$180 Find Cheap Flights from South America to Charlotte

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Charlotte departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$248
Typical prices: $413-$577
Spirit Airlines
Fri 2/6Tue 3/3
MDE - CLT • 1 stop
Cheapest one-way
$180
Typical prices: $376-$662
Spirit Airlines
Tue 5/26
MDE - CLT • 1 stop
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Flight Deals
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Flight Deals

Cheap Flights from South America to Charlotte

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from South America to Charlotte that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from South America to Charlotte

Fri, Feb 6 - Tue, Mar 3
Spirit Airlines Logo
3:15 pm - 12:40 am
MDE
-
CLT
9h 25m
1 stop
Spirit Airlines Logo
5:55 am - 2:13 pm
CLT
-
MDE
8h 18m
1 stop
$248Spirit Airlines
Thu, Feb 5 - Sun, Feb 15
Multiple Airlines Logo
1:26 am - 8:58 pm
GYE
-
CLT
19h 32m
1 stop
Multiple Airlines Logo
8:46 am - 12:04 am
CLT
-
GYE
15h 18m
1 stop
$260Multiple Airlines
Tue, Mar 24 - Sun, Apr 5
Spirit Airlines Logo
2:17 pm - 8:21 am
MDE
-
CLT
17h 04m
1 stop
Spirit Airlines Logo
9:22 pm - 1:22 pm
CLT
-
MDE
17h 00m
1 stop
$266Spirit Airlines
Thu, Feb 5 - Sun, Feb 15
Multiple Airlines Logo
1:26 am - 8:58 pm
GYE
-
CLT
19h 32m
1 stop
Multiple Airlines Logo
8:46 am - 12:04 am
CLT
-
GYE
15h 18m
1 stop
$287Multiple Airlines
Fri, Feb 6 - Tue, Mar 3
Multiple Airlines Logo
6:58 am - 12:40 am
MDE
-
CLT
17h 42m
2 stops
Multiple Airlines Logo
5:55 am - 2:13 pm
CLT
-
MDE
8h 18m
1 stop
$288Multiple Airlines
Sat, May 23 - Sat, Aug 15
GOL Logo
6:00 am - 12:20 am
GRU
-
CLT
19h 20m
2 stops
GOL Logo
2:38 pm - 6:55 am
CLT
-
GRU
15h 17m
2 stops
$628GOL
Sat, May 23 - Sat, Aug 15
GOL Logo
6:00 am - 12:20 am
GRU
-
CLT
19h 20m
2 stops
GOL Logo
2:38 pm - 6:55 am
CLT
-
GRU
15h 17m
2 stops
$629GOL
Thu, Apr 30 - Tue, Jul 14
LATAM Airlines Logo
9:00 pm - 8:41 am
GIG
-
CLT
12h 41m
1 stop
LATAM Airlines Logo
4:30 pm - 6:35 pm
CLT
-
GIG
25h 05m
2 stops
$1,023LATAM Airlines
Sun, May 24 - Fri, Jun 12
Delta Logo
5:20 pm - 1:31 pm
GIG
-
CLT
21h 11m
2 stops
Delta Logo
6:30 pm - 10:15 am
CLT
-
GIG
14h 45m
1 stop
$1,034Delta
Mon, Mar 9 - Fri, Mar 27
LATAM Airlines Logo
10:55 pm - 2:45 pm
GIG
-
CLT
16h 50m
1 stop
LATAM Airlines Logo
4:52 pm - 7:20 am
CLT
-
GIG
13h 28m
1 stop
$1,043LATAM Airlines
Useful Info

Good to know

Low seasonJanuary
Cheapest flight$180
Best time to beat the crowds but there is an average 5% increase in price.
Most popular time to fly and prices are also 6% lower on average.
Flight from Medellín to Charlotte

FAQs for booking flights from South America to Charlotte

  • How does KAYAK find such low prices on flights from South America to Charlotte?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South America to Charlotte.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South America to Charlotte?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Charlotte from South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South America to Charlotte?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Charlotte with an airline and back to South America with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South America to Charlotte?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Charlotte from South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from South America to Charlotte

 
Need help choosing which airline to fly with from South America to Charlotte? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8089 reviews
7.8Entertainment
7.9Comfort
8.5Crew
8.1Boarding
7.2Food
Airline reviews

There was no wifi available on this flight. And there were no screens, no onboard entertainment, no entertainment options at all. It was like travelling in the 1990s again, except without even a main screen for options. Seats, as usual, were tight and uncomfortable.

