United States
USD

SCL - SDQ

$279 Find Cheap Flights from Santiago to Santo Domingo - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 19% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Everything you should know

Cheapest round-trip
$536
Typical prices: $588-$726
Avianca
Fri 11/23Sat 12/1
SCL - SDQ • 1 stop
Cheapest one-way
$279
Typical prices: $306-$389
Multiple Airlines
Sun 11/18
SCL - SDQ • 2 stops
Nonstop flights
Not available
There are currently no direct flights between Santiago and Santo Domingo. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
5 weeks
in advance
Our data shows that travelers who book at least 5 weeks in advance save around 11% compared to booking last minute.
Insights
Insights
When to travel
November
Cheapest • 16% price drop
January
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Punta Cana (PUJ)
Cheapest • Avg $557 (round-trip)
Panama City Tocumen Intl (PTY)
Shortest trip • 11h 30m (one-way)
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santo Domingo!

Cheap Flights from Santiago to Santo Domingo (SCL-SDQ)

 

Cheap flights from Santiago to Santo Domingo with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.

Tue, Nov 17 - Tue, Nov 24
Avianca Logo
7:30 am - 5:50 pmSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
11h 20m1 stop Bogotá El Dorado
Avianca Logo
6:45 pm - 5:45 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
10h 00m1 stop Bogotá El Dorado
$536Avianca
Wed, Nov 25 - Wed, Dec 2
Avianca Logo
7:30 am - 5:50 pmSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
11h 20m1 stop Bogotá El Dorado
Avianca Logo
12:45 pm - 5:45 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
16h 00m1 stop Bogotá El Dorado
$536Avianca
Mon, Nov 23 - Mon, Nov 30
Avianca Logo
7:30 am - 5:50 pmSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
11h 20m1 stop Bogotá El Dorado
Avianca Logo
12:45 pm - 1:05 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
11h 20m1 stop Bogotá El Dorado
$536Avianca
Wed, Nov 25 - Thu, Dec 3
Avianca Logo
2:10 am - 5:50 pmSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
16h 40m1 stop Bogotá El Dorado
Avianca Logo
12:45 pm - 1:05 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
11h 20m1 stop Bogotá El Dorado
$536Avianca
Sun, Feb 28 - Sun, Mar 7
Multiple Airlines Logo
1:33 pm - 9:41 amSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
21h 08m1 stop Lima J Chavez Intl
Multiple Airlines Logo
10:21 pm - 11:54 pmSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
48h 33m3 stops Lima J Chavez Intl Puerto Maldonado Cusco Velazco Astete
$550Multiple Airlines
Sun, Feb 28 - Sun, Mar 7
Multiple Airlines Logo
1:33 pm - 9:41 amSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
21h 08m1 stop Lima J Chavez Intl
Multiple Airlines Logo
10:21 pm - 11:54 pmSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
48h 33m2 stops Lima J Chavez Intl Cusco Velazco Astete
$555Multiple Airlines
Thu, Mar 4 - Thu, Mar 11
Multiple Airlines Logo
7:00 am - 8:40 amSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
26h 40m1 stop Lima J Chavez Intl
Multiple Airlines Logo
8:50 pm - 11:54 pmSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
50h 04m2 stops Lima J Chavez Intl Cusco Velazco Astete
$555Multiple Airlines
Sat, Dec 5 - Thu, Dec 10
Copa Airlines Logo
12:20 pm - 2:08 amSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
14h 48m1 stop Panama City Tocumen Intl
Copa Airlines Logo
7:03 pm - 5:52 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
9h 49m1 stop Panama City Tocumen Intl
$574Copa Airlines
Sat, Nov 21 - Sat, Nov 28
Copa Airlines Logo
5:07 am - 2:08 amSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
22h 01m1 stop Panama City Tocumen Intl
Copa Airlines Logo
7:06 pm - 12:19 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
28h 13m1 stop Panama City Tocumen Intl
$574Copa Airlines
Sat, Dec 5 - Sat, Dec 12
Copa Airlines Logo
12:20 pm - 11:42 amSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
24h 22m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:09 pm - 11:35 pmSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
10h 26m1 stop Panama City Tocumen Intl
$574Copa Airlines

Price, demand and travel trends for Santiago to Santo Domingo flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Santiago to Santo Domingo?

Round-trip flights from Santiago to Santo Domingo typically range from $588 to $726. The lowest price found in the past 5 days was $536, on Avianca.

What's the cheapest day of the week to fly from Santiago to Santo Domingo?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Santiago to Santo Domingo. It’s 4% cheaper than the average day, while Saturday is the most expensive, with prices 3% higher.

