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SDQ - SCL

$361 Find Cheap Flights from Santo Domingo to Santiago - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$534
Typical prices: $647-$819
Multiple Airlines
Sat 2/10Sat 3/10
SDQ - SCL • 1 stop
Cheapest one-way
$263
Typical prices: $338-$447
Multiple Airlines
Thu 11/1
SDQ - SCL • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Santo Domingo and Santiago. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
26 weeks
in advance
Our data shows that travelers who book at least 26 weeks in advance save around 30% compared to booking last minute.
Insights
Insights
When to travel
March
Cheapest • 5% price drop
November
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Punta Cana (PUJ)
Cheapest • Avg $564 (round-trip)
Bogotá El Dorado (BOG)
Shortest trip • 11h 16m (one-way)
Insights
Insights
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Cheap Flights from Santo Domingo to Santiago (SDQ-SCL)

 

Cheap flights from Santo Domingo to Santiago with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.

Wed, Feb 10 - Wed, Mar 10
Multiple Airlines Logo
8:05 pm - 10:53 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
13h 48m1 stop Lima J Chavez Intl
Multiple Airlines Logo
8:35 pm - 7:10 amSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
11h 35m1 stop Lima J Chavez Intl
$534Multiple Airlines
Tue, Dec 1 - Sat, Dec 12
Multiple Airlines Logo
1:40 pm - 3:35 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
12h 55m1 stop Punta Cana
Multiple Airlines Logo
9:25 am - 9:40 pmSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
13h 15m1 stop Punta Cana
$639Multiple Airlines
Wed, Nov 18 - Tue, Nov 24
Multiple Airlines Logo
8:05 pm - 5:05 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
32h 00m1 stop Lima J Chavez Intl
Multiple Airlines Logo
2:13 am - 11:57 pmSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
22h 44m1 stop Medellín Jose Maria Cordova Intl
$671Multiple Airlines
Thu, Jan 21 - Tue, Jan 26
Multiple Airlines Logo
8:50 pm - 12:40 pmSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
14h 50m1 stop Lima J Chavez Intl
Multiple Airlines Logo
10:12 pm - 7:10 amSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
33h 58m1 stop Lima J Chavez Intl
$673Multiple Airlines
Mon, Nov 2 - Fri, Nov 6
Avianca Logo
6:45 pm - 5:45 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
10h 00m1 stop Bogotá El Dorado
Avianca Logo
2:10 am - 11:50 amSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
10h 40m1 stop Bogotá El Dorado
$759Avianca
Tue, Nov 3 - Mon, Nov 9
Avianca Logo
12:45 pm - 5:45 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
16h 00m1 stop Bogotá El Dorado
Avianca Logo
2:10 am - 11:50 amSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
10h 40m1 stop Bogotá El Dorado
$759Avianca
Mon, Nov 2 - Fri, Nov 6
Avianca Logo
6:45 pm - 5:45 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
10h 00m1 stop Bogotá El Dorado
Avianca Logo
2:10 am - 5:50 pmSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
16h 40m1 stop Bogotá El Dorado
$759Avianca
Thu, Nov 5 - Tue, Nov 10
Copa Airlines Logo
5:55 am - 3:38 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
20h 43m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:15 pm - 11:07 amSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
23h 52m1 stop Panama City Tocumen Intl
$761Copa Airlines
Tue, Oct 27 - Mon, Nov 2
Copa Airlines Logo
5:55 am - 2:46 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
19h 51m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:15 pm - 11:07 amSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
23h 52m1 stop Panama City Tocumen Intl
$761Copa Airlines
Tue, Oct 27 - Mon, Nov 2
Copa Airlines Logo
7:07 pm - 5:55 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
9h 48m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:15 pm - 2:08 amSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
14h 53m1 stop Panama City Tocumen Intl
$761Copa Airlines

Price, demand and travel trends for Santo Domingo to Santiago flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

What's the cheapest day of the week to fly from Santo Domingo to Santiago?

Based on deals KAYAK users found in the last 12 months, Thursday is the cheapest day of the week to fly from Santo Domingo to Santiago. It’s 5% cheaper than the average day, while Friday is the most expensive, with prices 8% higher.

