SDQ - SFO

$216 Find Cheap Flights from Santo Domingo to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to San Francisco departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to San Francisco, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$599
Overall average: $630
Multiple Airlines
Tue 11/18Mon 12/15
SDQ - SFO • 2 stops
Cheapest one-way
$216
Typical prices: $339-$429
Multiple Airlines
Fri 11/14
SDQ - SFO • 3 stops
Top airlines
JetBlue
Cheapest • from $644 (round-trip)
American Airlines
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
September
Cheapest • 17% price drop
October
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santo Domingo to San Francisco (SDQ-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to San Francisco

Tue, Nov 18 - Mon, Dec 15
Multiple Airlines Logo
6:10 am - 1:50 pmSDQ-SFO
35h 40m2 stops
Multiple Airlines Logo
9:59 pm - 5:25 amSFO-SDQ
27h 26m1 stop
$599Multiple Airlines
Find Deal
Fri, Dec 5 - Thu, Dec 11
Multiple Airlines Logo
6:10 am - 4:50 pmSDQ-SFO
14h 40m1 stop
Multiple Airlines Logo
7:00 am - 12:45 amSFO-SDQ
13h 45m1 stop
$614Multiple Airlines
Find Deal
Tue, Nov 18 - Mon, Dec 15
Multiple Airlines Logo
6:10 am - 9:34 pmSDQ-SFO
19h 24m1 stop
Multiple Airlines Logo
9:59 pm - 5:25 amSFO-SDQ
27h 26m1 stop
$616Multiple Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
JetBlue Logo
4:10 am - 4:37 pmSDQ-SFO
16h 27m1 stop
JetBlue Logo
9:44 pm - 8:51 pmSFO-SDQ
19h 07m2 stops
$644JetBlue
Find Deal
Fri, Feb 20 - Mon, Feb 23
JetBlue Logo
8:01 am - 11:46 pmSDQ-SFO
19h 45m1 stop
JetBlue Logo
12:55 pm - 10:03 amSFO-SDQ
17h 08m1 stop
$684JetBlue
Find Deal
Fri, Dec 5 - Thu, Dec 11
American Airlines Logo
6:23 pm - 9:42 amSDQ-SFO
19h 19m2 stops
American Airlines Logo
6:15 pm - 12:28 pmSFO-SDQ
14h 13m2 stops
$698American Airlines
Find Deal
Wed, Dec 17 - Sun, Jan 4
American Airlines Logo
6:00 am - 8:56 pmSDQ-SFO
18h 56m2 stops
American Airlines Logo
10:39 pm - 11:59 pmSFO-SDQ
21h 20m1 stop
$740American Airlines
Find Deal
Fri, Feb 20 - Mon, Feb 23
Delta Logo
7:05 am - 9:02 pmSDQ-SFO
17h 57m1 stop
Delta Logo
6:00 am - 11:59 pmSFO-SDQ
13h 59m2 stops
$751Delta
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Fri, Feb 20 - Sun, Feb 22
Copa Airlines Logo
2:11 pm - 11:20 pmSDQ-SFO
13h 09m1 stop
Copa Airlines Logo
12:42 am - 10:39 pmSFO-SDQ
17h 57m1 stop
$876Copa Airlines
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Fri, Feb 20 - Sun, Feb 22
Copa Airlines Logo
2:11 pm - 11:20 pmSDQ-SFO
13h 09m1 stop
Copa Airlines Logo
12:42 am - 4:12 pmSFO-SDQ
11h 30m1 stop
$979Copa Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Santo Domingo to San Francisco flights

Get data-powered insights and trends into flights from Santo Domingo to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Santo Domingo to San Francisco?

The average price of all round-trip flights from Santo Domingo to San Francisco clicked on KAYAK for each day over the last 12 months.

For Santo Domingo to San Francisco, Thursday is the cheapest day to fly on average and Friday is the most expensive. Flying from San Francisco back to Santo Domingo, the best deals are generally found on Tuesday, with Saturday being the most expensive.

What is the cheapest month to fly from Santo Domingo to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santo Domingo to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santo Domingo to San Francisco is September, where tickets cost $537 (return) on average. On the other hand, the most expensive months are February and August, where the average cost of round-trip tickets is $793 and $754 respectively.

Find deals

Good to know

Low seasonJune
Cheapest flight$216
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly and prices are also 17% lower on average.
Flight from Santo Domingo to San Francisco

When to book flights from Santo Domingo to San Francisco

Are your dates flexible? Find out the best times to travel from Santo Domingo to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santo Domingo to San Francisco

  • What is the cheapest flight from Santo Domingo to San Francisco?

    In the last 3 days, the lowest price for a flight from Santo Domingo to San Francisco was $216 for a one-way ticket and $599 for a round-trip.

  • Do I need a passport to fly between Santo Domingo and San Francisco?

    Yes

  • Which aircraft models fly most regularly from Santo Domingo to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santo Domingo to San Francisco?

    oneworld is the only airline alliance operating flights between Santo Domingo and San Francisco.

  • Which is the best airline for flights from Santo Domingo to San Francisco, JetBlue or American Airlines?

    The two airlines most popular with KAYAK users for flights from Santo Domingo to San Francisco are JetBlue and American Airlines. With an average price for the route of $595 and an overall rating of 7.2, JetBlue is the most popular choice. American Airlines is also a great choice for the route, with an average price of $790 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Santo Domingo to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Santo Domingo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Santo Domingo with another airline. Booking your flights between Santo Domingo and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Santo Domingo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Santo Domingo to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11030 reviews
6.9Entertainment
7.5Boarding
6.4Food
8.0Crew
7.2Comfort
Airline reviews

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

8.0 ExcellentKohMeng, Oct 2025DFW - LAX
Read more American Airlines reviews

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

We are too tired and frustrated to comment politely at this point

The business class seats are dated and uncomfortable. The space is bare minimum and there is absolutely no privacy. For $4K, this is not what I expect.

The flight crew was rude. We were in first class and no one even offered water until an hour after we were in the air. Horrible experience

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Did not get the seat I selected and paid for.

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

Delayed flight that lead to a missed connection and a 5-hour trip became a 12-hour flight 🙄

There is no room, no gluten free options, or any free internet/entertainment. You have to bring your own tablet or smartphone because there are no screens.

The flight was two hours late due to a computer fault and resulting maintenance. Nothing was offered as compensation beyond bottles of water during the time we were deplaned and waiting in the terminal.

Very pleasant flight attendants. Gate crew rather loud chatting with each other.

Four plus hour flight delay in New York caused us to take off after 11:30pm. We didn’t arrive at our hotel until five hours after check in. Started the trip off feeling exhausted.

Friendly crew. Poor food service maybe due to full flight. All in all, you get what you pay for.

Plane was in bad shape. TV’s and WiFi didn’t work. Plane need a refresh. Not enough room for bags.

Everything was great. I liked the text updates so that I never miss a gate change & I have all the latest info.

I don’t usually fly budget airlines or airlines in the United States. It was as good as any other airline. The seats are comfortable and the airline attendants are not rude & surly. Very nice flight (s).

They have the most inexperienced / rude flight staff I’ve encountered

very difficult boarding process - aggressive passengers not the friendliest crew

WiFi was not eorkig (again) And the plane was from 1990 with the screens which were.not touch and most didn’t even work and if lucky could tune in tv

Everything you need to know for your flight from Santo Domingo to San Francisco

Information on your arrival and departure airports

Santo Domingo (SDQ)
San Francisco (SFO)

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