SDQ - SCL

$227 Find Cheap Flights from Santo Domingo to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to Santiago departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to Santiago, as well as popular online travel agencies
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41.299.237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$459
Typical prices: $610-$539
Multiple Airlines
Thu 8/20Mon 8/24
SDQ - SCL • 1 stop
Cheapest one-way
$227
Typical prices: $280-$361
Multiple Airlines
Tue 5/19
SDQ - SCL • 1 stop
When to book
in advance
Our data shows that travelers who book at least 2 weeks in advance save around 10% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 10% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santo Domingo to Santiago (SDQ-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to Santiago

Thu, Aug 20 - Mon, Aug 24
Multiple Airlines Logo
1:45 pm - 2:35 am
SDQ
-
SCL
12h 50m
1 stop
Multiple Airlines Logo
5:00 am - 4:55 pm
SCL
-
SDQ
11h 55m
1 stop
$459Multiple Airlines
Fri, Sep 11 - Wed, Sep 16
Multiple Airlines Logo
8:55 am - 11:55 pm
SDQ
-
SCL
14h 00m
1 stop
Multiple Airlines Logo
4:35 am - 3:55 pm
SCL
-
SDQ
12h 20m
1 stop
$471Multiple Airlines
Thu, Jul 23 - Mon, Jul 27
Multiple Airlines Logo
1:45 pm - 2:35 am
SDQ
-
SCL
12h 50m
1 stop
Multiple Airlines Logo
5:00 am - 4:55 pm
SCL
-
SDQ
11h 55m
1 stop
$480Multiple Airlines
Fri, Sep 11 - Wed, Sep 16
Multiple Airlines Logo
8:55 am - 11:55 pm
SDQ
-
SCL
14h 00m
1 stop
Multiple Airlines Logo
4:35 am - 3:55 pm
SCL
-
SDQ
12h 20m
1 stop
$532Multiple Airlines
Thu, Jul 16 - Mon, Jul 27
Multiple Airlines Logo
1:45 pm - 2:35 am
SDQ
-
SCL
12h 50m
1 stop
Multiple Airlines Logo
5:00 am - 4:55 pm
SCL
-
SDQ
11h 55m
1 stop
$579Multiple Airlines
Fri, Oct 9 - Mon, Oct 19
Multiple Airlines Logo
6:13 pm - 9:29 pm
SDQ
-
SCL
26h 16m
1 stop
Multiple Airlines Logo
6:00 am - 4:55 pm
SCL
-
SDQ
11h 55m
1 stop
$604Multiple Airlines
Fri, Sep 18 - Mon, Sep 28
Multiple Airlines Logo
8:55 am - 11:55 pm
SDQ
-
SCL
14h 00m
1 stop
Multiple Airlines Logo
6:00 am - 4:55 pm
SCL
-
SDQ
11h 55m
1 stop
$615Multiple Airlines
Thu, Oct 8 - Mon, Oct 19
Multiple Airlines Logo
9:00 pm - 2:45 pm
SDQ
-
SCL
16h 45m
1 stop
Multiple Airlines Logo
6:00 am - 4:55 pm
SCL
-
SDQ
11h 55m
1 stop
$631Multiple Airlines
Sun, Oct 11 - Fri, Oct 16
Multiple Airlines Logo
1:55 pm - 4:55 am
SDQ
-
SCL
14h 00m
1 stop
Multiple Airlines Logo
4:35 am - 3:45 pm
SCL
-
SDQ
12h 10m
1 stop
$637Multiple Airlines
Tue, May 5 - Mon, May 18
Multiple Airlines Logo
1:45 pm - 2:35 am
SDQ
-
SCL
12h 50m
1 stop
Multiple Airlines Logo
5:00 am - 4:55 pm
SCL
-
SDQ
11h 55m
1 stop
$661Multiple Airlines
Booking Insights

KAYAK's insights & trends for Santo Domingo to Santiago flights

Get data-powered insights and trends into flights from Santo Domingo to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santo Domingo to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santo Domingo to Santiago departing in August.

What is the cheapest month to fly from Santo Domingo to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santo Domingo to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santo Domingo to Santiago is August, where tickets cost $582 (return) on average. On the other hand, the most expensive months are January and December, where the average cost of round-trip tickets is $785 and $758 respectively.

Can I save money by flying with a layover from Santo Domingo to Santiago?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $416 on average.

How far in advance should I book a flight from Santo Domingo to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santo Domingo to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santo Domingo to Santiago, you should book around 2 weeks before departure, which saves you about 10% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 18 weeks before departure.

Good to know

Low seasonApril
Cheapest flight$227
Best time to beat the crowds but there is an average 9% increase in price.
Most popular time to fly with an average 17% increase in price.
Flight from Santo Domingo to Santiago

When to book flights from Santo Domingo to Santiago

Are your dates flexible? Find out the best times to travel from Santo Domingo to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santo Domingo to Santiago

  • What is the cheapest flight from Santo Domingo to Santiago?

    In the last 3 days, the lowest price for a flight from Santo Domingo to Santiago was $227 for a one-way ticket and $459 for a round-trip.

  • Do I need a passport to fly between Santo Domingo and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Santo Domingo and on arrival in Santiago.

  • Which aircraft models fly most regularly from Santo Domingo to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santo Domingo to Santiago?

    Star Alliance is the only airline alliance operating flights between Santo Domingo and Santiago.

  • Which is the best airline for flights from Santo Domingo to Santiago, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Santo Domingo to Santiago are Copa Airlines and Avianca. With an average price for the route of $778 and an overall rating of 7.5, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $657 and an overall rating of 6.5.

  • How does KAYAK find such low prices on flights from Santo Domingo to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Santo Domingo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Santo Domingo with another airline. Booking your flights between Santo Domingo and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Santo Domingo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Santo Domingo to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1575 reviews
8.1Crew
6.8Entertainment
7.8Boarding
6.8Food
7.4Comfort
Airline reviews

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

10.0 ExcellentSasha, Mar 2026
ASU - PTY
Read more Copa Airlines reviews

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

Seats were awful. Media should have been included for such a long flight.

A lot things happened in this trip.The fly should be less stress.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Some of the Air hostesses are not that friendly. Need improvement

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

They should provide water to passengers who ask for it

The worst experience I've ever had because the "people" @ Avianca wouldn't let me fly because they said I needed a round trip ticket

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral and avianca lost my check in luggage

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I upgraded to businesses class. Because of that the flight was comfortable.

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

The flight attendant smashed her beverage cart into my knee, causing significant amount of pain. The seats were extremely uncomfortable. No food or drink is offered unless you want to pay the ridiculous prices for it. The schedule of flying in the overnight hours is also very uncomfortable.

We waited for one hour to deboard the plane after landing. That could be better

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

Everything you need to know for your flight from Santo Domingo to Santiago

Information on your arrival and departure airports