$70 Find Cheap Flights from Chicago Midway Airport to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Midway to South Carolina departing on 4/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Midway to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$285
Myrtle Beach
Myrtle Beach1 stop$272
Greenville
Greenville1 stop$269
Columbia
Columbia1 stop$289
Charlotte
Charlotte1 stop$180
Charleston
Charleston1 stop$285
Myrtle Beach
Myrtle Beach1 stop$272
Greenville
Greenville1 stop$269
Columbia
Columbia1 stop$289
Charlotte
Charlotte1 stop$180

Book Cheap Midway to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Midway to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Midway to South Carolina

Fri, Apr 17 - Sat, Apr 18
Frontier Logo
9:14 am - 4:30 pm
MDW
-
CLT
6h 16m
1 stop
Frontier Logo
8:09 pm - 7:59 am
CLT
-
MDW
12h 50m
1 stop
$180Frontier
Wed, Apr 15 - Wed, Apr 22
Frontier Logo
7:30 am - 7:14 pm
MDW
-
CLT
10h 44m
1 stop
Frontier Logo
8:09 pm - 7:26 am
CLT
-
MDW
12h 17m
1 stop
$183Frontier
Tue, Apr 14 - Thu, Apr 16
Multiple Airlines Logo
7:30 am - 5:34 pm
MDW
-
CLT
9h 04m
1 stop
Multiple Airlines Logo
8:56 am - 7:31 pm
CLT
-
MDW
11h 35m
2 stops
$185Multiple Airlines
Mon, Apr 13 - Mon, Apr 20
Delta Logo
5:21 pm - 11:58 pm
MDW
-
AGS
5h 37m
1 stop
Delta Logo
6:17 pm - 10:28 pm
AGS
-
MDW
5h 11m
1 stop
$187Delta
Wed, Apr 22 - Tue, Apr 28
Multiple Airlines Logo
7:30 am - 7:14 pm
MDW
-
CLT
10h 44m
1 stop
Multiple Airlines Logo
11:17 am - 7:31 pm
CLT
-
MDW
9h 14m
2 stops
$191Multiple Airlines
Tue, Apr 28 - Wed, Apr 29
Multiple Airlines Logo
7:30 am - 11:08 pm
MDW
-
CLT
14h 38m
1 stop
Multiple Airlines Logo
9:32 pm - 7:21 am
CLT
-
MDW
10h 49m
1 stop
$194Multiple Airlines
Wed, Apr 29 - Wed, May 6
Multiple Airlines Logo
7:30 am - 11:08 pm
MDW
-
CLT
14h 38m
1 stop
Multiple Airlines Logo
10:57 am - 10:02 pm
CLT
-
MDW
12h 05m
2 stops
$195Multiple Airlines
Sat, Apr 18 - Tue, Apr 21
Southwest Logo
2:15 pm - 8:40 pm
MDW
-
GSP
5h 25m
1 stop
Southwest Logo
5:05 pm - 10:15 pm
GSP
-
MDW
6h 10m
1 stop
$269Southwest
Sat, Apr 18 - Tue, Apr 21
Southwest Logo
4:20 pm - 8:40 pm
MDW
-
GSP
3h 20m
1 stop
Southwest Logo
1:55 pm - 7:30 pm
GSP
-
MDW
6h 35m
1 stop
$272Southwest
Wed, Apr 8 - Sat, Apr 11
Delta Logo
6:00 am - 1:21 pm
MDW
-
CHS
6h 21m
1 stop
Delta Logo
5:27 am - 9:56 am
CHS
-
MDW
5h 29m
1 stop
$285Delta
Booking Insights

KAYAK's insights & trends for Midway to South Carolina flights

Get data-powered insights and trends into flights from Midway to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Chicago Midway Airport to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Chicago Midway Airport found in the last 72 hours was to Charleston, at $270 round-trip. The most popular route is from Chicago Midway Airport (MDW) to Myrtle Beach (MYR), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $331.

What is the cheapest time of day to fly to South Carolina?

The average price for all round-trip flights from Chicago Midway Airport to South Carolina depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to South Carolina is generally in the afternoon, when round-trip flights cost $355 on average. Morning departures are around 8% cheaper than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the evening, which is peak travel time and where the average cost of a ticket is $399.

Can I save money by flying with a layover from Chicago Midway Airport to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 2 stops layover the cheapest option at $429 on average.

