$429 Find Cheap Flights from Santa Cruz de la Sierra to Panama City - Compare and Save

Among airlines operating Santa Cruz de la Sierra to Panama City flights:

• Copa Airlines: offers extra legroom; offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Only Copa Airlines operates flights between Santa Cruz de la Sierra and Panama City.

Flights from Santa Cruz de la Sierra to Panama City usually depart from Santa Cruz de la Sierra Viru Viru Intl (VVI) and arrive at Panama City Tocumen Intl (PTY).

Here are some options for this route, based on selected ticket types and cabin classes:

• Copa Airlines: a cabin bag and a checked bag in Economy Class

Bag allowance can vary by ticket type, cabin class, route and airline, so travelers should check the fare details before booking.

Only Economy Class is available on flights from Santa Cruz de la Sierra to Panama City.

On this route, layover flights are cheaper than nonstop options on average. Layover fares average $695 round-trip via Bogotá El Dorado (BOG), compared to $737 for nonstop.

There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $85–$100 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

The Airbus A330-200 family is used most often on this route, operated mainly by BoA and Iberia. Other aircraft seen on the route include Boeing 737-800 variants.

Most connecting flights from Santa Cruz de la Sierra to Panama City pass through Bogotá El Dorado (BOG), which handles 100% of one-stop traffic on this route. Other layover airports each see under 5%.

On the Santa Cruz de la Sierra to Panama City route, being flexible with your departure day can save you up to 9%. Sunday is the cheapest day at $696 round-trip on average, while Thursday is the most expensive at $759: a $63 difference. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

Morning is the busiest departure period on Santa Cruz de la Sierra to Panama City flights, with 50% of flights leaving in that window. Night departures account for 50%, afternoon flights for 0%, and evening flights for 0%.

Some of the most popular sights in Panama City are Avenida Balboa, Panama City Centre and Multiplaza Pacific. These are among the most viewed places in Panama City on KAYAK.

These are the earliest and latest flight times available from Santa Cruz de la Sierra to Panama City:

• Earliest: departs at 1:08 am and lands at 6:03 am
• Latest: departs at 11:55 am and lands at 4:50 pm.

The flight takes about 4h 55m.

Last-minute fares on this route - booked within 2 weeks of departure - run 29% above the route average of $735. Book 16 weeks before departure for the lowest fares.

A nonstop flight from Santa Cruz de la Sierra to Panama City takes 4h 55m, covering 2,152 miles.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $742 to $1,925. That means the highest observed fare was about 3x higher than the lowest one.

One-way fares from Santa Cruz de la Sierra to Panama City are currently higher than usual. Average one-way flight prices are about $522, which is 26% above the typical average for this route.

Panama City is 1 hour behind Santa Cruz de la Sierra (Eastern Time vs Bolivia Time). Plan for the time shift when scheduling connections or first-day activities.

Panama City Tocumen Intl Airport (PTY) hosts 5 major car rental companies, with daily rates starting from around $1 for economy cars. Top options include:
· Avis
· Europcar
· Ace
· Budget
· Hertz

Round-trip flights from Santa Cruz de la Sierra to Panama City range from $647 to $833, with an average of $735 over the past 12 months. Anything below $647 counts as a good deal.