DSM - BUF

$162 Find Cheap Flights from Des Moines to Buffalo - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Buffalo departing on 7/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Buffalo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Buffalo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Buffalo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$355
Typical prices: $434-$373
American Airlines
Sat 7/4Sat 7/4
DSM - BUF • 1 stop
Cheapest one-way
$162
Typical prices: $192-$273
Multiple Airlines
Sun 7/5
DSM - BUF • 2 stops
Top airlines
Cheapest • from $291 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Buffalo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $315 (round-trip)
Shortest trip • 3h 55m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 100% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Buffalo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Buffalo (DSM-BUF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Buffalo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Buffalo

Sat, Jul 4 - Sat, Jul 4
American Airlines Logo
6:14 am - 12:22 pm
DSM
-
BUF
5h 08m
1 stop
American Airlines Logo
5:20 pm - 10:07 pm
BUF
-
DSM
5h 47m
1 stop
$355American Airlines
Thu, Aug 27 - Sun, Aug 30
American Airlines Logo
5:41 am - 2:26 pm
DSM
-
BUF
7h 45m
1 stop
American Airlines Logo
5:19 pm - 10:06 pm
BUF
-
DSM
5h 47m
1 stop
$372American Airlines
Wed, Jul 1 - Mon, Jul 6
American Airlines Logo
7:09 pm - 12:38 am
DSM
-
BUF
4h 29m
1 stop
American Airlines Logo
6:32 am - 1:05 pm
BUF
-
DSM
7h 33m
1 stop
$381American Airlines
Sat, Jun 27 - Wed, Jul 1
Multiple Airlines Logo
5:06 pm - 7:12 pm
DSM
-
BUF
25h 06m
1 stop
Multiple Airlines Logo
2:50 pm - 9:27 pm
BUF
-
DSM
31h 37m
2 stops
$389Multiple Airlines
Wed, Jul 1 - Mon, Jul 6
Delta Logo
10:54 am - 6:27 pm
DSM
-
BUF
6h 33m
1 stop
Delta Logo
6:29 am - 9:44 am
BUF
-
DSM
4h 15m
1 stop
$391Delta
Thu, Aug 27 - Sun, Aug 30
Multiple Airlines Logo
1:55 pm - 1:55 pm
DSM
-
BUF
23h 00m
2 stops
Multiple Airlines Logo
8:57 pm - 4:38 pm
BUF
-
DSM
20h 41m
1 stop
$395Multiple Airlines
Sat, Aug 1 - Sat, Aug 8
Delta Logo
5:32 pm - 10:45 pm
DSM
-
BUF
4h 13m
1 stop
Delta Logo
3:54 pm - 8:39 pm
BUF
-
DSM
5h 45m
1 stop
$407Delta
Thu, Jul 2 - Fri, Jul 3
American Airlines Logo
1:41 pm - 10:51 pm
DSM
-
BUF
8h 10m
1 stop
American Airlines Logo
8:27 am - 1:04 pm
BUF
-
DSM
5h 37m
1 stop
$409American Airlines
Tue, Jul 21 - Thu, Jul 23
American Airlines Logo
5:00 am - 2:19 pm
DSM
-
BUF
8h 19m
2 stops
American Airlines Logo
8:08 am - 1:05 pm
BUF
-
DSM
5h 57m
1 stop
$412American Airlines
Tue, Jun 30 - Mon, Jul 6
American Airlines Logo
1:51 pm - 11:56 pm
DSM
-
BUF
9h 05m
2 stops
American Airlines Logo
6:32 am - 1:05 pm
BUF
-
DSM
7h 33m
1 stop
$414American Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Buffalo flights

Get data-powered insights and trends into flights from Des Moines to Buffalo to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Des Moines to Buffalo?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Buffalo, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Buffalo is November, where tickets cost $0 (return) on average. On the other hand, the most expensive months are March and May, where the average cost of round-trip tickets is $736 and $538 respectively.

Good to know

Low seasonOctober
Cheapest flight$162
Best time to beat the crowds with an average 41% drop in price.
Most popular time to fly and prices are also 28% lower on average.
Flight from Des Moines to Buffalo

When to book flights from Des Moines to Buffalo

Are your dates flexible? Find out the best times to travel from Des Moines to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Buffalo

  • What is the cheapest flight from Des Moines to Buffalo?

