$186 Find Cheap Flights from South America to Charlotte

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Charlotte departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from South America to Charlotte

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from South America to Charlotte that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from South America to Charlotte

Wed, Oct 8 - Sat, Nov 8
Spirit Airlines Logo
1:16 am - 9:24 amMDE-CLT
7h 08m1 stop
Spirit Airlines Logo
11:00 am - 6:04 pmCLT-MDE
7h 04m1 stop
$266Spirit Airlines
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Wed, Oct 8 - Sat, Nov 8
Spirit Airlines Logo
1:16 am - 9:24 amMDE-CLT
7h 08m1 stop
Spirit Airlines Logo
9:46 pm - 2:16 pmCLT-MDE
16h 30m2 stops
$306Spirit Airlines
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Mon, Dec 1 - Tue, Feb 10
American Airlines Logo
1:30 am - 5:36 pmMDE-CLT
16h 06m1 stop
American Airlines Logo
7:10 am - 8:52 pmCLT-MDE
13h 42m1 stop
$436American Airlines
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Fri, Dec 19 - Thu, Jan 1
American Airlines Logo
1:30 am - 12:26 pmMDE-CLT
10h 56m2 stops
American Airlines Logo
1:15 pm - 11:39 pmCLT-MDE
10h 24m1 stop
$451American Airlines
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Tue, Mar 10 - Wed, Mar 11
LATAM Airlines Logo
11:45 pm - 11:05 amUIO-CLT
10h 20m1 stop
LATAM Airlines Logo
1:15 pm - 5:17 amCLT-UIO
17h 02m2 stops
$471LATAM Airlines
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Tue, Mar 10 - Wed, Mar 11
LATAM Airlines Logo
7:00 pm - 1:56 pmUIO-CLT
17h 56m2 stops
LATAM Airlines Logo
4:30 pm - 5:17 amCLT-UIO
13h 47m2 stops
$477LATAM Airlines
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Mon, Dec 8 - Sun, Mar 22
United Airlines Logo
5:01 am - 9:59 pmCLO-CLT
40h 58m2 stops
United Airlines Logo
4:45 pm - 5:49 pmCLT-CLO
26h 04m2 stops
$546United Airlines
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Sat, Dec 6 - Mon, Mar 23
United Airlines Logo
5:01 am - 10:51 amCLO-CLT
29h 50m2 stops
United Airlines Logo
6:30 am - 5:49 pmCLT-CLO
12h 19m2 stops
$557United Airlines
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Fri, Dec 12 - Tue, Mar 24
Delta Logo
7:57 am - 4:29 pmCLO-CLT
32h 32m2 stops
Delta Logo
7:40 am - 5:30 pmCLT-CLO
10h 50m2 stops
$560Delta
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Tue, Dec 2 - Sat, Jan 31
Delta Logo
4:30 pm - 1:26 pmGYE-CLT
20h 56m2 stops
Delta Logo
4:30 pm - 7:20 amCLT-GYE
14h 50m2 stops
$569Delta
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Everything you should know

Cheapest round-trip
$266
Overall average: $407
Spirit Airlines
Wed 10/8Sat 11/8
MDE - CLT • 1 stop
Cheapest one-way
$186
Typical prices: $177-246
Spirit Airlines
Wed 10/22
MDE - CLT • 1 stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Charlotte!
Useful Info

Good to know

Low seasonFebruary
Cheapest flight$186
Best time to beat the crowds with an average 10% drop in price.
Most popular time to fly and prices are also 5% lower on average.
Flight from Medellín to Charlotte

FAQs for booking flights from South America to Charlotte

  • How does KAYAK find such low prices on flights from South America to Charlotte?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South America to Charlotte.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South America to Charlotte?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Charlotte from South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South America to Charlotte?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Charlotte with an airline and back to South America with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South America to Charlotte?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Charlotte from South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from South America to Charlotte

 
Need help choosing which airline to fly with from South America to Charlotte? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7957 reviews
8.2Boarding
8.5Crew
7.3Food
7.9Comfort
7.9Entertainment
Airline reviews

The staff and the boarding procedure were all amazing . The one flight was not equipped with WIFI which now adays seems odd. All in all the experience was good

8.0 ExcellentAnonymous, Sep 2025GFK - MSP
Read more Delta reviews

The staff and the boarding procedure were all amazing . The one flight was not equipped with WIFI which now adays seems odd. All in all the experience was good

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

Crew was good. The reservation got mixed up and they didn't have my TSA number. I am also a Silver Medallion and wasn't able to use Sky Priority.

The airport crew helped a lot, what I didn’t like? We were not informed that we needed to pick our luggage’s, if the crew at the luggage center didn’t tell me I would have been home without my belongings, I was heading out to my next connecting flight while looking for what gate to go to, I asked one of the crews for help, he told me and he also told me to not forget to grab my luggage’s which was chocking, because on my way out the country that wasn’t required, I just hope none of your customers lost their luggage’s because of this.

Delta made it easy, comfortable and timely. The crew was fantastic.

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

The flight crew was friendly. I tried to adjust my seat online ahead of time but no option existed without additional fees. My friend asked at the gate about a seat change and was able to make it happen. That was great! The flight crew moved a very tall gentleman and his companion which allowed us to have more space which was nice. Overall, good experience. Appreciated the blanket and pillow.

