DSM - BUF

$253 Find Cheap Flights from Des Moines to Buffalo - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$317
Typical prices: $317-$463
Multiple Airlines
Mon 9/10Thu 9/13
DSM - BUF • 2 stops
Cheapest one-way
$253
Typical prices: $209-$313
Delta
Tue 10/2
DSM - BUF • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Buffalo. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
September
Cheapest • 17% price drop
August
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Detroit Metropolitan Wayne County (DTW)
Cheapest • Avg $334 (round-trip)
Chicago Midway (MDW)
Shortest trip • 4h 14m (one-way)
Insights
Insights
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Booking Insights
Flight Deals

Cheap Flights from Des Moines to Buffalo (DSM-BUF)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Buffalo

Thu, Sep 10 - Sun, Sep 13
Multiple Airlines Logo
8:00 am - 12:55 pmDSM  Des Moines-BUF Buffalo
27h 55m2 stops Austin Bergstrom Atlanta Hartsfield-Jackson
Multiple Airlines Logo
12:49 pm - 9:34 amBUF  Buffalo-DSM Des Moines
21h 45m1 stop Orlando
$317Multiple Airlines
Mon, Nov 2 - Mon, Nov 9
Southwest Logo
5:25 am - 10:25 amDSM  Des Moines-BUF Buffalo
4h 00m1 stop Chicago Midway
Southwest Logo
7:10 pm - 11:00 pmBUF  Buffalo-DSM Des Moines
4h 50m1 stop Chicago Midway
$325Southwest
Mon, Sep 14 - Thu, Sep 17
Delta Logo
5:35 pm - 11:53 pmDSM  Des Moines-BUF Buffalo
5h 18m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:20 am - 9:38 amBUF  Buffalo-DSM Des Moines
4h 18m1 stop Detroit Metropolitan Wayne County
$325Delta
Sat, Sep 12 - Thu, Sep 17
Delta Logo
5:35 pm - 10:35 pmDSM  Des Moines-BUF Buffalo
4h 00m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:20 am - 9:38 amBUF  Buffalo-DSM Des Moines
4h 18m1 stop Detroit Metropolitan Wayne County
$325Delta
Sat, Sep 26 - Wed, Sep 30
United Airlines Logo
3:11 pm - 8:47 pmDSM  Des Moines-BUF Buffalo
4h 36m1 stop Chicago O'Hare Intl
United Airlines Logo
5:45 pm - 11:35 pmBUF  Buffalo-DSM Des Moines
6h 50m1 stop Chicago O'Hare Intl
$325United Airlines
Sat, Sep 12 - Sat, Sep 19
Delta Logo
5:35 pm - 10:35 pmDSM  Des Moines-BUF Buffalo
4h 00m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:20 am - 9:38 amBUF  Buffalo-DSM Des Moines
4h 18m1 stop Detroit Metropolitan Wayne County
$325Delta
Mon, Sep 14 - Sat, Sep 19
Delta Logo
5:35 pm - 11:53 pmDSM  Des Moines-BUF Buffalo
5h 18m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:20 am - 9:38 amBUF  Buffalo-DSM Des Moines
4h 18m1 stop Detroit Metropolitan Wayne County
$325Delta
Fri, Sep 11 - Sat, Sep 19
Delta Logo
5:35 pm - 10:35 pmDSM  Des Moines-BUF Buffalo
4h 00m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:20 am - 9:38 amBUF  Buffalo-DSM Des Moines
4h 18m1 stop Detroit Metropolitan Wayne County
$325Delta
Sat, Sep 26 - Wed, Sep 30
American Airlines Logo
2:44 pm - 10:10 pmDSM  Des Moines-BUF Buffalo
6h 26m1 stop Chicago O'Hare Intl
American Airlines Logo
5:18 pm - 12:04 amBUF  Buffalo-DSM Des Moines
7h 46m2 stops Philadelphia Chicago O'Hare Intl
$330American Airlines
Wed, Nov 4 - Fri, Nov 6
American Airlines Logo
7:12 am - 5:26 pmDSM  Des Moines-BUF Buffalo
9h 14m2 stops Chicago O'Hare Intl New York LaGuardia
American Airlines Logo
4:16 pm - 12:14 amBUF  Buffalo-DSM Des Moines
8h 58m2 stops Boston Logan Intl Chicago O'Hare Intl
$376American Airlines
Booking Insights

Price, demand and travel trends for Des Moines to Buffalo flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Des Moines to Buffalo with more confidence.

