$70 Find Cheap Flights from Chicago Midway Airport to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Midway to South Carolina departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Midway to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$278
Myrtle Beach
Myrtle Beach1 stop$238
Greenville
Greenville1 stop$222
Columbia
Columbia1 stop$229
Charlotte
Charlottenonstop$139
Charleston
Charleston1 stop$278
Myrtle Beach
Myrtle Beach1 stop$238
Greenville
Greenville1 stop$222
Columbia
Columbia1 stop$229
Charlotte
Charlottenonstop$139

Book Cheap Midway to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Midway to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Midway to South Carolina

Tue, Feb 24 - Sat, Feb 28
Southwest Logo
1:30 pm - 4:20 pm
MDW
-
CLT
1h 50mnonstop
Southwest Logo
6:25 pm - 7:30 pm
CLT
-
MDW
2h 05mnonstop
$139Southwest
Thu, Feb 19 - Sat, Feb 21
Frontier Logo
6:15 am - 5:50 pm
MDW
-
CLT
10h 35m
1 stop
Frontier Logo
9:28 am - 2:55 pm
CLT
-
MDW
6h 27m
1 stop
$144Frontier
Tue, Feb 17 - Tue, Feb 24
Southwest Logo
6:00 pm - 8:50 pm
MDW
-
CLT
1h 50mnonstop
Southwest Logo
5:50 pm - 6:55 pm
CLT
-
MDW
2h 05mnonstop
$149Southwest
Thu, Feb 26 - Wed, Mar 4
Frontier Logo
6:15 am - 5:50 pm
MDW
-
CLT
10h 35m
1 stop
Frontier Logo
2:46 pm - 2:26 pm
CLT
-
MDW
24h 40m
1 stop
$155Frontier
Sat, Feb 21 - Mon, Feb 23
Southwest Logo
2:30 pm - 5:20 pm
MDW
-
CLT
1h 50mnonstop
Southwest Logo
6:20 pm - 7:25 pm
CLT
-
MDW
2h 05mnonstop
$158Southwest
Tue, Feb 10 - Wed, Feb 18
Southwest Logo
1:30 pm - 4:20 pm
MDW
-
CLT
1h 50mnonstop
Southwest Logo
5:50 pm - 6:55 pm
CLT
-
MDW
2h 05mnonstop
$159Southwest
Mon, Feb 9 - Wed, Feb 11
Frontier Logo
7:00 pm - 1:51 pm
MDW
-
CLT
17h 51m
1 stop
Frontier Logo
2:46 pm - 2:26 pm
CLT
-
MDW
24h 40m
1 stop
$160Frontier
Thu, Feb 19 - Sun, Feb 22
Frontier Logo
6:15 am - 5:50 pm
MDW
-
CLT
10h 35m
1 stop
Frontier Logo
10:50 am - 1:08 pm
CLT
-
MDW
27h 18m
1 stop
$177Frontier
Sat, Feb 14 - Wed, Feb 25
Delta Logo
11:06 am - 4:04 pm
MDW
-
CLT
3h 58m
1 stop
Delta Logo
1:11 pm - 5:37 pm
CLT
-
MDW
5h 26m
1 stop
$178Delta
Thu, Feb 19 - Thu, Feb 26
Delta Logo
12:45 pm - 6:53 pm
MDW
-
AGS
5h 08m
1 stop
Delta Logo
7:38 pm - 10:31 pm
AGS
-
MDW
3h 53m
1 stop
$215Delta
Booking Insights

KAYAK's insights & trends for Midway to South Carolina flights

Get data-powered insights and trends into flights from Midway to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Chicago Midway Airport to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Chicago Midway Airport found in the last 72 hours was to Charleston, at $301 round-trip. The most popular route is from Chicago Midway Airport (MDW) to Myrtle Beach (MYR), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $327.

Can I save money by flying with a layover from Chicago Midway Airport to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $360 on average.

What’s the cheapest day of the week to fly from Chicago Midway Airport to South Carolina?

