BUF - DSM

$284 Find Cheap Flights from Buffalo to Des Moines - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$405
Typical prices: $406-$549
United Airlines
Sat 10/20Sun 10/21
BUF - DSM • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Buffalo and Des Moines. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
April
Cheapest • 21% price drop
July
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Detroit Metropolitan Wayne County (DTW)
Cheapest • Avg $506 (round-trip)
Chicago Midway (MDW)
Shortest trip • 4h 06m (one-way)
Insights
Insights
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We hope you love your trip to Des Moines!
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Flight Deals

Cheap Flights from Buffalo to Des Moines (BUF-DSM)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Buffalo to Des Moines

Tue, Oct 20 - Wed, Oct 21
United Airlines Logo
7:00 am - 10:31 amBUF  Buffalo-DSM Des Moines
4h 31m1 stop Chicago O'Hare Intl
United Airlines Logo
1:24 pm - 8:47 pmDSM  Des Moines-BUF Buffalo
6h 23m1 stop Chicago O'Hare Intl
$405United Airlines
Tue, Oct 20 - Wed, Oct 21
United Airlines Logo
10:46 am - 9:01 pmBUF  Buffalo-DSM Des Moines
11h 15m2 stops Chicago O'Hare Intl Denver Intl
United Airlines Logo
11:27 am - 4:43 pmDSM  Des Moines-BUF Buffalo
4h 16m1 stop Chicago O'Hare Intl
$410United Airlines
Tue, Oct 20 - Wed, Oct 21
United Airlines Logo
10:46 am - 9:01 pmBUF  Buffalo-DSM Des Moines
11h 15m2 stops Chicago O'Hare Intl Denver Intl
United Airlines Logo
9:15 am - 11:11 pmDSM  Des Moines-BUF Buffalo
12h 56m2 stops Denver Intl Newark
$415United Airlines
Tue, Oct 20 - Wed, Oct 21
United Airlines Logo
7:00 am - 10:31 amBUF  Buffalo-DSM Des Moines
4h 31m1 stop Chicago O'Hare Intl
United Airlines Logo
1:24 pm - 8:47 pmDSM  Des Moines-BUF Buffalo
6h 23m1 stop Chicago O'Hare Intl
$467United Airlines
Sat, Sep 26 - Wed, Sep 30
American Airlines Logo
6:10 am - 12:31 pmBUF  Buffalo-DSM Des Moines
7h 21m1 stop Philadelphia
American Airlines Logo
8:03 am - 5:28 pmDSM  Des Moines-BUF Buffalo
8h 25m2 stops Charlotte Douglas New York LaGuardia
$502American Airlines
Sat, Sep 26 - Wed, Sep 30
American Airlines Logo
7:00 am - 1:59 pmBUF  Buffalo-DSM Des Moines
7h 59m2 stops New York LaGuardia Chicago O'Hare Intl
American Airlines Logo
8:03 am - 5:28 pmDSM  Des Moines-BUF Buffalo
8h 25m2 stops Charlotte Douglas New York LaGuardia
$507American Airlines
Fri, Sep 25 - Tue, Sep 29
American Airlines Logo
5:18 pm - 9:36 pmBUF  Buffalo-DSM Des Moines
5h 18m1 stop Philadelphia
American Airlines Logo
1:30 pm - 9:47 pmDSM  Des Moines-BUF Buffalo
7h 17m1 stop Charlotte Douglas
$515American Airlines
Fri, Sep 25 - Mon, Sep 28
Delta Logo
12:02 pm - 5:19 pmBUF  Buffalo-DSM Des Moines
6h 17m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:00 am - 11:22 amDSM  Des Moines-BUF Buffalo
4h 22m1 stop Detroit Metropolitan Wayne County
$517Delta
Fri, Sep 25 - Tue, Sep 29
Delta Logo
12:02 pm - 5:19 pmBUF  Buffalo-DSM Des Moines
6h 17m1 stop Detroit Metropolitan Wayne County
Delta Logo
5:35 pm - 11:53 pmDSM  Des Moines-BUF Buffalo
5h 18m1 stop Detroit Metropolitan Wayne County
$517Delta
Fri, Sep 25 - Wed, Sep 30
Delta Logo
6:20 am - 9:38 amBUF  Buffalo-DSM Des Moines
4h 18m1 stop Detroit Metropolitan Wayne County
Delta Logo
10:59 am - 6:23 pmDSM  Des Moines-BUF Buffalo
6h 24m1 stop Minneapolis St Paul
$517Delta
Booking Insights

Price, demand and travel trends for Buffalo to Des Moines flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Buffalo to Des Moines with more confidence.