4.0 OkayJohn, Jan 2026
DAL - ATL
Read more Delta reviews

There was no wifi available on this flight. And there were no screens, no onboard entertainment, no entertainment options at all. It was like travelling in the 1990s again, except without even a main screen for options. Seats, as usual, were tight and uncomfortable.

Good seat comfort ORF to ATL. Bad seat ATL to SEA (terrible lumbar support, hard, ouch)..

Because I was moved to an exit row, the snacks in economy comfort, the selection of snacks was better.

I upgraded to first. Quick and easy boarding. Comfortable seat with power and a nice IPA.

Probably not the fault of Delta but there was delay after delay after delay and I ended up getting home 4 hours later then I should have at 1:30 in the morning

My requested wheelchair never appeared. So many entertainment choices yet, I found little of interest and no internet option to search on my own. Both were minor issues.

No in flight service, no explanation - FC got service, C+ did not, unsure about Economy. No turbulence to speak of, so I guess another way to cut cost, or promote health and well being of Delta employees? Also, boarding in MEM combined zones, and with overhead space already full on both flights after Zone 2/ Diamond, presents a huge challenge to find a space for a bag. Delta, other than point A to B, is no longer reasonable to fly - very poor experiences, not even taking into account the chastising at the gate and rude crews, across the board.

It would have been better if the flight wasn't delayed by 2.5 hours

Delta’s staff is unmatched. From the gate agents, to the pilots, to the flight attendants… all top of the industry.

Delta flight Delay for ,more that two hours i.e original flight was 6.30 PM and it starts at 8.45 PM, When we connect Delta team for meal vouchers as it is late arrival in designation,But we did not get it as per delta policy , which is not good for mid night arrival,

There was a mechanical issue with the plane that they had to work on before we could take off. That's fine, by all means, PLEASE make sure the mechanics are functioning properly. What was a problem was the fact that we sat on the tarmac for 4.5 hours without moving, without letting us off the plane, and without climate control and air running through the plane. There was no explanation as to what was going on; they just kept promising that it would be "15 minutes, then we are on our way." At one point, they even switched the entire crew out and told everyone we just needed to wait for new employees to show up. Then, as the 4 hours were not moving, an hour before the full refund, they made a big show about "the flight starting and the doors are locked, so you have to sit down." We didn't move for another 40 minutes; they were just trying to skirt around legalities that entitled us to restitution. When the flight finally was underway, the plane was gigantic but cramped in design, my entertainment screen kept freezing and glitching, and subtitles didn't work, and the crew was passive-aggressive. Terrible flight.

Comfort in exit seat was excellent. FLight crew and flight were excellent. However exit seat tray table was broken so could not use it. Entertainment monitor did not work at all despite attempts to reset it.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Wish the seats were a little more comfortable.. it was a 6 hrs nonstop trip. But the crew was courteous and w a smile

I like this airline a lot no problems at all, except being forced to check a carry-on bag ., Overall very good airline

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Check in -- in business took over 30 mins as there was only one attendant. Boarding was also a mess. The seat was too narrow and was not working properly. Food was very bad and the entertainment very poor. Crew was very polite and helpful, in fairness.

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

The flight was late. Please do not delay next time.

Mean flight attendant. I wanted to reuse my plastic cup, but he (Matthew) said he can't for safety. I then said "I don't want water then" and he poured me a glass. I hope Matthew gets herpes and spends the rest of his life poor, lonely, and homeless.

