$739 Find Cheap Flights from Wilmington to Panama - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Price, demand and travel trends for Wilmington to Panama flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

What are the cheapest fares from Wilmington to Panama right now?

The cheapest fare from Wilmington to Panama in the last week was $739 round-trip, to Panama City Tocumen Intl (PTY).

Which airport in Panama is the cheapest to fly to from Wilmington?

All flights from Wilmington to Panama arrive at Panama City Tocumen Intl (PTY). On average, round-trip fares are around $646.

What’s the cheapest day to fly from Wilmington to Panama?

Tuesday tends to be the cheapest day to fly from Wilmington to Panama, while Friday is the most expensive. Fares run about 50% higher that day, based on the past 12 months of KAYAK data.

Key details for Wilmington to Panama flights

Low season

July

Cheapest flight

$739
Beat the crowds with an average 67% drop in travelers.
The most popular month to fly with an average 11% increase in travelers.
Round-trip flight from Wilmington to Panama City

Your Wilmington to Panama flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • Is now a good time to book a flight from Wilmington to Panama?

    Fares from Wilmington to Panama are above average right now, but good deals can still pop up. A round-trip fare under $571 is considered a good deal, so keep an eye on prices. You can also set a Price Alert and KAYAK will monitor flights for you.

  • How much should I budget for a flight from Wilmington to Panama?

    Over the past 12 months, round-trip fares from Wilmington to Panama have ranged from $571 to $708.

  • What airlines fly nonstop from Wilmington to Panama?

    Based on the flight schedule for the next 3 months, no airline regularly operates nonstop flights from Wilmington to Panama. One-stop options include Delta and American Airlines.

  • Which cabin classes are available on flights from Wilmington to Panama?

    On flights from Wilmington to Panama you can book Economy Class or Business Class.

  • What are some popular landmarks in Panama?

    KAYAK travelers' favorite landmarks in Panama include:

    • ATLAPA Conventions Center
    • Panama Old Cathedral
    • Veneto Casino
    • Ancon Hill

Your guide to booking Wilmington to Panama flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your travel dates are flexible, book your trip for June when flights are typically cheapest and avoid July when prices are at their highest.
  • Flying on Tuesday is usually the cheapest. Flights on Friday cost about 50% more on average, so being flexible with your travel dates could help you save.
  • Start your trip in Panama City, which is the most popular destination in Panama. From there, it's easy to continue on to other popular destinations such as Bocas del Toro, Río Hato and Boquete.

Reviews of the top airline flying from Wilmington to Panama

 
Need help choosing which airline to fly with from Wilmington to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.0
American AirlinesOverall score based on 12225 reviews
7.9Crew
6.4Food
6.8Entertainment
7.2Comfort
7.4Boarding
Airline reviews

The wifi was broken. The temperature on the plane was quite warm, and my air vent didn't seem to blow anything but warm air. The flight attendants were nice.

8.0 ExcellentJennifer, Nov 2026
Read more American Airlines reviews

The wifi was broken. The temperature on the plane was quite warm, and my air vent didn't seem to blow anything but warm air. The flight attendants were nice.

It was unfortunate that the plane had mechanical issues and delayed our flight, but I am glad we made it safely! On the first American flight from Charlotte to Phoenix, they changed the gate without getting a notification, and I had to make a mad dash!

I didn't like anything about this flight. The only reason anyone drinks Jack is because you ran out of Woodford. You should know to stock more Woodford. When you wait of first class hand and foot from the minute they get on the plane 5 feet from me but then start service from the rear of the plane so main cabin plus gets the scraps, that's how you get people to stop flying your airline.

We were delayed a long time. We waited for “catering”. We didn’t get any food or accommodation for our wait. It made us land well after dinner time at our destination.

Had to wait for a gate for a long time, then waited on the run way for a long time before leaving. The actual flights part was good.

I had a positive experience on American. I'm blind and traveling with a guide dog and the flight attendants were so kind, friendly, and helpful towards us. They checked in on us during the flight and they made us feel comfortable and welcomed. There was an hour delay before depature, but overall the flight was a smooth ride. I appreciate that there were no issues on this long flight back home.

Flight was delayed. Staff at the gate effectively and proactively communicated about the delay.

It was late, then the bathroom was inoperable plus it was very hot as well. Plane was very old

Overall, I had a great flight on American Airlines. The only compliant that I have is that my gate changed 30 minutes before boarding the flight. This was annoying because I had a connection in Charlotte and it's a very big airport.

Our flight was delayed 45 minutes and we missed our connection, while we were able to get a flight the following day the voucher for food did not work.

More options for your flight from Wilmington to Panama

Complete your trip to Panama with a hotel stay or car rental