CHI - SCL

$205 Find Cheap Flights from Chicago to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Chicago to Santiago departing on 4/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to Santiago.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to Santiago.
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Everything you should know

Cheapest round-trip
$514
Typical prices: $710-$951
Multiple Airlines
Tue 3/17Mon 3/23
ORD - SCL • 3 stops
Cheapest one-way
$205
Typical prices: $290-$454
Multiple Airlines
Sun 4/19
ORD - SCL • 2 stops
Top airlines
Copa Airlines
Cheapest • from $528 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
6 weeks
in advance
Our data shows that travelers who book at least 6 weeks in advance save around 32% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
September
Cheapest • 18% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Chicago to Santiago (CHI-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Chicago to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Chicago to Santiago

Tue, Mar 17 - Mon, Mar 23
Multiple Airlines Logo
10:55 am - 10:15 pm
ORD
-
SCL
33h 20m
3 stops
Multiple Airlines Logo
9:05 pm - 6:31 pm
SCL
-
ORD
23h 26m
2 stops
$514Multiple Airlines
Tue, Mar 17 - Mon, Mar 23
Multiple Airlines Logo
4:51 pm - 10:15 pm
ORD
-
SCL
27h 24m
2 stops
Multiple Airlines Logo
7:15 am - 8:25 am
SCL
-
ORD
27h 10m
2 stops
$517Multiple Airlines
Tue, Mar 24 - Mon, Apr 6
Multiple Airlines Logo
6:36 pm - 1:09 am
ORD
-
SCL
52h 33m
2 stops
Multiple Airlines Logo
11:00 pm - 9:50 am
SCL
-
ORD
35h 50m
1 stop
$521Multiple Airlines
Mon, Mar 30 - Sun, Apr 12
Multiple Airlines Logo
7:56 am - 11:39 pm
ORD
-
SCL
13h 43m
1 stop
Multiple Airlines Logo
8:20 pm - 9:50 am
SCL
-
ORD
38h 30m
2 stops
$526Multiple Airlines
Mon, Apr 13 - Wed, Apr 22
LATAM Airlines Logo
6:21 pm - 1:45 pm
ORD
-
SCL
18h 24m
2 stops
LATAM Airlines Logo
10:55 pm - 5:41 pm
SCL
-
ORD
19h 46m
1 stop
$529LATAM Airlines
Mon, Apr 27 - Mon, May 4
American Airlines Logo
1:54 pm - 7:05 am
ORD
-
SCL
16h 11m
2 stops
American Airlines Logo
8:35 pm - 12:17 pm
SCL
-
ORD
16h 42m
2 stops
$534American Airlines
Sun, Apr 19 - Fri, Apr 24
Avianca Logo
11:20 pm - 2:15 pm
ORD
-
SCL
13h 55m
1 stop
Avianca Logo
6:40 am - 9:20 pm
SCL
-
ORD
15h 40m
1 stop
$537Avianca
Wed, May 6 - Sat, May 16
LATAM Airlines Logo
12:53 pm - 6:55 am
MDW
-
SCL
17h 02m
2 stops
LATAM Airlines Logo
8:40 pm - 9:51 am
SCL
-
MDW
14h 11m
1 stop
$544LATAM Airlines
Sat, Apr 25 - Sun, May 24
Delta Logo
1:23 pm - 7:15 am
MDW
-
SCL
16h 52m
2 stops
Delta Logo
8:40 pm - 11:56 am
SCL
-
MDW
16h 16m
1 stop
$545Delta
Thu, May 14 - Fri, May 22
Delta Logo
5:14 pm - 7:15 am
MDW
-
SCL
13h 01m
1 stop
Delta Logo
8:40 pm - 9:51 am
SCL
-
MDW
14h 11m
1 stop
$551Delta
Booking Insights

KAYAK's insights & trends for Chicago to Santiago flights

Get data-powered insights and trends into flights from Chicago to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Chicago to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Chicago to Santiago departing in March.

What is the cheapest month to fly from Chicago to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago to Santiago is September, where tickets cost $659 (return) on average. On the other hand, the most expensive months are December and July, where the average cost of round-trip tickets is $940 and $882 respectively.

How far in advance should I book a flight from Chicago to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Chicago to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Chicago to Santiago, you should book around 6 weeks before departure, which saves you about 32% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$205
Best time to beat the crowds with an average 18% drop in price.
Most popular time to fly with an average 17% increase in price.
Flight from Chicago O'Hare Airport to Santiago

When to book flights from Chicago to Santiago

Are your dates flexible? Find out the best times to travel from Chicago to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Chicago to Santiago

  • Which airlines from Chicago to Santiago have the Unaccompanied Minor service?

    American Airlines provides an Unaccompanied Minor (UM) service for kids flying alone on flights from Chicago to Santiago. Children between the ages of 5 and 14 can use the service. Parents must fill out the relevant documentation, sign the Unaccompanied Minor form, and produce a legitimate form of identification. American Airlines ensures that minors traveling alone are monitored by devoted staff members from check-in to arrival at their destination.

