CHI - SCL

$286 Find Cheap Flights from Chicago to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Chicago to Santiago departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to Santiago.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to Santiago.
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Everything you should know

Cheapest round-trip
$655
Delta
Tue 3/10Tue 3/17
MDW - SCL • 2 stops
Cheapest one-way
$286
Typical prices: $355-$410
Avianca
Mon 1/19
ORD - SCL • 1 stop
Top airlines
Delta
Cheapest • from $655 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
2 weeks
in advance
Our data shows that travelers who book at least 2 weeks in advance save around 25% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
September
Cheapest • 22% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Chicago to Santiago (CHI-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Chicago to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Chicago to Santiago

Tue, Mar 10 - Tue, Mar 17
Delta Logo
1:09 pm - 7:40 am
MDW
-
SCL
16h 31m2 stops
Delta Logo
10:10 pm - 12:29 pm
SCL
-
MDW
16h 19m2 stops
$655Delta
Tue, Mar 10 - Tue, Mar 17
Delta Logo
9:43 am - 7:00 am
ORD
-
SCL
19h 17m2 stops
Delta Logo
10:10 pm - 1:16 pm
SCL
-
ORD
17h 06m2 stops
$655Delta
Mon, Jan 5 - Mon, Jan 26
Multiple Airlines Logo
6:05 pm - 6:40 am
ORD
-
SCL
33h 35m2 stops
Multiple Airlines Logo
12:35 pm - 11:22 am
SCL
-
ORD
25h 47m2 stops
$664Multiple Airlines
Tue, Jan 27 - Wed, Feb 11
LATAM Airlines Logo
10:48 am - 7:40 am
MDW
-
SCL
17h 52m1 stop
LATAM Airlines Logo
11:10 pm - 5:45 pm
SCL
-
MDW
21h 35m1 stop
$670LATAM Airlines
Mon, Jan 5 - Mon, Jan 26
Multiple Airlines Logo
6:05 pm - 10:15 pm
ORD
-
SCL
25h 10m2 stops
Multiple Airlines Logo
9:05 pm - 10:38 pm
SCL
-
ORD
28h 33m3 stops
$675Multiple Airlines
Thu, Mar 19 - Sun, Mar 29
LATAM Airlines Logo
12:47 pm - 7:40 am
MDW
-
SCL
16h 53m1 stop
LATAM Airlines Logo
8:40 pm - 10:29 pm
SCL
-
MDW
27h 49m1 stop
$678LATAM Airlines
Thu, Mar 19 - Sun, Mar 29
LATAM Airlines Logo
11:15 am - 7:40 am
ORD
-
SCL
18h 25m1 stop
LATAM Airlines Logo
8:40 pm - 6:46 pm
SCL
-
ORD
24h 06m1 stop
$678LATAM Airlines
Fri, Mar 13 - Sat, Mar 21
LATAM Airlines Logo
5:38 pm - 7:40 am
MDW
-
SCL
12h 02m1 stop
LATAM Airlines Logo
10:35 am - 9:55 am
SCL
-
MDW
25h 20m2 stops
$680LATAM Airlines
Sun, Mar 22 - Sat, Mar 28
LATAM Airlines Logo
5:40 am - 7:40 am
ORD
-
SCL
24h 00m1 stop
LATAM Airlines Logo
10:10 pm - 10:05 am
SCL
-
ORD
13h 55m1 stop
$680LATAM Airlines
Wed, Mar 11 - Sat, Mar 21
Delta Logo
12:47 pm - 7:40 am
MDW
-
SCL
16h 53m1 stop
Delta Logo
6:35 pm - 12:02 pm
SCL
-
MDW
19h 27m2 stops
$761Delta
Booking Insights

KAYAK's insights & trends for Chicago to Santiago flights

Get data-powered insights and trends into flights from Chicago to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Chicago to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Chicago to Santiago departing in March.

What’s the cheapest day of the week to fly from Chicago to Santiago?

The average price of all round-trip flights from Chicago to Santiago clicked on KAYAK for each day over the last 12 months.

When flying from Chicago to Santiago, you should consider leaving on a Tuesday and avoid Saturdays if you are looking for the best rates. For your return to Chicago, you’ll find the best rates on Wednesdays and the most expensive ones on Mondays.

What is the cheapest month to fly from Chicago to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago to Santiago is September, where tickets cost $659 (return) on average. On the other hand, the most expensive months are March and December, where the average cost of round-trip tickets is $962 and $926 respectively.

How far in advance should I book a flight from Chicago to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Chicago to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Chicago to Santiago, you should book around 2 weeks before departure, which saves you about 25% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 23 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$286
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly with an average 9% increase in price.
Flight from Chicago O'Hare Airport to Santiago

When to book flights from Chicago to Santiago

Are your dates flexible? Find out the best times to travel from Chicago to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Chicago to Santiago

  • Which airlines from Chicago to Santiago have the Unaccompanied Minor service?

