BUF - TYS

$133 Find Cheap Flights from Buffalo to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Buffalo to Knoxville departing on 5/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Buffalo to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Buffalo to Knoxville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$298
Overall average: $283
United Airlines
Sat 5/9Tue 5/12
BUF - TYS • 1 stop
Cheapest one-way
$133
Typical prices: $159-$279
Multiple Airlines
Sat 5/9
BUF - TYS • 2 stops
Top airlines
Cheapest • from $298 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
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Airline reviews
Airline reviews
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Nonstop flights
Not available
There are currently no direct flights between Buffalo and Knoxville. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $267 (round-trip)
Shortest trip • 4h 02m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 25% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Knoxville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Buffalo to Knoxville (BUF-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Buffalo to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Buffalo to Knoxville

Sat, May 9 - Tue, May 12
United Airlines Logo
6:10 am - 10:49 am
BUF
-
TYS
4h 39m
1 stop
United Airlines Logo
7:18 pm - 11:55 pm
TYS
-
BUF
4h 37m
1 stop
$298United Airlines
Sat, May 9 - Tue, May 12
Southwest Logo
6:00 am - 3:20 pm
BUF
-
TYS
9h 20m
2 stops
Southwest Logo
8:15 am - 12:15 pm
TYS
-
BUF
4h 00m
1 stop
$303Southwest
Sat, May 9 - Tue, May 12
Southwest Logo
6:00 am - 3:20 pm
BUF
-
TYS
9h 20m
2 stops
Southwest Logo
12:50 pm - 10:15 pm
TYS
-
BUF
9h 25m
2 stops
$308Southwest
Thu, May 7 - Sun, May 10
American Airlines Logo
5:30 am - 11:01 am
BUF
-
TYS
5h 31m
1 stop
American Airlines Logo
6:00 am - 12:13 pm
TYS
-
BUF
6h 13m
1 stop
$328American Airlines
Sat, May 16 - Wed, May 20
American Airlines Logo
5:42 pm - 9:50 pm
BUF
-
TYS
4h 08m
1 stop
American Airlines Logo
6:38 pm - 11:19 pm
TYS
-
BUF
4h 41m
1 stop
$340American Airlines
Mon, Apr 13 - Mon, Apr 20
American Airlines Logo
7:28 pm - 11:55 pm
BUF
-
TYS
4h 27m
1 stop
American Airlines Logo
5:57 pm - 11:47 pm
TYS
-
BUF
5h 50m
1 stop
$348American Airlines
Mon, Apr 13 - Mon, Apr 20
Multiple Airlines Logo
12:42 pm - 10:36 am
BUF
-
TYS
45h 54m
2 stops
Multiple Airlines Logo
1:15 pm - 7:26 pm
TYS
-
BUF
6h 11m
1 stop
$354Multiple Airlines
Tue, Aug 18 - Fri, Aug 21
American Airlines Logo
5:28 pm - 9:44 pm
BUF
-
TYS
4h 16m
1 stop
American Airlines Logo
6:21 am - 11:58 am
TYS
-
BUF
5h 37m
1 stop
$357American Airlines
Tue, Aug 18 - Fri, Aug 21
Southwest Logo
9:45 am - 7:50 pm
BUF
-
TYS
10h 05m
2 stops
Southwest Logo
12:30 pm - 10:40 pm
TYS
-
BUF
10h 10m
1 stop
$368Southwest
Fri, Apr 17 - Sun, Apr 19
Multiple Airlines Logo
10:52 am - 5:30 pm
BUF
-
TYS
6h 38m
1 stop
Multiple Airlines Logo
11:27 am - 11:47 am
TYS
-
BUF
24h 20m
2 stops
$377Multiple Airlines
Booking Insights

KAYAK's insights & trends for Buffalo to Knoxville flights

Get data-powered insights and trends into flights from Buffalo to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Buffalo to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Buffalo to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Buffalo to Knoxville is August, where tickets cost $281 (return) on average. On the other hand, the most expensive months are January and December, where the average cost of round-trip tickets is $637 and $492 respectively.

Good to know

Low seasonJanuary
Cheapest flight$133
Best time to beat the crowds but there is an average 68% increase in price.
Most popular time to fly with an average 9% increase in price.
Flight from Buffalo to Knoxville

When to book flights from Buffalo to Knoxville

Are your dates flexible? Find out the best times to travel from Buffalo to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Buffalo to Knoxville

  • What is the cheapest flight from Buffalo to Knoxville?

    In the last 3 days, the lowest price for a flight from Buffalo to Knoxville was $133 for a one-way ticket and $298 for a round-trip.

  • Do I need a passport to fly between Buffalo and Knoxville?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from Buffalo to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Buffalo to Knoxville?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between Buffalo and Knoxville, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Buffalo to Knoxville, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Buffalo to Knoxville are Delta and United Airlines. With an average price for the route of $328 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $453 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Buffalo to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Buffalo to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Buffalo to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Buffalo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Buffalo to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Buffalo with another airline. Booking your flights between Buffalo and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Buffalo to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Buffalo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Buffalo to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Buffalo to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Buffalo to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8293 reviews
8.1Boarding
8.5Crew
7.8Entertainment
7.9Comfort
7.2Food
Airline reviews

Love delta smaller commuter plane so no entertainment and paid wifi on MKE-LGA leg was extremely unreliable and slow

8.0 ExcellentMary, Mar 2026
LGA - MKE
Read more Delta reviews

Love delta smaller commuter plane so no entertainment and paid wifi on MKE-LGA leg was extremely unreliable and slow

Delayed. Hot. Passenger next to me was so large I couldn’t move.

