CHI - SCL

$283 Find Cheap Flights from Chicago to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Chicago to Santiago departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to Santiago.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to Santiago.
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Everything you should know

Cheapest round-trip
$639
Typical prices: $888-$1,318
Multiple Airlines
Tue 8/18Sat 8/22
ORD - SCL • 2 stops
Cheapest one-way
$283
Typical prices: $438-$648
Multiple Airlines
Tue 9/22
ORD - SCL • 2 stops
Top airlines
Cheapest • from $690 (round-trip)
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Chicago and Santiago. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $764 (round-trip)
Shortest trip • 12h 35m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 4 weeks in advance save around 19% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 30% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Chicago to Santiago (CHI-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Chicago to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Chicago to Santiago

Tue, Aug 18 - Sat, Aug 22
Multiple Airlines Logo
5:59 pm - 5:14 am
ORD
-
SCL
34h 15m
2 stops
Multiple Airlines Logo
6:40 am - 9:20 pm
SCL
-
ORD
15h 40m
1 stop
$639Multiple Airlines
Tue, Sep 8 - Tue, Sep 15
Multiple Airlines Logo
7:44 pm - 2:46 am
ORD
-
SCL
29h 02m
2 stops
Multiple Airlines Logo
7:40 am - 9:20 pm
SCL
-
ORD
15h 40m
1 stop
$643Multiple Airlines
Tue, Sep 1 - Wed, Sep 16
Multiple Airlines Logo
7:44 pm - 2:56 am
ORD
-
SCL
30h 12m
2 stops
Multiple Airlines Logo
7:40 am - 9:20 pm
SCL
-
ORD
15h 40m
1 stop
$644Multiple Airlines
Sat, Jul 11 - Fri, Jul 24
Delta Logo
6:00 am - 7:15 am
MDW
-
SCL
24h 15m
1 stop
Delta Logo
8:40 pm - 12:38 pm
SCL
-
MDW
16h 58m
2 stops
$697Delta
Mon, Aug 31 - Thu, Sep 3
LATAM Airlines Logo
6:05 am - 1:35 pm
MDW
-
SCL
30h 30m
2 stops
LATAM Airlines Logo
4:30 pm - 10:36 pm
SCL
-
MDW
31h 06m
2 stops
$704LATAM Airlines
Mon, Aug 31 - Wed, Sep 16
Delta Logo
4:39 pm - 7:15 am
MDW
-
SCL
13h 36m
1 stop
Delta Logo
8:40 pm - 9:50 am
SCL
-
MDW
15h 10m
1 stop
$705Delta
Mon, Aug 31 - Fri, Sep 4
Delta Logo
10:54 am - 6:55 am
MDW
-
SCL
19h 01m
2 stops
Delta Logo
8:40 pm - 4:59 pm
SCL
-
MDW
21h 19m
2 stops
$709Delta
Fri, Aug 28 - Mon, Aug 31
LATAM Airlines Logo
10:54 am - 3:00 pm
MDW
-
SCL
27h 06m
2 stops
LATAM Airlines Logo
11:00 pm - 10:36 pm
SCL
-
MDW
24h 36m
2 stops
$710LATAM Airlines
Fri, Nov 6 - Mon, Nov 16
LATAM Airlines Logo
10:35 am - 6:00 am
MDW
-
SCL
16h 25m
2 stops
LATAM Airlines Logo
11:10 pm - 11:56 am
SCL
-
MDW
15h 46m
1 stop
$715LATAM Airlines
Mon, Sep 7 - Tue, Sep 22
LATAM Airlines Logo
10:54 am - 8:15 am
MDW
-
SCL
19h 21m
1 stop
LATAM Airlines Logo
8:40 pm - 9:53 am
SCL
-
MDW
15h 13m
1 stop
$734LATAM Airlines
Booking Insights

KAYAK's insights & trends for Chicago to Santiago flights

Get data-powered insights and trends into flights from Chicago to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Chicago to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Chicago to Santiago departing in August.

What is the cheapest month to fly from Chicago to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago to Santiago is March, where tickets cost $302 (return) on average. On the other hand, the most expensive months are November and February, where the average cost of round-trip tickets is $626 and $597 respectively.

How far in advance should I book a flight from Chicago to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Chicago to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Chicago to Santiago, you should book around 4 weeks before departure, which saves you about 19% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 15 weeks before departure.

Good to know

Low seasonJune
Cheapest flight$283
Best time to beat the crowds with an average 3% drop in price.
Most popular time to fly with an average 12% increase in price.
Flight from Chicago O'Hare Airport to Santiago

When to book flights from Chicago to Santiago

Are your dates flexible? Find out the best times to travel from Chicago to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Chicago to Santiago

  • Which airlines from Chicago to Santiago have the Unaccompanied Minor service?

