$65 Find Cheap Flights from Chicago Midway Airport to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Midway to South Carolina departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
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Cheap Flights from Midway to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$293
Myrtle Beach
Myrtle Beach2 stops$231
Greenville
Greenville1 stop$215
Columbia
Columbia1 stop$185
Charlotte
Charlottenonstop$129
Charleston
Charleston1 stop$293
Myrtle Beach
Myrtle Beach2 stops$231
Greenville
Greenville1 stop$215
Columbia
Columbia1 stop$185
Charlotte
Charlottenonstop$129

Book Cheap Midway to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Midway to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Midway to South Carolina

Mon, Feb 2 - Mon, Feb 9
Southwest Logo
1:30 pm - 4:20 pm
MDW
-
CLT
1h 50mnonstop
Southwest Logo
5:50 am - 6:55 am
CLT
-
MDW
2h 05mnonstop
$129Southwest
Tue, Jan 20 - Tue, Jan 20
Southwest Logo
1:30 pm - 4:20 pm
MDW
-
CLT
1h 50mnonstop
Southwest Logo
5:50 pm - 6:55 pm
CLT
-
MDW
2h 05mnonstop
$139Southwest
Tue, Feb 24 - Wed, Feb 25
Southwest Logo
6:10 am - 12:40 pm
MDW
-
CLT
5h 30m2 stops
Southwest Logo
5:50 pm - 6:55 pm
CLT
-
MDW
2h 05mnonstop
$144Southwest
Mon, Feb 2 - Thu, Feb 5
Frontier Logo
1:00 pm - 10:40 am
MDW
-
CLT
20h 40m1 stop
Frontier Logo
6:54 pm - 7:52 pm
CLT
-
MDW
25h 58m1 stop
$145Frontier
Wed, Feb 11 - Mon, Feb 16
Southwest Logo
1:30 pm - 4:20 pm
MDW
-
CLT
1h 50mnonstop
Southwest Logo
5:35 am - 6:35 am
CLT
-
MDW
2h 00mnonstop
$146Southwest
Thu, Apr 9 - Mon, Apr 13
Frontier Logo
8:00 am - 7:38 pm
MDW
-
CLT
10h 38m1 stop
Frontier Logo
8:52 am - 9:58 pm
CLT
-
MDW
14h 06m1 stop
$151Frontier
Mon, Mar 30 - Wed, Apr 8
Delta Logo
12:47 pm - 6:55 pm
MDW
-
AGS
5h 08m1 stop
Delta Logo
1:00 pm - 5:54 pm
AGS
-
MDW
5h 54m1 stop
$185Delta
Mon, Mar 30 - Mon, Apr 13
Delta Logo
12:47 pm - 7:58 pm
MDW
-
CAE
6h 11m1 stop
Delta Logo
7:15 pm - 10:29 pm
CAE
-
MDW
4h 14m1 stop
$185Delta
Mon, Feb 9 - Fri, Feb 13
Multiple Airlines Logo
7:00 pm - 2:42 pm
MDW
-
MYR
18h 42m2 stops
Multiple Airlines Logo
3:20 pm - 2:55 pm
MYR
-
MDW
24h 35m1 stop
$231Multiple Airlines
Thu, Feb 19 - Thu, Feb 26
Multiple Airlines Logo
12:22 pm - 8:13 am
MDW
-
MYR
18h 51m2 stops
Multiple Airlines Logo
10:30 am - 2:26 pm
MYR
-
MDW
28h 56m1 stop
$242Multiple Airlines
Booking Insights

KAYAK's insights & trends for Midway to South Carolina flights

Get data-powered insights and trends into flights from Midway to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Chicago Midway Airport to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Chicago Midway Airport found in the last 72 hours was to Myrtle Beach, at $304 round-trip. The most popular route is from Chicago Midway Airport (MDW) to Myrtle Beach (MYR), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $304.

Can I save money by flying with a layover from Chicago Midway Airport to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $376 on average.

What’s the cheapest day of the week to fly from Chicago Midway Airport to South Carolina?

The average price of all round-trip flights from Chicago Midway Airport to South Carolina clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to South Carolina on a Tuesday and more expensive on a Thursday. On your return trip to Chicago Midway Airport, you should consider flying back on a Wednesday, and avoid Sundays for better deals.