Same experience as the flight from Norfolk to Atlanta where people are boarded in zones that don't make sense. People behind you on the plane will get on before you and they take the luggage space on your row.

The flight went very well, but the flight attendants didn't serve and food or drinks other than 1st class due to rough air but to be honest it wasn't that bumpy and I felt that they could've at least offered water and coffee perhaps. Also serving 1st class only is a bad look. I've been in 1st class many times and I would've felt that if the turbulence was too rough for the main cabin, it would be too rough for 1st class too.

There was an unruly family behind us that made the short flight miserable!!! The cabin crew did nothing to contain it.

My seatback screen didn’t work so that sucked because that’s what I was going to do on the plane.

The whole experience was excellent. As it most often is with Delta

There’s not much to say about a one hour flight. This is a connection from LA to RNO that I missed the previous night due to a mechanical check delay on my originating flight from JFK to LAX. The short flight itself was fine. Instructions from the pilot and crew were per usual. The coffee was barely lukewarm, which possibly was purposeful so we would down it quickly. Bags were already on carousel upon reaching baggage claim, which was excellent.

Boarding and crew were fantastic, but I paid for a window seat with no window. Seat 11D on a CRJ-900 apparently does not have a window. Lesson learned.

Delta flights recently are always delayed AND at jfk tney get the gates further away (need To walk 20’ to get to them/all the way at the end of the terminal). Not sure whats happening but price doesnt match experience!

Everything was on time and service on the flight was great!

Wifi Bluetooth features for watching in flight movie was horrible. Screen kept blacking out no connection of sound although it said connected. Other than that smooth trip .

The travel company that you have on your site did me so wrong. I don’t know how it happened, but they put my son‘s name on my plane ticket flying to Vietnam. Along with his birthday. They would not have let me fly from Fort Myers to Ho Chi Minh City. I don’t think that I can ever use your service again. I typed my information into the browser along with my passport number and four days before I’m leaving I have to quickly search another ticket to fly out here.

Seats are uncomfortable. This has been a trend in the industry for decades. Trying to fit more seats on each plane to increase profits at the expense of the passenger.

The flight was delayed so we were dead tired, and after that the turbulence was horrible. I was very scared.

It’s always a great time flying with united airlines.

Good flight. Efficient boarding and competent flight crew. No problems until we arrived at our destination gate. We were early so there was an aircraft at the gate that had to move before we could pull in. Then, due to the type of aircraft we flew, the cabin door could not be opened until some luggage from the cargo bay was offloaded to preserve center of gravity characteristics. So, that further delayed deplaning. Despite being 20 minutes early on landing, we ended up being 5 to 10 minutes late after all the delays.

Everything went well except the turbulence what no one have a control of but pilot and crew handled very good!

There was no WiFi available, there were mechanical problems with the plane and we landed at C 124, then the gate was switched to A 26, then all the way back to C126! For a 75 yo woman traveling alone, this was a difficult journey, indeed!

This trip did not start off well. The inbound flight was delayed about 20 minutes. Then, after initial onboarding, the passengers had to deplane due to a mechanical problem. That took about 30 minutes to fix and be cleared. Then, reboarding was chaotic. It took a long time to sort passengers and two passengers on standby were ticketed but there was no seat. So, they had to deplane. One of the flight crew was trying to help passengers figure out a place to put their carry-on bags and that took more time. In the end, our scheduled 10:30 am departure did not actually take off until about 12:05 pm CST. The flight itself was long but we got to Houston. Some passengers missed their connecting flights and had to rebook. Not the best of flights I've had.

There was no inflight service. Once we landed we were delayed to find a gate for an hour and a half which was 1/2 the total time in the air.

Snow delayed boarding several times, which I understand happens. Issue I had was that after we did board, pilot told us we were going to roll out to be de-iced, then on our way. We were de-iced once, taxied to the tarmac and then stopped. Sat for another 30 minutes or so, the another de-icing. Then we rolled out to a parking spot, only to sit for another hour due to a traffic stop in DCA, which I'm confident they knew would happen before we boarded. Pilot gave no updates other than we had to hold, attendants did speak to the crew, but when asked, said the pilot would be updating us. We on the ground in the plane waiting for over 2 hours. They did communicate that bathrooms would be open, but no other news until we left. Would have been better to be up front about status.

It was good experience this time. The flight was on time.

Arrived early picked up my bag in a few minutes- great trip - thank you

The gate agent had a really bad attitude and refused to help me get on the standby list. She just handed me a card and said I needed to call a number. I asked her to help with the AA app on my phone and she just shrugged and said she didnt know. After a few phone calls, I eventually just went to a different gate agent on the other side of the terminal and got the help I needed.

One day, I do so hope for a gluten free snack! Seems like with the rest of the world FINALLY figuring out what gluten free is, American Airlines would too. Fingers crossed!!

Flight was smooth, quick and felt safe. The 2 delays not happening would have been better but I guess that happens in the airline industry

I would like the crew to talk LESS over the PA and specifically about credit card offers. I am trying to work, sleep, watch a movie and the PA was booming about a credit card offer. Could we go back to the days when the customer was more important than selling a credit card?

My seat tv didn’t work the whole trip. And the seat space is too small despite being seated at the front.

On the plus side, crew was attentive, drinks were cold, and in-flight entertainment selection was better than some other airlines. On the negative aide, Plane was delayed almost an hour, either no announcements from the gate crew. Biscoff cookies are gross, appreciate airlines that give a choice. Also, crew had no personality or enthusiasm at all.

Everything you need to know for your flight from Buffalo to Knoxville

Information on your arrival and departure airports