DSM - BUF

$384 Find Cheap Flights from Des Moines to Buffalo

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Buffalo departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Buffalo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Buffalo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Buffalo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$317
Delta
Tue 2/24Tue 3/3
DSM - BUF • 1 stop
Cheapest one-way
Multiple Airlines
Tue 1/13
DSM - BUF • multi-stop
Top airlines
Delta
Cheapest • from $317 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Buffalo (DSM-BUF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Buffalo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Buffalo

Tue, Feb 24 - Tue, Mar 3
Delta Logo
6:19 am - 11:43 am
DSM
-
BUF
4h 24m
1 stop
Delta Logo
12:05 pm - 4:27 pm
BUF
-
DSM
5h 22m
1 stop
$317Delta
Thu, Apr 9 - Sun, Apr 12
Southwest Logo
5:25 am - 10:15 am
DSM
-
BUF
3h 50m
1 stop
Southwest Logo
7:50 pm - 11:20 pm
BUF
-
DSM
4h 30m
1 stop
$384Southwest
Thu, Apr 9 - Sun, Apr 12
Southwest Logo
5:25 am - 10:15 am
DSM
-
BUF
3h 50m
1 stop
Southwest Logo
5:50 am - 11:30 am
BUF
-
DSM
6h 40m
2 stops
$389Southwest
Tue, Feb 24 - Tue, Mar 3
United Airlines Logo
3:24 pm - 8:51 pm
DSM
-
BUF
4h 27m
1 stop
United Airlines Logo
2:54 pm - 9:41 pm
BUF
-
DSM
7h 47m
2 stops
$392United Airlines
Tue, Feb 24 - Tue, Mar 3
United Airlines Logo
3:24 pm - 11:44 pm
DSM
-
BUF
7h 20m
2 stops
United Airlines Logo
1:52 pm - 11:43 pm
BUF
-
DSM
10h 51m
2 stops
$398United Airlines
Fri, Jan 30 - Mon, Feb 2
Delta Logo
7:34 am - 2:10 pm
DSM
-
BUF
5h 36m
1 stop
Delta Logo
5:44 pm - 8:54 pm
BUF
-
DSM
4h 10m
1 stop
$404Delta
Fri, Jan 30 - Mon, Feb 2
American Airlines Logo
1:16 pm - 10:43 pm
DSM
-
BUF
8h 27m
2 stops
American Airlines Logo
5:12 am - 12:46 pm
BUF
-
DSM
8h 34m
1 stop
$409American Airlines
Fri, Jun 5 - Fri, Jun 12
American Airlines Logo
6:00 am - 2:21 pm
DSM
-
BUF
7h 21m
1 stop
American Airlines Logo
10:07 am - 1:15 pm
BUF
-
DSM
4h 08m
1 stop
$427American Airlines
Fri, Jun 5 - Fri, Jun 12
American Airlines Logo
7:58 pm - 12:52 am
DSM
-
BUF
3h 54m
1 stop
American Airlines Logo
10:07 am - 1:15 pm
BUF
-
DSM
4h 08m
1 stop
$447American Airlines
Fri, Jan 30 - Mon, Feb 2
Southwest Logo
6:10 am - 3:10 pm
DSM
-
BUF
8h 00m
2 stops
Southwest Logo
1:20 pm - 9:10 pm
BUF
-
DSM
8h 50m
2 stops
$448Southwest
Booking Insights

KAYAK's insights & trends for Des Moines to Buffalo flights

Get data-powered insights and trends into flights from Des Moines to Buffalo to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to Buffalo?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to Buffalo were found on Delta ($317) and Southwest ($384).

Which airlines fly non-stop between Des Moines and Buffalo?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Des Moines to Buffalo.

There are 3 airlines that fly nonstop from Des Moines to Buffalo. They are: American Airlines, Delta and United Airlines. The cheapest price of all airlines flying this route was found with Delta at $148 for a round-trip flight. On average, the best prices for this route can be found at American Airlines.

Good to know

Low seasonOctober
Cheapest flight$317
Best time to beat the crowds with an average 39% drop in price.
Most popular time to fly and prices are also 23% lower on average.
Flight from Des Moines to Buffalo

When to book flights from Des Moines to Buffalo

Are your dates flexible? Find out the best times to travel from Des Moines to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Buffalo

  • What is the cheapest flight from Des Moines to Buffalo?

    In the last 3 days, the lowest price for a flight from Des Moines to Buffalo was $384 for a round-trip ticket.

  • Do I need a passport to fly between Des Moines and Buffalo?

    No, a passport isn't needed to fly from Des Moines to Buffalo. However, local authorities might ask for an official ID.

  • Which aircraft models fly most regularly from Des Moines to Buffalo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Buffalo?

    Star Alliance, oneworld, and SkyTeam are the airline alliances operating flights between Des Moines and Buffalo, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Buffalo, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Buffalo are Delta and United Airlines. With an average price for the route of $332 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $463 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Des Moines to Buffalo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Buffalo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Buffalo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Buffalo from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Buffalo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Buffalo with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and BUF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Buffalo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Buffalo from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Des Moines to Buffalo

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Buffalo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Buffalo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8039 reviews
8.1Boarding
8.5Crew
7.8Entertainment
7.9Comfort
7.2Food
Airline reviews

Air travel sucks. It continues to be awful for all airlines. No shame on delta alone.

