CHI - SCL

$240 Find Cheap Flights from Chicago to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Chicago to Santiago departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to Santiago.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to Santiago.
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Everything you should know

Cheapest round-trip
$506
Overall average: $785
Copa Airlines
Mon 3/30Sun 4/12
ORD - SCL • 1 stop
Cheapest one-way
$240
Typical prices: $386-$607
Copa Airlines
Tue 3/24
ORD - SCL • 1 stop
Top airlines
Copa Airlines
Cheapest • from $506 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Chicago and Santiago. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Montreal (YUL)
Cheapest • Avg $764 (round-trip)
Miami (MIA)
Shortest trip • 12h 40m (one-way)
Insights
Insights
Insights
Insights
When to book
4 weeks
in advance
Our data shows that travelers who book at least 4 weeks in advance save around 22% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
September
Cheapest • 18% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Chicago to Santiago (CHI-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Chicago to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Chicago to Santiago

Mon, Mar 30 - Sun, Apr 12
Copa Airlines Logo
7:56 am - 12:34 am
ORD
-
SCL
14h 38m
1 stop
Copa Airlines Logo
2:30 am - 1:13 am
SCL
-
ORD
23h 43m
1 stop
$506Copa Airlines
Wed, May 13 - Wed, May 27
Avianca Logo
11:20 pm - 2:15 pm
ORD
-
SCL
13h 55m
1 stop
Avianca Logo
6:40 am - 9:20 pm
SCL
-
ORD
15h 40m
1 stop
$511Avianca
Tue, Mar 10 - Tue, Mar 17
American Airlines Logo
6:10 am - 7:00 am
ORD
-
SCL
22h 50m
1 stop
American Airlines Logo
9:20 pm - 6:28 pm
SCL
-
ORD
23h 08m
1 stop
$525American Airlines
Tue, Mar 10 - Tue, Mar 17
American Airlines Logo
3:16 pm - 9:05 am
ORD
-
SCL
15h 49m
2 stops
American Airlines Logo
9:20 pm - 1:34 pm
SCL
-
ORD
18h 14m
2 stops
$530American Airlines
Tue, Apr 7 - Tue, Apr 14
LATAM Airlines Logo
10:45 am - 5:35 am
MDW
-
SCL
17h 50m
2 stops
LATAM Airlines Logo
7:55 pm - 12:07 pm
SCL
-
MDW
17h 12m
2 stops
$662LATAM Airlines
Mon, Aug 24 - Wed, Sep 23
Delta Logo
10:35 am - 7:15 am
MDW
-
SCL
19h 40m
1 stop
Delta Logo
8:40 pm - 4:27 pm
SCL
-
MDW
21h 47m
1 stop
$671Delta
Wed, Mar 18 - Tue, Mar 24
Multiple Airlines Logo
12:47 pm - 7:40 am
MDW
-
SCL
16h 53m
1 stop
Multiple Airlines Logo
9:05 pm - 5:48 pm
SCL
-
MDW
22h 43m
2 stops
$675Multiple Airlines
Mon, Mar 30 - Mon, Apr 13
Delta Logo
10:45 am - 8:15 am
MDW
-
SCL
19h 30m
1 stop
Delta Logo
11:00 pm - 4:29 pm
SCL
-
MDW
18h 29m
2 stops
$676Delta
Wed, May 6 - Wed, May 27
LATAM Airlines Logo
12:52 pm - 7:15 am
MDW
-
SCL
17h 23m
1 stop
LATAM Airlines Logo
8:40 pm - 10:00 am
SCL
-
MDW
14h 20m
1 stop
$702LATAM Airlines
Wed, Mar 18 - Tue, Mar 24
Multiple Airlines Logo
12:47 pm - 7:40 am
MDW
-
SCL
16h 53m
1 stop
Multiple Airlines Logo
11:25 pm - 5:48 pm
SCL
-
MDW
20h 23m
1 stop
$703Multiple Airlines
Booking Insights

KAYAK's insights & trends for Chicago to Santiago flights

Get data-powered insights and trends into flights from Chicago to Santiago to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Chicago to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago to Santiago is September, where tickets cost $659 (return) on average. On the other hand, the most expensive months are December and July, where the average cost of round-trip tickets is $940 and $882 respectively.

How far in advance should I book a flight from Chicago to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Chicago to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Chicago to Santiago, you should book around 4 weeks before departure, which saves you about 22% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 6 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$240
Best time to beat the crowds with an average 19% drop in price.
Most popular time to fly with an average 16% increase in price.
Flight from Chicago O'Hare Airport to Santiago

When to book flights from Chicago to Santiago

Are your dates flexible? Find out the best times to travel from Chicago to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Chicago to Santiago

  • Which airlines from Chicago to Santiago have the Unaccompanied Minor service?