What's the cheapest day of the week to fly from Des Moines to Buffalo?

Saturday is the cheapest day of the week to fly from Des Moines to Buffalo, it is 18% cheaper than the average day. Sunday is the most expensive day with flight prices 66% higher than average. Based on deals found by KAYAK users in the last 12 months.

Find deals

Key details for Des Moines to Buffalo flights

Low season

February

Cheapest flight

$253
Best time to beat the crowds with an average 11% drop in price.
Most popular time to fly and prices are also 15% lower on average.
Flight from Des Moines to Buffalo

When to book flights from Des Moines to Buffalo

Are your dates flexible? Find out the best times to travel from Des Moines to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Des Moines to Buffalo flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Des Moines to Buffalo?

    Flights from Des Moines to Buffalo usually depart from Des Moines (DSM) and arrive at Buffalo (BUF).

  • What cabin classes can I book on flights from Des Moines to Buffalo?

    Only Economy Class is available on flights from Des Moines to Buffalo.

  • Which airports do connecting flights from Des Moines to Buffalo pass through?

    One-stop flights from Des Moines to Buffalo most commonly connect through:

    • Chicago O'Hare Intl (ORD) - 52% of one-stop connections
    • Detroit Metropolitan Wayne County (DTW) - 39% of one-stop connections
    • Charlotte Douglas (CLT) - 3% of one-stop connections
    • Chicago Midway (MDW) - 3% of one-stop connections

    Chicago O'Hare Intl (ORD) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Des Moines to Buffalo?

    On the Des Moines to Buffalo route, being flexible with your departure day can save you up to 51%. Saturday is the cheapest day at $317 round-trip on average, while Sunday is the most expensive at $636: a $319 difference. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

  • How long is a flight from Des Moines to Buffalo?

    A nonstop flight from Des Moines to Buffalo takes 0h 00m, covering 768 miles.

  • What are the earliest and latest flights from Des Moines to Buffalo?

    These are the earliest and latest flight times available from Des Moines to Buffalo:

    • Earliest: departs at 12:00 am and lands at 12:00 am
    • Latest: departs at 12:00 am and lands at 12:00 am.

    The flight takes about 0h 00m.

  • Do I need a passport to fly from Des Moines to Buffalo?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Des Moines to Buffalo changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $317 to $1,133. That means the highest observed fare was about 4x higher than the lowest one.

  • How are flight prices from Des Moines to Buffalo looking right now?

    One-way fares from Des Moines to Buffalo are currently higher than usual. Average one-way flight prices are about $670, which is 179% above the typical average for this route.

  • How much time can I save by choosing a different layover airport from Des Moines to Buffalo?

    Flying via Chicago Midway (MDW) gives the shortest average 1-stop total travel time at 4h 14m, compared with 4h 25m via Detroit Metropolitan Wayne County (DTW) and 4h 54m via Chicago O'Hare Intl (ORD).

  • What is the time difference between Des Moines and Buffalo?

    Buffalo is 1 hour ahead of Des Moines (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Buffalo Airport (BUF)?

    Buffalo Airport (BUF) hosts 5 major car rental companies, with daily rates starting from around $19 for economy cars. Top options include:
    · Dollar
    · Budget
    · Hertz
    · Alamo
    · Thrifty

  • How much should I expect to pay for a Des Moines to Buffalo flight?

    Round-trip flights from Des Moines to Buffalo range from $317 to $463, with an average of $382 over the past 12 months. Anything below $317 counts as a good deal.

Your guide to booking Des Moines to Buffalo flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Saturday departure instead of Sunday. On this route, Saturday flights average $317 - about $319 less than Sunday (50% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Des Moines to Buffalo trip for September. Fares historically average $317 round-trip in that month - typically $419 less than the most expensive month, which is March (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Buffalo Airport.
    - Aloft Buffalo Airport
    - Comfort Inn and Suites Buffalo Airport
    - TownePlace Suites by Marriott Buffalo Airport

Everything you need to know for your flight from Des Moines to Buffalo

Information on your arrival and departure airports

Des Moines (DSM)
Buffalo (BUF)