SCL - STL

$461 Find Cheap Flights from Santiago to St. Louis

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to St. Louis departing on 8/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to St. Louis, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$890
Typical prices: $1,159-$1,024
Multiple Airlines
Mon 6/8Tue 6/16
SCL - STL • 2 stops
Cheapest one-way
$461
Multiple Airlines
Thu 8/27
SCL - STL • 3 stops
Top airlines
LATAM Airlines
Cheapest • from $1,016 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Santiago and St. Louis. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Dallas (DFW)
Cheapest • Avg $1,130 (round-trip)
Atlanta (ATL)
Shortest trip • 14h 03m (one-way)
Insights
Insights
Insights
Insights
When to travel
December
Cheapest • 19% price drop
May
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to St. Louis!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santiago to St. Louis (SCL-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to St. Louis

Mon, Jun 8 - Tue, Jun 16
Multiple Airlines Logo
2:51 am - 12:09 am
SCL
-
STL
22h 18m
2 stops
Multiple Airlines Logo
6:31 pm - 1:35 pm
STL
-
SCL
42h 04m
3 stops
$890Multiple Airlines
Thu, Jun 11 - Thu, Jun 18
Multiple Airlines Logo
4:09 am - 12:09 am
SCL
-
STL
45h 00m
2 stops
Multiple Airlines Logo
6:31 pm - 1:35 pm
STL
-
SCL
42h 04m
3 stops
$918Multiple Airlines
Tue, Jun 30 - Wed, Jul 8
Multiple Airlines Logo
12:43 am - 12:09 am
SCL
-
STL
24h 26m
2 stops
Multiple Airlines Logo
4:09 pm - 1:25 pm
STL
-
SCL
44h 16m
3 stops
$937Multiple Airlines
Thu, Jun 11 - Thu, Jun 18
Multiple Airlines Logo
4:09 am - 12:09 am
SCL
-
STL
45h 00m
2 stops
Multiple Airlines Logo
4:17 pm - 1:35 pm
STL
-
SCL
44h 18m
2 stops
$945Multiple Airlines
Tue, Jun 30 - Wed, Jul 8
Multiple Airlines Logo
2:27 am - 12:09 am
SCL
-
STL
22h 42m
2 stops
Multiple Airlines Logo
4:09 pm - 1:25 pm
STL
-
SCL
44h 16m
3 stops
$958Multiple Airlines
Tue, Jun 30 - Wed, Jul 8
Multiple Airlines Logo
2:56 am - 12:09 am
SCL
-
STL
22h 13m
2 stops
Multiple Airlines Logo
4:09 pm - 1:25 pm
STL
-
SCL
44h 16m
3 stops
$994Multiple Airlines
Thu, Jun 11 - Thu, Jun 18
Multiple Airlines Logo
4:09 am - 12:09 am
SCL
-
STL
45h 00m
2 stops
Multiple Airlines Logo
6:31 pm - 1:35 pm
STL
-
SCL
42h 04m
3 stops
$1,010Multiple Airlines
Wed, Jul 1 - Wed, Jul 8
LATAM Airlines Logo
11:05 pm - 6:07 pm
SCL
-
STL
20h 02m
2 stops
LATAM Airlines Logo
1:22 pm - 6:55 am
STL
-
SCL
16h 33m
2 stops
$1,016LATAM Airlines
Tue, Jul 14 - Wed, Aug 5
Multiple Airlines Logo
12:43 am - 7:23 pm
SCL
-
STL
43h 40m
3 stops
Multiple Airlines Logo
4:09 pm - 6:55 am
STL
-
SCL
37h 46m
3 stops
$1,017Multiple Airlines
Tue, Jul 14 - Wed, Aug 5
Multiple Airlines Logo
12:43 am - 7:23 pm
SCL
-
STL
43h 40m
3 stops
Multiple Airlines Logo
4:09 pm - 6:55 am
STL
-
SCL
37h 46m
3 stops
$1,018Multiple Airlines
Booking Insights

KAYAK's insights & trends for Santiago to St. Louis flights

Get data-powered insights and trends into flights from Santiago to St. Louis to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santiago to St. Louis?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santiago to St. Louis departing in June.

What is the cheapest month to fly from Santiago to St. Louis?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santiago to St. Louis, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santiago to St. Louis is December, where tickets cost $795 (return) on average. On the other hand, the most expensive months are May and January, where the average cost of round-trip tickets is $1,222 and $1,150 respectively.

Find deals

Good to know

Low seasonOctober
Cheapest flight$461
Best time to beat the crowds with an average 11% drop in price.
Most popular time to fly with an average 24% increase in price.
Flight from Santiago to St. Louis

When to book flights from Santiago to St. Louis

Are your dates flexible? Find out the best times to travel from Santiago to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santiago to St. Louis

  • What is the cheapest flight from Santiago to St. Louis?

    In the last 3 days, the lowest price for a flight from Santiago to St. Louis was $461 for a one-way ticket and $890 for a round-trip.

  • Do I need a passport to fly between Santiago and St. Louis?

    Yes

  • Which aircraft models fly most regularly from Santiago to St. Louis?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santiago to St. Louis?

    SkyTeam is the only airline alliance operating flights between Santiago and St. Louis.

  • How does KAYAK find such low prices on flights from Santiago to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Santiago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Santiago with another airline. Booking your flights between Santiago and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Santiago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Santiago to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Santiago to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8464 reviews
7.9Comfort
8.1Boarding
7.8Entertainment
8.5Crew
7.2Food
Airline reviews

Round trip flight to Canada and back to the US was smooth and efficient.

8.0 ExcellentBrent, Apr 2026
YWG - MSP
Read more Delta reviews

Round trip flight to Canada and back to the US was smooth and efficient.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

Spanish speaker flight attendants were incredibly rude. A male flight attendant named Allen, grabbed my bag out of the overhead bin and moved it without my permission. When I asked what he was doing, he informed me that the overhead bins were public space? It would be easy to ignore this comment, as you don’t know the whole story, but the flight attendants were militant and rude. Delta, you can do better!

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

Very easy to use and convenient, you can perform any action within the same portal

In a world of delays, Delta was on time both ways! Boarding was fast and efficient. Staff was friendly. AND wifi worked.

My business class seat was inoperable and unable to recline for 10 hour flight.

Everything you need to know for your flight from Santiago to St. Louis

Information on your arrival and departure airports

Santiago (SCL)
St. Louis (STL)