$76 Find Cheap Flights from Chicago Midway Airport to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Midway to South Carolina departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Midway to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston2 stops$288
Myrtle Beach
Myrtle Beach2 stops$274
Greenville
Greenville1 stop$225
Columbia
Columbia1 stop$289
Charlotte
Charlotte1 stop$156
Charleston
Charleston2 stops$288
Myrtle Beach
Myrtle Beach2 stops$274
Greenville
Greenville1 stop$225
Columbia
Columbia1 stop$289
Charlotte
Charlotte1 stop$156

Book Cheap Midway to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Midway to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Midway to South Carolina

Tue, Apr 14 - Wed, Apr 29
Multiple Airlines Logo
7:30 am - 1:52 pm
MDW
-
CLT
5h 22m
1 stop
Multiple Airlines Logo
8:09 pm - 7:21 am
CLT
-
MDW
12h 12m
1 stop
$156Multiple Airlines
Fri, Apr 17 - Sat, May 2
Frontier Logo
9:14 am - 4:30 pm
MDW
-
CLT
6h 16m
1 stop
Frontier Logo
8:09 pm - 7:41 am
CLT
-
MDW
12h 32m
1 stop
$160Frontier
Tue, Apr 21 - Tue, Apr 28
Southwest Logo
6:00 pm - 8:55 pm
MDW
-
CLT
1h 55mnonstop
Southwest Logo
6:20 pm - 7:25 pm
CLT
-
MDW
2h 05mnonstop
$167Southwest
Tue, Apr 14 - Sat, May 2
Multiple Airlines Logo
7:30 am - 1:52 pm
MDW
-
CLT
5h 22m
1 stop
Multiple Airlines Logo
9:32 pm - 7:41 am
CLT
-
MDW
11h 09m
1 stop
$168Multiple Airlines
Tue, Apr 21 - Tue, Apr 28
Southwest Logo
3:00 pm - 9:40 pm
MDW
-
CLT
5h 40m
1 stop
Southwest Logo
6:20 pm - 7:25 pm
CLT
-
MDW
2h 05mnonstop
$177Southwest
Sat, Apr 18 - Wed, Apr 29
Frontier Logo
9:14 am - 4:35 pm
MDW
-
CLT
6h 21m
1 stop
Frontier Logo
8:09 pm - 7:21 am
CLT
-
MDW
12h 12m
1 stop
$178Frontier
Fri, Apr 17 - Mon, Apr 20
Frontier Logo
9:14 am - 4:30 pm
MDW
-
CLT
6h 16m
1 stop
Frontier Logo
4:47 pm - 10:21 pm
CLT
-
MDW
6h 34m
1 stop
$180Frontier
Thu, Apr 16 - Sat, May 2
Frontier Logo
9:14 am - 5:50 pm
MDW
-
CLT
7h 36m
1 stop
Frontier Logo
8:09 pm - 7:41 am
CLT
-
MDW
12h 32m
1 stop
$181Frontier
Fri, Jun 5 - Tue, Jun 9
Delta Logo
5:08 pm - 11:58 pm
MDW
-
MYR
5h 50m
1 stop
Delta Logo
4:16 pm - 10:17 pm
MYR
-
MDW
7h 01m
1 stop
$281Delta
Thu, May 28 - Sun, May 31
Delta Logo
10:59 am - 5:02 pm
MDW
-
CAE
5h 03m
1 stop
Delta Logo
5:50 pm - 9:09 pm
CAE
-
MDW
4h 19m
1 stop
$289Delta
Booking Insights

KAYAK's insights & trends for Midway to South Carolina flights

Get data-powered insights and trends into flights from Midway to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Chicago Midway Airport to South Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Chicago Midway Airport to South Carolina departing in May.

What is the cheapest Chicago Midway Airport to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Chicago Midway Airport found in the last 72 hours was to Charleston, at $257 round-trip. The most popular route is from Chicago Midway Airport (MDW) to Myrtle Beach (MYR), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $331.

What is the cheapest time of day to fly to South Carolina?

The average price for all round-trip flights from Chicago Midway Airport to South Carolina depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to South Carolina is generally in the afternoon, when round-trip flights cost $355 on average. Morning departures are around 4% cheaper than evening flights, on average. The most expensive time of day to fly to South Carolina is generally at night, which is peak travel time and where the average cost of a ticket is $388.

