Which airports can I use when flying from Des Moines to Buffalo?

Flights from Des Moines to Buffalo usually depart from Des Moines (DSM) and arrive at Buffalo (BUF).

What cabin classes can I book on flights from Des Moines to Buffalo?

Only Economy Class is available on flights from Des Moines to Buffalo.

Which airports do connecting flights from Des Moines to Buffalo pass through?

One-stop flights from Des Moines to Buffalo most commonly connect through: • Chicago O'Hare Intl (ORD) - 53% of one-stop connections • Detroit Metropolitan Wayne County (DTW) - 37% of one-stop connections • Charlotte Douglas (CLT) - 3% of one-stop connections • Chicago Midway (MDW) - 3% of one-stop connections Chicago O'Hare Intl (ORD) handles the largest share of one-stop connections on this route.

Can I save money by using flexible dates for flights from Des Moines to Buffalo?

On the Des Moines to Buffalo route, being flexible with your departure day can save you up to 51%. Saturday is the cheapest day at $317 round-trip on average, while Sunday is the most expensive at $636: a $319 difference. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

How long is a flight from Des Moines to Buffalo?

A nonstop flight from Des Moines to Buffalo takes 0h 00m, covering 768 miles.

Do I need a passport to fly from Des Moines to Buffalo?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

Have flight prices from Des Moines to Buffalo changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $364 to $960. That means the highest observed fare was about 3x higher than the lowest one.

How much time can I save by choosing a different layover airport from Des Moines to Buffalo?

Flying via Chicago Midway (MDW) gives the shortest average 1-stop total travel time at 4h 14m, compared with 4h 25m via Detroit Metropolitan Wayne County (DTW) and 4h 54m via Chicago O'Hare Intl (ORD).

What is the time difference between Des Moines and Buffalo?

Buffalo is 1 hour ahead of Des Moines (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Buffalo Airport (BUF)?

Buffalo Airport (BUF) hosts 5 major car rental companies, with daily rates starting from around $19 for economy cars. Top options include: • Dollar • Budget • Hertz • Alamo • Thrifty

How much should I expect to pay for a Des Moines to Buffalo flight?

Round-trip flights from Des Moines to Buffalo range from $317 to $463, with an average of $382 over the past 12 months. Anything below $317 counts as a good deal.

What is the cheapest airline to fly from Des Moines to Buffalo?

United Airlines ($364) and American Airlines ($371) are the cheapest airlines to fly round-trip from Des Moines to Buffalo according to KAYAK data over the last 5 days.

What is the most popular layover airport when flying from Des Moines to Buffalo?

Chicago O'Hare Intl (ORD) is the most popular layover for the Des Moines to Buffalo route. 53% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via ORD.

What is the cheapest layover airport when flying from Des Moines to Buffalo?

Flights via Detroit Metropolitan Wayne County (DTW) offer the most affordable fares, with an average round-trip price of $343. Based on KAYAK data over the past 3 months.

When flying from Des Moines to Buffalo which airport offers the shortest layover?

Chicago Midway (MDW) had the shortest average connection time for Des Moines to Buffalo layovers at 164 minutes over the past 3 months.

$364 CHEAP FLIGHTS from Des Moines to Buffalo (DSM - BUF)

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Cheapest round-trip

$364

Typical prices: $317-$463

United Airlines

Tue 10/2Sat 10/6

DSM - BUF • 1 stop

Nonstop flights

Not available

There are currently no direct flights between Des Moines and Buffalo. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

September

Cheapest • 17% price drop

August

Most popular

Good to know

Top layover airports

Detroit Metropolitan Wayne County (DTW)

Cheapest • Avg $343 (round-trip)

Chicago Midway (MDW)

Shortest trip • 4h 14m (one-way)

Insights

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Flight Deals

Cheap Flights from Des Moines to Buffalo (DSM-BUF)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Des Moines to Buffalo

