SDQ - SFO

$278 Find Cheap Flights from Santo Domingo to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to San Francisco departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to San Francisco, as well as popular online travel agencies
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Flights Deals

Cheap Flights from Santo Domingo to San Francisco (SDQ-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to San Francisco

Thu, Jul 10 - Mon, Jul 14
Frontier Logo
11:50 am - 10:25 amSDQ-SFO
25h 35m1 stop
Frontier Logo
10:29 pm - 12:28 amSFO-SDQ
22h 59m1 stop
$388Frontier
Find Deal
Thu, Jul 10 - Mon, Jul 14
Frontier Logo
11:50 am - 10:25 amSDQ-SFO
25h 35m1 stop
Frontier Logo
10:29 pm - 12:28 amSFO-SDQ
22h 59m1 stop
$397Frontier
Find Deal
Tue, Oct 21 - Sat, Oct 25
JetBlue Logo
12:47 pm - 12:59 amSDQ-SFO
15h 12m1 stop
JetBlue Logo
10:15 pm - 2:50 pmSFO-SDQ
13h 35m1 stop
$533JetBlue
Find Deal
Tue, Aug 12 - Fri, Aug 15
Avianca Logo
11:45 am - 11:55 pmSDQ-SFO
15h 10m2 stops
Avianca Logo
2:20 pm - 10:50 amSFO-SDQ
17h 30m2 stops
$542Avianca
Find Deal
Thu, Aug 14 - Sun, Aug 17
Avianca Logo
11:45 am - 11:55 pmSDQ-SFO
15h 10m2 stops
Avianca Logo
2:20 pm - 10:50 amSFO-SDQ
17h 30m2 stops
$543Avianca
Find Deal
Sat, Aug 16 - Fri, Aug 22
Avianca Logo
11:45 am - 11:55 pmSDQ-SFO
15h 10m2 stops
Avianca Logo
2:20 pm - 10:50 amSFO-SDQ
17h 30m2 stops
$552Avianca
Find Deal
Sat, Aug 2 - Sat, Aug 9
JetBlue Logo
2:32 pm - 11:49 pmSDQ-SFO
12h 17m1 stop
JetBlue Logo
11:30 am - 1:15 amSFO-SDQ
10h 45m1 stop
$620JetBlue
Find Deal
Thu, Aug 14 - Sat, Aug 16
American Airlines Logo
10:25 am - 10:59 pmSDQ-SFO
15h 34m1 stop
American Airlines Logo
12:45 am - 3:25 pmSFO-SDQ
11h 40m2 stops
$720American Airlines
Find Deal
Sat, Aug 16 - Thu, Aug 21
American Airlines Logo
7:20 pm - 11:15 amSDQ-SFO
18h 55m1 stop
American Airlines Logo
12:45 am - 6:20 pmSFO-SDQ
14h 35m2 stops
$733American Airlines
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Thu, Nov 20 - Wed, Nov 26
Delta Logo
4:22 pm - 10:52 pmSDQ-SFO
10h 30m1 stop
Delta Logo
9:30 pm - 6:39 pmSFO-SDQ
17h 09m2 stops
$4,109Delta
Find Deal
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KAYAK's insights & trends for Santo Domingo to San Francisco flights

Get data-powered insights and trends into flights from Santo Domingo to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Santo Domingo to San Francisco?

The average price of all round-trip flights from Santo Domingo to San Francisco clicked on KAYAK for each day over the last 12 months.

For Santo Domingo to San Francisco, Thursday is the cheapest day to fly on average and Friday is the most expensive. Flying from San Francisco back to Santo Domingo, the best deals are generally found on Tuesday, with Saturday being the most expensive.

What is the cheapest month to fly from Santo Domingo to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santo Domingo to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santo Domingo to San Francisco is September, where tickets cost $537 (return) on average. On the other hand, the most expensive months are June and February, where the average cost of round-trip tickets is $1,001 and $793 respectively.

How far in advance should I book a flight from Santo Domingo to San Francisco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santo Domingo to San Francisco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santo Domingo to San Francisco, you should book around 5 weeks before departure. For the absolute cheapest price, our data suggests you should book 25 weeks before departure.

Good to know

Low seasonJanuary
High seasonDecember
Cheapest flight$278
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly and prices are also 19% lower on average.
Flight from Santo Domingo to San Francisco

When to book flights from Santo Domingo to San Francisco

Are your dates flexible? Find out the best times to travel from Santo Domingo to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santo Domingo to San Francisco

  • What is the cheapest flight from Santo Domingo to San Francisco?

    In the last 3 days, the lowest price for a flight from Santo Domingo to San Francisco was $278 for a one-way ticket and $388 for a round-trip.

  • Do I need a passport to fly between Santo Domingo and San Francisco?

    Yes

  • Which aircraft models fly most regularly from Santo Domingo to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santo Domingo to San Francisco?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between Santo Domingo and San Francisco, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Santo Domingo to San Francisco, Delta or JetBlue?

    The two airlines most popular with KAYAK users for flights from Santo Domingo to San Francisco are Delta and JetBlue. With an average price for the route of $678 and an overall rating of 8.0, Delta is the most popular choice. JetBlue is also a great choice for the route, with an average price of $642 and an overall rating of 7.3.

  • How does KAYAK find such low prices on flights from Santo Domingo to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Santo Domingo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Santo Domingo with another airline. Booking your flights between Santo Domingo and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Santo Domingo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Santo Domingo to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7964 reviews
7.9Entertainment
7.9Comfort
7.3Food
8.2Boarding
8.5Crew
Airline reviews

5 hours of delay that could've been much shorter if Delta had taken the 1 hour delay they imposed on the flight before boarding to run any of the plane checks required for flight to find the hydraulic issue that required nearly 3 hours to fix. $24 of meal credit buys a sandwich and a soft drink. Poor communication within the terminal about what gate we'd be re-boarding from and when we'd be re-boarding.