    American Airlines provides an Unaccompanied Minor (UM) service for kids flying alone on flights from Chicago to Santiago. Children between the ages of 5 and 14 can use the service. Parents must fill out the relevant documentation, sign the Unaccompanied Minor form, and produce a legitimate form of identification. American Airlines ensures that minors traveling alone are monitored by devoted staff members from check-in to arrival at their destination.

  • Which airlines are suitable for families flying from Chicago to Santiago?

    American Airlines is a great option for family flights between Chicago and Santiago. Families traveling with youngsters can take advantage of American Airlines' perks, including priority boarding for those with strollers, complimentary meals for kids, and kid-friendly in-flight entertainment. Additionally, their airport lounges provide aid with stroller storage and feature family-friendly facilities like dedicated family rooms equipped with comfortable seating, televisions, and toys for kids to play with.

  • What is the most sustainable airline from Chicago to Santiago?

    When flying from Chicago to Santiago, Delta is one of the sustainable airlines to consider. In addition to investing in fuel-efficient aircraft, Delta has started carbon offset programs and waste reduction initiatives. Additionally, they participate in research projects on biofuels that aim to create and utilize environmentally friendly jet fuel. Delta has also committed to lowering the usage of single-use plastics and actively recycling waste generated while traveling.

  • Which airlines offer business- and first-class flights from Chicago to Santiago?

    American Airlines and LATAM Airlines provide first- and business-class services from Chicago to Santiago. American Airlines' business-class service offers lie-flat seats, premium dining options, access to their Admirals Club lounges, priority boarding, and dedicated customer service. LATAM offers entirely flat beds, priority check-in and boarding, access to VIP lounges, great cuisine, and a large range of wines and spirits as part of their business-class service.

  • What is the cheapest flight from Chicago to Santiago?

    In the last 3 days, the lowest price for a flight from Chicago to Santiago was $286 for a one-way ticket and $655 for a round-trip.

  • Do I need a passport to fly between Chicago and Santiago?

    Yes, you’ll need a passport to travel to Santiago from Chicago.

  • Which airports will I be using when flying from Chicago to Santiago?

    Chicago is served by 2 major airports and there is only 1 main airport in Santiago. You will leave Chicago from one of these airports: Chicago Midway or Chicago O'Hare Intl. You will be arriving at Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Chicago to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Chicago to Santiago?

    SkyTeam, oneworld, and Star Alliance are the airline alliances operating flights between Chicago and Santiago, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Chicago to Santiago, Delta or Copa Airlines?

    The two airlines most popular with KAYAK users for flights from Chicago to Santiago are Delta and Copa Airlines. With an average price for the route of $953 and an overall rating of 7.9, Delta is the most popular choice. Copa Airlines is also a great choice for the route, with an average price of $861 and an overall rating of 7.6.

  • How does KAYAK find such low prices on flights from Chicago to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Chicago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Chicago with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Chicago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Chicago to Santiago

  • Passengers looking to visit downtown from Santiago Airport (SCL) can use several buses available at the airport. The Centro Puerto bus leaves Santiago Airport every 30 minutes to downtown. Metro de Santiago bus line 5 runs every 5 minutes from SCL to Santa Ana.
  • Passengers with limited mobility should consider flying with United from Chicago to Santiago. United Airlines offers assistance with boarding and deplaning, wheelchair service, and priority seating. The airline also provides accessible restrooms and the choice of purchasing an Economy Plus seat for more legroom for passengers with limited mobility.
  • Flights from Chicago to Santiago will land at Comodoro Arturo Merino Benítez International Airport (SCL). SCL is a hub for LATAM Airlines, providing passengers with more frequent flight options and easier connections to other cities.
  • Flights from Chicago to Santiago include at least a single layover en route. Most layover cities depend on the airline and departing airport. Delta, United, American Airlines, LATAM Airlines, and Spirit Airlines offer most of the flights on these routes, and the most common layovers are in Dallas, New York, Miami, and Panama cities.
  • LATAM Airlines has one of the most favorable pet policies for flights from Chicago to Santiago. Pets traveling in-cabin must be in a ventilated, leak-proof kennel with enough space for the pet. The kennel and the pet combined should weigh at most 18 lb, and the dimensions should be at most 15.5 x 11.5 x 8.5 inches.

Reviews of the top 5 airlines serving from Chicago to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Chicago to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Chicago to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8013 reviews
7.9Entertainment
8.5Crew
7.3Food
7.9Comfort
8.1Boarding
Airline reviews

The food is terrible. The staff is wonderful. Comfort is good.

