PTY - SCL

$286 Find Cheap Flights from Panama City to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Santiago departing on 6/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Santiago, as well as popular online travel agencies
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Flights Deals

Cheap Flights from Panama City to Santiago (PTY-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Santiago

Sun, Jun 22 - Mon, Jun 30
Avianca Logo
3:20 am - 1:25 pmPTY-SCL
9h 05m1 stop
Avianca Logo
6:10 am - 9:10 pmSCL-PTY
16h 00m1 stop
$514Avianca
Find Deal
Mon, Jun 9 - Sat, Jun 14
Avianca Logo
3:25 am - 1:25 pmPTY-SCL
9h 00m1 stop
Avianca Logo
2:30 pm - 12:10 amSCL-PTY
10h 40m1 stop
$540Avianca
Find Deal
Fri, Jul 4 - Sat, Jul 12
Avianca Logo
3:25 am - 1:25 pmPTY-SCL
9h 00m1 stop
Avianca Logo
2:30 pm - 12:10 amSCL-PTY
10h 40m1 stop
$542Avianca
Find Deal
Wed, Jul 30 - Sun, Aug 17
Avianca Logo
3:20 am - 10:30 pmPTY-SCL
18h 10m1 stop
Avianca Logo
2:30 pm - 12:10 amSCL-PTY
10h 40m1 stop
$544Avianca
Find Deal
Mon, Jun 2 - Sun, Jun 8
Copa Airlines Logo
9:28 pm - 5:04 amPTY-SCL
6h 36mnonstop
Copa Airlines Logo
12:13 am - 6:05 amSCL-PTY
6h 52mnonstop
$594Copa Airlines
Find Deal
Fri, Oct 31 - Sat, Nov 8
Copa Airlines Logo
3:21 pm - 11:54 pmPTY-SCL
6h 33mnonstop
Copa Airlines Logo
4:19 am - 9:12 amSCL-PTY
6h 53mnonstop
$604Copa Airlines
Find Deal
Sat, Jul 5 - Sat, Jul 12
 Logo
9:55 am - 9:15 pmPTY-SCL
34h 20m2 stops
 Logo
2:30 pm - 12:10 amSCL-PTY
10h 40m1 stop
Fri, Jul 4 - Sat, Jul 12
 Logo
3:25 am - 1:25 pmPTY-SCL
9h 00m1 stop
 Logo
6:01 am - 9:10 pmSCL-PTY
16h 09m3 stops
Mon, Nov 10 - Sun, Nov 16
United Airlines Logo
4:00 pm - 8:50 amPTY-SCL
38h 50m2 stops
United Airlines Logo
10:45 pm - 8:02 pmSCL-PTY
47h 17m3 stops
$1,275United Airlines
Find Deal
Fri, Oct 31 - Fri, Nov 7
United Airlines Logo
3:00 pm - 7:50 amPTY-SCL
38h 50m2 stops
United Airlines Logo
10:45 pm - 8:02 pmSCL-PTY
23h 17m2 stops
$1,307United Airlines
Find Deal
Useful Info

KAYAK's insights & trends for Panama City to Santiago flights

Get data-powered insights and trends into flights from Panama City to Santiago to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Panama City to Santiago?

The average price of all round-trip flights from Panama City to Santiago clicked on KAYAK for each day over the last 12 months.

When flying from Panama City to Santiago, you should consider leaving on a Thursday and avoid Wednesdays if you are looking for the best rates. For your return to Panama City, you’ll find the best rates on Sundays and the most expensive ones on Mondays.

What is the cheapest month to fly from Panama City to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Santiago is August, where tickets cost $473 (return) on average. On the other hand, the most expensive months are January and February, where the average cost of round-trip tickets is $632 and $588 respectively.

Can I save money by flying with a layover from Panama City to Santiago?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $578, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Panama City to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Santiago, you should book around 8 weeks before departure. For the absolute cheapest price, our data suggests you should book 19 weeks before departure.

Good to know

Low seasonApril
High seasonOctober
Cheapest flight$286
Best time to beat the crowds but there is an average 3% increase in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Panama City to Santiago

When to book flights from Panama City to Santiago

Are your dates flexible? Find out the best times to travel from Panama City to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Santiago

  • What is the cheapest flight from Panama City to Santiago?

    In the last 3 days, the lowest price for a flight from Panama City to Santiago was $286 for a one-way ticket and $514 for a round-trip.

  • Do I need a passport to fly between Panama City and Santiago?

    Yes

  • Which aircraft models fly most regularly from Panama City to Santiago?

    The Boeing 737-800 is the aircraft model that flies most regularly on the Panama City to Santiago flight route.

  • Which airline alliances offer flights from Panama City to Santiago?

    Star Alliance, and SkyTeam are the airline alliances operating flights between Panama City and Santiago, with Star Alliance being the most commonly used for this route.

  • On which days can I fly direct from Panama City to Santiago?

    There are nonstop flights from Panama City to Santiago on a daily basis.

  • Which is the best airline for flights from Panama City to Santiago, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Panama City to Santiago are Copa Airlines and Avianca. With an average price for the route of $603 and an overall rating of 7.5, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $421 and an overall rating of 6.7.

  • How does KAYAK find such low prices on flights from Panama City to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Panama City with another airline. Booking your flights between Panama City and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Santiago

  • Looking for a cheap flight? 25% of our users found flights on this route for $573 or less round-trip.

Prefer to fly direct from Panama City to Santiago?

