BUF - DSM

$178 Find Cheap Flights from Buffalo to Des Moines - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Buffalo to Des Moines departing on 7/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Buffalo to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Buffalo to Des Moines, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$290
Typical prices: $646-$327
American Airlines
Wed 9/23Thu 9/24
BUF - DSM • 1 stop
Cheapest one-way
$178
Typical prices: $211-$226
Delta
Sat 7/4
BUF - DSM • 1 stop
Top airlines
Cheapest • from $290 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Buffalo and Des Moines. You'll need at least 1 connection.
Insights
Insights
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Insights
Top layover airports
Cheapest • Avg $475 (round-trip)
Shortest trip • 4h 10m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 100% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Des Moines!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Buffalo to Des Moines (BUF-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Buffalo to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Buffalo to Des Moines

Wed, Sep 23 - Thu, Sep 24
American Airlines Logo
6:10 am - 12:31 pm
BUF
-
DSM
7h 21m
1 stop
American Airlines Logo
6:00 am - 2:26 pm
DSM
-
BUF
7h 26m
1 stop
$290American Airlines
Wed, Sep 23 - Thu, Sep 24
American Airlines Logo
5:18 pm - 12:04 am
BUF
-
DSM
7h 46m
2 stops
American Airlines Logo
6:00 am - 2:26 pm
DSM
-
BUF
7h 26m
1 stop
$295American Airlines
Sun, Oct 4 - Wed, Oct 7
United Airlines Logo
7:00 am - 10:31 am
BUF
-
DSM
4h 31m
1 stop
United Airlines Logo
1:24 pm - 8:47 pm
DSM
-
BUF
6h 23m
1 stop
$335United Airlines
Wed, Sep 23 - Thu, Sep 24
American Airlines Logo
6:10 am - 12:31 pm
BUF
-
DSM
7h 21m
1 stop
American Airlines Logo
6:00 am - 2:26 pm
DSM
-
BUF
7h 26m
1 stop
$336American Airlines
Wed, Sep 23 - Thu, Sep 24
American Airlines Logo
11:48 am - 7:21 pm
BUF
-
DSM
8h 33m
2 stops
American Airlines Logo
6:00 am - 2:26 pm
DSM
-
BUF
7h 26m
1 stop
$341American Airlines
Tue, Sep 1 - Wed, Sep 2
United Airlines Logo
10:30 am - 2:16 pm
BUF
-
DSM
4h 46m
1 stop
United Airlines Logo
11:32 am - 4:56 pm
DSM
-
BUF
4h 24m
1 stop
$343United Airlines
Tue, Sep 1 - Wed, Sep 2
United Airlines Logo
10:30 am - 8:26 pm
BUF
-
DSM
10h 56m
2 stops
United Airlines Logo
11:32 am - 4:56 pm
DSM
-
BUF
4h 24m
1 stop
$348United Airlines
Sun, Oct 4 - Wed, Oct 7
Southwest Logo
5:30 am - 3:00 pm
BUF
-
DSM
10h 30m
2 stops
Southwest Logo
5:35 am - 10:30 am
DSM
-
BUF
3h 55m
1 stop
$351Southwest
Tue, Oct 6 - Wed, Oct 7
United Airlines Logo
7:00 am - 10:31 am
BUF
-
DSM
4h 31m
1 stop
United Airlines Logo
1:24 pm - 8:47 pm
DSM
-
BUF
6h 23m
1 stop
$370United Airlines
Sun, Oct 4 - Wed, Oct 7
American Airlines Logo
7:59 am - 1:59 pm
BUF
-
DSM
7h 00m
1 stop
American Airlines Logo
3:53 pm - 11:26 pm
DSM
-
BUF
6h 33m
1 stop
$372American Airlines
Booking Insights

KAYAK's insights & trends for Buffalo to Des Moines flights

Get data-powered insights and trends into flights from Buffalo to Des Moines to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Buffalo to Des Moines?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Buffalo to Des Moines departing in September.

What is the cheapest month to fly from Buffalo to Des Moines?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Buffalo to Des Moines, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Buffalo to Des Moines is January, where tickets cost $0 (return) on average. On the other hand, the most expensive months are March and August, where the average cost of round-trip tickets is $699 and $504 respectively.

Good to know

Low seasonApril
Cheapest flight$178
Best time to beat the crowds with an average 21% drop in price.
Most popular time to fly with an average 10% increase in price.
Flight from Buffalo to Des Moines

When to book flights from Buffalo to Des Moines

Are your dates flexible? Find out the best times to travel from Buffalo to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Buffalo to Des Moines

  • What is the cheapest flight from Buffalo to Des Moines?

    In the last 5 days, the lowest price for a flight from Buffalo to Des Moines was $178 for a one-way ticket and $290 for a round-trip.

  • Do I need a passport to fly between Buffalo and Des Moines?

    No, a passport isn't needed to fly from Buffalo to Des Moines. However, local authorities might ask for an official ID.

  • Which airports will I be using when flying from Buffalo to Des Moines?

    Buffalo and Des Moines are both served by 1 main airport. You will leave Buffalo from Buffalo and will be arriving at Des Moines.

  • Which aircraft models fly most regularly from Buffalo to Des Moines?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Buffalo to Des Moines?

    SkyTeam is the only airline alliance operating flights between Buffalo and Des Moines.

  • How does KAYAK find such low prices on flights from Buffalo to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Buffalo to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Buffalo to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from Buffalo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Buffalo to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to Buffalo with another airline. Booking your flights between Buffalo and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Buffalo to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from Buffalo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Buffalo to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from Buffalo to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Buffalo to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8395 reviews
7.8Entertainment
7.8Comfort
8.5Crew
7.2Food
8.1Boarding
Airline reviews

On time! There were plenty of airport employees who were able to keep us moving in the right direction. The crew on the plane were professional.

8.0 ExcellentAnonymous, Jun 2026
JFK - ATL
Read more Delta reviews

On time! There were plenty of airport employees who were able to keep us moving in the right direction. The crew on the plane were professional.

I continue to be satisfied with Delta’s excellent service out of LGA. The digit id works well and gets me through security in no time. Whenever possible, I choose Delta.

Was revoked with Jet Blue due to delay from Kenya Air

WiFi didn’t work. Flight delayed 3 hours Crew members were illiterate Seat lean back did not work.

Transparency from pilots, quick boarding and exiting the plane, staff greeted to each and everyone,

WiFi didn’t work most of the time. The usb chargers would work only occasionally for 5 mins and wouldn’t charge after that. Had to keep trying repeatedly at each of the seats in the row.

The crew bent over backwards to thank us for flying and make us comfortable. The food service was quick and efficient. The Captain communicated and said goodbye and thank you as we departed. They really stood out!

Flight delayed. Air broken. Cabin was hot enough to pass out. Delta shuttle’s becoming worse and worse.

my mom urmila patel needed a wheelchair which was not available on the curbside. she needed to walk almost 50 meters inside (at the risk of falling) and then had to wait in line to get a wheelchair (this is not ok). Once obtained she had to seat in it for 30-45 minutes for someone to take her in thru the checkin process (which was fairly smooth and easy). the lady who helped her with her checkin process was very courteous and helpful

This was the worse experience. They delayed our flight twice and we still had to find another flight to get home sooner which was alos delayed. Also, the flight attendant named Ginny on DL9890 leaving at 4:13pm on 3/23/26 was extremely rude.

Everything you need to know for your flight from Buffalo to Des Moines

Information on your arrival and departure airports