Fri, Oct 2 - Tue, Oct 6

3:11 pm - 8:47 pmDSM Des Moines-BUF Buffalo

4h 36m1 stop Chicago O'Hare Intl

5:45 pm - 11:35 pmBUF Buffalo-DSM Des Moines

6h 50m1 stop Chicago O'Hare Intl

$364United Airlines

Fri, Oct 2 - Tue, Oct 6

6:00 am - 1:53 pmDSM Des Moines-BUF Buffalo

6h 53m1 stop Washington, D.C. Reagan-National

6:08 am - 1:30 pmBUF Buffalo-DSM Des Moines

8h 22m2 stops New York LaGuardia Chicago O'Hare Intl

$371American Airlines

Wed, Oct 21 - Sun, Oct 25

5:50 pm - 11:59 pmDSM Des Moines-BUF Buffalo

5h 09m1 stop Detroit Metropolitan Wayne County

6:15 am - 9:42 amBUF Buffalo-DSM Des Moines

4h 27m1 stop Detroit Metropolitan Wayne County

$371Delta

Thu, Oct 22 - Sun, Oct 25

10:22 am - 3:13 pmDSM Des Moines-BUF Buffalo

3h 51m1 stop Detroit Metropolitan Wayne County

6:15 am - 9:42 amBUF Buffalo-DSM Des Moines

4h 27m1 stop Detroit Metropolitan Wayne County

$371Delta

Wed, Oct 21 - Sun, Oct 25

5:35 am - 2:35 pmDSM Des Moines-BUF Buffalo

8h 00m2 stops Chicago Midway Nashville Intl

8:00 am - 11:20 amBUF Buffalo-DSM Des Moines

4h 20m1 stop Chicago Midway

$376Southwest

Sat, Oct 3 - Mon, Oct 5

2:44 pm - 10:10 pmDSM Des Moines-BUF Buffalo

6h 26m1 stop Chicago O'Hare Intl

7:53 pm - 11:58 pmBUF Buffalo-DSM Des Moines

5h 05m1 stop Charlotte Douglas

$391American Airlines

Fri, Oct 16 - Sun, Oct 18

5:50 pm - 11:59 pmDSM Des Moines-BUF Buffalo

5h 09m1 stop Detroit Metropolitan Wayne County

12:15 pm - 4:55 pmBUF Buffalo-DSM Des Moines

5h 40m1 stop Detroit Metropolitan Wayne County

$396Delta

Sat, Jan 30 - Wed, Feb 3

3:25 pm - 8:52 pmDSM Des Moines-BUF Buffalo

4h 27m1 stop Chicago O'Hare Intl

6:30 am - 12:27 pmBUF Buffalo-DSM Des Moines

6h 57m1 stop Chicago O'Hare Intl

$405United Airlines

Sat, Jan 30 - Wed, Feb 3

8:00 am - 1:15 pmDSM Des Moines-BUF Buffalo

4h 15m1 stop Chicago O'Hare Intl

1:50 pm - 5:41 pmBUF Buffalo-DSM Des Moines

4h 51m1 stop Chicago O'Hare Intl

$405United Airlines

Sat, Jan 30 - Wed, Feb 3

1:45 pm - 10:54 pmDSM Des Moines-BUF Buffalo

8h 09m1 stop Denver Intl

10:20 am - 8:32 pmBUF Buffalo-DSM Des Moines

11h 12m2 stops Chicago O'Hare Intl Denver Intl

$410United Airlines

Recent last minute flight deals from Des Moines to Buffalo

Mon, Sep 14 - Wed, Sep 16

6:00 am - 2:26 pmDSM Des Moines-BUF Buffalo

7h 26m1 stop Philadelphia

6:10 am - 12:31 pmBUF Buffalo-DSM Des Moines

7h 21m1 stop Philadelphia

$787American Airlines

Tue, Sep 15 - Sun, Sep 20

10:30 am - 5:18 pmDSM Des Moines-BUF Buffalo

5h 48m1 stop Chicago O'Hare Intl

6:56 pm - 12:04 amBUF Buffalo-DSM Des Moines

6h 08m1 stop Chicago O'Hare Intl

$787American Airlines

Mon, Sep 14 - Wed, Sep 16

2:25 pm - 9:15 pmDSM Des Moines-BUF Buffalo

5h 50m1 stop Denver Intl

6:00 am - 11:50 amBUF Buffalo-DSM Des Moines