How much is a round-trip flight from Buffalo to Des Moines?

Round-trip flights from Buffalo to Des Moines start at $405. Prices are below average for this route right now, with typical round-trip fares ranging from $406 to $549. The lowest price found in the past 5 days was $405 on United Airlines.

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Key details for Buffalo to Des Moines flights

Low season

October
Best time to beat the crowds but there is an average 34% increase in price.
Most popular time to fly with an average 23% increase in price.

When to book flights from Buffalo to Des Moines

Are your dates flexible? Find out the best times to travel from Buffalo to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Buffalo to Des Moines flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Buffalo to Des Moines?

    Flights from Buffalo to Des Moines usually depart from Buffalo (BUF) and arrive at Des Moines (DSM).

  • What cabin classes can I book on flights from Buffalo to Des Moines?

    Only Economy Class is available on flights from Buffalo to Des Moines.

  • Which airports do connecting flights from Buffalo to Des Moines pass through?

    One-stop flights from Buffalo to Des Moines most commonly connect through:

    • Chicago O'Hare Intl (ORD) - 69% of one-stop connections
    • Detroit Metropolitan Wayne County (DTW) - 21% of one-stop connections
    • Chicago Midway (MDW) - 10% of one-stop connections

    Chicago O'Hare Intl (ORD) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Buffalo to Des Moines?

    Yes. Being flexible with your travel dates can save you up to 56% on the Buffalo to Des Moines route. Tuesday is the cheapest departure day at $348 round-trip on average, while Sunday is the most expensive at $776, a difference of $428. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in Des Moines?

    Some of the most popular sights in Des Moines are Iowa Events Center, UnityPoint Health - Des Moines and Des Moines Civic Center. These are among the most viewed places in Des Moines on KAYAK.

  • How long is a flight from Buffalo to Des Moines?

    A nonstop flight from Buffalo to Des Moines takes 0h 00m, covering 768 miles.

  • Do I need a passport to fly from Buffalo to Des Moines?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Buffalo to Des Moines changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $405 to $1,338. That means the highest observed fare was about 3x higher than the lowest one.

  • How much time can I save by choosing a different layover airport from Buffalo to Des Moines?

    Flying via Chicago Midway (MDW) gives the shortest average 1-stop total travel time at 4h 06m, compared with 4h 17m via Detroit Metropolitan Wayne County (DTW) and 4h 42m via Chicago O'Hare Intl (ORD).

  • What is the time difference between Buffalo and Des Moines?

    Des Moines is 1 hour behind Buffalo (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Des Moines Airport (DSM)?

    Des Moines Airport (DSM) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:
    • Hertz
    • Payless
    • Budget
    • Alamo
    • Avis

  • How much should I expect to pay for a Buffalo to Des Moines flight?

    Round-trip flights from Buffalo to Des Moines range from $406 to $549, with an average of $458 over the past 12 months. Anything below $406 counts as a good deal.

Your guide to booking Buffalo to Des Moines flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Tuesday departure instead of Sunday. On this route, Tuesday flights average $348 - about $428 less than Sunday (55% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Buffalo to Des Moines trip for April. Fares historically average $364 round-trip in that month - typically $445 less than the most expensive month, which is September (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Des Moines Airport.
    - Days Inn & Suites by Wyndham Des Moines Airport
    - Quality Inn & Suites Des Moines Airport
    - Holiday Inn Des Moines-Airport/Conf Center By IHG

More options for your flight from Buffalo to Des Moines

Complete your trip to Des Moines with a hotel stay or car rental

Car rentals in Des Moines
Hotels in Des Moines
Vacations in Des Moines