CHI - SCL

$295 Find Cheap Flights from Chicago to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Chicago to Santiago departing on 9/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to Santiago.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to Santiago.
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Everything you should know

Cheapest round-trip
$619
Typical prices: $1,063-$751
Multiple Airlines
Tue 9/1Tue 9/15
ORD - SCL • 2 stops
Cheapest one-way
$295
Typical prices: $438-$648
Multiple Airlines
Thu 9/3
ORD - SCL • 2 stops
Top airlines
Cheapest • from $661 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Chicago and Santiago. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $764 (round-trip)
Shortest trip • 12h 35m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 4 weeks in advance save around 22% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 30% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Chicago to Santiago (CHI-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Chicago to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Chicago to Santiago

Tue, Sep 1 - Tue, Sep 15
Multiple Airlines Logo
5:30 pm - 2:56 am
ORD
-
SCL
32h 26m
2 stops
Multiple Airlines Logo
10:55 pm - 5:13 pm
SCL
-
ORD
20h 18m
1 stop
$619Multiple Airlines
Mon, Aug 17 - Wed, Aug 26
Multiple Airlines Logo
5:13 pm - 3:00 am
ORD
-
SCL
32h 47m
2 stops
Multiple Airlines Logo
10:55 pm - 5:06 pm
SCL
-
ORD
19h 11m
1 stop
$621Multiple Airlines
Wed, Oct 28 - Tue, Nov 3
Multiple Airlines Logo
4:44 pm - 2:57 am
ORD
-
SCL
32h 13m
2 stops
Multiple Airlines Logo
1:02 am - 12:46 pm
SCL
-
ORD
14h 44m
1 stop
$622Multiple Airlines
Fri, Jul 17 - Wed, Jul 29
Delta Logo
5:10 pm - 7:15 am
MDW
-
SCL
13h 05m
1 stop
Delta Logo
8:40 pm - 4:15 pm
SCL
-
MDW
20h 35m
1 stop
$726Delta
Mon, Oct 19 - Sun, Oct 25
Delta Logo
5:25 pm - 8:15 am
MDW
-
SCL
12h 50m
1 stop
Delta Logo
11:10 pm - 11:56 am
SCL
-
MDW
14h 46m
1 stop
$735Delta
Sun, Oct 4 - Wed, Oct 7
LATAM Airlines Logo
5:10 pm - 8:15 am
MDW
-
SCL
13h 05m
1 stop
LATAM Airlines Logo
3:20 pm - 9:52 am
SCL
-
MDW
20h 32m
2 stops
$737LATAM Airlines
Tue, Jul 14 - Tue, Jul 21
LATAM Airlines Logo
5:10 pm - 7:15 am
MDW
-
SCL
13h 05m
1 stop
LATAM Airlines Logo
11:05 pm - 10:15 pm
SCL
-
MDW
24h 10m
2 stops
$738LATAM Airlines
Tue, Jul 14 - Tue, Jul 21
LATAM Airlines Logo
5:10 pm - 7:15 am
MDW
-
SCL
13h 05m
1 stop
LATAM Airlines Logo
11:05 pm - 10:15 pm
SCL
-
MDW
24h 10m
2 stops
$739LATAM Airlines
Sat, Aug 1 - Sun, Aug 9
Delta Logo
1:18 pm - 6:25 am
MDW
-
SCL
16h 07m
2 stops
Delta Logo
8:40 pm - 9:59 am
SCL
-
MDW
14h 19m
1 stop
$740Delta
Sun, Jun 28 - Sun, Jul 5
LATAM Airlines Logo
6:00 am - 7:15 am
MDW
-
SCL
24h 15m
1 stop
LATAM Airlines Logo
8:40 pm - 12:05 pm
SCL
-
MDW
16h 25m
1 stop
$744LATAM Airlines
Booking Insights

KAYAK's insights & trends for Chicago to Santiago flights

Get data-powered insights and trends into flights from Chicago to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Chicago to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Chicago to Santiago departing in September.

What is the cheapest month to fly from Chicago to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago to Santiago is March, where tickets cost $302 (return) on average. On the other hand, the most expensive months are November and February, where the average cost of round-trip tickets is $626 and $597 respectively.

How far in advance should I book a flight from Chicago to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Chicago to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Chicago to Santiago, you should book around 4 weeks before departure, which saves you about 22% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 15 weeks before departure.

Good to know

Low seasonOctober
Cheapest flight$295
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 17% increase in price.
Flight from Chicago O'Hare Airport to Santiago

When to book flights from Chicago to Santiago

Are your dates flexible? Find out the best times to travel from Chicago to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Chicago to Santiago

  • Which airlines from Chicago to Santiago have the Unaccompanied Minor service?

