GYE - SCL

$206 Find Cheap Flights from Guayaquil to Santiago - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Guayaquil to Santiago departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$397
Typical prices: $342-$530
Avianca
Sun 8/23Sun 8/30
GYE - SCL • 1 stop
Cheapest non-stop
$417
Typical prices: $440-$554
LATAM Airlines
Sun 8/16Thu 8/20
GYE - SCL • Non-stop
Top airlines
Cheapest • from $392 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
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Airline reviews
Airline reviews
+1
Nonstop flights
You can fly direct with LATAM Airlines. Average duration is 4h 51m
Direct flights
Direct flights
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Direct flights
Direct flights
+1
Avoid delays
Most punctual • 92% on-time
Best time • Fewest delays
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $437 (round-trip)
Shortest trip • 8h 32m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 10% price drop
Most popular
Good to know
Good to know
+1
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Good to know
Good to know
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Guayaquil to Santiago (GYE-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Guayaquil to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Guayaquil to Santiago

Sun, Aug 23 - Sun, Aug 30
Avianca Logo
10:05 am - 4:45 am
GYE
-
SCL
17h 40m
1 stop
Avianca Logo
6:40 am - 11:30 pm
SCL
-
GYE
17h 50m
1 stop
$397Avianca
Wed, Aug 5 - Sun, Aug 9
Avianca Logo
10:05 am - 4:45 am
GYE
-
SCL
17h 40m
1 stop
Avianca Logo
6:40 am - 5:35 pm
SCL
-
GYE
11h 55m
1 stop
$408Avianca
Fri, Sep 4 - Thu, Sep 17
Avianca Logo
10:05 am - 11:20 pm
GYE
-
SCL
12h 15m
1 stop
Avianca Logo
7:40 am - 5:35 pm
SCL
-
GYE
11h 55m
1 stop
$409Avianca
Sun, Aug 16 - Thu, Aug 20
LATAM Airlines Logo
5:38 pm - 11:29 pm
GYE
-
SCL
4h 51mnonstop
LATAM Airlines Logo
12:45 am - 5:03 am
SCL
-
GYE
5h 18mnonstop
$417LATAM Airlines
Fri, Oct 23 - Fri, Oct 30
Avianca Logo
3:45 pm - 5:45 am
GYE
-
SCL
12h 00m
1 stop
Avianca Logo
4:25 pm - 1:05 am
SCL
-
GYE
10h 40m
1 stop
$422Avianca
Sun, Aug 9 - Sun, Aug 16
Copa Airlines Logo
6:28 pm - 10:43 pm
GYE
-
SCL
27h 15m
1 stop
Copa Airlines Logo
4:14 am - 8:53 pm
SCL
-
GYE
17h 39m
1 stop
$425Copa Airlines
Sun, Aug 9 - Sat, Aug 15
Multiple Airlines Logo
9:05 am - 4:45 am
GYE
-
SCL
18h 40m
1 stop
Multiple Airlines Logo
7:50 am - 2:45 pm
SCL
-
GYE
7h 55m
1 stop
$426Multiple Airlines
Fri, Oct 23 - Thu, Oct 29
Multiple Airlines Logo
6:01 am - 8:32 pm
GYE
-
SCL
12h 31m
1 stop
Multiple Airlines Logo
12:45 am - 5:03 am
SCL
-
GYE
6h 18mnonstop
$427Multiple Airlines
Mon, Sep 14 - Sun, Sep 20
Avianca Logo
3:45 pm - 5:45 am
GYE
-
SCL
12h 00m
1 stop
Avianca Logo
4:20 pm - 7:30 am
SCL
-
GYE
17h 10m
2 stops
$428Avianca
Mon, Sep 14 - Wed, Sep 30
LATAM Airlines Logo
5:38 pm - 11:29 pm
GYE
-
SCL
3h 51mnonstop
LATAM Airlines Logo
12:35 pm - 1:45 am
SCL
-
GYE
15h 10m
1 stop
$429LATAM Airlines
Booking Insights

KAYAK's insights & trends for Guayaquil to Santiago flights

Get data-powered insights and trends into flights from Guayaquil to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Guayaquil to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Guayaquil to Santiago departing in August.

What’s the cheapest day of the week to fly from Guayaquil to Santiago?

The average price of all round-trip flights from Guayaquil to Santiago clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Santiago on a Friday, as we generally find the cheapest rates on that day for this route. On the other hand, Monday is the most expensive day to fly from Guayaquil to Santiago. For your return ticket, we recommend flying on a Saturday and avoiding Fridays for the best deals.

What is the cheapest month to fly from Guayaquil to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Guayaquil to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Guayaquil to Santiago is November, where tickets cost $423 (return) on average. On the other hand, the most expensive months are February and June, where the average cost of round-trip tickets is $494 and $488 respectively.

Can I save money by flying with a layover from Guayaquil to Santiago?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $465 on average.

How far in advance should I book a flight from Guayaquil to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Guayaquil to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Guayaquil to Santiago, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 5 weeks before departure.

