BUF - TYS

$89 Find Cheap Flights from Buffalo to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Buffalo to Knoxville departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Buffalo to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Buffalo to Knoxville, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Buffalo to Knoxville (BUF-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Buffalo to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Buffalo to Knoxville

Sat, Feb 21 - Wed, Feb 25
Delta Logo
6:25 am - 11:47 amBUF-TYS
5h 22m1 stop
Delta Logo
12:00 pm - 5:35 pmTYS-BUF
5h 35m1 stop
$251Delta
Find Deal
Sat, Mar 28 - Wed, Apr 1
Southwest Logo
5:15 am - 1:10 pmBUF-TYS
7h 55m2 stops
Southwest Logo
6:35 am - 4:00 pmTYS-BUF
9h 25m2 stops
$304Southwest
Find Deal
Sat, Mar 28 - Wed, Apr 1
Southwest Logo
12:25 pm - 10:10 pmBUF-TYS
9h 45m1 stop
Southwest Logo
6:35 am - 4:00 pmTYS-BUF
9h 25m2 stops
$325Southwest
Find Deal
Sat, Feb 21 - Wed, Feb 25
American Airlines Logo
11:24 am - 6:12 pmBUF-TYS
6h 48m2 stops
American Airlines Logo
6:35 am - 10:59 amTYS-BUF
4h 24m1 stop
$326American Airlines
Find Deal
Sat, Feb 21 - Wed, Feb 25
United Airlines Logo
6:00 am - 1:20 pmBUF-TYS
7h 20m2 stops
United Airlines Logo
6:45 am - 2:13 pmTYS-BUF
7h 28m2 stops
$331United Airlines
Find Deal
Thu, Dec 4 - Mon, Dec 8
Delta Logo
12:10 pm - 6:52 pmBUF-TYS
6h 42m1 stop
Delta Logo
7:59 pm - 11:59 pmTYS-BUF
4h 00m1 stop
$337Delta
Find Deal
Thu, Dec 4 - Mon, Dec 8
American Airlines Logo
11:39 am - 6:09 pmBUF-TYS
6h 30m2 stops
American Airlines Logo
7:23 pm - 11:24 pmTYS-BUF
4h 01m1 stop
$392American Airlines
Find Deal
Tue, Nov 11 - Sat, Nov 15
Delta Logo
6:00 am - 12:09 pmBUF-TYS
6h 09m1 stop
Delta Logo
5:36 pm - 11:50 pmTYS-BUF
6h 14m1 stop
$397Delta
Find Deal
Tue, Nov 11 - Sat, Nov 15
United Airlines Logo
2:55 pm - 8:20 pmBUF-TYS
5h 25m1 stop
United Airlines Logo
2:25 pm - 10:58 pmTYS-BUF
8h 33m2 stops
$402United Airlines
Find Deal
Tue, Nov 11 - Sat, Nov 15
United Airlines Logo
12:17 pm - 10:55 pmBUF-TYS
10h 38m2 stops
United Airlines Logo
2:25 pm - 10:58 pmTYS-BUF
8h 33m2 stops
$407United Airlines
Find Deal

Everything you should know

Top airlines
Delta
Cheapest • from $251 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
2 weeks
in advance
Our data shows that travelers who book at least 2 weeks in advance save around 14% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
February
Cheapest • 19% price drop
October
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$251
Overall average: $278
Delta
Sat 2/21Wed 2/25
BUF - TYS • 1 stop
Cheapest one-way
$89
Typical prices: $153-$200
Multiple Airlines
Sun 11/16
BUF - TYS • 1 stop
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Knoxville!
Booking Insights

KAYAK's insights & trends for Buffalo to Knoxville flights

Get data-powered insights and trends into flights from Buffalo to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Buffalo to Knoxville?

The average price of all round-trip flights from Buffalo to Knoxville clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Buffalo to Knoxville, look for departures on Tuesdays and avoid leaving on a Monday, as it's usually the priciest day. When flying back from Knoxville, Wednesday is the cheapest day to fly and Monday is the most expensive.

What is the cheapest month to fly from Buffalo to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Buffalo to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Buffalo to Knoxville is February, where tickets cost $278 (return) on average. On the other hand, the most expensive months are October and June, where the average cost of round-trip tickets is $393 and $388 respectively.

