SCL - SDQ

$317 Find Cheap Flights from Santiago to Santo Domingo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to Santo Domingo departing on 3/30. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santo Domingo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Santo Domingo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Santo Domingo, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$576
Overall average: $541
Avianca
Tue 3/24Tue 3/31
SCL - SDQ • 1 stop
Cheapest one-way
$317
Typical prices: $278-$329
Copa Airlines
Mon 3/30
SCL - SDQ • 1 stop
Top airlines
Avianca
Cheapest • from $576 (round-trip)
Copa Airlines
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Santiago and Santo Domingo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Panama City (PTY)
Cheapest • Avg $607 (round-trip)
Panama City (PTY)
Shortest trip • 10h 55m (one-way)
Insights
Insights
Insights
Insights
When to book
4 weeks
in advance
Our data shows that travelers who book at least 4 weeks in advance save around 12% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
August
Cheapest • 8% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santiago to Santo Domingo (SCL-SDQ)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to Santo Domingo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to Santo Domingo

Tue, Mar 24 - Tue, Mar 31
Avianca Logo
7:25 am - 4:50 pm
SCL
-
SDQ
10h 25m
1 stop
Avianca Logo
12:45 pm - 12:20 am
SDQ
-
SCL
10h 35m
1 stop
$576Avianca
Tue, Apr 14 - Tue, Apr 21
Avianca Logo
6:40 am - 5:55 pm
SCL
-
SDQ
11h 15m
1 stop
Avianca Logo
12:45 pm - 11:20 pm
SDQ
-
SCL
10h 35m
1 stop
$577Avianca
Thu, Jun 25 - Tue, Jul 7
Multiple Airlines Logo
3:35 am - 3:45 pm
SCL
-
SDQ
12h 10m
1 stop
Multiple Airlines Logo
1:45 pm - 2:35 am
SDQ
-
SCL
12h 50m
1 stop
$586Multiple Airlines
Sun, Apr 19 - Thu, May 21
Avianca Logo
6:40 am - 5:55 pm
SCL
-
SDQ
11h 15m
1 stop
Avianca Logo
12:45 pm - 4:45 am
SDQ
-
SCL
16h 00m
1 stop
$587Avianca
Mon, Jun 15 - Sun, Jun 28
Multiple Airlines Logo
5:00 am - 4:55 pm
SCL
-
SDQ
11h 55m
1 stop
Multiple Airlines Logo
3:25 pm - 3:55 am
SDQ
-
SCL
12h 30m
1 stop
$593Multiple Airlines
Sun, Apr 19 - Thu, May 21
Avianca Logo
6:40 am - 5:55 pm
SCL
-
SDQ
11h 15m
1 stop
Avianca Logo
12:45 pm - 11:20 pm
SDQ
-
SCL
10h 35m
1 stop
$601Avianca
Thu, Jul 9 - Sat, Aug 1
Copa Airlines Logo
2:27 am - 1:13 pm
SCL
-
SDQ
10h 46m
1 stop
Copa Airlines Logo
12:43 pm - 10:43 pm
SDQ
-
SCL
10h 00m
1 stop
$619Copa Airlines
Sun, Apr 19 - Thu, May 21
Avianca Logo
6:40 am - 11:50 am
SCL
-
SDQ
29h 10m
1 stop
Avianca Logo
12:45 pm - 4:45 am
SDQ
-
SCL
16h 00m
1 stop
$622Avianca
Thu, Mar 26 - Sun, Apr 5
Copa Airlines Logo
3:32 am - 4:14 pm
SCL
-
SDQ
13h 42m
1 stop
Copa Airlines Logo
12:38 pm - 3:00 am
SDQ
-
SCL
14h 22m
1 stop
$639Copa Airlines
Fri, Jul 24 - Tue, Aug 11
Multiple Airlines Logo
1:11 am - 6:39 pm
SCL
-
SDQ
17h 28m
2 stops
Multiple Airlines Logo
9:00 pm - 1:35 pm
SDQ
-
SCL
16h 35m
1 stop
$653Multiple Airlines
Booking Insights

KAYAK's insights & trends for Santiago to Santo Domingo flights

Get data-powered insights and trends into flights from Santiago to Santo Domingo to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Santiago to Santo Domingo?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santiago to Santo Domingo, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santiago to Santo Domingo is August, where tickets cost $533 (return) on average. On the other hand, the most expensive months are January and February, where the average cost of round-trip tickets is $703 and $659 respectively.

How far in advance should I book a flight from Santiago to Santo Domingo?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santiago to Santo Domingo, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santiago to Santo Domingo, you should book around 4 weeks before departure, which saves you about 12% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 21 weeks before departure.

Good to know

Low seasonAugust
Cheapest flight$317
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly with an average 11% increase in price.
Flight from Santiago to Santo Domingo

When to book flights from Santiago to Santo Domingo

Are your dates flexible? Find out the best times to travel from Santiago to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santiago to Santo Domingo

  • What is the cheapest flight from Santiago to Santo Domingo?

    In the last 3 days, the lowest price for a flight from Santiago to Santo Domingo was $317 for a one-way ticket and $576 for a round-trip.

  • Do I need a passport to fly between Santiago and Santo Domingo?

    Yes

  • Which aircraft models fly most regularly from Santiago to Santo Domingo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santiago to Santo Domingo?

    Star Alliance is the only airline alliance operating flights between Santiago and Santo Domingo.

  • Which is the best airline for flights from Santiago to Santo Domingo, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Santiago to Santo Domingo are Copa Airlines and Avianca. With an average price for the route of $558 and an overall rating of 7.5, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $590 and an overall rating of 6.5.

  • How does KAYAK find such low prices on flights from Santiago to Santo Domingo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to Santo Domingo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to Santo Domingo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santo Domingo from Santiago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to Santo Domingo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santo Domingo with an airline and back to Santiago with another airline. Booking your flights between Santiago and SDQ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to Santo Domingo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santo Domingo from Santiago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Santiago to Santo Domingo

  • Looking for a cheap flight? 25% of our users found flights on this route for $261 or less one-way.

Reviews of the top airlines flying from Santiago to Santo Domingo

 
See real verified KAYAK customer reviews for airlines flying from Santiago to Santo Domingo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to Santo Domingo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1559 reviews
6.8Food
7.4Comfort
8.1Crew
6.8Entertainment
7.8Boarding
Airline reviews

Copa staff at PTY and one particular crew member were unhelpful & rude.

6.0 GoodOluwaseyi, Feb 2026
PTY - POS
Read more Copa Airlines reviews

Copa staff at PTY and one particular crew member were unhelpful & rude.

Seats were awful. Media should have been included for such a long flight.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

I had bad experiences before now was excellent I am glad they have business class again

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

Provide free food and drinks on an international flight. Add updated head rests

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

We waited for one hour to deboard the plane after landing. That could be better

I like the crew members they're very friendly. Clean plane. The flight was on time. I dont like the comfort my car seat its better that the plane seats. They charge for everything. This airline was very good. Now it's a low cost airline

Not even water is offered on the flight. You cannot lean back on the seats and the seats are so narrow you can’t avoid rubbing elbows with the person next to you.

I couldnt recline the seat. Other than that crew was very attentive and helpful. Thsnk you

Everything you need to know for your flight from Santiago to Santo Domingo

Information on your arrival and departure airports