2.0 MediocreAnonymous, Jun 2025BOS - LAX
Read more Delta reviews

5 hours of delay that could've been much shorter if Delta had taken the 1 hour delay they imposed on the flight before boarding to run any of the plane checks required for flight to find the hydraulic issue that required nearly 3 hours to fix. $24 of meal credit buys a sandwich and a soft drink. Poor communication within the terminal about what gate we'd be re-boarding from and when we'd be re-boarding.

The entertainment and wifi mostly didn't work on this flight.

Terrible entertainment system - kept freezing and audio kept cutting out. Snacks were mediocre at best for a 5 hour flight.

I am still upset that my bag was lost on a recent trip to Rome ; we were inconvenienced and out €150 Euros ; delta has refused to reimburse us

Subject: Complaint Regarding Disrespectful Behavior by Delta Air Lines Staff at Boarding Gate Dear Delta Air Lines Team, I am writing to formally file a complaint regarding the behavior of a staff member at the boarding gate today, May 14, 2025, at Las Américas International Airport. While we were preparing to board flight DL-1829 to New York, scheduled for 2:28 PM at gate T-11, we were informed that the aircraft was experiencing water system issues and that passengers were advised to use the restroom before boarding. I politely approached one of the Delta staff members to ask whether the lavatory would be partially or completely unavailable during the flight, as I am traveling with a baby in my arms. The employee’s response was extremely rude and arrogant. He replied, in an unnecessarily hostile tone, something along the lines of: “It’s either that or we cancel the flight — do you want us to cancel the flight?” This response lacked any empathy or professionalism. I understand that technical issues can arise, but that does not excuse such inappropriate treatment of passengers. I felt deeply disrespected and disappointed by the interaction. I sincerely hope appropriate measures are taken, and that all staff members receive the necessary training to treat passengers with courtesy, especially in delicate situations like this one.

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

I love the free WiFi!! Crew was nice. Bathroom was decent. First time flying delta in a long time and I enjoyed it. Will definitely look into booking with Delta more but I think Delta is a little more expensive than the other airlines.

Seats are much much more comfortable than United, which is what I usually fly

Everything was ok!! Just bags came up a little be late.

It was terrible, I sat next to a person with a cat, I'm allergic to animal dander, my discomfort was extreme

The check in and boarding process was a bit of a cluster. Two people at the counter to check in, three random lines that nobody knew which was for what, and people kept getting shuffled from one line to another for no apparent reason because then they’d get shuffled back and end up getting out further back in the line than they were originally. I only had to hand my already checked bag over and it took 45 minutes. I was never assigned a seat so when I tried to board I was pulled out of line again while someone had to try to manually assign me a seat. During the flight I got up to go to the bathroom, and there was an attendant in the aisle offering pillows etc and it was a 30 min wait unbuckled standing by the bathrooms because she said I couldn’t go past her. First and last time flying jet blue to be honest.

Communication since no reason or explanation was given for 3 hrs delay

Flight was delayed several 3 hours - no reason was given and no communication what so ever.

No overhead baggage room even though I was seated in row 2. Consequently had to check in my carry on bag. Baggage carousel was jammed. Took 45 min to get my bag.

Excellent. Although they used to greet me as a mosaic member and provide a free drink, early boarding helps me to keep coming back to JetBlue.

Great flight. Departed early, arrived early. However they were out of meals for sale. Also, we arrived early and the gate was not available so we sat on the taxiway for quite a while (not JetBlue’s fault).

The gate and ground staff were excellent, friendly, went out of their way to acknowledge my Mosaic status. The plane was an older Airbus, so the seats were a little worn. The in flight attendant was not very nice, and seemed to be annoyed to be at work or be on this flight. Flight was fast and we landed early and pilots kept us informed.

Cancelled flight with no specific instructions to get a boarding pass for another flight. The whole flight of people were in line for an hour because there was only 1 person to help at the desk. This was unusual for JetBlue.

The inflight system with their wifi is a hot mess and doesn't work. Separately they do, but when you try to do theoretically simple things like pair a device for control it all falls apart

It was too hot in the cabin. The AC did not help.

Loved the staff, boarding and drink options! Wish the comfort of the seat could have been better nevertheless

Honestly, I haven’t flown American in years, probably due to the pandemic and my being unable to travel for certain periods in the last two years, but it was a good experience to dig out or obtain a new American Airlines account after many years of traveling for business with American in the past.

Long 5 hour and 45 min flight and only one drink service and cookie snack

One bottle of water and a package of cookies for comfort plus. We had to literally beg a flight attendant for an extra bottle of water later in the flight due to feeling dehydrated.

Flight boarded from Gate 39 at OGG, the farthest gate in the terminal. There were no Hawaiian themed amenities for the flight. The first class service was mediocre at best; I received not special welcome or recognition as an executive platinum member of American Advantage program. The flight attendants were more concerned with their cell phones than saying "thank you" to the passengers as we disembarked. Fortunately, the flight arrived at LAX a few minutes early.

Bigger seats. Board back to front! Disembark front to back!

Extraordinary service in business class, and very good breakfast and snacks. A really lovely flight.

This flight didn’t happen because AA agents didn’t let us board the flight

Plane was pretty clean, staff was friendly and helpful, flight left about on time arrived early. Took a long time to board and get off the plane - carry on items didn't have enough room so people had to move all around to find places.

The service and food needs to improve to catch up with other international flights

Everything you need to know for your flight from Santo Domingo to San Francisco

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