$250 Find Cheap Flights from Grand Cayman to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Francisco departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$381
JetBlue
Sat 1/17Sat 1/24
GCM - SFO • 1 stop
Cheapest one-way
$250
Typical prices: $487-$975
JetBlue
Tue 1/13
GCM - SFO • 1 stop
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Flight Deals
Useful Info
Flight Deals

Cheap Flights from Grand Cayman to San Francisco

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Grand Cayman to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Grand Cayman to San Francisco

Sat, Jan 17 - Sat, Jan 24
JetBlue Logo
2:55 pm - 11:29 pm
GCM
-
SFO
11h 34m1 stop
JetBlue Logo
10:37 pm - 2:32 pm
SFO
-
GCM
12h 55m1 stop
$381JetBlue
Fri, Jan 30 - Fri, Feb 6
JetBlue Logo
3:40 pm - 2:07 pm
GCM
-
SFO
25h 27m1 stop
JetBlue Logo
8:00 am - 1:55 pm
SFO
-
GCM
26h 55m1 stop
$471JetBlue
Sun, Feb 1 - Sun, Feb 8
JetBlue Logo
3:40 pm - 10:49 pm
GCM
-
SFO
34h 09m1 stop
JetBlue Logo
8:30 pm - 2:35 pm
SFO
-
GCM
15h 05m2 stops
$544JetBlue
Sun, Feb 1 - Sun, Feb 8
Multiple Airlines Logo
2:49 pm - 12:54 pm
GCM
-
SFO
25h 05m2 stops
Multiple Airlines Logo
1:45 pm - 1:44 pm
SFO
-
GCM
20h 59m1 stop
$556Multiple Airlines
Sun, Feb 1 - Sun, Feb 8
Multiple Airlines Logo
2:50 pm - 12:45 pm
GCM
-
SFO
24h 55m1 stop
Multiple Airlines Logo
1:45 pm - 1:44 pm
SFO
-
GCM
20h 59m1 stop
$584Multiple Airlines
Sun, Feb 1 - Sun, Feb 8
JetBlue Logo
3:40 pm - 10:59 pm
GCM
-
SFO
34h 19m2 stops
JetBlue Logo
8:30 pm - 2:35 pm
SFO
-
GCM
15h 05m2 stops
$587JetBlue
Sun, Feb 1 - Sun, Feb 8
Multiple Airlines Logo
2:50 pm - 12:45 pm
GCM
-
SFO
24h 55m1 stop
Multiple Airlines Logo
1:45 pm - 1:44 pm
SFO
-
GCM
20h 59m1 stop
$590Multiple Airlines
Sat, Jan 17 - Sat, Jan 24
Multiple Airlines Logo
4:00 pm - 11:07 pm
GCM
-
SFO
10h 07m1 stop
Multiple Airlines Logo
4:46 pm - 1:53 pm
SFO
-
GCM
18h 07m2 stops
$598Multiple Airlines
Thu, Jan 22 - Sat, Jan 24
Air Canada Logo
1:30 pm - 1:30 pm
GCM
-
SFO
27h 00m1 stop
Air Canada Logo
8:30 am - 12:25 pm
SFO
-
GCM
24h 55m1 stop
$603Air Canada
Thu, Jan 22 - Sat, Jan 24
Air Canada Logo
1:30 pm - 3:35 pm
GCM
-
SFO
29h 05m2 stops
Air Canada Logo
8:30 am - 12:25 pm
SFO
-
GCM
24h 55m1 stop
$622Air Canada
Useful Info

Good to know

Low seasonFebruary
Cheapest flight$250
Best time to beat the crowds with an average 64% drop in price.
Most popular time to fly with an average 110% increase in price.
Flight from George Town to San Francisco

FAQs for booking flights from Grand Cayman to San Francisco

  • How does KAYAK find such low prices on flights from Grand Cayman to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Grand Cayman to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Grand Cayman to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Grand Cayman is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Grand Cayman to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Grand Cayman with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Grand Cayman to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Grand Cayman up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Grand Cayman to San Francisco

 
Need help choosing which airline to fly with from Grand Cayman to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11057 reviews
8.0Crew
7.2Comfort
7.5Boarding
6.5Food
6.9Entertainment
Airline reviews

We were told the flight was delayed 5 times, then it was moved to the next day.

2.0 MediocreAnonymous, Nov 2025
DCA - LAX
Read more American Airlines reviews

We were told the flight was delayed 5 times, then it was moved to the next day.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

Loved the crew . Absolutely no complaints. Except for luggage lost

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

We are too tired and frustrated to comment politely at this point

The business class seats are dated and uncomfortable. The space is bare minimum and there is absolutely no privacy. For $4K, this is not what I expect.

The flight crew was rude. We were in first class and no one even offered water until an hour after we were in the air. Horrible experience

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Did not get the seat I selected and paid for.

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