$170 Find Cheap Flights from South America to Charlotte

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Charlotte departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$253
Overall average: $509
Spirit Airlines
vie. 12/5mié. 1/14
MDE - CLT • 1 stop
Cheapest one-way
$170
Typical prices: $241-$351
Spirit Airlines
lun. 12/15
MDE - CLT • 1 stop
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Flight Deals

Cheap Flights from South America to Charlotte

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from South America to Charlotte that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from South America to Charlotte

vie., dic. 5 - mié., ene. 14
Spirit Airlines Logo
2:05 am - 9:39 amMDE-CLT
7h 34m1 stop
Spirit Airlines Logo
5:06 pm - 12:56 amCLT-MDE
7h 50m1 stop
$253Spirit Airlines
Find Deal
vie., dic. 5 - mar., ene. 6
Spirit Airlines Logo
2:05 am - 9:39 amMDE-CLT
7h 34m1 stop
Spirit Airlines Logo
9:00 am - 1:28 amCLT-MDE
16h 28m1 stop
$254Spirit Airlines
Find Deal
lun., feb. 2 - dom., mar. 8
United Airlines Logo
12:03 pm - 9:59 pmCLO-CLT
33h 56m2 stops
United Airlines Logo
11:27 am - 11:34 pmCLT-CLO
37h 07m2 stops
$547United Airlines
Find Deal
lun., feb. 2 - dom., mar. 8
United Airlines Logo
3:11 pm - 9:16 pmCLO-CLT
30h 05m2 stops
United Airlines Logo
11:27 am - 11:34 pmCLT-CLO
37h 07m2 stops
$548United Airlines
Find Deal
lun., feb. 2 - dom., mar. 8
American Airlines Logo
3:20 pm - 11:57 pmCLO-CLT
8h 37m1 stop
American Airlines Logo
7:30 pm - 12:55 pmCLT-CLO
18h 25m1 stop
$553American Airlines
Find Deal
lun., feb. 2 - dom., mar. 8
American Airlines Logo
3:20 pm - 10:45 amCLO-CLT
19h 25m1 stop
American Airlines Logo
10:25 pm - 12:55 pmCLT-CLO
15h 30m1 stop
$554American Airlines
Find Deal
sáb., dic. 20 - mar., ene. 20
Delta Logo
7:00 pm - 10:53 amUIO-CLT
15h 53m2 stops
Delta Logo
1:13 pm - 9:35 pmCLT-UIO
8h 22m1 stop
$600Delta
Find Deal
lun., feb. 9 - mié., feb. 25
LATAM Airlines Logo
11:45 pm - 8:42 amUIO-CLT
8h 57m1 stop
LATAM Airlines Logo
11:45 am - 5:17 amCLT-UIO
17h 32m2 stops
$601LATAM Airlines
Find Deal
vie., dic. 19 - dom., ene. 11
Delta Logo
7:00 pm - 3:46 pmUIO-CLT
20h 46m2 stops
Delta Logo
2:25 pm - 9:35 pmCLT-UIO
7h 10m1 stop
$612Delta
Find Deal
lun., feb. 9 - mié., feb. 25
LATAM Airlines Logo
7:00 pm - 11:05 amUIO-CLT
40h 05m2 stops
LATAM Airlines Logo
2:20 pm - 5:17 amCLT-UIO
14h 57m2 stops
$650LATAM Airlines
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Useful Info

Good to know

Low seasonOctober
Cheapest flight$170
Best time to beat the crowds but there is an average 8% increase in price.
Most popular time to fly and prices are also 8% lower on average.
Flight from Medellín to Charlotte

FAQs for booking flights from South America to Charlotte

  • How does KAYAK find such low prices on flights from South America to Charlotte?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South America to Charlotte.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South America to Charlotte?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Charlotte from South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South America to Charlotte?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Charlotte with an airline and back to South America with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South America to Charlotte?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Charlotte from South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from South America to Charlotte

 
Need help choosing which airline to fly with from South America to Charlotte? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7995 reviews
7.9Comfort
7.9Entertainment
8.2Boarding
8.5Crew
7.3Food
Airline reviews

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

8.0 ExcellentBobby, Oct 2025GSP - ATL
Read more Delta reviews

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

The customer service before board was very rude and when I expressed my concerns about making the connecting flight she laughed and told me I bought the wrong ticket. I explained once it showed the flight was delayed it no longer let me change seats or anything. I was trying to upgrade to make sure I would get to the next gate on time.

Non stop on long haul is the way to go. Great experience

Seats comfortable, service and food very mediocre, staff not very attentive, worse than many other our flights with Delta.

Overall good experience; however, there was one flight attendant who was rather rough compared to everyone else. Everything else was good: entertainment, food. Delta keeps on delivering! Thank you!

The flight used a B767 with a very old interior from before 2014. The entertainment system did not work at all during the flight despite attempts to reset the system. It was like they flew this route just to be competitive.

Crew blocked exits to front of ship with galley carts. Also split five person family apart on international flight without fixing.

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

Flight was too crowded and seats are too small, especially since passengrs are getting larger. Having a middle seat is ALWAYS tough! Woman on my left was large & kept creeping in to my space. Flight personnel were great! Have more savory rather than sweet snacks please.

Flight was crowded and the woman sitting on my left was large & kept crouching in to my space. You need bigger seats or smaller passengers to fit into the seats you DO have! Snack were OK. Would appreciate if airlines had more savory rather than sweet snacks, thank you!

Poor, the airline was not able to help me move flights.

Check in -- in business took over 30 mins as there was only one attendant. Boarding was also a mess. The seat was too narrow and was not working properly. Food was very bad and the entertainment very poor. Crew was very polite and helpful, in fairness.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

The flight was late. Please do not delay next time.