    American Airlines provides an Unaccompanied Minor (UM) service for kids flying alone on flights from Chicago to Santiago. Children between the ages of 5 and 14 can use the service. Parents must fill out the relevant documentation, sign the Unaccompanied Minor form, and produce a legitimate form of identification. American Airlines ensures that minors traveling alone are monitored by devoted staff members from check-in to arrival at their destination.

  • Which airlines are suitable for families flying from Chicago to Santiago?

    American Airlines is a great option for family flights between Chicago and Santiago. Families traveling with youngsters can take advantage of American Airlines' perks, including priority boarding for those with strollers, complimentary meals for kids, and kid-friendly in-flight entertainment. Additionally, their airport lounges provide aid with stroller storage and feature family-friendly facilities like dedicated family rooms equipped with comfortable seating, televisions, and toys for kids to play with.

  • What is the most sustainable airline from Chicago to Santiago?

    When flying from Chicago to Santiago, Delta is one of the sustainable airlines to consider. In addition to investing in fuel-efficient aircraft, Delta has started carbon offset programs and waste reduction initiatives. Additionally, they participate in research projects on biofuels that aim to create and utilize environmentally friendly jet fuel. Delta has also committed to lowering the usage of single-use plastics and actively recycling waste generated while traveling.

  • Which airlines offer business- and first-class flights from Chicago to Santiago?

    American Airlines and LATAM Airlines provide first- and business-class services from Chicago to Santiago. American Airlines' business-class service offers lie-flat seats, premium dining options, access to their Admirals Club lounges, priority boarding, and dedicated customer service. LATAM offers entirely flat beds, priority check-in and boarding, access to VIP lounges, great cuisine, and a large range of wines and spirits as part of their business-class service.

  • What is the cheapest flight from Chicago to Santiago?

    In the last 7 days, the lowest price for a flight from Chicago to Santiago was $295 for a one-way ticket and $619 for a round-trip.

  • Do I need a passport to fly between Chicago and Santiago?

    Yes, you’ll need a passport to travel to Santiago from Chicago.

  • Which airports will I be using when flying from Chicago to Santiago?

    Chicago is served by 2 major airports and there is only 1 main airport in Santiago. You will leave Chicago from one of these airports: Chicago Midway or Chicago O'Hare Intl. You will be arriving at Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Chicago to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Chicago to Santiago?

    SkyTeam, oneworld, and Star Alliance are the airline alliances operating flights between Chicago and Santiago, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Chicago to Santiago, Delta or Copa Airlines?

    The two airlines most popular with KAYAK users for flights from Chicago to Santiago are Delta and Copa Airlines. With an average price for the route of $903 and an overall rating of 7.9, Delta is the most popular choice. Copa Airlines is also a great choice for the route, with an average price of $737 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Chicago to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Chicago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Chicago with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Chicago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Chicago to Santiago

  • Passengers looking to visit downtown from Santiago Airport (SCL) can use several buses available at the airport. The Centro Puerto bus leaves Santiago Airport every 30 minutes to downtown. Metro de Santiago bus line 5 runs every 5 minutes from SCL to Santa Ana.
  • Passengers with limited mobility should consider flying with United from Chicago to Santiago. United Airlines offers assistance with boarding and deplaning, wheelchair service, and priority seating. The airline also provides accessible restrooms and the choice of purchasing an Economy Plus seat for more legroom for passengers with limited mobility.
  • Flights from Chicago to Santiago will land at Comodoro Arturo Merino Benítez International Airport (SCL). SCL is a hub for LATAM Airlines, providing passengers with more frequent flight options and easier connections to other cities.
  • Flights from Chicago to Santiago include at least a single layover en route. Most layover cities depend on the airline and departing airport. Delta, United, American Airlines, LATAM Airlines, and Spirit Airlines offer most of the flights on these routes, and the most common layovers are in Dallas, New York, Miami, and Panama cities.
  • LATAM Airlines has one of the most favorable pet policies for flights from Chicago to Santiago. Pets traveling in-cabin must be in a ventilated, leak-proof kennel with enough space for the pet. The kennel and the pet combined should weigh at most 18 lb, and the dimensions should be at most 15.5 x 11.5 x 8.5 inches.

Reviews of the top 5 airlines serving from Chicago to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Chicago to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Chicago to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8400 reviews
8.1Boarding
7.8Entertainment
8.5Crew
7.8Comfort
7.2Food
Airline reviews

Average seat comfort, a drink and chips were provided, early boarding because we checked a carryon at the gate was nice. Ticket pricing shenanigans, including fees to pick a seat, check a bag, and get food onboard - evidence the industry is reinvigorating last century’s strategies- destroys the experience before one ever arrives at the airport. It’s difficult to recognize any value or sustain loyalty in the end-to-end process making air travel more drudgery than pleasure.