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

My entertainment did not work. I was very tired from the botched connection, and the poor sleep

It’s a delta flight operated by LATAM. The whole ticket sale is a mess, delta changed my flight but didn’t update it in LATAM system, I couldn’t get my boarding pass, it took me hours to resolve this issue with delta. I had to change my travel plan. No apology from Delta even though it’s their fault.

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

entertainment was not good; the shoulder strap on Business class seat did not sit well across the body (more like across the neck); the food was not hot and the special meal promoted by insert in the menu was not available to us

The boarding and new bag drop-off process was confusing and causing massive delays.

Wider seats, better seat cushions, (I felt like there was a board I was sitting on). I had the chicken to eat but It neither tasted nor looked like chicken. The fruit was good.

The newer screen was super cool and had the option to watch many different shows or movies. Crew was polite and helpful. However again, many children screaming bloody murder and kicking my seat, and parents doing nothing about it as usual.

Flight was good and crew was super polite. However, there were around 5 kids screaming the WHOLE 2 hours. I understand kids have to come but parents need to do something to control their children. They make the experience terrible, especially after finishing 16 hour shifts at the hospital I needed some sleep, which I did not get.

IAD with the archaic people movers is just a place to be avoided.

Overall, it was good. I was seating next to a wonderful lady and did not notice how time flew. Thanks

All of the United employees I interacted with were professional and courteous. The aircraft was clean, the food on the flight was good. No complaints here.

Armrest controller on my seat 35D and nextbooennseat 35E did not work right. Hard to press buttons to recognize and 35D had constantnpressure either upmost down somit was nearly impossible to make selections. .

I flew with my dog and had already purchased my dog’s ticket. Even that morning I had called costumer service to insure that my husband and I had seats together since the website was giving me an error when choosing our seats and the representative mentioned our dog. I showed up early to the airport and when I got to the gate and we started boarding I was help back and told that I was supposed to have a yellow tag and that I should have checked in at the counter for them to give me that tag. I was not aware of this, the representative on the phone did not say anything. Nor did I see it anywhere in the checking process online, so if you travel with a pet and are not checking in luggage, just know that you still have to go to the check in counter when arriving at the airport unless you want to be the last one to board and not have room for your carry on in the overhead bins. Other than that, I had a great experience.

Once we got in the air the pilot made up some of the time of the delay. So that was really nice.

My flight was delayed about 1 1/2 hours in Chicago, but other then that it was a good flight.

This is the best united airlines flight that I took. The crew was very friendly and the food was tasty!

Given it’s a red-eye into Charolotte, we didn’t get any food. The survey does not include “N/A” so the rating will be skewed.

The seat was so hard my tailbone was aching The crew was kind of a b**** because I made a joke that I didn't care if they close the door I total c*** when she was trying to f****** act like she was mad at me because I said that The flight was bumpy. Sure you didnt have control over that.

We fly American Airlines quite a bit. And we always fly business class when traveling internationally. We were a bit disappointed with the comfort of this particular plane as well as the entertainment options.

Staff's did their best to make everyone comfortable and I appreciate them for it

The comfort of the seats was great, the crew eased my child’s anxieties and the fact that I had full cans of my beverage choice was great.

We had to turn around and head back to Manchester. Problem with a plane engine.

Overall very good, only complaint I have is the crew from CLT to SAT could have collected trash sooner.

AA re-routed flight from HNL to LAX due to delay. My group of 3 with reserved seats in row 9 was broken up, with one assigned to a middle seat, another in the last row of the plane. Not happy. No explanation to the delay. No apologies. No compensation. Would have been nice to be offered an Admiral Club admission or a voucher for the extra 3 hours of layover in LAX. Could not hear the boarding gate announcements in LAX. Adjacent gate was boarding at the same time. Loud speakers were competing against each other. Barely made my boarding group.

Mechanical delay and no compensation. Missed connection as a result of their delay. Mediocre performance and service. Horrible airline currently with horrible culture.

They cancelled my flight and downgraded me to economy and only gave me $250 for the downgrade

Spirit rescheduled a 4:30 PM flight to 8:52 AM. That's ridiculous and borderline fraud.

Everything was fine. I'm average height and I pack light. I'm ready for my Spirit flight.

Changing the flight time to 6:15 am on the return flight is extremely inconvenient. The flight was okay. It was on time. The crew was friendly. The seats were uncomfortable. All the upsells are annoying, and I would prefer paying a single higher fee and not have to purchase so much extra.

Spirit Airlines was ok but TRAVELHELPDESK, the 3rd party travel agent IS A JOKE! VERY RUDE CUSTOMER AGENTS ont he phone. NO HELP AT ALL. But the airlines was ok.

Cancelled my flight last minute and did not help me rebook. It was a horrible experience.

No frills - because you get what you pay for. The crew was amazing!! I had plenty of room to spread out because the flight was half full. Which made it easy to sleep.

The terminal crew is so rude cabin crew is extremely rude flight is very good

The flight was canceled leaving us scrambling to find another airline. I should have known not to trust Spirit

Spirit is low fare air line. Food also cost you. No free food.

The flight was delayed twice with minimal explanation. The terminal and airplane were filthy. The food voucher didn’t even cover a tiny pizza from a kiosk in the terminal. All in all, a pretty miserable experience for a flight to attend a funeral

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