$272 Find Cheap Flights from Grand Cayman to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Francisco departing on 6/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$515
Southwest
Wed 4/8Sun 4/12
GCM - SFO • 2 stops
Cheapest one-way
$305
Typical prices: $539-$568
JetBlue
Thu 6/11
GCM - SFO • 1 stop
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Flight Deals
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Flight Deals

Cheap Flights from Grand Cayman to San Francisco

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Grand Cayman to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Grand Cayman to San Francisco

Wed, Apr 8 - Sun, Apr 12
Southwest Logo
1:05 pm - 11:35 pm
GCM
-
SFO
12h 30m
2 stops
Southwest Logo
9:15 pm - 12:10 pm
SFO
-
GCM
12h 55m
2 stops
$515Southwest
Thu, Jun 11 - Mon, Aug 31
JetBlue Logo
2:55 pm - 11:55 pm
GCM
-
SFO
11h 00m
1 stop
JetBlue Logo
9:00 pm - 1:55 pm
SFO
-
GCM
14h 55m
1 stop
$536JetBlue
Wed, Mar 11 - Wed, Mar 18
Multiple Airlines Logo
8:00 am - 8:36 pm
GCM
-
SFO
14h 36m
1 stop
Multiple Airlines Logo
11:06 am - 1:01 pm
SFO
-
GCM
23h 55m
1 stop
$575Multiple Airlines
Fri, Apr 17 - Sun, Apr 19
Southwest Logo
1:05 pm - 12:20 am
GCM
-
SFO
13h 15m
2 stops
Southwest Logo
4:40 pm - 12:10 pm
SFO
-
GCM
17h 30m
2 stops
$578Southwest
Wed, Mar 11 - Wed, Mar 18
Multiple Airlines Logo
8:00 am - 8:36 pm
GCM
-
SFO
14h 36m
1 stop
Multiple Airlines Logo
10:38 pm - 9:15 pm
SFO
-
GCM
20h 37m
2 stops
$596Multiple Airlines
Fri, Apr 17 - Sun, Apr 19
Air Canada Logo
12:30 pm - 10:45 am
GCM
-
SFO
24h 15m
1 stop
Air Canada Logo
1:20 pm - 11:10 am
SFO
-
GCM
19h 50m
2 stops
$638Air Canada
Mon, Mar 30 - Sat, Apr 11
Air Canada Logo
12:30 pm - 9:23 am
GCM
-
SFO
22h 53m
1 stop
Air Canada Logo
1:20 pm - 11:10 am
SFO
-
GCM
19h 50m
2 stops
$702Air Canada
Wed, Apr 8 - Sun, Apr 12
American Airlines Logo
12:00 pm - 8:49 pm
GCM
-
SFO
10h 49m
1 stop
American Airlines Logo
10:28 pm - 11:32 am
SFO
-
GCM
11h 04m
1 stop
$722American Airlines
Mon, Mar 30 - Fri, Apr 10
American Airlines Logo
11:40 am - 11:10 pm
GCM
-
SFO
13h 30m
1 stop
American Airlines Logo
12:30 am - 3:03 pm
SFO
-
GCM
12h 33m
1 stop
$731American Airlines
Wed, Mar 11 - Tue, Mar 17
American Airlines Logo
7:45 am - 7:47 pm
GCM
-
SFO
14h 02m
2 stops
American Airlines Logo
12:25 am - 1:35 pm
SFO
-
GCM
11h 10m
2 stops
$736American Airlines
Useful Info

Good to know

Cheapest flight$305
Flight from George Town to San Francisco

FAQs for booking flights from Grand Cayman to San Francisco

  • How does KAYAK find such low prices on flights from Grand Cayman to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Grand Cayman to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Grand Cayman to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Grand Cayman is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Grand Cayman to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Grand Cayman with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Grand Cayman to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Grand Cayman up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Grand Cayman to San Francisco

 
Need help choosing which airline to fly with from Grand Cayman to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11197 reviews
7.2Comfort
7.5Boarding
6.9Entertainment
8.0Crew
6.4Food
Airline reviews

We were upgraded to Business Class. So comfortable with great service and food options

10.0 ExcellentRobert, Jan 2026
AKL - LAX
Read more American Airlines reviews

We were upgraded to Business Class. So comfortable with great service and food options

The flight was completely full. Crew was not happy. Everyone was rude and brusque. Travelling with an arm in a cast and seating in the first row of economy cabin (in front of the separation) I needed help retrieving my tray for the meal. A staff member literally threw the tray on my lap, without helping to take out the tray. Boarding was messy, with 300 people waiting in an encloses space with low ceiling. I will try to avoid AA next time I have a long flight.

The comfort of Business Class made this trip far more comfortable. I was indeed surprised when I asked one of the flight attendant to help me set up my "bed", she responded that "We don't make beds in Business Class any longer...only First Class" I believe her name was Giselle, but I'm not certain. She did instruct me how to adjust the seat, place the hooded cover and I clearly understood how to place the blanket and the cover. Additionally, the meal I was served (a beef dish) was almost inedible. The beef was tough and odd tasting. I didn't mention it as I was hoping to quickly settle down and try to get some sleep.

Amazing I love American. I’ll never fly anyone else if I can help it.

Everything about the flight was lovely. My only suggestion would be to offer a few more options of tv series from Apple TV or HBO.

After the door had been closed, the cockpit makes an announcement that catering is running late and it is not the airline's fault. It is their fault in the sense that we had to sit for 2 hours or more when we could have stayed in the terminal. Poor communications between catering and airline. This caused a young man to lose his temper and he went storming out hitting objects. He had complained to the gate agent that he had already waited at the gate 7 hours and when can the airplane leave? Airilnes do a poor job of explaining delays, maintenance issues, etc. whereas being truthful may gain more sympathy or understanding.

We were told the flight was delayed 5 times, then it was moved to the next day.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

Loved the crew . Absolutely no complaints. Except for luggage lost

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

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