$65 Find Cheap Flights from Chicago Midway Airport to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Midway to South Carolina departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Midway to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston2 stops$287
Myrtle Beach
Myrtle Beach2 stops$281
Greenville
Greenville1 stop$213
Columbia
Columbia1 stop$249
Charlotte
Charlotte1 stop$159
Charleston
Charleston2 stops$287
Myrtle Beach
Myrtle Beach2 stops$281
Greenville
Greenville1 stop$213
Columbia
Columbia1 stop$249
Charlotte
Charlotte1 stop$159

Book Cheap Midway to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Midway to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Midway to South Carolina

Tue, Apr 14 - Mon, Apr 20
Multiple Airlines Logo
7:30 am - 1:52 pm
MDW
-
CLT
5h 22m
1 stop
Multiple Airlines Logo
5:30 pm - 1:00 pm
CLT
-
MDW
20h 30m
1 stop
$159Multiple Airlines
Sun, Apr 26 - Wed, Apr 29
Frontier Logo
2:00 pm - 9:27 am
MDW
-
CLT
18h 27m
1 stop
Frontier Logo
8:09 pm - 7:21 am
CLT
-
MDW
12h 12m
1 stop
$160Frontier
Mon, Apr 13 - Thu, Apr 16
Frontier Logo
5:30 am - 12:36 am
MDW
-
CLT
18h 06m
1 stop
Frontier Logo
4:42 pm - 10:22 pm
CLT
-
MDW
6h 40m
1 stop
$167Frontier
Sun, Apr 26 - Wed, Apr 29
Frontier Logo
2:00 pm - 9:27 am
MDW
-
CLT
18h 27m
1 stop
Frontier Logo
8:09 pm - 7:21 am
CLT
-
MDW
12h 12m
1 stop
$171Frontier
Fri, May 8 - Thu, May 14
Frontier Logo
9:14 am - 4:35 pm
MDW
-
CLT
6h 21m
1 stop
Frontier Logo
3:30 pm - 8:04 am
CLT
-
MDW
17h 34m
1 stop
$181Frontier
Sat, Apr 18 - Mon, Apr 20
Multiple Airlines Logo
9:14 am - 5:47 pm
MDW
-
CLT
7h 33m
1 stop
Multiple Airlines Logo
10:16 am - 1:00 pm
CLT
-
MDW
27h 44m
1 stop
$185Multiple Airlines
Fri, Aug 21 - Sun, Aug 23
Delta Logo
1:05 pm - 8:16 pm
MDW
-
GSP
6h 11m
1 stop
Delta Logo
5:45 am - 9:50 am
GSP
-
MDW
5h 05m
1 stop
$213Delta
Fri, Jul 17 - Sun, Jul 19
Delta Logo
10:35 am - 4:13 pm
MDW
-
GSP
4h 38m
1 stop
Delta Logo
6:45 am - 11:56 am
GSP
-
MDW
6h 11m
1 stop
$233Delta
Thu, Apr 2 - Tue, Apr 7
Southwest Logo
5:25 am - 11:45 am
MDW
-
GSP
5h 20m
1 stop
Southwest Logo
5:05 pm - 8:00 pm
GSP
-
MDW
3h 55m
1 stop
$239Southwest
Fri, Apr 3 - Mon, Apr 6
Southwest Logo
6:25 pm - 10:45 pm
MDW
-
GSP
3h 20m
1 stop
Southwest Logo
6:25 pm - 12:05 am
GSP
-
MDW
6h 40m
1 stop
$244Southwest
Booking Insights

KAYAK's insights & trends for Midway to South Carolina flights

Get data-powered insights and trends into flights from Midway to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Chicago Midway Airport to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Chicago Midway Airport found in the last 72 hours was to Charleston, at $270 round-trip. The most popular route is from Chicago Midway Airport (MDW) to Myrtle Beach (MYR), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $368.

What is the cheapest time of day to fly to South Carolina?

The average price for all round-trip flights from Chicago Midway Airport to South Carolina depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to South Carolina is generally in the afternoon, when round-trip flights cost $341 on average. Morning departures are around 2% more expensive than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the morning, which is peak travel time and where the average cost of a ticket is $367.

