$311 Find Cheap Flights from Santo Domingo to Missouri - Compare and Save
This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to Missouri departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
Flight Deals
Cheap Flights from Santo Domingo to Missouri
Cheapest round-trip prices found by our users on KAYAK in the last 5 daysNonstop only
Weekend trip
Sort by: Cheapest
St. Louis
11h 19m4 stops
from $721per person
Book Cheap Santo Domingo to Missouri Plane Tickets
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to Missouri that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.
Recent round-trip flight deals from Santo Domingo to Missouri
Fri, Dec 18 - Tue, Jan 5
7:00 am - 6:52 pmSDQ Santo Domingo Las Americas-MCI Kansas City
13h 52m1 stop New York John F Kennedy Intl
10:20 am - 12:30 amMCI Kansas City-SDQ Santo Domingo Las Americas
12h 10m2 stops Detroit Metropolitan Wayne County New York John F Kennedy Intl
$675Delta
Fri, Dec 18 - Tue, Jan 5
4:18 pm - 9:46 pmSDQ Santo Domingo Las Americas-MCI Kansas City
31h 28m2 stops Newark Chicago O'Hare Intl
6:00 am - 3:06 pmMCI Kansas City-SDQ Santo Domingo Las Americas
31h 06m2 stops Chicago O'Hare Intl Newark
$683United Airlines
Fri, Dec 18 - Tue, Jan 5
5:07 pm - 12:51 amSDQ Santo Domingo Las Americas-MCI Kansas City
9h 44m1 stop Miami
5:23 pm - 11:51 amMCI Kansas City-SDQ Santo Domingo Las Americas
16h 28m1 stop Miami
$694American Airlines
Sat, Nov 14 - Tue, Nov 24
3:57 pm - 10:10 pmSDQ Santo Domingo Las Americas-MCI Kansas City
8h 13m1 stop Atlanta Hartsfield-Jackson
11:40 am - 2:14 amMCI Kansas City-SDQ Santo Domingo Las Americas
12h 34m1 stop New York John F Kennedy Intl
$698Delta
Sat, Nov 14 - Tue, Nov 24
7:02 am - 7:03 pmSDQ Santo Domingo Las Americas-MCI Kansas City
14h 01m1 stop New York John F Kennedy Intl
11:40 am - 2:14 amMCI Kansas City-SDQ Santo Domingo Las Americas
12h 34m1 stop New York John F Kennedy Intl
$698Delta
Sat, Nov 14 - Tue, Nov 24
7:02 am - 8:51 pmSDQ Santo Domingo Las Americas-MCI Kansas City
15h 49m2 stops New York John F Kennedy Intl Detroit Metropolitan Wayne County
11:40 am - 2:14 amMCI Kansas City-SDQ Santo Domingo Las Americas
12h 34m1 stop New York John F Kennedy Intl
$698Delta
Wed, Nov 11 - Wed, Dec 9
3:55 pm - 11:59 pmSDQ Santo Domingo Las Americas-MCI Kansas City
10h 04m1 stop Miami
5:20 am - 7:53 pmMCI Kansas City-SDQ Santo Domingo Las Americas
12h 33m2 stops Dallas/Fort Worth Miami
$705American Airlines
Wed, Nov 11 - Wed, Dec 9
7:00 am - 8:50 pmSDQ Santo Domingo Las Americas-MCI Kansas City
15h 50m2 stops Miami Philadelphia
6:55 am - 7:53 pmMCI Kansas City-SDQ Santo Domingo Las Americas
10h 58m2 stops Chicago O'Hare Intl Miami
$705American Airlines
Wed, Nov 11 - Wed, Dec 9
12:59 pm - 11:59 pmSDQ Santo Domingo Las Americas-MCI Kansas City
13h 00m1 stop Miami
1:15 pm - 10:05 amMCI Kansas City-SDQ Santo Domingo Las Americas
18h 50m1 stop Miami
$715American Airlines
Fri, Nov 20 - Mon, Nov 30
6:00 am - 9:50 pmSDQ Santo Domingo Las Americas-STL Lambert-St Louis
17h 50m1 stop Miami
6:15 pm - 3:51 pmSTL Lambert-St Louis-SDQ Santo Domingo Las Americas
19h 36m1 stop Miami
$721American Airlines
Recent one-way flight deals from Santo Domingo to Missouri
Sat, Oct 24
12:42 pm - 11:13 pmSDQ Santo Domingo Las Americas-STL Lambert-St Louis
11h 31m2 stops San Juan Luis Munoz Marin Intl Orlando
$311Frontier
Sat, Oct 24
3:30 pm - 7:15 pmSDQ Santo Domingo Las Americas-STL Lambert-St Louis
52h 45m3 stops San Juan Luis Munoz Marin Intl Miami Denver Intl
$319Multiple Airlines
Sat, Nov 21
3:35 pm - 7:34 pmSDQ Santo Domingo Las Americas-MCI Kansas City
29h 59m2 stops Miami Denver Intl
$337Multiple Airlines
Mon, Oct 19
10:19 am - 3:24 pmSDQ Santo Domingo Las Americas-STL Lambert-St Louis
54h 05m3 stops Miami Atlanta Hartsfield-Jackson Denver Intl
$361Multiple Airlines
Sat, Nov 21
3:35 pm - 7:34 pmSDQ Santo Domingo Las Americas-MCI Kansas City
29h 59m3 stops Miami Atlanta Hartsfield-Jackson Denver Intl
$362Multiple Airlines
Mon, Oct 19
7:10 pm - 5:40 pmSDQ Santo Domingo Las Americas-STL Lambert-St Louis
