SCL - PTY

$245 Find Cheap Flights from Santiago to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to Panama City departing on 3/30. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Panama City, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$540
Typical prices: $486-$609
Avianca
Thu 3/5Mon 3/23
SCL - PTY • 1 stop
Cheapest non-stop
$570
Typical prices: $546-$689
Copa Airlines
Sat 7/4Mon 7/13
SCL - PTY • Non-stop
Top airlines
Avianca
Cheapest • from $540 (round-trip)
Copa Airlines
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
6 weeks
in advance
Our data shows that travelers who book at least 6 weeks in advance save around 21% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
November
Cheapest • 10% price drop
February
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santiago to Panama City (SCL-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to Panama City

Thu, Mar 5 - Mon, Mar 23
Avianca Logo
1:35 am - 8:50 am
SCL
-
PTY
9h 15m
1 stop
Avianca Logo
2:55 pm - 5:30 am
PTY
-
SCL
12h 35m
1 stop
$540Avianca
Sun, Jul 19 - Thu, Jul 30
Avianca Logo
11:55 pm - 9:10 pm
SCL
-
PTY
22h 15m
1 stop
Avianca Logo
3:20 am - 10:30 pm
PTY
-
SCL
18h 10m
1 stop
$550Avianca
Wed, May 20 - Sun, May 31
Avianca Logo
6:10 am - 9:10 pm
SCL
-
PTY
16h 00m
1 stop
Avianca Logo
10:05 pm - 1:25 pm
PTY
-
SCL
14h 20m
1 stop
$560Avianca
Mon, May 4 - Mon, May 11
Avianca Logo
11:55 pm - 9:10 pm
SCL
-
PTY
22h 15m
1 stop
Avianca Logo
11:05 am - 10:30 pm
PTY
-
SCL
10h 25m
1 stop
$561Avianca
Sat, Jul 4 - Sun, Jul 26
Copa Airlines Logo
2:27 am - 8:16 am
SCL
-
PTY
6h 49mnonstop
Copa Airlines Logo
7:25 pm - 3:00 am
PTY
-
SCL
6h 35mnonstop
$570Copa Airlines
Thu, Feb 19 - Tue, May 19
Avianca Logo
1:35 am - 2:00 pm
SCL
-
PTY
14h 25m
1 stop
Avianca Logo
10:05 pm - 1:25 pm
PTY
-
SCL
14h 20m
1 stop
$578Avianca
Thu, Apr 9 - Sun, Apr 19
Copa Airlines Logo
11:25 am - 5:11 pm
SCL
-
PTY
6h 46mnonstop
Copa Airlines Logo
7:25 pm - 3:00 am
PTY
-
SCL
6h 35mnonstop
$585Copa Airlines
Sat, Jun 20 - Fri, Jul 3
Copa Airlines Logo
11:17 am - 5:11 pm
SCL
-
PTY
6h 54mnonstop
Copa Airlines Logo
9:28 pm - 5:03 am
PTY
-
SCL
6h 35mnonstop
$600Copa Airlines
Thu, Feb 12 - Fri, Mar 13
Copa Airlines Logo
1:46 am - 6:22 am
SCL
-
PTY
6h 36mnonstop
Copa Airlines Logo
11:48 am - 8:20 pm
PTY
-
SCL
6h 32mnonstop
$610Copa Airlines
Wed, Feb 4 - Sun, Feb 8
Avianca Logo
1:35 am - 4:55 pm
SCL
-
PTY
17h 20m
1 stop
Avianca Logo
9:45 am - 5:30 am
PTY
-
SCL
17h 45m
1 stop
$630Avianca
Booking Insights

KAYAK's insights & trends for Santiago to Panama City flights

Get data-powered insights and trends into flights from Santiago to Panama City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santiago to Panama City?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santiago to Panama City departing in March.

What’s the cheapest day of the week to fly from Santiago to Panama City?

The average price of all round-trip flights from Santiago to Panama City clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Panama City on a Friday, as we generally find the cheapest rates on that day for this route. On the other hand, Monday is the most expensive day to fly from Santiago to Panama City. For your return ticket, we recommend flying on a Monday and avoiding Fridays for the best deals.

What is the cheapest month to fly from Santiago to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santiago to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santiago to Panama City is November, where tickets cost $495 (return) on average. On the other hand, the most expensive months are September and July, where the average cost of round-trip tickets is $660 and $584 respectively.

Can I save money by flying with a layover from Santiago to Panama City?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $462 on average.

How far in advance should I book a flight from Santiago to Panama City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santiago to Panama City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santiago to Panama City, you should book around 6 weeks before departure, which saves you about 21% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 17 weeks before departure.

Good to know

Low seasonAugust
Cheapest flight$245
Best time to beat the crowds with an average 2% drop in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Santiago to Panama City

When to book flights from Santiago to Panama City

Are your dates flexible? Find out the best times to travel from Santiago to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santiago to Panama City

  • What is the cheapest flight from Santiago to Panama City?

    In the last 3 days, the lowest price for a flight from Santiago to Panama City was $245 for a one-way ticket and $540 for a round-trip.

  • Do I need a passport to fly between Santiago and Panama City?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Santiago and on arrival in Panama City.

  • Which airlines offer Wi-Fi service onboard planes from Santiago to Panama City?

    American Airlines, Air Canada, and Delta offer inflight Wi-Fi service on the Santiago to Panama City flight route.

  • Which aircraft models fly most regularly from Santiago to Panama City?

    The Boeing 737 MAX 9 is the aircraft model that flies most regularly on the Santiago to Panama City flight route.

  • Which airline alliances offer flights from Santiago to Panama City?

    Star Alliance is the only airline alliance operating flights between Santiago and Panama City.

  • On which days can I fly direct from Santiago to Panama City?

    There are nonstop flights from Santiago to Panama City on a daily basis.

  • Which is the best airline for flights from Santiago to Panama City, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Santiago to Panama City are Copa Airlines and Avianca. With an average price for the route of $598 and an overall rating of 7.6, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $568 and an overall rating of 6.6.

  • How does KAYAK find such low prices on flights from Santiago to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Santiago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Santiago with another airline. Booking your flights between Santiago and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Santiago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Santiago to Panama City

  • Looking for a cheap flight? 25% of our users found flights on this route for $329 or less one-way and $501 or less round-trip.

Prefer to fly direct from Santiago to Panama City?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Santiago Arturo Merino Benitez to Panama City Tocumen Intl.
Find which airlines fly direct from Santiago Arturo Merino Benitez Airport to Panama City Tocumen Intl Airport, which days they fly and book direct flights.

Direct departures

Santiago Arturo Merino Benitez to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

Panama City Tocumen Intl to Santiago Arturo Merino Benitez

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top airlines flying from Santiago to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Santiago to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1557 reviews
6.8Entertainment
8.1Crew
6.8Food
7.4Comfort
7.8Boarding
Airline reviews

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

2.0 MediocreAnonymous, Dec 2025
LAS - PTY
Read more Copa Airlines reviews

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

only a bag of chips and a bottle of water in business class was served

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

I had to go to the boarding counter for them to enter my return flight as it’s not with Avianca. There was a long queue as there were lots of people being called to the counter.

Did not fly with Pakistan International Airlines. Have never flown with Pakistan International Airlines.

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

Luggage lost and nowhere to be found, no response from either airline regarding my bag

The usb plugs for charging your phone didn’t work, the seats were coarse and hard. Not very comfortable. No inflight WiFi

Everything you need to know for your flight from Santiago to Panama City

Information on your arrival and departure airports