$102 Find Cheap Flights from Chicago Midway Airport to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Midway to South Carolina departing on 8/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Midway to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charlestonnonstop$272
Myrtle Beach
Myrtle Beach1 stop$256
Greenville
Greenville1 stop$252
Columbia
Columbia1 stop$289
Charlotte
Charlottenonstop$256
Charleston
Charlestonnonstop$272
Myrtle Beach
Myrtle Beach1 stop$256
Greenville
Greenville1 stop$252
Columbia
Columbia1 stop$289
Charlotte
Charlottenonstop$256

Book Cheap Midway to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Midway to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Midway to South Carolina

Thu, Oct 1 - Mon, Oct 5
Southwest Logo
6:20 am - 12:20 pm
MDW
-
GSP
5h 00m
1 stop
Southwest Logo
9:00 pm - 11:55 pm
GSP
-
MDW
3h 55m
1 stop
$252Southwest
Sat, Oct 10 - Wed, Oct 14
Delta Logo
10:35 am - 5:55 pm
MDW
-
MYR
6h 20m
1 stop
Delta Logo
6:00 am - 11:56 am
MYR
-
MDW
6h 56m
1 stop
$256Delta
Sat, Aug 8 - Thu, Aug 13
Southwest Logo
9:25 am - 12:20 pm
MDW
-
CLT
1h 55mnonstop
Southwest Logo
7:40 am - 3:25 pm
CLT
-
MDW
8h 45m
2 stops
$256Southwest
Thu, Oct 1 - Mon, Oct 5
Southwest Logo
6:20 am - 12:20 pm
MDW
-
GSP
5h 00m
1 stop
Southwest Logo
12:55 pm - 9:15 pm
GSP
-
MDW
9h 20m
2 stops
$257Southwest
Sat, Aug 8 - Thu, Aug 13
Southwest Logo
8:05 am - 6:20 pm
MDW
-
CLT
9h 15m
1 stop
Southwest Logo
6:30 pm - 7:30 pm
CLT
-
MDW
2h 00mnonstop
$257Southwest
Wed, Jul 15 - Wed, Jul 15
Southwest Logo
8:00 am - 11:10 am
MDW
-
CLT
2h 10mnonstop
Southwest Logo
7:05 pm - 8:10 pm
CLT
-
MDW
2h 05mnonstop
$259Southwest
Fri, Jul 31 - Mon, Aug 3
Frontier Logo
6:17 pm - 11:16 am
MDW
-
CLT
15h 59m
1 stop
Frontier Logo
6:41 pm - 11:07 am
CLT
-
MDW
17h 26m
2 stops
$265Frontier
Sat, Jun 20 - Sat, Jul 4
Delta Logo
9:17 am - 4:54 pm
MDW
-
CLT
6h 37m
1 stop
Delta Logo
12:19 pm - 3:40 pm
CLT
-
MDW
4h 21m
1 stop
$266Delta
Wed, Nov 11 - Sat, Nov 14
Delta Logo
1:05 pm - 5:55 pm
MDW
-
MYR
3h 50m
1 stop
Delta Logo
10:55 am - 4:25 pm
MYR
-
MDW
6h 30m
1 stop
$268Delta
Sat, Jul 4 - Sat, Jul 11
Southwest Logo
7:10 am - 12:20 pm
MDW
-
CLT
4h 10m
1 stop
Southwest Logo
6:00 pm - 7:00 pm
CLT
-
MDW
2h 00mnonstop
$269Southwest
Booking Insights

KAYAK's insights & trends for Midway to South Carolina flights

Get data-powered insights and trends into flights from Midway to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Chicago Midway Airport to South Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Chicago Midway Airport to South Carolina departing in July.

What is the cheapest Chicago Midway Airport to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Chicago Midway Airport found in the last 5 days was to Myrtle Beach, at $217 round-trip. The most popular route is from Chicago Midway Airport (MDW) to Charleston (CHS), and the cheapest round-trip airline ticket found on this route in the last 5 days was $293.

What is the cheapest time of day to fly to South Carolina?

The average price for all round-trip flights from Chicago Midway Airport to South Carolina depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to South Carolina is generally in the afternoon, when round-trip flights cost $341 on average. Morning departures are around 2% more expensive than evening flights, on average. The most expensive time of day to fly to South Carolina is generally at night, which is peak travel time and where the average cost of a ticket is $493.