6h 50m2 stops Baltimore/Washington Chicago Midway

$792Southwest

Tue, Sep 15 - Sun, Sep 20

7:00 am - 4:21 pmDSM Des Moines-BUF Buffalo

8h 21m2 stops New York LaGuardia Boston Logan Intl

5:44 pm - 11:41 pmBUF Buffalo-DSM Des Moines

6h 57m1 stop Washington, D.C. Reagan-National

$792American Airlines

Mon, Sep 14 - Wed, Sep 16

8:03 am - 5:28 pmDSM Des Moines-BUF Buffalo

8h 25m2 stops Charlotte Douglas New York LaGuardia

5:58 pm - 11:41 pmBUF Buffalo-DSM Des Moines

6h 43m2 stops New York LaGuardia Washington, D.C. Reagan-National

$798American Airlines

Tue, Sep 15 - Sun, Sep 20

7:00 am - 4:21 pmDSM Des Moines-BUF Buffalo

8h 21m2 stops New York LaGuardia Boston Logan Intl

4:55 pm - 11:41 pmBUF Buffalo-DSM Des Moines

7h 46m2 stops Boston Logan Intl Washington, D.C. Reagan-National

$798American Airlines

Tue, Sep 15 - Sun, Sep 20

8:00 am - 6:58 pmDSM Des Moines-BUF Buffalo

9h 58m3 stops Chicago O'Hare Intl Washington, D.C. Reagan-National Newark

6:10 am - 2:20 pmBUF Buffalo-DSM Des Moines

9h 10m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$889United Airlines

Fri, Sep 11 - Sun, Sep 13

6:00 am - 5:14 pmDSM Des Moines-BUF Buffalo

10h 14m1 stop Washington, D.C. Reagan-National

5:37 am - 1:43 pmBUF Buffalo-DSM Des Moines

9h 06m1 stop Washington, D.C. Reagan-National

$969American Airlines

Fri, Sep 11 - Sun, Sep 13

7:00 am - 4:21 pmDSM Des Moines-BUF Buffalo

8h 21m2 stops New York LaGuardia Boston Logan Intl

2:51 pm - 9:36 pmBUF Buffalo-DSM Des Moines

7h 45m1 stop Philadelphia

$1,002American Airlines

Fri, Sep 11 - Sun, Sep 13

7:00 am - 6:25 pmDSM Des Moines-BUF Buffalo

10h 25m2 stops Denver Intl Baltimore/Washington

8:00 am - 3:15 pmBUF Buffalo-DSM Des Moines

8h 15m2 stops Chicago Midway Denver Intl

$1,007Southwest

Booking Insights

Price, demand and travel trends for Des Moines to Buffalo flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Des Moines to Buffalo with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Des Moines to Buffalo?

Round-trip flights from Des Moines to Buffalo start at $364. Prices are typical for this route right now, with typical round-trip fares ranging from $317 to $463. The lowest price found in the past 5 days was $364 on United Airlines.

What's the cheapest day of the week to fly from Des Moines to Buffalo?

Saturday is the cheapest day of the week to fly from Des Moines to Buffalo, it is 18% cheaper than the average day. Sunday is the most expensive day with flight prices 66% higher than average. Based on deals found by KAYAK users in the last 12 months.

Find deals

Low season	February
High season	August

Best time to beat the crowds with an average 11% drop in price.

Most popular time to fly and prices are also 15% lower on average.