Good to know

Low seasonJanuary
Cheapest flight$65
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly with an average 12% increase in price.
Flight from Chicago Midway Airport to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Chicago Midway Airport to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago Midway Airport to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago Midway Airport to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Chicago Midway Airport to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago Midway Airport to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Chicago Midway Airport to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago Midway Airport to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Chicago Midway Airport to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally in the afternoon, when round-trip flights cost $349 on average. Morning departures are around 4% more expensive than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the morning, which is peak travel time and where the average cost of a ticket is $383.

Reviews of the top airlines flying from Midway to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Chicago to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Midway to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4250 reviews
7.0Food
8.6Crew
8.1Boarding
8.0Comfort
7.5Entertainment
Airline reviews

The flight crew was extremely rude and especially not helpful when our flight was delayed.

2.0 MediocreMatthew, Jan 2026
DAL - SAN
Read more Southwest reviews

The flight crew was extremely rude and especially not helpful when our flight was delayed.

Pretty seamless, just a tad bit late in taking off and landing.

Flight was fine other than there was a gate change that I was not notified of. By chance I happened to check my phone and saw the change, otherwise, we would have missed our connecting flight.

Haven’t flown on SW in years. Flight was on time departing and arriving. Served vegan butter onion flavored pretzels which were bad. Coke served was in a tiny paper cup. Crew was not engaging. Felt like they were going through the motions. Old plane, tight seats and no leg room.

Check-in, Boarding and flight were smooth. All the employees and crew was very nice and funny. They gave the kids crayons and workbooks to keep them occupied which was a big win. I’ve flown Southwest many times and that’s the first time I’ve seen that and it is a great addition.

Flight was on time. Wi-fi was a little spotty/slow. Boarding and exit were efficient.

Okay, not wonderful. Short flight. Wi-fi didn't work properly. Stuck waiting for a gate to open upon arrival for 20 or so minutes.

They sent a notice that they were boarding an hour early. We had to leave the club and run to the gate. They said sorry, that came from corporate and was a mistake. They did not have enough seating because the flight before it had not taken off on time. They moved our gate and delayed it for an hour.

The boarding and seat assignment system no longer works for me, but I know it is being replaced. Otherwise, I am good with the overall experience.

The lead steward kept singing about "San Francisco" and hotel California---more annoying than humorous....needs work. Flight was smooth and on time.

It was Delta, but the flight attendants were stressful and disrespectful. I am a diamond member a travel weekly. I have not had a negative thing to share in quite some time. But this was noticeable.

Comfort Plus seat 11E seemed smaller than prior flights. The movie selection is good. Watched most of the most recent Tron movie. I'll watch the remaining part later as my movie is saved in the Delta Seatback Experience.

Flight was late from Newark to Atlanta, I asked flight attendant to please let my family of 3 out first when we landed to Atlanta because we were late for our connecting flight to Quito. She didn't and we were late for 5 minutes we couldn't board the plane and spend hours trying to get another flight with customer service for the next day.

I really liked the legroom. I am 6’4”.a at For some reason our seats were not together and using the app to fix it didn’t work. Passengers were nice enough to move for us but you should absolutely ensure a parent sits with their child.

Late delayed flight delays boarding and delays leaving and delays on arrival too. Cramped plane no room no food.

DTW line is too long. The flights from DTW to BWI are always delayed for unknown reasons.

Delta canceled our flight and we had to scramble to find another airline to get home. Phoenix is not a delta hub so they didn’t have another plane. It would have been a red eye though Salt Lake City. Getting in at 5am. No bueno.

This flight was no comparison to our prior flight. I'm thinking it all has to do with the age of the aircraft.

This flight was a first class choice and left much to be desired. Seat backs on seats were falling apart and torn. Seats actually didn't come to a "full & upright position". Pull out table was sprung. Not any significant leg room. All in all we were on an obviously older plane and felt overcharged for what we received as first class.

Flight was delayed several times. At one point, they "pulled back" 15 minutes from the delayed boarding and sent a text saying we would board sooner than previously advised. The flight then was delayed again. And when we boarded, there was an unspecified technical issue which had us waiting in the plane for about an hour.

Everything you need to know for your flight from Midway to South Carolina

Information on your arrival and departure airports