Which airports can I use when flying from Knoxville to Buffalo?

Flights from Knoxville to Buffalo usually depart from Knoxville McGhee Tyson (TYS) and arrive at Buffalo (BUF).

What cabin classes can I book on flights from Knoxville to Buffalo?

Two cabin classes are available on flights from Knoxville to Buffalo: • Economy Class • First Class

Which airports do connecting flights from Knoxville to Buffalo pass through?

One-stop flights from Knoxville to Buffalo most commonly connect through: • Baltimore/Washington (BWI) - 33% of one-stop connections • Charlotte Douglas (CLT) - 23% of one-stop connections • Washington, D.C. Reagan-National (DCA) - 18% of one-stop connections • Detroit Metropolitan Wayne County (DTW) - 10% of one-stop connections

Can I save money by using flexible dates for flights from Knoxville to Buffalo?

Yes. Flexible dates can save you up to 43% on flights from Knoxville to Buffalo. Saturday is the cheapest departure day at $286 round-trip on average, while Sunday is the most expensive at $496, a difference of $210. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

How long is a flight from Knoxville to Buffalo?

A nonstop flight from Knoxville to Buffalo takes 00m, covering 567 miles.

Do I need a passport to fly from Knoxville to Buffalo?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Have flight prices from Knoxville to Buffalo changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $253 to $770. That means the highest observed fare was about 3x higher than the lowest one.

How are flight prices from Knoxville to Buffalo looking right now?

One-way fares from Knoxville to Buffalo are currently in line with typical prices for this route. Average one-way fares are about $305.

How much time can I save by choosing a different layover airport from Knoxville to Buffalo?

Flying via Detroit Metropolitan Wayne County (DTW) gives the shortest average 1-stop total travel time at 3h 46m, compared with 4h 08m via Washington, D.C. Dulles Intl (IAD) and 4h 16m via Charlotte Douglas (CLT).

What car rental options are available at Buffalo Airport (BUF)?

Buffalo Airport (BUF) hosts 5 major car rental companies, with daily rates averaging $82 for economy cars. Top options include: • Dollar • Budget • Hertz • Thrifty • Alamo

How much should I expect to pay for a Knoxville to Buffalo flight?

Round-trip flights from Knoxville to Buffalo range from $351 to $481, with an average of $396 over the past 12 months. Anything below $351 counts as a good deal.

How much is a round-trip flight from Knoxville to Buffalo?

Round-trip flights from Knoxville to Buffalo typically range from $351 to $481. The lowest price found in the past 5 days was $253, on American Airlines.

What's the cheapest day of the week to fly from Knoxville to Buffalo?

Based on deals KAYAK users found in the last 12 months, Saturday is the cheapest day of the week to fly from Knoxville to Buffalo. It’s 28% cheaper than the average day, while Sunday is the most expensive, with prices 25% higher.

What’s the cheapest month to fly from Knoxville to Buffalo?

•November is the cheapest month to fly from Knoxville to Buffalo at $268 round-trip. •December ($798) and March ($682) are the most expensive months. •The price difference between flying in the cheapest and most expensive months is 197% on average. This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Which airline is the cheapest to fly from Knoxville to Buffalo?

American Airlines ($253) and Delta ($253) are the cheapest airlines to fly round-trip from Knoxville to Buffalo according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from Knoxville to Buffalo?

Baltimore/Washington (BWI) is the most popular layover for the Knoxville to Buffalo route. 33% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via BWI.

What is the cheapest layover airport when flying from Knoxville to Buffalo?

Flights via Atlanta Hartsfield-Jackson (ATL) offer the most affordable fares, with an average round-trip price of $326. Based on KAYAK data over the past 3 months.

When flying from Knoxville to Buffalo which airport offers the shortest layover?

Detroit Metropolitan Wayne County (DTW) had the shortest average connection time for Knoxville to Buffalo layovers at 2h 19m over the past 3 months.

$147 CHEAP FLIGHTS from Knoxville to Buffalo (TYS - BUF)

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Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$253

Typical prices: $351-$481

American Airlines

Wed 12/12Sat 12/15

TYS - BUF • 1 stop

Cheapest one-way

$147

Typical prices: $203-$323

United Airlines

Tue 11/20

TYS - BUF • 1 stop

Nonstop flights

Not available

There are currently no direct flights between Knoxville and Buffalo. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

November

Cheapest • 32% price drop

June

Most popular

Good to know

Top layover airports

Atlanta Hartsfield-Jackson (ATL)

Cheapest • Avg $326 (round-trip)

Detroit Metropolitan Wayne County (DTW)

Shortest trip • 3h 46m (one-way)

Insights

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We hope you love your trip to Buffalo!

