DSM - BUF

$188 Find Cheap Flights from Des Moines to Buffalo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Buffalo departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Buffalo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Buffalo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Buffalo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$335
Typical prices: $441-$112
Southwest
Wed 6/17Wed 6/24
DSM - BUF • 1 stop
Cheapest one-way
$188
United Airlines
Mon 5/25
DSM - BUF • 1 stop
Top airlines
Cheapest • from $335 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Buffalo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $312 (round-trip)
Shortest trip • 4h 26m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 61% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Buffalo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Buffalo (DSM-BUF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Buffalo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Buffalo

Wed, Jun 17 - Wed, Jun 24
Southwest Logo
3:45 pm - 9:25 pm
DSM
-
BUF
4h 40m
1 stop
Southwest Logo
7:10 pm - 10:45 pm
BUF
-
DSM
4h 35m
1 stop
$335Southwest
Wed, May 27 - Mon, Jun 1
Delta Logo
11:57 am - 6:44 pm
DSM
-
BUF
5h 47m
1 stop
Delta Logo
6:15 am - 1:37 pm
BUF
-
DSM
8h 22m
1 stop
$355Delta
Wed, May 27 - Mon, Jun 1
United Airlines Logo
5:00 am - 2:25 pm
DSM
-
BUF
8h 25m
2 stops
United Airlines Logo
7:00 am - 10:27 am
BUF
-
DSM
4h 27m
1 stop
$360United Airlines
Wed, Aug 12 - Sat, Aug 15
American Airlines Logo
6:00 am - 11:58 am
DSM
-
BUF
4h 58m
1 stop
American Airlines Logo
5:50 pm - 11:57 pm
BUF
-
DSM
7h 07m
1 stop
$371American Airlines
Wed, Jun 17 - Wed, Jun 24
Southwest Logo
3:45 pm - 9:25 pm
DSM
-
BUF
4h 40m
1 stop
Southwest Logo
12:50 pm - 10:45 pm
BUF
-
DSM
10h 55m
2 stops
$376Southwest
Wed, May 27 - Mon, Jun 1
Southwest Logo
5:30 am - 4:20 pm
DSM
-
BUF
9h 50m
2 stops
Southwest Logo
4:00 pm - 11:05 pm
BUF
-
DSM
8h 05m
2 stops
$385Southwest
Wed, Sep 30 - Mon, Oct 5
Delta Logo
10:55 am - 6:33 pm
DSM
-
BUF
6h 38m
1 stop
Delta Logo
3:50 pm - 8:45 pm
BUF
-
DSM
5h 55m
1 stop
$391Delta
Wed, Jun 17 - Wed, Jun 24
American Airlines Logo
6:30 am - 12:19 pm
DSM
-
BUF
4h 49m
1 stop
American Airlines Logo
6:02 am - 12:52 pm
BUF
-
DSM
7h 50m
2 stops
$400American Airlines
Wed, Sep 30 - Mon, Oct 5
Southwest Logo
7:15 am - 5:45 pm
DSM
-
BUF
9h 30m
2 stops
Southwest Logo
8:05 am - 11:20 am
BUF
-
DSM
4h 15m
1 stop
$406Southwest
Fri, May 8 - Sun, May 10
Southwest Logo
5:25 am - 10:15 am
DSM
-
BUF
3h 50m
1 stop
Southwest Logo
7:50 pm - 11:20 pm
BUF
-
DSM
4h 30m
1 stop
$407Southwest
Booking Insights

KAYAK's insights & trends for Des Moines to Buffalo flights

Get data-powered insights and trends into flights from Des Moines to Buffalo to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Des Moines to Buffalo?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Buffalo, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Buffalo is June, where tickets cost $148 (return) on average. On the other hand, the most expensive months are March and May, where the average cost of round-trip tickets is $736 and $538 respectively.

Good to know

Low seasonJanuary
Cheapest flight$188
Best time to beat the crowds but there is an average 9% increase in price.
Most popular time to fly and prices are also 22% lower on average.
Flight from Des Moines to Buffalo

When to book flights from Des Moines to Buffalo

Are your dates flexible? Find out the best times to travel from Des Moines to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Buffalo

  • What is the cheapest flight from Des Moines to Buffalo?

    In the last 3 days, the lowest price for a flight from Des Moines to Buffalo was $188 for a one-way ticket and $335 for a round-trip.

  • Do I need a passport to fly between Des Moines and Buffalo?

    No, a passport isn't needed to fly from Des Moines to Buffalo. However, local authorities might ask for an official ID.

  • Which aircraft models fly most regularly from Des Moines to Buffalo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Buffalo?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between Des Moines and Buffalo, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Buffalo, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Buffalo are Delta and United Airlines. With an average price for the route of $332 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $441 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Des Moines to Buffalo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Buffalo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Buffalo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Buffalo from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Buffalo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Buffalo with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and BUF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Buffalo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Buffalo from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Des Moines to Buffalo

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Buffalo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Buffalo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8388 reviews
7.2Food
8.1Boarding
8.5Crew
7.9Comfort
7.8Entertainment
Airline reviews

The flight was delayed 90 minutes The Gate was wrong The Restroom on Aircraft was not clean There was a half used water bottle in my seat

2.0 MediocreJames, Mar 2026
BOS - LGA
Read more Delta reviews

The flight was delayed 90 minutes The Gate was wrong The Restroom on Aircraft was not clean There was a half used water bottle in my seat

Too many people are taking up space in the overhead bins with their extra piece of luggage. Since they cannot fit their backpacks or extra luggage piece under the seat in front of them, they store it in the overheads and thus taking up room for other passengers. It wasn’t only one or two persons; more like 12 or 13 passengers.

