SDQ - SFO

$228 Find Cheap Flights from Santo Domingo to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to San Francisco departing on 2/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to San Francisco, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$412
Overall average: $369
Multiple Airlines
Tue 3/3Tue 3/31
SDQ - SFO • 1 stop
Cheapest one-way
$228
Typical prices: $314-$587
Multiple Airlines
Fri 2/13
SDQ - SFO • 2 stops
Top airlines
JetBlue
Cheapest • from $459 (round-trip)
JetBlue
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
March
Cheapest • 40% price drop
October
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santo Domingo to San Francisco (SDQ-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to San Francisco

Tue, Mar 3 - Tue, Mar 31
Multiple Airlines Logo
6:05 am - 8:29 pm
SDQ
-
SFO
18h 24m
1 stop
Multiple Airlines Logo
10:38 pm - 2:53 pm
SFO
-
SDQ
13h 15m
1 stop
$412Multiple Airlines
Wed, Apr 29 - Sat, May 9
JetBlue Logo
3:20 am - 2:30 pm
SDQ
-
SFO
14h 10m
1 stop
JetBlue Logo
7:00 am - 1:19 am
SFO
-
SDQ
15h 19m
1 stop
$459JetBlue
Fri, Feb 27 - Mon, Mar 2
JetBlue Logo
7:30 am - 7:34 pm
SDQ
-
SFO
16h 04m
1 stop
JetBlue Logo
8:44 pm - 5:14 pm
SFO
-
SDQ
16h 30m
1 stop
$461JetBlue
Tue, Mar 3 - Tue, Mar 31
JetBlue Logo
6:05 am - 8:29 pm
SDQ
-
SFO
18h 24m
1 stop
JetBlue Logo
11:10 am - 9:10 am
SFO
-
SDQ
19h 00m
1 stop
$463JetBlue
Tue, Mar 3 - Tue, Mar 31
Multiple Airlines Logo
1:11 pm - 9:39 pm
SDQ
-
SFO
36h 28m
2 stops
Multiple Airlines Logo
7:50 am - 5:52 pm
SFO
-
SDQ
31h 02m
1 stop
$471Multiple Airlines
Tue, Mar 3 - Tue, Mar 31
Multiple Airlines Logo
1:11 pm - 9:39 pm
SDQ
-
SFO
36h 28m
2 stops
Multiple Airlines Logo
7:50 am - 5:52 pm
SFO
-
SDQ
31h 02m
1 stop
$472Multiple Airlines
Sat, May 2 - Tue, May 5
JetBlue Logo
4:05 am - 2:21 pm
SDQ
-
SFO
13h 16m
1 stop
JetBlue Logo
10:35 am - 1:19 am
SFO
-
SDQ
11h 44m
1 stop
$475JetBlue
Mon, Mar 16 - Mon, Mar 23
JetBlue Logo
6:50 pm - 9:49 am
SDQ
-
SFO
17h 59m
1 stop
JetBlue Logo
8:44 pm - 3:55 pm
SFO
-
SDQ
16h 11m
1 stop
$485JetBlue
Thu, Apr 30 - Mon, May 11
JetBlue Logo
3:20 am - 2:30 pm
SDQ
-
SFO
14h 10m
1 stop
JetBlue Logo
8:00 am - 1:51 pm
SFO
-
SDQ
26h 51m
1 stop
$487JetBlue
Mon, Mar 16 - Mon, Mar 23
Multiple Airlines Logo
6:50 pm - 9:49 am
SDQ
-
SFO
17h 59m
1 stop
Multiple Airlines Logo
2:20 pm - 4:50 pm
SFO
-
SDQ
23h 30m
2 stops
$506Multiple Airlines
Booking Insights

KAYAK's insights & trends for Santo Domingo to San Francisco flights

Get data-powered insights and trends into flights from Santo Domingo to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Santo Domingo to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santo Domingo to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santo Domingo to San Francisco is March, where tickets cost $369 (return) on average. On the other hand, the most expensive months are February and August, where the average cost of round-trip tickets is $777 and $754 respectively.

Find deals

Good to know

Low seasonJune
Cheapest flight$228
Best time to beat the crowds but there is an average 1% increase in price.
Most popular time to fly and prices are also 12% lower on average.
Flight from Santo Domingo to San Francisco

When to book flights from Santo Domingo to San Francisco

Are your dates flexible? Find out the best times to travel from Santo Domingo to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santo Domingo to San Francisco

  • What is the cheapest flight from Santo Domingo to San Francisco?

    In the last 3 days, the lowest price for a flight from Santo Domingo to San Francisco was $228 for a one-way ticket and $412 for a round-trip.

  • Do I need a passport to fly between Santo Domingo and San Francisco?

    Yes

  • Which aircraft models fly most regularly from Santo Domingo to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • How does KAYAK find such low prices on flights from Santo Domingo to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Santo Domingo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Santo Domingo with another airline. Booking your flights between Santo Domingo and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Santo Domingo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Santo Domingo to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
JetBlueOverall score based on 2891 reviews
6.6Food
8.0Crew
7.5Comfort
7.2Entertainment
7.4Boarding
Airline reviews

Friendly crew, efficient boarding and flight arrived early. Couldn’t ask for a better experience

10.0 Excellentpuravi, Feb 2026
PBI - ISP
Read more JetBlue reviews

Friendly crew, efficient boarding and flight arrived early. Couldn’t ask for a better experience

Terrible. They canceled our early morning flight after midnight on the day of and had no available flights to rebook my family on for the next 72 hours. Yet they still had other flights that were not cancelled from JFK so it couldn’t be based on the weather. It felt like they canceled the flight based on it not being profitable enough for them. I am not interested in traveling with the again. The absolute worse customer service and lack of accountability.

Horribly rude check in at airport, worst in 25 years of flying. All over a simple issue they could have googled to resolve.

First time flying with JetBlue and never again. I went to the counter to request meet and assist because I'm 74 and my wife is 79. I walk with a cane and my wife is handicapped and has her own wheel chair. I told the agent that my wife and luggage was at the entrance door. The ticketing agent said to me that they don't offer meet and assist. I need to bring them our luggage and then go back and get my wife in order to get my boarding pass. As I went back to get my luggage a Southwest agent along with a TSA agent recognized the situation and came over and took my wife and luggage to the JetBlue ticketing counter alongside the line and told the JetBlue agent to issue to take our luggage as soon as they could.

Our flight was delayed 5 hours, very disorganized, bad communication, confusion. Only good thing was the crew.

1) No pilot available for 1 hour 2) no room for most passengers careyon in overhead—-> stowed below 3) when we landed we had to wait 45 min. Before docking at gate as gate was not ready

It was good. I prefer JB over other airlines.I just wish we had headphones for the films, but other than that - good.

we were delayed because of some safety check that wasn't done or available

Qatar Airways only had spicy meals on the menu in economy class. You might want to get food in the airport before boarding.

The ride share experience in JFK is terrible. After traveling on a flight, then you need to take a subway to the last stop to get an uber or lyft. Unacceptable. Bad job JetBlue for permitting JFK and Port Authority to do this to your passengers.

Everything you need to know for your flight from Santo Domingo to San Francisco

Information on your arrival and departure airports

Santo Domingo (SDQ)
San Francisco (SFO)