The average price of all round-trip flights from Chicago Midway Airport to South Carolina clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to South Carolina on a Tuesday and more expensive on a Thursday. On your return trip to Chicago Midway Airport, you should consider flying back on a Wednesday, and avoid Sundays for better deals.

Good to know

Low seasonJanuary
Cheapest flight$70
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly with an average 12% increase in price.
Flight from Chicago Midway Airport to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Chicago Midway Airport to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago Midway Airport to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago Midway Airport to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Chicago Midway Airport to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago Midway Airport to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Chicago Midway Airport to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago Midway Airport to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Chicago Midway Airport to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally in the afternoon, when round-trip flights cost $341 on average. Morning departures are around 4% more expensive than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the morning, which is peak travel time and where the average cost of a ticket is $383.

Reviews of the top airlines flying from Midway to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Chicago to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Midway to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4266 reviews
8.0Comfort
8.6Crew
8.1Boarding
7.0Food
7.5Entertainment
Airline reviews

Great flight but super high price. Glad it was a business trip and not personal

10.0 ExcellentPieter, Jan 2026
LGB - DAL
Read more Southwest reviews

Great flight but super high price. Glad it was a business trip and not personal

On time. Friendly staff. Took to long to pre bord all the specialty groups. Cramped small plane

The seats were comfortable, and the boarding process was pretty smooth.

3 hour delay. Had to change plans and was still delayed.

The staff was very friendly, professional, and courteous. The overall flight was a great experience.

The crew canceled the complementary snack and drink in anticipation of turbulence that never materialized. I was counting on the drink (water) to take the the doses of medication - prescribed for my heart condition - that were due during the flight. Since no snack or meal was served on this flight, I cannot rate the food quality. Otherwise, this flight was excellent.

Departure was delayed more than 1/2 hour while we waited for luggage (only) transfer from another flight/plane. Once approved for takeoff, the flight was excellent.

We got exit row seats both flights. Everything was running on time

The flight crew was extremely rude and especially not helpful when our flight was delayed.

Pretty seamless, just a tad bit late in taking off and landing.

There was no wifi available on this flight. And there were no screens, no onboard entertainment, no entertainment options at all. It was like travelling in the 1990s again, except without even a main screen for options. Seats, as usual, were tight and uncomfortable.

Good seat comfort ORF to ATL. Bad seat ATL to SEA (terrible lumbar support, hard, ouch)..

Because I was moved to an exit row, the snacks in economy comfort, the selection of snacks was better.

I upgraded to first. Quick and easy boarding. Comfortable seat with power and a nice IPA.

Probably not the fault of Delta but there was delay after delay after delay and I ended up getting home 4 hours later then I should have at 1:30 in the morning

No in flight service, no explanation - FC got service, C+ did not, unsure about Economy. No turbulence to speak of, so I guess another way to cut cost, or promote health and well being of Delta employees? Also, boarding in MEM combined zones, and with overhead space already full on both flights after Zone 2/ Diamond, presents a huge challenge to find a space for a bag. Delta, other than point A to B, is no longer reasonable to fly - very poor experiences, not even taking into account the chastising at the gate and rude crews, across the board.

It would have been better if the flight wasn't delayed by 2.5 hours

Delta’s staff is unmatched. From the gate agents, to the pilots, to the flight attendants… all top of the industry.

Delta flight Delay for ,more that two hours i.e original flight was 6.30 PM and it starts at 8.45 PM, When we connect Delta team for meal vouchers as it is late arrival in designation,But we did not get it as per delta policy , which is not good for mid night arrival,

Inexperienced boarding crew allowed too many bags on to a full flight and delayed takeoff causing a missed connection and unplanned overnight stay. There was a hotel at the airport but Delta would not pay for it offering only to shuttle me to an area hotel. Never even offerred so much as an apology by anyone working for Delta.

Everything you need to know for your flight from Midway to South Carolina

Information on your arrival and departure airports