$269 Find Cheap Flights from Sioux Falls to Mississippi - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to Mississippi departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Sioux Falls to Mississippi

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Jackson
Jackson1 stop$329
Gulfport
Gulfport1 stop$339
Memphis
Memphis1 stop$319
Jackson
Jackson1 stop$329
Gulfport
Gulfport1 stop$339
Memphis
Memphis1 stop$319

Book Cheap Sioux Falls to Mississippi Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to Mississippi that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to Mississippi

Fri, Aug 14 - Sun, Aug 23
American Airlines Logo
6:06 pm - 10:59 pm
FSD
-
MOB
4h 53m
1 stop
American Airlines Logo
5:30 am - 12:17 pm
MOB
-
FSD
6h 47m
1 stop
$319American Airlines
Fri, Aug 14 - Thu, Aug 20
American Airlines Logo
6:06 pm - 10:50 pm
FSD
-
MEM
4h 44m
1 stop
American Airlines Logo
5:44 pm - 12:30 am
MEM
-
FSD
6h 46m
1 stop
$319American Airlines
Wed, Nov 11 - Sat, Nov 14
American Airlines Logo
6:00 am - 11:44 am
FSD
-
JAN
5h 44m
1 stop
American Airlines Logo
12:14 pm - 5:26 pm
JAN
-
FSD
5h 12m
1 stop
$329American Airlines
Fri, Aug 14 - Sun, Aug 23
American Airlines Logo
6:06 pm - 10:59 pm
FSD
-
MOB
4h 53m
1 stop
American Airlines Logo
5:30 am - 12:17 pm
MOB
-
FSD
6h 47m
1 stop
$329American Airlines
Wed, Jan 6 - Sun, Jan 10
Delta Logo
5:15 am - 2:07 pm
FSD
-
JAN
8h 52m
2 stops
Delta Logo
2:40 pm - 10:12 pm
JAN
-
FSD
7h 32m
1 stop
$334Delta
Wed, Jan 6 - Sun, Jan 10
Delta Logo
5:15 am - 3:54 pm
FSD
-
JAN
10h 39m
2 stops
Delta Logo
12:10 pm - 10:51 pm
JAN
-
FSD
10h 41m
2 stops
$339Delta
Sat, Aug 22 - Sat, Aug 29
United Airlines Logo
7:47 am - 3:30 pm
FSD
-
BTR
7h 43m
2 stops
United Airlines Logo
2:15 pm - 11:44 pm
BTR
-
FSD
9h 29m
2 stops
$339United Airlines
Thu, Aug 20 - Sun, Aug 23
American Airlines Logo
12:57 pm - 6:01 pm
FSD
-
GPT
5h 04m
1 stop
American Airlines Logo
5:31 am - 12:17 pm
GPT
-
FSD
6h 46m
1 stop
$339American Airlines
Fri, Sep 4 - Sun, Sep 6
United Airlines Logo
6:39 pm - 11:18 pm
FSD
-
MEM
4h 39m
1 stop
United Airlines Logo
11:44 am - 11:22 pm
MEM
-
FSD
11h 38m
2 stops
$347United Airlines
Thu, Aug 20 - Sun, Aug 23
Multiple Airlines Logo
10:00 pm - 4:51 pm
FSD
-
GPT
18h 51m
1 stop
Multiple Airlines Logo
7:25 pm - 8:01 pm
GPT
-
FSD
24h 36m
2 stops
$460Multiple Airlines
Booking Insights

KAYAK's insights & trends for Sioux Falls to Mississippi flights

Get data-powered insights and trends into flights from Sioux Falls to Mississippi to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Sioux Falls to Mississippi?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Sioux Falls to Mississippi were found on American Airlines ($319) and United Airlines ($347).

Good to know

Cheapest flight

$269
Flight from Sioux Falls to Memphis

FAQs - booking Mississippi flights

  • How does KAYAK find such low prices on flights from Sioux Falls to Mississippi?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to Mississippi.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to Mississippi?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to Mississippi is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to Mississippi?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to Mississippi with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to Mississippi?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to Mississippi up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Sioux Falls to Mississippi

 
See real verified KAYAK customer reviews for airlines flying from Sioux Falls to Mississippi. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Sioux Falls to Mississippi? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11837 reviews
7.9Crew
6.8Entertainment
6.4Food
7.5Boarding
7.2Comfort
Airline reviews

Patrons with larger bags were asked to check the bags when boarding. Seems like the most effective, and least costly way, way to successfully use the cramped space.

10.0 ExcellentSergio, Jul 2026
DCA - CLE
Read more American Airlines reviews

Patrons with larger bags were asked to check the bags when boarding. Seems like the most effective, and least costly way, way to successfully use the cramped space.

Like all planes recently, entertainment is achieved by giving the patron free WiFi and letting them stream shows via the screen on a phone or tablet.

Worst communication. Delayed boarding for two hours without a single announcement until hour 1 had passed - on time status showing until our flight was supposed to takeoff and the crew had already walked away. No one was boarding. Disgusting part of DFW overcrowded with no AC on a 97 degree day. Then the first app update is that we’d take off in 15 mins… but again no one had boarded a full flight. No announcement in the terminal so everyone is just crowded around a disgusting place with no info for over an hour which turned into two. This was an overfill flight and a disgrace to passenger decency all while likely just trying to fix their own issue of overbooking. The worst airline at the worst airport.

My seat had a worn out cushion, which made it a bit uncomfortable. Other than that, the flight was excellent.

The flight was delayed almost three hours. I understand delays happen from time to time, but this flight was delayed no less than 10 times. I wish the amount of time of the delay was more accurate, versus delaying in 10 or 20 minute increments many, many times.

I thought American Airlines did well considering the adverse weather situation over July 21 and 22. I especially appreciated the consideration given to me when I got stuck in Miami on my way to Boston from Charleston, West Virginia. Thank you for providing a voucher for an overnight stay. Though it was only a few hours of sleep, it was very helpful. I was able to reschedule my medical appointment and got back to the Boston area on the 1st flight out of Miami as a standby passenger. It was very helpful that I was given number one priority on the standby list.

I had a carry on and a personal bag. I put my personal item under my seat and on way to the seat I put my bag up. I usually close my eyes and rest as I was on call for last 36 hours. I heard very loud announcements that someone needs to identify their bag. Pretty sure it was not mine until the hostess pointed out my jacket details attached to the bag. I asked why she got my bag out. I got berated and did not want to create a scene. But this person needs to be talked to.

American was having a problem with their kiosks when I arrived which made the check-in and bag drop process unusually long. Additionally, they only had one person working check-in. Eventually, the kiosks were fixed and everything else went smoothly.

Other than being delayed 5.5 hours and having to get a hotel because I missed my connecting flight, it was an okay flight. No in-flight Wi-Fi or entertainment.

The flight was short. However, my bag was delayed and was put on another flight.

Everything you need to know for your flight from Sioux Falls to Mississippi

Information on your arrival and departure airports