Find which airlines fly direct from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Santiago Arturo Merino Benitez

Monday

Copa Airlines, KLM, Turkish Airlines

Copa Airlines, KLM, +1 more

Tuesday

Copa Airlines, KLM, Turkish Airlines

Copa Airlines, KLM, +1 more

Wednesday

Copa Airlines, KLM, Turkish Airlines

Copa Airlines, KLM, +1 more

Thursday

Copa Airlines, KLM, Turkish Airlines

Copa Airlines, KLM, +1 more

Friday

Copa Airlines, KLM, Turkish Airlines

Copa Airlines, KLM, +1 more

Saturday

Copa Airlines, KLM, Turkish Airlines

Copa Airlines, KLM, +1 more

Sunday

Copa Airlines, KLM, Turkish Airlines

Copa Airlines, KLM, +1 more

See more direct flights

Direct returns

Santiago Arturo Merino Benitez to Panama City Tocumen Intl

Monday

Copa Airlines, KLM, Turkish Airlines

Copa Airlines, KLM, +1 more

Tuesday

Copa Airlines, KLM, Turkish Airlines

Copa Airlines, KLM, +1 more

Wednesday

Copa Airlines, KLM, Turkish Airlines

Copa Airlines, KLM, +1 more

Thursday

Copa Airlines, KLM, Turkish Airlines

Copa Airlines, KLM, +1 more

Friday

Copa Airlines, KLM, Turkish Airlines

Copa Airlines, KLM, +1 more

Saturday

Copa Airlines, KLM, Turkish Airlines

Copa Airlines, KLM, +1 more

Sunday

Copa Airlines, KLM, Turkish Airlines

Copa Airlines, KLM, +1 more

See more direct flights
See more direct flights

Top airlines flying from Panama City to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1428 reviews
7.4Comfort
6.8Entertainment
8.1Crew
7.8Boarding
6.8Food
Airline reviews

The flight was delayed twice and I could not speak with anyone at the airport about checking in. The phone number to Copa - the customer service agents were polite. They are just limited at helping because they are not at the airport

2.0 MediocreAnonymous, May 2025PTY - MDE
Read more Copa Airlines reviews

The flight was delayed twice and I could not speak with anyone at the airport about checking in. The phone number to Copa - the customer service agents were polite. They are just limited at helping because they are not at the airport

We were in transit from Lima (flight at 1.10am) and we were in stand by in our flight from Panama to Washington. We wait from 4.30 am to 18.30pm in the Airport. The company give us 2 x 15 dollars for eat during the day and a personnal travel voucher of 400 dollars each. Do they buy food one time something in the Airport ??? And one of us live in France so the voucher is not usable. More than 24 hours travel !! And our place were near the toilets, with 8 children around us. The boy behind my seat stamped his feet on my back all the flight. Really Wonder full ! So we are totally unhappy with our travel. Thanks Copa Airlines....

I upgraded myself to Business Class at the last minute so I had a DREAMS window seat. Seeing as I've never flown Business before everything was novel and fun for me and it made the 7 hour flight much more enjoyable for sure.

No headphones given for inflight entertainment. I missed my flight from the previous day and the customer service agent tried to extort an additional $100.00 US from me for missing my flight. Really?!

The flight was delayed about 4 hours without any explanation. No wifi or entertainment at all on planes. Had to pay for checked bags I was allowed according to reservations.

It was good, plane is a bit older so seats are somewhat flat

Friendly flight team and seamless travel from one stop to next.

I loved my experience. Very safe, Very informative and very friendly.

Check in person said there would be lunch. We were first class passengers and lunch was chips.

Flight attendant -José? - was over the top friendly and professional. Beautiful new plane with lie flat seats in Business (worth it!)

A few years ago long flights 6 hours or so used to have video screens and they offered ear phones. The food cart used to come and drinks. Now absolutely nothing. Avianca is as bad as Spirit Airlines. Avianca will now be my last choice when booking my next flight.

Purchased a business class ticket and got a economy seat with center seat blocked they call it business. 3100usd ticket on a flight where economy costs 500usd The biggest scam insult have had on a regular airline. Avianca should be in the low cost category and kicked out of Star Alliance. I want the difference to be credited. Ets see what Avianca does. No reply so far. Avianca = low cost airline. Beware

Business class seats did not lie flat. There was only powdered milk for your coffee....in Business Class!! Food was good.

The seats were very uncomfortable. I would have upgrade or got different flight if I knew. I usually sleep in the plane but I couldn’t sleep at all. Very uncomfortable. Also no food or drink everything was to purchase, and that’s u usual for international flight.

We did not know about the bag fees until check in. They are way too high. It’s insane. We also had a huge delay and everything costed extra which was very annoying.

We were not aware carry-on bags cost extra until we arrived at the airport so, we were charged $240.00 for two small carry- on bags! There was a substantial fee for drinks and snacks. No wifi, or other entertainment was available. Waiting areas were crowded and uncomfortable.

COP 7,000 for a cup of mediocre coffee. I thought I was on Spirit Airlines for a minute. Otherwise the flight was fine. Nothing exceptional to report.

please see previous response; it covers the whole travel trajectory.

Worst airline , charge for everything even for water, seat space is very bad

Horrible. I have been trying to speak to a representative to know why I was over charged but I get redirected to AI Vianca everytime with no results. Is there an agency that oversees airline gouging? I will never fly or recommend Avianca to anyone not that you care.

Everything you need to know for your flight from Panama City to Santiago

Information on your arrival and departure airports

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