SCL - STL

$756 Find Cheap Flights from Santiago to St. Louis

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to St. Louis departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to St. Louis, as well as popular online travel agencies
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Flight Deals
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Flight Deals

Cheap Flights from Santiago to St. Louis (SCL-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to St. Louis

Mon, Jan 26 - Tue, Feb 3
United Airlines Logo
10:45 pm - 10:00 pmSCL-STL
26h 15m1 stop
United Airlines Logo
10:07 am - 8:50 amSTL-SCL
19h 43m1 stop
$756United Airlines
Find Deal
Thu, Nov 13 - Mon, Nov 17
Delta Logo
11:10 pm - 4:07 pmSCL-STL
19h 57m1 stop
Delta Logo
9:33 am - 6:35 amSTL-SCL
18h 02m2 stops
$764Delta
Find Deal
Sun, Jan 25 - Tue, Feb 3
LATAM Airlines Logo
4:35 am - 11:39 pmSCL-STL
22h 04m2 stops
LATAM Airlines Logo
9:59 am - 11:05 amSTL-SCL
22h 06m3 stops
$924LATAM Airlines
Find Deal
Mon, Dec 15 - Mon, Dec 22
LATAM Airlines Logo
6:40 am - 11:42 pmSCL-STL
20h 02m2 stops
LATAM Airlines Logo
9:47 am - 2:20 pmSTL-SCL
25h 33m2 stops
$971LATAM Airlines
Find Deal
Mon, Dec 15 - Mon, Dec 22
Multiple Airlines Logo
6:40 am - 3:29 pmSCL-STL
35h 49m3 stops
Multiple Airlines Logo
4:05 pm - 4:00 amSTL-SCL
32h 55m3 stops
$1,334Multiple Airlines
Find Deal
Wed, Nov 12 - Mon, Nov 17
Copa Airlines Logo
3:23 am - 7:16 pmSCL-STL
18h 53m2 stops
Copa Airlines Logo
8:25 am - 6:01 amSTL-SCL
18h 36m2 stops
$1,767Copa Airlines
Find Deal
Wed, Nov 12 - Mon, Nov 17
Copa Airlines Logo
1:12 am - 7:16 pmSCL-STL
21h 04m2 stops
Copa Airlines Logo
8:25 am - 6:01 amSTL-SCL
18h 36m2 stops
$1,800Copa Airlines
Find Deal
Sun, Dec 14 - Mon, Dec 22
Air Canada Logo
1:35 am - 10:45 pmSCL-STL
24h 10m3 stops
Air Canada Logo
4:05 pm - 6:50 amSTL-SCL
35h 45m2 stops
$3,122Air Canada
Find Deal
Sun, Dec 14 - Mon, Dec 22
Air Canada Logo
1:35 am - 10:45 pmSCL-STL
24h 10m3 stops
Air Canada Logo
4:05 pm - 6:50 amSTL-SCL
35h 45m3 stops
$3,167Air Canada
Find Deal
Sun, Jan 25 - Tue, Feb 3
Multiple Airlines Logo
4:50 am - 3:29 pmSCL-STL
37h 39m3 stops
Multiple Airlines Logo
4:05 pm - 9:20 pmSTL-SCL
26h 15m3 stops
$8,579Multiple Airlines
Find Deal

Everything you should know

Top airlines
United Airlines
Cheapest • from $756 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Cheapest round-trip
$756
Typical prices: $944-$1,115
United Airlines
Mon 1/26Tue 2/3
SCL - STL • 1 stop
Cheapest one-way
$2,601
LATAM Airlines
Wed 11/12
SCL - STL • 2 stops
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to St. Louis!
Booking Insights

KAYAK's insights & trends for Santiago to St. Louis flights

Get data-powered insights and trends into flights from Santiago to St. Louis to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Santiago to St. Louis?

The average price of all round-trip flights from Santiago to St. Louis clicked on KAYAK for each day over the last 12 months.

