Which airports can I use when flying from Des Moines to Buffalo?

Flights from Des Moines to Buffalo usually depart from Des Moines (DSM) and arrive at Buffalo (BUF).

What cabin classes can I book on flights from Des Moines to Buffalo?

Only Economy Class is available on flights from Des Moines to Buffalo.

Which airports do connecting flights from Des Moines to Buffalo pass through?

One-stop flights from Des Moines to Buffalo most commonly connect through: • Chicago O'Hare Intl (ORD) - 62% of one-stop connections • Detroit Metropolitan Wayne County (DTW) - 19% of one-stop connections • Philadelphia (PHL) - 10% of one-stop connections • Charlotte Douglas (CLT) - 5% of one-stop connections

Can I save money by using flexible dates for flights from Des Moines to Buffalo?

Yes. Flexible dates can save you up to 51% on flights from Des Moines to Buffalo. Saturday is the cheapest departure day at $313 round-trip on average, while Sunday is the most expensive at $636, a difference of $323. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

How long is a flight from Des Moines to Buffalo?

A nonstop flight from Des Moines to Buffalo takes 00m, covering 768 miles.

Do I need a passport to fly from Des Moines to Buffalo?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Have flight prices from Des Moines to Buffalo changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $325 to $1,392. That means the highest observed fare was about 4x higher than the lowest one.

How are flight prices from Des Moines to Buffalo looking right now?

One-way fares from Des Moines to Buffalo are currently higher than usual. Average one-way flight prices are about $313, which is 12% above the typical average for this route.

How much time can I save by choosing a different layover airport from Des Moines to Buffalo?

Flying via Chicago Midway (MDW) gives the shortest average 1-stop total travel time at 4h 14m, compared with 4h 36m via Detroit Metropolitan Wayne County (DTW) and 4h 55m via Chicago O'Hare Intl (ORD).

What is the time difference between Des Moines and Buffalo?

Buffalo is 1 hour ahead of Des Moines (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Buffalo Airport (BUF)?

Buffalo Airport (BUF) hosts 5 major car rental companies, with daily rates averaging $81 for economy cars. Top options include: • Dollar • Budget • Hertz • Thrifty • Alamo

How much should I expect to pay for a Des Moines to Buffalo flight?

Round-trip flights from Des Moines to Buffalo range from $341 to $540, with an average of $406 over the past 12 months. Anything below $341 counts as a good deal.

How much is a round-trip flight from Des Moines to Buffalo?

Round-trip flights from Des Moines to Buffalo typically range from $341 to $540. The lowest price found in the past 5 days was $325, on American Airlines.

What's the cheapest day of the week to fly from Des Moines to Buffalo?

Based on deals KAYAK users found in the last 12 months, Saturday is the cheapest day of the week to fly from Des Moines to Buffalo. It’s 23% cheaper than the average day, while Sunday is the most expensive, with prices 56% higher.

Which airline is the cheapest to fly from Des Moines to Buffalo?

American Airlines ($325) and Delta ($325) are the cheapest airlines to fly round-trip from Des Moines to Buffalo according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from Des Moines to Buffalo?

Chicago O'Hare Intl (ORD) is the most popular layover for the Des Moines to Buffalo route. 62% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via ORD.

What is the cheapest layover airport when flying from Des Moines to Buffalo?

Flights via Detroit Metropolitan Wayne County (DTW) offer the most affordable fares, with an average round-trip price of $374. Based on KAYAK data over the past 3 months.

When flying from Des Moines to Buffalo which airport offers the shortest layover?

Chicago Midway (MDW) had the shortest average connection time for Des Moines to Buffalo layovers at 2h 44m over the past 3 months.

$163 CHEAP FLIGHTS from Des Moines to Buffalo (DSM - BUF)

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Cheapest round-trip

$325

Typical prices: $341-$540

American Airlines

Sun 12/9Sun 12/16

DSM - BUF • 1 stop

Cheapest one-way

$163

Typical prices: $223-$338

Delta

Sun 12/2

DSM - BUF • 1 stop

Nonstop flights

Not available

There are currently no direct flights between Des Moines and Buffalo. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

August

Cheapest • 20% price drop

March

Most popular

Good to know

Top layover airports

Detroit Metropolitan Wayne County (DTW)

Cheapest • Avg $374 (round-trip)

Chicago Midway (MDW)

