GYE - SCL

$227 Find Cheap Flights from Guayaquil to Santiago - Compare and Save

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Everything you should know

Cheapest round-trip
$447
Typical prices: $430-$561
LATAM Airlines
Thu 2/8Thu 2/15
GYE - SCL • 1 stop
Cheapest non-stop
$470
Typical prices: $480-$612
LATAM Airlines
Mon 12/10Wed 12/19
GYE - SCL • Non-stop
Nonstop flights
You can fly direct with LATAM Airlines. Average duration is 4h 53m
Direct flights
+1
Direct flights
+1
Avoid delays
Most punctual • 91% on-time
Best time • Fewest delays
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 18 weeks in advance save around 19% compared to booking last minute.
Insights
Insights
When to travel
Cheapest • 8% price drop
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Cheapest • Avg $431 (round-trip)
Shortest trip • 8h 48m (one-way)
Insights
Insights
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Guayaquil to Santiago (GYE-SCL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Guayaquil to Santiago

Mon, Feb 8 - Mon, Feb 15
LATAM Airlines Logo
9:05 am - 9:50 pmGYE  Guayaquil Jose Joaquin de Olmedo-SCL Santiago Arturo Merino Benitez
10h 45m1 stop Lima J Chavez Intl
LATAM Airlines Logo
7:05 pm - 1:40 amSCL  Santiago Arturo Merino Benitez-GYE Guayaquil Jose Joaquin de Olmedo
8h 35m1 stop Lima J Chavez Intl
$447LATAM Airlines
Mon, Feb 22 - Tue, Mar 2
Avianca Logo
3:30 am - 3:10 pmGYE  Guayaquil Jose Joaquin de Olmedo-SCL Santiago Arturo Merino Benitez
9h 40m1 stop Bogotá El Dorado
Avianca Logo
7:30 am - 6:25 pmSCL  Santiago Arturo Merino Benitez-GYE Guayaquil Jose Joaquin de Olmedo
12h 55m1 stop Bogotá El Dorado
$448Avianca
Mon, Feb 8 - Mon, Feb 15
LATAM Airlines Logo
9:05 am - 9:50 pmGYE  Guayaquil Jose Joaquin de Olmedo-SCL Santiago Arturo Merino Benitez
10h 45m1 stop Lima J Chavez Intl
LATAM Airlines Logo
7:05 pm - 1:40 amSCL  Santiago Arturo Merino Benitez-GYE Guayaquil Jose Joaquin de Olmedo
8h 35m1 stop Lima J Chavez Intl
$448LATAM Airlines
Sat, Nov 7 - Sun, Nov 15
Avianca Logo
3:30 am - 3:10 pmGYE  Guayaquil Jose Joaquin de Olmedo-SCL Santiago Arturo Merino Benitez
9h 40m1 stop Bogotá El Dorado
Avianca Logo
7:30 am - 3:10 pmSCL  Santiago Arturo Merino Benitez-GYE Guayaquil Jose Joaquin de Olmedo
9h 40m1 stop Bogotá El Dorado
$451Avianca
Tue, Feb 23 - Tue, Mar 2
Avianca Logo
7:35 pm - 3:10 pmGYE  Guayaquil Jose Joaquin de Olmedo-SCL Santiago Arturo Merino Benitez
17h 35m1 stop Bogotá El Dorado
Avianca Logo
7:30 am - 3:10 pmSCL  Santiago Arturo Merino Benitez-GYE Guayaquil Jose Joaquin de Olmedo
9h 40m1 stop Bogotá El Dorado
$451Avianca
Sun, Nov 29 - Sat, Dec 5
LATAM Airlines Logo
9:05 am - 2:50 amGYE  Guayaquil Jose Joaquin de Olmedo-SCL Santiago Arturo Merino Benitez
15h 45m1 stop Lima J Chavez Intl
LATAM Airlines Logo
7:05 pm - 1:40 amSCL  Santiago Arturo Merino Benitez-GYE Guayaquil Jose Joaquin de Olmedo
8h 35m1 stop Lima J Chavez Intl
$452LATAM Airlines
Fri, Feb 26 - Fri, Mar 12
LATAM Airlines Logo
5:28 pm - 12:21 amGYE  Guayaquil Jose Joaquin de Olmedo-SCL Santiago Arturo Merino Benitez
4h 53mnonstop
LATAM Airlines Logo
8:25 pm - 1:40 amSCL  Santiago Arturo Merino Benitez-GYE Guayaquil Jose Joaquin de Olmedo
7h 15m1 stop Lima J Chavez Intl
$452LATAM Airlines
Fri, Mar 26 - Sat, Apr 3
Copa Airlines Logo
6:32 pm - 2:52 pmGYE  Guayaquil Jose Joaquin de Olmedo-SCL Santiago Arturo Merino Benitez
18h 20m1 stop Panama City Tocumen Intl
Copa Airlines Logo
4:06 pm - 10:14 amSCL  Santiago Arturo Merino Benitez-GYE Guayaquil Jose Joaquin de Olmedo
20h 08m1 stop Panama City Tocumen Intl
$475Copa Airlines
Sat, Oct 24 - Tue, Nov 3
Copa Airlines Logo
6:30 pm - 12:22 amGYE  Guayaquil Jose Joaquin de Olmedo-SCL Santiago Arturo Merino Benitez
27h 52m1 stop Panama City Tocumen Intl
Copa Airlines Logo
3:19 am - 11:18 amSCL  Santiago Arturo Merino Benitez-GYE Guayaquil Jose Joaquin de Olmedo
9h 59m1 stop Panama City Tocumen Intl
$475Copa Airlines
Wed, Nov 11 - Thu, Nov 19
Copa Airlines Logo
6:38 pm - 8:15 pmGYE  Guayaquil Jose Joaquin de Olmedo-SCL Santiago Arturo Merino Benitez
23h 37m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:15 pm - 11:18 amSCL  Santiago Arturo Merino Benitez-GYE Guayaquil Jose Joaquin de Olmedo
25h 03m1 stop Panama City Tocumen Intl
$491Copa Airlines
Booking Insights

