CHS - SDQ

$169 Find Cheap Flights from Charleston to Santo Domingo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to Santo Domingo departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santo Domingo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Charleston to Santo Domingo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Charleston to Santo Domingo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$372
Overall average: $600
JetBlue, Spirit Airlines
Wed 3/25Thu 4/2
CHS - SDQ • 1 stop
Cheapest one-way
$169
Typical prices: $326-$340
Multiple Airlines
Tue 5/5
CHS - SDQ • 1 stop
Top airlines
Cheapest • from $385 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Charleston and Santo Domingo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $426 (round-trip)
Shortest trip • 6h 00m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 26% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Charleston to Santo Domingo (CHS-SDQ)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to Santo Domingo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to Santo Domingo

Wed, Mar 25 - Thu, Apr 2
Multiple Airlines Logo
12:05 pm - 7:46 pm
CHS
-
SDQ
7h 41m
1 stop
Multiple Airlines Logo
2:20 pm - 10:13 pm
SDQ
-
CHS
7h 53m
1 stop
$372Multiple Airlines
Wed, Apr 22 - Sat, Apr 25
Delta Logo
6:00 am - 6:34 pm
CHS
-
SDQ
12h 34m
1 stop
Delta Logo
6:05 am - 5:06 pm
SDQ
-
CHS
11h 01m
1 stop
$385Delta
Wed, Apr 22 - Sat, Apr 25
JetBlue Logo
11:18 am - 6:20 pm
CHS
-
SDQ
7h 02m
1 stop
JetBlue Logo
5:40 am - 5:00 pm
SDQ
-
CHS
11h 20m
1 stop
$388JetBlue
Wed, Apr 22 - Sat, Apr 25
Delta Logo
5:20 am - 6:34 pm
CHS
-
SDQ
13h 14m
2 stops
Delta Logo
6:05 am - 5:06 pm
SDQ
-
CHS
11h 01m
1 stop
$389Delta
Wed, Apr 22 - Sat, Apr 25
Delta Logo
7:25 am - 1:12 pm
CHS
-
SDQ
5h 47m
1 stop
Delta Logo
6:05 am - 5:06 pm
SDQ
-
CHS
11h 01m
1 stop
$393Delta
Wed, Apr 22 - Sat, Apr 25
Delta Logo
5:20 am - 6:34 pm
CHS
-
SDQ
13h 14m
2 stops
Delta Logo
6:05 am - 5:06 pm
SDQ
-
CHS
11h 01m
1 stop
$397Delta
Wed, Apr 22 - Mon, Apr 27
American Airlines Logo
8:09 pm - 2:59 pm
CHS
-
SDQ
18h 50m
1 stop
American Airlines Logo
4:00 pm - 10:34 am
SDQ
-
CHS
18h 34m
1 stop
$400American Airlines
Fri, Apr 24 - Mon, Apr 27
American Airlines Logo
6:00 am - 4:55 pm
CHS
-
SDQ
10h 55m
1 stop
American Airlines Logo
4:00 pm - 10:34 am
SDQ
-
CHS
18h 34m
1 stop
$401American Airlines
Wed, Apr 1 - Sat, Apr 4
Spirit Airlines Logo
8:07 am - 1:38 am
CHS
-
SDQ
17h 31m
1 stop
Spirit Airlines Logo
2:52 am - 10:13 pm
SDQ
-
CHS
19h 21m
1 stop
$402Spirit Airlines
Wed, Apr 22 - Mon, Apr 27
American Airlines Logo
8:21 pm - 1:18 pm
CHS
-
SDQ
16h 57m
2 stops
American Airlines Logo
4:00 pm - 10:34 am
SDQ
-
CHS
18h 34m
1 stop
$405American Airlines
Booking Insights

KAYAK's insights & trends for Charleston to Santo Domingo flights

Get data-powered insights and trends into flights from Charleston to Santo Domingo to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Charleston to Santo Domingo?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Charleston to Santo Domingo, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Charleston to Santo Domingo is November, where tickets cost $375 (return) on average. On the other hand, the most expensive months are February and December, where the average cost of round-trip tickets is $635 and $615 respectively.

Good to know

Low seasonJune
Cheapest flight$169
Most popular time to fly with an average 6% increase in price.
Flight from Charleston to Santo Domingo

When to book flights from Charleston to Santo Domingo

Are your dates flexible? Find out the best times to travel from Charleston to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Charleston to Santo Domingo

  • What is the cheapest flight from Charleston to Santo Domingo?

    In the last 3 days, the lowest price for a flight from Charleston to Santo Domingo was $169 for a one-way ticket and $385 for a round-trip.

  • Do I need a passport to fly between Charleston and Santo Domingo?

    Yes, you’ll need a passport to travel to Santo Domingo from Charleston.