    In the last 5 days, the lowest price for a flight from Des Moines to Buffalo was $162 for a one-way ticket and $291 for a round-trip.

  • Do I need a passport to fly between Des Moines and Buffalo?

    No, a passport isn't needed to fly from Des Moines to Buffalo. However, local authorities might ask for an official ID.

  • Which aircraft models fly most regularly from Des Moines to Buffalo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Buffalo?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between Des Moines and Buffalo, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Buffalo, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Buffalo are Delta and United Airlines. With an average price for the route of $332 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $430 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Des Moines to Buffalo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Buffalo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Buffalo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Buffalo from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Buffalo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Buffalo with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and BUF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Buffalo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Buffalo from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Des Moines to Buffalo

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Buffalo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Buffalo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8396 reviews
7.2Food
8.1Boarding
7.8Comfort
7.8Entertainment
8.5Crew
Airline reviews

Left /arrived on time. Decent seat space. Like the wifi/plugs and entertainment. Windows and tray table were kinda gross. Attendants didn't start snack service til 40mins before landing. Two rows before us, captain came on to say there's turbulence and recalled staff to seats. So, no drink/snack. Later, attendants didn't stop to see if we had trash nor even look our way. Felt invisible! Almost all pilot announcements were not only unintelligible, but so quiet. We had no idea what she said.

8.0 ExcellentAnonymous, Jun 2026
TPA - LGA
Read more Delta reviews

Left /arrived on time. Decent seat space. Like the wifi/plugs and entertainment. Windows and tray table were kinda gross. Attendants didn't start snack service til 40mins before landing. Two rows before us, captain came on to say there's turbulence and recalled staff to seats. So, no drink/snack. Later, attendants didn't stop to see if we had trash nor even look our way. Felt invisible! Almost all pilot announcements were not only unintelligible, but so quiet. We had no idea what she said.

Gate agent was unhelpful for handicapped boarding. Flight attendant seemed untrained.

Free & relatively fast Wi-Fi. Would've liked a wider drink selection.

Delta does a great job with entertainment and free wifi. I can still be in touch with my colleagues while in the air.

Very easy to use and convenient, you can perform any action within the same portal

The baggage belt was not updated on the Delta App and was displayed on the wrong belt board. Was not expecting this to happen.

Landed without a gate ready. Plane is extremely old and dirty.

Pilots lied about waiting on “paperwork”. Sat in the plane for over an hour, waiting on some papers to be printed according to the pilot and then all of a sudden he says good news maintenance is finally on their way. Maybe they can fix it before we get our paperwork. Ended up missing my connection in LaGuardia and as a result, had a fly home to Lexington instead of the Louisville airport. Then paid $100 to uber to Louisville since it was midnight by the time I got in. I wish they would just be transparent with passengers sometimes and not try to beat around the bush on why things are delayed.

The flight was delayed 90 minutes The Gate was wrong The Restroom on Aircraft was not clean There was a half used water bottle in my seat

Too many people are taking up space in the overhead bins with their extra piece of luggage. Since they cannot fit their backpacks or extra luggage piece under the seat in front of them, they store it in the overheads and thus taking up room for other passengers. It wasn’t only one or two persons; more like 12 or 13 passengers.

Packed flight, which makes it tough on crew and boarding staff (and the customers of course). But this was great boarding, clear instructions, etc. Traveling on the weekends are always fraught with danger as you have families and less frequent flyers thus more confusion. But this flight went as planned.

Destroyed my suitcase. Tired of talking about it. Cancelling my unite mileage plus account.

Read the fine print. This was my flight home. I booked my flight for the quickest way home. Had a carry-on and a personal item. Same as my outbound flight. Apparently I needed to pre-pay extra for my carry-on. When I checked in, I was told that I had to check it. I said I’ll pay for it, and was told that this wasn’t an option anymore. They said I still had to pay $50 to check my carry-on. I told them I’ll pay whatever to just carry it in as intended. I was not allowed, so eventually I paid $50 to check my carry-on under a plane that was half full, with overhead compartments that were even less full. My white carry-on suitcase was practically destroyed getting from Idaho falls to Denver to Orange County. The low price air fair was a bait and switch. Got me to the gate, made me pay extra, then didn’t even allow me to pay for a carry on. Not to mention that I paid the $8 for WiFi that didn’t work. All to get my suitcase destroyed. I don’t think I’m going to even keep my Untied mileage plus membership and card. Apparently, membership does not have its privileges for this one.

