TYR - TYS

$448 Find Cheap Flights from Tyler to Knoxville

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Tyler to Knoxville departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Tyler to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Tyler to Knoxville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$448
American Airlines
ש' 4/25ש' 5/2
TYR - TYS • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Tyler and Knoxville. You'll need at least 1 connection.
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Tyler to Knoxville (TYR-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Tyler to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Tyler to Knoxville

ש', אפר' 25 - ש', מאי 2
American Airlines Logo
5:55 pm - 11:56 pm
TYR
-
TYS
5h 01m
1 stop
American Airlines Logo
6:54 pm - 11:47 pm
TYS
-
TYR
5h 53m
1 stop
$448American Airlines
ש', אפר' 25 - ש', מאי 2
American Airlines Logo
10:41 am - 6:04 pm
TYR
-
TYS
6h 23m
1 stop
American Airlines Logo
4:15 pm - 11:47 pm
TYS
-
TYR
8h 32m
2 stops
$454American Airlines
ש', אפר' 25 - ש', מאי 2
American Airlines Logo
10:41 am - 11:55 pm
TYR
-
TYS
12h 14m
2 stops
American Airlines Logo
8:00 am - 5:25 pm
TYS
-
TYR
10h 25m
2 stops
$459American Airlines
ה', אפר' 9 - א', אפר' 12
American Airlines Logo
5:55 pm - 11:56 pm
TYR
-
TYS
5h 01m
1 stop
American Airlines Logo
6:00 am - 10:11 am
TYS
-
TYR
5h 11m
1 stop
$592American Airlines
ו', אפר' 10 - ב', אפר' 13
American Airlines Logo
10:41 am - 9:40 pm
TYR
-
TYS
9h 59m
2 stops
American Airlines Logo
6:54 pm - 11:47 pm
TYS
-
TYR
5h 53m
1 stop
$598American Airlines
ה', אפר' 9 - א', אפר' 12
American Airlines Logo
5:55 pm - 11:56 pm
TYR
-
TYS
5h 01m
1 stop
American Airlines Logo
8:00 am - 5:25 pm
TYS
-
TYR
10h 25m
2 stops
$813American Airlines
ו', אפר' 10 - ב', אפר' 13
American Airlines Logo
10:41 am - 9:40 pm
TYR
-
TYS
9h 59m
2 stops
American Airlines Logo
2:06 pm - 11:47 pm
TYS
-
TYR
10h 41m
2 stops
$818American Airlines
ה', אפר' 9 - ב', אפר' 13
American Airlines Logo
10:41 am - 9:40 pm
TYR
-
TYS
9h 59m
2 stops
American Airlines Logo
3:58 pm - 11:47 pm
TYS
-
TYR
8h 49m
2 stops
$941American Airlines
Booking Insights

Good to know

Cheapest flight$448
Flight from Tyler to Knoxville

When to book flights from Tyler to Knoxville

Are your dates flexible? Find out the best times to travel from Tyler to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Tyler to Knoxville

  • What is the cheapest flight from Tyler to Knoxville?

    In the last 3 days, the lowest price for a flight from Tyler to Knoxville was $448 for a round-trip ticket.

  • Do I need a passport to fly between Tyler and Knoxville?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from Tyler to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Tyler to Knoxville?

    oneworld is the only airline alliance operating flights between Tyler and Knoxville.

  • How does KAYAK find such low prices on flights from Tyler to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Tyler to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Tyler to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Tyler is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Tyler to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Tyler with another airline. Booking your flights between Tyler and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Tyler to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Tyler up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Tyler to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Tyler to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Tyler to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11521 reviews
7.5Boarding
7.9Crew
7.2Comfort
6.4Food
6.9Entertainment
Airline reviews

The flight changed gates multiple times and flight had to be delayed multiple times

4.0 OkayFaraz, Mar 2026
DFW - BWI
Read more American Airlines reviews

The flight changed gates multiple times and flight had to be delayed multiple times

Delayed for mechanical and no updates on what was happening and how long the delay might be.

On the return flight, arriving in Denver we sat on the tarmac in Denver for over 20 minutes.

Absolutely terrible. Would never fly American again. 2 deplaned incidents and delayed by close to 24 hours. $12 meal voucher for first class passengers was an insult to the injury. Pathetic.

Mostly good. The WiFi wasn’t working so that was not great.

I rated the experience "mediocre" because of the 2 hour delay in take off. This is the 4th flight from DFW on AA where there was a delay and in one of the instances (after 13 delays), the flight was cancelled. I understand weather but for the March 18th flight, there was no weather issue in Dallas or Detroit. I called Concierge Key and they were wonderful, booking me on a later flight in case my flight was cancelled. I have flown with American for many years and never has there been this consistent pattern of delays. Very disappointing.

As a first class customer, there was no power the entire flight which limited my ability to work. I find this unacceptable. The first 11 rows on the left side of the plan were out. I was only offered the option to charge my phone which was not the issue because my laptop was out of power. I asked if there was anything that can be done for me, and the answer was, "no". I was not offered any type of compensation for this AA problem which caused me unnecessary stress due to inability to address business issues on an already challenging travel day. Flight attendants tried to reset the power once but that was the extent of their support. Very disappointing for the lack of expected services on a flight. Please contact me with customer focused response to this complaint.

Easy boarding. Rows are smaller but that may be an older and bigger me now :)

Check in was rough because the check in crew did not know how to manage my international visa documents. Required a long process and 4 people to finally be able to proceed to security. They told us incorrect information several times before acknowledging we did indeed have everything we needed from the start.

Poor communication ahead of time about flight delays and old planes/other equipment.

Everything you need to know for your flight from Tyler to Knoxville

Information on your arrival and departure airports

Tyler (TYR)
Knoxville (TYS)