  • Which airports will I be using when flying from Charleston to Santo Domingo?

    When flying out of Charleston you will be using Charleston. You will be landing at Santo Domingo, also known as Santo Domingo Las Americas.

  • Which aircraft models fly most regularly from Charleston to Santo Domingo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Charleston to Santo Domingo?

    SkyTeam, and oneworld are the airline alliances operating flights between Charleston and Santo Domingo, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Charleston to Santo Domingo, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Charleston to Santo Domingo are Delta and American Airlines. With an average price for the route of $597 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $475 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Charleston to Santo Domingo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to Santo Domingo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to Santo Domingo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santo Domingo from Charleston is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to Santo Domingo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santo Domingo with an airline and back to Charleston with another airline. Booking your flights between Charleston and SDQ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to Santo Domingo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santo Domingo from Charleston up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Charleston to Santo Domingo

 
See real verified KAYAK customer reviews for airlines flying from Charleston to Santo Domingo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Charleston to Santo Domingo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8313 reviews
8.1Boarding
8.5Crew
7.2Food
7.8Entertainment
7.9Comfort
Airline reviews

the crew cancel the morning service due to the weather. Then the flight got deverted to Nashville . we were on the ground for over two hours the only gave us water once... no food or any snacks.... the crew should have handled better and offered something to passengers.

2.0 MediocreAnonymous, Mar 2026
HNL - ATL
Read more Delta reviews

the crew cancel the morning service due to the weather. Then the flight got deverted to Nashville . we were on the ground for over two hours the only gave us water once... no food or any snacks.... the crew should have handled better and offered something to passengers.

My recent experience was excellent on Delta! I flew with Delta Comfort and I was really comfortable in my seat. I enjoyed the in-flight service. The flight attendants were so friendly and hospitable. I love the snack on the flight as well. This was my first time flying on Delta and I will definitely consider flying with them again.

My flight was cencaled due with the bad weather on Sunday the crew was poorly mistaken my luggage supposed depart with my flight instead I didn’t have my luggage for almost 3 days the website is poorly respond to my complain until I have someone to do it my connection smooth their not even respon or email me even the have my luggage

Delta needs to step its game up get a more reliable internet service. Internet service was non-existent for this flight.

Mechanical Delay of over an hour with multiple gate changes. Entertainment system down for rejuvenation.

This was a Latam operated flight. Seats seemed a bit narrow in business class. Older aircraft.

I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.

NEVER MADE THE FLIGHT BECAUSE DELTA SAID THEY CAN NOT

THEY FAILED ME AND I NEVER GOT ON THE FLIGHT BECAUSE IT WAS SO DELAYED! I ENDED UP HAVING TO PAY OUT OF POCKET FOR A HOTEL AND STAY IN NASHVILLE TO CATCH A FLIGHT FOR THE FOLLOWING DAY. DELTA IS POOR CUSTOMER SERVICE>

8 hours late and the plane smelled like urine, that smell in the morning when your child wet the bed in the night.

Absolutely terrible. Would never fly American again. 2 deplaned incidents and delayed by close to 24 hours. $12 meal voucher for first class passengers was an insult to the injury. Pathetic.

Terrible planning. And even worse gate agents. Absolutely rude behavior.

Half of the TSA checkpoints at PHL are closed. Also, there is no standby for first class passengers. You can only standby for coach. Very dated policy and inconsistent with peers.

Flight was scheduled at 11:26am but they keep Delaying until midnight. They waited at airport restless.

Rough flight No beverage service due to turbulence Bottom Seat cushion was non existent

Great experience. Good dinner and service. FA's were very nice and attentive.

It was great. Smooth flight, comfortable, left on time and landed on time.

Perhaps this is an airport issue, but being in a takeoff queue for over an hour in the taxiing lane is unacceptable. We will definitely be seeking alternative avenues for air travel in the future.

We hoarded. Then we deplaned. Then we waited for 10 hours in the MSP airport due to a wheel misfunction. We understand safety but communication between crew and airport staff was horrible. When we did finally board, we were rushed on and because we were waiting for a “fresh” pilot and crew, we sat in a roasting plane with no A/C for an hour. My question is why was this flight not cancelled right away when they knew this would be a huge issue OR, why did AA not get a substitute plane, considering this was already a full flight? To me, this appears to be a complete breakdown in leadership and utter systems failure. The compensation for completely disrupting travel plans for hundreds, which we paid dearly for, was measly. While we appreciated the lodging for the night, $12 in meal vouchers isn’t going to sustain anyone for over 12 hours. “We apologize; our hands are tied” is no longer an acceptable explanation. We are so completely turned off by this experience and will definitely seek alternative avenues when we need to fly.

Mostly good. The WiFi wasn’t working so that was not great.

Everything you need to know for your flight from Charleston to Santo Domingo

Information on your arrival and departure airports