47h 30m2 stops Newark Atlanta Hartsfield-Jackson
$370Multiple Airlines
Mon, Nov 23
7:30 am - 12:34 pmSDQ Santo Domingo Las Americas-MCI Kansas City
55h 04m3 stops San Juan Luis Munoz Marin Intl Miami Las Vegas Harry Reid Intl
$381Multiple Airlines
Tue, Jan 26
3:40 pm - 10:32 pmSDQ Santo Domingo Las Americas-SGF Springfield-Branson
8h 52m1 stop Atlanta Hartsfield-Jackson
$383Delta
Tue, Jan 26
10:58 am - 11:02 pmSDQ Santo Domingo Las Americas-SGF Springfield-Branson
14h 04m2 stops Miami Chicago O'Hare Intl
$439American Airlines
Tue, Jan 26
10:58 am - 11:02 pmSDQ Santo Domingo Las Americas-SGF Springfield-Branson
14h 04m2 stops Miami Chicago O'Hare Intl
$440American Airlines
Recent last minute flight deals from Santo Domingo to Missouri
Wed, Oct 7 - Mon, Oct 12
2:33 pm - 10:59 pmSDQ Santo Domingo Las Americas-MCI Kansas City
9h 26m1 stop Miami
11:56 am - 12:35 pmMCI Kansas City-SDQ Santo Domingo Las Americas
23h 39m1 stop Philadelphia
$986American Airlines
Wed, Oct 7 - Mon, Oct 12
7:00 am - 7:53 pmSDQ Santo Domingo Las Americas-MCI Kansas City
13h 53m2 stops Miami Dallas/Fort Worth
5:10 pm - 1:33 pmMCI Kansas City-SDQ Santo Domingo Las Americas
19h 23m1 stop Miami
$990American Airlines
Wed, Oct 7 - Mon, Oct 12
10:27 am - 11:58 pmSDQ Santo Domingo Las Americas-MCI Kansas City
14h 31m2 stops Miami Charlotte Douglas
5:20 pm - 9:22 amMCI Kansas City-SDQ Santo Domingo Las Americas
15h 02m2 stops Dallas/Fort Worth Miami
$990American Airlines
Booking Insights
KAYAK's insights & trends for Santo Domingo to Missouri flights
Get data-powered insights and trends into flights from Santo Domingo to Missouri to help you find the cheapest flights, the best time to fly and much more.
Prices
Airlines
FAQs - booking Missouri flights
Reviews of the top airline flying from Santo Domingo to Missouri
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to Missouri. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
7.0
American AirlinesOverall score based on 12096 reviews
6.8Entertainment
7.4Boarding
7.2Comfort
7.9Crew
6.4Food
Airline reviews
As with most flights these days it was delayed by about 30 min.
6.0 GoodJohn, Sep 2026
As with most flights these days it was delayed by about 30 min.
Flight was 3 hours delayed. They gave our plan to two other routes. Need to knock that off.
We called Kayak for a change due to the TSA situation in Atlanta. What we got was a canceled return flight (in error) and we had to find the mistake. Not happy with Kayak who blamed it on AA.
Small plane, poor meal choices for first class, bad terminal and boarding experience at LAX
Boarding delayed 20 minutes for no reason, no wifi, in flight entertainment, or snacks / waters?
This flight captain and crew were amazing, started ahead of time of departure and reached 30 mins before arrival time. Amazing!
Improvements in communication and empathy are absolutely necessary for American Airlines staff (top down). It’s like they are numb to the needs of their customers.
Even though there was space, they made me check out my luggage. It was very annoying. That’s the reason I bring a carry on so that I don’t have to check out my luggage!!!!
I had a TERRIBLE experience with the AA crew. I believe it was disability-related. It’s unlikely I will fly AA again.
Pilots were very conscious about giving us a smooth flight
More options for your flight from Santo Domingo to Missouri
Complete your trip to Missouri with a hotel stay or car rental
Information on your arrival and departure airports
Cabin class types available on flights to Missouri
Cabin classes available on flights to Missouri. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.
Flights from other airports in Santo Domingo to Missouri
Flights from all airports in Santo Domingo to Missouri. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.
Flights to other popular destinations
The most popular flights on KAYAK according to clicks in the last 2 weeks. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.