Find Cheap Flights from Chicago to South America

Round-trip
Economy
Chicago (CHI)
South America
Thu 11/21
Thu 11/28
Any month
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Chicago to South America Flight Information

Flights Arrive in South America
Flights Depart from Chicago
Flight Price $272
Airlines Spirit Airlines, Copa Airlines, JetBlue, Interjet, Aeromexico, Delta, British Airways, American Airlines, Air Canada

FAQs for Booking Chicago to South America Flights

How does KAYAK find such low flight prices?
KAYAK processes over 2 billion travel queries annually and displays results from hundreds of airlines and third party sites, allowing it to find a variety of flight prices and options. It also displays results from 2M+ properties along with rental cars, vacation packages, activities and millions of verified reviews so users can see as many available travel options as possible.
How can Hacker Fares save me money?
Hacker Fares allow you to combine one-way tickets on different airlines when it can save you money over a traditional round-trip ticket.
Does KAYAK query more flight providers than competitors?
Yes, KAYAK has access to more data and information than online travel agencies and consistently outperforms the competition in accuracy, globally.
How does KAYAK’s flight Price Forecast tool help me choose the right time to buy?
KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a given destination and date is likely to change within 7 days, so travelers know whether to wait or book now.

Book cheap flights from Chicago to South America (round-trip)