Can I save money by flying with a layover from Chicago Midway Airport to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 2 stops layover the cheapest option at $429 on average.

What’s the cheapest day of the week to fly from Chicago Midway Airport to South Carolina?

The average price of all round-trip flights from Chicago Midway Airport to South Carolina clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to South Carolina on a Tuesday and more expensive on a Thursday. On your return trip to Chicago Midway Airport, you should consider flying back on a Wednesday, and avoid Sundays for better deals.

Good to know

Low seasonJanuary
Cheapest flight$65
Best time to beat the crowds with an average 24% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Chicago Midway Airport to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Chicago Midway Airport to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago Midway Airport to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago Midway Airport to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Chicago Midway Airport to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago Midway Airport to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Chicago Midway Airport to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago Midway Airport to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Chicago Midway Airport to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Midway to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Chicago to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Midway to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4317 reviews
7.0Food
8.1Boarding
8.0Comfort
8.6Crew
7.5Entertainment
Airline reviews

Long layover between flights to Long Island from BWI - need better coordination between flights

4.0 OkayKenny, Mar 2026
TPA - BWI
Read more Southwest reviews

Long layover between flights to Long Island from BWI - need better coordination between flights

I elected to pay for the upgrades and found very little difference

The new seating arrangement is so over priced for what you get.

The problem with the seat assignments is that there were a lot of rows in the front that were empty but my row at the back was full. Just not so pleasant.

No food or entertainment, just a quick 40 minute flight. A little bumpy due to Santa Ana winds but pilot has no control over that. Good flight and landing!

Good but I prefer choose your own seat. With the new assigned seats they should board from the back I see no advantage to this new boarding. Just like every other airline

I realize they are still working out kinks with the new boarding process, but by the time I boarded in group 5, most of the bins were full. All airlines should better enforce small bags and jackets going under the seats until everyone has boarded.

WiFi was not working and didn’t have a beverage service

Snacks are always pretzels. Why can't you also offer peanuts ?

Flight boarded late after announcing on time boarding. Flight arrived only a little late despite late departure. Had trouble connecting to WiFi

Love delta smaller commuter plane so no entertainment and paid wifi on MKE-LGA leg was extremely unreliable and slow

Stop changing gates. Stop cancelling flights Stop moving my seat.

Extremely disappointed with Delta. They canceled flight last minute and then I rebooked the other flights and with which were delayed as well

Could not get my connecting flight boarding pass until four hrs before departure! Ver annoying especially since the staff could not explain why!

The flight was flying with 30% capacity. The flight my seat from preferred seating to back of the seat. Even though i can understand that this was to balance the flight weight. The flight attendance decided to do the serving near my seat and in the middle , their noices woke me up from sleep , when i realized that the service has ended and when they were going back asked for a coffee, for which they answered they have completed teh service in my location. That really upset me as they woke me up and also rejected the coffee i asked. I ended up landing with a headache, thanks to the crew that screwed up my travel

Delayed. Hot. Passenger next to me was so large I couldn’t move.

Same experience as the flight from Norfolk to Atlanta where people are boarded in zones that don't make sense. People behind you on the plane will get on before you and they take the luggage space on your row.

The boarding process doesn't make sense since some people that will sit behind your rows are boarded before you and then they take up the luggage space above your head. I then have to wait for people to get off the plane before I can go back to get my luggage.

Good flight. Connector flight was delayed so made a short turnaround in Atlanta which was stressful. Otherwise, great crew, Staff in ATL was very informative about the delay and ensured people their connections were fine. Notified the ones that were not. Great communication.

The flight went very well, but the flight attendants didn't serve and food or drinks other than 1st class due to rough air but to be honest it wasn't that bumpy and I felt that they could've at least offered water and coffee perhaps. Also serving 1st class only is a bad look. I've been in 1st class many times and I would've felt that if the turbulence was too rough for the main cabin, it would be too rough for 1st class too.

Everything you need to know for your flight from Midway to South Carolina

Information on your arrival and departure airports