$189 Find Cheap Flights from South America to Charlotte

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Charlotte departing on 12/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$294
Overall average: $547
Spirit Airlines
Tue 12/23Wed 12/31
CLO - CLT • 1 stop
Cheapest one-way
$189
Typical prices: $235-$283
Spirit Airlines
Tue 12/16
MDE - CLT • 1 stop
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Flight Deals

Cheap Flights from South America to Charlotte

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from South America to Charlotte that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from South America to Charlotte

Tue, Dec 23 - Wed, Dec 31
Spirit Airlines Logo
1:55 am - 9:39 amCLO-CLT
7h 44m1 stop
Spirit Airlines Logo
9:38 pm - 2:15 pmCLT-CLO
16h 37m1 stop
$294Spirit Airlines
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Sat, Dec 13 - Wed, Dec 24
Spirit Airlines Logo
2:05 am - 9:39 amMDE-CLT
7h 34m1 stop
Spirit Airlines Logo
9:34 pm - 10:55 amCLT-MDE
13h 21m1 stop
$325Spirit Airlines
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Thu, Jan 29 - Sat, Feb 28
United Airlines Logo
10:45 am - 9:59 pmMDE-CLT
11h 14m1 stop
United Airlines Logo
5:25 pm - 10:05 pmCLT-MDE
28h 40m2 stops
$476United Airlines
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Wed, Dec 24 - Sun, Jan 18
United Airlines Logo
1:15 am - 9:20 pmMDE-CLT
20h 05m2 stops
United Airlines Logo
7:44 pm - 10:05 pmCLT-MDE
26h 21m2 stops
$502United Airlines
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Fri, Jan 30 - Sun, Feb 1
LATAM Airlines Logo
10:55 pm - 1:45 pmGIG-CLT
16h 50m1 stop
LATAM Airlines Logo
9:59 am - 8:20 amCLT-GIG
20h 21m1 stop
$519LATAM Airlines
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Mon, Feb 2 - Sun, Mar 8
American Airlines Logo
3:20 pm - 9:19 amCLO-CLT
17h 59m1 stop
American Airlines Logo
7:30 pm - 12:55 pmCLT-CLO
18h 25m1 stop
$555American Airlines
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Mon, Feb 2 - Sun, Mar 8
American Airlines Logo
3:20 pm - 1:28 pmCLO-CLT
22h 08m1 stop
American Airlines Logo
10:25 pm - 12:55 pmCLT-CLO
15h 30m1 stop
$556American Airlines
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Sun, Dec 28 - Mon, Jan 12
Delta Logo
4:30 pm - 10:49 amGYE-CLT
18h 19m1 stop
Delta Logo
1:13 pm - 7:20 amCLT-GYE
18h 07m2 stops
$569Delta
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Wed, Jan 21 - Wed, Jan 28
Delta Logo
4:30 pm - 9:18 amGYE-CLT
16h 48m1 stop
Delta Logo
2:25 pm - 7:20 amCLT-GYE
16h 55m1 stop
$581Delta
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Tue, Apr 7 - Fri, May 22
LATAM Airlines Logo
11:30 pm - 11:05 amUIO-CLT
10h 35m1 stop
LATAM Airlines Logo
6:59 pm - 7:05 pmCLT-UIO
25h 06m2 stops
$613LATAM Airlines
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Good to know

Low seasonOctober
Cheapest flight$189
Best time to beat the crowds but there is an average 4% increase in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Medellín to Charlotte

FAQs for booking flights from South America to Charlotte

  • How does KAYAK find such low prices on flights from South America to Charlotte?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South America to Charlotte.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South America to Charlotte?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Charlotte from South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South America to Charlotte?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Charlotte with an airline and back to South America with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South America to Charlotte?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Charlotte from South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from South America to Charlotte

 
Need help choosing which airline to fly with from South America to Charlotte? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8003 reviews
8.5Crew
7.9Comfort
8.1Boarding
7.9Entertainment
7.3Food
Airline reviews

Flight delayed then cancelled. Misplaced luggage. Still do not have. Rented car 1100 mile drive. I had to buy some overnight Hotels clothes toiletries gas food at my expense. Still not home. Not sure where luggage is. Over 4 hours on hold to Felta

2.0 MediocreAnonymous, Nov 2025MOB - ATL
Read more Delta reviews

Flight delayed then cancelled. Misplaced luggage. Still do not have. Rented car 1100 mile drive. I had to buy some overnight Hotels clothes toiletries gas food at my expense. Still not home. Not sure where luggage is. Over 4 hours on hold to Felta

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

Everything went well and was good. Nothing exceptional, but no complaints either. Cheap seats are pretty comfortable.

DELTA does a terrific job making sure you are well taken care of during the flight, gives you assurance before the flight through numerous email notifications about your upcoming flight & lastly good follow up after the flight making sure your needs were mat. It has been, is & will continue to be my carrier of choice in all my future travels. Good Job DELTA

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

The customer service before board was very rude and when I expressed my concerns about making the connecting flight she laughed and told me I bought the wrong ticket. I explained once it showed the flight was delayed it no longer let me change seats or anything. I was trying to upgrade to make sure I would get to the next gate on time.

Non stop on long haul is the way to go. Great experience

Seats comfortable, service and food very mediocre, staff not very attentive, worse than many other our flights with Delta.

