SCL - GYE

$188 Find Cheap Flights from Santiago to Guayaquil

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to Guayaquil departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Guayaquil

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Guayaquil, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Guayaquil, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Santiago to Guayaquil (SCL-GYE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to Guayaquil that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to Guayaquil

Thu, Aug 28 - Tue, Sep 2
Avianca Logo
11:55 pm - 9:55 amSCL-GYE
11h 00m1 stop
Avianca Logo
3:35 am - 1:25 pmGYE-SCL
8h 50m1 stop
$398Avianca
Find Deal
Wed, Nov 5 - Thu, Nov 6
Avianca Logo
1:35 am - 9:15 amSCL-GYE
9h 40m1 stop
Avianca Logo
3:30 am - 3:20 pmGYE-SCL
9h 50m1 stop
$399Avianca
Find Deal
Thu, Aug 28 - Fri, Sep 12
Copa Airlines Logo
12:24 am - 11:15 amSCL-GYE
11h 51m1 stop
Copa Airlines Logo
12:17 pm - 12:04 amGYE-SCL
9h 47m1 stop
$401Copa Airlines
Find Deal
Fri, Sep 19 - Fri, Sep 26
LATAM Airlines Logo
11:50 pm - 3:13 amSCL-GYE
5h 23mnonstop
LATAM Airlines Logo
12:55 pm - 10:50 pmGYE-SCL
7h 55m1 stop
$412LATAM Airlines
Find Deal
Wed, Nov 5 - Tue, Nov 11
LATAM Airlines Logo
12:45 am - 4:03 amSCL-GYE
5h 18mnonstop
LATAM Airlines Logo
1:00 pm - 11:25 pmGYE-SCL
8h 25m1 stop
$413LATAM Airlines
Find Deal
Thu, Nov 6 - Tue, Nov 11
LATAM Airlines Logo
8:50 am - 2:10 pmSCL-GYE
7h 20m1 stop
LATAM Airlines Logo
4:48 pm - 11:35 pmGYE-SCL
4h 47mnonstop
$414LATAM Airlines
Find Deal
Wed, Nov 5 - Tue, Nov 11
LATAM Airlines Logo
12:45 am - 4:03 amSCL-GYE
5h 18mnonstop
LATAM Airlines Logo
4:48 pm - 11:35 pmGYE-SCL
4h 47mnonstop
$415LATAM Airlines
Find Deal
Fri, Nov 28 - Sat, Jan 10
Copa Airlines Logo
5:12 am - 8:43 pmSCL-GYE
17h 31m1 stop
Copa Airlines Logo
8:34 am - 8:20 pmGYE-SCL
9h 46m1 stop
$421Copa Airlines
Find Deal
Thu, Sep 25 - Fri, Oct 3
 Logo
12:55 am - 8:35 amSCL-GYE
9h 40m1 stop
 Logo
2:45 pm - 9:38 pmGYE-SCL
4h 53mnonstop
Fri, Sep 26 - Sat, Oct 4
 Logo
12:55 am - 8:35 amSCL-GYE
9h 40m1 stop
 Logo
2:45 pm - 9:38 pmGYE-SCL
4h 53mnonstop
Booking Insights

KAYAK's insights & trends for Santiago to Guayaquil flights

Get data-powered insights and trends into flights from Santiago to Guayaquil to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santiago to Guayaquil?

What’s the cheapest day of the week to fly from Santiago to Guayaquil?

The average price of all round-trip flights from Santiago to Guayaquil clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Santiago to Guayaquil, look for departures on Mondays and avoid leaving on a Sunday, as it's usually the priciest day. When flying back from Guayaquil, Thursday is the cheapest day to fly and Saturday is the most expensive.

What is the cheapest month to fly from Santiago to Guayaquil?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santiago to Guayaquil, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santiago to Guayaquil is November, where tickets cost $348 (return) on average. On the other hand, the most expensive months are January and February, where the average cost of round-trip tickets is $477 and $463 respectively.

Can I save money by flying with a layover from Santiago to Guayaquil?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $197 on average.

