$232 Find Cheap Flights from Santiago to Guayaquil - Compare and Save

If you are looking for a flight deal from Santiago to Guayaquil, look for departures on Saturdays and avoid leaving on a Sunday, as it's usually the priciest day. When flying back from Guayaquil, Friday is the cheapest day to fly and Sunday is the most expensive.

The cheapest month for flights from Santiago to Guayaquil is October, where tickets cost $421 (return) on average. On the other hand, the most expensive months are January and December, where the average cost of round-trip tickets is $548 and $503 respectively.

No, with an average price for the route of $381, prices are generally cheapest when you fly direct.

To get a below average price on the flight from Santiago to Guayaquil, you should book around 3 weeks before departure, which saves you about 11% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

In the past 5 days, the cheapest round-trip tickets from Santiago to Guayaquil were found on Avianca ($429) and LATAM Airlines ($457).

There is just one airline that flies from Santiago to Guayaquil direct and that is LATAM Airlines. The best round-trip deal found from LATAM Airlines for the route is $320.

Weekly flights between Santiago and Guayaquil historically see delays in approximately 8% of cases, with the average delay over the past year being 151 minutes.

Typically, flights leaving in the morning tend to face fewer delays, whereas flights at night have historically encountered delays more often.

Statistically, Friday is the day of the week with the fewest delays on this flight route, while Monday has typically experienced more delays than other days.

Based on our data, LATAM Airlines have experienced the fewest delays on this route in the past 12 months, with only about 8% of their flights encountering any delays.

Lima (LIM) is the top choice – 91% of KAYAK users who clicked on 1-stop flights from Santiago to Guayaquil picked an itinerary connecting there.

Flights via Bogotá (BOG) offer the most affordable fares, with an average round-trip price of $398.

Consider flying via Bogotá (BOG) for the shortest journey. The average one-way travel time for flights connecting there is 9h 10m.

If you prefer a quick connection, Bogotá (BOG) often has the shortest layovers from Santiago to Guayaquil, with an average of 1h 10m.

There are 2 cabin class options for the route. These are Economy and Prem Economy. Perform a search on KAYAK to find the latest prices and availability for all cabin fares, which differ across airlines.

There is a maximum of 1 nonstop flight a day that takes off from Santiago and lands in Guayaquil, with an average flight time of 5h 18m. The most common departure time is 12:00 am and most flights take off at night. Each week, there are 7 flights.