Shortest trip • 4h 14m (one-way)

Insights

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Flight Deals

Cheap Flights from Des Moines to Buffalo (DSM-BUF)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Des Moines to Buffalo

Wed, Dec 9 - Wed, Dec 16

5:24 am - 11:42 amDSM Des Moines-BUF Buffalo

5h 18m1 stop Washington, D.C. Reagan-National

6:49 pm - 12:33 amBUF Buffalo-DSM Des Moines

6h 44m1 stop Chicago O'Hare Intl

$325American Airlines

Wed, Dec 9 - Wed, Dec 16

6:09 am - 11:24 amDSM Des Moines-BUF Buffalo

4h 15m1 stop Detroit Metropolitan Wayne County

6:10 am - 9:50 amBUF Buffalo-DSM Des Moines

4h 40m1 stop Detroit Metropolitan Wayne County

$325Delta

Wed, Dec 9 - Wed, Dec 16

3:25 pm - 8:55 pmDSM Des Moines-BUF Buffalo

4h 30m1 stop Chicago Midway

2:45 pm - 8:50 pmBUF Buffalo-DSM Des Moines

7h 05m1 stop Denver Intl

$325Southwest

Wed, Dec 9 - Wed, Dec 16

6:00 am - 4:30 pmDSM Des Moines-BUF Buffalo

9h 30m2 stops Chicago Midway Baltimore/Washington

8:05 am - 11:25 amBUF Buffalo-DSM Des Moines

4h 20m1 stop Chicago Midway

$330Southwest

Wed, Dec 9 - Wed, Dec 16

5:24 am - 11:42 amDSM Des Moines-BUF Buffalo

5h 18m1 stop Washington, D.C. Reagan-National

4:21 pm - 12:33 amBUF Buffalo-DSM Des Moines

9h 12m2 stops Boston Logan Intl Chicago O'Hare Intl

$330American Airlines

Wed, Dec 9 - Wed, Dec 16

9:23 am - 6:00 pmDSM Des Moines-BUF Buffalo

7h 37m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

4:21 pm - 12:33 amBUF Buffalo-DSM Des Moines

9h 12m2 stops Boston Logan Intl Chicago O'Hare Intl

$335American Airlines

Mon, Dec 14 - Wed, Dec 16

1:23 pm - 10:57 pmDSM Des Moines-BUF Buffalo

8h 34m1 stop Denver Intl

1:53 pm - 5:14 pmBUF Buffalo-DSM Des Moines

4h 21m1 stop Chicago O'Hare Intl

$425United Airlines

Thu, Nov 26 - Mon, Nov 30

5:10 am - 10:25 amDSM Des Moines-BUF Buffalo

4h 15m1 stop Chicago Midway

7:25 pm - 11:35 pmBUF Buffalo-DSM Des Moines

5h 10m1 stop Chicago Midway

$426Southwest

Mon, Dec 14 - Wed, Dec 16

1:15 pm - 11:34 pmDSM Des Moines-BUF Buffalo

9h 19m2 stops Chicago O'Hare Intl Newark

10:30 am - 2:14 pmBUF Buffalo-DSM Des Moines

4h 44m1 stop Chicago O'Hare Intl

$430United Airlines

Thu, Nov 26 - Mon, Nov 30

5:10 am - 10:25 amDSM Des Moines-BUF Buffalo

4h 15m1 stop Chicago Midway

4:30 pm - 11:35 pmBUF Buffalo-DSM Des Moines

8h 05m2 stops Nashville Intl Chicago Midway

$431Southwest

Booking Insights

Price, demand and travel trends for Des Moines to Buffalo flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Des Moines to Buffalo? This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to Buffalo departing in december.
What's the cheapest day of the week to fly from Des Moines to Buffalo?: Based on deals KAYAK users found in the last 12 months, Saturday is the cheapest day of the week to fly from Des Moines to Buffalo. It’s 23% cheaper than the average day, while Sunday is the most expensive, with prices 56% higher.

Find deals

Low season	December
High season	March
Cheapest flight	$163

Beat the crowds with an average 70% drop in travelers.

The most popular month to fly with an average 21% increase in travelers.