  • Which airlines are suitable for families flying from Chicago to Santiago?

    American Airlines is a great option for family flights between Chicago and Santiago. Families traveling with youngsters can take advantage of American Airlines' perks, including priority boarding for those with strollers, complimentary meals for kids, and kid-friendly in-flight entertainment. Additionally, their airport lounges provide aid with stroller storage and feature family-friendly facilities like dedicated family rooms equipped with comfortable seating, televisions, and toys for kids to play with.

  • What is the most sustainable airline from Chicago to Santiago?

    When flying from Chicago to Santiago, Delta is one of the sustainable airlines to consider. In addition to investing in fuel-efficient aircraft, Delta has started carbon offset programs and waste reduction initiatives. Additionally, they participate in research projects on biofuels that aim to create and utilize environmentally friendly jet fuel. Delta has also committed to lowering the usage of single-use plastics and actively recycling waste generated while traveling.

  • Which airlines offer business- and first-class flights from Chicago to Santiago?

    American Airlines and LATAM Airlines provide first- and business-class services from Chicago to Santiago. American Airlines' business-class service offers lie-flat seats, premium dining options, access to their Admirals Club lounges, priority boarding, and dedicated customer service. LATAM offers entirely flat beds, priority check-in and boarding, access to VIP lounges, great cuisine, and a large range of wines and spirits as part of their business-class service.

  • What is the cheapest flight from Chicago to Santiago?

    In the last 3 days, the lowest price for a flight from Chicago to Santiago was $205 for a one-way ticket and $514 for a round-trip.

  • Do I need a passport to fly between Chicago and Santiago?

    Yes, you’ll need a passport to travel to Santiago from Chicago.

  • Which airports will I be using when flying from Chicago to Santiago?

    Chicago is served by 2 major airports and there is only 1 main airport in Santiago. You will leave Chicago from one of these airports: Chicago Midway or Chicago O'Hare Intl. You will be arriving at Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Chicago to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Chicago to Santiago?

    SkyTeam, oneworld, and Star Alliance are the airline alliances operating flights between Chicago and Santiago, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Chicago to Santiago, Delta or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Chicago to Santiago are Delta and LATAM Airlines. With an average price for the route of $893 and an overall rating of 7.9, Delta is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $838 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Chicago to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Chicago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Chicago with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Chicago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Chicago to Santiago

  • Passengers looking to visit downtown from Santiago Airport (SCL) can use several buses available at the airport. The Centro Puerto bus leaves Santiago Airport every 30 minutes to downtown. Metro de Santiago bus line 5 runs every 5 minutes from SCL to Santa Ana.
  • Passengers with limited mobility should consider flying with United from Chicago to Santiago. United Airlines offers assistance with boarding and deplaning, wheelchair service, and priority seating. The airline also provides accessible restrooms and the choice of purchasing an Economy Plus seat for more legroom for passengers with limited mobility.
  • Flights from Chicago to Santiago will land at Comodoro Arturo Merino Benítez International Airport (SCL). SCL is a hub for LATAM Airlines, providing passengers with more frequent flight options and easier connections to other cities.
  • Flights from Chicago to Santiago include at least a single layover en route. Most layover cities depend on the airline and departing airport. Delta, United, American Airlines, LATAM Airlines, and Spirit Airlines offer most of the flights on these routes, and the most common layovers are in Dallas, New York, Miami, and Panama cities.
  • LATAM Airlines has one of the most favorable pet policies for flights from Chicago to Santiago. Pets traveling in-cabin must be in a ventilated, leak-proof kennel with enough space for the pet. The kennel and the pet combined should weigh at most 18 lb, and the dimensions should be at most 15.5 x 11.5 x 8.5 inches.

Reviews of the top 5 airlines serving from Chicago to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Chicago to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Chicago to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8180 reviews
7.2Food
8.1Boarding
8.5Crew
7.9Comfort
7.8Entertainment
Airline reviews

Was forced to check in my small carry on, even though I informed the crew it has very fragile items inside

2.0 MediocreJaspreet, Feb 2026
SEA - SMF
Read more Delta reviews

Was forced to check in my small carry on, even though I informed the crew it has very fragile items inside

This was one of the worst flights I’ve been on in years. I upgraded to comfort and had such an uncomfortable experience. The person next to me was oversized - which I understand - however, they took up their space and mine. I could only use about 50% of my seat space to not be physically touching this person the entire flight and there was no spatial awareness. I also could not use the seat outlet because their body was obstructing it. It was very inconvenient. Their body kept touching me repeatedly during the flight and I felt very uncomfortable. To pay more for an upgraded space and then not even being able to use it was highly disappointing.

No wheel chair as requested at Atlanta arrival on first flight.

Only freetext wifi was available in flight; browsing WiFi required payment. Since the seats had no in flight entertainment, Delta should revisit this policy on this longer flight.