Price, demand and travel trends for Guayaquil to Santiago flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Guayaquil to Santiago?

Round-trip flights from Guayaquil to Santiago typically range from $430 to $561. The lowest price found in the past 5 days was $447, on LATAM Airlines.

What's the cheapest day of the week to fly from Guayaquil to Santiago?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Guayaquil to Santiago. It’s 3% cheaper than the average day, while Saturday is the most expensive, with prices 4% higher.

What’s the cheapest month to fly from Guayaquil to Santiago?

•November is the cheapest month to fly from Guayaquil to Santiago at $453 round-trip.
•March ($553) and February ($519) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 22% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Guayaquil to Santiago the cheapest?

Flights from Guayaquil to Santiago are cheapest 18 weeks before departure. Booking in this window typically costs about 19% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Key details for Guayaquil to Santiago flights

Low season

June

Cheapest flight

$227
Beat the crowds with an average 37% drop in travelers.
The most popular month to fly with an average 7% increase in travelers.
One-way flight from Guayaquil to Santiago

When to book flights from Guayaquil to Santiago

Are your dates flexible? Find out the best times to travel from Guayaquil to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Guayaquil to Santiago flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What are the earliest and latest flights from Guayaquil to Santiago?

    These are the earliest and latest flight times available from Guayaquil to Santiago:

    • Earliest: departs at 5:24 pm and lands at 10:17 pm
    • Latest: departs at 5:48 pm and lands at 10:41 pm.

    The flight takes about 4h 53m.

  • What cabin classes can I book on flights from Guayaquil to Santiago?

    Three cabin classes are available on flights from Guayaquil to Santiago:

    • Economy Class
    • Premium Economy Class
    • Business Class

  • How long is a flight from Guayaquil to Santiago?

    A nonstop flight from Guayaquil to Santiago takes 4h 53m, covering 2,235 miles.

  • Do I need a passport to fly from Guayaquil to Santiago?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Guayaquil to Santiago flight?

    Round-trip flights from Guayaquil to Santiago range from $430 to $561, with an average of $491 over the past 12 months. Anything below $430 counts as a good deal.

  • How expensive are last-minute Guayaquil to Santiago flights?

    Last-minute fares on this route (booked within two weeks of departure) run 13% above the $491 route average. Book 18 weeks before departure for the lowest fares.

  • How much can I save by taking a layover when flying from Guayaquil to Santiago?

    On this route, layover flights are cheaper than nonstop options on average. Layover fares average $431 round-trip via Bogotá El Dorado (BOG), compared to $534 for nonstop.

  • How does on-time performance compare across airlines flying from Guayaquil to Santiago?

    LATAM Airlines is the only airline operating Guayaquil to Santiago flights. 91% of its flights are on time.

  • What is the standard checked-bag allowance on flights from Guayaquil to Santiago?

    There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $35–$100 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

  • Which aircraft model is used most often on flights from Guayaquil to Santiago?

    The Airbus A319 family is used most often on this route, operated mainly by LATAM Airlines. Other aircraft seen on the route include Airbus A320neo variants.

  • How are flight departures from Guayaquil to Santiago spread across the day?

    Evening is the busiest departure period on Guayaquil to Santiago flights, with 100% of flights leaving in that window. Morning departures account for 0%, afternoon flights for 0%, and night flights for 0%.

  • Have flight prices from Guayaquil to Santiago changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $447 to $3,736. That means the highest observed fare was about 8x higher than the lowest one.

  • How are flight prices from Guayaquil to Santiago looking right now?

    One-way fares from Guayaquil to Santiago are currently lower than usual. Average one-way flight prices are about $249, which is 11% below the typical average for this route.

  • What car rental options are available at Santiago Arturo Merino Benitez Airport (SCL)?

    Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car rental companies, with daily rates starting from around $6 for economy cars. Top options include:

    • Lucano
    • United Rent-A-Car
    • Rosselot
    • FlexWays
    • Alamo

  • Which airports can I use when flying from Guayaquil to Santiago?

    Flights from Guayaquil to Santiago usually depart from Guayaquil Jose Joaquin de Olmedo (GYE) and arrive at Santiago Arturo Merino Benitez (SCL).

  • What time of day has the fewest delays on flights from Guayaquil to Santiago?

    Afternoon flights have the fewest delays on this route.

  • At what point is a flight considered delayed from Guayaquil to Santiago?

    A flight is considered delayed when it departs 15 minutes or more after its scheduled time. This is the standard used by the US Department of Transportation and most airline industry reporting. On the Guayaquil to Santiago route, 9% of flights were delayed in the past 3 months, with delays averaging 2h 05m.

  • Which airports do connecting flights from Guayaquil to Santiago pass through?

    One-stop flights from Guayaquil to Santiago most commonly connect through:

    • Bogotá El Dorado (BOG) - 53% of one-stop connections
    • Lima J Chavez Intl (LIM) - 43% of one-stop connections
    • Panama City Tocumen Intl (PTY) - 4% of one-stop connections

  • Can I save money by using flexible dates for flights from Guayaquil to Santiago?

    Yes. Flexible dates can save you up to 7% on flights from Guayaquil to Santiago. Tuesday is the cheapest departure day at $481 round-trip on average, while Saturday is the most expensive at $512, a difference of $31.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What airlines fly from Guayaquil to Santiago?

    Only LATAM Airlines operates flights between Guayaquil and Santiago.

  • How much time can I save by choosing a different layover airport from Guayaquil to Santiago?

    Flying via Lima J Chavez Intl (LIM) gives the shortest average 1-stop total travel time at 8h 48m, compared with 10h 33m via Bogotá El Dorado (BOG) and 11h 08m via Panama City Tocumen Intl (PTY).

  • What is the time difference between Guayaquil and Santiago?

    Santiago is 2 hours ahead of Guayaquil (Chile Time vs Ecuador Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Santiago?

    Some of the most popular sights in Santiago are Estadio Nacional Julio Martinez Pradanos, Espacio Riesco Convention and Exhibition Center and Costanera Center. These are among the most viewed places in Santiago on KAYAK.

  • Which airlines offer extra legroom and free seat selection on Guayaquil to Santiago flights?

    Among airlines operating Guayaquil to Santiago flights:

    • LATAM Airlines: offers extra legroom; offers free seat selection

    Extra legroom and free seat selection availability depends on fare class and route.

  • Which airlines include bags at no extra cost on Guayaquil to Santiago flights?

    Here are some options for this route, based on selected ticket types and cabin classes:

    • LATAM Airlines: a cabin bag and a checked bag in Economy Class

    Bag allowance can vary by ticket type, cabin class, route and airline, so always check the fare details before booking.

Your guide to booking Guayaquil to Santiago flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Saturday. On this route, Tuesday flights average $481, about $31 less than Saturday fares (6% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 18 weeks before you fly. On this route, that window historically saves about 19% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Guayaquil to Santiago trip for November. Fares historically average $453 round-trip in that month - typically $100 less than the most expensive month, which is March (based on the last 12 months).
  • If you have the time, taking a 1-stop flight through Bogotá El Dorado Airport (BOG) can be cheaper than flying direct. The cheapest layover option averages $431 round-trip on this route - about $103 less than direct flights (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santiago Arturo Merino Benitez Airport.

    • Holiday Inn Santiago - Airport Terminal By IHG

Prefer to fly direct from Guayaquil to Santiago?

 
Find which airlines fly direct from Guayaquil Jose Joaquin de Olmedo Airport to Santiago Arturo Merino Benitez Airport, which days they fly and book direct flights.

Direct departures

Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez

Monday

LATAM Airlines

LATAM Airlines

Tuesday

LATAM Airlines

LATAM Airlines

Wednesday

LATAM Airlines

LATAM Airlines

Thursday

LATAM Airlines

LATAM Airlines

Friday

LATAM Airlines

LATAM Airlines

Saturday

LATAM Airlines

LATAM Airlines

Sunday

LATAM Airlines

LATAM Airlines

See more direct flights

Direct returns

Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo

Monday

LATAM Airlines

LATAM Airlines

Tuesday

LATAM Airlines

LATAM Airlines

Wednesday

LATAM Airlines

LATAM Airlines

Thursday

LATAM Airlines

LATAM Airlines

Friday

LATAM Airlines

LATAM Airlines

Saturday

LATAM Airlines

LATAM Airlines

Sunday

LATAM Airlines

LATAM Airlines

See more direct flights

More options for your flight from Guayaquil to Santiago

Complete your trip to Santiago with a hotel stay or car rental