One-way flight from Des Moines to Buffalo

When to book flights from Des Moines to Buffalo

Are your dates flexible? Find out the best times to travel from Des Moines to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Des Moines to Buffalo?
Only Economy Class is available on flights from Des Moines to Buffalo.
How long is a flight from Des Moines to Buffalo?
A nonstop flight from Des Moines to Buffalo takes 00m, covering 768 miles.
Do I need a passport to fly from Des Moines to Buffalo?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.
How much should I expect to pay for a Des Moines to Buffalo flight?
Round-trip flights from Des Moines to Buffalo range from $341 to $540, with an average of $406 over the past 12 months. Anything below $341 counts as a good deal.
Have flight prices from Des Moines to Buffalo changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $325 to $1,392. That means the highest observed fare was about 4x higher than the lowest one.
How are flight prices from Des Moines to Buffalo looking right now?
One-way fares from Des Moines to Buffalo are currently higher than usual. Average one-way flight prices are about $313, which is 12% above the typical average for this route.
What car rental options are available at Buffalo Airport (BUF)?
Buffalo Airport (BUF) hosts 5 major car rental companies, with daily rates averaging $81 for economy cars. Top options include:

• Dollar
• Budget
• Hertz
• Thrifty
• Alamo
Which airports can I use when flying from Des Moines to Buffalo?
Flights from Des Moines to Buffalo usually depart from Des Moines (DSM) and arrive at Buffalo (BUF).
Which airports do connecting flights from Des Moines to Buffalo pass through?
One-stop flights from Des Moines to Buffalo most commonly connect through:

• Chicago O'Hare Intl (ORD) - 62% of one-stop connections
• Detroit Metropolitan Wayne County (DTW) - 19% of one-stop connections
• Philadelphia (PHL) - 10% of one-stop connections
• Charlotte Douglas (CLT) - 5% of one-stop connections
Can I save money by using flexible dates for flights from Des Moines to Buffalo?
Yes. Flexible dates can save you up to 51% on flights from Des Moines to Buffalo. Saturday is the cheapest departure day at $313 round-trip on average, while Sunday is the most expensive at $636, a difference of $323.

Cheaper weekend fares like these are typical of routes dominated by weekday business travel.
How much time can I save by choosing a different layover airport from Des Moines to Buffalo?
Flying via Chicago Midway (MDW) gives the shortest average 1-stop total travel time at 4h 14m, compared with 4h 36m via Detroit Metropolitan Wayne County (DTW) and 4h 55m via Chicago O'Hare Intl (ORD).
What is the time difference between Des Moines and Buffalo?
Buffalo is 1 hour ahead of Des Moines (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

If your dates are flexible, aim for a Saturday departure and avoid flying on Sunday. On this route, Saturday flights average $313, about $323 less than Sunday fares (51% savings) based on the last 12 months.
If you can choose when to travel, plan your Des Moines to Buffalo trip for August. Fares historically average $324 round-trip in that month - typically $412 less than the most expensive month, which is March (based on the last 12 months).
If you're arriving late at night and need somewhere to stay, check out these hotels close to Buffalo Airport.

• Aloft Buffalo Airport
• Comfort Inn and Suites Buffalo Airport
• TownePlace Suites by Marriott Buffalo Airport

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DSM - BUF

$163 Find Cheap Flights from Des Moines to Buffalo - Compare and Save

Everything you should know

Cheap Flights from Des Moines to Buffalo (DSM-BUF)

Recent round-trip flight deals from Des Moines to Buffalo

Recent one-way flight deals from Des Moines to Buffalo

Recent last minute flight deals from Des Moines to Buffalo

Price, demand and travel trends for Des Moines to Buffalo flights

How much is a round-trip flight from Des Moines to Buffalo?

What's the cheapest day of the week to fly from Des Moines to Buffalo?

Which airline is the cheapest to fly from Des Moines to Buffalo?

What’s the most popular layover airport when flying from Des Moines to Buffalo?

What is the cheapest layover airport when flying from Des Moines to Buffalo?

When flying from Des Moines to Buffalo which airport offers the shortest layover?

Key details for Des Moines to Buffalo flights

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Cheapest flight

When to book flights from Des Moines to Buffalo

Your Des Moines to Buffalo flight questions, answered

Your guide to booking Des Moines to Buffalo flights

More options for your flight from Des Moines to Buffalo

Complete your trip to Buffalo with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Des Moines to Buffalo

Find direct flights to and from Des Moines and Buffalo

Flights from domestic origins to Buffalo

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