$303 Find Cheap Flights from Grand Cayman to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Francisco departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Grand Cayman to San Francisco

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Grand Cayman to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Grand Cayman to San Francisco

Mon, Oct 20 - Sat, Oct 25
Air Canada Logo
12:50 pm - 10:33 amGCM-SFO
23h 43m1 stop
Air Canada Logo
8:40 am - 11:20 amSFO-GCM
24h 40m1 stop
$612Air Canada
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Mon, Oct 20 - Sat, Oct 25
Air Canada Logo
12:50 pm - 3:28 pmGCM-SFO
28h 38m2 stops
Air Canada Logo
8:40 am - 11:20 amSFO-GCM
24h 40m1 stop
$675Air Canada
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Mon, Oct 20 - Sat, Oct 25
 Logo
7:00 am - 12:02 pmGCM-SFO
31h 02m3 stops
 Logo
8:40 am - 11:20 amSFO-GCM
24h 40m1 stop
Sun, Sep 21 - Tue, Sep 23
American Airlines Logo
12:28 pm - 9:51 pmGCM-SFO
11h 23m1 stop
American Airlines Logo
4:25 pm - 11:10 amSFO-GCM
16h 45m2 stops
$811American Airlines
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Mon, Oct 20 - Fri, Oct 24
 Logo
7:00 am - 11:57 pmGCM-SFO
18h 57m2 stops
 Logo
12:43 am - 12:30 pmSFO-GCM
9h 47m1 stop
Sun, Sep 21 - Tue, Sep 23
American Airlines Logo
12:28 pm - 10:48 pmGCM-SFO
12h 20m1 stop
American Airlines Logo
11:58 pm - 11:10 amSFO-GCM
9h 12m1 stop
$820American Airlines
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Mon, Oct 20 - Sat, Oct 25
 Logo
7:00 am - 12:02 pmGCM-SFO
31h 02m3 stops
 Logo
10:15 am - 11:20 amSFO-GCM
23h 05m2 stops
Mon, Oct 20 - Fri, Oct 24
American Airlines Logo
2:05 pm - 10:59 pmGCM-SFO
10h 54m1 stop
American Airlines Logo
12:50 am - 2:00 pmSFO-GCM
11h 10m1 stop
$837American Airlines
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Good to know

Low seasonJanuary
High seasonSeptember
Cheapest flight$303
Best time to beat the crowds but there is an average 2% increase in price.
Most popular time to fly with an average 8% increase in price.
Flight from George Town to San Francisco

FAQs for booking flights from Grand Cayman to San Francisco

  • How does KAYAK find such low prices on flights from Grand Cayman to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Grand Cayman to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Grand Cayman to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Grand Cayman is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Grand Cayman to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Grand Cayman with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Grand Cayman to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Grand Cayman up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Grand Cayman to San Francisco

 
Need help choosing which airline to fly with from Grand Cayman to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
6.5Food
6.9Entertainment
7.5Boarding
7.2Comfort
8.0Crew
Airline reviews

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

10.0 ExcellentBrendan, Jul 2025ORD - SNA
Read more American Airlines reviews

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

Boarding gate in Honolulu was staffed with a great clerk with a soothing voice despite the flight delay of over an hour. Flight attendants in the plane were all grumpy, not pleasant looking bunch. Their sour attitude showed throughout the flight. Inly able to get a select few movies started. Most of the movie links in the “free entertainment” did not work.

I flew Business Class. Rory, one of the Cabin stewards, was attentive, explained the menu, provided appropriate drinks. was

This was a horrible experience. For a first class experience, my chair was held together by 3M tape - and I have a photo. The crew weren’t very attentive, somewhat dismissive and forgot my drink and snack, the chair reclined about 3 inches on a 6-hour cross country flight. I was also not informed that there was no lounge available in Newark airport because of renovations, so all around this was one of the worst experiences and I would actively avoid both American and Alaska Air going forward.

Boarding was very efficient. Everyone got on board and we got on our way very quickly. It was frustrating that the entertainment app was not functioning properly. I was not able to activate some of the movies offered. The crew on this flight appears to be pretty grumpy. They had no smile on their faces. I felt like they were doing us a favor for being there.

Loved the staff, boarding and drink options! Wish the comfort of the seat could have been better nevertheless

Honestly, I haven’t flown American in years, probably due to the pandemic and my being unable to travel for certain periods in the last two years, but it was a good experience to dig out or obtain a new American Airlines account after many years of traveling for business with American in the past.

Long 5 hour and 45 min flight and only one drink service and cookie snack

One bottle of water and a package of cookies for comfort plus. We had to literally beg a flight attendant for an extra bottle of water later in the flight due to feeling dehydrated.

Flight boarded from Gate 39 at OGG, the farthest gate in the terminal. There were no Hawaiian themed amenities for the flight. The first class service was mediocre at best; I received not special welcome or recognition as an executive platinum member of American Advantage program. The flight attendants were more concerned with their cell phones than saying "thank you" to the passengers as we disembarked. Fortunately, the flight arrived at LAX a few minutes early.

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