VVI - PTY

$338 Find Cheap Flights from Santa Cruz de la Sierra to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Cruz de la Sierra to Panama City departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Cruz de la Sierra to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Cruz de la Sierra to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$623
Typical prices: $443-$680
Copa Airlines
Thu 3/19Fri 3/27
VVI - PTY • Non-stop
Cheapest one-way
$338
Typical prices: $280-$789
Avianca
Mon 12/22
VVI - PTY • 1 stop
Our travelers' advice
AI-generated summary based on content written by travel experts
Copa's Showpass offers digital entertainment onboard.
United's Wi-Fi allows free messaging for all flyers.
Expert advice
Expert advice
Expert advice
Expert advice
When to book
6 weeks
in advance
Our data shows that travelers who book at least 6 weeks in advance save around 13% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
May
Cheapest • 28% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Santa Cruz de la Sierra to Panama City (VVI-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Cruz de la Sierra to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Cruz de la Sierra to Panama City

Thu, Mar 19 - Fri, Mar 27
Copa Airlines Logo
1:14 am - 5:04 amVVI-PTY
4h 50mnonstop
Copa Airlines Logo
9:43 pm - 3:38 amPTY-VVI
4h 55mnonstop
$623Copa Airlines
Find Deal
Tue, Mar 10 - Mon, Mar 16
Avianca Logo
3:40 am - 2:00 pmVVI-PTY
11h 20m1 stop
Avianca Logo
2:55 pm - 2:35 amPTY-VVI
10h 40m1 stop
$632Avianca
Find Deal
Tue, Dec 23 - Wed, Dec 31
Copa Airlines Logo
1:09 am - 5:04 amVVI-PTY
4h 55mnonstop
Copa Airlines Logo
4:40 pm - 10:46 pmPTY-VVI
5h 06mnonstop
$651Copa Airlines
Find Deal
Mon, Dec 22 - Thu, Jan 29
Avianca Logo
3:40 am - 2:00 pmVVI-PTY
11h 20m1 stop
Avianca Logo
5:50 pm - 2:35 amPTY-VVI
7h 45m1 stop
$665Avianca
Find Deal
Wed, Mar 4 - Mon, Mar 9
Copa Airlines Logo
1:14 am - 5:04 amVVI-PTY
4h 50mnonstop
Copa Airlines Logo
9:43 pm - 3:38 amPTY-VVI
4h 55mnonstop
$671Copa Airlines
Find Deal
Tue, Dec 9 - Wed, Dec 17
Avianca Logo
3:40 am - 2:00 pmVVI-PTY
11h 20m1 stop
Avianca Logo
9:45 am - 2:35 amPTY-VVI
15h 50m1 stop
$691Avianca
Find Deal
Tue, Jan 27 - Tue, Feb 3
Copa Airlines Logo
1:15 am - 5:04 amVVI-PTY
4h 49mnonstop
Copa Airlines Logo
4:40 pm - 10:50 pmPTY-VVI
5h 10mnonstop
$697Copa Airlines
Find Deal
Thu, Mar 5 - Mon, Mar 9
Copa Airlines Logo
11:42 am - 3:35 pmVVI-PTY
4h 53mnonstop
Copa Airlines Logo
9:43 pm - 3:38 amPTY-VVI
4h 55mnonstop
$699Copa Airlines
Find Deal
Fri, Dec 26 - Mon, Jan 5
Avianca Logo
3:40 am - 4:55 pmVVI-PTY
14h 15m1 stop
Avianca Logo
9:45 am - 2:35 amPTY-VVI
15h 50m1 stop
$724Avianca
Find Deal
Mon, Dec 22 - Wed, Jan 28
Multiple Airlines Logo
3:40 am - 2:00 pmVVI-PTY
11h 20m1 stop
Multiple Airlines Logo
2:55 am - 10:35 amPTY-VVI
30h 40m2 stops
$733Multiple Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Santa Cruz de la Sierra to Panama City flights

Get data-powered insights and trends into flights from Santa Cruz de la Sierra to Panama City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santa Cruz de la Sierra to Panama City?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santa Cruz de la Sierra to Panama City departing in March.

What’s the cheapest day of the week to fly from Santa Cruz de la Sierra to Panama City?

The average price of all round-trip flights from Santa Cruz de la Sierra to Panama City clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Panama City on a Saturday and more expensive on a Friday. On your return trip to Santa Cruz de la Sierra, you should consider flying back on a Sunday, and avoid Thursdays for better deals.

What is the cheapest month to fly from Santa Cruz de la Sierra to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Cruz de la Sierra to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santa Cruz de la Sierra to Panama City is May, where tickets cost $413 (return) on average. On the other hand, the most expensive months are January and July, where the average cost of round-trip tickets is $711 and $663 respectively.

Can I save money by flying with a layover from Santa Cruz de la Sierra to Panama City?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $657 on average.

How far in advance should I book a flight from Santa Cruz de la Sierra to Panama City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santa Cruz de la Sierra to Panama City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santa Cruz de la Sierra to Panama City, you should book around 6 weeks before departure, which saves you about 13% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Expert advice

Expert advice for your flight from Santa Cruz de la Sierra to Panama City

 
Snippets provided in this section are AI-generated based on a summarization of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
United Airlines

United's Polaris cabin offers lie-flat seats with aisle access, ideal for comfort on longer flights.


United's Wi-Fi offers free messaging; T-Mobile customers enjoy free streaming, enhancing connectivity.

Copa Airlines

Copa's B737 MAX 9 offers lie-flat beds in business class, enhancing comfort on medium-haul flights.


Copa's Showpass system allows digital entertainment on personal devices, enhancing in-flight experience.

