$953 Find Cheap Flights from Santiago to Missouri

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to Missouri departing on 6/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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KAYAK searches hundreds of travel sites at once for deals on flights to Missouri

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Missouri, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Missouri, as well as popular online travel agencies
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Flights Deals

Best Missouri Flight Deals from Santiago

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

St. Louis
St. Louis2 stops$953
Kansas City
Kansas City3 stops$771
St. Louis
St. Louis2 stops$953
Kansas City
Kansas City3 stops$771

Cheap Flight Deals from Santiago to Missouri (SCL-USMO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to Missouri that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Santiago to Missouri

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from Santiago to Missouri.
Discover the best prices for you by selecting your travel dates on KAYAK.
American Airlines Logo
9:55 pm - 7:15 pmSCL-STL
22h 20m2 stops
American Airlines Logo
10:08 am - 7:05 amSTL-SCL
19h 57m2 stops
$953American Airlines
Find Deal
Thu, Jun 5 - Mon, Aug 25
American Airlines Logo
9:55 pm - 2:19 pmSCL-STL
17h 24m2 stops
American Airlines Logo
5:18 am - 7:05 amSTL-SCL
24h 47m1 stop
$964American Airlines
Find Deal
Thu, Jun 5 - Mon, Aug 25
American Airlines Logo
9:55 pm - 11:59 pmSCL-STL
27h 04m1 stop
American Airlines Logo
5:25 am - 7:00 amSTL-SCL
24h 35m1 stop
$1,017American Airlines
Find Deal
Tue, Jun 17 - Tue, Jun 24
Delta Logo
8:40 pm - 12:35 pmSCL-STL
16h 55m1 stop
Delta Logo
9:28 am - 6:30 amSTL-SCL
20h 02m2 stops
$1,020Delta
Find Deal
Tue, Jun 17 - Tue, Jun 24
 Logo
6:10 am - 12:36 pmSCL-STL
31h 26m3 stops
 Logo
1:30 pm - 1:25 pmSTL-SCL
22h 55m3 stops
$1,152
Find Deal
Tue, Jun 17 - Tue, Jun 24
 Logo
6:10 am - 12:36 pmSCL-STL
31h 26m3 stops
 Logo
7:30 am - 1:25 pmSTL-SCL
28h 55m2 stops
$1,157
Find Deal
Tue, Jun 17 - Tue, Jun 24
LATAM Airlines Logo
11:25 pm - 6:01 pmSCL-STL
19h 36m2 stops
LATAM Airlines Logo
3:30 pm - 12:35 pmSTL-SCL
20h 05m3 stops
$1,258LATAM Airlines
Find Deal
Thu, Jun 5 - Mon, Aug 25
 Logo
1:55 am - 12:36 pmSCL-STL
35h 41m3 stops
 Logo
6:30 am - 1:25 pmSTL-SCL
29h 55m3 stops
$1,511
Find Deal
Mon, Jun 16 - Tue, Jun 24
Copa Airlines Logo
2:24 am - 9:56 amSCL-STL
32h 32m2 stops
Copa Airlines Logo
8:10 am - 5:04 amSTL-SCL
19h 54m2 stops
$1,739Copa Airlines
Find Deal
Wed, Jun 4 - Mon, Aug 25
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KAYAK's insights & trends for Santiago to Missouri flights

Get data-powered insights and trends into flights from Santiago to Missouri to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Santiago to Missouri?

The average price of all round-trip flights from Santiago to Missouri clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Santiago to Missouri, look for departures on Tuesdays and avoid leaving on a Friday, as it's usually the priciest day. When flying back from Missouri, Wednesday is the cheapest day to fly and Saturday is the most expensive.


Good to know

Low seasonApril
High seasonJune
Cheapest flight$953
Best time to beat the crowds but there is an average 5% increase in price.
Most popular time to fly with an average 15% increase in price.
Flight from Santiago to St. Louis

FAQs - booking Missouri flights

  • How does KAYAK find such low prices on flights from Santiago to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Santiago to Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Santiago to Missouri with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Santiago to Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Missouri?