Boarding was confusing with a delayed flight because there was no English translation

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

My entertainment did not work. I was very tired from the botched connection, and the poor sleep

It’s a delta flight operated by LATAM. The whole ticket sale is a mess, delta changed my flight but didn’t update it in LATAM system, I couldn’t get my boarding pass, it took me hours to resolve this issue with delta. I had to change my travel plan. No apology from Delta even though it’s their fault.

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

Flight from Rome to SFO was excellent compared To our flight to Europe from SFO. The food was much tastier. You can see how UNITED is skimping, though. Instead of getting something mid flight you had to ask for it. It was not automatically served. There was a cookie at the end of the arrival meal, for example that tasted like it just came out of a box. They used to serve a little container of nuts, now … a tiny container of nuts, mixed with pretzels. This was business class that you really have to pay for! But this is minor complaints compared to the overall. My major complaint is the position of the even numbered seats by the windows. You have to turn around to see your window & the positioning as some other controls are harder to get at. This is compared to the odd number seat that are perfectly aligned.

The person I bought the ticket for didn’t make the flight.

Lately I like the planes have been exceptionally filthy. There’s lines of dust and dirt all across the ceiling in the vents, and the cracks in between the seats are literally full of food. It’s definitely not the quality of service that I was used to with United. I’m also very disappointed with the Wi-Fi! All I wanna do is knock out a few work jobs while I’m trapped in my seat And it spools so bad. They did provide me with a refund, but the process of getting that refund is so complicated. It’s unfortunate.

Another delayed flight. When the delays exceed the duration of the flight, it’s a problem.

Excellent flight. Smooth, efficient boarding. Quick flight. Arrived early at STL.

After boarding the plane in Chicago, the passengers were told that there was a technical problem with the plane. Passengers remained on the plane as they tried to fix the problem. After what was probably an hour passengers were told that there was a need to change planes as the problem was not solved. Passengers disembarked and boarded another plane. After taxing to the runway and waiting for takeoff, passengers were told that owing to the thunderstorm the flight was unable to take off but would try and reroute. After some time passengers were told there wasn't enough fuel for the new route and the plane had to return to the gate for additional fuel. after another log delay the flight got underway. On the plane there was food, drinks, ice or entertainment. We were a glass of water, which appeared rationed. Flight arrived about 5 hours late. The pilot was fantastic and communicated with the passengers throughout the ordeal.

The food quality sucks. One must starve if they do not eat flesh Or wheat based products Some variety would be expected. The trivial amount of snacks and or food is inhumane

Excellent all round, first time flying United. App is very helpful.

We Left Calgary 1/2 hour late and that made for a tight connection in Denver. After arriving everything was done to help us make our connection. That was a great effort. Thank You United

Efficient all round, very good crew. Short flight so the food, of course, was just snacks

The flight was flawless and we even arrived between 20 and 25 minutes early!

Typically flights with AA are good. The staff are pleasant, welcoming, and efficient.

Mostly good. Flight was crowded but Airline personnel were very friendly & accommodating. It would be good to have savory snacks rather than just sweet Biscoff cookies.

We had 3 flights. 1 & 2 were on the same plane but we had to de-board just to re-board 30 mins later. That may have been due to a crew change though. Our 3rd flight had a couple “maintenance” issues that held us up. They were quickly resolved but it took forever for someone to bring the paperwork needed so we could leave. Apparently there was a computer glitch so a driver had to bring a physical copy. It delayed us about 1 1/2 hrs. The flights themselves were smooth & no problems. For boarding, I don’t know why they don’t start with the back of the plane & move forward. It would eliminate the back up from people trying to find their seats & put their bags in the overhead bins. Unless you’re on an overseas flight, there is no food, you get a beverage & either a small bag of pretzels or a biscuit cookie. Take your own food or snacks of you want something more.

We spent too much time on board waiting for takeoff.

The actual trip was fine, however, the changes made to our flights and the layovers were had to endure were awful.

Most things were ok but the main problem was the cabin staff; they were very abrupt and not very friendly. They were busy and often rushed, snatching drinks off people before finished and bossing them about.

Given it’s a red-eye into Charolotte, we didn’t get any food. The survey does not include “N/A” so the rating will be skewed.

The seat was so hard my tailbone was aching The crew was kind of a b**** because I made a joke that I didn't care if they close the door I total c*** when she was trying to f****** act like she was mad at me because I said that The flight was bumpy. Sure you didnt have control over that.

We fly American Airlines quite a bit. And we always fly business class when traveling internationally. We were a bit disappointed with the comfort of this particular plane as well as the entertainment options.

Excessive fees for flight delays. What a Scam. I was not able to attend the wedding I needed to go.

Waited at the airport for over 4 hours to board this flight. Terrible airline

Was supposed to take off 8:00 last night. Got delayed till 8:00 this morning

It was terrible, we had to board and unboard the flight with a hour delay that caused me to miss an appointment and a surprise for my wife

When the flight ticket is expensive and you have to purchase check in luggage and there is no snacks, no entertainment, tight seats stuffed in the back of the plane not such good experience. I would like some to reach out to me . I paid for check luggage when I bought the ticket they made me pay again on the return flight extra $70. Very frustrating.

Excellent experience when I am looking for a budget airline where the main expectation is getting me from point A to point B with no frills.

They didn't let me board with a proper boarding pass. I threw away my bags so that I can board and was defined boarding. Had to take the next flight after paying more.

Great! I intend to use Spirit for future flights. No complaints .

Seats are not very comfortable, maybe a little more padding for a 2hr plus flight

Vegas is such a quick flight that amenities aren’t the important part, in my opinion. Just get me there efficiently and safely, and that’s exactly what they did!

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