4.0 OkayStephen, Jan 2026
LAS - JFK
Read more Delta reviews

Air travel sucks. It continues to be awful for all airlines. No shame on delta alone.

Delta canceled our flight and we had to scramble to find another airline to get home. Phoenix is not a delta hub so they didn’t have another plane. It would have been a red eye though Salt Lake City. Getting in at 5am. No bueno.

Flight delays both to Detroits and return flight . The flight to Detroit was associated with mechanical difficulty

The food is terrible. The staff is wonderful. Comfort is good.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Staff was exceptional! Everyone was kind, professional and friendly making the trip very pleasant. Thank you!

The flight used a B767 with a very old interior from before 2014. The entertainment system did not work at all during the flight despite attempts to reset the system. It was like they flew this route just to be competitive.

Delta made it easy, comfortable and timely. The crew was fantastic.

On this flight I felt the food offering was not as complete as on previous flights. The tomato salad was a bit off and there was nothing additional such a bread or butter. The breakfast was only one option, so you either ate what they had or ate nothing. The crew was efficient, but most seemed frustrated throughout the flight. The flight arrived early and was obstacle-free, so I’m overall quite happy, but the shine in the rest of the experience just wasn’t there.

Great flight with Delta! Boarding was quick and easy, the amenities were solid, and the plane was in great shape. The flight attendants had a fun, lively energy while staying professional. All in all, a smooth trip — even managed to catch up on some rest. Thanks, Delta!

Miserable. They moved my seat, but canceled the next leg of my flight. I resolved the issue at my transfer, but that resulted in lost luggage that has taken days off my schedule with no resolution. Worse, they fail to interface effectively with Lufthansa, forcing me to bounce between two equally useless help desks. The apps are unable to handle the situation, the bag dropped off the tracker, and while the call centers are polite, they do not provide written information to assist with cross-airline communication.

left on time, reasonable boarding process arrived early luggage came out quickly

I like flying first class, and United has a nice one

Teeny tiny bathrooms, crew was not realistic about when we'd arrive.

Check-in, boarding and the flight from Phoenix to Houston was quick and easy. The flight from Houston to Shreveport was delayed 5 hours. It was frustrating but I think United handled it the best they could.

They lost my luggage, so, not happy. The crew was nice but my suitcases never made it, still trying to find out what happened!

The staff was hospitable and professional. The seat had a bit of wear. The winner shade was stuck 1/4 open. I received the best of both worlds. The morning sun was able to come in and blind the screen i was trying to use while at the same time it was too low to look out and enjoy the view. Rather embarrassing for a 1st class ticket.

Perfect flight. Smooth flight. Arrived 20 minutes early at destination. Excellent service.

The flights were on time which was great give. It was holiday travel season and there’d been some weather issues. The only complaint and this is every time with United is the terrible seat design. The head rest is not built for comfort and having my neck bent forward for a cross country trip reminded me while I try not to take United flights as a rule.

I’m so sorry, I can’t remember her name, I believe it was Dimpti. She was stellar, also a mature Asian flight attendant, lots of flowers in her hair, just as amazing! But literally the crew was AWESOME . Only downside is there weren’t any charging outlets. Maybe I needed to ask a flight attendant , but it would’ve been nice to have one easily accessible.

Bags took over and hour to come out. Delays due to wind caused rebooking.

Gate was overcrowded. Gate agents performed very well. Flight crew was top notch! Efficient & professional & courteous. Both meals not thermalized well. Dinner main dish was actually cold in the center. Almost inedible. Breakfast sandwich was lukewarm.

RIC Staff was not enough. Elderly passengers had to wait 30 minutes to deplane, so we could board and still had to walk as no chairs were provided. And, passenger in front of my seat assignment rammed seat against my legs entire flight time. Was mildly bruised and left thigh still sore.

Flight was cancelled 3 hrs AFTER etd. Thetefore Missed connection from JFK to New Zealand . No accommodation provided… This cost ne aporox 1000 USD in extra expenses and turned whst should have been a 24 hr trip ftom Boston - New Zealand into a VERY expensive , late 70+ hr nightmare … Complete nonsense!!!

Overall fine, but the delay was annoying and the reasons for the delay were not communicated. The crew on board were phenomenal!

Whenever a passenger purchase a ticket his advantage number should automatically to his information. It's not everyone remember the number. You request for your number and American airline agent say they will email it....and they never email anything and you loose your mileage just because you don't remember your number. It should automatically go your information and associate with your email account at all times

In flight connectivity (via T-Mobile) was often not working.

Boarding took forever, the plane was cramped and cold, and the seatbelt song came on constantly throughout the red eye flight with a loud pre-recorded message playing each time

Cabin felt crammed Snacks are lame But crew was super efficient getting us out on time despite delay

Flight was empty so had a whole row to myself. Still had to wait to get the bag due to the negligence at Palm Springs departure.

Everything you need to know for your flight from Des Moines to Buffalo

Information on your arrival and departure airports