I like this airline a lot no problems at all, except being forced to check a carry-on bag ., Overall very good airline

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Check in -- in business took over 30 mins as there was only one attendant. Boarding was also a mess. The seat was too narrow and was not working properly. Food was very bad and the entertainment very poor. Crew was very polite and helpful, in fairness.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

The flight was late. Please do not delay next time.

Boarding was confusing with a delayed flight because there was no English translation

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

My entertainment did not work. I was very tired from the botched connection, and the poor sleep

It’s a delta flight operated by LATAM. The whole ticket sale is a mess, delta changed my flight but didn’t update it in LATAM system, I couldn’t get my boarding pass, it took me hours to resolve this issue with delta. I had to change my travel plan. No apology from Delta even though it’s their fault.

Older aircraft, no meal, only food was for purchase. Not impressed United.

United needs to step up their game. Delayed flight leaving Seattle, San Francisco. Older aircraft, not very comfortable.

Always wish for more healthy, gluten free options. We have to bring our own.

Having a long layover, I was very appreciative of the ability to stand by for an earlier flight. Other airlines like Delta have refused this to me in the past, just to be mean (because my ticket class wasn't high enough). United went out of their way to help me get to my destination early, which I really appreciated given that it was the third leg of a 24+ hour journey for me.

This flight leg was fantastic - super comfortable and a great selection of things to watch on the TV. Staff were excellent, really above and beyond.

Other than a way way too cold cabinets for the entire flight, all was great

One bag is incorrect and not acceptable for an international flight. The food was not just good. I won't fly with them again.

The flight attendants were very rude, beyond comprehension. I took a business class from London to SFO for the first time on United. When I asked for a second piece of bread during dinner, the serving attendant threw a 3rd bread on my plate and said, “here. You can have this one too”! I couldn’t believe the rudeness of the attendant. Most all attendants were very rude, unhelpful, sing the food was absolutely disgusting. Never fly United internationally in business class. My flight back to SFO was a nightmare!!

Not pleasant trip cross country when the entertainment and WiFi system not working. No entertainment for entirety of route. Staff was rather nonchalant in that they dismissed the problem due to age of plane. It would have been nice to know this up front so I could have come prepared to read or download movies before boarding Coincidentally or not, there was a similar issue with the entertainment system on my previous flight I took on my fist leg of the trip. There are no seat TVs, so you must rely on the app when it works. United can do better. Also, what use it it to pay for boarding group 2 when half of the passengers are in the same line as you?

Plane boarded early a quickly, was mostly full. We left close to on time. And landed early.

Did not get any refreshments. Crew was very nice but limited. Small seats

The flight was flawless and we even arrived between 20 and 25 minutes early!

Typically flights with AA are good. The staff are pleasant, welcoming, and efficient.

Mostly good. Flight was crowded but Airline personnel were very friendly & accommodating. It would be good to have savory snacks rather than just sweet Biscoff cookies.

We had 3 flights. 1 & 2 were on the same plane but we had to de-board just to re-board 30 mins later. That may have been due to a crew change though. Our 3rd flight had a couple “maintenance” issues that held us up. They were quickly resolved but it took forever for someone to bring the paperwork needed so we could leave. Apparently there was a computer glitch so a driver had to bring a physical copy. It delayed us about 1 1/2 hrs. The flights themselves were smooth & no problems. For boarding, I don’t know why they don’t start with the back of the plane & move forward. It would eliminate the back up from people trying to find their seats & put their bags in the overhead bins. Unless you’re on an overseas flight, there is no food, you get a beverage & either a small bag of pretzels or a biscuit cookie. Take your own food or snacks of you want something more.

We spent too much time on board waiting for takeoff.

The actual trip was fine, however, the changes made to our flights and the layovers were had to endure were awful.

Most things were ok but the main problem was the cabin staff; they were very abrupt and not very friendly. They were busy and often rushed, snatching drinks off people before finished and bossing them about.

Given it’s a red-eye into Charolotte, we didn’t get any food. The survey does not include “N/A” so the rating will be skewed.

The seat was so hard my tailbone was aching The crew was kind of a b**** because I made a joke that I didn't care if they close the door I total c*** when she was trying to f****** act like she was mad at me because I said that The flight was bumpy. Sure you didnt have control over that.

The pilot would speak it was painfully load a d the crew had to know this! Maybe the were hesitant to tell him. It was just a mediocre experience and I was in Spirit first class!

My flight was cancelled last minute and I had to pay $1600 for flights, when my original flights were $300. It was a terrible experience.

Boarding was easy. I loved that they sat our family together even though we didn't pay for specific seats. I thought $5+ was a lot for pretzels and wish they had a small free snack.

The Hawaiian lady that boarded me was rude and the one help me a the ticket counter was rude

My experience was terrible. They cancelled my flight twice. They kept delaying it and leading me on, acting like the flight was going to go when it never had a chance. I missed out on valuable family time because of spirit and I won’t be flying with them again.

Prices for bags are extremely expensive and if you go higher on weight, the charge is ridiculous.

The flight was cancelled at the last minute. Will never fly Spirit again. Without a doubt the worst airline around.

My flight was delayed several times and eventually cancelled. Then the re-booked flight for 8pm was delayed multiple times over, and eventually it would have forced me to be at the airport for 9 hours. I accepted a rebook for the following day, fortunately I was able to stay with my friend again in New York, but if I didn’t have him as a resource it would have been much more upsetting.

Horrible, delay after delay due to our plane needing fuel.

Rough landings but comfortable and affordable if you can pack light

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