$379 Find Cheap Flights from Prague to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Prague to South Carolina departing on 2/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Prague to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Prague to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Prague to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston2 stops$853
Myrtle Beach
Myrtle Beach2 stops$853
Columbia
Columbia2 stops$851
Florence
Florence2 stops$864
Charlotte
Charlotte2 stops$630
Charleston
Charleston2 stops$853
Myrtle Beach
Myrtle Beach2 stops$853
Columbia
Columbia2 stops$851
Florence
Florence2 stops$864
Charlotte
Charlotte2 stops$630

Book Cheap Prague to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Prague to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Prague to South Carolina

Wed, Feb 4 - Tue, May 12
Multiple Airlines Logo
2:40 pm - 9:30 am
PRG
-
CLT
48h 50m
2 stops
Multiple Airlines Logo
6:40 pm - 4:05 pm
CLT
-
PRG
15h 25m
1 stop
$630Multiple Airlines
Sat, Mar 7 - Sat, Mar 14
Multiple Airlines Logo
12:30 pm - 9:17 am
PRG
-
CLT
26h 47m
3 stops
Multiple Airlines Logo
9:07 pm - 11:20 am
CLT
-
PRG
33h 13m
2 stops
$724Multiple Airlines
Sat, Mar 7 - Sat, Mar 14
Multiple Airlines Logo
8:50 pm - 10:59 pm
PRG
-
CLT
32h 09m
3 stops
Multiple Airlines Logo
9:18 am - 2:20 pm
CLT
-
PRG
24h 02m
3 stops
$764Multiple Airlines
Mon, Feb 2 - Tue, May 12
Multiple Airlines Logo
2:20 pm - 11:59 pm
PRG
-
CLT
39h 39m
2 stops
Multiple Airlines Logo
6:40 pm - 4:05 pm
CLT
-
PRG
15h 25m
1 stop
$807Multiple Airlines
Thu, Feb 5 - Mon, Feb 9
American Airlines Logo
10:30 am - 7:05 pm
PRG
-
CLT
14h 35m
1 stop
American Airlines Logo
11:15 pm - 10:50 pm
CLT
-
PRG
17h 35m
1 stop
$843American Airlines
Thu, Feb 5 - Mon, Feb 9
American Airlines Logo
6:45 am - 2:15 pm
PRG
-
CLT
13h 30m
1 stop
American Airlines Logo
6:37 pm - 5:30 pm
CLT
-
PRG
16h 53m
2 stops
$848American Airlines
Fri, Feb 6 - Tue, Feb 10
United Airlines Logo
7:35 am - 8:02 pm
PRG
-
CHS
18h 27m
2 stops
United Airlines Logo
2:58 pm - 1:55 pm
CHS
-
PRG
16h 57m
2 stops
$947United Airlines
Fri, Feb 6 - Tue, Feb 10
Scandinavian Airlines Logo
10:25 am - 10:22 pm
PRG
-
CHS
17h 57m
2 stops
Scandinavian Airlines Logo
6:00 am - 9:45 am
CHS
-
PRG
21h 45m
3 stops
$948Scandinavian Airlines
Thu, Feb 12 - Sun, Feb 15
United Airlines Logo
7:35 am - 6:58 pm
PRG
-
CAE
17h 23m
2 stops
United Airlines Logo
3:32 pm - 10:25 pm
CAE
-
PRG
24h 53m
2 stops
$954United Airlines
Fri, Feb 6 - Tue, Feb 10
Air Canada Logo
7:35 am - 11:48 pm
PRG
-
CHS
22h 13m
3 stops
Air Canada Logo
11:00 am - 1:55 pm
CHS
-
PRG
20h 55m
3 stops
$1,195Air Canada
Booking Insights

KAYAK's insights & trends for Prague to South Carolina flights

Get data-powered insights and trends into flights from Prague to South Carolina to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Prague to South Carolina?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Prague to South Carolina were found on American Airlines ($843) and KLM ($939).

Good to know

Cheapest flight$379
Flight from Prague to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Prague to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Prague to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Prague to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Prague to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Prague to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Prague to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Prague to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Prague to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Prague to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Prague to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Prague to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8094 reviews
7.2Food
7.9Comfort
7.8Entertainment
8.1Boarding
8.5Crew
Airline reviews

Connection through Atlanta was difficult. Mechanical issue on plane caused a two hour delay. New gate was a mile away.

4.0 OkayDave, Jan 2026
RSW - ATL
Read more Delta reviews

Connection through Atlanta was difficult. Mechanical issue on plane caused a two hour delay. New gate was a mile away.

No WiFi. Comfort plus should have alcohol provided, crew only offered water or tea. Who the heck wants tea?

The flight was delayed and oversold. I volunteered to give up my seat for compensation. Thinking I could get a good night's sleep instead of arriving home at 2 am. It took over an hour to get the new reservation confirmed, three different gate attendants, and two red coats. It took even longer to confirm the overnight hotel, and when I arrived, the line was 45 minutes long, with two people checking in, and at least 15 people slowly, very slowly—no food except frozen convenience food, no coupon for food from airlines. Slept, headed back to the airport, and that flight had an equipment change and a gate change just as they were about to board. It took an additional hour to board as they cleaned the plane from storage.

There was no wifi available on this flight. And there were no screens, no onboard entertainment, no entertainment options at all. It was like travelling in the 1990s again, except without even a main screen for options. Seats, as usual, were tight and uncomfortable.

Good seat comfort ORF to ATL. Bad seat ATL to SEA (terrible lumbar support, hard, ouch)..

Because I was moved to an exit row, the snacks in economy comfort, the selection of snacks was better.

I upgraded to first. Quick and easy boarding. Comfortable seat with power and a nice IPA.

Probably not the fault of Delta but there was delay after delay after delay and I ended up getting home 4 hours later then I should have at 1:30 in the morning

My requested wheelchair never appeared. So many entertainment choices yet, I found little of interest and no internet option to search on my own. Both were minor issues.

No in flight service, no explanation - FC got service, C+ did not, unsure about Economy. No turbulence to speak of, so I guess another way to cut cost, or promote health and well being of Delta employees? Also, boarding in MEM combined zones, and with overhead space already full on both flights after Zone 2/ Diamond, presents a huge challenge to find a space for a bag. Delta, other than point A to B, is no longer reasonable to fly - very poor experiences, not even taking into account the chastising at the gate and rude crews, across the board.

Unfortunately weather delayed our flight waiting for our plane to arrive and due to a little snow time was needed to deice the plane so departure was very delayed and I missed the connecting flight

Mean flight attendant. I wanted to reuse my plastic cup, but he (Matthew) said he can't for safety. I then said "I don't want water then" and he poured me a glass. I hope Matthew gets herpes and spends the rest of his life poor, lonely, and homeless.

Very good. Because of the delays with my previous flight, I missed my connection, but I was able to book another flight through the United app easily.

It was great. There were some issues prior to takeoff. The weather was poor so we had to go through deicing, and we were delayed a bit by the pilots' concern about one of the engines, but that's aviation. The pilots handled everything with aplomb, and kept us apprised

Reliable, nice crew, I fly often on that flight and I like it all.

I wish there were outlets to charge my iPhone. The crew was great; we had a female pilot who was great with explaining what was happening and delays,

The seats were comfortable and we had leg room. Great entertainment.

The flight crew where really good. Better then the crew from BNE to SFO

Delayed, toilets did not flush, pilot parked to far away from Gate

Was happy we finally got upgraded in 1st class. The seat getting old. The cushiness need some improvement.

Everything you need to know for your flight from Prague to South Carolina

Information on your arrival and departure airports