$210 Find Cheap Flights from Santiago to Guayaquil - Compare and Save

These are the earliest and latest flight times available from Santiago to Guayaquil:

• Earliest: departs at 1:45 am and lands at 7:03 am
• Latest: departs at 1:45 am and lands at 7:03 am.

The flight takes about 5h 18m.

Two cabin classes are available on flights from Santiago to Guayaquil:

• Economy Class
• Business Class

A nonstop flight from Santiago to Guayaquil takes 5h 18m, covering 2,235 miles.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Round-trip flights from Santiago to Guayaquil range from $445 to $579, with an average of $502 over the past 12 months. Anything below $445 counts as a good deal.

Last-minute fares on this route (booked within two weeks of departure) run 14% above the $502 route average. Book 22 weeks before departure for the lowest fares.

On this route, layover flights are cheaper than nonstop options on average. Layover fares average $471 round-trip via Bogotá El Dorado (BOG), compared to $521 for nonstop.

LATAM Airlines is the only airline operating Santiago to Guayaquil flights. 89% of its flights are on time.

There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $37–$100 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

The Airbus A319 family is used most often on this route, operated mainly by LATAM Airlines. Other aircraft seen on the route include Boeing 787-8 Dreamliner variants.

Night is the busiest departure period on Santiago to Guayaquil flights, with 100% of flights leaving in that window. Morning departures account for 0%, afternoon flights for 0%, and evening flights for 0%.

One-way fares from Santiago to Guayaquil are currently lower than usual. Average one-way flight prices are about $230, which is 7% below the typical average for this route.

Guayaquil Jose Joaquin de Olmedo Airport (GYE) hosts 5 major car rental companies, with daily rates averaging $37 for economy cars. Top options include:

• Europcar
• Fox
• Sixt
• Alamo
• keddy by Europcar

Flights from Santiago to Guayaquil usually depart from Santiago Arturo Merino Benitez (SCL) and arrive at Guayaquil Jose Joaquin de Olmedo (GYE).

Night flights have the fewest delays on this route.

A flight is considered delayed when it departs 15 minutes or more after its scheduled time. This is the standard used by the US Department of Transportation and most airline industry reporting. On the Santiago to Guayaquil route, 11% of flights were delayed in the past 3 months, with delays averaging 2h 24m.

One-stop flights from Santiago to Guayaquil most commonly connect through:

• Lima J Chavez Intl (LIM) - 53% of one-stop connections
• Bogotá El Dorado (BOG) - 37% of one-stop connections
• Panama City Tocumen Intl (PTY) - 9% of one-stop connections
• Quito Mariscal Sucr (UIO) - 0% of one-stop connections

Yes. Flexible dates can save you up to 4% on flights from Santiago to Guayaquil. Thursday is the cheapest departure day at $493 round-trip on average, while Sunday is the most expensive at $513, a difference of $20.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Only LATAM Airlines operates flights between Santiago and Guayaquil.

Flying via Lima J Chavez Intl (LIM) gives the shortest average 1-stop total travel time at 9h 01m, compared with 10h 59m via Bogotá El Dorado (BOG) and 12h 18m via Quito Mariscal Sucr (UIO).

Guayaquil is 2 hours behind Santiago (Ecuador Time vs Chile Time). Plan for the time shift when scheduling connections or first-day activities.

Among airlines operating Santiago to Guayaquil flights:

• LATAM Airlines: offers extra legroom; offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Here are some options for this route, based on selected ticket types and cabin classes:

• LATAM Airlines: a cabin bag and a checked bag in Economy Class

Bag allowance can vary by ticket type, cabin class, route and airline, so always check the fare details before booking.