$250 Find Cheap Flights from Grand Cayman to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Francisco departing on 2/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$385
JetBlue
Tue 1/6Thu 1/15
GCM - SFO • 1 stop
Cheapest one-way
$245
Typical prices: $465-$650
JetBlue
Thu 2/12
GCM - SFO • 1 stop
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Flight Deals
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Flight Deals

Cheap Flights from Grand Cayman to San Francisco

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Grand Cayman to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Grand Cayman to San Francisco

Tue, Jan 6 - Thu, Jan 15
JetBlue Logo
3:30 pm - 11:29 pmGCM-SFO
10h 59m1 stop
JetBlue Logo
10:37 pm - 2:32 pmSFO-GCM
12h 55m1 stop
$385JetBlue
Find Deal
Tue, Jan 6 - Sat, Jan 17
JetBlue Logo
3:30 pm - 11:29 pmGCM-SFO
10h 59m1 stop
JetBlue Logo
10:37 pm - 2:32 pmSFO-GCM
12h 55m1 stop
$444JetBlue
Find Deal
Tue, Jan 27 - Wed, Feb 4
Multiple Airlines Logo
5:25 pm - 12:38 pmGCM-SFO
22h 13m1 stop
Multiple Airlines Logo
2:08 pm - 1:53 pmSFO-GCM
20h 45m2 stops
$473Multiple Airlines
Find Deal
Thu, Jan 29 - Wed, Feb 4
Multiple Airlines Logo
5:25 pm - 12:38 pmGCM-SFO
22h 13m1 stop
Multiple Airlines Logo
2:08 pm - 1:53 pmSFO-GCM
20h 45m2 stops
$474Multiple Airlines
Find Deal
Tue, Jan 27 - Sat, Feb 7
JetBlue Logo
3:30 pm - 11:29 pmGCM-SFO
10h 59m1 stop
JetBlue Logo
10:40 pm - 2:35 pmSFO-GCM
12h 55m1 stop
$476JetBlue
Find Deal
Tue, Jan 27 - Sat, Feb 7
JetBlue Logo
3:30 pm - 11:29 pmGCM-SFO
10h 59m1 stop
JetBlue Logo
10:40 pm - 2:35 pmSFO-GCM
12h 55m1 stop
$477JetBlue
Find Deal
Tue, Jan 27 - Sat, Feb 7
Multiple Airlines Logo
5:25 pm - 12:38 pmGCM-SFO
22h 13m1 stop
Multiple Airlines Logo
4:46 pm - 1:53 pmSFO-GCM
18h 07m2 stops
$478Multiple Airlines
Find Deal
Thu, Jan 29 - Sat, Feb 7
Multiple Airlines Logo
5:25 pm - 12:38 pmGCM-SFO
22h 13m1 stop
Multiple Airlines Logo
4:46 pm - 1:53 pmSFO-GCM
18h 07m2 stops
$480Multiple Airlines
Find Deal
Sun, Jan 11 - Tue, Jan 13
Multiple Airlines Logo
2:50 pm - 12:38 pmGCM-SFO
24h 48m1 stop
Multiple Airlines Logo
7:00 am - 4:05 pmSFO-GCM
30h 05m2 stops
$483Multiple Airlines
Find Deal
Sun, Jan 11 - Tue, Jan 13
Multiple Airlines Logo
2:50 pm - 12:38 pmGCM-SFO
24h 48m1 stop
Multiple Airlines Logo
11:20 pm - 1:53 pmSFO-GCM
35h 33m2 stops
$484Multiple Airlines
Find Deal
Useful Info

Good to know

Low seasonFebruary
Cheapest flight$245
Best time to beat the crowds with an average 65% drop in price.
Most popular time to fly with an average 105% increase in price.
Flight from George Town to San Francisco

FAQs for booking flights from Grand Cayman to San Francisco

  • How does KAYAK find such low prices on flights from Grand Cayman to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Grand Cayman to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Grand Cayman to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Grand Cayman is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Grand Cayman to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Grand Cayman with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Grand Cayman to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Grand Cayman up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Grand Cayman to San Francisco

 
Need help choosing which airline to fly with from Grand Cayman to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11042 reviews
6.9Entertainment
7.2Comfort
6.4Food
8.0Crew
7.5Boarding
Airline reviews

We were told the flight was delayed 5 times, then it was moved to the next day.

2.0 MediocreAnonymous, Nov 2025DCA - LAX
Read more American Airlines reviews

We were told the flight was delayed 5 times, then it was moved to the next day.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

Loved the crew . Absolutely no complaints. Except for luggage lost

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

We are too tired and frustrated to comment politely at this point

The business class seats are dated and uncomfortable. The space is bare minimum and there is absolutely no privacy. For $4K, this is not what I expect.

The flight crew was rude. We were in first class and no one even offered water until an hour after we were in the air. Horrible experience

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Did not get the seat I selected and paid for.

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Everything you need to know for your flight to San Francisco

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