$528 Find Cheap Flights from Grand Cayman to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Francisco departing on 7/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Grand Cayman to San Francisco

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Grand Cayman to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Grand Cayman to San Francisco

Sat, Aug 22 - Wed, Aug 26
Multiple Airlines Logo
4:00 pm - 8:40 pm
GCM
-
SFO
30h 40m
1 stop
Multiple Airlines Logo
10:35 pm - 9:15 pm
SFO
-
GCM
20h 40m
2 stops
$703Multiple Airlines
Thu, Aug 13 - Sun, Aug 23
Delta Logo
1:04 pm - 11:58 pm
GCM
-
SFO
12h 54m
1 stop
Delta Logo
11:15 pm - 11:39 am
SFO
-
GCM
10h 24m
1 stop
$772Delta
Fri, Oct 9 - Sun, Oct 18
Multiple Airlines Logo
7:00 am - 4:57 pm
GCM
-
SFO
35h 57m
2 stops
Multiple Airlines Logo
10:20 pm - 2:45 pm
SFO
-
GCM
14h 25m
1 stop
$780Multiple Airlines
Sat, Aug 8 - Fri, Aug 14
United Airlines Logo
4:45 pm - 7:22 am
GCM
-
SFO
16h 37m
1 stop
United Airlines Logo
12:45 am - 12:25 pm
SFO
-
GCM
9h 40m
1 stop
$781United Airlines
Sat, Aug 8 - Sat, Aug 15
American Airlines Logo
4:00 pm - 8:50 am
GCM
-
SFO
18h 50m
2 stops
American Airlines Logo
3:46 pm - 11:00 am
SFO
-
GCM
17h 14m
2 stops
$786American Airlines
Sat, Aug 22 - Wed, Aug 26
American Airlines Logo
12:30 pm - 11:10 pm
GCM
-
SFO
12h 40m
2 stops
American Airlines Logo
4:31 pm - 11:00 am
SFO
-
GCM
16h 29m
2 stops
$791American Airlines
Sun, Jul 26 - Fri, Jul 31
Delta Logo
12:56 pm - 10:49 pm
GCM
-
SFO
11h 53m
1 stop
Delta Logo
11:59 pm - 11:31 am
SFO
-
GCM
9h 32m
1 stop
$942Delta
Sat, Aug 22 - Wed, Aug 26
Multiple Airlines Logo
1:45 pm - 12:00 pm
GCM
-
SFO
24h 15m
2 stops
Multiple Airlines Logo
12:15 pm - 11:25 am
SFO
-
GCM
21h 10m
3 stops
$1,076Multiple Airlines
Sun, Jul 26 - Fri, Jul 31
American Airlines Logo
12:02 pm - 12:43 am
GCM
-
SFO
14h 41m
2 stops
American Airlines Logo
11:20 pm - 2:15 pm
SFO
-
GCM
12h 55m
1 stop
$1,104American Airlines
Fri, Oct 9 - Sun, Oct 18
Multiple Airlines Logo
7:00 am - 11:17 am
GCM
-
SFO
30h 17m
3 stops
Multiple Airlines Logo
4:35 pm - 11:30 am
SFO
-
GCM
16h 55m
2 stops
$1,121Multiple Airlines
Useful Info

Good to know

Cheapest flight$528
Flight from George Town to San Francisco

FAQs for booking flights from Grand Cayman to San Francisco

  • How does KAYAK find such low prices on flights from Grand Cayman to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Grand Cayman to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Grand Cayman to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Grand Cayman is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Grand Cayman to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Grand Cayman with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Grand Cayman to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Grand Cayman up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Grand Cayman to San Francisco

 
Need help choosing which airline to fly with from Grand Cayman to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11774 reviews
6.8Entertainment
7.5Boarding
7.9Crew
7.2Comfort
6.4Food
Airline reviews

Was put into a seat right behind the toilet that had no entertainment possible but did have plenty of leg room over noisy part of plane.

6.0 GoodElizabeth, May 2026
DFW - SFO
Read more American Airlines reviews

Was put into a seat right behind the toilet that had no entertainment possible but did have plenty of leg room over noisy part of plane.

Flight: Started on time. Comfortable flight. Arrived on time. Crew: Very cordial and helpful. Drinks and snack was served with a smile. Overall enjoyed the trip. Regards, Hari Doss Chanchala Doss

Buying ticket from kayak instant booking was a huge mistake, never to be repeated again! The Kayak didn’t book the tickets directly, it handed it off to a third party Underpricer, that booked a code shared American Airlines flight operated by Cathay Pacific!! When managing the booking American Airlines would recognize the itinerary but wouldn’t let me do anything stating, the flight is operated by Cathay Pacific so go to their website. Cathay Pacific would recognize the itinerary, neither by reservation ID or ticket number…asking to reach out to the third party Underpricer….calling Underpricer resulted in no help like seat requests, mileage number or upgrade request, 15hr layover accommodation voucher guidance…so net in net avoid booking through three layers of intermediaries

A first class seat should fit a fat person, and this doesn't. The trays in the armrest are less functional than an ordinary tray in the back of the seat.

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

I flew Business Class. Rory, one of the Cabin stewards, was attentive, explained the menu, provided appropriate drinks. was

This was a horrible experience. For a first class experience, my chair was held together by 3M tape - and I have a photo. The crew weren’t very attentive, somewhat dismissive and forgot my drink and snack, the chair reclined about 3 inches on a 6-hour cross country flight. I was also not informed that there was no lounge available in Newark airport because of renovations, so all around this was one of the worst experiences and I would actively avoid both American and Alaska Air going forward.

Long 5 hour and 45 min flight and only one drink service and cookie snack

Extraordinary service in business class, and very good breakfast and snacks. A really lovely flight.

This flight didn’t happen because AA agents didn’t let us board the flight

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