What’s the cheapest month to fly from Santiago to Santo Domingo?

•November is the cheapest month to fly from Santiago to Santo Domingo at $556 round-trip.
•January ($716) and December ($708) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 28% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Santiago to Santo Domingo the cheapest?

Flights from Santiago to Santo Domingo are cheapest 5 weeks before departure. Booking in this window typically costs about 11% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Key details for Santiago to Santo Domingo flights

Low season

October

Cheapest flight

$279
Beat the crowds with an average 56% drop in travelers.
The most popular month to fly with an average 10% increase in travelers.
One-way flight from Santiago to Santo Domingo

When to book flights from Santiago to Santo Domingo

Are your dates flexible? Find out the best times to travel from Santiago to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Santiago to Santo Domingo flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Santiago to Santo Domingo?

    Only Economy Class is available on flights from Santiago to Santo Domingo.

  • How long is a flight from Santiago to Santo Domingo?

    A nonstop flight from Santiago to Santo Domingo takes 00m, covering 3,579 miles.

  • Do I need a passport to fly from Santiago to Santo Domingo?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Santiago to Santo Domingo flight?

    Round-trip flights from Santiago to Santo Domingo range from $588 to $726, with an average of $664 over the past 12 months. Anything below $588 counts as a good deal.

  • How expensive are last-minute Santiago to Santo Domingo flights?

    Last-minute fares on this route (booked within two weeks of departure) run 4% above the $664 route average. Book 5 weeks before departure for the lowest fares.

  • Have flight prices from Santiago to Santo Domingo changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $536 to $5,121. That means the highest observed fare was about 10x higher than the lowest one.

  • How are flight prices from Santiago to Santo Domingo looking right now?

    One-way fares from Santiago to Santo Domingo are currently lower than usual. Average one-way flight prices are about $325, which is 5% below the typical average for this route.

  • What car rental options are available at Santo Domingo Las Americas Airport (SDQ)?

    Santo Domingo Las Americas Airport (SDQ) hosts 5 major car rental companies, with daily rates starting from around $7 for economy cars. Top options include:

    • Zezgo
    • America Car Rental
    • JUMBO CAR
    • Infinity Car Rental
    • Final Rentals

  • Which airports can I use when flying from Santiago to Santo Domingo?

    Flights from Santiago to Santo Domingo usually depart from Santiago Arturo Merino Benitez (SCL) and arrive at Santo Domingo Las Americas (SDQ).

  • Which airports do connecting flights from Santiago to Santo Domingo pass through?

    One-stop flights from Santiago to Santo Domingo most commonly connect through:

    • Panama City Tocumen Intl (PTY) - 69% of one-stop connections
    • Bogotá El Dorado (BOG) - 27% of one-stop connections
    • Punta Cana (PUJ) - 3% of one-stop connections
    • Lima J Chavez Intl (LIM) - 2% of one-stop connections

  • Can I save money by using flexible dates for flights from Santiago to Santo Domingo?

    Yes. Flexible dates can save you up to 7% on flights from Santiago to Santo Domingo. Wednesday is the cheapest departure day at $642 round-trip on average, while Saturday is the most expensive at $685, a difference of $43.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Santiago to Santo Domingo?

    Flying via Panama City Tocumen Intl (PTY) gives the shortest average 1-stop total travel time at 11h 30m, compared with 11h 31m via Bogotá El Dorado (BOG) and 12h 23m via Punta Cana (PUJ).

  • What is the time difference between Santiago and Santo Domingo?

    Santo Domingo is 1 hour behind Santiago (Atlantic Time vs Chile Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Santo Domingo?

    Some of the most popular sights in Santo Domingo are Catedral Primada de América, Centro Olimpico Juan Pablo Duarte and Palacio de los Deportes Virgilio Travieso Soto. These are among the most viewed places in Santo Domingo on KAYAK.

Your guide to booking Santiago to Santo Domingo flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Saturday. On this route, Wednesday flights average $642, about $43 less than Saturday fares (6% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 5 weeks before you fly. On this route, that window historically saves about 11% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Santiago to Santo Domingo trip for November. Fares historically average $556 round-trip in that month - typically $160 less than the most expensive month, which is January (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santo Domingo Las Americas Airport.

    • Hampton by Hilton Santo Domingo Airport

More options for your flight from Santiago to Santo Domingo

Complete your trip to Santo Domingo with a hotel stay or car rental

Car rentals in Santo Domingo
Hotels in Santo Domingo
Vacations in Santo Domingo