    American Airlines provides an Unaccompanied Minor (UM) service for kids flying alone on flights from Chicago to Santiago. Children between the ages of 5 and 14 can use the service. Parents must fill out the relevant documentation, sign the Unaccompanied Minor form, and produce a legitimate form of identification. American Airlines ensures that minors traveling alone are monitored by devoted staff members from check-in to arrival at their destination.

  • Which airlines are suitable for families flying from Chicago to Santiago?

    American Airlines is a great option for family flights between Chicago and Santiago. Families traveling with youngsters can take advantage of American Airlines' perks, including priority boarding for those with strollers, complimentary meals for kids, and kid-friendly in-flight entertainment. Additionally, their airport lounges provide aid with stroller storage and feature family-friendly facilities like dedicated family rooms equipped with comfortable seating, televisions, and toys for kids to play with.

  • What is the most sustainable airline from Chicago to Santiago?

    When flying from Chicago to Santiago, Delta is one of the sustainable airlines to consider. In addition to investing in fuel-efficient aircraft, Delta has started carbon offset programs and waste reduction initiatives. Additionally, they participate in research projects on biofuels that aim to create and utilize environmentally friendly jet fuel. Delta has also committed to lowering the usage of single-use plastics and actively recycling waste generated while traveling.

  • Which airlines offer business- and first-class flights from Chicago to Santiago?

    American Airlines and LATAM Airlines provide first- and business-class services from Chicago to Santiago. American Airlines' business-class service offers lie-flat seats, premium dining options, access to their Admirals Club lounges, priority boarding, and dedicated customer service. LATAM offers entirely flat beds, priority check-in and boarding, access to VIP lounges, great cuisine, and a large range of wines and spirits as part of their business-class service.

  • What is the cheapest flight from Chicago to Santiago?

    In the last 3 days, the lowest price for a flight from Chicago to Santiago was $240 for a one-way ticket and $506 for a round-trip.

  • Do I need a passport to fly between Chicago and Santiago?

    Yes, you’ll need a passport to travel to Santiago from Chicago.

  • Which airports will I be using when flying from Chicago to Santiago?

    Chicago is served by 2 major airports and there is only 1 main airport in Santiago. You will leave Chicago from one of these airports: Chicago Midway or Chicago O'Hare Intl. You will be arriving at Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Chicago to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Chicago to Santiago?

    SkyTeam, oneworld, and Star Alliance are the airline alliances operating flights between Chicago and Santiago, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Chicago to Santiago, Delta or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Chicago to Santiago are Delta and LATAM Airlines. With an average price for the route of $883 and an overall rating of 7.9, Delta is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $819 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Chicago to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Chicago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Chicago with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Chicago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Chicago to Santiago

  • Passengers looking to visit downtown from Santiago Airport (SCL) can use several buses available at the airport. The Centro Puerto bus leaves Santiago Airport every 30 minutes to downtown. Metro de Santiago bus line 5 runs every 5 minutes from SCL to Santa Ana.
  • Passengers with limited mobility should consider flying with United from Chicago to Santiago. United Airlines offers assistance with boarding and deplaning, wheelchair service, and priority seating. The airline also provides accessible restrooms and the choice of purchasing an Economy Plus seat for more legroom for passengers with limited mobility.
  • Flights from Chicago to Santiago will land at Comodoro Arturo Merino Benítez International Airport (SCL). SCL is a hub for LATAM Airlines, providing passengers with more frequent flight options and easier connections to other cities.
  • Flights from Chicago to Santiago include at least a single layover en route. Most layover cities depend on the airline and departing airport. Delta, United, American Airlines, LATAM Airlines, and Spirit Airlines offer most of the flights on these routes, and the most common layovers are in Dallas, New York, Miami, and Panama cities.
  • LATAM Airlines has one of the most favorable pet policies for flights from Chicago to Santiago. Pets traveling in-cabin must be in a ventilated, leak-proof kennel with enough space for the pet. The kennel and the pet combined should weigh at most 18 lb, and the dimensions should be at most 15.5 x 11.5 x 8.5 inches.

Reviews of the top 5 airlines serving from Chicago to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Chicago to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Chicago to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8238 reviews
8.1Boarding
7.9Comfort
8.5Crew
7.2Food
7.8Entertainment
Airline reviews

The staff was fine. The plane was extremely tight, and I paid for the wifi and it did not work at all. I was actually going to ask for a refund.