    The cheapest time of day to fly to Missouri is generally at night, when round-trip flights cost $889 on average. The most expensive time of day to fly to Missouri is generally at night, which is peak travel time and where the average cost of a ticket is $889.

Top 3 airlines serving from Santiago to Missouri

 
See real verified KAYAK customer reviews for airlines flying from Santiago to Missouri. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7937 reviews
7.3Food
7.9Comfort
8.2Boarding
8.5Crew
7.9Entertainment
Airline reviews

Food from the flight from Atlanta to Santiago was very poor..

4.0 OkayAnonymous, May 2025FAI - SEA
Read more Delta reviews

Food from the flight from Atlanta to Santiago was very poor..

Flight was delayed due to weather. Crew did a nice job of making us comfortable. No complain complaints.

Fine except the person next to me took up her seat had raised the arm divide so she spilled into my seat. because of her size. Fortunately no one was in the seat on my right so I could use part of it.

Delta is my preferred airline. I've traveled with them for years. On time in most cases, good communication, easy to use app. Most planes are pretty nice. I was on a CRJ 700/900 however, which was pretty badly aged inside and needed a refresh. No infotainment, unreliable wifi, best to download before boarding or bring a book. Food choices are really just snacks on this flight, nice variety but about what you'd expect. Great staff and prompt in departure and early arrival too. Overall quite satisfied.

Crew was friendly Love the entertainment in the seat head rest.

Delta flight was on time, seats were comfortable, and crew was nice.

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

Delayed take-off. Very small plane so very scary with lots of bumps during the flight. Would never fly Delta on short flights in small 80 seaters plane again! Felt relieved when landed.

Delta is a cut above the others in customer service.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

I travel often with LATAM, it never disappoints me. The service is great, nice crew, latest and some classic movies. I got 3 small meals, cannot complaint. I’ll definitely travel again with them.

It was good, however the airplane was really cold. We received snacks and the crew was friendly.

Delta has an outstanding service. They are courteous and punctual most of the time. The flight departed a half hour late but we arrived 15 minutes early.

Not sure why there are so many security checks at this airport. Consistently annoying showing passport over and over, checking carryons at gate all the while trying to make tight connection. Basically it was uncomfortable crowded cabin with meidiocre service

Change of gate in Santiago devolved into half plus hour delay and a really tight connection in Lima

Although the flight is goof and the crew is good, the way the airline charges you for every service is ridiculous.

Plane never left the ground. Mech issues - entire trip was rerouted through united.

They didi not provide wheelchair though we had requested. We had to run around for 40 minutes and arrange it from the airport!

I liked everything, this was classed as premium economy but it was much better than Lufthansas business class. Lovely staff, comfortable plane and an excellent seat arrangement. A very pleasant surprise.

Everything was good except the check in. Could not do it online neither on the machines in the airport. Needed special assistance from the airline desk clerk

In flight connectivity (via T-Mobile) was often not working.

Seats were roomy. Lavatories were surprisingly big and clean. Plenty of entertainment available. We were fed and offered drinks, multiple times during the flight.

Pitch was very small. Knees were on the seat back in front of me.

Paid $35 and not able to access the internet at all.

Several delays. Next flight was worse. Did not arrive home until 2am PT

Very helpful ground crew after an earlier flight delay and being rebooked on a different flight.

Everything about the flight was lovely…We left early, arrived early, cabin crew were efficient and helpful. Flight was easy and most pleasant.

First world problems, but still… We were seated in first class and asked for a cocktail on a very short, 50 minute flight. After our drink order was taken, a half hour went by, and we noticed that every other person in the small plane had been served except for us. We got up to ask about it, the drinks finally came, then were taken away three minutes later since the flight was so short. Really strange situation, on the other hand, we were in Utah.

We missed our flight. The boarding pass had the wrong gate and by the time we received the text from Kayak, our flight was already gone. I’ll never use Kayak again and will go direct to the airlines in the future.

Boarding took forever, the plane was cramped and cold, and the seatbelt song came on constantly throughout the red eye flight with a loud pre-recorded message playing each time

Everything you need to know for your flight from Santiago to Missouri

Information on your arrival and departure airports

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