SDQ - SCL

$244 Find Cheap Flights from Santo Domingo to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to Santiago departing on 6/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to Santiago, as well as popular online travel agencies
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Cheap Flights from Santo Domingo to Santiago (SDQ-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to Santiago

Tue, Sep 2 - Wed, Sep 24
 Logo
2:05 pm - 2:35 amSDQ-SCL
12h 30m1 stop
 Logo
4:35 am - 3:20 pmSCL-SDQ
11h 45m1 stop
Wed, Aug 13 - Sun, Aug 17
Avianca Logo
6:10 pm - 4:15 amSDQ-SCL
10h 05m1 stop
Avianca Logo
6:10 am - 5:15 pmSCL-SDQ
11h 05m1 stop
$582Avianca
Find Deal
Fri, May 30 - Sun, Jun 15
Copa Airlines Logo
2:05 pm - 5:04 amSDQ-SCL
14h 59m1 stop
Copa Airlines Logo
2:24 am - 10:27 pmSCL-SDQ
20h 03m1 stop
$586Copa Airlines
Find Deal
Fri, Jun 20 - Sun, Jun 29
Copa Airlines Logo
2:05 pm - 2:47 amSDQ-SCL
12h 42m1 stop
Copa Airlines Logo
12:13 am - 4:17 pmSCL-SDQ
16h 04m1 stop
$865Copa Airlines
Find Deal
Wed, Aug 13 - Sat, Aug 16
 Logo
8:25 am - 11:08 pmSDQ-SCL
14h 43m2 stops
 Logo
2:23 am - 1:10 pmSCL-SDQ
10h 47m1 stop
Thu, Jul 3 - Wed, Jul 23
Copa Airlines Logo
8:55 am - 11:08 pmSDQ-SCL
14h 13m1 stop
Copa Airlines Logo
12:12 am - 1:10 pmSCL-SDQ
12h 58m1 stop
$1,088Copa Airlines
Find Deal
Thu, Nov 6 - Sun, Nov 16
United Airlines Logo
6:00 am - 8:50 amSDQ-SCL
25h 50m2 stops
United Airlines Logo
10:45 pm - 2:49 amSCL-SDQ
29h 04m2 stops
$1,881United Airlines
Find Deal
Mon, Nov 10 - Sat, Nov 15
United Airlines Logo
2:55 pm - 8:50 amSDQ-SCL
40h 55m2 stops
United Airlines Logo
10:45 pm - 2:49 amSCL-SDQ
29h 04m2 stops
$1,975United Airlines
Find Deal
Tue, Sep 2 - Wed, Sep 24
Delta Logo
6:00 am - 7:00 amSDQ-SCL
25h 00m2 stops
Delta Logo
11:00 am - 1:47 pmSCL-SDQ
27h 47m2 stops
$2,334Delta
Find Deal
Wed, Aug 13 - Thu, Aug 21
Delta Logo
6:00 am - 7:00 amSDQ-SCL
25h 00m2 stops
Delta Logo
11:00 am - 1:22 pmSCL-SDQ
26h 22m2 stops
$2,516Delta
Find Deal
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KAYAK's insights & trends for Santo Domingo to Santiago flights

Get data-powered insights and trends into flights from Santo Domingo to Santiago to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Santo Domingo to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santo Domingo to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santo Domingo to Santiago is October, where tickets cost $514 (return) on average. On the other hand, the most expensive months are February and January, where the average cost of round-trip tickets is $877 and $677 respectively.

How far in advance should I book a flight from Santo Domingo to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santo Domingo to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santo Domingo to Santiago, you should book around 2 weeks before departure. For the absolute cheapest price, our data suggests you should book 18 weeks before departure.

Good to know

Low seasonJune
High seasonDecember
Cheapest flight$244
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 9% increase in price.
Flight from Santo Domingo to Santiago

When to book flights from Santo Domingo to Santiago

Are your dates flexible? Find out the best times to travel from Santo Domingo to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santo Domingo to Santiago

  • What is the cheapest flight from Santo Domingo to Santiago?

    In the last 3 days, the lowest price for a flight from Santo Domingo to Santiago was $244 for a one-way ticket and $473 for a round-trip.

  • Do I need a passport to fly between Santo Domingo and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Santo Domingo and on arrival in Santiago.

  • Which aircraft models fly most regularly from Santo Domingo to Santiago?

    The Boeing 737 MAX 8 is the aircraft model that flies most regularly on the Santo Domingo to Santiago flight route.

  • Which airline alliances offer flights from Santo Domingo to Santiago?

    Star Alliance, and SkyTeam are the airline alliances operating flights between Santo Domingo and Santiago, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Santo Domingo to Santiago, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Santo Domingo to Santiago are Copa Airlines and Avianca. With an average price for the route of $652 and an overall rating of 7.5, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $566 and an overall rating of 6.7.

