$269 Find Cheap Flights from South Dakota to Mississippi - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from South Dakota to Mississippi departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

Save 20% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Useful Info

Good to know

Low seasonJanuary
Cheapest flight$269
Best time to beat the crowds but there is an average 3% increase in price.
Most popular time to fly and prices are also 8% lower on average.
Flight from Sioux Falls to Memphis

FAQs for booking flights from South Dakota to Mississippi

  • How does KAYAK find such low prices on flights from South Dakota to Mississippi?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Dakota to Mississippi.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Dakota to Mississippi?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from South Dakota to Mississippi is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South Dakota to Mississippi?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from South Dakota to Mississippi with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Dakota to Mississippi?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from South Dakota to Mississippi up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • How many airports are there in Mississippi?

    There are 8 airports in Mississippi. The busiest airport is Jackson-Evers Intl Airport (JAN), with 55% of all flights arriving there.

  • How long is the flight to Mississippi?

    An average nonstop flight from South Dakota to Mississippi takes 8h 10m, covering a distance of 959 miles. The shortest route is Sioux Falls (FSD) to Jackson (JAN) with an average flight time of 4h 40m.

  • What are the most popular destinations in Mississippi?

    Based on KAYAK flight searches, the most popular destination is Baton Rouge (29% of total searches to Mississippi). The next most popular destinations are Jackson (25%) and Mobile (18%). Searches for flights to Memphis (16%) and to Gulfport (12%) are also popular.

Reviews of the top airline flying from South Dakota to Mississippi

 
Need help choosing which airline to fly with from South Dakota to Mississippi? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11790 reviews
7.9Crew
6.8Entertainment
7.5Boarding
6.4Food
7.2Comfort
Airline reviews

I don’t like the music section but I believe it was a cost decision. I changed my flight last minute due to work issues and had to sit way in the back. The seats were way closer together than I would have preferred.

8.0 ExcellentLisa, Jul 2026
JFK - LAX
Read more American Airlines reviews

I don’t like the music section but I believe it was a cost decision. I changed my flight last minute due to work issues and had to sit way in the back. The seats were way closer together than I would have preferred.

Passenger was too loud for the entire flight crew not once ask them to tame it …. Many passengers are uncomfortable including having headaches

Flight canceled because they didn’t have enough flight attendants. No refunds or credits for future flights

The flight from Milwaukee to Dallas was great the staff absolutely amazing. After that EVERYTHING WENT DOWN HILL!!! ABSOLUTELY HORRIBLE!!! WILL NOT FLY THIS AIRLINE AGAIN

Nothing, I wont be flying American Airlines again and will not be recommending anyone to fly American Airlines. It was the worst experience flying I've ever had.

Boarding was awful - no order, people cutting in line, completely chaotic Planes are very old and uncomfortable. Noticeable difference between Delta and United on same route.

I had a carry on and a personal bag. I put my personal item under my seat and on way to the seat I put my bag up. I usually close my eyes and rest as I was on call for last 36 hours. I heard very loud announcements that someone needs to identify their bag. Pretty sure it was not mine until the hostess pointed out my jacket details attached to the bag. I asked why she got my bag out. I got berated and did not want to create a scene. But this person needs to be talked to.

American was having a problem with their kiosks when I arrived which made the check-in and bag drop process unusually long. Additionally, they only had one person working check-in. Eventually, the kiosks were fixed and everything else went smoothly.

Other than being delayed 5.5 hours and having to get a hotel because I missed my connecting flight, it was an okay flight. No in-flight Wi-Fi or entertainment.

The flight was short. However, my bag was delayed and was put on another flight.

Everything you need to know for your flight to Mississippi

Cabin class types available on flights to South Dakota

Cabin classes available on flights to South Dakota. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.