GYE - SCL

$214 Find Cheap Flights from Guayaquil to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Guayaquil to Santiago departing on 12/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Guayaquil to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Guayaquil to Santiago, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$408
Overall average: $459
Multiple Airlines
Mon 1/12Thu 1/29
GYE - SCL • 1 stop
Cheapest non-stop
$479
Typical prices: $287-$532
LATAM Airlines
Mon 5/18Thu 5/21
GYE - SCL • Non-stop
When to book
10 weeks
in advance
Our data shows that travelers who book at least 10 weeks in advance save around 6% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
April
Cheapest • 6% price drop
March
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Guayaquil to Santiago (GYE-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Guayaquil to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Guayaquil to Santiago

Mon, Jan 12 - Thu, Jan 29
Multiple Airlines Logo
3:30 am - 3:20 pm
GYE
-
SCL
9h 50m1 stop
Multiple Airlines Logo
4:15 pm - 1:40 am
SCL
-
GYE
11h 25m1 stop
$408Multiple Airlines
Wed, Dec 24 - Fri, Mar 20
Copa Airlines Logo
12:20 pm - 3:43 am
GYE
-
SCL
13h 23m1 stop
Copa Airlines Logo
5:21 am - 11:55 pm
SCL
-
GYE
20h 34m1 stop
$409Copa Airlines
Mon, Apr 13 - Sat, Apr 18
Multiple Airlines Logo
8:45 pm - 5:45 am
GYE
-
SCL
8h 00m1 stop
Multiple Airlines Logo
2:30 pm - 10:40 pm
SCL
-
GYE
9h 10m1 stop
$414Multiple Airlines
Tue, Jan 13 - Thu, Jan 29
Multiple Airlines Logo
10:25 am - 12:30 am
GYE
-
SCL
12h 05m1 stop
Multiple Airlines Logo
10:15 pm - 2:22 pm
SCL
-
GYE
18h 07m2 stops
$429Multiple Airlines
Sun, Mar 22 - Sun, Apr 12
Avianca Logo
9:05 am - 12:30 am
GYE
-
SCL
13h 25m1 stop
Avianca Logo
6:10 am - 5:20 pm
SCL
-
GYE
12h 10m1 stop
$431Avianca
Mon, Mar 23 - Sat, Mar 28
Multiple Airlines Logo
6:55 pm - 3:20 pm
GYE
-
SCL
18h 25m1 stop
Multiple Airlines Logo
8:50 am - 2:45 pm
SCL
-
GYE
7h 55m1 stop
$438Multiple Airlines
Wed, Feb 11 - Mon, Feb 16
Multiple Airlines Logo
6:55 pm - 3:20 pm
GYE
-
SCL
18h 25m1 stop
Multiple Airlines Logo
6:30 pm - 1:40 am
SCL
-
GYE
9h 10m1 stop
$441Multiple Airlines
Wed, Jan 14 - Thu, Jan 29
Multiple Airlines Logo
10:25 am - 12:30 am
GYE
-
SCL
12h 05m1 stop
Multiple Airlines Logo
4:15 pm - 1:40 am
SCL
-
GYE
11h 25m1 stop
$443Multiple Airlines
Thu, Jan 15 - Thu, Jan 29
Multiple Airlines Logo
6:55 pm - 3:20 pm
GYE
-
SCL
18h 25m1 stop
Multiple Airlines Logo
4:15 pm - 1:40 am
SCL
-
GYE
11h 25m1 stop
$444Multiple Airlines
Sun, Mar 22 - Sun, Apr 12
Avianca Logo
10:25 am - 5:30 am
GYE
-
SCL
17h 05m1 stop
Avianca Logo
6:10 am - 9:33 pm
SCL
-
GYE
16h 23m2 stops
$451Avianca
Booking Insights

KAYAK's insights & trends for Guayaquil to Santiago flights

Get data-powered insights and trends into flights from Guayaquil to Santiago to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Guayaquil to Santiago?

The average price of all round-trip flights from Guayaquil to Santiago clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Santiago on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Saturday is the most expensive day to fly from Guayaquil to Santiago. For your return ticket, we recommend flying on a Thursday and avoiding Sundays for the best deals.

What is the cheapest month to fly from Guayaquil to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Guayaquil to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Guayaquil to Santiago is April, where tickets cost $407 (return) on average. On the other hand, the most expensive months are February and January, where the average cost of round-trip tickets is $467 and $459 respectively.

How far in advance should I book a flight from Guayaquil to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Guayaquil to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Guayaquil to Santiago, you should book around 10 weeks before departure, which saves you about 6% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 18 weeks before departure.

Good to know

Low seasonJuly
Cheapest flight$214
Best time to beat the crowds with an average 1% drop in price.
Most popular time to fly and prices are also 1% lower on average.
Flight from Guayaquil to Santiago

When to book flights from Guayaquil to Santiago

Are your dates flexible? Find out the best times to travel from Guayaquil to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Guayaquil to Santiago

  • What is the cheapest flight from Guayaquil to Santiago?

    In the last 3 days, the lowest price for a flight from Guayaquil to Santiago was $214 for a one-way ticket and $408 for a round-trip.

  • Do I need a passport to fly between Guayaquil and Santiago?

    Yes

  • Which airports will I be using when flying from Guayaquil to Santiago?

    When flying out of Guayaquil you will be using Guayaquil Jose Joaquin de Olmedo. You will be landing at Santiago, also known as Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Guayaquil to Santiago?

    The Airbus A319 is the aircraft model that flies most regularly on the Guayaquil to Santiago flight route.

