TYS - BUF

$136 Find Cheap Flights from Knoxville to Buffalo - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$239
Typical prices: $316-$446
Delta
Wed 10/17Sat 10/20
TYS - BUF • 1 stop
Cheapest one-way
$201
Typical prices: $168-$329
United Airlines
Tue 11/20
TYS - BUF • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Buffalo. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
November
Cheapest • 22% price drop
July
Most popular
Good to know
+1
Good to know
+1
Top layover airports
New York LaGuardia (LGA)
Cheapest • Avg $232 (round-trip)
Detroit Metropolitan Wayne County (DTW)
Shortest trip • 3h 56m (one-way)
Insights
Insights
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Flight Deals

Cheap Flights from Knoxville to Buffalo (TYS-BUF)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Buffalo

Sat, Oct 17 - Tue, Oct 20
Delta Logo
5:40 am - 11:16 amTYS  Knoxville McGhee Tyson-BUF Buffalo
5h 36m1 stop Atlanta Hartsfield-Jackson
Delta Logo
3:53 pm - 9:37 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
5h 44m1 stop Detroit Metropolitan Wayne County
$239Delta
Sat, Oct 17 - Wed, Oct 21
Delta Logo
5:40 am - 11:16 amTYS  Knoxville McGhee Tyson-BUF Buffalo
5h 36m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:15 am - 10:20 amBUF  Buffalo-TYS Knoxville McGhee Tyson
4h 05m1 stop Detroit Metropolitan Wayne County
$239Delta
Fri, Oct 16 - Tue, Oct 20
Delta Logo
6:00 am - 1:29 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
7h 29m1 stop New York LaGuardia
Delta Logo
6:00 am - 11:02 amBUF  Buffalo-TYS Knoxville McGhee Tyson
5h 02m1 stop New York LaGuardia
$271Delta
Fri, Oct 16 - Tue, Oct 20
Multiple Airlines Logo
9:41 pm - 12:59 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
15h 18m2 stops Tampa St. Petersburg Atlanta Hartsfield-Jackson
Multiple Airlines Logo
6:51 pm - 1:53 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
19h 02m1 stop Orlando
$278Multiple Airlines
Fri, Oct 16 - Mon, Oct 19
American Airlines Logo
6:00 am - 12:46 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
6h 46m1 stop Philadelphia
American Airlines Logo
7:53 pm - 11:55 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
4h 02m1 stop Charlotte Douglas
$287American Airlines
Fri, Oct 16 - Mon, Oct 19
American Airlines Logo
6:05 pm - 11:59 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
5h 54m1 stop Washington, D.C. Reagan-National
American Airlines Logo
6:00 am - 10:25 amBUF  Buffalo-TYS Knoxville McGhee Tyson
4h 25m1 stop Washington, D.C. Reagan-National
$287American Airlines
Fri, Oct 16 - Wed, Oct 21
United Airlines Logo
10:42 am - 4:43 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
6h 01m1 stop Chicago O'Hare Intl
United Airlines Logo
6:30 am - 2:42 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
8h 12m2 stops Newark Washington, D.C. Dulles Intl
$292United Airlines
Sat, Oct 17 - Wed, Oct 21
Multiple Airlines Logo
5:43 pm - 5:52 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
24h 09m1 stop Orlando Sanford Intl
Multiple Airlines Logo
1:44 pm - 11:29 amBUF  Buffalo-TYS Knoxville McGhee Tyson
21h 45m2 stops Atlanta Hartsfield-Jackson Baltimore/Washington
$313Multiple Airlines
Fri, Nov 13 - Sun, Nov 15
Southwest Logo
8:10 am - 12:00 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
3h 50m1 stop Baltimore/Washington
Southwest Logo
5:05 am - 4:50 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
11h 45m1 stop Orlando
$361Southwest
Fri, Nov 13 - Sun, Nov 15
Southwest Logo
8:10 am - 2:25 pmTYS  Knoxville McGhee Tyson-BUF Buffalo
6h 15m1 stop Baltimore/Washington
Southwest Logo
11:00 am - 8:35 pmBUF  Buffalo-TYS Knoxville McGhee Tyson
9h 35m2 stops Baltimore/Washington Nashville Intl
$361Southwest
Booking Insights

Price, demand and travel trends for Knoxville to Buffalo flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Knoxville to Buffalo with more confidence.

