$489 Find Cheap Flights from Grand Cayman to San Francisco - Compare and Save

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Cheap Flights from Grand Cayman to San Francisco

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Grand Cayman to San Francisco

Mon, Nov 2 - Fri, Nov 6
Southwest Logo
1:30 pm - 10:40 pmGCM  George Town Owen Roberts Intl-SFO San Francisco
12h 10m2 stops Orlando San Diego
Southwest Logo
6:30 pm - 1:00 pmSFO  San Francisco-GCM George Town Owen Roberts Intl
15h 30m2 stops San Diego Orlando
$562Southwest
Sun, Nov 1 - Fri, Nov 6
Southwest Logo
1:30 pm - 10:40 pmGCM  George Town Owen Roberts Intl-SFO San Francisco
12h 10m2 stops Orlando San Diego
Southwest Logo
6:30 pm - 1:00 pmSFO  San Francisco-GCM George Town Owen Roberts Intl
15h 30m2 stops San Diego Orlando
$638Southwest
Tue, Oct 13 - Thu, Oct 15
WestJet Logo
1:45 pm - 9:55 pmGCM  George Town Owen Roberts Intl-SFO San Francisco
34h 10m2 stops Toronto Pearson Intl Calgary
WestJet Logo
6:00 am - 12:45 pmSFO  San Francisco-GCM George Town Owen Roberts Intl
52h 45m2 stops Calgary Toronto Pearson Intl
$731WestJet
Sun, Nov 1 - Fri, Nov 6
Multiple Airlines Logo
3:35 pm - 12:45 pmGCM  George Town Owen Roberts Intl-SFO San Francisco
24h 10m1 stop Toronto Pearson Intl
Multiple Airlines Logo
12:20 pm - 4:05 pmSFO  San Francisco-GCM George Town Owen Roberts Intl
24h 45m2 stops Denver Intl Tampa
$746Multiple Airlines
Mon, Nov 2 - Fri, Nov 6
Multiple Airlines Logo
3:35 pm - 12:45 pmGCM  George Town Owen Roberts Intl-SFO San Francisco
24h 10m1 stop Toronto Pearson Intl
Multiple Airlines Logo
12:20 pm - 4:05 pmSFO  San Francisco-GCM George Town Owen Roberts Intl
24h 45m2 stops Denver Intl Tampa
$746Multiple Airlines
Tue, Oct 13 - Thu, Oct 15
Multiple Airlines Logo
1:45 pm - 12:20 pmGCM  George Town Owen Roberts Intl-SFO San Francisco
24h 35m1 stop Toronto Pearson Intl
Multiple Airlines Logo
10:14 pm - 9:15 pmSFO  San Francisco-GCM George Town Owen Roberts Intl
21h 01m2 stops Atlanta Hartsfield-Jackson Miami
$762Multiple Airlines
Tue, Oct 13 - Thu, Oct 15
Multiple Airlines Logo
1:45 pm - 6:00 pmGCM  George Town Owen Roberts Intl-SFO San Francisco
30h 15m3 stops Toronto Pearson Intl Edmonton Vancouver Intl
Multiple Airlines Logo
11:59 pm - 9:15 pmSFO  San Francisco-GCM George Town Owen Roberts Intl
19h 16m2 stops Minneapolis St Paul Miami
$779Multiple Airlines
Sat, Oct 31 - Fri, Nov 6
American Airlines Logo
2:10 pm - 11:59 pmGCM  George Town Owen Roberts Intl-SFO San Francisco
11h 49m1 stop Miami
American Airlines Logo
11:47 pm - 11:44 amSFO  San Francisco-GCM George Town Owen Roberts Intl
8h 57m1 stop Miami
$782American Airlines
Tue, Oct 13 - Thu, Oct 15
Multiple Airlines Logo
1:45 pm - 6:00 pmGCM  George Town Owen Roberts Intl-SFO San Francisco
30h 15m3 stops Toronto Pearson Intl Edmonton Vancouver Intl
Multiple Airlines Logo
11:59 pm - 10:30 amSFO  San Francisco-GCM George Town Owen Roberts Intl
32h 31m3 stops Minneapolis St Paul Chicago O'Hare Intl Toronto Pearson Intl
$792Multiple Airlines
Fri, Oct 9 - Wed, Oct 14
American Airlines Logo
12:00 pm - 7:33 pmGCM  George Town Owen Roberts Intl-SFO San Francisco
9h 33m1 stop Miami
American Airlines Logo
10:03 pm - 11:30 amSFO  San Francisco-GCM George Town Owen Roberts Intl
11h 27m1 stop Charlotte Douglas
$806American Airlines
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Cheapest flight

$489
Flight from George Town to San Francisco

FAQs for booking flights from Grand Cayman to San Francisco

  • How does KAYAK find such low prices on flights from Grand Cayman to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Grand Cayman to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Grand Cayman to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Grand Cayman is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Grand Cayman to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Grand Cayman with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Grand Cayman to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Grand Cayman up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Grand Cayman to San Francisco