Flight Deals

Cheap Flights from Knoxville to Buffalo (TYS-BUF)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Knoxville to Buffalo

Sat, Dec 12 - Tue, Dec 15

12:42 pm - 6:25 pmTYS Knoxville McGhee Tyson-BUF Buffalo

5h 43m1 stop Philadelphia

6:52 pm - 10:53 pmBUF Buffalo-TYS Knoxville McGhee Tyson

4h 01m1 stop Charlotte Douglas

$253American Airlines

Tue, Dec 1 - Wed, Dec 9

6:13 pm - 12:05 amTYS Knoxville McGhee Tyson-BUF Buffalo

5h 52m1 stop Washington, D.C. Reagan-National

12:12 pm - 5:56 pmBUF Buffalo-TYS Knoxville McGhee Tyson

5h 44m1 stop Washington, D.C. Reagan-National

$253American Airlines

Tue, Dec 1 - Tue, Dec 8

11:07 am - 5:30 pmTYS Knoxville McGhee Tyson-BUF Buffalo

6h 23m1 stop New York LaGuardia

12:11 pm - 6:56 pmBUF Buffalo-TYS Knoxville McGhee Tyson

6h 45m1 stop Atlanta Hartsfield-Jackson

$253Delta

Sat, Dec 12 - Tue, Dec 15

5:40 am - 11:05 amTYS Knoxville McGhee Tyson-BUF Buffalo

5h 25m1 stop Atlanta Hartsfield-Jackson

12:06 pm - 6:22 pmBUF Buffalo-TYS Knoxville McGhee Tyson

6h 16m1 stop Detroit Metropolitan Wayne County

$253Delta

Wed, Dec 9 - Mon, Dec 14

7:10 am - 11:24 amTYS Knoxville McGhee Tyson-BUF Buffalo

4h 14m1 stop Detroit Metropolitan Wayne County

12:06 pm - 6:22 pmBUF Buffalo-TYS Knoxville McGhee Tyson

6h 16m1 stop Detroit Metropolitan Wayne County

$253Delta

Sat, Dec 12 - Tue, Dec 15

6:00 am - 1:17 pmTYS Knoxville McGhee Tyson-BUF Buffalo

7h 17m1 stop Chicago O'Hare Intl

7:00 am - 2:53 pmBUF Buffalo-TYS Knoxville McGhee Tyson

7h 53m2 stops Newark Washington, D.C. Dulles Intl

$258United Airlines

Sat, Dec 12 - Tue, Dec 15

6:00 am - 2:20 pmTYS Knoxville McGhee Tyson-BUF Buffalo

8h 20m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

6:00 am - 2:53 pmBUF Buffalo-TYS Knoxville McGhee Tyson

8h 53m2 stops Newark Washington, D.C. Dulles Intl

$263United Airlines

Tue, Dec 1 - Tue, Dec 8

1:00 pm - 10:25 pmTYS Knoxville McGhee Tyson-BUF Buffalo

9h 25m1 stop Orlando

7:25 am - 4:40 pmBUF Buffalo-TYS Knoxville McGhee Tyson

9h 15m2 stops Baltimore/Washington Orlando

$264Southwest

Wed, Dec 9 - Mon, Dec 14

7:55 am - 12:05 pmTYS Knoxville McGhee Tyson-BUF Buffalo

4h 10m1 stop Baltimore/Washington

11:20 am - 7:50 pmBUF Buffalo-TYS Knoxville McGhee Tyson

8h 30m2 stops Orlando Nashville Intl

$299Southwest

Fri, Dec 25 - Wed, Dec 30

6:30 am - 10:56 amTYS Knoxville McGhee Tyson-BUF Buffalo

4h 26m1 stop Philadelphia

7:15 am - 2:19 pmBUF Buffalo-TYS Knoxville McGhee Tyson

7h 04m1 stop Philadelphia

$303American Airlines

Recent last minute flight deals from Knoxville to Buffalo

Tue, Nov 3 - Wed, Nov 11

4:59 pm - 9:37 pmTYS Knoxville McGhee Tyson-BUF Buffalo

4h 38m1 stop Chicago O'Hare Intl

12:58 pm - 4:48 pmBUF Buffalo-TYS Knoxville McGhee Tyson

3h 50m1 stop Charlotte Douglas

$629American Airlines

Tue, Nov 3 - Wed, Nov 11

1:55 pm - 7:04 pmTYS Knoxville McGhee Tyson-BUF Buffalo

5h 09m1 stop Washington, D.C. Dulles Intl

6:00 am - 2:48 pmBUF Buffalo-TYS Knoxville McGhee Tyson

8h 48m2 stops Newark Washington, D.C. Dulles Intl

