Which airports can I use when flying from Des Moines to Buffalo?

Flights from Des Moines to Buffalo usually depart from Des Moines (DSM) and arrive at Buffalo (BUF).

What cabin classes can I book on flights from Des Moines to Buffalo?

Two cabin classes are available on flights from Des Moines to Buffalo: • Economy Class • First Class

Which airports do connecting flights from Des Moines to Buffalo pass through?

One-stop flights from Des Moines to Buffalo most commonly connect through: • Chicago O'Hare Intl (ORD) - 52% of one-stop connections • Detroit Metropolitan Wayne County (DTW) - 39% of one-stop connections • Charlotte Douglas (CLT) - 3% of one-stop connections • Chicago Midway (MDW) - 3% of one-stop connections Chicago O'Hare Intl (ORD) handles the largest share of one-stop connections on this route.

Can I save money by using flexible dates for flights from Des Moines to Buffalo?

On the Des Moines to Buffalo route, being flexible with your departure day can save you up to 51%. Saturday is the cheapest day at $317 round-trip on average, while Sunday is the most expensive at $636: a $319 difference. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

How long is a flight from Des Moines to Buffalo?

A nonstop flight from Des Moines to Buffalo takes 0h 00m, covering 768 miles.

Do I need a passport to fly from Des Moines to Buffalo?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

Have flight prices from Des Moines to Buffalo changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $325 to $716. That means the highest observed fare was about 2x higher than the lowest one.

How are flight prices from Des Moines to Buffalo looking right now?

One-way fares from Des Moines to Buffalo are currently lower than usual. Average one-way flight prices are about $224, which is 7% below the typical average for this route.

How much time can I save by choosing a different layover airport from Des Moines to Buffalo?

Flying via Chicago Midway (MDW) gives the shortest average 1-stop total travel time at 4h 14m, compared with 4h 25m via Detroit Metropolitan Wayne County (DTW) and 4h 54m via Chicago O'Hare Intl (ORD).

What is the time difference between Des Moines and Buffalo?

Buffalo is 1 hour ahead of Des Moines (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Buffalo Airport (BUF)?

Buffalo Airport (BUF) hosts 5 major car rental companies, with daily rates starting from around $19 for economy cars. Top options include: · Dollar · Budget · Hertz · Alamo · Thrifty

How much should I expect to pay for a Des Moines to Buffalo flight?

Round-trip flights from Des Moines to Buffalo range from $317 to $463, with an average of $382 over the past 12 months. Anything below $317 counts as a good deal.

What is the cheapest airline to fly from Des Moines to Buffalo?

United Airlines ($325) and American Airlines ($330) are the cheapest airlines to fly round-trip from Des Moines to Buffalo according to KAYAK data over the last 5 days.

What is the most popular layover airport when flying from Des Moines to Buffalo?

Chicago O'Hare Intl (ORD) is the most popular layover for the Des Moines to Buffalo route. 52% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via ORD.

What is the cheapest layover airport when flying from Des Moines to Buffalo?

Flights via Detroit Metropolitan Wayne County (DTW) offer the most affordable fares, with an average round-trip price of $334. Based on KAYAK data over the past 3 months.

When flying from Des Moines to Buffalo which airport offers the shortest layover?

Chicago Midway (MDW) had the shortest average connection time for Des Moines to Buffalo layovers at 164 minutes over the past 3 months.

$150 CHEAP FLIGHTS from Des Moines to Buffalo (DSM - BUF)

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Cheapest round-trip

$325

Typical prices: $317-$463

United Airlines

Sat 9/22Sat 9/29

DSM - BUF • 1 stop

Cheapest one-way

$150

Typical prices: $209-$313

Multiple Airlines

Mon 9/10

DSM - BUF • 2 stops

Nonstop flights

Not available

There are currently no direct flights between Des Moines and Buffalo. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

September

Cheapest • 17% price drop

August

Most popular

Good to know

Top layover airports

Detroit Metropolitan Wayne County (DTW)

Cheapest • Avg $334 (round-trip)

Chicago Midway (MDW)

Shortest trip • 4h 14m (one-way)

Insights

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We hope you love your trip to Buffalo!

