$347 Find Cheap Flights from Prague to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Prague to South Carolina departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Prague to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Prague to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Prague to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston2 stops$855
Myrtle Beach
Myrtle Beach2 stops$738
Columbia
Columbia2 stops$868
Florence
Florence2 stops$866
Charlotte
Charlotte2 stops$587
Charleston
Charleston2 stops$855
Myrtle Beach
Myrtle Beach2 stops$738
Columbia
Columbia2 stops$868
Florence
Florence2 stops$866
Charlotte
Charlotte2 stops$587

Book Cheap Prague to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Prague to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Prague to South Carolina

Mon, Apr 27 - Tue, May 12
Multiple Airlines Logo
9:55 pm - 11:49 pm
PRG
-
CLT
31h 54m
2 stops
Multiple Airlines Logo
6:40 pm - 4:05 pm
CLT
-
PRG
15h 25m
1 stop
$587Multiple Airlines
Tue, Apr 28 - Tue, May 12
Multiple Airlines Logo
7:10 am - 10:17 am
PRG
-
CLT
33h 07m
2 stops
Multiple Airlines Logo
6:40 pm - 4:05 pm
CLT
-
PRG
15h 25m
1 stop
$592Multiple Airlines
Wed, Apr 29 - Tue, May 12
Multiple Airlines Logo
9:25 am - 11:59 am
PRG
-
CLT
32h 34m
2 stops
Multiple Airlines Logo
6:40 pm - 4:05 pm
CLT
-
PRG
15h 25m
1 stop
$596Multiple Airlines
Mon, Apr 27 - Mon, May 11
Multiple Airlines Logo
9:55 pm - 11:49 pm
PRG
-
CLT
31h 54m
2 stops
Multiple Airlines Logo
6:40 pm - 12:45 pm
CLT
-
PRG
12h 05m
1 stop
$598Multiple Airlines
Fri, Feb 6 - Sun, Feb 8
American Airlines Logo
6:00 am - 11:58 pm
PRG
-
SAV
23h 58m
2 stops
American Airlines Logo
5:21 pm - 1:35 pm
SAV
-
PRG
14h 14m
2 stops
$855American Airlines
Fri, Feb 6 - Sun, Feb 8
American Airlines Logo
6:00 am - 6:49 pm
PRG
-
MYR
18h 49m
2 stops
American Airlines Logo
1:53 pm - 1:35 pm
MYR
-
PRG
17h 42m
2 stops
$855American Airlines
Sun, Mar 1 - Sun, Mar 8
United Airlines Logo
7:25 am - 9:55 pm
PRG
-
SAV
20h 30m
2 stops
United Airlines Logo
2:15 pm - 1:05 pm
SAV
-
PRG
17h 50m
2 stops
$948United Airlines
Sat, Jul 11 - Sat, Jul 25
United Airlines Logo
6:00 am - 9:47 am
PRG
-
CAE
33h 47m
2 stops
United Airlines Logo
10:18 am - 1:55 pm
CAE
-
PRG
21h 37m
2 stops
$1,038United Airlines
Sat, Feb 28 - Sat, Mar 7
Scandinavian Airlines Logo
10:25 am - 11:57 pm
PRG
-
SAV
19h 32m
2 stops
Scandinavian Airlines Logo
7:00 am - 9:45 am
SAV
-
PRG
20h 45m
3 stops
$1,123Scandinavian Airlines
Thu, Feb 12 - Thu, Feb 19
Air Canada Logo
11:50 am - 12:19 pm
PRG
-
MYR
30h 29m
3 stops
Air Canada Logo
1:00 pm - 1:05 pm
MYR
-
PRG
18h 05m
3 stops
$1,503Air Canada
Booking Insights

KAYAK's insights & trends for Prague to South Carolina flights

Get data-powered insights and trends into flights from Prague to South Carolina to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Prague to South Carolina?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Prague to South Carolina were found on American Airlines ($855) and United Airlines ($948).

Good to know

Cheapest flight$347
Flight from Prague to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Prague to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Prague to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Prague to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Prague to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Prague to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Prague to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Prague to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Prague to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Prague to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Prague to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Prague to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8051 reviews
7.2Food
7.8Entertainment
8.1Boarding
8.5Crew
7.9Comfort
Airline reviews

Departure was delayed resulting in me missing my connection. Delta did not autimatically find me another flight.

4.0 OkayNeal, Jan 2026
SEA - SLC
Read more Delta reviews

Departure was delayed resulting in me missing my connection. Delta did not autimatically find me another flight.

The seats weren’t reclining even though it wasn’t as exit seat

It was good because we traveled without luggage, carry on only.

We departed late, and we arrived to Atlanta late for our connecting flight to Quito. I asked the flight attendant before landing to please make an announcement and let us go out of the plane first she agreed but never did the announcement. We run and arrived 3 minutes late and they closed the gate of the plane. We ended up staying one day in Atlanta for the next flight to Quito. When we arrived to Quito 2 of our 50lbs bags arrived completely broken and destroyed. I made the complaint and so far nobody in Delta wants to help.

I usually get upgraded so my experience is usually amazing. I did not get upgraded this time - which was fine - but the wifi had issues, the monitors were going in & out, & (though not Delta's fault) one of the gentlemen next to me desperately needed a shower.

The entertainment screens were not working and there was no air condition the entire flight. Very uncomfortable.

I have diamond medallion status and usually we are in comfort plus . We were in main this time ( which was fine ) and my husband wanted wine . I have at least 10 vouchers for drinks that are good for this year and next! The attendant would not take the picture of the voucher as proof and never came back to check as She asked me to pull it up on delta Wi-Fi. Instead my husband just used his Amex to buy the wine . Disappointing!!!

Food is basically Sun Chips, cookies or Cheezits. I had an exit row seat so I had plenty of room. The crew was very nice and efficient. Pilot kept us informed. Pretty good flight.

Air travel sucks. It continues to be awful for all airlines. No shame on delta alone.

It was Delta, but the flight attendants were stressful and disrespectful. I am a diamond member a travel weekly. I have not had a negative thing to share in quite some time. But this was noticeable.

Was happy we finally got upgraded in 1st class. The seat getting old. The cushiness need some improvement.

Safe made to destination. Late to start at GVA for icy reasons but we fought our next fly.

I just think it’s unfortunate that Airlines have completely abandoned the idea of serving any kind of decent or even real food on flights, not even on a four hour flight!? Those days are gone, I guess.

Yet another flight in which beverage and snack service was skipped. Other that that, firmly mediocre. Landed early, to gate late due to congestion at the gates. Airline's fault or airports fault: unknown.

Miserable. They moved my seat, but canceled the next leg of my flight. I resolved the issue at my transfer, but that resulted in lost luggage that has taken days off my schedule with no resolution. Worse, they fail to interface effectively with Lufthansa, forcing me to bounce between two equally useless help desks. The apps are unable to handle the situation, the bag dropped off the tracker, and while the call centers are polite, they do not provide written information to assist with cross-airline communication.

Both flights delayed. 2nd flight over 3 hours late mechanical issues

l really enjoy very much the flight was very pleasant

left on time, reasonable boarding process arrived early luggage came out quickly

I like flying first class, and United has a nice one

Flight was delayed 45 minutes because originating flight was coming from Newark. No complimentary snacks were offered on this 5+ hour flight. No screens for the flight, but movies offered if you had already downloaded the United app (which I hadn't on my ipad). No USB ports, only a flimsy plug-in port near the bottom of the seat that was hard to see and kept coming unplugged.

Everything you need to know for your flight from Prague to South Carolina

Information on your arrival and departure airports