$279 Find Cheap Flights from Santiago to Panama City - Compare and Save

These are the earliest and latest flight times available from Santiago to Panama City:

• Earliest: departs at 1:02 am and lands at 7:55 am
• Latest: departs at 12:23 pm and lands at 7:16 pm.

The flight takes about 6h 53m.

Two cabin classes are available on flights from Santiago to Panama City:

• Economy Class
• Business Class

A nonstop flight from Santiago to Panama City takes 6h 53m, covering 2,986 miles.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Round-trip flights from Santiago to Panama City range from $521 to $662, with an average of $574 over the past 12 months. Anything below $521 counts as a good deal.

Last-minute fares on this route (booked within two weeks of departure) run 26% above the $574 route average. Book 17 weeks before departure for the lowest fares.

On this route, nonstop flights are cheaper than layover options on average. Nonstop fares average $566 round-trip, compared to $601 via a layover through Bogotá El Dorado (BOG).

Copa Airlines is the only airline operating Santiago to Panama City flights. 96% of its flights are on time.

There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $100–$100 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

The Boeing 787-8 Dreamliner family is used most often on this route, operated mainly by LATAM Airlines and Delta. Other aircraft seen on the route include Boeing 737 MAX 9 variants.

Night is the busiest departure period on Santiago to Panama City flights, with 66% of flights leaving in that window. Morning departures account for 17%, afternoon flights for 17%, and evening flights for 0%.

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $562 to $3,175. That means the highest observed fare was about 6x higher than the lowest one.

One-way fares from Santiago to Panama City are currently higher than usual. Average one-way flight prices are about $339, which is 15% above the typical average for this route.

Panama City Tocumen Intl Airport (PTY) hosts 5 major car rental companies, with daily rates starting from around $1 for economy cars. Top options include:

• Avis
• Europcar
• Ace
• Budget
• Hertz

Flights from Santiago to Panama City usually depart from Santiago Arturo Merino Benitez (SCL) and arrive at Panama City Tocumen Intl (PTY).

Afternoon flights have the fewest delays on this route, while night departures tend to have the most.

A flight is considered delayed when it departs 15 minutes or more after its scheduled time. This is the standard used by the US Department of Transportation and most airline industry reporting. On the Santiago to Panama City route, 4% of flights were delayed in the past 3 months, with delays averaging 2h 03m.

Most connecting flights from Santiago to Panama City pass through Bogotá El Dorado (BOG), which handles 100% of one-stop traffic on this route.

Yes. Flexible dates can save you up to 8% on flights from Santiago to Panama City. Thursday is the cheapest departure day at $553 round-trip on average, while Sunday is the most expensive at $596, a difference of $43.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Only Copa Airlines operates flights between Santiago and Panama City.

Panama City is 2 hours behind Santiago (Eastern Time vs Chile Time). Plan for the time shift when scheduling connections or first-day activities.

Some of the most popular sights in Panama City are ATLAPA Conventions Center, Panama Old Cathedral and Veneto Casino. These are among the most viewed places in Panama City on KAYAK.

Among airlines operating Santiago to Panama City flights:

• Copa Airlines: offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Here are some options for this route, based on selected ticket types and cabin classes:

• Copa Airlines: a cabin bag and a checked bag in Economy Class

Bag allowance can vary by ticket type, cabin class, route and airline, so always check the fare details before booking.