$634United Airlines

Tue, Nov 3 - Wed, Nov 11

1:00 pm - 9:55 pmTYS Knoxville McGhee Tyson-BUF Buffalo

8h 55m2 stops Orlando Baltimore/Washington

11:20 am - 8:50 pmBUF Buffalo-TYS Knoxville McGhee Tyson

9h 30m2 stops Orlando Baltimore/Washington

$639Southwest

Mon, Nov 2 - Fri, Nov 6

4:59 pm - 9:37 pmTYS Knoxville McGhee Tyson-BUF Buffalo

4h 38m1 stop Chicago O'Hare Intl

6:00 am - 11:16 amBUF Buffalo-TYS Knoxville McGhee Tyson

5h 16m1 stop Philadelphia

$717American Airlines

Sun, Nov 1 - Mon, Nov 2

4:30 pm - 10:59 pmTYS Knoxville McGhee Tyson-BUF Buffalo

6h 29m1 stop Newark

7:52 pm - 11:59 pmBUF Buffalo-TYS Knoxville McGhee Tyson

4h 07m1 stop Washington, D.C. Dulles Intl

$721United Airlines

Mon, Nov 2 - Fri, Nov 6

10:33 am - 10:59 pmTYS Knoxville McGhee Tyson-BUF Buffalo

12h 26m2 stops Chicago O'Hare Intl Newark

7:52 pm - 11:59 pmBUF Buffalo-TYS Knoxville McGhee Tyson

4h 07m1 stop Washington, D.C. Dulles Intl

$722United Airlines

Sun, Nov 1 - Mon, Nov 2

6:45 am - 7:05 pmTYS Knoxville McGhee Tyson-BUF Buffalo

12h 20m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

7:52 pm - 11:59 pmBUF Buffalo-TYS Knoxville McGhee Tyson

4h 07m1 stop Washington, D.C. Dulles Intl

$726United Airlines

Mon, Nov 2 - Fri, Nov 6

1:55 pm - 10:59 pmTYS Knoxville McGhee Tyson-BUF Buffalo

9h 04m2 stops Washington, D.C. Dulles Intl Newark

6:00 am - 3:52 pmBUF Buffalo-TYS Knoxville McGhee Tyson

9h 52m2 stops Washington, D.C. Dulles Intl Newark

$838United Airlines

Sun, Nov 1 - Mon, Nov 2

6:45 am - 2:10 pmTYS Knoxville McGhee Tyson-BUF Buffalo

7h 25m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

6:30 am - 2:48 pmBUF Buffalo-TYS Knoxville McGhee Tyson

8h 18m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$1,017United Airlines

Booking Insights

Price, demand and travel trends for Knoxville to Buffalo flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Knoxville to Buffalo? This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Knoxville to Buffalo departing in december.
What's the cheapest day of the week to fly from Knoxville to Buffalo?: Based on deals KAYAK users found in the last 12 months, Saturday is the cheapest day of the week to fly from Knoxville to Buffalo. It’s 28% cheaper than the average day, while Sunday is the most expensive, with prices 25% higher.
What’s the cheapest month to fly from Knoxville to Buffalo? KAYAK internal proprietary data takes all prices for each month over the last 12 months for round-trip flights from Knoxville to Buffalo, removes the top 0.1% to account for outliers and then takes the median of all values for each month.: •November is the cheapest month to fly from Knoxville to Buffalo at $268 round-trip.
•December ($798) and March ($682) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 197% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Low season	January
High season	June
Cheapest flight	$147

Beat the crowds with an average 64% drop in travelers.

The most popular month to fly with an average 107% increase in travelers.