Our travel experts
Stefanie Waldek

Stefanie Waldek

Expert on United Airlines

Stefanie Waldek

Stefanie Waldek

Stefanie Waldek is a freelance space, travel, and design writer based in Saratoga Springs, NY. Her words have appeared in Space.com, Travel + Leisure, Condé Nast Traveler, Architectural Digest, and House Beautiful, among other publications. An expert in aviation and expedition cruising, Stefanie is frequently up in the air or on the sea, likely en route to Antarctica or the Arctic.

Read more
Ramsey Qubein

Ramsey Qubein

Expert on Copa Airlines

Ramsey Qubein

Ramsey Qubein

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Read more

Good to know

Low seasonSeptember
Cheapest flight$338
Best time to beat the crowds with an average 15% drop in price.
Most popular time to fly with an average 13% increase in price.
Flight from Santa Cruz de la Sierra to Panama City

When to book flights from Santa Cruz de la Sierra to Panama City

Are your dates flexible? Find out the best times to travel from Santa Cruz de la Sierra to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santa Cruz de la Sierra to Panama City

  • What is the cheapest flight from Santa Cruz de la Sierra to Panama City?

    In the last 3 days, the lowest price for a flight from Santa Cruz de la Sierra to Panama City was $338 for a one-way ticket and $623 for a round-trip.

  • Do I need a passport to fly between Santa Cruz de la Sierra and Panama City?

    A passport is required to fly from Santa Cruz de la Sierra to Panama City.

  • Which aircraft models fly most regularly from Santa Cruz de la Sierra to Panama City?

    The Airbus A330-200 is the aircraft model that flies most regularly on the Santa Cruz de la Sierra to Panama City flight route.

  • Which airline alliances offer flights from Santa Cruz de la Sierra to Panama City?

    Star Alliance is the only airline alliance operating flights between Santa Cruz de la Sierra and Panama City.

  • On which days can I fly direct from Santa Cruz de la Sierra to Panama City?

    There are nonstop flights from Santa Cruz de la Sierra to Panama City on a daily basis.

  • Which is the best airline for flights from Santa Cruz de la Sierra to Panama City, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Santa Cruz de la Sierra to Panama City are Copa Airlines and Avianca. With an average price for the route of $662 and an overall rating of 7.6, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $513 and an overall rating of 6.6.

  • How does KAYAK find such low prices on flights from Santa Cruz de la Sierra to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santa Cruz de la Sierra to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santa Cruz de la Sierra to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Santa Cruz de la Sierra is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santa Cruz de la Sierra to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Santa Cruz de la Sierra with another airline. Booking your flights between Santa Cruz de la Sierra and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santa Cruz de la Sierra to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Santa Cruz de la Sierra up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Santa Cruz de la Sierra to Panama City

  • Looking for a cheap flight? 25% of our users found flights on this route for $387 or less one-way and $643 or less round-trip.

Prefer to fly direct from Santa Cruz de la Sierra to Panama City?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Santa Cruz de la Sierra Viru Viru Intl to Panama City Tocumen Intl.
Find which airlines fly direct from Santa Cruz de la Sierra Viru Viru Intl Airport to Panama City Tocumen Intl Airport, which days they fly and book direct flights.

Direct departures

Santa Cruz de la Sierra Viru Viru Intl to Panama City Tocumen Intl

Monday

BoA, Copa Airlines

BoA, Copa Airlines

Tuesday

BoA, Copa Airlines

BoA, Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

BoA, Copa Airlines

BoA, Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

BoA, Copa Airlines

BoA, Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

Panama City Tocumen Intl to Santa Cruz de la Sierra Viru Viru Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

BoA, Copa Airlines

BoA, Copa Airlines

Wednesday

BoA, Copa Airlines

BoA, Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

BoA, Copa Airlines

BoA, Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

BoA, Copa Airlines

BoA, Copa Airlines

See more direct flights

Reviews of the top airlines flying from Santa Cruz de la Sierra to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Santa Cruz de la Sierra to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Cruz de la Sierra to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1568 reviews
7.8Boarding
6.8Entertainment
8.1Crew
7.4Comfort
6.8Food
Airline reviews

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

8.0 ExcellentTisagh, Nov 2025SDQ - PTY
Read more Copa Airlines reviews

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

I selected first class expecting excetional service. It was mediocre at best. The food service was cold, meal choices was poor and on one leg they did provide dessert. I did enjoy the lay day seat but the movies were old and nothing current. Boarding the plane is always hot. So boarding is quite warm until your in the air. I took a small personal air fan. Update the meals and movies.

I had to go to the boarding counter for them to enter my return flight as it’s not with Avianca. There was a long queue as there were lots of people being called to the counter.

6 hour flight and have to pay for everything 100 dollars to add a carry-on bag is insane

Did not fly with Pakistan International Airlines. Have never flown with Pakistan International Airlines.

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

The seats were uncomfortable and barely reclined at all. Very little leg room despite being business class. The crew was friendly and the food was good. Had to use my own phone for in-flight entertainment.

Avianca is not what it used to be. So disappointing

The incoming plane was late and no information was shared. They even announced we would board in 10 muntes 40 minutes prior to the plane arriving, and the website said until takeoff that we had taken off an hour earlier

Seats are very tight even in Plus, no complimentary snacks or beverage

Flight to Bogotá delayed by 3 h Missed connection from Bogotá to Guayaquil. Avianca unable to bring us to Baltra on time Overall delay 36h. We missed boat departure from galagos. Overall 10 day trip needed to be cancelled. Avianca was completely un-professional.

i think the flight was late because they were so strict about measuring everyone's personal items to try and charge them $119. It was really petty and made us late.

Everything you need to know for your flight from Santa Cruz de la Sierra to Panama City

Information on your arrival and departure airports