Can I save money by flying with a layover from Chicago Midway Airport to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $400, prices are generally cheapest when you fly direct.

What’s the cheapest day of the week to fly from Chicago Midway Airport to South Carolina?

The average price of all round-trip flights from Chicago Midway Airport to South Carolina clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to South Carolina on a Tuesday and more expensive on a Thursday. On your return trip to Chicago Midway Airport, you should consider flying back on a Thursday, and avoid Sundays for better deals.

Good to know

Low seasonJanuary
Cheapest flight$76
Best time to beat the crowds with an average 24% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Chicago Midway Airport to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Chicago Midway Airport to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago Midway Airport to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago Midway Airport to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Chicago Midway Airport to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago Midway Airport to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Chicago Midway Airport to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago Midway Airport to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Chicago Midway Airport to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Midway to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Chicago to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Midway to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4333 reviews
8.6Crew
8.1Boarding
7.5Entertainment
8.0Comfort
7.0Food
Airline reviews

Great flight. Good snacks and drinks. Grateful it was free. The flight from Nashville to louisville, i think her name was Tracy (not sure that's right) super awesome, nice and cheerful. She really enjoyed being at work today! She was the person who scanned the boarding pass on flight wn941. She should be recommended for a raise !

10.0 ExcellentGwen, Mar 2026
DAL - BNA
Read more Southwest reviews

Great flight. Good snacks and drinks. Grateful it was free. The flight from Nashville to louisville, i think her name was Tracy (not sure that's right) super awesome, nice and cheerful. She really enjoyed being at work today! She was the person who scanned the boarding pass on flight wn941. She should be recommended for a raise !

I liked it better when you were truer to your roots Am paying more for less fun

Southwest was greaat! The most expensive but the least upsetting for those we were flying to see.

I flew twice this week on Southwest, was delayed over 2 hours both ways. From Pittsburgh to Chicago it was due to weather but the gate agents, pilot etc were great at updating everyone. Today from Midway to Pittsburgh the plane had come from an international location, kept getting delayed, no information was given until we were delayed for the third time. It was ridiculous, whoever scheduled that plane to fly to Pittsburgh after didn’t consider a lot of things.

Boarding was easy. The seats are small and fairly uncomfortable

I was supposed to be on a later flight. When I showed up at the gate, the woman working there was extremely helpful getting moved up to this earlier flight.

We had a 5 hour delay on the tarmac in Baltimore

Long layover between flights to Long Island from BWI - need better coordination between flights

I elected to pay for the upgrades and found very little difference

The new seating arrangement is so over priced for what you get.

I took seat 15A in anticipation of window seat, there is no window.

The first class flight attendant was awful to everyone. Very rude; no customer service. She should not be working in first class.

Snacks and included beverages were appreciated. Boarding went smoothly. Plenty of overhead bin space. Seats get very uncomfortable after a couple of hours. After waiting 10 painful minutes for my walker, a very nice Delta guest agent pushed me in a wheelchair to the gate. It was finally delivered to me after another 15 minutes . Our checked bag was on the carousel long b4 I was able to retrieve it. Fortunately it was still there but somewhere along the way the straps we used to secure it were removed and and were not reattached. Wish I had made note of the agents name.

It was fine. 55 minute flight. No snacks or beverage service offered. Boarding went smoothly and my walker was waiting for me on the jet way.

Smaller plane for a longer flight than my first one. Doesn’t make sense.

The cabin temperature was nice and cool. The wifi was not working.

Flight late, the waited for a long time for “personal” to arrive at gate to dock the plane in Rochester. So annoying. This flight was expected, why aren’t personel available for the jet bridge?

As previously noted, this flight was great: departure was timely, the crew was friendly and attentive, and wifi connectivity was seamless. In particular, I appreciated that the flight attendant just told me to stow the laptop right before takeoff/landing, and trusted me to do so (which I did!).

Kayak botched up the booking, i had to call delta and fix. In the process Delta failed to honor my comfort plus seat assignment that i had previously.

Entertainment is ok! Boarding and seat with zone is terrible. I paid for the seats but you didn’t give me what I paid for which is exit isles.

Everything you need to know for your flight from Midway to South Carolina

Information on your arrival and departure airports