Can I save money by flying with a layover from Chicago Midway Airport to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $401, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Chicago Midway Airport to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago Midway Airport to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago Midway Airport to South Carolina is October, when tickets cost $106 (return) on average. On the other hand, the most expensive months are December and January, when the average cost of round-trip tickets is $362 and $327 respectively.

What’s the cheapest day of the week to fly from Chicago Midway Airport to South Carolina?

The average price of all round-trip flights from Chicago Midway Airport to South Carolina clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to South Carolina on a Wednesday and more expensive on a Thursday. On your return trip to Chicago Midway Airport, you should consider flying back on a Wednesday, and avoid Sundays for better deals.

Good to know

Low seasonJanuary
Cheapest flight$102
Best time to beat the crowds with an average 25% drop in price.
Most popular time to fly with an average 8% increase in price.
Flight from Chicago Midway Airport to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Chicago Midway Airport to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago Midway Airport to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago Midway Airport to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Chicago Midway Airport to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago Midway Airport to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Chicago Midway Airport to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago Midway Airport to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Chicago Midway Airport to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Midway to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Chicago to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Midway to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4251 reviews
7.5Entertainment
7.0Food
8.1Boarding
8.6Crew
8.0Comfort
Airline reviews

there were two flight attendants that were up front...that were the best! They get KUDOs for making my trip only fantastic. Tell them Jeff said that!

10.0 ExcellentAnonymous, Jun 2026
OKC - LAS
Read more Southwest reviews

there were two flight attendants that were up front...that were the best! They get KUDOs for making my trip only fantastic. Tell them Jeff said that!

OKay. I sat in the back of the plane and it was really loud between babies and little kids, and adults who.like to talk a lot and loudly most of the flight.

Flight coming out of Buffalo was delayed, so we had to be rescheduled on another flight from Baltimore to Phoenix which means we had a long layover and got home 3.5 hours late. Shuttle to parking stopped at 10pm, so we had to pay for an Uber to the parking lot and got charged an extra day of parking since it was after midnight. Not the best experience. Long day!

Was fine, delayed and feels like southwest is always late

I don't know why flying out of Sarasota requires two plane changes.

The first time I flew in the extra legroom section. It was difficult to notice a difference. I had bad luck with my neighbors. The crew was okay. Southwest has reduced the live TV options.

The flight was smooth. The Southwest experience has degraded overall, but this one was okay.

No gluten free snacks. Seats felt worn or bare bones even though it was a new 737 MAX 8.

One major problem that was very unprofessional and uncalled for. Plane landed and we had to wait 20 minutes to get off the plane since they were waiting for someone to come to the gate to drive the jetway. Southwest couldn't have someone available and waiting for the plane to land? Is there only one person in Hobby airport who knows to drive the jetway? Was he at lunch? In the bar? Uncomfortable and uncalled for!

The checking experience in Orlando was terrible, almost missed the flight. Too many travelers and Southwest completely understaffed.

Long story short, it was one of the better flight experiences I've had in some time when compared with other airlines.

Flight was great! This flight from Atlanta was even better than when I paid for Comfort from SNA to Atlanta.

Connection flights should be spaced out farther because too close I missed my connection.

Definitely a southern flavor. Cordiality was evident even though no drinks or snacks were served.

On time! There were plenty of airport employees who were able to keep us moving in the right direction. The crew on the plane were professional.

Left /arrived on time. Decent seat space. Like the wifi/plugs and entertainment. Windows and tray table were kinda gross. Attendants didn't start snack service til 40mins before landing. Two rows before us, captain came on to say there's turbulence and recalled staff to seats. So, no drink/snack. Later, attendants didn't stop to see if we had trash nor even look our way. Felt invisible! Almost all pilot announcements were not only unintelligible, but so quiet. We had no idea what she said.

Average seat comfort, a drink and chips were provided, early boarding because we checked a carryon at the gate was nice. Ticket pricing shenanigans, including fees to pick a seat, check a bag, and get food onboard - evidence the industry is reinvigorating last century’s strategies- destroys the experience before one ever arrives at the airport. It’s difficult to recognize any value or sustain loyalty in the end-to-end process making air travel more drudgery than pleasure.

Gate agent was unhelpful for handicapped boarding. Flight attendant seemed untrained.

No service flight that took 5 hrs and a stop at an unscheduled airport. Crew and pilots did their jobs

Clean planes and not take my comfort class seat away.

Everything you need to know for your flight from Midway to South Carolina

Information on your arrival and departure airports