One-way flight from Knoxville to Buffalo

When to book flights from Knoxville to Buffalo

Are your dates flexible? Find out the best times to travel from Knoxville to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Knoxville to Buffalo?
Two cabin classes are available on flights from Knoxville to Buffalo:

• Economy Class
• First Class
How long is a flight from Knoxville to Buffalo?
A nonstop flight from Knoxville to Buffalo takes 00m, covering 567 miles.
Do I need a passport to fly from Knoxville to Buffalo?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.
How much should I expect to pay for a Knoxville to Buffalo flight?
Round-trip flights from Knoxville to Buffalo range from $351 to $481, with an average of $396 over the past 12 months. Anything below $351 counts as a good deal.
Have flight prices from Knoxville to Buffalo changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $253 to $770. That means the highest observed fare was about 3x higher than the lowest one.
How are flight prices from Knoxville to Buffalo looking right now?
One-way fares from Knoxville to Buffalo are currently in line with typical prices for this route. Average one-way fares are about $305.
What car rental options are available at Buffalo Airport (BUF)?
Buffalo Airport (BUF) hosts 5 major car rental companies, with daily rates averaging $82 for economy cars. Top options include:

• Dollar
• Budget
• Hertz
• Thrifty
• Alamo
Which airports can I use when flying from Knoxville to Buffalo?
Flights from Knoxville to Buffalo usually depart from Knoxville McGhee Tyson (TYS) and arrive at Buffalo (BUF).
Which airports do connecting flights from Knoxville to Buffalo pass through?
One-stop flights from Knoxville to Buffalo most commonly connect through:

• Baltimore/Washington (BWI) - 33% of one-stop connections
• Charlotte Douglas (CLT) - 23% of one-stop connections
• Washington, D.C. Reagan-National (DCA) - 18% of one-stop connections
• Detroit Metropolitan Wayne County (DTW) - 10% of one-stop connections
Can I save money by using flexible dates for flights from Knoxville to Buffalo?
Yes. Flexible dates can save you up to 43% on flights from Knoxville to Buffalo. Saturday is the cheapest departure day at $286 round-trip on average, while Sunday is the most expensive at $496, a difference of $210.

Cheaper weekend fares like these are typical of routes dominated by weekday business travel.
How much time can I save by choosing a different layover airport from Knoxville to Buffalo?
Flying via Detroit Metropolitan Wayne County (DTW) gives the shortest average 1-stop total travel time at 3h 46m, compared with 4h 08m via Washington, D.C. Dulles Intl (IAD) and 4h 16m via Charlotte Douglas (CLT).

If your dates are flexible, aim for a Saturday departure and avoid flying on Sunday. On this route, Saturday flights average $286, about $210 less than Sunday fares (42% savings) based on the last 12 months.
If you can choose when to travel, plan your Knoxville to Buffalo trip for November. Fares historically average $268 round-trip in that month - typically $530 less than the most expensive month, which is December (based on the last 12 months).
If you're arriving late at night and need somewhere to stay, check out these hotels close to Buffalo Airport.

• Aloft Buffalo Airport
• Comfort Inn and Suites Buffalo Airport
• TownePlace Suites by Marriott Buffalo Airport

More options for your flight from Knoxville to Buffalo

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TYS - BUF

$147 Find Cheap Flights from Knoxville to Buffalo - Compare and Save

Everything you should know

Cheap Flights from Knoxville to Buffalo (TYS-BUF)

Recent round-trip flight deals from Knoxville to Buffalo

Recent one-way flight deals from Knoxville to Buffalo

Recent last minute flight deals from Knoxville to Buffalo

Price, demand and travel trends for Knoxville to Buffalo flights

How much is a round-trip flight from Knoxville to Buffalo?

What's the cheapest day of the week to fly from Knoxville to Buffalo?

What’s the cheapest month to fly from Knoxville to Buffalo?

Which airline is the cheapest to fly from Knoxville to Buffalo?

What’s the most popular layover airport when flying from Knoxville to Buffalo?

What is the cheapest layover airport when flying from Knoxville to Buffalo?

When flying from Knoxville to Buffalo which airport offers the shortest layover?

Key details for Knoxville to Buffalo flights

Low season

High season

Cheapest flight

When to book flights from Knoxville to Buffalo

Your Knoxville to Buffalo flight questions, answered

Your guide to booking Knoxville to Buffalo flights

More options for your flight from Knoxville to Buffalo

Complete your trip to Buffalo with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Knoxville to Buffalo

Find direct flights to and from Knoxville and Buffalo

Flights from domestic origins to Buffalo

Flights to other popular destinations

Find deals for your return flight