SCL - STL

$617 Find Cheap Flights from Santiago to St. Louis

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to St. Louis departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to St. Louis, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 22% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flights Deals
Booking Insights
Flights Deals

Cheap Flights from Santiago to St. Louis (SCL-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to St. Louis

Wed, Sep 17 - Wed, Sep 24
Delta Logo
9:40 pm - 9:15 pmSCL-STL
25h 35m1 stop
Delta Logo
7:10 am - 7:00 amSTL-SCL
21h 50m1 stop
$775Delta
Find Deal
Sun, Sep 14 - Mon, Sep 22
LATAM Airlines Logo
12:25 am - 9:15 pmSCL-STL
22h 50m2 stops
LATAM Airlines Logo
6:42 pm - 5:35 pmSTL-SCL
20h 53m2 stops
$779LATAM Airlines
Find Deal
Thu, Nov 13 - Mon, Nov 17
Delta Logo
11:40 pm - 4:40 pmSCL-STL
20h 00m1 stop
Delta Logo
11:51 am - 7:00 amSTL-SCL
16h 09m1 stop
$784Delta
Find Deal
Wed, Nov 12 - Mon, Nov 17
Delta Logo
12:55 am - 6:02 pmSCL-STL
20h 07m2 stops
Delta Logo
1:30 pm - 7:00 amSTL-SCL
14h 30m2 stops
$788Delta
Find Deal
Mon, Sep 15 - Mon, Sep 22
LATAM Airlines Logo
9:40 pm - 9:59 amSCL-STL
14h 19m1 stop
LATAM Airlines Logo
6:42 pm - 7:00 amSTL-SCL
34h 18m1 stop
$790LATAM Airlines
Find Deal
Fri, Dec 5 - Mon, Dec 8
United Airlines Logo
10:45 pm - 12:15 pmSCL-STL
16h 30m2 stops
United Airlines Logo
6:15 am - 8:50 amSTL-SCL
23h 35m1 stop
$810United Airlines
Find Deal
Thu, Dec 4 - Mon, Dec 8
LATAM Airlines Logo
4:35 am - 11:39 pmSCL-STL
22h 04m2 stops
LATAM Airlines Logo
9:00 am - 6:25 amSTL-SCL
18h 25m2 stops
$824LATAM Airlines
Find Deal
Fri, Dec 5 - Mon, Dec 8
LATAM Airlines Logo
7:15 am - 11:39 pmSCL-STL
19h 24m3 stops
LATAM Airlines Logo
1:30 pm - 2:30 pmSTL-SCL
22h 00m3 stops
$828LATAM Airlines
Find Deal
Tue, Sep 16 - Wed, Sep 24
LATAM Airlines Logo
12:25 am - 7:05 pmSCL-STL
20h 40m2 stops
LATAM Airlines Logo
5:11 pm - 1:20 pmSTL-SCL
18h 09m2 stops
$840LATAM Airlines
Find Deal
Sun, Sep 14 - Mon, Sep 22
LATAM Airlines Logo
12:25 am - 9:15 pmSCL-STL
22h 50m2 stops
LATAM Airlines Logo
3:36 pm - 7:00 amSTL-SCL
13h 24m1 stop
$975LATAM Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Santiago to St. Louis flights

Get data-powered insights and trends into flights from Santiago to St. Louis to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santiago to St. Louis?

What’s the cheapest day of the week to fly from Santiago to St. Louis?

The average price of all round-trip flights from Santiago to St. Louis clicked on KAYAK for each day over the last 12 months.

When flying from Santiago to St. Louis, you should consider leaving on a Tuesday and avoid Fridays if you are looking for the best rates. For your return to Santiago, you’ll find the best rates on Wednesdays and the most expensive ones on Saturdays.

Good to know

Low seasonNovember
Cheapest flight$617
Best time to beat the crowds with an average 23% drop in price.
Most popular time to fly with an average 1% increase in price.
Flight from Santiago to St. Louis

When to book flights from Santiago to St. Louis

Are your dates flexible? Find out the best times to travel from Santiago to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santiago to St. Louis

  • What is the cheapest flight from Santiago to St. Louis?

    In the last 3 days, the lowest price for a flight from Santiago to St. Louis was $617 for a one-way ticket and $775 for a round-trip.

  • Do I need a passport to fly between Santiago and St. Louis?

    Yes

  • Which aircraft models fly most regularly from Santiago to St. Louis?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santiago to St. Louis?

    SkyTeam, and Star Alliance are the airline alliances operating flights between Santiago and St. Louis, with SkyTeam being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from Santiago to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Santiago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Santiago with another airline. Booking your flights between Santiago and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Santiago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Santiago to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Santiago to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7986 reviews
8.2Boarding
7.9Comfort
8.5Crew
7.9Entertainment
7.3Food
Airline reviews

My experience on any Delta flight is always overshadowed by the time Delta removed me from a flight for no apparent reason.

2.0 MediocreGim, Jul 2025BGM - DTW
Read more Delta reviews

My experience on any Delta flight is always overshadowed by the time Delta removed me from a flight for no apparent reason.

Check in process was terrible. Lady at counter didn’t know what she was doing

Delayed and took off even later than the scheduled delay time

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Great experience on Delta. Staff from baggage check to flight attendants were very courteous and professional. My only issue was a personal preference for pretzels instead of the chips and cookies that were offered.

The crew was amazing; Von, Vera and Guadalupe were very friendly and attentive throughout the entire flight. They were friendly and welcoming to everyone. A solid and dedicated team for sure!

Terrible. I was bumped off of my original flight and spent the next six days fighting to get back on it. I lost hours of my vacation trying to get this situation corrected.

There was no problems, just a little uncomfortable with seats that do not lay back a little

Always good but we must do something about people in rows ahead of you that don't put their seats back up when they are suppose to. And It's rough to not be able to even lean over to get something out of my purse.

Flight was delayed, 30+ bags had to be gate checked. Crew were very friendly!

Pathetic check in experience once again. Not enough staff scheduled at bag drop or for special assistance at LHR. Really need to rethink the whole self check in procedure. The crew was good. A very decent selection of special meals in this leg as compared to the JFK-LHR leg.

We had to turn around and head back to Manchester. Problem with a plane engine.

Flight was delayed. Staff at the gate effectively and proactively communicated about the delay.

Very poor delay in dfw was really bad n long

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

Because of rescheduling, they had to put me on a flight that didn't go through Dallas

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

3 hour weather delay followed by 1 hour (and counting) maintenance delay. UGH!

Couldn’t get the door on the plane to close leading to a nearly 2 hour delay. But, hey at least they didn’t cancel the flight.

Very clean and comfortable cabin. Amazing Mediterranean salad for lunch before landing. Great range of films to watch. Really quiet and easy to sleep on the flight also. The initial food was a bit weird: odd fried chicken pieces in some weird white gloop, but that would be my lack of cultural knowledge on the grub. Salad more than made up for it at the other end. Staff were super attentive and helpful. Great and easy flight

Everything you need to know for your flight from Santiago to St. Louis

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.