 
Need help choosing which airline to fly with from Grand Cayman to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11993 reviews
6.4Food
7.2Comfort
6.8Entertainment
7.5Boarding
7.9Crew
Airline reviews

Our experience with American Airlines was extremely disappointing and honestly made an already exhausting international journey much worse. After flying all the way from Melbourne and dealing with significant jet lag, the American Airlines experience at LAX was the last thing we needed. The terminal and boarding area felt very old and uncomfortable, with little to no air conditioning and only old fans running in the area. Boarding was also through outdoor stairs rather than a jet bridge, which felt especially inconvenient after such a long journey. Even though we were traveling First Class, the onboard experience was surprisingly poor. There were no meaningful snack options, no decent coffee available to order, and the aircraft was so small that there was barely enough overhead space for carry-on luggage. The staff experience was also disappointing and lacked the warmth or attentiveness we had experienced on our international flights. To make matters worse, the flight departed late, extending an already very long travel day. Overall, the combination of the outdated terminal, uncomfortable boarding process, limited First Class service, small aircraft, poor staff experience, and delay made this an extremely unpleasant final leg of our journey. It significantly worsened our exhaustion and jet lag rather than making the connection home easier. Unfortunately, this experience was bad enough that I do not plan to travel with American Airlines again in the future.

2.0 MediocreAnonymous, Aug 2026
Read more American Airlines reviews

Our experience with American Airlines was extremely disappointing and honestly made an already exhausting international journey much worse. After flying all the way from Melbourne and dealing with significant jet lag, the American Airlines experience at LAX was the last thing we needed. The terminal and boarding area felt very old and uncomfortable, with little to no air conditioning and only old fans running in the area. Boarding was also through outdoor stairs rather than a jet bridge, which felt especially inconvenient after such a long journey. Even though we were traveling First Class, the onboard experience was surprisingly poor. There were no meaningful snack options, no decent coffee available to order, and the aircraft was so small that there was barely enough overhead space for carry-on luggage. The staff experience was also disappointing and lacked the warmth or attentiveness we had experienced on our international flights. To make matters worse, the flight departed late, extending an already very long travel day. Overall, the combination of the outdated terminal, uncomfortable boarding process, limited First Class service, small aircraft, poor staff experience, and delay made this an extremely unpleasant final leg of our journey. It significantly worsened our exhaustion and jet lag rather than making the connection home easier. Unfortunately, this experience was bad enough that I do not plan to travel with American Airlines again in the future.

Horrible. No AC. No Air inside the plane. We had to deplane twice! It is late almost 5 hrs in total. I almost passed out and about to call 911. I asked the crew to be honest and open the door. The lady next to me was lay down in the floor due to heat and no air inside the plane. I got headaches, can’t wait the replacement flight about midnight Dallas time. I end it up rebook for next day flight and stay overnight using my own pocket in a hotel nearby due to headaches and can’t breath. I still have a headache this morning. Still not decided yes how to file this issue to AA and/or FAA.

I could not ask for more. Great service and experience.

Initial flight had an engine overheat - returned to DFW. Had another plane ready, but crew timed out. Had to wait 5h for boarding. Fully boarded and pilot says plane is not flight worthy. Deplane and go to the other end of the terminal. Wait an hour to board third plane because the crew couldn’t leave the second plane because no wheelchairs were brought to remove passengers. Finally take off and there is no catering (in flight service) even in first class. Very much an AA failure.

The food was good. I almost didn't get a seat on the flight unless I agreed to sit in emergency exit.

The flight attendant was very polite and attentive. The food was good.

I had a comfortable and enjoyable experience. The entertainment options were plentiful, the food was appetizing, the snacks were tasty, and the staff was friendly, professional, and helpful.

Was put into a seat right behind the toilet that had no entertainment possible but did have plenty of leg room over noisy part of plane.

Flight: Started on time. Comfortable flight. Arrived on time. Crew: Very cordial and helpful. Drinks and snack was served with a smile. Overall enjoyed the trip. Regards, Hari Doss Chanchala Doss

Buying ticket from kayak instant booking was a huge mistake, never to be repeated again! The Kayak didn’t book the tickets directly, it handed it off to a third party Underpricer, that booked a code shared American Airlines flight operated by Cathay Pacific!! When managing the booking American Airlines would recognize the itinerary but wouldn’t let me do anything stating, the flight is operated by Cathay Pacific so go to their website. Cathay Pacific would recognize the itinerary, neither by reservation ID or ticket number…asking to reach out to the third party Underpricer….calling Underpricer resulted in no help like seat requests, mileage number or upgrade request, 15hr layover accommodation voucher guidance…so net in net avoid booking through three layers of intermediaries

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