6.0 GoodDouglas, Jun 2026
SLC - CLT
Read more Delta reviews

Average seat comfort, a drink and chips were provided, early boarding because we checked a carryon at the gate was nice. Ticket pricing shenanigans, including fees to pick a seat, check a bag, and get food onboard - evidence the industry is reinvigorating last century’s strategies- destroys the experience before one ever arrives at the airport. It’s difficult to recognize any value or sustain loyalty in the end-to-end process making air travel more drudgery than pleasure.

Gate agent was unhelpful for handicapped boarding. Flight attendant seemed untrained.

No service flight that took 5 hrs and a stop at an unscheduled airport. Crew and pilots did their jobs

Clean planes and not take my comfort class seat away.

The crew were efficient. The pilots seemed professional. It was a bit chilly in our seats. The sheet provided weren’t very helpful.

Weather caused a long delay, but the efficiency and updates from the pilot were helpful. We were able to make our connection fortunately.

Planes were clean, no water or snacks on either flight.

Free & relatively fast Wi-Fi. Would've liked a wider drink selection.

I continue to be satisfied with Delta’s excellent service out of LGA. The digit id works well and gets me through security in no time. Whenever possible, I choose Delta.

Was revoked with Jet Blue due to delay from Kenya Air

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

Boarded early; and arrived home 40 mins early. After a long flight, it’s nice to be back home early. These flights have no amenities; no snacks. So need to bring your own

A long delay. Don't travel late in the day.

Super friendly with lots of drink options an entertainment. Friendly crew.

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

Several missed and almost missed connections. It felt like everything was being patched together last minute without enough resources and it ended up being an extremely stressful experience that basically ruined our weekend on the west coast. What a waste.

Crew was friendly. Seats are too narrow, particularly when a big person is in the adjacent seat, but I understand this is due to smaller planes usually flight into Lincoln. I have experienced several flight delays going out and coming into Lincoln airport, I say maybe 50% or higher of the flights I've taken out of this airport have been delayed.

Great flight. Boarded efficiently. Arrived early at CLT. There was no in flight entertainment on this aircraft. Great crew.

The seat was comfortable. There was a lot of turbulence. If it weren't for that,it would have been okay.

Poor communication, flight was delayed for preventable reasons. I missed my connection.

The boarding timing needs to be improved. The flight was delayed again because it took way too long to board. I was already exhausted from sleeping at the airport and spending all day there due to delay from my previous flight that connected in Chicago.

American Airlines II: Delay Boogaloo. Multiple gate changes, delays, boarded and then MORE delays. I hate to say this won’t matter, but posting stuff about major corporations in 2026 is a post-modern “scream into the void.” Was multiple hours late coming home, so there you go.

Our flight was cancelled while we are on our way to the airport. So, no notice. We were rescheduled to another airline with a 2 hour later takeoff and so arrived at our destination on time. We pre-paid American Airlines $190 to upgrade our seats. No refund. So no use for AA or Kayak.

Terrible, horrible, disappointing- without telling us they changed planes and moved and separated our seats to opposite sides - said they changed seats putting us together - got to airport to find no, they did not - we sat opposing sides of plane - food overly salty to inedible, never saw stewardess but once - it was terrible

The airplane was an old model, the overhead didn’t have enough room for people’s items and made boarding and boarding disappointing and stressful. Crew allowed passengers to bring more than the permitted baggage sizes.

Original flight was on time, then late, then changed gates...4 times. Once our newest plane came in, it was fine.

I almost missed my flight and they helped me out enormously

Delays experienced in boarding/take off due to incoming plane delayed. However, the boarding time/depart time in the app was significantly delayed in providing these updates. Usually not updated until an hour after we should have already boarded. Poorly managed.

Moved to earlier flight which unexpectedly had maintenance issues initially indicated as quick fix to ultimately plane changes. Moved back to original flight, also delayed. In all cases customer updates and communication very unclear, no updates on drivers for delays.

Typical AA - late by 90+ mn. Gate changed twice... Changed the departure time 6 times No explanation, no communication on reasons for delay I travel with AA twice a year... and it is consistently very poor.. I will continue to use AA only when i have to.

The gate got changed several times and the flight was delayed over an hour. Awful experience

The worst experience I've ever had because the "people" @ Avianca wouldn't let me fly because they said I needed a round trip ticket

Seating was tight. Seats don't recline. Initial flight was cancelled. Lost two days of vacation.

I had bad experiences before now was excellent I am glad they have business class again

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

The flight attendant smashed her beverage cart into my knee, causing significant amount of pain. The seats were extremely uncomfortable. No food or drink is offered unless you want to pay the ridiculous prices for it. The schedule of flying in the overnight hours is also very uncomfortable.

Everything you need to know for your flight from Chicago to Santiago

Information on your arrival and departure airports