    American Airlines provides an Unaccompanied Minor (UM) service for kids flying alone on flights from Chicago to Santiago. Children between the ages of 5 and 14 can use the service. Parents must fill out the relevant documentation, sign the Unaccompanied Minor form, and produce a legitimate form of identification. American Airlines ensures that minors traveling alone are monitored by devoted staff members from check-in to arrival at their destination.

  • Which airlines are suitable for families flying from Chicago to Santiago?

    American Airlines is a great option for family flights between Chicago and Santiago. Families traveling with youngsters can take advantage of American Airlines' perks, including priority boarding for those with strollers, complimentary meals for kids, and kid-friendly in-flight entertainment. Additionally, their airport lounges provide aid with stroller storage and feature family-friendly facilities like dedicated family rooms equipped with comfortable seating, televisions, and toys for kids to play with.

  • What is the most sustainable airline from Chicago to Santiago?

    When flying from Chicago to Santiago, Delta is one of the sustainable airlines to consider. In addition to investing in fuel-efficient aircraft, Delta has started carbon offset programs and waste reduction initiatives. Additionally, they participate in research projects on biofuels that aim to create and utilize environmentally friendly jet fuel. Delta has also committed to lowering the usage of single-use plastics and actively recycling waste generated while traveling.

  • Which airlines offer business- and first-class flights from Chicago to Santiago?

    American Airlines and LATAM Airlines provide first- and business-class services from Chicago to Santiago. American Airlines' business-class service offers lie-flat seats, premium dining options, access to their Admirals Club lounges, priority boarding, and dedicated customer service. LATAM offers entirely flat beds, priority check-in and boarding, access to VIP lounges, great cuisine, and a large range of wines and spirits as part of their business-class service.

  • What is the cheapest flight from Chicago to Santiago?

    In the last 5 days, the lowest price for a flight from Chicago to Santiago was $283 for a one-way ticket and $639 for a round-trip.

  • Do I need a passport to fly between Chicago and Santiago?

    Yes, you’ll need a passport to travel to Santiago from Chicago.

  • Which airports will I be using when flying from Chicago to Santiago?

    Chicago is served by 2 major airports and there is only 1 main airport in Santiago. You will leave Chicago from one of these airports: Chicago Midway or Chicago O'Hare Intl. You will be arriving at Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Chicago to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Chicago to Santiago?

    SkyTeam, oneworld, and Star Alliance are the airline alliances operating flights between Chicago and Santiago, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Chicago to Santiago, Delta or Copa Airlines?

    The two airlines most popular with KAYAK users for flights from Chicago to Santiago are Delta and Copa Airlines. With an average price for the route of $903 and an overall rating of 7.8, Delta is the most popular choice. Copa Airlines is also a great choice for the route, with an average price of $737 and an overall rating of 7.6.

  • How does KAYAK find such low prices on flights from Chicago to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Chicago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Chicago with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Chicago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Chicago to Santiago

  • Passengers looking to visit downtown from Santiago Airport (SCL) can use several buses available at the airport. The Centro Puerto bus leaves Santiago Airport every 30 minutes to downtown. Metro de Santiago bus line 5 runs every 5 minutes from SCL to Santa Ana.
  • Passengers with limited mobility should consider flying with United from Chicago to Santiago. United Airlines offers assistance with boarding and deplaning, wheelchair service, and priority seating. The airline also provides accessible restrooms and the choice of purchasing an Economy Plus seat for more legroom for passengers with limited mobility.
  • Flights from Chicago to Santiago will land at Comodoro Arturo Merino Benítez International Airport (SCL). SCL is a hub for LATAM Airlines, providing passengers with more frequent flight options and easier connections to other cities.
  • Flights from Chicago to Santiago include at least a single layover en route. Most layover cities depend on the airline and departing airport. Delta, United, American Airlines, LATAM Airlines, and Spirit Airlines offer most of the flights on these routes, and the most common layovers are in Dallas, New York, Miami, and Panama cities.
  • LATAM Airlines has one of the most favorable pet policies for flights from Chicago to Santiago. Pets traveling in-cabin must be in a ventilated, leak-proof kennel with enough space for the pet. The kennel and the pet combined should weigh at most 18 lb, and the dimensions should be at most 15.5 x 11.5 x 8.5 inches.

Reviews of the top 5 airlines serving from Chicago to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Chicago to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Chicago to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1569 reviews
7.4Comfort
7.8Boarding
8.1Crew
6.9Food
6.8Entertainment
Airline reviews

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

2.0 MediocreAnonymous, Dec 2025
LAS - PTY
Read more Copa Airlines reviews

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

Placed us in the last rear row of the plane so could not recline seats because of the rear wall, and also made it more of a tight space when the passenger in front reclined their seat. While understand seat assignments, every passenger should be afforded a reclining seat. The odor control scent from the restrooms was overwhelming strong. My wife and I could not deal with it, and she suffered a terrible headache as a result. I kept getting hit by the crew since I was on the ilse seat. No apologies, nothing. They made me feel like I was supposed to take the beating for a 3 hr flight.