Got to fly my favorite plane, the Boeing 767-400ER, to Milan. The soft blush pink mood lighting during meal service was very beautiful and gorgeous. The service was top-notch, and our flights were on time. I highly recommend Delta.

Cabin was not pressurized properly. Several passengers had respiratory difficulties.

The staff was fine. The plane was extremely tight, and I paid for the wifi and it did not work at all. I was actually going to ask for a refund.

Terrible. Four hour delay because Delta could not find crew to man the aircraft. Terrible communication. Terrible insight into the delays. One of the worst flight experiences I’ve had.

The crew, and fellow passengers, were super gracious and kind. There seemed to be plenty of bin space even though the plane was full. It’s nice to get a glass of wine with dinner in Premiere seating, and there was a lot of food.

Good experience and the flight landed early. There was no food I had or entertainment.

bulkhead seat had very little legroom - even in bsiness class.

This was one of the worst flights I’ve been on in years. I upgraded to comfort and had such an uncomfortable experience. The person next to me was oversized - which I understand - however, they took up their space and mine. I could only use about 50% of my seat space to not be physically touching this person the entire flight and there was no spatial awareness. I also could not use the seat outlet because their body was obstructing it. It was very inconvenient. Their body kept touching me repeatedly during the flight and I felt very uncomfortable. To pay more for an upgraded space and then not even being able to use it was highly disappointing.

Flights were on time actually early service was good and crew cheerful

Every staff member was professional, friendly and courteous. The pizza twist was ok. It was warm but too much dough.

I had a terrible experience. My flight got delayed from Atlanta to Chicago on Monday April 6, 2026, and that led to me missing my next flight to Brussels. United Airlines didn’t provide me with any accommodation for shelter. I had to sleep at the airport in Chicago. The next flight I was put on didn’t leave until the evening hours of Tuesday 4/7/2026.

Boarding was again a "free for all". We were boarding group 4, and almost the entire plane was able to board before us. It's a shame that someone who follows the rules, gets the short end of the stick. Not fair.

Flight left on time, arrived early, pleasant staff provided water, coffee, etc. access to bathrooms was reasonable and were well maintained. blankets were available, lots of entertainment options. LUGGAGE SERVICE WAS GREAT. I got my one checked bag quickly and was able to make a bus connection for a 2 hour bus ride saving me from waiting another 1.5 hours.

The boarding process was straightforward. One pertinent observation regarding all boarding procedures is that if an individual requires assistance or possesses a special status and is part of preboarding, it is advisable to limit the number of passengers who can preboard with them, rather than the entire, sometimes large, companion groups. The seats are uncomfortable, and the entertainment options are significantly inferior compared to other airlines. During the snack service, I requested an additional bag of snacks, but my request was denied. Initially, the flight attendant agreed to my request.becoming a strange accurate moment. The flight duration was four hours.

The flight was officially delayed 3 times, and was actually later than that. Combined, it was a 3 hour delay, but there was no recognition (miles, voucher, etc). The crew seemed stressed. The captain sounded nervous in his announcements. The flight itself was smooth and uneventful.

United didn’t even try to hold the flight for me. They knew I had a tight connection and when I arrived at the gate less than 10 mins after final boarding the flight had already gone. The gate agent wasn’t even notified that I was on my way. She was told I wasn’t at the airport

It was perfect! I've never flown with United before, but I definitely will in the future

I had a cancelled flight because of technical issues going to my destination, and a delayed flight coming home. All told it wasn’t a total bust.

We left at 1030 am pacific from LA and supposed to land at 7 pm Eastern in NY. They made a detour, stopped in Philadelphia and didn’t land till 1130 PM Eastern!!! Worst flight experience with no pilot communication with no explanation as to what was going on. Everyone was very frustrated to say the least.

Found that the plane used for this short flight is smaller and therefore the seats are really squeezed tight.

The flight itself was excellent but the gate attendant made me check my carryon since she said it was an inch too big. I’ve had no problems with this carryon on recent flights on Qantas, Delta, Austrian, Southwest Airlines even though the overhead bins are the same size. there were other carryons in the bins that also looked larger than mine and there was room left in the bins for more. When I picked up my carryon from baggage claim one of the wheels had broken off.

Ceiling fell down and had to have maintenance come and duct tape it up. No WiFi on the flight.

Flight was scheduled at 11:26am but they keep Delaying until midnight. They waited at airport restless.

Really good. I accidentally left my duffel on the plane and the reps were so friendly in retrieving it.

Our flight was delayed 3 times and this is why I am giving such low reviews. Everything else was okay but being in the airport at 4:30pm for my initial flight at 7pm to not leave until after 9:30pm is insane,

The crew was excellent and overall the flight was good. No complaints.

Good crew and flight was on time. It’s a small plane with limited overhead luggage space. They said the overhead space was full and I had to check my bag. There was still space when I got on. Waiting for my checked luggage added 30 minutes to my trip. Not the end of the world but also not great.

My seat was assigned last row behind restrooms No legroom’s I’m very Pettit Still was not comfortable Food choice was excellent

Everything you need to know for your flight from Des Moines to Buffalo

Information on your arrival and departure airports