SDQ - SFO

$246 Find Cheap Flights from Santo Domingo to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to San Francisco departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to San Francisco, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Santo Domingo to San Francisco (SDQ-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to San Francisco

Tue, Oct 21 - Fri, Oct 31
JetBlue Logo
12:47 pm - 12:59 amSDQ-SFO
15h 12m1 stop
JetBlue Logo
8:00 am - 9:32 amSFO-SDQ
22h 32m1 stop
$472JetBlue
Find Deal
Tue, Oct 21 - Sat, Oct 25
JetBlue Logo
3:00 pm - 12:59 amSDQ-SFO
12h 59m1 stop
JetBlue Logo
11:20 pm - 1:17 pmSFO-SDQ
10h 57m1 stop
$491JetBlue
Find Deal
Tue, Oct 14 - Tue, Oct 21
JetBlue Logo
2:54 pm - 11:16 pmSDQ-SFO
11h 22m1 stop
JetBlue Logo
11:20 pm - 1:43 pmSFO-SDQ
11h 23m1 stop
$506JetBlue
Find Deal
Tue, Oct 21 - Fri, Oct 31
Multiple Airlines Logo
2:10 pm - 11:39 pmSDQ-SFO
12h 29m1 stop
Multiple Airlines Logo
5:53 pm - 2:54 pmSFO-SDQ
18h 01m2 stops
$509Multiple Airlines
Find Deal
Tue, Oct 14 - Tue, Oct 21
JetBlue Logo
2:54 pm - 11:16 pmSDQ-SFO
11h 22m1 stop
JetBlue Logo
11:20 pm - 1:43 pmSFO-SDQ
11h 23m1 stop
$518JetBlue
Find Deal
Tue, Oct 21 - Fri, Oct 31
Multiple Airlines Logo
2:10 pm - 11:39 pmSDQ-SFO
12h 29m1 stop
Multiple Airlines Logo
5:53 pm - 9:45 pmSFO-SDQ
24h 52m2 stops
$521Multiple Airlines
Find Deal
Mon, Oct 13 - Mon, Oct 20
Avianca Logo
11:45 am - 12:35 pmSDQ-SFO
27h 50m2 stops
Avianca Logo
2:20 pm - 5:15 pmSFO-SDQ
23h 55m2 stops
$525Avianca
Find Deal
Tue, Oct 14 - Tue, Oct 21
Multiple Airlines Logo
2:10 pm - 11:39 pmSDQ-SFO
12h 29m1 stop
Multiple Airlines Logo
2:20 pm - 5:15 pmSFO-SDQ
23h 55m2 stops
$530Multiple Airlines
Find Deal
Fri, Oct 31 - Thu, Nov 6
Avianca Logo
5:45 pm - 1:00 pmSDQ-SFO
22h 15m2 stops
Avianca Logo
1:35 am - 4:50 pmSFO-SDQ
35h 15m2 stops
$533Avianca
Find Deal
Tue, Oct 21 - Thu, Oct 30
Avianca Logo
6:10 pm - 12:35 pmSDQ-SFO
21h 25m2 stops
Avianca Logo
2:35 am - 4:50 pmSFO-SDQ
35h 15m2 stops
$534Avianca
Find Deal

Everything you should know

Top airlines
JetBlue
Cheapest • from $472 (round-trip)
American Airlines
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
September
Cheapest • 19% price drop
September
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$472
Overall average: $691
JetBlue
Tue 10/21Fri 10/31
SDQ - SFO • 1 stop
Cheapest one-way
$246
Typical prices: $329-419
JetBlue
Wed 10/15
SDQ - SFO • 1 stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Booking Insights

KAYAK's insights & trends for Santo Domingo to San Francisco flights

Get data-powered insights and trends into flights from Santo Domingo to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Santo Domingo to San Francisco?

The average price of all round-trip flights from Santo Domingo to San Francisco clicked on KAYAK for each day over the last 12 months.

For Santo Domingo to San Francisco, Thursday is the cheapest day to fly on average and Friday is the most expensive. Flying from San Francisco back to Santo Domingo, the best deals are generally found on Tuesday, with Saturday being the most expensive.

What is the cheapest month to fly from Santo Domingo to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santo Domingo to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santo Domingo to San Francisco is September, where tickets cost $537 (return) on average. On the other hand, the most expensive months are February and August, where the average cost of round-trip tickets is $793 and $754 respectively.