How much is a round-trip flight from Knoxville to Buffalo?

Round-trip flights from Knoxville to Buffalo start at $239. Prices are below average for this route right now, with typical round-trip fares ranging from $316 to $446. The lowest price found in the past 5 days was $239 on Delta.

What's the cheapest day of the week to fly from Knoxville to Buffalo?

Saturday is the cheapest day of the week to fly from Knoxville to Buffalo, it is 21% cheaper than the average day. Friday is the most expensive day with flight prices 37% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Knoxville to Buffalo?

•November is the cheapest month to fly from Knoxville to Buffalo at $283 round-trip.
•December ($798) and March ($682) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 181% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Knoxville to Buffalo flights

Low season

January

Cheapest flight

$201
Best time to beat the crowds but there is an average 79% increase in price.
Most popular time to fly with an average 6% increase in price.
Flight from Knoxville to Buffalo

When to book flights from Knoxville to Buffalo

Are your dates flexible? Find out the best times to travel from Knoxville to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Knoxville to Buffalo flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Knoxville to Buffalo?

    Flights from Knoxville to Buffalo usually depart from Knoxville McGhee Tyson (TYS) and arrive at Buffalo (BUF).

  • What cabin classes can I book on flights from Knoxville to Buffalo?

    Two cabin classes are available on flights from Knoxville to Buffalo:

    • Economy Class
    • First Class

  • Which airports do connecting flights from Knoxville to Buffalo pass through?

    One-stop flights from Knoxville to Buffalo most commonly connect through:

    • Charlotte Douglas (CLT) - 26% of one-stop connections
    • Baltimore/Washington (BWI) - 23% of one-stop connections
    • Washington, D.C. Reagan-National (DCA) - 13% of one-stop connections
    • Detroit Metropolitan Wayne County (DTW) - 13% of one-stop connections

    Charlotte Douglas (CLT) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Knoxville to Buffalo?

    On the Knoxville to Buffalo route, being flexible with your departure day can save you up to 43%. Saturday is the cheapest day at $286 round-trip on average, while Friday is the most expensive at $498: a $212 difference. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

  • How long is a flight from Knoxville to Buffalo?

    A nonstop flight from Knoxville to Buffalo takes 0h 00m, covering 567 miles.

  • Do I need a passport to fly from Knoxville to Buffalo?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Knoxville to Buffalo changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $239 to $1,278. That means the highest observed fare was about 5x higher than the lowest one.

  • How are flight prices from Knoxville to Buffalo looking right now?

    One-way fares from Knoxville to Buffalo are currently higher than usual. Average one-way flight prices are about $387, which is 39% above the typical average for this route.

  • How much time can I save by choosing a different layover airport from Knoxville to Buffalo?

    Flying via Detroit Metropolitan Wayne County (DTW) gives the shortest average 1-stop total travel time at 3h 56m, compared with 3h 58m via Washington, D.C. Dulles Intl (IAD) and 4h 16m via Charlotte Douglas (CLT).

  • What car rental options are available at Buffalo Airport (BUF)?

    Buffalo Airport (BUF) hosts 5 major car rental companies, with daily rates starting from around $19 for economy cars. Top options include:
    • Dollar
    • Budget
    • Hertz
    • Alamo
    • Thrifty

  • How much should I expect to pay for a Knoxville to Buffalo flight?

    Round-trip flights from Knoxville to Buffalo range from $316 to $446, with an average of $362 over the past 12 months. Anything below $316 counts as a good deal.

Your guide to booking Knoxville to Buffalo flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Saturday departure instead of Friday. On this route, Saturday flights average $286 - about $212 less than Friday (43% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Knoxville to Buffalo trip for November. Fares historically average $283 round-trip in that month - typically $515 less than the most expensive month, which is December (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Buffalo Airport.
    - Aloft Buffalo Airport
    - Comfort Inn and Suites Buffalo Airport
    - TownePlace Suites by Marriott Buffalo Airport

More options for your flight from Knoxville to Buffalo

Complete your trip to Buffalo with a hotel stay or car rental

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