When flying from Santiago to St. Louis, you should consider leaving on a Tuesday and avoid Fridays if you are looking for the best rates. For your return to Santiago, you’ll find the best rates on Wednesdays and the most expensive ones on Saturdays.

Good to know

Low seasonAugust
Cheapest flight$756
Best time to beat the crowds with an average 25% drop in price.
Most popular time to fly with an average 3% increase in price.
Flight from Santiago to St. Louis

When to book flights from Santiago to St. Louis

Are your dates flexible? Find out the best times to travel from Santiago to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santiago to St. Louis

  • What is the cheapest flight from Santiago to St. Louis?

    In the last 3 days, the lowest price for a flight from Santiago to St. Louis was $2,601 for a one-way ticket and $756 for a round-trip.

  • Do I need a passport to fly between Santiago and St. Louis?

    Yes

  • Which aircraft models fly most regularly from Santiago to St. Louis?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santiago to St. Louis?

    oneworld, and SkyTeam are the airline alliances operating flights between Santiago and St. Louis, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Santiago to St. Louis, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Santiago to St. Louis are Delta and American Airlines. With an average price for the route of $1,065 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $1,091 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Santiago to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Santiago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Santiago with another airline. Booking your flights between Santiago and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Santiago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Santiago to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Santiago to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7997 reviews
8.2Boarding
7.3Food
7.9Comfort
8.5Crew
7.9Entertainment
Airline reviews

I truly love flying with Delta. They have always treated me with the upmost respect

10.0 ExcellentMAYRA, Nov 2025JFK - MIA
Read more Delta reviews

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

Everything went well and was good. Nothing exceptional, but no complaints either. Cheap seats are pretty comfortable.

DELTA does a terrific job making sure you are well taken care of during the flight, gives you assurance before the flight through numerous email notifications about your upcoming flight & lastly good follow up after the flight making sure your needs were mat. It has been, is & will continue to be my carrier of choice in all my future travels. Good Job DELTA

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

The customer service before board was very rude and when I expressed my concerns about making the connecting flight she laughed and told me I bought the wrong ticket. I explained once it showed the flight was delayed it no longer let me change seats or anything. I was trying to upgrade to make sure I would get to the next gate on time.

Non stop on long haul is the way to go. Great experience

Seats comfortable, service and food very mediocre, staff not very attentive, worse than many other our flights with Delta.

Overall good experience; however, there was one flight attendant who was rather rough compared to everyone else. Everything else was good: entertainment, food. Delta keeps on delivering! Thank you!

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

Wish a flight with more than 2 hours with some snack rather than just cookie/biscuit.

The flight attendant, a black woman with curly hair who sat near Row 21, was wonderful and kind.

It was good..clean, comfy seat. Friendly warm welcoming crew. Was able to check my cabin luggage at the gate which I was able to pickup in a decent time from baggage claim. The app gave all updates from delays to baggage claim info. Overall smooth flight.

Nice comfortable flight from Barcelona back to the states. The premium economy offers the extra room we need for my husband. The food was good and our flight attendants were excellent.

Flight was delayed leaving Dallas. Arrived about 2 hours later than scheduled.

Flight delayed and missed connection. Rescheduled flight cancelled after 6 hrs wait. Rerouted thru ORD, flight cancelled, overnight stay in ORD. Still in the air on new flight!

We are too tired and frustrated to comment politely at this point

Terrible. Our luggage was delayed and couldn’t be delivered for several days. We got bad information from the airline agents at baggage claim. We had to pick up our car so we wouldn’t be charged for an extra day. We got lost in the maze of airport parking. The baggage claim agents didn’t offer us any compensation for our extra time and expense. We are tired, hungry and very frustrated.

The flight was flawless and we even arrived between 20 and 25 minutes early!

Everything you need to know for your flight from Santiago to St. Louis

Information on your arrival and departure airports

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