Find Deals on Flights from Des Moines to Buffalo (DSM - BUF)

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
Students
under 26
The price shown for each flight will be the average for all passengers including any infants.
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Book cheap flights from Des Moines to Buffalo

(Round-trip)
Depart: Tue Feb 7 2017 Return: Tue Feb 14 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
8:23a
BUF
3:36p
7h 13m
1 stop
BUF
3:10a
DSM
8:52a
5h 42m
1 stop
Depart: Sat Feb 4 2017 Return: Tue Feb 7 2017 Trip spans 4 days
Delta
Delta
DSM
9:30a
BUF
5:07p
7h 37m
1 stop
BUF
6:07a
DSM
12:34p
6h 27m
1 stop
Depart: Fri Feb 10 2017 Return: Mon Feb 13 2017 Trip spans 4 days
Major Airline
Major Airline
DSM
12:00a
BUF
12:32a
0h 32m
1 stop
BUF
12:00a
DSM
2:32a
2h 32m
1 stop
Depart: Thu Feb 23 2017 Return: Sat Feb 25 2017 Trip spans 3 days
United
United
DSM
12:11a
BUF
3:59a
3h 48m
1 stop
BUF
2:00a
DSM
6:35a
4h 35m
1 stop
Depart: Wed Feb 8 2017 Return: Tue Feb 14 2017 Trip spans 7 days
American Airlines
American Airlines
DSM
8:23a
BUF
3:36p
7h 13m
1 stop
BUF
3:10a
DSM
8:52a
5h 42m
1 stop
Depart: Wed Mar 1 2017 Return: Sat Mar 4 2017 Trip spans 4 days
Delta
Delta
DSM
6:50a
BUF
11:02a
4h 12m
1 stop
BUF
1:30a
DSM
8:40a
7h 10m
1 stop
Depart: Tue Feb 14 2017 Return: Tue Feb 28 2017 Trip spans 15 days
American Airlines
American Airlines
DSM
8:23a
BUF
3:36p
7h 13m
1 stop
BUF
3:14a
DSM
8:52a
5h 38m
1 stop
Depart: Mon Feb 27 2017 Return: Wed Mar 1 2017 Trip spans 3 days
Delta
Delta
DSM
12:45p
BUF
5:25p
4h 40m
1 stop
BUF
1:00a
DSM
7:15a
6h 15m
1 stop
Depart: Wed Feb 15 2017 Return: Tue Feb 28 2017 Trip spans 14 days
American Airlines
American Airlines
DSM
10:20a
BUF
3:36p
5h 16m
1 stop
BUF
3:14a
DSM
8:52a
5h 38m
1 stop
Depart: Wed May 31 2017 Return: Sun Jun 4 2017 Trip spans 5 days
United
United
DSM
7:23a
BUF
11:25a
4h 02m
1 stop
BUF
1:50a
DSM
7:20a
5h 30m
1 stop
Depart: Thu Jul 13 2017 Return: Tue Jul 18 2017 Trip spans 6 days
Major Airline
Major Airline
DSM
2:00a
BUF
2:32a
0h 32m
nonstop
BUF
2:00a
DSM
4:32a
2h 32m
nonstop
Depart: Sun Feb 5 2017 Return: Tue Feb 7 2017 Trip spans 3 days
Delta
Delta
DSM
11:00a
BUF
3:47p
4h 47m
1 stop
BUF
1:00a
DSM
7:03a
6h 03m
1 stop
Depart: Tue Feb 21 2017 Return: Tue Feb 28 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
10:20a
BUF
3:36p
5h 16m
1 stop
BUF
3:14a
DSM
8:52a
5h 38m
1 stop
Depart: Mon Feb 20 2017 Return: Wed Feb 22 2017 Trip spans 3 days
Delta
Delta
DSM
1:20a
BUF
5:37a
4h 17m
1 stop
BUF
11:28a
DSM
6:57p
7h 29m
1 stop
Depart: Wed Feb 22 2017 Return: Tue Feb 28 2017 Trip spans 7 days
American Airlines
American Airlines
DSM
8:23a
BUF
3:36p
7h 13m
1 stop
BUF
3:14a
DSM
8:52a
5h 38m
1 stop
Depart: Sun Jul 16 2017 Return: Sun Jul 23 2017 Trip spans 8 days
United
United
DSM
2:25p
BUF
6:48p
4h 23m
1 stop
BUF
3:20a
DSM
7:20a
4h 00m
1 stop
Depart: Tue Feb 28 2017 Return: Tue Mar 7 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
8:23a
BUF
3:36p
7h 13m
1 stop
BUF
3:15a
DSM
8:52a
5h 37m
1 stop
Depart: Fri Mar 17 2017 Return: Mon Mar 20 2017 Trip spans 4 days
United
United
DSM
7:15a
BUF
11:29a
4h 14m
1 stop
BUF
1:15p
DSM
10:53a
21h 38m
1 stop
Depart: Fri Feb 24 2017 Return: Tue Feb 28 2017 Trip spans 5 days
Delta
Delta
DSM
6:50a
BUF
11:02a
4h 12m
1 stop
BUF
1:00a
DSM
7:15a
6h 15m
1 stop
Depart: Sat Feb 11 2017 Return: Tue Feb 14 2017 Trip spans 4 days
American Airlines
American Airlines
DSM
11:00a
BUF
2:55p
3h 55m
1 stop
BUF
3:10a
DSM
8:52a
5h 42m
1 stop
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

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Why aren’t prices accurate 100% of the time?
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Airports
Origin

Des Moines
$301
Destination

Buffalo
$301