The flight was delayed, they didn’t even have water for the toilets or for drinks

Even through the flight was delayed due to storms near IAH The flight was great! The crew was so hospitable and professional

I flew from Santa Fe to Denver to catch a flight to London and the transfer of my luggage on arrival at Denver to the London flight worked perfectly. The crew on the ground and on board for the London flight were so friendly and efficient.

Boarded early; and arrived home 40 mins early. After a long flight, it’s nice to be back home early. These flights have no amenities; no snacks. So need to bring your own

Boarded early, left early, arrived 40 mins early! A win win for me!

New plane was lovely. Crew customer service is always lax but expected. Kraft on time and arrived safely.

These airplanes should be illegal. The seats are two tight, it is a safety issue. Wheelchair support was ridiculously slow. We almost missed our flight.

Our flight from JFK to Madrid was delayed. We had to go from one side of the Madrid airport (Terminal 4s to the far end of terminal 4 - Gate K98) to our gate in less than 30 minutes. Put passport control and security/baggage check and that’s very hard unless you’re Usain Bolt. I called Iberia Airlines and the telephone customer service told me that I was going to have to pay to re-book. Luckily the help desk in the airport (who was dealing with dozens of people from the same JFK-Madrid flight) did not charge us extra to reschedule to a flight 8 hours later. They also gave us a voucher for breakfast and lunch. Glad the actual person at the airport had some actual sense.

Our flight was repeatedly delayed for maintenance problems: scheduled for 9.30am, eventually delayed to 7pm! Very very inconvenient! AA should have provided a substitute plane much earlier.. On the other hand, Customer Service crew in Charlotte helped us to reach NY (LGA) by late afternoon. Thank you Patricia!! The actual flight was quick and very comfortable. As always a. excellent, professional crew. [no food on a a short hop).

The flight was peaceful, just s slight turbulence, pilots and crews were all nice and made a great job! Arrived safely in the Philippines. Thank you ya’ll!

Terrible steward... Plane was quite empty... I asked to move "back" in the plane and the steward said no... Unnecessary power trip of mediocre people.

Boarding gate at LAX was too crowded—two gates next to one another

It was really a terrific experience both going and returning on AA. Staff and crew were professional.

This short sector between Miami and JFK was undertaken purely for business purposes, with efficiency as the primary objective rather than a full inflight experience. Overall, the journey met its intended purpose; however, the ground experience at Miami stood out significantly. During check-in, I was unable to link my frequent flyer details from Qatar Airways (oneworld alliance) through either the self-service kiosk or web check-in. The situation was handled exceptionally well by the check-in agent, who demonstrated remarkable ownership. She coordinated across multiple counters, ensured my frequent flyer number was correctly reflected, reissued the boarding pass, and confirmed that mileage accrual would be recognized. Additionally, she ensured the boarding pass reflected priority status, enabling a seamless priority check-in experience without delays. This level of proactive service was both commendable and impactful. Boarding and the inflight experience, operated by American Airlines under a codeshare arrangement, were efficient but largely transactional. While operational delivery was smooth, there was no visible recognition of oneworld frequent flyer status onboard. In comparison to the consistently personalized engagement typically experienced with Qatar Airways, this absence was noticeable—though understandably a potential limitation of codeshare alignment rather than a direct service shortfall. In summary, while the flight itself fulfilled its operational intent, the exceptional professionalism and commitment demonstrated at the Miami check-in counter was the defining highlight of this journey. Greater consistency in elite recognition across partner airlines would further enhance the overall experience.

I almost missed my flight and they helped me out enormously

Flight was fine, but not having WiFi was a major negative

Everything was excellent and I enjoyed myself. Thank for everything

Everything you need to know for your flight from Des Moines to Buffalo

Information on your arrival and departure airports