SCL - STL

$524 Find Cheap Flights from Santiago to St. Louis

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to St. Louis departing on 11/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to St. Louis, as well as popular online travel agencies
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Flights Deals

Cheap Flights from Santiago to St. Louis (SCL-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to St. Louis

Sun, Jul 6 - Wed, Aug 6
 Logo
11:30 am - 6:18 pmSCL-STL
31h 48m3 stops
 Logo
11:24 am - 4:15 amSTL-SCL
15h 51m2 stops
Sun, Jul 6 - Wed, Aug 6
 Logo
11:30 am - 6:18 pmSCL-STL
31h 48m3 stops
 Logo
11:24 am - 9:15 pmSTL-SCL
32h 51m3 stops
Wed, Jul 9 - Tue, Sep 9
American Airlines Logo
9:50 pm - 7:14 pmSCL-STL
22h 24m2 stops
American Airlines Logo
10:54 am - 8:05 amSTL-SCL
19h 11m2 stops
$1,058American Airlines
Find Deal
Sun, Jul 6 - Wed, Aug 6
American Airlines Logo
9:50 pm - 11:57 pmSCL-STL
27h 07m1 stop
American Airlines Logo
5:26 am - 6:55 amSTL-SCL
24h 29m1 stop
$1,068American Airlines
Find Deal
Wed, Jul 9 - Tue, Sep 9
American Airlines Logo
9:50 pm - 4:22 pmSCL-STL
19h 32m2 stops
American Airlines Logo
5:28 am - 8:05 amSTL-SCL
24h 37m1 stop
$1,070American Airlines
Find Deal
Tue, Jul 8 - Mon, Jul 14
Delta Logo
8:40 pm - 12:34 pmSCL-STL
16h 54m1 stop
Delta Logo
5:23 pm - 7:00 amSTL-SCL
12h 37m1 stop
$1,110Delta
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Tue, Jul 8 - Tue, Sep 9
LATAM Airlines Logo
12:37 am - 11:53 pmSCL-STL
24h 16m2 stops
LATAM Airlines Logo
5:11 pm - 7:00 amSTL-SCL
11h 49m1 stop
$1,169LATAM Airlines
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Fri, Jun 27 - Tue, Jul 15
Delta Logo
8:40 pm - 11:36 pmSCL-STL
27h 56m1 stop
Delta Logo
5:23 pm - 7:00 amSTL-SCL
12h 37m1 stop
$1,190Delta
Find Deal
Sat, Jul 5 - Wed, Aug 6
LATAM Airlines Logo
12:37 am - 11:51 pmSCL-STL
24h 14m2 stops
LATAM Airlines Logo
5:23 pm - 12:25 pmSTL-SCL
18h 02m2 stops
$1,201LATAM Airlines
Find Deal
Tue, Jul 8 - Tue, Sep 9
Copa Airlines Logo
2:23 am - 9:59 amSCL-STL
32h 36m2 stops
Copa Airlines Logo
8:15 am - 6:00 amSTL-SCL
19h 45m2 stops
$4,041Copa Airlines
Find Deal
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KAYAK's insights & trends for Santiago to St. Louis flights

Get data-powered insights and trends into flights from Santiago to St. Louis to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Santiago to St. Louis?

The average price of all round-trip flights from Santiago to St. Louis clicked on KAYAK for each day over the last 12 months.

When flying from Santiago to St. Louis, you should consider leaving on a Tuesday and avoid Fridays if you are looking for the best rates. For your return to Santiago, you’ll find the best rates on Wednesdays and the most expensive ones on Saturdays.

Good to know

Low seasonNovember
High seasonAugust
Cheapest flight$524
Best time to beat the crowds with an average 21% drop in price.
Most popular time to fly with an average 2% increase in price.
Flight from Santiago to St. Louis

When to book flights from Santiago to St. Louis

Are your dates flexible? Find out the best times to travel from Santiago to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santiago to St. Louis

  • What is the cheapest flight from Santiago to St. Louis?

    In the last 3 days, the lowest price for a flight from Santiago to St. Louis was $524 for a one-way ticket and $931 for a round-trip.

  • Do I need a passport to fly between Santiago and St. Louis?

    Yes

  • Which aircraft models fly most regularly from Santiago to St. Louis?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santiago to St. Louis?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between Santiago and St. Louis, with Star Alliance being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from Santiago to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Santiago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Santiago with another airline. Booking your flights between Santiago and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Santiago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Santiago to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Santiago to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7963 reviews
7.3Food
8.2Boarding
7.9Comfort
8.5Crew
7.9Entertainment
Airline reviews

I like for how they process during check in. It was very smoothly.

10.0 ExcellentAbdulla, Jun 2025CMH - JFK
Read more Delta reviews

I like for how they process during check in. It was very smoothly.

The flight was scheduled for 2:30 PM. Early in the morning we got a text message saying the flight was delayed and rescheduled for 3:00 PM. We got to the airport with that in mind. Then we got a message during check-in at the flight was rescheduled again for 2:30 PM. We almost missed our flight. In fact, our bags Were told that they would not make it. At the end, everything worked out. But it is very stressful.

Most aspects were good however if they assign boarding zones they ought to enforce them or why bother? My luggage from SAN-JFK-MAD was lost in NY so I without my main bag for two days upon arrival in Spain. They were helpful in tracking it and eventually delivered it to my hotel. The flub was because of a delay upon arrival in NYC. I had booked 2 1/2 hours between flights but we had to hold on the taxiway for an hour after landing while waiting for a clear gate which likely caused the baggage error.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Great overall. There was a bit of turbulence so they could only serve water because too much turbulence for the carts. Was glad they prioritized safety though

Excellent flight, the planes were newer, they did a nice job with boarding, great service overall.

Great service. Flight was delayed while we sat on the runway for a couple of hours. Weather related. Staff made is very bearable. The steward servicing the first class cabin was exceptional. Thank you! 💗

5 hours of delay that could've been much shorter if Delta had taken the 1 hour delay they imposed on the flight before boarding to run any of the plane checks required for flight to find the hydraulic issue that required nearly 3 hours to fix. $24 of meal credit buys a sandwich and a soft drink. Poor communication within the terminal about what gate we'd be re-boarding from and when we'd be re-boarding.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

It would be nice if was given wires ear buds. Overall was a good experience was able to sleep on the plane

Everything you need to know for your flight from Santiago to St. Louis

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