SDQ - SCL

$253 Find Cheap Flights from Santo Domingo to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to Santiago departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to Santiago, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$681
Typical prices: $656-$785
Multiple Airlines
Sun 1/18Sun 1/25
SDQ - SCL • 1 stop
Cheapest one-way
$253
Typical prices: $323-$430
Multiple Airlines
Thu 1/8
SDQ - SCL • 1 stop
Top airlines
Copa Airlines
Cheapest • from $717 (round-trip)
Copa Airlines
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
October
Cheapest • 9% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santo Domingo to Santiago (SDQ-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to Santiago

Sun, Jan 18 - Sun, Jan 25
Multiple Airlines Logo
8:50 pm - 10:39 am
SDQ
-
SCL
12h 49m1 stop
Multiple Airlines Logo
9:05 pm - 8:42 am
SCL
-
SDQ
12h 37m1 stop
$681Multiple Airlines
Fri, Jan 2 - Fri, Jan 9
Multiple Airlines Logo
9:10 am - 11:40 pm
SDQ
-
SCL
13h 30m1 stop
Multiple Airlines Logo
6:00 am - 4:45 pm
SCL
-
SDQ
11h 45m1 stop
$706Multiple Airlines
Fri, Mar 20 - Sun, Mar 22
Copa Airlines Logo
8:48 am - 3:17 am
SDQ
-
SCL
17h 29m1 stop
Copa Airlines Logo
3:32 am - 1:11 pm
SCL
-
SDQ
10h 39m1 stop
$717Copa Airlines
Sun, Jan 18 - Sun, Jan 25
Multiple Airlines Logo
7:35 am - 1:09 am
SDQ
-
SCL
16h 34m2 stops
Multiple Airlines Logo
9:05 pm - 8:42 am
SCL
-
SDQ
12h 37m1 stop
$739Multiple Airlines
Thu, Jan 22 - Wed, Jan 28
Avianca Logo
12:20 pm - 12:30 am
SDQ
-
SCL
11h 10m1 stop
Avianca Logo
7:35 am - 4:50 pm
SCL
-
SDQ
10h 15m1 stop
$741Avianca
Fri, Jan 30 - Fri, Feb 6
Avianca Logo
5:45 pm - 5:30 am
SDQ
-
SCL
10h 45m1 stop
Avianca Logo
1:35 am - 4:50 pm
SCL
-
SDQ
16h 15m1 stop
$752Avianca
Fri, Jan 30 - Sat, Feb 7
Multiple Airlines Logo
10:19 am - 6:40 am
SDQ
-
SCL
19h 21m2 stops
Multiple Airlines Logo
8:42 pm - 1:50 pm
SCL
-
SDQ
18h 08m1 stop
$765Multiple Airlines
Fri, Jan 30 - Sat, Feb 7
Multiple Airlines Logo
10:19 am - 10:15 pm
SDQ
-
SCL
34h 56m2 stops
Multiple Airlines Logo
7:05 pm - 9:53 am
SCL
-
SDQ
15h 48m2 stops
$770Multiple Airlines
Sun, Jan 18 - Sun, Jan 25
Multiple Airlines Logo
7:35 am - 1:09 am
SDQ
-
SCL
16h 34m2 stops
Multiple Airlines Logo
9:05 pm - 4:29 pm
SCL
-
SDQ
20h 24m2 stops
$814Multiple Airlines
Fri, Jan 30 - Sat, Feb 7
Multiple Airlines Logo
10:19 am - 12:15 pm
SDQ
-
SCL
24h 56m3 stops
Multiple Airlines Logo
12:35 pm - 11:20 pm
SCL
-
SDQ
35h 45m2 stops
$888Multiple Airlines
Booking Insights

KAYAK's insights & trends for Santo Domingo to Santiago flights

Get data-powered insights and trends into flights from Santo Domingo to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santo Domingo to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santo Domingo to Santiago departing in January.

What is the cheapest month to fly from Santo Domingo to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santo Domingo to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santo Domingo to Santiago is October, where tickets cost $576 (return) on average. On the other hand, the most expensive months are February and December, where the average cost of round-trip tickets is $877 and $744 respectively.

Can I save money by flying with a layover from Santo Domingo to Santiago?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $575, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Santo Domingo to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santo Domingo to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santo Domingo to Santiago, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 18 weeks before departure.

Good to know

Low seasonApril
Cheapest flight$253
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly with an average 16% increase in price.
Flight from Santo Domingo to Santiago

When to book flights from Santo Domingo to Santiago

Are your dates flexible? Find out the best times to travel from Santo Domingo to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santo Domingo to Santiago

  • What is the cheapest flight from Santo Domingo to Santiago?

    In the last 3 days, the lowest price for a flight from Santo Domingo to Santiago was $253 for a one-way ticket and $681 for a round-trip.

  • Do I need a passport to fly between Santo Domingo and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Santo Domingo and on arrival in Santiago.

  • Which aircraft models fly most regularly from Santo Domingo to Santiago?

    The Boeing 737 MAX 8 is the aircraft model that flies most regularly on the Santo Domingo to Santiago flight route.

  • Which airline alliances offer flights from Santo Domingo to Santiago?

    Star Alliance is the only airline alliance operating flights between Santo Domingo and Santiago.

  • Which is the best airline for flights from Santo Domingo to Santiago, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Santo Domingo to Santiago are Copa Airlines and Avianca. With an average price for the route of $733 and an overall rating of 7.6, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $605 and an overall rating of 6.6.

  • How does KAYAK find such low prices on flights from Santo Domingo to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Santo Domingo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Santo Domingo with another airline. Booking your flights between Santo Domingo and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Santo Domingo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Santo Domingo to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1554 reviews
7.8Boarding
6.9Food
8.1Crew
6.8Entertainment
7.4Comfort
Airline reviews

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

8.0 ExcellentTisagh, Nov 2025
SDQ - PTY
Read more Copa Airlines reviews

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Some of the Air hostesses are not that friendly. Need improvement

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

Very happy with my flight. I would definitely recommend it.

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

I like the crew they're very friendly. I don't like. on five hour flight they not offered snacks. Any drink. Not even coffee

Not even water is offered on the flight. You cannot lean back on the seats and the seats are so narrow you can’t avoid rubbing elbows with the person next to you.

I couldnt recline the seat. Other than that crew was very attentive and helpful. Thsnk you

Did not fly with Pakistan International Airlines. Have never flown with Pakistan International Airlines.

The usb plugs for charging your phone didn’t work, the seats were coarse and hard. Not very comfortable. No inflight WiFi

Very uncomfortable planes , poor service on the plane , take your own water so you don’t dehydrate , in a 6 hs flight they sold one time food and beverage . 1 plane was delayed 6 hs , I lost a connecting flight . Then in the way back they announce a delay of 2 hs so I had to take a different flight to arrive on time for my connecting flight . Avoid this airline .

why did we have to go through security mid flight

The incoming plane was late and no information was shared. They even announced we would board in 10 muntes 40 minutes prior to the plane arriving, and the website said until takeoff that we had taken off an hour earlier

Boarding was excessively slow. They do it by groups in a way that it doesn’t make sense. After business class , ppl that need assistance and any other priority group they should have ppl board from the back to the front. First rows 20+. Then 15+. Then 10, etc. having ppl sitting in the back board last makes no sense. The libe backame long as soon as ppl on rows 10 or so where told to board. The line went all the way up the ramp and tunnel for 25 mins.

Seats are very tight even in Plus, no complimentary snacks or beverage

Everything you need to know for your flight from Santo Domingo to Santiago

Information on your arrival and departure airports