Airports
Origin
Chicago
$272
only
$272
Destination
Cali
$275
only
$275
Guayaquil
$384
only
$384
Cartagena
$272
only
$272
Quito
$411
only
$411
Medellín
$316
only
$316
Bogotá
$419
only
$419
Barranquilla
$446
only
$446
Wed, Feb 5
ORD
Chicago O'Hare Intl
CTG
Cartagena Rafael Nunez
7h 19m
Wed, Feb 12
CTG
Cartagena Rafael Nunez
ORD
Chicago O'Hare Intl
10h 29m
Trip: 8 days
Overall null null
Based on null reviews
Thu, Feb 6
ORD
Chicago O'Hare Intl
CTG
Cartagena Rafael Nunez
7h 47m
Tue, Feb 11
CTG
Cartagena Rafael Nunez
ORD
Chicago O'Hare Intl
10h 50m
Trip: 6 days
Overall null null
Based on null reviews
Tue, Mar 10
ORD
Chicago O'Hare Intl
CTG
Cartagena Rafael Nunez
9h 30m
Tue, Mar 17
CTG
Cartagena Rafael Nunez
ORD
Chicago O'Hare Intl
9h 00m
Trip: 8 days
Overall null null
Based on null reviews
Fri, Apr 24
ORD
Chicago O'Hare Intl
MDE
Medellín Jose Marie Cordova & other airports
29h 25m
Mon, Apr 27
MDE
Medellín Jose Marie Cordova & other airports
ORD
Chicago O'Hare Intl
19h 10m
Trip: 4 days
Overall null null
Based on null reviews
Wed, Nov 20
ORD
Chicago O'Hare Intl
UIO
Quito Mariscal Sucr
15h 06m
Wed, Nov 27
UIO
Quito Mariscal Sucr
ORD
Chicago O'Hare Intl
14h 58m
Trip: 8 days
Overall null null
Based on null reviews
Fri, Apr 24
ORD
Chicago O'Hare Intl
UIO
Quito Mariscal Sucr
16h 14m
Sat, May 9
UIO
Quito Mariscal Sucr
ORD
Chicago O'Hare Intl
11h 57m
Trip: 16 days
Overall null null
Based on null reviews
Mon, Nov 18
ORD
Chicago O'Hare Intl
BAQ
Barranquilla E Cortissoz
7h 04m
Mon, Nov 25
BAQ
Barranquilla E Cortissoz
ORD
Chicago O'Hare Intl
20h 18m
Trip: 8 days
Overall null null
Based on null reviews
Tue, Jan 28
ORD
Chicago O'Hare Intl
CLO
Cali Alfonso B. Aragon Intl
15h 23m
Wed, Feb 5
CLO
Cali Alfonso B. Aragon Intl
ORD
Chicago O'Hare Intl
18h 05m
Trip: 9 days
Overall null null
Based on null reviews
Thu, Oct 31
ORD
Chicago O'Hare Intl
BAQ
Barranquilla E Cortissoz
7h 09m
Tue, Nov 5
BAQ
Barranquilla E Cortissoz
ORD
Chicago O'Hare Intl
10h 51m
Trip: 6 days
Overall null null
Based on null reviews
Tue, Nov 5
ORD
Chicago O'Hare Intl
CTG
Cartagena Rafael Nunez
7h 40m
Sat, Nov 9
CTG
Cartagena Rafael Nunez
ORD
Chicago O'Hare Intl
11h 24m
Trip: 5 days
Overall null null
Based on null reviews
Sun, Dec 8
ORD
Chicago O'Hare Intl
CTG
Cartagena Rafael Nunez
7h 20m
Tue, Dec 10
CTG
Cartagena Rafael Nunez
ORD
Chicago O'Hare Intl
10h 02m
Trip: 3 days
Overall null null
Based on null reviews
Thu, Feb 20
ORD
Chicago O'Hare Intl
GYE
Guayaquil Jose Joaquin de Olmedo
18h 20m
Mon, Mar 2
GYE
Guayaquil Jose Joaquin de Olmedo
ORD
Chicago O'Hare Intl
28h 45m
Trip: 12 days
Overall null null
Based on null reviews
Mon, Nov 11
ORD
Chicago O'Hare Intl
CLO
Cali Alfonso B. Aragon Intl
17h 07m
Thu, Nov 14
CLO
Cali Alfonso B. Aragon Intl
ORD
Chicago O'Hare Intl
17h 59m
Trip: 4 days
Overall null null
Based on null reviews
Sun, Mar 29
ORD
Chicago O'Hare Intl
UIO
Quito Mariscal Sucr
12h 20m
Mon, Apr 6
UIO
Quito Mariscal Sucr
ORD
Chicago O'Hare Intl
11h 15m
Trip: 9 days
Overall null null
Based on null reviews
Thu, Jan 9
ORD
Chicago O'Hare Intl
UIO
Quito Mariscal Sucr
16h 11m
Fri, Jan 17
UIO
Quito Mariscal Sucr
ORD
Chicago O'Hare Intl
14h 58m
Trip: 9 days
Overall null null
Based on null reviews
Tue, Jan 14
ORD
Chicago O'Hare Intl
BAQ
Barranquilla E Cortissoz
21h 54m
Sat, Feb 1
BAQ
Barranquilla E Cortissoz
ORD
Chicago O'Hare Intl
18h 11m
Trip: 19 days
Overall null null
Based on null reviews
Sat, Jan 25
ORD
Chicago O'Hare Intl
UIO
Quito Mariscal Sucr
15h 06m
Tue, Jan 28
UIO
Quito Mariscal Sucr
ORD
Chicago O'Hare Intl
28h 24m
Trip: 4 days
Overall null null
Based on null reviews
Wed, Mar 18
ORD
Chicago O'Hare Intl
BOG
Bogotá El Dorado
14h 45m
Thu, Mar 26
BOG
Bogotá El Dorado
ORD
Chicago O'Hare Intl
23h 50m
Trip: 9 days
Overall null null
Based on null reviews
Thu, Jan 16
ORD
Chicago O'Hare Intl
MDE
Medellín Jose Marie Cordova & other airports
8h 05m
Tue, Jan 28
MDE
Medellín Jose Marie Cordova & other airports
ORD
Chicago O'Hare Intl
9h 48m
Trip: 13 days
Overall null null
Based on null reviews
Wed, Apr 1
ORD
Chicago O'Hare Intl
CTG
Cartagena Rafael Nunez
7h 47m
Wed, Apr 15
CTG
Cartagena Rafael Nunez
ORD
Chicago O'Hare Intl
9h 00m
Trip: 15 days
Overall null null
Based on null reviews
*
Prices are per person and are for e–tickets and include all taxes & fees in USD.

We attempt to get accurate prices, however, prices are not guaranteed.

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We’re not the seller.
At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

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Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

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