SCL - STL

$310 Find Cheap Flights from Santiago to St. Louis

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to St. Louis departing on 4/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to St. Louis, as well as popular online travel agencies
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41 299 237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$878
Typical prices: $840-$1,075
LATAM Airlines
Wed 7/15Wed 8/5
SCL - STL • 2 stops
Cheapest one-way
$310
Multiple Airlines
Fri 4/24
SCL - STL • 3 stops
Top airlines
Cheapest • from $878 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Santiago and St. Louis. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $1,130 (round-trip)
Shortest trip • 14h 00m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 19% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to St. Louis!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santiago to St. Louis (SCL-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to St. Louis

Wed, Jul 15 - Wed, Aug 5
LATAM Airlines Logo
11:00 pm - 6:02 pm
SCL
-
STL
20h 02m
2 stops
LATAM Airlines Logo
1:30 pm - 6:55 am
STL
-
SCL
16h 25m
2 stops
$878LATAM Airlines
Wed, Jul 15 - Wed, Aug 5
LATAM Airlines Logo
8:40 pm - 10:45 am
SCL
-
STL
15h 05m
1 stop
LATAM Airlines Logo
1:30 pm - 6:55 am
STL
-
SCL
16h 25m
2 stops
$898LATAM Airlines
Wed, Jul 15 - Wed, Aug 5
American Airlines Logo
8:30 pm - 10:24 am
SCL
-
STL
14h 54m
1 stop
American Airlines Logo
11:48 am - 6:50 am
STL
-
SCL
18h 02m
1 stop
$913American Airlines
Wed, Jul 15 - Wed, Aug 5
American Airlines Logo
8:30 pm - 10:24 am
SCL
-
STL
14h 54m
1 stop
American Airlines Logo
5:18 am - 6:50 am
STL
-
SCL
24h 32m
1 stop
$915American Airlines
Wed, Jul 15 - Wed, Aug 5
Delta Logo
11:05 pm - 6:02 pm
SCL
-
STL
19h 57m
2 stops
Delta Logo
3:42 pm - 7:15 am
STL
-
SCL
14h 33m
1 stop
$916Delta
Wed, Jul 15 - Wed, Aug 5
American Airlines Logo
8:30 pm - 10:24 am
SCL
-
STL
14h 54m
1 stop
American Airlines Logo
1:37 pm - 6:50 am
STL
-
SCL
16h 13m
2 stops
$920American Airlines
Thu, Apr 23 - Mon, May 4
LATAM Airlines Logo
8:40 pm - 5:44 pm
SCL
-
STL
22h 04m
1 stop
LATAM Airlines Logo
4:41 pm - 7:15 am
STL
-
SCL
13h 34m
1 stop
$946LATAM Airlines
Mon, Apr 27 - Mon, May 4
American Airlines Logo
8:35 pm - 10:16 am
SCL
-
STL
14h 41m
1 stop
American Airlines Logo
5:24 am - 7:05 am
STL
-
SCL
24h 41m
1 stop
$948American Airlines
Tue, Apr 28 - Tue, May 5
LATAM Airlines Logo
4:50 pm - 10:34 am
SCL
-
STL
18h 44m
2 stops
LATAM Airlines Logo
4:41 pm - 7:15 am
STL
-
SCL
13h 34m
1 stop
$949LATAM Airlines
Thu, Apr 30 - Thu, May 7
American Airlines Logo
8:35 pm - 3:13 pm
SCL
-
STL
19h 38m
2 stops
American Airlines Logo
9:56 am - 7:05 am
STL
-
SCL
20h 09m
2 stops
$950American Airlines
Booking Insights

KAYAK's insights & trends for Santiago to St. Louis flights

Get data-powered insights and trends into flights from Santiago to St. Louis to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santiago to St. Louis?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santiago to St. Louis departing in July.

What is the cheapest month to fly from Santiago to St. Louis?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santiago to St. Louis, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santiago to St. Louis is December, where tickets cost $795 (return) on average. On the other hand, the most expensive months are March and May, where the average cost of round-trip tickets is $1,239 and $1,200 respectively.