How far in advance should I book a flight from Santiago to Guayaquil?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santiago to Guayaquil, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santiago to Guayaquil, you should book around 5 weeks before departure, which saves you about 28% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Good to know

Low seasonApril
Cheapest flight$188
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly with an average 7% increase in price.
Flight from Santiago to Guayaquil

When to book flights from Santiago to Guayaquil

Are your dates flexible? Find out the best times to travel from Santiago to Guayaquil based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santiago to Guayaquil

  • What is the cheapest flight from Santiago to Guayaquil?

    In the last 3 days, the lowest price for a flight from Santiago to Guayaquil was $188 for a one-way ticket and $398 for a round-trip.

  • Do I need a passport to fly between Santiago and Guayaquil?

    Yes, you’ll need a passport to travel to Guayaquil from Santiago.

  • Which airports will I be using when flying from Santiago to Guayaquil?

    On your way to Guayaquil, you’ll fly out from Santiago Arturo Merino Benitez. You’ll be landing at Guayaquil Jose Joaquin de Olmedo.

  • Which airlines offer Wi-Fi service onboard planes from Santiago to Guayaquil?

    Only American Airlines offers inflight Wi-Fi service on the Santiago to Guayaquil flight route.

  • Which aircraft models fly most regularly from Santiago to Guayaquil?

    The Airbus A319 is the aircraft model that flies most regularly on the Santiago to Guayaquil flight route.

  • On which days can I fly direct from Santiago to Guayaquil?

    There are nonstop flights from Santiago to Guayaquil on a daily basis.

  • How does KAYAK find such low prices on flights from Santiago to Guayaquil?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to Guayaquil.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to Guayaquil?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Guayaquil from Santiago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to Guayaquil?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Guayaquil with an airline and back to Santiago with another airline. Booking your flights between Santiago and GYE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to Guayaquil?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Guayaquil from Santiago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Santiago to Guayaquil

  • Looking for a cheap flight? 25% of our users found flights on this route for $197 or less round-trip.

Prefer to fly direct from Santiago to Guayaquil?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo.
Find which airlines fly direct from Santiago Arturo Merino Benitez Airport to Guayaquil Jose Joaquin de Olmedo Airport, which days they fly and book direct flights.

Direct departures

Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo

Monday

LATAM Airlines

LATAM Airlines

Tuesday

LATAM Airlines

LATAM Airlines

Wednesday

LATAM Airlines

LATAM Airlines

Thursday

LATAM Airlines

LATAM Airlines

Friday

LATAM Airlines

LATAM Airlines

Saturday

LATAM Airlines

LATAM Airlines

Sunday

LATAM Airlines

LATAM Airlines

See more direct flights

Direct returns

Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez

Monday

LATAM Airlines

LATAM Airlines

Tuesday

LATAM Airlines

LATAM Airlines

Wednesday

LATAM Airlines

LATAM Airlines

Thursday

LATAM Airlines

LATAM Airlines

Friday

LATAM Airlines

LATAM Airlines

Saturday

LATAM Airlines

LATAM Airlines

Sunday

LATAM Airlines

LATAM Airlines

See more direct flights

Reviews of the top airline flying from Santiago to Guayaquil

 
See real verified KAYAK customer reviews for airlines flying from Santiago to Guayaquil. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to Guayaquil? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1840 reviews
7.6Boarding
8.0Crew
6.7Food
7.4Comfort
7.0Entertainment
Airline reviews

The flight was late. Please do not delay next time.

6.0 GoodAnonymous, Aug 2025AUS - ATL
Read more LATAM Airlines reviews

The flight was late. Please do not delay next time.

Boarding was confusing with a delayed flight because there was no English translation

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

My entertainment did not work. I was very tired from the botched connection, and the poor sleep

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

entertainment was not good; the shoulder strap on Business class seat did not sit well across the body (more like across the neck); the food was not hot and the special meal promoted by insert in the menu was not available to us

It was a very good flight, no entertainment is the reason for not checking that box.

I was in the last row and they sent me to check in my luggage last minute after boarding. I had to go through the crowd.

Our flight was cancelled and it took them 5 hours to reschedule and the next morning they said we still didn’t have a new ticket.

I travel often with LATAM, it never disappoints me. The service is great, nice crew, latest and some classic movies. I got 3 small meals, cannot complaint. I’ll definitely travel again with them.

Everything you need to know for your flight from Santiago to Guayaquil

Information on your arrival and departure airports

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