to Boston was on a very old plane. My video and audio did not work.

Good with timing of flights. The crew was exceptionally unfriendly. I heard more than one person say this. And even with the aisle, it seemed more uncomfortable than usual. The movie selection was old and poor, but the dinner was great - the lasagna and tiramisu.

The check in process is chaotic. It says partially checked-in. Never heard of such a thing. Then lost our reserved seats when we finally checked in at the airport. The seats don’t recline. Then we had to get mew boarding passes at the connection. Last, my companion lost her baggage and up to now there’s no update. We’re already half-way through our vacation and still no news what happened to the luggage.

Wonderful! Everyone very helpful and kind. Returning flight was cancelled but rebooking was easy.

Pretty normal flight was delayed due to traffic could have missed connecting flight to Venice but crew kept us well informed so we made it

Everything you need to know for your flight from Santa Ana to Italy

Information on your arrival and departure airports