Flight Deals

Cheap Flights from Des Moines to Buffalo (DSM-BUF)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Des Moines to Buffalo

Tue, Sep 22 - Tue, Sep 29

3:22 pm - 9:07 pmDSM Des Moines-BUF Buffalo

4h 45m1 stop Chicago O'Hare Intl

7:00 am - 12:34 pmBUF Buffalo-DSM Des Moines

6h 34m1 stop Chicago O'Hare Intl

$325United Airlines

Tue, Sep 22 - Tue, Sep 29

10:30 am - 5:18 pmDSM Des Moines-BUF Buffalo

5h 48m1 stop Chicago O'Hare Intl

5:58 pm - 12:04 amBUF Buffalo-DSM Des Moines

7h 06m2 stops New York LaGuardia Chicago O'Hare Intl

$330American Airlines

Tue, Sep 22 - Tue, Sep 29

2:44 pm - 11:54 pmDSM Des Moines-BUF Buffalo

8h 10m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

5:58 pm - 12:04 amBUF Buffalo-DSM Des Moines

7h 06m2 stops New York LaGuardia Chicago O'Hare Intl

$335American Airlines

Fri, Oct 16 - Sat, Oct 24

1:15 pm - 7:09 pmDSM Des Moines-BUF Buffalo

4h 54m1 stop Philadelphia

7:00 am - 12:45 pmBUF Buffalo-DSM Des Moines

6h 45m1 stop Philadelphia

$345American Airlines

Fri, Oct 16 - Sat, Oct 24

6:05 am - 2:27 pmDSM Des Moines-BUF Buffalo

7h 22m1 stop Philadelphia

6:33 pm - 12:14 amBUF Buffalo-DSM Des Moines

6h 41m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$350American Airlines

Thu, Nov 19 - Mon, Nov 23

6:00 am - 10:40 amDSM Des Moines-BUF Buffalo

3h 40m1 stop Chicago Midway

7:20 am - 11:30 amBUF Buffalo-DSM Des Moines

5h 10m1 stop Chicago Midway

$358Southwest

Thu, Nov 19 - Mon, Nov 23

6:00 am - 10:40 amDSM Des Moines-BUF Buffalo

3h 40m1 stop Chicago Midway

3:05 pm - 11:00 pmBUF Buffalo-DSM Des Moines

8h 55m2 stops Baltimore/Washington Chicago Midway

$363Southwest

Thu, Nov 19 - Mon, Nov 23

1:58 pm - 9:46 pmDSM Des Moines-BUF Buffalo

6h 48m1 stop Chicago O'Hare Intl

7:52 am - 1:28 pmBUF Buffalo-DSM Des Moines

6h 36m1 stop Chicago O'Hare Intl

$365American Airlines

Thu, Oct 22 - Mon, Oct 26

6:00 am - 2:24 pmDSM Des Moines-BUF Buffalo

7h 24m1 stop Washington, D.C. Reagan-National

5:50 pm - 12:14 amBUF Buffalo-DSM Des Moines

7h 24m1 stop Chicago O'Hare Intl

$365American Airlines

Thu, Nov 19 - Mon, Nov 23

7:00 am - 4:00 pmDSM Des Moines-BUF Buffalo

8h 00m2 stops Denver Intl Chicago Midway

12:40 pm - 11:00 pmBUF Buffalo-DSM Des Moines

11h 20m2 stops Tampa Chicago Midway

$368Southwest

Booking Insights

Price, demand and travel trends for Des Moines to Buffalo flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Des Moines to Buffalo with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Des Moines to Buffalo?

Round-trip flights from Des Moines to Buffalo start at $325. Prices are typical for this route right now, with typical round-trip fares ranging from $317 to $463. The lowest price found in the past 5 days was $325 on United Airlines.

What's the cheapest day of the week to fly from Des Moines to Buffalo?

Saturday is the cheapest day of the week to fly from Des Moines to Buffalo, it is 18% cheaper than the average day. Sunday is the most expensive day with flight prices 66% higher than average. Based on deals found by KAYAK users in the last 12 months.

Find deals

Low season	February
High season	August
Cheapest flight	$150

Best time to beat the crowds with an average 11% drop in price.

Most popular time to fly and prices are also 15% lower on average.