4.0 OkayNicole, Feb 2026
SDF - LGA
Read more Delta reviews

The staff was fine. The plane was extremely tight, and I paid for the wifi and it did not work at all. I was actually going to ask for a refund.

two hour delay and the Delta representative on the PA system was unable to understand

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

2+hrs delay without any reason provided and a cramped flight

We waited an hour on the runway to get a gate in Orlando

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

Flight was delayed due to crew being not on time

Flight crew issues delayed my flight by 2 1/2 hours. Causing me to miss my connection.

The staff on board and gate was nice - a welcome change from the usual. We also arrived early, which was a great benefit, given that it takes 30 minutes plus to get bags at SRQ.

The staff was frielndly. The plane was terrible, it was too small and should be decommissioned. There were no back seat screens at all. The only beverages we had a choice from was coffee, tea or water. The only bathroom in the back was behind the flight attendant's jump seat and wasn't working. And I literally felt like I was sitting on top of the guy next to me. It was terribly hot in the plane and we had to sit on the tarmac in Chicago for 1/2 hour due to congestion in Mpls. Wouldn't they have know that before they even boarded us so that we could have sat in comfort in the terminal?

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

We were delayed for about an hour from taking off due to traffic control procedures at the destination airport. But once in the air, the flight went well. The crew members were great and provided cabin service despite moderate turbulence during much of the flight.

Short flight, but no drink/snack service. The flights both going and coming were delayed.

Not being stranded in Chicago for her airport to 11:30 tomorrow morning the 3rd

I was fully checked in the prior night and i was unchecked and then didn’t have a seat when I boarded. Instead of an aisle seat, I was out in the middle seat of the very last row of the plane.

In overall it was a good experience, the only down point was that the entertainment screen was working properly.

They lost my luggage, so, not happy. The crew was nice but my suitcases never made it, still trying to find out what happened!

I understand weather is an issue, but making us chase our plane down at five scheduled gates across three terminals in an airport the size of O'Hare was unfair. They'd have probably been better off to leave gates as TBD until the inbound plane is in final approach instead of running us all over the place. Also, props to the consistently-unprepared ground crew in Richmond for once again leaving my lane parked short of the gate because they couldn't have a crew in place on time with 2 hours notice...

cabin crew was OK, food was OK, the trip from the US to Munich was actually pretty bad comfort wise. Noisy aircraft, lights never dimmed even in Business class (night flight) barely sufficient amenities for the price. I have millions of miles with United but TBH American is gaining ground and Delta has always been marginally better then United although on paper United has more longes and cheaper upgrades.

Essy to get on. The hostess gave very little pop, the plane was late getting in, and we are still waiting for our bags. This sucks. :/

Not United Airlines' fault. It's ORL airport's fault.

Flight to Tampa was delayed taking off due to plane arriving late but no other issues

As previously stated the delay I experienced flying from Wichita to Chicago caused a host of issues. When I finally was able to be booked on the last remaining American flight from Chicago to Cincinnati, the gate changed four times with the last change occurring very near the scheduled boarding time. While I didn't have a problem moving from gate to gate, I did notice and make note of others that had mobility issues and had to move each time for the gate change.

Maintenance took a very long time and then we were in a holding pattern. While a one-off maintenance issue is standard, there were delays on both of my flights for this trip based on maintenance issues with the planes, which delayed both flights over 45 minutes. Thankfully, I didn't have any connections but it wasn't an experience that would make me pick AA if I have other options.

No Snacks or Entertainment. The flight was short, snacks should still be given.

See prior comment about how Kayak mishandled my reservation and delayed my arrival by 6 hours.

Boarding delayed 20 minutes for no reason, no wifi, in flight entertainment, or snacks / waters?

Delayed an hour due to operational issues. Minimal apologies or care for the significant inconvenience caused. Landed at nearly 1am and they still couldn’t find ground staff to get us off the plane promptly.

The aircraft had several problems - from excess fuel to non operational ac. Two hours of delay in Chicago could have been avoided with proper planning and aircraft maintenance.

Crew in Columbia was not prepared for landing. It was a bit of a disaster and getting bags took forever.

We were upgraded to First Class and it was a great flight

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

The flight attendant smashed her beverage cart into my knee, causing significant amount of pain. The seats were extremely uncomfortable. No food or drink is offered unless you want to pay the ridiculous prices for it. The schedule of flying in the overnight hours is also very uncomfortable.

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

I like the crew they're very friendly. I don't like. on five hour flight they not offered snacks. Any drink. Not even coffee

Everything you need to know for your flight from Chicago to Santiago

Information on your arrival and departure airports