$123 Find Cheap Flights from Reagan Washington National Airport to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Reagan-National to South America departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from Reagan-National to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$384
Bogotá
Bogotá1 stop$343
Sao Paulo
Sao Paulo2 stops$680
Santiago
Santiago2 stops$519
Cartagena
Cartagena2 stops$331
Quito
Quito1 stop$390
Guayaquil
Guayaquil2 stops$379
Cali
Cali1 stop$363
Cusco
Cusco2 stops$591
Pereira
Pereira2 stops$411
Georgetown
Georgetown2 stops$482
Montevideo
Montevideo2 stops$656
Barranquilla
Barranquilla2 stops$310
Asuncion
Asuncion2 stops$610
Lima
Lima1 stop$384
Bogotá
Bogotá1 stop$343
Sao Paulo
Sao Paulo2 stops$680
Santiago
Santiago2 stops$519
Cartagena
Cartagena2 stops$331
Quito
Quito1 stop$390
Guayaquil
Guayaquil2 stops$379
Cali
Cali1 stop$363
Cusco
Cusco2 stops$591
Pereira
Pereira2 stops$411
Georgetown
Georgetown2 stops$482
Montevideo
Montevideo2 stops$656
Barranquilla
Barranquilla2 stops$310
Asuncion
Asuncion2 stops$610

Book Cheap Reagan-National to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Reagan-National to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Reagan-National to South America

Mon, Feb 2 - Thu, Feb 5
JetBlue Logo
7:30 am - 2:55 pm
DCA
-
MDE
7h 25m1 stop
JetBlue Logo
2:25 pm - 10:31 pm
MDE
-
DCA
8h 06m1 stop
$297JetBlue
Sat, Jan 31 - Wed, Feb 4
American Airlines Logo
5:00 am - 9:10 pm
DCA
-
MDE
16h 10m1 stop
American Airlines Logo
7:00 am - 12:34 am
MDE
-
DCA
17h 34m1 stop
$299American Airlines
Sun, Feb 1 - Thu, Feb 5
United Airlines Logo
8:15 am - 10:05 pm
DCA
-
MDE
13h 50m1 stop
United Airlines Logo
10:45 am - 10:06 pm
MDE
-
DCA
11h 21m1 stop
$303United Airlines
Wed, Feb 4 - Sat, Feb 14
United Airlines Logo
12:40 pm - 10:05 pm
DCA
-
MDE
9h 25m1 stop
United Airlines Logo
10:45 am - 8:56 pm
MDE
-
DCA
10h 11m1 stop
$327United Airlines
Wed, Jan 28 - Mon, Feb 2
LATAM Airlines Logo
10:15 am - 7:30 pm
DCA
-
BOG
9h 15m1 stop
LATAM Airlines Logo
8:35 am - 10:09 pm
BOG
-
DCA
13h 34m1 stop
$343LATAM Airlines
Tue, Jan 20 - Thu, Jan 29
LATAM Airlines Logo
6:00 am - 2:25 pm
DCA
-
BOG
8h 25m1 stop
LATAM Airlines Logo
7:00 am - 6:29 pm
BOG
-
DCA
11h 29m2 stops
$348LATAM Airlines
Wed, Jan 21 - Mon, Feb 2
Delta Logo
10:15 am - 7:30 pm
DCA
-
BOG
9h 15m1 stop
Delta Logo
9:00 am - 6:29 pm
BOG
-
DCA
9h 29m1 stop
$353Delta
Tue, Jan 20 - Fri, Jan 23
Delta Logo
6:00 am - 2:17 pm
DCA
-
CTG
8h 17m1 stop
Delta Logo
3:32 pm - 11:36 pm
CTG
-
DCA
8h 04m1 stop
$356Delta
Sat, Jan 24 - Sat, Jan 31
Air Canada Logo
4:15 pm - 5:45 pm
DCA
-
SDU
23h 30m2 stops
Air Canada Logo
11:20 am - 10:23 am
SDU
-
DCA
25h 03m2 stops
$593Air Canada
Tue, May 5 - Tue, May 12
Air Canada Logo
4:30 pm - 4:45 pm
DCA
-
SDU
23h 15m2 stops
Air Canada Logo
1:45 pm - 6:02 pm
SDU
-
DCA
29h 17m2 stops
$633Air Canada
Booking Insights