Flight from Des Moines to Buffalo

When to book flights from Des Moines to Buffalo

Are your dates flexible? Find out the best times to travel from Des Moines to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

Which airports can I use when flying from Des Moines to Buffalo?
Flights from Des Moines to Buffalo usually depart from Des Moines (DSM) and arrive at Buffalo (BUF).
What cabin classes can I book on flights from Des Moines to Buffalo?
Two cabin classes are available on flights from Des Moines to Buffalo:

• Economy Class
• First Class
Which airports do connecting flights from Des Moines to Buffalo pass through?
One-stop flights from Des Moines to Buffalo most commonly connect through:

• Chicago O'Hare Intl (ORD) - 52% of one-stop connections
• Detroit Metropolitan Wayne County (DTW) - 39% of one-stop connections
• Charlotte Douglas (CLT) - 3% of one-stop connections
• Chicago Midway (MDW) - 3% of one-stop connections

Chicago O'Hare Intl (ORD) handles the largest share of one-stop connections on this route.
Can I save money by using flexible dates for flights from Des Moines to Buffalo?
On the Des Moines to Buffalo route, being flexible with your departure day can save you up to 51%. Saturday is the cheapest day at $317 round-trip on average, while Sunday is the most expensive at $636: a $319 difference. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.
How long is a flight from Des Moines to Buffalo?
A nonstop flight from Des Moines to Buffalo takes 0h 00m, covering 768 miles.
Do I need a passport to fly from Des Moines to Buffalo?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.
Have flight prices from Des Moines to Buffalo changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $325 to $716. That means the highest observed fare was about 2x higher than the lowest one.
How are flight prices from Des Moines to Buffalo looking right now?
One-way fares from Des Moines to Buffalo are currently lower than usual. Average one-way flight prices are about $224, which is 7% below the typical average for this route.
How much time can I save by choosing a different layover airport from Des Moines to Buffalo?
Flying via Chicago Midway (MDW) gives the shortest average 1-stop total travel time at 4h 14m, compared with 4h 25m via Detroit Metropolitan Wayne County (DTW) and 4h 54m via Chicago O'Hare Intl (ORD).
What is the time difference between Des Moines and Buffalo?
Buffalo is 1 hour ahead of Des Moines (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.
What car rental options are available at Buffalo Airport (BUF)?
Buffalo Airport (BUF) hosts 5 major car rental companies, with daily rates starting from around $19 for economy cars. Top options include:
· Dollar
· Budget
· Hertz
· Alamo
· Thrifty
How much should I expect to pay for a Des Moines to Buffalo flight?
Round-trip flights from Des Moines to Buffalo range from $317 to $463, with an average of $382 over the past 12 months. Anything below $317 counts as a good deal.

If your dates can be flexible, aim for a Saturday departure instead of Sunday. On this route, Saturday flights average $317 - about $319 less than Sunday (50% savings) based on the last 12 months.
If you can choose when to travel, plan your Des Moines to Buffalo trip for September. Fares historically average $317 round-trip in that month - typically $419 less than the most expensive month, which is March (based on the last 12 months).
If you're arriving late at night and need somewhere to stay, check out these hotels close to Buffalo Airport.
- Aloft Buffalo Airport
- Comfort Inn and Suites Buffalo Airport
- TownePlace Suites by Marriott Buffalo Airport

Everything you need to know for your flight from Des Moines to Buffalo

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Des Moines (DSM)

Buffalo (BUF)

DSM - BUF

$150 Find Cheap Flights from Des Moines to Buffalo - Compare and Save

Everything you should know

Cheap Flights from Des Moines to Buffalo (DSM-BUF)

Recent round-trip flight deals from Des Moines to Buffalo

Recent one-way flight deals from Des Moines to Buffalo

Recent last minute flight deals from Des Moines to Buffalo

Price, demand and travel trends for Des Moines to Buffalo flights

How much is a round-trip flight from Des Moines to Buffalo?

What's the cheapest day of the week to fly from Des Moines to Buffalo?

What is the cheapest airline to fly from Des Moines to Buffalo?

What is the most popular layover airport when flying from Des Moines to Buffalo?

What is the cheapest layover airport when flying from Des Moines to Buffalo?

When flying from Des Moines to Buffalo which airport offers the shortest layover?

Key details for Des Moines to Buffalo flights

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High season

Cheapest flight

When to book flights from Des Moines to Buffalo

Your Des Moines to Buffalo flight questions, answered

Your guide to booking Des Moines to Buffalo flights

Everything you need to know for your flight from Des Moines to Buffalo

Information on your arrival and departure airports

Cabin class types available on flights from Des Moines to Buffalo

Complete your trip to Buffalo with a hotel stay or car rental

Find direct flights to and from Des Moines and Buffalo

Flights to other popular destinations

Flights from domestic origins to Buffalo

Choose which airport to fly into in Buffalo

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