Good to know

Low seasonOctober
Cheapest flight$310
Best time to beat the crowds with an average 12% drop in price.
Most popular time to fly with an average 3% increase in price.
Flight from Santiago to St. Louis

When to book flights from Santiago to St. Louis

Are your dates flexible? Find out the best times to travel from Santiago to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santiago to St. Louis

  • What is the cheapest flight from Santiago to St. Louis?

    In the last 3 days, the lowest price for a flight from Santiago to St. Louis was $310 for a one-way ticket and $878 for a round-trip.

  • Do I need a passport to fly between Santiago and St. Louis?

    Yes

  • Which aircraft models fly most regularly from Santiago to St. Louis?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santiago to St. Louis?

    oneworld, and SkyTeam are the airline alliances operating flights between Santiago and St. Louis, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Santiago to St. Louis, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Santiago to St. Louis are Delta and American Airlines. With an average price for the route of $1,159 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $1,150 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Santiago to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Santiago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Santiago with another airline. Booking your flights between Santiago and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Santiago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Santiago to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Santiago to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8288 reviews
8.1Boarding
7.9Comfort
8.5Crew
7.2Food
7.8Entertainment
Airline reviews

Perhaps when you’re sitting in 1st class and the crew closes the bathroom for the pilots, there could be a notification other than holding your hands up as a blockade when you get there and you’re told the restrooms are closed please turn around … especially at night when visibility is poor and you’re met by a flight attendants with their arms up

10.0 ExcellentDebra, Mar 2026
PBI - ATL
Read more Delta reviews

Perhaps when you’re sitting in 1st class and the crew closes the bathroom for the pilots, there could be a notification other than holding your hands up as a blockade when you get there and you’re told the restrooms are closed please turn around … especially at night when visibility is poor and you’re met by a flight attendants with their arms up

First class is comfortable. Enjoyed a movie and was able to relax compared to coach.

Loved flying First Class. Very comfortable. The seat was amazing. Enjoyed a movie and was able to relax so much better than in coach.

No pilots so we were two hours late taking off and then no gate agents when we arrived in Salt Lake.

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

The WiFi was not working. That made for a long flight.

Absolutely no communication on why there's a delay and multiple flight time reschedules. I would have canceled the flight and drove back home if I known it was going to be rescheduled 3 or 4 times.

Another late night flight and MORE men belligerently drinking and yelling. I had to move from first to economy because they were so obnoxious and disruptive. Crazy to go from a cozy chair to cardboard when you were supposed to be in first. Delta allows was too much drinking which leads to belligerent behavior.

I was in first class and literally the men behind me were so aggressively loud I moved myself to economy. This has become so common on Delta - people using audio without headphones, and men on 12am / late night flights drinking and yelling to talk to each other which prevents anyone around them from resting. Pretty crazy to have to move from first to economy (poorer service, less comfort...). Wild wild. Looking into other airlines.

Love delta smaller commuter plane so no entertainment and paid wifi on MKE-LGA leg was extremely unreliable and slow

Delay after delay with little communication then AA lost my luggage and at airport would not assist just said scan this QR code to track your luggage and submit a claim. However QR code provided did not work so have to go back to airport

After changing the departure gate 5 times making us mo e from one side of the airport to the other and then back the flight was delayed nearly 2 hours. The male flight attendant had a bad attitude with the guest being condescending, disrespectful with people who were already on edge.

Easy boarding. Rows are smaller but that may be an older and bigger me now :)

It would have been nice if American tried to care.

American Airlines did everything they could with the high Spring Break crowd. I was frustrated to be changed from 1st class to a middle seat at the back of the plane. This has happened before, not sure booking 1st class and paying the extra actually works.

I booked 1st class, my flights were changed and I was sitting in the middle at the back of the plane. A far cry from the 1st class I purchased for my flights. I am grateful I arrived on time.

Movie selections were very limited. Meals were not f So good.

Older airplane with worn out seats. No entertainment system at all. Connecting to Wi-Fi was problematic and hit and miss.

AA is flying sub par aging 787's to Tokyo. I fly other 787's long haul and these are at the bottom. Seats don't work well, tray tables don't work well and were dirty. The flight was great, the plane was not.

There was no beverage service and the only time I saw a crew member walk through the cabin is when we were preparing to land.

Everything you need to know for your flight from Santiago to St. Louis

Information on your arrival and departure airports