Good to know

Low seasonFebruary
Cheapest flight$206
Best time to beat the crowds but there is an average 5% increase in price.
Flight from Guayaquil to Santiago

When to book flights from Guayaquil to Santiago

Are your dates flexible? Find out the best times to travel from Guayaquil to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Guayaquil to Santiago

  • What is the cheapest flight from Guayaquil to Santiago?

    In the last 5 days, the lowest price for a flight from Guayaquil to Santiago was $206 for a one-way ticket and $392 for a round-trip.

  • Do I need a passport to fly between Guayaquil and Santiago?

    Yes

  • Which airports will I be using when flying from Guayaquil to Santiago?

    When flying out of Guayaquil you will be using Guayaquil Jose Joaquin de Olmedo. You will be landing at Santiago, also known as Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Guayaquil to Santiago?

    The Airbus A319 is the aircraft model that flies most regularly on the Guayaquil to Santiago flight route.

  • Which airline alliances offer flights from Guayaquil to Santiago?

    Star Alliance is the only airline alliance operating flights between Guayaquil and Santiago.

  • On which days can I fly direct from Guayaquil to Santiago?

    There are nonstop flights from Guayaquil to Santiago on a daily basis.

  • Which is the best airline for flights from Guayaquil to Santiago, LATAM Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Guayaquil to Santiago are LATAM Airlines and Avianca. With an average price for the route of $513 and an overall rating of 7.4, LATAM Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $431 and an overall rating of 6.5.

  • How does KAYAK find such low prices on flights from Guayaquil to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Guayaquil to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Guayaquil to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Guayaquil is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Guayaquil to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Guayaquil with another airline. Booking your flights between Guayaquil and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Guayaquil to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Guayaquil up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Guayaquil to Santiago

  • Looking for a cheap flight? 25% of our users found flights on this route for $243 or less one-way and $431 or less round-trip.

Prefer to fly direct from Guayaquil to Santiago?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez.
Find which airlines fly direct from Guayaquil Jose Joaquin de Olmedo Airport to Santiago Arturo Merino Benitez Airport, which days they fly and book direct flights.

Direct departures

Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez

Monday

LATAM Airlines

LATAM Airlines

Tuesday

LATAM Airlines

LATAM Airlines

Wednesday

LATAM Airlines

LATAM Airlines

Thursday

LATAM Airlines

LATAM Airlines

Friday

LATAM Airlines

LATAM Airlines

Saturday

LATAM Airlines

LATAM Airlines

Sunday

LATAM Airlines

LATAM Airlines

See more direct flights

Direct returns

Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo

Monday

LATAM Airlines

LATAM Airlines

Tuesday

LATAM Airlines

LATAM Airlines

Wednesday

LATAM Airlines

LATAM Airlines

Thursday

LATAM Airlines

LATAM Airlines

Friday

LATAM Airlines

LATAM Airlines

Saturday

LATAM Airlines

LATAM Airlines

Sunday

LATAM Airlines

LATAM Airlines

See more direct flights

Reviews of the top airlines flying from Guayaquil to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Guayaquil to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Guayaquil to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
LATAM AirlinesOverall score based on 1950 reviews
7.3Comfort
6.7Food
7.5Boarding
8.0Crew
7.0Entertainment
Airline reviews

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

10.0 ExcellentSarah, Jan 2026
ANF - SCL
Read more LATAM Airlines reviews

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

I liked everything, this was classed as premium economy but it was much better than Lufthansas business class. Lovely staff, comfortable plane and an excellent seat arrangement. A very pleasant surprise.

The crew was amazing. The best in the last times. Great group of people.

I do not read or speak in Spanish. Only English. When asking for help, the people spoke quickly in English and pointed a lot. I wish they would’ve spoken a little slower for me to understand. There was much confusion and hurried in their message and I was unclear as to where to go

It’s been some time since I saw the plane and the cabin that old and worn out.

I loved how polite the crew was even though some of them wasn't the best with English that they still done everything they could to help me with my needs food was amazing

Terrible They charged me 157$ for excess baggage even though my bags were within the normally accepted limits Flight was late. Service was poor. The snacks were really bad

We do not like to board by shuttle then off the tarmac

A few years ago long flights 6 hours or so used to have video screens and they offered ear phones. The food cart used to come and drinks. Now absolutely nothing. Avianca is as bad as Spirit Airlines. Avianca will now be my last choice when booking my next flight.

Horrible. I have been trying to speak to a representative to know why I was over charged but I get redirected to AI Vianca everytime with no results. Is there an agency that oversees airline gouging? I will never fly or recommend Avianca to anyone not that you care.

They charged for WATER on a SIX hour flight!! never again!

It’s very nice, the only thing is that we have to purchase food.

Avianca flights to Galapagos and back and well organized and on time.

I flew with my service dog unfortunately they didn’t allow it to flight on the canine, but ok, the only problem was that when I arrived to Quito it took 1 hour to deliver my dog, they were supposed to deliver it the moment we get off the airplane.

The worst airline, the crew so mean and rude, everything was a nightmare, if I start to write, I'll never end

Avianca was organized in boarding and disembarking and all announcements were made in both Spanish and English 👍🏼

Horrible service. Flight was delayed and the don't even offer eatwr

Everything you need to know for your flight from Guayaquil to Santiago

Information on your arrival and departure airports