$261 Find Cheap Flights from Santo Domingo to Missouri - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to Missouri departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Flight Deals
Booking Insights
Flight Deals

Book Cheap Santo Domingo to Missouri Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to Missouri that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to Missouri

Tue, Aug 18 - Tue, Aug 25
Delta Logo
2:53 pm - 11:58 pm
SDQ
-
MCI
10h 05m
1 stop
Delta Logo
10:31 am - 12:54 am
MCI
-
SDQ
13h 23m
2 stops
$651Delta
Tue, Aug 18 - Tue, Aug 25
American Airlines Logo
10:27 am - 10:45 pm
SDQ
-
MCI
13h 18m
1 stop
American Airlines Logo
7:04 am - 6:44 pm
MCI
-
SDQ
10h 40m
1 stop
$681American Airlines
Tue, Aug 18 - Tue, Aug 25
American Airlines Logo
10:27 am - 10:45 pm
SDQ
-
MCI
13h 18m
1 stop
American Airlines Logo
7:04 am - 6:44 pm
MCI
-
SDQ
10h 40m
1 stop
$684American Airlines
Tue, Aug 18 - Tue, Aug 25
American Airlines Logo
10:27 am - 11:37 pm
SDQ
-
MCI
14h 10m
2 stops
American Airlines Logo
5:30 am - 6:44 pm
MCI
-
SDQ
12h 14m
2 stops
$685American Airlines
Tue, Aug 18 - Tue, Aug 25
American Airlines Logo
10:27 am - 11:37 pm
SDQ
-
MCI
14h 10m
2 stops
American Airlines Logo
5:30 am - 6:44 pm
MCI
-
SDQ
12h 14m
2 stops
$687American Airlines
Tue, Aug 18 - Tue, Aug 25
American Airlines Logo
10:27 am - 11:37 pm
SDQ
-
MCI
14h 10m
2 stops
American Airlines Logo
5:30 am - 6:44 pm
MCI
-
SDQ
12h 14m
2 stops
$688American Airlines
Wed, Aug 5 - Tue, Aug 11
American Airlines Logo
4:24 pm - 8:40 am
SDQ
-
MCI
17h 16m
2 stops
American Airlines Logo
5:30 am - 6:44 pm
MCI
-
SDQ
12h 14m
2 stops
$735American Airlines
Wed, Oct 21 - Sat, Oct 24
United Airlines Logo
1:10 pm - 11:59 pm
SDQ
-
MCI
11h 49m
1 stop
United Airlines Logo
6:00 am - 10:46 pm
MCI
-
SDQ
15h 46m
1 stop
$776United Airlines
Wed, Oct 21 - Sat, Oct 24
United Airlines Logo
1:10 pm - 11:59 pm
SDQ
-
MCI
11h 49m
1 stop
United Airlines Logo
7:30 am - 10:46 pm
MCI
-
SDQ
14h 16m
2 stops
$781United Airlines
Wed, Aug 5 - Tue, Aug 11
Delta Logo
6:05 am - 6:33 pm
SDQ
-
MCI
13h 28m
1 stop
Delta Logo
5:43 am - 1:28 pm
MCI
-
SDQ
6h 45m
1 stop
$805Delta
Booking Insights

KAYAK's insights & trends for Santo Domingo to Missouri flights

Get data-powered insights and trends into flights from Santo Domingo to Missouri to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Santo Domingo to Missouri?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santo Domingo to Missouri, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santo Domingo to Missouri is March, when tickets cost $189 (return) on average. On the other hand, the most expensive months are August and July, when the average cost of round-trip tickets is $884 and $697 respectively.

Find deals

Good to know

Low seasonAugust
Cheapest flight$261
Best time to beat the crowds but there is an average 34% increase in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Santo Domingo to Kansas City

FAQs - booking Missouri flights

  • How does KAYAK find such low prices on flights from Santo Domingo to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Santo Domingo to Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Santo Domingo to Missouri with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Santo Domingo to Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Santo Domingo to Missouri

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to Missouri. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11766 reviews
7.9Crew
6.8Entertainment
7.2Comfort
7.5Boarding
6.4Food
Airline reviews

Flight was 3 hours delayed. They gave our plan to two other routes. Need to knock that off.

2.0 MediocreAndrew, Apr 2026
PHL - MCI
Read more American Airlines reviews

Flight was 3 hours delayed. They gave our plan to two other routes. Need to knock that off.

We called Kayak for a change due to the TSA situation in Atlanta. What we got was a canceled return flight (in error) and we had to find the mistake. Not happy with Kayak who blamed it on AA.

Small plane, poor meal choices for first class, bad terminal and boarding experience at LAX

Boarding delayed 20 minutes for no reason, no wifi, in flight entertainment, or snacks / waters?

This flight captain and crew were amazing, started ahead of time of departure and reached 30 mins before arrival time. Amazing!

Improvements in communication and empathy are absolutely necessary for American Airlines staff (top down). It’s like they are numb to the needs of their customers.

Even though there was space, they made me check out my luggage. It was very annoying. That’s the reason I bring a carry on so that I don’t have to check out my luggage!!!!

I had a TERRIBLE experience with the AA crew. I believe it was disability-related. It’s unlikely I will fly AA again.

Pilots were very conscious about giving us a smooth flight

I like the speed of boarding and deplaning and the fact that everything was on time. The crew (attendants) were probably quite new and did not begin the in cabin service until 30 min before landing even though there was little to no air turbulence for the last 1.5 hours of the flight. It made for a mad scramble at the end to get trash collected and carts stowed before touch down.

Everything you need to know for your flight from Santo Domingo to Missouri

Information on your arrival and departure airports

Santo Domingo (SDQ)