10.0 ExcellentRonda, Dec 2025
JAX - JFK
Read more Delta reviews

The food is terrible. The staff is wonderful. Comfort is good.

Left on time, a bit delayed due to headwinds most of the trip.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Getting to the flight was arduous and lengthy. The flight itself was good but the food option wasn’t a good selection. I need to do a Kosher option on my return. Flight crew were nice

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Staff was exceptional! Everyone was kind, professional and friendly making the trip very pleasant. Thank you!

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Check in -- in business took over 30 mins as there was only one attendant. Boarding was also a mess. The seat was too narrow and was not working properly. Food was very bad and the entertainment very poor. Crew was very polite and helpful, in fairness.

we were missing our luggage, trying to find someone to have any empathy was pretty much not happening....

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

The movies offered were great. Staff were very pleasant and very efficient.

After a delay at the gate, C3, at Ohare on Sunday, I left my Blk ski coat on the bench at the gate, lost! Please review my lob claim, thx.

Very nice flight love the small aircraft. We had a wonderful flight attendant. Nice to see someone that really enjoys her job. Don't have her name but had a southern accent.

Very thoughtful flight attendant offered me water immediately since I had run to make my connection.

Seats in waiting area and on plane hard as rock. Fast internet on the flight was great! Crew was kind.

Always wish for more healthy, gluten free options. We have to bring our own.

Having a long layover, I was very appreciative of the ability to stand by for an earlier flight. Other airlines like Delta have refused this to me in the past, just to be mean (because my ticket class wasn't high enough). United went out of their way to help me get to my destination early, which I really appreciated given that it was the third leg of a 24+ hour journey for me.

Other than a way way too cold cabinets for the entire flight, all was great

One bag is incorrect and not acceptable for an international flight. The food was not just good. I won't fly with them again.

Excellent flight. Smooth, efficient boarding. Quick flight. Arrived early at STL.

We loved the steward on the plane. He made the night enjoyable

The plane was late, when we did board the plane was as cold as a freezer. I was freezing the entire flight, no blankets. Lost miserable flight I’ve ever had.

My wife and I love to travel, so we fly a lot. We've already logged 381,075 miles and with practically every major airline. But this flight was very disappointing. It started off well, with no delays and a new plane. But when lunchtime approached, all that good impression was ruined. Instead of white tablecloths, we were offered small, dark placemats, which, as it turned out, were perfectly adequate for the food. All the food offered—and my wife and I only took fish, and the meat—was not just bad, it was downright disgusting and not heated enough. The same applies to the appetizers. This was the first time in many years of traveling that we've been offered such disgusting food.

Lost luggage stuck no clothes and no word after 2 days leaving on cruise no stuff or clothes

3 hour weather delay followed by 1 hour (and counting) maintenance delay. UGH!

After we'd boarded , they canceled the flight. The crew didn't even know , we just all received text messages. Then after they deplaned us , AA was just like "too bad, go F your self, we sure ain't gonna help you"

After a two hour delay, my flight was CANCELLED! No pilot available. Such BS.

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

I wish American Airlines would change the airline industry by loading the plane back to front instead of front to back. Planes would board so much more smoothly and quickly.

I have long legs, my foot was out in the aisle and when a flight attendant came walking by and I didn't notice, instead of saying "excuse me" or anything like that, she kicked my foot. Extremely rude

I like the crew members they're very friendly. Clean plane. The flight was on time. I dont like the comfort my car seat its better that the plane seats. They charge for everything. This airline was very good. Now it's a low cost airline

No free snacks nor drinks on very short 30min flight. Entertainment system is over wifi to your own phone or tablet, which is good but often a show or movie just stops and refuses to continue

I like the crew they're very friendly. I don't like. on five hour flight they not offered snacks. Any drink. Not even coffee

Not even water is offered on the flight. You cannot lean back on the seats and the seats are so narrow you can’t avoid rubbing elbows with the person next to you.

I couldnt recline the seat. Other than that crew was very attentive and helpful. Thsnk you

I had to go to the boarding counter for them to enter my return flight as it’s not with Avianca. There was a long queue as there were lots of people being called to the counter.

This low cost airline looks and fells more like a local bus. In a 6 hour flight not being able to recline a seat is torture. The only thing available with no charge is a glass of water provided by, mostly, rude staff. Our luggage didn’t arrive

Did not fly with Pakistan International Airlines. Have never flown with Pakistan International Airlines.

Boarding, crew were excellent, food was ok and entertainment need to improve

The seats were uncomfortable and barely reclined at all. Very little leg room despite being business class. The crew was friendly and the food was good. Had to use my own phone for in-flight entertainment.

Everything you need to know for your flight from Chicago to Santiago

Information on your arrival and departure airports