DSM - BUF

$194 Find Cheap Flights from Des Moines to Buffalo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Buffalo departing on 3/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Buffalo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Buffalo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Buffalo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$352
Delta
Fri 3/27Wed 4/1
DSM - BUF • 1 stop
Cheapest one-way
$194
Typical prices: $112-$308
American Airlines
Fri 3/27
DSM - BUF • 1 stop
Top airlines
Delta
Cheapest • from $352 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Buffalo (DSM-BUF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Buffalo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Buffalo

Fri, Mar 27 - Wed, Apr 1
Delta Logo
6:15 am - 11:44 am
DSM
-
BUF
4h 29m
1 stop
Delta Logo
6:15 am - 9:46 am
BUF
-
DSM
4h 31m
1 stop
$352Delta
Fri, Mar 27 - Wed, Apr 1
American Airlines Logo
7:45 am - 3:25 pm
DSM
-
BUF
6h 40m
1 stop
American Airlines Logo
5:00 pm - 11:48 pm
BUF
-
DSM
7h 48m
2 stops
$357American Airlines
Fri, Mar 27 - Wed, Apr 1
American Airlines Logo
5:00 am - 1:42 pm
DSM
-
BUF
7h 42m
2 stops
American Airlines Logo
5:00 pm - 11:48 pm
BUF
-
DSM
7h 48m
2 stops
$362American Airlines
Fri, May 15 - Mon, May 18
American Airlines Logo
8:56 am - 2:21 pm
DSM
-
BUF
4h 25m
1 stop
American Airlines Logo
6:00 am - 10:26 am
BUF
-
DSM
5h 26m
1 stop
$364American Airlines
Fri, Mar 27 - Wed, Apr 1
American Airlines Logo
5:00 am - 11:49 am
DSM
-
BUF
5h 49m
1 stop
American Airlines Logo
5:29 pm - 10:10 pm
BUF
-
DSM
5h 41m
1 stop
$383American Airlines
Tue, Jun 9 - Thu, Jun 11
United Airlines Logo
1:05 pm - 9:02 pm
DSM
-
BUF
6h 57m
1 stop
United Airlines Logo
5:47 pm - 10:51 pm
BUF
-
DSM
6h 04m
1 stop
$387United Airlines
Tue, Jun 9 - Thu, Jun 11
United Airlines Logo
6:00 am - 2:13 pm
DSM
-
BUF
7h 13m
2 stops
United Airlines Logo
7:00 am - 10:21 am
BUF
-
DSM
4h 21m
1 stop
$392United Airlines
Fri, Mar 27 - Wed, Apr 1
American Airlines Logo
5:00 am - 1:42 pm
DSM
-
BUF
7h 42m
2 stops
American Airlines Logo
5:00 pm - 11:48 pm
BUF
-
DSM
7h 48m
2 stops
$393American Airlines
Sat, Feb 28 - Tue, Mar 3
Southwest Logo
6:10 am - 4:15 pm
DSM
-
BUF
9h 05m
1 stop
Southwest Logo
1:20 pm - 9:10 pm
BUF
-
DSM
8h 50m
2 stops
$397Southwest
Sat, Feb 28 - Tue, Mar 3
Southwest Logo
6:10 am - 8:30 pm
DSM
-
BUF
13h 20m
2 stops
Southwest Logo
1:20 pm - 9:10 pm
BUF
-
DSM
8h 50m
2 stops
$402Southwest
Booking Insights

KAYAK's insights & trends for Des Moines to Buffalo flights

Get data-powered insights and trends into flights from Des Moines to Buffalo to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to Buffalo?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to Buffalo were found on Delta ($352) and American Airlines ($357).

Good to know

Low seasonOctober
Cheapest flight$194
Best time to beat the crowds with an average 41% drop in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Des Moines to Buffalo

When to book flights from Des Moines to Buffalo

Are your dates flexible? Find out the best times to travel from Des Moines to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Buffalo

  • What is the cheapest flight from Des Moines to Buffalo?

    In the last 3 days, the lowest price for a flight from Des Moines to Buffalo was $194 for a one-way ticket and $352 for a round-trip.

  • Do I need a passport to fly between Des Moines and Buffalo?

    No, a passport isn't needed to fly from Des Moines to Buffalo. However, local authorities might ask for an official ID.

  • Which aircraft models fly most regularly from Des Moines to Buffalo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Buffalo?