What’s the cheapest day of the week to fly from Chicago Midway Airport to South Carolina?

The average price of all round-trip flights from Chicago Midway Airport to South Carolina clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to South Carolina on a Tuesday and more expensive on a Thursday. On your return trip to Chicago Midway Airport, you should consider flying back on a Thursday, and avoid Sundays for better deals.

Good to know

Low seasonJanuary
Cheapest flight$70
Best time to beat the crowds with an average 24% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Chicago Midway Airport to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Chicago Midway Airport to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago Midway Airport to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago Midway Airport to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Chicago Midway Airport to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago Midway Airport to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Chicago Midway Airport to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago Midway Airport to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Chicago Midway Airport to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Midway to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Chicago to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Midway to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4320 reviews
8.6Crew
7.5Entertainment
7.0Food
8.1Boarding
8.0Comfort
Airline reviews

I flew twice this week on Southwest, was delayed over 2 hours both ways. From Pittsburgh to Chicago it was due to weather but the gate agents, pilot etc were great at updating everyone. Today from Midway to Pittsburgh the plane had come from an international location, kept getting delayed, no information was given until we were delayed for the third time. It was ridiculous, whoever scheduled that plane to fly to Pittsburgh after didn’t consider a lot of things.

2.0 MediocreBeth, Mar 2026
MDW - PIT
Read more Southwest reviews

I flew twice this week on Southwest, was delayed over 2 hours both ways. From Pittsburgh to Chicago it was due to weather but the gate agents, pilot etc were great at updating everyone. Today from Midway to Pittsburgh the plane had come from an international location, kept getting delayed, no information was given until we were delayed for the third time. It was ridiculous, whoever scheduled that plane to fly to Pittsburgh after didn’t consider a lot of things.

Boarding was easy. The seats are small and fairly uncomfortable

I was supposed to be on a later flight. When I showed up at the gate, the woman working there was extremely helpful getting moved up to this earlier flight.

We had a 5 hour delay on the tarmac in Baltimore

Long layover between flights to Long Island from BWI - need better coordination between flights

I elected to pay for the upgrades and found very little difference

The new seating arrangement is so over priced for what you get.

The problem with the seat assignments is that there were a lot of rows in the front that were empty but my row at the back was full. Just not so pleasant.

No food or entertainment, just a quick 40 minute flight. A little bumpy due to Santa Ana winds but pilot has no control over that. Good flight and landing!

Good but I prefer choose your own seat. With the new assigned seats they should board from the back I see no advantage to this new boarding. Just like every other airline

I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.

NEVER MADE THE FLIGHT BECAUSE DELTA SAID THEY CAN NOT

THEY FAILED ME AND I NEVER GOT ON THE FLIGHT BECAUSE IT WAS SO DELAYED! I ENDED UP HAVING TO PAY OUT OF POCKET FOR A HOTEL AND STAY IN NASHVILLE TO CATCH A FLIGHT FOR THE FOLLOWING DAY. DELTA IS POOR CUSTOMER SERVICE>

8 hours late and the plane smelled like urine, that smell in the morning when your child wet the bed in the night.

My flight was canceled on Sunday. Rebooking took three hours. Had to pay for accommodations another night. New flight was delayed for 5 hours, all that was sent was a 12 dollar food voucher, which doesn’t tell you how to use it. Then when we landed we had to sit on the plane for an hour before we could get off.

Miserable. This entire round trip was miserable. I booked evening flights to and from Detroit on consecutive days that should have had me at my destination by 10:30. Instead I arrived after 3am on my flight to Detroit and after midnight on my return. Multiple unforced errors like awaiting bags to get put on the plane for almost an hour in Detroit and a 20 minute delay to pull up to the gate in Atlanta has me rethinking my assumption that delta is the best and most reliable airline

Perhaps when you’re sitting in 1st class and the crew closes the bathroom for the pilots, there could be a notification other than holding your hands up as a blockade when you get there and you’re told the restrooms are closed please turn around … especially at night when visibility is poor and you’re met by a flight attendants with their arms up

First class is comfortable. Enjoyed a movie and was able to relax compared to coach.

Loved flying First Class. Very comfortable. The seat was amazing. Enjoyed a movie and was able to relax so much better than in coach.

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

Everything you need to know for your flight from Midway to South Carolina

Information on your arrival and departure airports