CRW - DSM

$341 Find Cheap Flights from Charleston to Des Moines

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to Des Moines departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Charleston to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Charleston to Des Moines, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$341
American Airlines
Sun 4/26Sat 5/2
CRW - DSM • 2 stops
Top airlines
American Airlines
Cheapest • from $341 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Charleston and Des Moines. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Atlanta (ATL)
Cheapest • Avg $353 (round-trip)
Charlotte (CLT)
Shortest trip • 5h 02m (one-way)
Insights
Insights
Insights
Insights
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We hope you love your trip to Des Moines!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Charleston to Des Moines (CRW-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to Des Moines

Sun, Apr 26 - Sat, May 2
American Airlines Logo
5:00 am - 4:31 pm
CRW
-
DSM
12h 31m
2 stops
American Airlines Logo
1:50 pm - 10:20 pm
DSM
-
CRW
7h 30m
1 stop
$341American Airlines
Sun, Apr 26 - Sat, May 2
United Airlines Logo
7:24 pm - 11:02 pm
CRW
-
DSM
4h 38m
1 stop
United Airlines Logo
10:02 am - 5:09 pm
DSM
-
CRW
6h 07m
1 stop
$363United Airlines
Sun, Apr 26 - Sat, May 2
United Airlines Logo
7:24 pm - 11:02 pm
CRW
-
DSM
4h 38m
1 stop
United Airlines Logo
5:30 am - 2:46 pm
DSM
-
CRW
8h 16m
2 stops
$369United Airlines
Sun, Apr 26 - Sat, May 2
American Airlines Logo
5:00 am - 4:31 pm
CRW
-
DSM
12h 31m
2 stops
American Airlines Logo
11:09 am - 11:59 pm
DSM
-
CRW
11h 50m
2 stops
$379American Airlines
Sun, Apr 26 - Sat, May 2
American Airlines Logo
6:00 am - 12:55 pm
CRW
-
DSM
7h 55m
1 stop
American Airlines Logo
1:50 pm - 10:20 pm
DSM
-
CRW
7h 30m
1 stop
$396American Airlines
Sun, Apr 26 - Sat, May 2
American Airlines Logo
5:00 am - 4:31 pm
CRW
-
DSM
12h 31m
2 stops
American Airlines Logo
1:50 pm - 10:20 pm
DSM
-
CRW
7h 30m
1 stop
$397American Airlines
Sun, Apr 26 - Sat, May 2
American Airlines Logo
5:00 am - 4:31 pm
CRW
-
DSM
12h 31m
2 stops
American Airlines Logo
8:56 am - 10:20 pm
DSM
-
CRW
12h 24m
2 stops
$439American Airlines
Sun, Apr 26 - Sat, May 2
American Airlines Logo
5:00 am - 4:31 pm
CRW
-
DSM
12h 31m
2 stops
American Airlines Logo
8:56 am - 10:20 pm
DSM
-
CRW
12h 24m
2 stops
$525American Airlines
Sun, Apr 26 - Sat, May 2
American Airlines Logo
5:00 am - 4:31 pm
CRW
-
DSM
12h 31m
2 stops
American Airlines Logo
8:03 pm - 10:34 am
DSM
-
CRW
13h 31m
2 stops
$529American Airlines
Tue, Mar 10 - Sat, Mar 14
United Airlines Logo
6:45 am - 10:30 am
CRW
-
DSM
4h 45m
1 stop
United Airlines Logo
6:49 pm - 11:54 pm
DSM
-
CRW
4h 05m
1 stop
$879United Airlines
Booking Insights

KAYAK's insights & trends for Charleston to Des Moines flights

Get data-powered insights and trends into flights from Charleston to Des Moines to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Charleston to Des Moines?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Charleston to Des Moines were found on American Airlines ($341) and United Airlines ($363).

Find deals

Good to know

Cheapest flight$341
Flight from Charleston to Des Moines

When to book flights from Charleston to Des Moines

Are your dates flexible? Find out the best times to travel from Charleston to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Charleston to Des Moines

  • What is the cheapest flight from Charleston to Des Moines?

    In the last 3 days, the lowest price for a flight from Charleston to Des Moines was $341 for a round-trip ticket.

  • Do I need a passport to fly between Charleston and Des Moines?

    No, a passport isn't needed to fly from Charleston to Des Moines. However, local authorities might ask for an official ID.

  • Which airports will I be using when flying from Charleston to Des Moines?

    Charleston and Des Moines are both served by 1 main airport. You will leave Charleston from Charleston Yeager and will be arriving at Des Moines.

  • Which aircraft models fly most regularly from Charleston to Des Moines?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Charleston to Des Moines?

    Star Alliance is the only airline alliance operating flights between Charleston and Des Moines.

  • How does KAYAK find such low prices on flights from Charleston to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from Charleston is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to Charleston with another airline. Booking your flights between Charleston and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from Charleston up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Charleston to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from Charleston to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Charleston to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9342 reviews
6.6Food
8.1Crew
7.3Comfort
7.7Boarding
7.1Entertainment
Airline reviews

Flight left on time and we arrived 25 minutes early! There was a gate available when we arrived so early on a busy Sunday afternoon! Flight attendants came around twice with the drinks cart.

10.0 ExcellentAnonymous, Feb 2026
DEN - RSW
Read more United Airlines reviews

Flight left on time and we arrived 25 minutes early! There was a gate available when we arrived so early on a busy Sunday afternoon! Flight attendants came around twice with the drinks cart.

Wonderful. Quick boarding. Early departure and we arrived 30 minutes early at our destination. Unfortunately, when you arrive early, there is still a departing aircraft at our gate. We had to park for 30 minutes until the gate was clear. So our early arrival was not really early at the gate. Otherwise it was a quick and smooth flight. Appreciated the efficiency.

Everything was great except for the boarding process. Everyone is lining up all at the same time and it’s hard to tell between the groups as they are way too large.

Women boarding passengers at the gate was absolutely rude and disrespectful of passengers. The flight attendant was absolutely delightful! Smiling and connected with the passengers. So happy. The seats are cramped and uncomfortable but I guess that’s just the way it is Communication regarding flight was excellent

Overall we had a good experience during our flight from San Francisco to Houston.

Airport terminal was outdated, flight was on a small jet with no wifi

We were delayed for about an hour from taking off due to traffic control procedures at the destination airport. But once in the air, the flight went well. The crew members were great and provided cabin service despite moderate turbulence during much of the flight.

it was a very short flight so my expectations were low.

As great a red-eye flight as red-eye flights can be.

Very old flight - time to retire it for newer airplanes

Everything you need to know for your flight from Charleston to Des Moines

Information on your arrival and departure airports

Charleston (CRW)
Des Moines (DSM)