$417 Find Cheap Flights from the Cayman Islands to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Francisco departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results for flights to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results for flights to San Francisco, as well as popular online travel agencies
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Cheap Flights from the Cayman Islands to San Francisco

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from the Cayman Islands to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from the Cayman Islands to San Francisco

Fri, Oct 24 - Tue, Oct 28
American Airlines Logo
8:25 am - 10:59 pmGCM-SFO
16h 34m1 stop
American Airlines Logo
11:36 pm - 11:20 amSFO-GCM
9h 44m1 stop
$575American Airlines
Find Deal
Fri, Oct 24 - Tue, Oct 28
American Airlines Logo
8:25 am - 9:56 pmGCM-SFO
15h 31m2 stops
American Airlines Logo
11:36 pm - 1:10 pmSFO-GCM
11h 34m2 stops
$579American Airlines
Find Deal
Mon, Aug 11 - Wed, Sep 24
 Logo
4:45 pm - 8:47 pmGCM-SFO
30h 02m2 stops
 Logo
1:30 pm - 2:45 pmSFO-GCM
23h 15m1 stop
Thu, Aug 14 - Wed, Sep 24
 Logo
4:45 pm - 12:15 pmGCM-SFO
21h 30m2 stops
 Logo
1:30 pm - 2:45 pmSFO-GCM
23h 15m1 stop
Mon, Aug 11 - Wed, Sep 24
Air Canada Logo
12:50 pm - 6:43 pmGCM-SFO
31h 53m2 stops
Air Canada Logo
1:05 pm - 11:55 amSFO-GCM
20h 50m2 stops
$689Air Canada
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Mon, Aug 11 - Tue, Sep 23
Air Canada Logo
12:50 pm - 9:25 amGCM-SFO
22h 35m2 stops
Air Canada Logo
4:35 pm - 11:55 amSFO-GCM
41h 20m2 stops
$710Air Canada
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Sat, Sep 13 - Fri, Sep 19
United Airlines Logo
1:35 pm - 11:38 amGCM-SFO
24h 03m1 stop
United Airlines Logo
12:43 am - 12:30 pmSFO-GCM
9h 47m1 stop
$791United Airlines
Find Deal
Thu, Aug 14 - Fri, Sep 26
United Airlines Logo
1:35 pm - 5:45 pmGCM-SFO
30h 10m1 stop
United Airlines Logo
12:43 am - 12:30 pmSFO-GCM
9h 47m1 stop
$816United Airlines
Find Deal
Fri, Aug 15 - Sun, Sep 21
Delta Logo
12:52 pm - 12:35 amGCM-SFO
13h 43m1 stop
Delta Logo
9:38 pm - 11:36 amSFO-GCM
11h 58m1 stop
$831Delta
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Thu, Aug 14 - Wed, Sep 24
Delta Logo
12:52 pm - 12:35 amGCM-SFO
13h 43m1 stop
Delta Logo
11:57 pm - 11:36 amSFO-GCM
9h 39m1 stop
$840Delta
Find Deal
Booking Insights

KAYAK's insights & trends for flights to San Francisco

Get data-powered insights and trends for flights to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights to San Francisco is February, where tickets cost $254 on average for return flights. On the other hand, the most expensive months are October and July, where the average cost of tickets from the Cayman Islands is $911 and $903 respectively. For one-way flights, the best month to travel is February with an average price of $254.


Good to know

Low seasonJanuary
Cheapest flight$417
Best time to beat the crowds but there is an average 2% increase in price.
Most popular time to fly with an average 8% increase in price.
Flight from George Town to San Francisco

FAQs - booking San Francisco flights

  • How far is San Francisco Airport from central San Francisco?

    You’ll need to travel 12 miles to reach the San Francisco city center from San Francisco Airport.

  • What is the name of San Francisco’s airport?

    San Francisco is served by San Francisco Airport, also commonly referred to as San Francisco or San Francisco Intl. The airport code is SFO.

  • What is the cheapest day to fly to San Francisco?

    Based on KAYAK data, the cheapest day to fly to San Francisco is Monday where round-trip tickets can be as cheap as $661. On the other hand, the most expensive day to fly is Saturday, where round-trip prices are $870 on average.

  • How does KAYAK find such low prices on flights to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to San Francisco?

    The cheapest time of day to fly to San Francisco is generally in the morning, when round-trip flights cost $678 on average. The most expensive time of day to fly to San Francisco is generally in the evening, which is peak travel time and where the average cost of a ticket is $758.

  • How many direct flights to San Francisco are there each week?

    Each week there are around 3,890 direct flights from within Cayman Islands to San Francisco. The most common day for departures is Sunday, with 15% of flights taking off on this day.

Top tips for finding cheap flights to San Francisco

  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest San Francisco flight deals.

Reviews of the top airline flying from the Cayman Islands to San Francisco

 
See real verified KAYAK customer reviews for airlines flying to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from the Cayman Islands to San Francisco. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
6.5Food
8.0Crew
7.5Boarding
6.9Entertainment
7.2Comfort
Airline reviews

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

10.0 ExcellentBrendan, Jul 2025ORD - SNA
Read more American Airlines reviews

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

Boarding gate in Honolulu was staffed with a great clerk with a soothing voice despite the flight delay of over an hour. Flight attendants in the plane were all grumpy, not pleasant looking bunch. Their sour attitude showed throughout the flight. Inly able to get a select few movies started. Most of the movie links in the “free entertainment” did not work.

I flew Business Class. Rory, one of the Cabin stewards, was attentive, explained the menu, provided appropriate drinks. was

This was a horrible experience. For a first class experience, my chair was held together by 3M tape - and I have a photo. The crew weren’t very attentive, somewhat dismissive and forgot my drink and snack, the chair reclined about 3 inches on a 6-hour cross country flight. I was also not informed that there was no lounge available in Newark airport because of renovations, so all around this was one of the worst experiences and I would actively avoid both American and Alaska Air going forward.

Boarding was very efficient. Everyone got on board and we got on our way very quickly. It was frustrating that the entertainment app was not functioning properly. I was not able to activate some of the movies offered. The crew on this flight appears to be pretty grumpy. They had no smile on their faces. I felt like they were doing us a favor for being there.

Loved the staff, boarding and drink options! Wish the comfort of the seat could have been better nevertheless

Honestly, I haven’t flown American in years, probably due to the pandemic and my being unable to travel for certain periods in the last two years, but it was a good experience to dig out or obtain a new American Airlines account after many years of traveling for business with American in the past.

Long 5 hour and 45 min flight and only one drink service and cookie snack

One bottle of water and a package of cookies for comfort plus. We had to literally beg a flight attendant for an extra bottle of water later in the flight due to feeling dehydrated.

Flight boarded from Gate 39 at OGG, the farthest gate in the terminal. There were no Hawaiian themed amenities for the flight. The first class service was mediocre at best; I received not special welcome or recognition as an executive platinum member of American Advantage program. The flight attendants were more concerned with their cell phones than saying "thank you" to the passengers as we disembarked. Fortunately, the flight arrived at LAX a few minutes early.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Newark
Glen Ellen

Everything you need to know for your flight to San Francisco

Information on the airport you'll fly into in San Francisco

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