    Star Alliance, oneworld, and SkyTeam are the airline alliances operating flights between Des Moines and Buffalo, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Buffalo, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Buffalo are Delta and United Airlines. With an average price for the route of $332 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $463 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Des Moines to Buffalo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Buffalo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Buffalo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Buffalo from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Buffalo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Buffalo with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and BUF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Buffalo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Buffalo from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Des Moines to Buffalo

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Buffalo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Buffalo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8178 reviews
7.8Entertainment
8.1Boarding
7.2Food
7.9Comfort
8.5Crew
Airline reviews

This was one of the worst flights I’ve been on in years. I upgraded to comfort and had such an uncomfortable experience. The person next to me was oversized - which I understand - however, they took up their space and mine. I could only use about 50% of my seat space to not be physically touching this person the entire flight and there was no spatial awareness. I also could not use the seat outlet because their body was obstructing it. It was very inconvenient. Their body kept touching me repeatedly during the flight and I felt very uncomfortable. To pay more for an upgraded space and then not even being able to use it was highly disappointing.

2.0 MediocreMichael, Feb 2026
ORD - LGA
Read more Delta reviews

This was one of the worst flights I’ve been on in years. I upgraded to comfort and had such an uncomfortable experience. The person next to me was oversized - which I understand - however, they took up their space and mine. I could only use about 50% of my seat space to not be physically touching this person the entire flight and there was no spatial awareness. I also could not use the seat outlet because their body was obstructing it. It was very inconvenient. Their body kept touching me repeatedly during the flight and I felt very uncomfortable. To pay more for an upgraded space and then not even being able to use it was highly disappointing.

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

Air travel sucks. It continues to be awful for all airlines. No shame on delta alone.

Delta canceled our flight and we had to scramble to find another airline to get home. Phoenix is not a delta hub so they didn’t have another plane. It would have been a red eye though Salt Lake City. Getting in at 5am. No bueno.

Flight delays both to Detroits and return flight . The flight to Detroit was associated with mechanical difficulty

The food is terrible. The staff is wonderful. Comfort is good.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Staff was exceptional! Everyone was kind, professional and friendly making the trip very pleasant. Thank you!

The flight used a B767 with a very old interior from before 2014. The entertainment system did not work at all during the flight despite attempts to reset the system. It was like they flew this route just to be competitive.

Delta made it easy, comfortable and timely. The crew was fantastic.

Short flight, but no drink/snack service. The flights both going and coming were delayed.

Much better than Spirit. I was please by the easy fast check in and boarding

Everything was on time Will use united again for sure

Plane outlets in my row not working to charge phone. Staff response was, well it should be. Plug into seed for volume not working well. Had to find the sweet spot for plug in or it would shut off and on.

Fine not above and beyond as I had a connection that was delayed due to maintenance

The power at the seat didn't work and the seat itself was difficult to adjust - this was a business class seat. Flight attendant gave me miles to compensate. The attendant was very professional and on top of his game the entire flight.

I upgraded my seat and was promised it would be next to the emergency door for extra leg room and they said it was premium plus but it was at the back of the plane...same thing happened from Newark to Dubai

Everything except the food and entertainment. It was a great experience though

Bad food, bad service, cold cabin with no additional blankets when asked for (they told me they don’t provide additional blankets). I’m a frequent traveler and this is one of the worst companies I traveled with (by the way I thought that I booked my ticket with Lufthansa but I didn’t see that the flights were handled by United).

United Airlines is my preferred airlines and I am thankful for Gary who also help support me on the phone to switch my flight literally last min.

Delayed an hour due to operational issues. Minimal apologies or care for the significant inconvenience caused. Landed at nearly 1am and they still couldn’t find ground staff to get us off the plane promptly.

Long delays, lack of information about the status of the flight. The flight was delayed 4 times.

It was good. But the gate team made me check my carry on when there was plenty of space for my luggage on the plane. Otherwise our trip was fine.

Bags took over and hour to come out. Delays due to wind caused rebooking.

Gate was overcrowded. Gate agents performed very well. Flight crew was top notch! Efficient & professional & courteous. Both meals not thermalized well. Dinner main dish was actually cold in the center. Almost inedible. Breakfast sandwich was lukewarm.

RIC Staff was not enough. Elderly passengers had to wait 30 minutes to deplane, so we could board and still had to walk as no chairs were provided. And, passenger in front of my seat assignment rammed seat against my legs entire flight time. Was mildly bruised and left thigh still sore.

Flight was cancelled 3 hrs AFTER etd. Thetefore Missed connection from JFK to New Zealand . No accommodation provided… This cost ne aporox 1000 USD in extra expenses and turned whst should have been a 24 hr trip ftom Boston - New Zealand into a VERY expensive , late 70+ hr nightmare … Complete nonsense!!!

Overall fine, but the delay was annoying and the reasons for the delay were not communicated. The crew on board were phenomenal!

Whenever a passenger purchase a ticket his advantage number should automatically to his information. It's not everyone remember the number. You request for your number and American airline agent say they will email it....and they never email anything and you loose your mileage just because you don't remember your number. It should automatically go your information and associate with your email account at all times

In flight connectivity (via T-Mobile) was often not working.

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