  • How does KAYAK find such low prices on flights from Santo Domingo to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Santo Domingo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Santo Domingo with another airline. Booking your flights between Santo Domingo and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Santo Domingo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top airlines flying from Santo Domingo to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1427 reviews
7.8Boarding
8.1Crew
6.8Food
6.8Entertainment
7.4Comfort
Airline reviews

The flight was delayed twice and I could not speak with anyone at the airport about checking in. The phone number to Copa - the customer service agents were polite. They are just limited at helping because they are not at the airport

2.0 MediocreAnonymous, May 2025PTY - MDE
Read more Copa Airlines reviews

The flight was delayed twice and I could not speak with anyone at the airport about checking in. The phone number to Copa - the customer service agents were polite. They are just limited at helping because they are not at the airport

We were in transit from Lima (flight at 1.10am) and we were in stand by in our flight from Panama to Washington. We wait from 4.30 am to 18.30pm in the Airport. The company give us 2 x 15 dollars for eat during the day and a personnal travel voucher of 400 dollars each. Do they buy food one time something in the Airport ??? And one of us live in France so the voucher is not usable. More than 24 hours travel !! And our place were near the toilets, with 8 children around us. The boy behind my seat stamped his feet on my back all the flight. Really Wonder full ! So we are totally unhappy with our travel. Thanks Copa Airlines....

It would have been better if they don't separate families in seating. We were seated in the aile row in the middle of a family of four. It would have been better if they they seat the family of four together than separated.

I upgraded myself to Business Class at the last minute so I had a DREAMS window seat. Seeing as I've never flown Business before everything was novel and fun for me and it made the 7 hour flight much more enjoyable for sure.

No headphones given for inflight entertainment. I missed my flight from the previous day and the customer service agent tried to extort an additional $100.00 US from me for missing my flight. Really?!

Great from check in all the way to the end. Very happy with Copa

Copa stranded us ans then tried to charge us thousands to leave Panama.

Well the airline was fine. The only thing is I was charged for a checked in luggage. But when I reserved the ticket it showed a check in bag allowed. Who can I get in contact with for reimbursement.? The airline said I had to speak to whoever I booked ticket with.

Friendly flight team and seamless travel from one stop to next.

I loved my experience. Very safe, Very informative and very friendly.

Late departure. When the flight arrived in Medellin the plane sat at the gate for 20 minutes waiting for a bus for us to get off the plane.

I receive a service for what I pay, so it is fair.

A few years ago long flights 6 hours or so used to have video screens and they offered ear phones. The food cart used to come and drinks. Now absolutely nothing. Avianca is as bad as Spirit Airlines. Avianca will now be my last choice when booking my next flight.

Boarding was somewhat confusing in that the wrong messages were being displayed at the gate. It was somewhat annoying that I got off one flight and straight onto another (from the same gate), but in between they re-checked my hand luggage and made me get rid of my water (which they charge for on the plane). I was sitting in their 'Plus' seating, but the leg room was still too small to be able to sit square. The food options on the flights are pretty cheap quality (but not price). They got me from 'A' to 'B' on-time and for a relatively good price, but the experience itself was below average.

Lounge for business was closed. Boarding was rush and stand by. Seat for business is just the middle seat blocked and some more leg room.

Flew with our two children. Paid $380 to check two bags (one was overweight). They then left the bags behind on Sunday, December 21st, with all our family’s clothes and family Christmas presents. When we arrived at our destination they told us the bags had not arrived, and they thought (but didn’t know) they were still in Boston, but that there’d be a flight the next day and the bags would arrive the next day. The next day we found out there was no flight, now we’re hoping we get our bags before we fly back out. Meanwhile, trying to get any engagement or accurate information is a waste of time. The folks at the call center are just gatekeepers, who can’t connect with any departments that actually do things to solve a problem. Getting information is made deliberately difficult. My biggest regret is that I’ve had a number of awful experiences with Avianca traveling between the US and Colombia, and still let myself get suckered into buying these tickets because the schedule was great. Never again.

We were not aware carry-on bags cost extra until we arrived at the airport so, we were charged $240.00 for two small carry- on bags! There was a substantial fee for drinks and snacks. No wifi, or other entertainment was available. Waiting areas were crowded and uncomfortable.

I enjoyed it! In that case, I should have been offered this choice. On my first trip to Miami, I was asked to pay $320 for my luggage just for getting it totally broken. I cannot accept this situation at all!!!!

Overpriced checked bag price of $120 and they charge you for carryon if the size is not minimal of $120.

The connection time is too short to pass through customs and once you do clear customs the connecting flight is in another terminal that is not close.

Everything you need to know for your flight from Santo Domingo to Santiago

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