KAYAK's insights & trends for Reagan-National to South America flights

Get data-powered insights and trends into flights from Reagan-National to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Washington, D.C. Reagan-National Airport to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Washington, D.C. Reagan-National Airport to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Washington, D.C. Reagan-National Airport to South America is October, when tickets cost $485 (return) on average. On the other hand, the most expensive months are July and December, when the average cost of round-trip tickets is $718 and $702 respectively.

What’s the cheapest day of the week to fly from Reagan Washington National Airport to South America?

The average price of all round-trip flights from Washington, D.C. Reagan-National Airport to South America clicked on KAYAK for each day over the last 12 months.

For Reagan Washington National Airport to South America, Wednesday is the cheapest day to fly on average and Saturday is the most expensive. Flying from South America back to Reagan Washington National Airport, the best deals are generally found on Tuesday, with Saturday being the most expensive.

How far in advance should I book a flight from Washington, D.C. Reagan-National Airport to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Washington, D.C. Reagan-National Airport to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Washington, D.C. Reagan-National Airport to South America, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Good to know

Low seasonNovember
Cheapest flight$123
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 29% increase in price.
Flight from Reagan Washington National Airport to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Reagan Washington National Airport to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Reagan Washington National Airport to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Reagan Washington National Airport to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Reagan Washington National Airport to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Reagan Washington National Airport to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Reagan Washington National Airport to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Reagan Washington National Airport to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Reagan Washington National Airport to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the evening, when round-trip flights cost $594 on average. Morning departures are around 8% more expensive than evening flights, on average. The most expensive time of day to fly to South America is generally at night, which is peak travel time and where the average cost of a ticket is $649.

Reviews of the top 5 airlines serving from Reagan-National to South America

 
Need help choosing which airline to fly with from Reagan-National to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8009 reviews
7.9Comfort
7.3Food
8.1Boarding
8.5Crew
7.9Entertainment
Airline reviews

Lady Pilot was perfect in every way wheels up to wheels down communication, professionalism, excellent on time departure and on time arrival, excellent communication! Fantastic job with Superb attitude!!

10.0 ExcellentVenkata Krishna, Dec 2025
ATL - SDF
Read more Delta reviews

Lady Pilot was perfect in every way wheels up to wheels down communication, professionalism, excellent on time departure and on time arrival, excellent communication! Fantastic job with Superb attitude!!

The food is terrible. The staff is wonderful. Comfort is good.

Left on time, a bit delayed due to headwinds most of the trip.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Getting to the flight was arduous and lengthy. The flight itself was good but the food option wasn’t a good selection. I need to do a Kosher option on my return. Flight crew were nice

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Staff was exceptional! Everyone was kind, professional and friendly making the trip very pleasant. Thank you!

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

horrible service, food was an embarrassment, no charging for cellphones, stay away

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

Good flight, boarding ok and crew very nice. Flight was not full so I was able to be very comfortable. Blanket and pillow provided with was good as it was very cold during the flight . Food was very good(small snack sandwich and an excellent piece of orange cake). Overall good flight, no complaints.

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

we were missing our luggage, trying to find someone to have any empathy was pretty much not happening....