What’s the cheapest month to fly from Santo Domingo to Santiago?

•March is the cheapest month to fly from Santo Domingo to Santiago at $692 round-trip.
•January ($786) and December ($783) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 13% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Santo Domingo to Santiago the cheapest?

Flights from Santo Domingo to Santiago are cheapest 26 weeks before departure. Booking in this window typically costs about 30% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

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Key details for Santo Domingo to Santiago flights

Low season

February

Cheapest flight

$263
Beat the crowds with an average 44% drop in travelers.
One-way flight from Santo Domingo to Santiago

When to book flights from Santo Domingo to Santiago

Are your dates flexible? Find out the best times to travel from Santo Domingo to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Santo Domingo to Santiago flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Santo Domingo to Santiago?

    Only Economy Class is available on flights from Santo Domingo to Santiago.

  • How long is a flight from Santo Domingo to Santiago?

    A nonstop flight from Santo Domingo to Santiago takes 00m, covering 3,579 miles.

  • Do I need a passport to fly from Santo Domingo to Santiago?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Santo Domingo to Santiago flight?

    Round-trip flights from Santo Domingo to Santiago range from $647 to $819, with an average of $728 over the past 12 months. Anything below $647 counts as a good deal.

  • How expensive are last-minute Santo Domingo to Santiago flights?

    Last-minute fares on this route (booked within two weeks of departure) run 9% above the $728 route average. Book 26 weeks before departure for the lowest fares.

  • How are flight prices from Santo Domingo to Santiago looking right now?

    One-way fares from Santo Domingo to Santiago are currently higher than usual. Average one-way flight prices are about $413, which is 6% above the typical average for this route.

  • What car rental options are available at Santiago Arturo Merino Benitez Airport (SCL)?

    Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car rental companies, with daily rates starting from around $6 for economy cars. Top options include:

    • Lucano
    • United Rent-A-Car
    • Rosselot
    • FlexWays
    • Alamo

  • Which airports can I use when flying from Santo Domingo to Santiago?

    Flights from Santo Domingo to Santiago usually depart from Santo Domingo Las Americas (SDQ) and arrive at Santiago Arturo Merino Benitez (SCL).

  • Which airports do connecting flights from Santo Domingo to Santiago pass through?

    One-stop flights from Santo Domingo to Santiago most commonly connect through:

    • Panama City Tocumen Intl (PTY) - 42% of one-stop connections
    • Bogotá El Dorado (BOG) - 41% of one-stop connections
    • Punta Cana (PUJ) - 11% of one-stop connections
    • Lima J Chavez Intl (LIM) - 5% of one-stop connections

  • Can I save money by using flexible dates for flights from Santo Domingo to Santiago?

    Yes. Flexible dates can save you up to 12% on flights from Santo Domingo to Santiago. Thursday is the cheapest departure day at $697 round-trip on average, while Friday is the most expensive at $787, a difference of $90.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Santo Domingo to Santiago?

    Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time at 11h 16m, compared with 11h 20m via Panama City Tocumen Intl (PTY) and 12h 32m via Punta Cana (PUJ).

  • What is the time difference between Santo Domingo and Santiago?

    Santiago is 1 hour ahead of Santo Domingo (Chile Time vs Atlantic Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Santiago?

    Some of the most popular sights in Santiago are Estadio Nacional Julio Martinez Pradanos, Espacio Riesco Convention and Exhibition Center and Costanera Center. These are among the most viewed places in Santiago on KAYAK.

Your guide to booking Santo Domingo to Santiago flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Thursday departure and avoid flying on Friday. On this route, Thursday flights average $697, about $90 less than Friday fares (11% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 26 weeks before you fly. On this route, that window historically saves about 30% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Santo Domingo to Santiago trip for March. Fares historically average $692 round-trip in that month - typically $94 less than the most expensive month, which is January (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santiago Arturo Merino Benitez Airport.

    • Holiday Inn Santiago - Airport Terminal By IHG

More options for your flight from Santo Domingo to Santiago

Complete your trip to Santiago with a hotel stay or car rental

Car rentals in Santiago
Hotels in Santiago
Vacations in Santiago