PTY - SCL

$289 Find Cheap Flights from Panama City to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Santiago departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Santiago, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$553
Typical prices: $657-$514
Avianca
Thu 5/21Wed 5/27
PTY - SCL • 1 stop
Cheapest non-stop
$590
Typical prices: $700-$561
Copa Airlines
Fri 5/15Fri 5/22
PTY - SCL • Non-stop
Top airlines
Cheapest • from $553 (round-trip)
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
You can fly direct with Copa Airlines. Average duration is 6h 35m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Avoid delays
Most punctual • 95% on-time
Best time • Fewest delays
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 8% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 3% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Santiago (PTY-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Santiago

Thu, May 21 - Wed, May 27
Avianca Logo
10:10 am - 11:20 pm
PTY
-
SCL
12h 10m
1 stop
Avianca Logo
12:30 am - 2:15 pm
SCL
-
PTY
14h 45m
1 stop
$553Avianca
Thu, Jun 18 - Sun, Jun 21
Avianca Logo
10:10 am - 4:45 am
PTY
-
SCL
17h 35m
1 stop
Avianca Logo
3:20 pm - 12:35 am
SCL
-
PTY
10h 15m
1 stop
$568Avianca
Thu, Apr 30 - Sun, May 3
Avianca Logo
4:25 am - 2:15 pm
PTY
-
SCL
8h 50m
1 stop
Avianca Logo
3:20 pm - 12:35 am
SCL
-
PTY
10h 15m
1 stop
$569Avianca
Tue, May 26 - Tue, Jun 2
Avianca Logo
4:25 am - 11:20 pm
PTY
-
SCL
17h 55m
1 stop
Avianca Logo
12:30 am - 9:15 am
SCL
-
PTY
9h 45m
1 stop
$571Avianca
Thu, Apr 30 - Sun, May 3
Avianca Logo
3:10 pm - 4:45 am
PTY
-
SCL
12h 35m
1 stop
Avianca Logo
6:40 am - 2:15 pm
SCL
-
PTY
8h 35m
1 stop
$576Avianca
Thu, Apr 30 - Wed, May 6
Avianca Logo
10:10 am - 4:45 am
PTY
-
SCL
17h 35m
1 stop
Avianca Logo
12:30 am - 9:15 am
SCL
-
PTY
9h 45m
1 stop
$578Avianca
Wed, May 6 - Tue, May 19
Avianca Logo
5:55 pm - 4:45 am
PTY
-
SCL
9h 50m
1 stop
Avianca Logo
3:20 pm - 12:35 am
SCL
-
PTY
10h 15m
1 stop
$580Avianca
Sun, Apr 26 - Sun, May 3
Avianca Logo
4:25 am - 2:15 pm
PTY
-
SCL
8h 50m
1 stop
Avianca Logo
6:40 am - 5:00 pm
SCL
-
PTY
11h 20m
1 stop
$581Avianca
Tue, May 19 - Tue, May 26
Avianca Logo
4:25 am - 2:15 pm
PTY
-
SCL
8h 50m
1 stop
Avianca Logo
6:40 am - 5:00 pm
SCL
-
PTY
11h 20m
1 stop
$588Avianca
Thu, Apr 30 - Thu, May 7
Avianca Logo
10:10 am - 4:45 am
PTY
-
SCL
17h 35m
1 stop
Avianca Logo
6:40 am - 2:15 pm
SCL
-
PTY
8h 35m
1 stop
$589Avianca
Booking Insights

KAYAK's insights & trends for Panama City to Santiago flights

Get data-powered insights and trends into flights from Panama City to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Panama City to Santiago departing in May.

What’s the cheapest day of the week to fly from Panama City to Santiago?

The average price of all round-trip flights from Panama City to Santiago clicked on KAYAK for each day over the last 12 months.

When flying from Panama City to Santiago, you should consider leaving on a Monday and avoid Fridays if you are looking for the best rates. For your return to Panama City, you’ll find the best rates on Wednesdays and the most expensive ones on Mondays.