Good to know

Low seasonJune
Cheapest flight$246
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly and prices are also 19% lower on average.
Flight from Santo Domingo to San Francisco

When to book flights from Santo Domingo to San Francisco

Are your dates flexible? Find out the best times to travel from Santo Domingo to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santo Domingo to San Francisco

  • What is the cheapest flight from Santo Domingo to San Francisco?

    In the last 3 days, the lowest price for a flight from Santo Domingo to San Francisco was $246 for a one-way ticket and $472 for a round-trip.

  • Do I need a passport to fly between Santo Domingo and San Francisco?

    Yes

  • Which aircraft models fly most regularly from Santo Domingo to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santo Domingo to San Francisco?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between Santo Domingo and San Francisco, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Santo Domingo to San Francisco, JetBlue or American Airlines?

    The two airlines most popular with KAYAK users for flights from Santo Domingo to San Francisco are JetBlue and American Airlines. With an average price for the route of $630 and an overall rating of 7.2, JetBlue is the most popular choice. American Airlines is also a great choice for the route, with an average price of $790 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Santo Domingo to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Santo Domingo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Santo Domingo with another airline. Booking your flights between Santo Domingo and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Santo Domingo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Santo Domingo to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
6.4Food
7.2Comfort
6.9Entertainment
7.5Boarding
8.0Crew
Airline reviews

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

10.0 ExcellentEnchantress, Sep 2025JFK - SFO
Read more American Airlines reviews

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Did not get the seat I selected and paid for.

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

Delayed flight that lead to a missed connection and a 5-hour trip became a 12-hour flight 🙄

There is no room, no gluten free options, or any free internet/entertainment. You have to bring your own tablet or smartphone because there are no screens.

American Airlines is a mediocre airlines: they do not maintain the highest standard of cleanliness in the cabins, and the food is not well thought out. Service is not at top of mind compared to other international airlines such as Singapore Airlines, JAL or others.

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

Boarding gate in Honolulu was staffed with a great clerk with a soothing voice despite the flight delay of over an hour. Flight attendants in the plane were all grumpy, not pleasant looking bunch. Their sour attitude showed throughout the flight. Inly able to get a select few movies started. Most of the movie links in the “free entertainment” did not work.

I flew Business Class. Rory, one of the Cabin stewards, was attentive, explained the menu, provided appropriate drinks. was

They have the most inexperienced / rude flight staff I’ve encountered

very difficult boarding process - aggressive passengers not the friendliest crew

WiFi was not eorkig (again) And the plane was from 1990 with the screens which were.not touch and most didn’t even work and if lucky could tune in tv

I paid extra for a seat closer to the front. The TV didn’t work at all for the entire flight. Would have been nice to know before I purchased an “upgraded “ seat

It was great. I had never flown on JetBlue before, but would be very happy to fly with them in the future.

Worst flight experience ever flights canceled. JetBlue told us just did not even bother standing in line to come back in one and a half hours then without any information we had to go pick up all of our luggage and spend over $2000 in accommodation just to get home. JetBlue said that the next flight available for us to get home would be three days later. Absolutely absurd hasn’t offered to give us any compensation do not fly JetBlue horrible company. They said it was based on the weather and the weather is great in all locations that we would’ve been flying to total hoax. I think it’s a conspiracy theory.

The captain gave good announcements and the flight attendants were friendly. The WiFi was pretty good. The plane itself looked very old inside and the seats were very uncomfortable. The screens in the seat backs were the smallest I’ve ever seen. There were so many loud and obnoxious kids on this flight and the parents didn’t do much to try to quiet them down. Some had videos and games on tablets with higher than necessary volume going the whole time.

Too many long delays with JetBlue. Worst major airline that serves JFK but unfortunately I keep going back because of the prices.

My JetBlue experience was nice. The flights ran on time, the aircraft was clean and comfortable, and the flight attendants were attentive. My only issue, which is isolated to the low-cost (budget) option at JetBlue, is that the check in process makes the user feel that they have to buy their seats. The seats offered for purchase are upgrades from the budget seats you get (which are essentially the last seats remaining). The interface should not make it feel like you must purchase a seat.

The plane was late to leave.. Internet was lousy. TV was not working. when we arrived, We stayed on the plane for a long time before we got to the gate. It took us a long time to retrieve our luggage because they didn’t know what carousel to send them to. It was a bad experience.

Everything you need to know for your flight from Santo Domingo to San Francisco

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