Only water, tea or coffee served midflight, even to comfort seating. Man next to me needed two seats and took up a portion of my seat and Delta did nothing.

The flight was great as well as the airline staff

First class and monitors weren’t working for mine & my husbands. Eventually fixed, but quite annoyed as we bought first class. Also, No foot rests.

Prior to takeoff, the pilot told us there was a possibility of not being able to land and going to Portland. Well that happened, we took off and then did 8 loops around Spokane before the pilot told us we ran out of fuel and had to go to Portland. So for a 35 minute flight we have now been on the plane for 3 hours (boarded at 6:50 am and landed in Portland at 10:30). Then, we just sat in Portland's airport with no updates of when we can start heading back. All of a sudden, our pilots and crew just left, leaving us stranded in a different city and state. We continued to sit in Portland until we finally got a new crew assigned and boarded the plane (This was from 10:30-2). We then sat on the plane for an additional hour before take off because they had to count us multiple times. We finally landed in Spokane at 3:55 PM. So a flight that should have taken at max an hour took us 10 hours and we missed the majority of the recruiting event we went for.

It was delayed but other than that it was great.

Got on the plane and sat there for an hour before departure.

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We were not allowed to carry a bottle of water onto the 8 hour flight.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

Not being stranded in Chicago for her airport to 11:30 tomorrow morning the 3rd

I was fully checked in the prior night and i was unchecked and then didn’t have a seat when I boarded. Instead of an aisle seat, I was out in the middle seat of the very last row of the plane.

In overall it was a good experience, the only down point was that the entertainment screen was working properly.

They lost my luggage, so, not happy. The crew was nice but my suitcases never made it, still trying to find out what happened!

I understand weather is an issue, but making us chase our plane down at five scheduled gates across three terminals in an airport the size of O'Hare was unfair. They'd have probably been better off to leave gates as TBD until the inbound plane is in final approach instead of running us all over the place. Also, props to the consistently-unprepared ground crew in Richmond for once again leaving my lane parked short of the gate because they couldn't have a crew in place on time with 2 hours notice...

cabin crew was OK, food was OK, the trip from the US to Munich was actually pretty bad comfort wise. Noisy aircraft, lights never dimmed even in Business class (night flight) barely sufficient amenities for the price. I have millions of miles with United but TBH American is gaining ground and Delta has always been marginally better then United although on paper United has more longes and cheaper upgrades.

Essy to get on. The hostess gave very little pop, the plane was late getting in, and we are still waiting for our bags. This sucks. :/

Not United Airlines' fault. It's ORL airport's fault.

Great flight. On time boarding. Smooth flight and on time arrival at EWR. The flight crew was marvelous and there was a great selection of movies on the entertainment system. Our bags were at the carousel before we got there. Another excellent flight from United.

I liked the snacks and the flight attendants were friendly.

Delayed an hour due to operational issues. Minimal apologies or care for the significant inconvenience caused. Landed at nearly 1am and they still couldn’t find ground staff to get us off the plane promptly.

The aircraft had several problems - from excess fuel to non operational ac. Two hours of delay in Chicago could have been avoided with proper planning and aircraft maintenance.

Crew in Columbia was not prepared for landing. It was a bit of a disaster and getting bags took forever.

We were upgraded to First Class and it was a great flight

We experienced gate changes and a long delay. My seat was dirty when I boarded and I had to use wipes to clean it myself. There was an unpleasant and overpowering cleaning product scent on the plane as well that lingered through the flight.

My carry on baggage was damaged. Entire trip, I had to carry the baggage. When complained to the boarding crew, they got mad at me and still asked me to valet check in the cabin baggage. Rude boarding crew!!!

Crew were all friendly and helpful. It was a short flight so just a beverage service with a cookie. After we were boarded the plane took about 45 minutes to leave the gate but it was New Year’s Eve so not shocking there was some delay. Overall good experience and very grateful.

The boarding process needs to be fixed. The zone don't work, especially when there is hardly anyone in zones 3, 4,and 5, leaving the majority of the passengers backed up in the aisle, especially because passengers seated near the front are blocking passengers who are seated in the rear of the plane. It would also help if the size of carry on bags was more strictly enforced.

The boarding by groups is pointless. The first two groups worked fine, but almost Noone boarded in goups three thru five leaving the vast majority boarding when group six was called. It defeated the purpose of spreading out the crowd.

We loved the steward on the plane. He made the night enjoyable

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

The flight attendant smashed her beverage cart into my knee, causing significant amount of pain. The seats were extremely uncomfortable. No food or drink is offered unless you want to pay the ridiculous prices for it. The schedule of flying in the overnight hours is also very uncomfortable.

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

No free snacks nor drinks on very short 30min flight. Entertainment system is over wifi to your own phone or tablet, which is good but often a show or movie just stops and refuses to continue

Everything you need to know for your flight from Chicago to Santiago

Information on your arrival and departure airports