What is the cheapest month to fly from Panama City to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Santiago is March, where tickets cost $561 (return) on average. On the other hand, the most expensive months are September and August, where the average cost of round-trip tickets is $603 and $595 respectively.

Can I save money by flying with a layover from Panama City to Santiago?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $625, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Panama City to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Santiago, you should book around 3 weeks before departure, which saves you about 8% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 14 weeks before departure.

Good to know

Low seasonFebruary
Cheapest flight$289
Best time to beat the crowds with an average 2% drop in price.
Most popular time to fly with an average 2% increase in price.
Flight from Panama City to Santiago

When to book flights from Panama City to Santiago

Are your dates flexible? Find out the best times to travel from Panama City to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Santiago

  • What is the cheapest flight from Panama City to Santiago?

    In the last 3 days, the lowest price for a flight from Panama City to Santiago was $289 for a one-way ticket and $553 for a round-trip.

  • Do I need a passport to fly between Panama City and Santiago?

    Yes

  • Which aircraft models fly most regularly from Panama City to Santiago?

    The Boeing 737-800 is the aircraft model that flies most regularly on the Panama City to Santiago flight route.

  • Which airline alliances offer flights from Panama City to Santiago?

    Star Alliance is the only airline alliance operating flights between Panama City and Santiago.

  • On which days can I fly direct from Panama City to Santiago?

    There are nonstop flights from Panama City to Santiago on a daily basis.

  • Which is the best airline for flights from Panama City to Santiago, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Panama City to Santiago are Copa Airlines and Avianca. With an average price for the route of $592 and an overall rating of 7.5, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $605 and an overall rating of 6.5.

  • How does KAYAK find such low prices on flights from Panama City to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Panama City with another airline. Booking your flights between Panama City and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Santiago

  • Looking for a cheap flight? 25% of our users found flights on this route for $590 or less round-trip.

Prefer to fly direct from Panama City to Santiago?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to Santiago Arturo Merino Benitez.
Find which airlines fly direct from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Santiago Arturo Merino Benitez

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

Santiago Arturo Merino Benitez to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top airlines flying from Panama City to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1580 reviews
6.8Entertainment
7.8Boarding
7.4Comfort
8.1Crew
6.8Food
Airline reviews

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

10.0 ExcellentAnonymous, Apr 2026
DAV - PTY
Read more Copa Airlines reviews

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

Copa staff at PTY and one particular crew member were unhelpful & rude.

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

Some of the Air hostesses are not that friendly. Need improvement

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

This was my first time flying with you guys and my very last! This was the most horrible experience!!! There was not even tv in the plane! How cheap can this airline be!!! I paid so much for my suitcase!!! I would never fly with this airline again! The crew are very rude!

The crew was great! They waited for me as Air Canada flight was delayed by 1:15 hours from Ottawa to Toronto. I am a bit disappointed that we could only use wifi for entertainment but I survived! The only thing I would of liked is a more comfortable seat. The seat cushions are not thick enough for flights longer than 3 hours. Aside from that, everything was great.

After boarding, there was a small issue with the aircraft which caused a delay of about 45 minutes. During boarding and while passengers were being seated, the plane was being refueled. There were also a lot of unusual noises during the flight, which was not very reassuring. In addition, there was no WiFi or entertainment available.

Overall, the flight went well and the service was good. However, there was a very frightening moment during landing in Bogotá. Just as the plane was about to touch down, it suddenly went back up into the air. The aircraft was not descending straight and seemed to move left and right, which made the situation feel unstable. This was quite scary. After going back up, the plane circled for about 15 minutes before attempting to land again. Although I understand that safety always comes first and situations like this can happen, it was still a shocking experience for passengers.

The worst experience I've ever had because the "people" @ Avianca wouldn't let me fly because they said I needed a round trip ticket

I had bad experiences before now was excellent I am glad they have business class again

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

only a bag of chips and a bottle of water in business class was served

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

Everything you need to know for your flight from Panama City to Santiago

Information on your arrival and departure airports