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

Horrible the worst airlines I have ever flown. Cancelled flight with no choices and when contacted them they were not helpful

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Not great experience - we were super late boarding due to issues with aircraft. Then when we finally all got onboard and seated and they started taxiing out to the runway they just stopped then turned around and went back to the airport. Apparently the crew “ran out of time” to legally fly us. They mentioned that they were about 2 minutes away from taking off. I understand the rules and safety but kinda wonder why they would have bothered boarding us in the first place? Had to go all the way back and de plane and then wait in a HUGE line to get a hotel (this is somewhere around 2:30am) finally got to hotel by Uber (no shuttle after 20min so gave up) and they ended up putting us all back on the same aircraft at 10am next morning so got about 2.5 hours sleep. They did give us. $250 credit, but it was a São Paulo Brazil flight out of Dulles. The flight and everything was fine.

Starlink wifi on the Embraer E175 is an excellent experience. I was able to connect and work from IAD all the way to approach into BTV.

7 hours delayed due to operational issues on United’s end. Basically laziness.

Short flight but an "eager to help" crew made the journey more enjoyable!

During booking, I kept trying submitting my payment from the Mexican website and it didn't work. After I had the idea to change it to the Canadian website, it worked but I had to be charged the equivalent of 50 CAD more. I received the clear instruction that I would only be able to check-in at the airport and that it was impossible to select a seat 24 hours before departure, that I had to pay 144 CAD to do so, although not only was I able to check-in 24 hours before departure, but I could have selected my seats for free then. All in all, I almost threw $200 out the window due to misleading information. Besides, the app kept crashing, the information to get to the gate on the app was inaccurate, my gate was switched and I was only informed once in the air (luckily I had noticed the departure pannel), I was not addressed in my language beforehand and even if I tried I was immediately answered in English (which meant the crew understood but didn't want to answer accordingly), there was only one snack & beverage service on my medium haul flight and no beverage service on my short haul flight. To be fair, the planes were comfortable, the crew apart from the language issue was helpful, dynamic and engaging, the plane was clean and the directions were clear and direct. United has a lot of potential to be one of my favourite airlines, but the devil is in the details and a lot of them missed the target.

Better WiFi. I cannot understand that in 2025, United is so behind on a technology that is now a necessity and still painfully unreliable, slow and keeps disconnecting.

Great service on board. Boarding a bit slow due to process. Food was pretty average.

Very small cramped plane for an international flight. Everything else was good, but it was maybe the smallest comfort-wise I've ever been on for longer than 3-4 hours and the trip was 7.5

Flight was delayed 3 hours. No food and drink vouchers was provided. They offered a mini pretzel bag and water .

Staff was rude. Didn’t give water for 2 hours. Worst service

it was fine, decent flight... dont get food besides cookies or pretzels so not sure why you ask about food. same for entertainment..

I got sick nothing contagious but distressing and the care I received by Kayla? Keighly the flight attendant will be memorable for ever. Thank You

I got sick nothing contagious but distressing enough and the care I received on the flight was astounding.

Waaay too small plane. They also need to up the size of the overhead bins. I would love to keep me 3k with of camera equipment in my hard case baggahe instead of it being thrown into the belly of the plane

Attendants were pleasant and the flight was smooth and relaxed.

A little late at the start but all worked out well.

It was fine. No drinks nor snacks offered though. I thought that was unusual.

I liked the humor of the captain and crew on the flight from Flagstaff to Dallas. They were humorous.

AA delayed the flight for 3 hours and 50 minutes, but delayed the last 2 hours, 30 minutes at a time, so if we knew before, could have stayed at home and worked instead of being at the airport wasting time... The plane's crew was excellent, not their fault.

After arriving in Dallas, the aircraft taxied for an unusually long time and was unable to park at the gate, which caused a significant delay and made me miss my connecting flight. I then had to wait in a very long line to be rebooked, and I was told that no hotel or meal accommodations would be provided. What is even more unacceptable is that my luggage was mishandled and has still not been located. My suitcase contains important medications that I urgently need, and I have been unable to access them due to the airline’s mishandling. This situation has caused me considerable stress and inconvenience, and I need this issue to be resolved immediately.

Everything you need to know for your flight to South America

Information on your arrival and departure airports