  • Which airline alliances offer flights from Guayaquil to Santiago?

    Star Alliance is the only airline alliance operating flights between Guayaquil and Santiago.

  • On which days can I fly direct from Guayaquil to Santiago?

    There are nonstop flights from Guayaquil to Santiago on a daily basis.

  • Which is the best airline for flights from Guayaquil to Santiago, Copa Airlines or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Guayaquil to Santiago are Copa Airlines and LATAM Airlines. With an average price for the route of $262 and an overall rating of 7.6, Copa Airlines is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $503 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Guayaquil to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Guayaquil to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Guayaquil to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Guayaquil is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Guayaquil to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Guayaquil with another airline. Booking your flights between Guayaquil and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Guayaquil to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Guayaquil up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Guayaquil to Santiago

  • Looking for a cheap flight? 25% of our users found flights on this route for $260 or less one-way and $568 or less round-trip.

Prefer to fly direct from Guayaquil to Santiago?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez.
Find which airlines fly direct from Guayaquil Jose Joaquin de Olmedo Airport to Santiago Arturo Merino Benitez Airport, which days they fly and book direct flights.

Direct departures

Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez

Monday

LATAM Airlines

LATAM Airlines

Tuesday

LATAM Airlines

LATAM Airlines

Wednesday

LATAM Airlines

LATAM Airlines

Thursday

LATAM Airlines

LATAM Airlines

Friday

LATAM Airlines

LATAM Airlines

Saturday

LATAM Airlines

LATAM Airlines

Sunday

LATAM Airlines

LATAM Airlines

See more direct flights

Direct returns

Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo

Monday

LATAM Airlines

LATAM Airlines

Tuesday

LATAM Airlines

LATAM Airlines

Wednesday

LATAM Airlines

LATAM Airlines

Thursday

LATAM Airlines

LATAM Airlines

Friday

LATAM Airlines

LATAM Airlines

Saturday

LATAM Airlines

LATAM Airlines

Sunday

LATAM Airlines

LATAM Airlines

See more direct flights

Reviews of the top 3 airlines serving from Guayaquil to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Guayaquil to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Guayaquil to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1554 reviews
7.4Comfort
7.8Boarding
8.1Crew
6.9Food
6.8Entertainment
Airline reviews

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

6.0 GoodZach, Oct 2025
DEN - PTY
Read more Copa Airlines reviews

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Some of the Air hostesses are not that friendly. Need improvement

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

Great experience with a crew always thinking in the passenger

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

I selected first class expecting excetional service. It was mediocre at best. The food service was cold, meal choices was poor and on one leg they did provide dessert. I did enjoy the lay day seat but the movies were old and nothing current. Boarding the plane is always hot. So boarding is quite warm until your in the air. I took a small personal air fan. Update the meals and movies.

Did upgrade, travel in business it was great (more room I could sleep)

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

It was ok. However, the food was quite poor since I don't eat pasta.

Good flight, boarding ok and crew very nice. Flight was not full so I was able to be very comfortable. Blanket and pillow provided with was good as it was very cold during the flight . Food was very good(small snack sandwich and an excellent piece of orange cake). Overall good flight, no complaints.

I like this airline a lot no problems at all, except being forced to check a carry-on bag ., Overall very good airline

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Poor, the airline was not able to help me move flights.

Check in -- in business took over 30 mins as there was only one attendant. Boarding was also a mess. The seat was too narrow and was not working properly. Food was very bad and the entertainment very poor. Crew was very polite and helpful, in fairness.

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

Really bad experience – delayed for 6 hours without any notice, no food or drinks provided, and stuck in the horrible Cartagena airport.

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

I like the crew members they're very friendly. Clean plane. The flight was on time. I dont like the comfort my car seat its better that the plane seats. They charge for everything. This airline was very good. Now it's a low cost airline

No free snacks nor drinks on very short 30min flight. Entertainment system is over wifi to your own phone or tablet, which is good but often a show or movie just stops and refuses to continue

Not even water is offered on the flight. You cannot lean back on the seats and the seats are so narrow you can’t avoid rubbing elbows with the person next to you.

Horrible experience. Flight cancelled. Arrived at destination 12 hs later. No one gave us an answer or any information. Very very poor service. We won’t ever travel again with Avianca

The usb plugs for charging your phone didn’t work, the seats were coarse and hard. Not very comfortable. No inflight WiFi

No food, terms when selling are not clear. To pricy for the service in general

It was horrible. My experience with Avianca. I didn’t know it was Pakistan international Airlines but anyway, whatever it is it is bad horrible you guys need to upgrade everything in those planes. And you guys charge $130 for a carry-on did they wanna let me in with my carry-on that I travel everywhere with the luggage you guys are such a dog thank you

why did we have to go through security mid flight

Boarding was excessively slow. They do it by groups in a way that it doesn’t make sense. After business class , ppl that need assistance and any other priority group they should have ppl board from the back to the front. First rows 20+. Then 15+. Then 10, etc. having ppl sitting in the back board last makes no sense. The libe backame long as soon as ppl on rows 10 or so where told to board. The line went all the way up the ramp and tunnel for 25 mins.

Flight to Bogotá delayed by 3 h Missed connection from Bogotá to Guayaquil. Avianca unable to bring us to Baltra on time Overall delay 36h. We missed boat departure from galagos. Overall 10 day trip needed to be cancelled. Avianca was completely un-professional.

Everything you need to know for your flight from Guayaquil to Santiago

Information on your arrival and departure airports