How far in advance should I book a flight from Buffalo to Knoxville?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Buffalo to Knoxville, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Buffalo to Knoxville, you should book around 2 weeks before departure, which saves you about 14% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 13 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$89
Best time to beat the crowds with an average 1% drop in price.
Most popular time to fly with an average 14% increase in price.
Flight from Buffalo to Knoxville

When to book flights from Buffalo to Knoxville

Are your dates flexible? Find out the best times to travel from Buffalo to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Buffalo to Knoxville

  • What is the cheapest flight from Buffalo to Knoxville?

    In the last 3 days, the lowest price for a flight from Buffalo to Knoxville was $89 for a one-way ticket and $251 for a round-trip.

  • Do I need a passport to fly between Buffalo and Knoxville?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from Buffalo to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Buffalo to Knoxville?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between Buffalo and Knoxville, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Buffalo to Knoxville, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Buffalo to Knoxville are Delta and United Airlines. With an average price for the route of $323 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $415 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Buffalo to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Buffalo to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Buffalo to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Buffalo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Buffalo to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Buffalo with another airline. Booking your flights between Buffalo and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Buffalo to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Buffalo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Buffalo to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Buffalo to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Buffalo to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7992 reviews
8.5Crew
7.9Comfort
7.3Food
7.9Entertainment
8.2Boarding
Airline reviews

The flight was great. The gate location was way to far away!!!

10.0 ExcellentLauren, Oct 2025JFK - PBI
Read more Delta reviews

The flight was great. The gate location was way to far away!!!

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

I believe that a four-hour trip should have a meal. Delta had none.

Was charged for my luggage despite having been on one ticket from an international flight. Too tired to argue after 15 hours on flight. Was charged for rechecking it at JFK airport. Not sure why those off Kenya Airways were required to do that.

My experience on any Delta flight is always overshadowed by the time Delta removed me from a flight for no apparent reason.

Flight was canceled, and no effort was made to help with rebooking, no hotel vouchers, no car transportation and minimal food voucher and most places for food were closed by the time the voucher was given. Waited for 3 hours for bags. Simply the worst travel experience I have ever had

At first, we were on the runway for about an hour, literally. The Captain did explain that the Control Tower just had a change shift (sounds like an unrealistic excuse) and then that we had to change a runway. A regular economy seat is made for 12 yo twiggy. I understand Delta wants to push for an upgrade, but after sitting in a Comfort seat and in First class. I would say First class is not worthy of my money. The landing was delayed because of the weather in NYC, I don't hold that against Delta, of course. The Captain did alert us to that upon takeoff in Vegas and again as we reached NY.

Not a "Delta" issue, but a JFK issue: We booked a connecting flight with 3 1/2 hours between to clearn immigration and customs. Our inbound flight (BCN to JFK) was on the taxiway 45 minutes which ate into our layover time. Immigtration was insanely quick with the CBP MPC app; however, clearing TSA (again, after we were ALREADY cleared in Spain on the inbound international flight) took over 95 minutes. This left us with 10 minutes before boarding the connecting flight (JFK to SAN) to walk to the far end of Terminal 4 and try to find food. We didn't find any food that could promise to serve us in under 10 minutes so we boarded the Delta flight after coming off a plance and an 8-hour flight knowing that we wouldn't be served any food on the next 5 1/2 hour flight. I feel like Delta needs to put pressure on the JFK TSA to open more screening stations (by our count, we saw only 5 scanners open and a line of - as we said - over 90 minutes. The insult is that we WERE ALREADY SCREENED through TSA, but as you come off one flight into the USA, you have to go through the whole process again. It seems like if you have a connecting flight, there should be a way to pass through immigration and customs without needing to return through TSA.

My flight was 6 pm 6/6. Every hour they delayed it again - air condition issues then no pilot then the crew had worked too many hours and cancelled the flight at 11 pm. Sent customers to NJ a 45 minutes uber ride to a hotel. Had to be back by 5 am for a 7 am flight and again no pilot etc with another three hours of delays.

Flight was delayed only slightly before takeoff due to traffic control. However, the flight arrived early to ORD. Good flight. United has been very reliable for me.

The person I bought the ticket for didn’t make the flight.

