SCL - PTY

$291 Find Cheap Flights from Santiago to Panama City - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to Panama City departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$610
Typical prices: $569-$708
Avianca
Tue 7/21Wed 7/29
SCL - PTY • 1 stop
Cheapest non-stop
$620
Typical prices: $472-$632
Copa Airlines
Tue 10/20Sat 10/31
SCL - PTY • Non-stop
Top airlines
Cheapest • from $610 (round-trip)
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
You can fly direct with Copa Airlines. Average duration is 6h 53m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Avoid delays
Most punctual • 97% on-time
Best time • Fewest delays
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 2 weeks in advance save around 26% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 16% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santiago to Panama City (SCL-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to Panama City

Tue, Jul 21 - Wed, Jul 29
Avianca Logo
6:40 am - 2:15 pm
SCL
-
PTY
8h 35m
1 stop
Avianca Logo
5:55 pm - 4:45 am
PTY
-
SCL
9h 50m
1 stop
$610Avianca
Sun, Sep 20 - Sat, Sep 26
Avianca Logo
7:40 am - 12:35 am
SCL
-
PTY
18h 55m
1 stop
Avianca Logo
4:25 am - 3:15 pm
PTY
-
SCL
8h 50m
1 stop
$612Avianca
Mon, Oct 12 - Sun, Oct 25
Copa Airlines Logo
5:15 am - 10:03 am
SCL
-
PTY
6h 48mnonstop
Copa Airlines Logo
3:08 pm - 11:39 pm
PTY
-
SCL
6h 31mnonstop
$620Copa Airlines
Thu, Oct 1 - Thu, Oct 15
Avianca Logo
7:40 am - 2:15 pm
SCL
-
PTY
8h 35m
1 stop
Avianca Logo
10:10 am - 12:20 am
PTY
-
SCL
12h 10m
1 stop
$622Avianca
Thu, Oct 1 - Thu, Oct 15
Avianca Logo
7:40 am - 2:15 pm
SCL
-
PTY
8h 35m
1 stop
Avianca Logo
10:10 am - 12:20 am
PTY
-
SCL
12h 10m
1 stop
$624Avianca
Sat, Dec 12 - Tue, Jan 19
Copa Airlines Logo
5:07 am - 10:03 am
SCL
-
PTY
6h 56mnonstop
Copa Airlines Logo
3:08 pm - 11:40 pm
PTY
-
SCL
6h 32mnonstop
$635Copa Airlines
Tue, Jul 14 - Tue, Jul 21
Avianca Logo
3:20 pm - 12:35 am
SCL
-
PTY
10h 15m
1 stop
Avianca Logo
5:55 pm - 2:15 pm
PTY
-
SCL
19h 20m
1 stop
$642Avianca
Sat, Jul 18 - Fri, Jul 24
Avianca Logo
3:20 pm - 2:15 pm
SCL
-
PTY
23h 55m
1 stop
Avianca Logo
4:25 am - 2:15 pm
PTY
-
SCL
8h 50m
1 stop
$643Avianca
Mon, Jul 13 - Tue, Jul 21
Copa Airlines Logo
2:14 am - 8:03 am
SCL
-
PTY
6h 49mnonstop
Copa Airlines Logo
12:01 pm - 7:36 pm
PTY
-
SCL
6h 35mnonstop
$644Copa Airlines
Tue, Sep 15 - Tue, Sep 22
Copa Airlines Logo
3:14 am - 8:03 am
SCL
-
PTY
6h 49mnonstop
Copa Airlines Logo
12:01 pm - 8:32 pm
PTY
-
SCL
6h 31mnonstop
$650Copa Airlines
Booking Insights

KAYAK's insights & trends for Santiago to Panama City flights

Get data-powered insights and trends into flights from Santiago to Panama City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santiago to Panama City?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santiago to Panama City departing in July.

What’s the cheapest day of the week to fly from Santiago to Panama City?

The average price of all round-trip flights from Santiago to Panama City clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Panama City on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Sunday is the most expensive day to fly from Santiago to Panama City. For your return ticket, we recommend flying on a Thursday and avoiding Saturdays for the best deals.

What is the cheapest month to fly from Santiago to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santiago to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santiago to Panama City is November, where tickets cost $472 (return) on average. On the other hand, the most expensive months are September and July, where the average cost of round-trip tickets is $677 and $617 respectively.

Can I save money by flying with a layover from Santiago to Panama City?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $602, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Santiago to Panama City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santiago to Panama City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santiago to Panama City, you should book around 2 weeks before departure, which saves you about 26% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 13 weeks before departure.

Good to know

Low seasonAugust
Cheapest flight$291
Best time to beat the crowds but there is an average 3% increase in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Santiago to Panama City

When to book flights from Santiago to Panama City

Are your dates flexible? Find out the best times to travel from Santiago to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santiago to Panama City

  • What is the cheapest flight from Santiago to Panama City?

    In the last 5 days, the lowest price for a flight from Santiago to Panama City was $291 for a one-way ticket and $610 for a round-trip.

  • Do I need a passport to fly between Santiago and Panama City?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Santiago and on arrival in Panama City.

  • Which airlines offer Wi-Fi service onboard planes from Santiago to Panama City?

    Only American Airlines offers inflight Wi-Fi service on the Santiago to Panama City flight route.

  • Which aircraft models fly most regularly from Santiago to Panama City?

    The Boeing 787-8 Dreamliner is the aircraft model that flies most regularly on the Santiago to Panama City flight route.

  • Which airline alliances offer flights from Santiago to Panama City?

    Star Alliance is the only airline alliance operating flights between Santiago and Panama City.

  • On which days can I fly direct from Santiago to Panama City?

    There are nonstop flights from Santiago to Panama City on a daily basis.

  • How does KAYAK find such low prices on flights from Santiago to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Santiago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Santiago with another airline. Booking your flights between Santiago and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Santiago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Santiago to Panama City

  • Looking for a cheap flight? 25% of our users found flights on this route for $348 or less one-way and $471 or less round-trip.

Prefer to fly direct from Santiago to Panama City?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Santiago Arturo Merino Benitez to Panama City Tocumen Intl.
Find which airlines fly direct from Santiago Arturo Merino Benitez Airport to Panama City Tocumen Intl Airport, which days they fly and book direct flights.

Direct departures

Santiago Arturo Merino Benitez to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

Panama City Tocumen Intl to Santiago Arturo Merino Benitez

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top airline flying from Santiago to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Santiago to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1569 reviews
6.9Food
8.1Crew
7.8Boarding
7.4Comfort
6.8Entertainment
Airline reviews

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

6.0 GoodAnonymous, May 2026
SCL - PTY
Read more Copa Airlines reviews

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

I was flying business class, and the French fellow passengers were super noisy. It was not a comfortable flight. And the crew was not helpful.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Entire experience from check in to landing was amazing the flight crew was excellent and friendly. Seats were comfortable.

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

Seats were awful. Media should have been included for such a long flight.

Everything you need to know for your flight from Santiago to Panama City

Information on your arrival and departure airports