There was no individual at the front check in when I arrived. I waited for at least 15 minutes and walked around asking security/janitors if they could help and they did not have a solution. So I had to take my checked bag through security and they threw away some of my items. I ended up making it to the gate only a few minutes before it closed due to my waiting for an agent at check in.

It would have been better if they don't separate families in seating. We were seated in the aile row in the middle of a family of four. It would have been better if they they seat the family of four together than separated.

Well the airline was fine. The only thing is I was charged for a checked in luggage. But when I reserved the ticket it showed a check in bag allowed. Who can I get in contact with for reimbursement.? The airline said I had to speak to whoever I booked ticket with.

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

I liked everything, this was classed as premium economy but it was much better than Lufthansas business class. Lovely staff, comfortable plane and an excellent seat arrangement. A very pleasant surprise.

The crew was amazing. The best in the last times. Great group of people.

I do not read or speak in Spanish. Only English. When asking for help, the people spoke quickly in English and pointed a lot. I wish they would’ve spoken a little slower for me to understand. There was much confusion and hurried in their message and I was unclear as to where to go

It’s been some time since I saw the plane and the cabin that old and worn out.

I loved how polite the crew was even though some of them wasn't the best with English that they still done everything they could to help me with my needs food was amazing

Terrible They charged me 157$ for excess baggage even though my bags were within the normally accepted limits Flight was late. Service was poor. The snacks were really bad

Agents at gate were not immediately available to solve problems and once they did they didn’t fix all the fight connections

Great experience. Boarding was fast, staff were very nice and funny, everything at the seat worked well.

Horrible! Several delays and then was cancelled! I spent over 24 hours in the airport and was unable to get a hotel or food voucher.

Smooth travel. Immediate update prior flight delay so I can arrange myself properly without too rush.

Boarded early; and arrived home 40 mins early. After a long flight, it’s nice to be back home early. These flights have no amenities; no snacks. So need to bring your own

A long delay. Don't travel late in the day.

Super friendly with lots of drink options an entertainment. Friendly crew.

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

Several missed and almost missed connections. It felt like everything was being patched together last minute without enough resources and it ended up being an extremely stressful experience that basically ruined our weekend on the west coast. What a waste.

Crew was friendly. Seats are too narrow, particularly when a big person is in the adjacent seat, but I understand this is due to smaller planes usually flight into Lincoln. I have experienced several flight delays going out and coming into Lincoln airport, I say maybe 50% or higher of the flights I've taken out of this airport have been delayed.

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

The flight was delayed significantly. Communication during the flight was abrupt and caused some panic as we were navigating turbulence. It was also too loud and every announcement felt startling. The flight attendants did not offer any assurances and I felt unsettled most of the flight. The seats, floor and tray table was very dirty. The seat next to me was broken and the passenger sitting there was very uncomfortable. He had a spring in his back and his seat made terrible squeaking noises through the flight.

Significant delays on my trip to Chicago and my trip back to NY

Delayed by 5 hours and I had to wit in the airport for more than 6+ hours.

I’ve got 31F seat and window seat . My 2 co passengers was AA crew members and they were very rude attitude and when I was going to use bathroom their gestures was very different and awkward and the guy beside me completely occupied the hand rest and I was really uncomfortable

It was so much better than expected, Ohare is not such a pleasant experience but American Airlines with the new, clean aeroplane and free Wi-Fi was outstanding and the crew so pleasant and helpful.

It wa sort of on time; the cab was left with some trash

My pillow had a shoe print on it, when I asked if I can have another pillow, I was told “I’m sorry but it is one pillow per guest, do YOU want to turn it inside out” to which I responded , no thanks I will go without. This is generally not ok, but For the price tag I paid flying business this is absolutely unacceptable. Hopefully American Airlines can update their accommodations to bedding that is not tossed on the ground and stepped on, or at least have a couple of extra pillows in hand, incase someone had decided to step on the pillows for what ever reason

American Airlines II: Delay Boogaloo. Multiple gate changes, delays, boarded and then MORE delays. I hate to say this won’t matter, but posting stuff about major corporations in 2026 is a post-modern “scream into the void.” Was multiple hours late coming home, so there you go.

Our flight was cancelled while we are on our way to the airport. So, no notice. We were rescheduled to another airline with a 2 hour later takeoff and so arrived at our destination on time. We pre-paid American Airlines $190 to upgrade our seats. No refund. So no use for AA or Kayak.

The worst experience I've ever had because the "people" @ Avianca wouldn't let me fly because they said I needed a round trip ticket

Seating was tight. Seats don't recline. Initial flight was cancelled. Lost two days of vacation.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

This low cost airline looks and fells more like a local bus. In a 6 hour flight not being able to recline a seat is torture. The only thing available with no charge is a glass of water provided by, mostly, rude staff. Our luggage didn’t arrive

We did not know about the bag fees until check in. They are way too high. It’s insane. We also had a huge delay and everything costed extra which was very annoying.

Everything you need to know for your flight from Chicago to Santiago

Information on your arrival and departure airports