Very good. Because of the delays with my previous flight, I missed my connection, but I was able to book another flight through the United app easily.

It was great. There were some issues prior to takeoff. The weather was poor so we had to go through deicing, and we were delayed a bit by the pilots' concern about one of the engines, but that's aviation. The pilots handled everything with aplomb, and kept us apprised

Reliable, nice crew, I fly often on that flight and I like it all.

I wish there were outlets to charge my iPhone. The crew was great; we had a female pilot who was great with explaining what was happening and delays,

The seats were comfortable and we had leg room. Great entertainment.

The flight crew where really good. Better then the crew from BNE to SFO

Delayed, toilets did not flush, pilot parked to far away from Gate

Was happy we finally got upgraded in 1st class. The seat getting old. The cushiness need some improvement.

Safe made to destination. Late to start at GVA for icy reasons but we fought our next fly.

I would like the crew to talk LESS over the PA and specifically about credit card offers. I am trying to work, sleep, watch a movie and the PA was booming about a credit card offer. Could we go back to the days when the customer was more important than selling a credit card?

When I got to the waiting area, it was full but when the time came to board, rgete was no plane. The women where you would show your ticket, gave the news saying there was a maintenance problem and that it be an extra half hour wait. We never did see the plane but ultimately, Noone ever saw the plane because there was a fire on one engine. Needless to say, the wait time before it was announced what really happened, was a few hours. Many, many missed their plane transfer because they entered their first train. Also, the electronic info panels up on the different wall for all to see the status of each flight, never stated anything having to do with the long, long hold up. Many people had major problems because they had to swith planes during their trip and that never happened...

It was a good trip. Flight Attendants were friendly and responsive.

Crew in Columbia was not prepared for landing. It was a bit of a disaster and getting bags took forever.

Tell the crew (when boarding) to yell at the imbeciles blocking us from walking up to scan. I promise everyone crowds around and half of us (most the time I’m group 4) have to push our way through. Your staff is awesome, the public - not so much-

It was fine. My connection in Charlotte to go to WPB was too late and I had to spend the night in the Charlotte Airport in the mini suites.

Nothing to write home about, average flight experience. Seats were spacious enough, crew friendly enough. Loved the AA entertainment/wifi service.

Great flight - friendly and attentive team! Seats in coach were comfy, but a little cramped - but that is the case with all airlines ;)

Experience was good, however I had a delay due to weather happening and had to re purchase a seat on a new plane for a higher price (could be my own issue and misunderstanding) but other than that situation. First time flyer (by myself) was terrific!! The last from ORD to ALO didn't have wifi, but it was only 45 minutes so I'm sure that was part of the reason. Overall my experience was great! Next time I will remember to buy tickets with longer layovers. The delays really saved my overall anxiety. :)

Did not understand a single word the attendant said on the pa system. I was glad it was not an emergency.

Extra legroom with my upgrade bundle. Clean aircraft, on-time departure, early arrival. Good value for the price.

I didn't have a flight because of a ticking problem that was discovered at the airport at checkin for the initial flight of the round trip.

Even though the plane was delayed from the previous airport, the staff recognized this and kept us informed. The flight crew was absolutely awesome from on my flight from Ft. Meyers to AC. Great experience all around!

Flight was delayed would have liked it to have been on time. I didn't experience the food or entertainment but the boarding process was smooth and the flight crew worked well together and did a great job!

Not seat assigned because overbooking. We could go because some people decided to give their seats.

Spirit loves to pick and choose when to harass you about your personal item. I’ve flown numerous times with the same bag with no problem yet flying out of Orlando they forced me to pay $99 for a carry on and then ran out of overhead space. Do better!

For the price of the fare, there really isn’t much to complain about.

didn't order food on board. there's no way to hold a water botton on the way. otherwise it was a pleasant flight, thanks to the crew.

Even though there was a delay the crew was exceptional.

Even though there was a delay the crew was exeptional

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