SDQ - SFO

$343 Find Cheap Flights from Santo Domingo to San Francisco - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to San Francisco departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to San Francisco, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 21% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$580
Typical prices: $691-$520
Copa Airlines
Tue 10/20Mon 10/26
SDQ - SFO • 1 stop
Cheapest one-way
$343
Typical prices: $245-$351
JetBlue
Fri 10/23
SDQ - SFO • 1 stop
Top airlines
Copa Airlines
Cheapest • from $580 (round-trip)
JetBlue
Best reviews • 7.1 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Santo Domingo and San Francisco. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
New York (JFK)
Cheapest • Avg $572 (round-trip)
Miami (MIA)
Shortest trip • 11h 41m (one-way)
Insights
Insights
Insights
Insights
When to travel
October
Cheapest • 19% price drop
October
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santo Domingo to San Francisco (SDQ-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to San Francisco

Tue, Oct 20 - Mon, Oct 26
Copa Airlines Logo
12:42 pm - 11:40 pm
SDQ
-
SFO
13h 58m
1 stop
Copa Airlines Logo
1:31 am - 10:56 pm
SFO
-
SDQ
18h 25m
1 stop
$580Copa Airlines
Thu, Aug 13 - Tue, Aug 18
JetBlue Logo
4:44 pm - 11:50 pm
SDQ
-
SFO
10h 06m
1 stop
JetBlue Logo
10:57 am - 11:59 pm
SFO
-
SDQ
10h 02m
1 stop
$611JetBlue
Thu, Sep 24 - Fri, Oct 2
Copa Airlines Logo
2:16 pm - 11:40 pm
SDQ
-
SFO
12h 24m
1 stop
Copa Airlines Logo
1:12 am - 2:25 am
SFO
-
SDQ
22h 13m
1 stop
$651Copa Airlines
Fri, Aug 14 - Wed, Aug 19
JetBlue Logo
1:34 pm - 11:50 pm
SDQ
-
SFO
13h 16m
1 stop
JetBlue Logo
10:57 am - 3:21 pm
SFO
-
SDQ
25h 24m
1 stop
$654JetBlue
Thu, Oct 29 - Tue, Nov 10
JetBlue Logo
1:28 pm - 11:30 pm
SDQ
-
SFO
13h 02m
1 stop
JetBlue Logo
8:55 pm - 2:10 pm
SFO
-
SDQ
13h 15m
1 stop
$666JetBlue
Tue, Oct 20 - Tue, Oct 27
Multiple Airlines Logo
3:35 pm - 4:57 pm
SDQ
-
SFO
28h 22m
2 stops
Multiple Airlines Logo
1:35 pm - 7:18 am
SFO
-
SDQ
14h 43m
1 stop
$681Multiple Airlines
Thu, Aug 27 - Mon, Aug 31
JetBlue Logo
4:44 pm - 11:50 pm
SDQ
-
SFO
10h 06m
1 stop
JetBlue Logo
10:40 pm - 12:24 pm
SFO
-
SDQ
10h 44m
1 stop
$686JetBlue
Thu, Oct 29 - Tue, Nov 10
JetBlue Logo
1:28 pm - 11:30 pm
SDQ
-
SFO
13h 02m
1 stop
JetBlue Logo
8:55 pm - 2:10 pm
SFO
-
SDQ
13h 15m
1 stop
$716JetBlue
Thu, Jul 9 - Mon, Aug 3
Copa Airlines Logo
2:17 pm - 11:40 pm
SDQ
-
SFO
12h 23m
1 stop
Copa Airlines Logo
1:12 am - 10:56 pm
SFO
-
SDQ
18h 44m
1 stop
$726Copa Airlines
Thu, Jul 23 - Wed, Jul 29
JetBlue Logo
5:01 am - 11:51 pm
SDQ
-
SFO
21h 50m
1 stop
JetBlue Logo
10:40 pm - 11:59 pm
SFO
-
SDQ
22h 19m
1 stop
$729JetBlue
Booking Insights

KAYAK's insights & trends for Santo Domingo to San Francisco flights

Get data-powered insights and trends into flights from Santo Domingo to San Francisco to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santo Domingo to San Francisco?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santo Domingo to San Francisco departing in October.

What is the cheapest month to fly from Santo Domingo to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santo Domingo to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santo Domingo to San Francisco is October, where tickets cost $544 (return) on average. On the other hand, the most expensive months are June and July, where the average cost of round-trip tickets is $1,055 and $789 respectively.

Find deals

Good to know

Low seasonJuly
Cheapest flight$343
Best time to beat the crowds but there is an average 17% increase in price.
Most popular time to fly and prices are also 20% lower on average.
Flight from Santo Domingo to San Francisco

When to book flights from Santo Domingo to San Francisco

Are your dates flexible? Find out the best times to travel from Santo Domingo to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santo Domingo to San Francisco

  • What is the cheapest flight from Santo Domingo to San Francisco?

    In the last 5 days, the lowest price for a flight from Santo Domingo to San Francisco was $343 for a one-way ticket and $580 for a round-trip.

  • Do I need a passport to fly between Santo Domingo and San Francisco?

    Yes

  • Which aircraft models fly most regularly from Santo Domingo to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • How does KAYAK find such low prices on flights from Santo Domingo to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Santo Domingo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Santo Domingo with another airline. Booking your flights between Santo Domingo and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Santo Domingo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Santo Domingo to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
JetBlueOverall score based on 2981 reviews
7.2Entertainment
7.3Boarding
7.9Crew
6.6Food
7.5Comfort
Airline reviews

It was inexplicably canceled and we are stuck in LA, haven't gotten home and it has been an inconvenience having lost work (on unpaid leave for my husband).

2.0 MediocreAnonymous, Jun 2026
LAX - FLL
Read more JetBlue reviews

It was inexplicably canceled and we are stuck in LA, haven't gotten home and it has been an inconvenience having lost work (on unpaid leave for my husband).

JetBlue worker, Blythe, was so amazing at the DCA counter. If it wasn’t for her, I’m not sure we would’ve made it through. Please thank her!

They lost my luggage and refuse to help. Terrible airline. I've never experienced worse customer service in my life. Pretty much just told me too bad that I lost all my luggage, not caring that I am stuck in Europe for 2 weeks with absolutely nothing.

You should have had Wifi to make it much enjoyable.

The flight out was delayed from 3:40pm to 5pm and again to 8pm. We boarded after 5pm, had to disembark because they could not get the Engine started, then we switched gates and got a new plane and did not board until after 8pm.

The flight was delayed after already taxiing from the gate due to a malfunction. After 3 hours we were told the flight was canceled. The next flight available was Sunday. My daughter and I stayed overnight in the airport due to this issue. I was given a $12 meal voucher. Unacceptable

Whole experience was poor. Delayed 2 hours. Lied about the delays. Was all jet blues fault and tried to blame on air traffic control. Sent out other let trips and wouldn't allow people to switch aircraft.

My bag was not loaded on my flight. it was not communicated to me until i was waiting for my bag at my destination. there was no confirmation of when my bag was arriving and no way to track it.

Nice plane, clean, wifi available and movies. All the flight attendants were courteous.

The gate attendant in Boston had a high raspy voice and spoke much too fast to be understood. Not pleasant.

Everything you need to know for your flight from Santo Domingo to San Francisco

Information on your arrival and departure airports

Santo Domingo (SDQ)
San Francisco (SFO)