Lately I like the planes have been exceptionally filthy. There’s lines of dust and dirt all across the ceiling in the vents, and the cracks in between the seats are literally full of food. It’s definitely not the quality of service that I was used to with United. I’m also very disappointed with the Wi-Fi! All I wanna do is knock out a few work jobs while I’m trapped in my seat And it spools so bad. They did provide me with a refund, but the process of getting that refund is so complicated. It’s unfortunate.

Another delayed flight. When the delays exceed the duration of the flight, it’s a problem.

Excellent flight. Smooth, efficient boarding. Quick flight. Arrived early at STL.

After boarding the plane in Chicago, the passengers were told that there was a technical problem with the plane. Passengers remained on the plane as they tried to fix the problem. After what was probably an hour passengers were told that there was a need to change planes as the problem was not solved. Passengers disembarked and boarded another plane. After taxing to the runway and waiting for takeoff, passengers were told that owing to the thunderstorm the flight was unable to take off but would try and reroute. After some time passengers were told there wasn't enough fuel for the new route and the plane had to return to the gate for additional fuel. after another log delay the flight got underway. On the plane there was food, drinks, ice or entertainment. We were a glass of water, which appeared rationed. Flight arrived about 5 hours late. The pilot was fantastic and communicated with the passengers throughout the ordeal.

The flight attendants were great, I joked with one I can’t remember her name, a blond, really sweet. I thought it was run well very professional. This was great i survived Spirit, I know for which I speak.

During booking, I kept trying submitting my payment from the Mexican website and it didn't work. After I had the idea to change it to the Canadian website, it worked but I had to be charged the equivalent of 50 CAD more. I received the clear instruction that I would only be able to check-in at the airport and that it was impossible to select a seat 24 hours before departure, that I had to pay 144 CAD to do so, although not only was I able to check-in 24 hours before departure, but I could have selected my seats for free then. All in all, I almost threw $200 out the window due to misleading information. Besides, the app kept crashing, the information to get to the gate on the app was inaccurate, my gate was switched and I was only informed once in the air (luckily I had noticed the departure pannel), I was not addressed in my language beforehand and even if I tried I was immediately answered in English (which meant the crew understood but didn't want to answer accordingly), there was only one snack & beverage service on my medium haul flight and no beverage service on my short haul flight. To be fair, the planes were comfortable, the crew apart from the language issue was helpful, dynamic and engaging, the plane was clean and the directions were clear and direct. United has a lot of potential to be one of my favourite airlines, but the devil is in the details and a lot of them missed the target.

Flight was timely, relatively comfortable, with decent entertainment and food served. Only problem encountered was with the free messaging which I highly appreciate, but it did not work from iphone to non-iphones.

Better WiFi. I cannot understand that in 2025, United is so behind on a technology that is now a necessity and still painfully unreliable, slow and keeps disconnecting.

They only offered water for Group 6. Awful announcements from the Crew. Couldn't understand a single word. Barely came by for the trash afterwards. Man, I love water for a premium flight. Wow. Water in a cup.

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

The comfort of the seats was great, the crew eased my child’s anxieties and the fact that I had full cans of my beverage choice was great.

Crew should be nicer and emphatic with customers. Same cookies as the past 20 years. Seat are ok and the plane was clean though it was delayed.

Plane was delayed for 6 hours, at first by weather, which is understandable, but was further delayed with NO given reason for 2 1/2 hours more. We had no clue when we were going to depart actually until they opened the ramp. VERY POOR to ZERO COMMUNICATION!!!

Delayed because of weather in Nashville. I think God or some higher power generally has cursed me when it comes to flying out of Charlotte on American. I'm delayed pretty much everytime. We need Team Cobra Kai types to come in and "sweep the leg(s)" of the Charlotte ops people on principle. Don't let the sweet southern rocking chairs fool you, Charlotte is a sinkhole

Waited on the runway for takeoff for 2.5 hours. Air traffic rerouted us. The plane didn't have enough fuel, so had to go back to the gate. Had to wait for a new pilot. Should have landed at 5:22. Didn't land until 9:10. Trash flight.

There were five broken seats on the plane. The crew was very rude in telling people they had to get off the plane and get a flight the next day. No call for volunteers, but telling people they had to get off. One woman was flying with her elderly mother and daughter and was told she had to leave or all three had to leave. Fortunately, a volunteer offered to stay. The situation was handled poorly.

At least it was a short flight. Greyhound with wings.

late again! but its my only option to not take 9 hours to get to Memphis

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