When to book flights from Des Moines to Buffalo

Are your dates flexible? Find out the best times to travel from Des Moines to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

Which airports can I use when flying from Des Moines to Buffalo?
Flights from Des Moines to Buffalo usually depart from Des Moines (DSM) and arrive at Buffalo (BUF).
What cabin classes can I book on flights from Des Moines to Buffalo?
Only Economy Class is available on flights from Des Moines to Buffalo.
Which airports do connecting flights from Des Moines to Buffalo pass through?
One-stop flights from Des Moines to Buffalo most commonly connect through:

• Chicago O'Hare Intl (ORD) - 53% of one-stop connections
• Detroit Metropolitan Wayne County (DTW) - 37% of one-stop connections
• Charlotte Douglas (CLT) - 3% of one-stop connections
• Chicago Midway (MDW) - 3% of one-stop connections

Chicago O'Hare Intl (ORD) handles the largest share of one-stop connections on this route.
Can I save money by using flexible dates for flights from Des Moines to Buffalo?
On the Des Moines to Buffalo route, being flexible with your departure day can save you up to 51%. Saturday is the cheapest day at $317 round-trip on average, while Sunday is the most expensive at $636: a $319 difference. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.
How long is a flight from Des Moines to Buffalo?
A nonstop flight from Des Moines to Buffalo takes 0h 00m, covering 768 miles.
Do I need a passport to fly from Des Moines to Buffalo?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.
Have flight prices from Des Moines to Buffalo changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $364 to $960. That means the highest observed fare was about 3x higher than the lowest one.
How much time can I save by choosing a different layover airport from Des Moines to Buffalo?
Flying via Chicago Midway (MDW) gives the shortest average 1-stop total travel time at 4h 14m, compared with 4h 25m via Detroit Metropolitan Wayne County (DTW) and 4h 54m via Chicago O'Hare Intl (ORD).
What is the time difference between Des Moines and Buffalo?
Buffalo is 1 hour ahead of Des Moines (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.
What car rental options are available at Buffalo Airport (BUF)?
Buffalo Airport (BUF) hosts 5 major car rental companies, with daily rates starting from around $19 for economy cars. Top options include:
• Dollar
• Budget
• Hertz
• Alamo
• Thrifty
How much should I expect to pay for a Des Moines to Buffalo flight?
Round-trip flights from Des Moines to Buffalo range from $317 to $463, with an average of $382 over the past 12 months. Anything below $317 counts as a good deal.

If your dates can be flexible, aim for a Saturday departure instead of Sunday. On this route, Saturday flights average $317 - about $319 less than Sunday (50% savings) based on the last 12 months.
If you can choose when to travel, plan your Des Moines to Buffalo trip for September. Fares historically average $317 round-trip in that month - typically $419 less than the most expensive month, which is March (based on the last 12 months).
If you're arriving late at night and need somewhere to stay, check out these hotels close to Buffalo Airport.
- Aloft Buffalo Airport
- Comfort Inn and Suites Buffalo Airport
- TownePlace Suites by Marriott Buffalo Airport

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DSM - BUF

$364 Find Cheap Flights from Des Moines to Buffalo - Compare and Save

Everything you should know

Cheap Flights from Des Moines to Buffalo (DSM-BUF)

Recent round-trip flight deals from Des Moines to Buffalo

Recent one-way flight deals from Des Moines to Buffalo

Recent last minute flight deals from Des Moines to Buffalo

Price, demand and travel trends for Des Moines to Buffalo flights

How much is a round-trip flight from Des Moines to Buffalo?

What's the cheapest day of the week to fly from Des Moines to Buffalo?

What is the cheapest airline to fly from Des Moines to Buffalo?

What is the most popular layover airport when flying from Des Moines to Buffalo?

What is the cheapest layover airport when flying from Des Moines to Buffalo?

When flying from Des Moines to Buffalo which airport offers the shortest layover?

Key details for Des Moines to Buffalo flights

Low season

High season

When to book flights from Des Moines to Buffalo

Your Des Moines to Buffalo flight questions, answered

Your guide to booking Des Moines to Buffalo flights

More options for your flight from Des Moines to Buffalo

Complete your trip to Buffalo with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Des Moines to Buffalo

Find direct flights to and from Des Moines and Buffalo

Flights from domestic origins to Buffalo

Flights to other popular destinations

Find deals for your return flight