$96 Find Cheap Flights from Chicago to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Chicago to South Carolina departing on 8/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Chicago to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston2 stops$283
Myrtle Beach
Myrtle Beach2 stops$251
Greenville
Greenvillenonstop$269
Columbia
Columbia1 stop$217
Charlotte
Charlotte1 stop$259
Charleston
Charleston2 stops$283
Myrtle Beach
Myrtle Beach2 stops$251
Greenville
Greenvillenonstop$269
Columbia
Columbia1 stop$217
Charlotte
Charlotte1 stop$259

Book Cheap Chicago to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Chicago to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Chicago to South Carolina

Thu, Aug 20 - Sun, Aug 23
Delta Logo
6:40 am - 1:14 pm
ORD
-
CAE
5h 34m
1 stop
Delta Logo
6:08 pm - 11:57 pm
CAE
-
ORD
6h 49m
1 stop
$217Delta
Tue, Jul 14 - Tue, Jul 21
Multiple Airlines Logo
8:05 am - 11:39 am
ORD
-
MYR
26h 34m
2 stops
Multiple Airlines Logo
3:53 pm - 12:15 pm
MYR
-
ORD
21h 22m
1 stop
$251Multiple Airlines
Thu, Jul 9 - Sun, Jul 12
Contour Logo
11:20 am - 5:00 pm
ORD
-
CLT
4h 40m
1 stop
Contour Logo
6:05 pm - 10:40 am
CLT
-
ORD
17h 35m
1 stop
$259Contour
Fri, Jul 3 - Sun, Jul 5
Contour Logo
11:20 am - 5:00 pm
ORD
-
CLT
4h 40m
1 stop
Contour Logo
6:05 pm - 10:40 am
CLT
-
ORD
17h 35m
1 stop
$261Contour
Tue, Aug 4 - Wed, Aug 5
Southwest Logo
12:35 pm - 7:00 pm
MDW
-
CLT
5h 25m
2 stops
Southwest Logo
8:05 am - 9:00 am
CLT
-
MDW
1h 55mnonstop
$262Southwest
Tue, Aug 4 - Tue, Aug 11
United Airlines Logo
11:00 am - 2:19 pm
ORD
-
MYR
2h 19mnonstop
United Airlines Logo
6:21 pm - 7:56 pm
MYR
-
ORD
2h 35mnonstop
$263United Airlines
Mon, Aug 17 - Sat, Aug 22
Southwest Logo
5:30 am - 1:50 pm
MDW
-
MYR
7h 20m
2 stops
Southwest Logo
4:20 pm - 7:20 pm
MYR
-
MDW
4h 00m
1 stop
$263Southwest
Tue, Jul 14 - Tue, Jul 21
American Airlines Logo
9:00 am - 12:26 pm
ORD
-
MYR
2h 26mnonstop
American Airlines Logo
12:56 pm - 2:33 pm
MYR
-
ORD
2h 37mnonstop
$266American Airlines
Wed, Jul 15 - Tue, Jul 28
United Airlines Logo
7:10 am - 10:28 am
ORD
-
CAE
2h 18mnonstop
United Airlines Logo
11:03 am - 12:25 pm
CAE
-
ORD
2h 22mnonstop
$269United Airlines
Tue, Aug 4 - Sat, Aug 8
American Airlines Logo
8:59 pm - 11:58 pm
ORD
-
GSP
1h 59mnonstop
American Airlines Logo
6:45 am - 8:06 am
GSP
-
ORD
2h 21mnonstop
$270American Airlines
Booking Insights

KAYAK's insights & trends for Chicago to South Carolina flights

Get data-powered insights and trends into flights from Chicago to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Chicago to South Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Chicago to South Carolina departing in August.

What is the cheapest Chicago to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Chicago found in the last 5 days was to Myrtle Beach, at $217 round-trip. The most popular route is from Chicago O'Hare Intl Airport (ORD) to Charleston (CHS), and the cheapest round-trip airline ticket found on this route in the last 5 days was $274.

What is the cheapest time of day to fly to South Carolina?

The average price for all round-trip flights from Chicago to South Carolina depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to South Carolina is generally in the evening, when round-trip flights cost $371 on average. Morning departures are around 3% more expensive than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the morning, which is peak travel time and where the average cost of a ticket is $380.

Can I save money by flying with a layover from Chicago to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $363, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Chicago to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago to South Carolina is September, when tickets cost $50 (return) on average. On the other hand, the most expensive months are November and October, when the average cost of round-trip tickets is $615 and $614 respectively.

What’s the cheapest day of the week to fly from Chicago to South Carolina?

The average price of all round-trip flights from Chicago to South Carolina clicked on KAYAK for each day over the last 12 months.

For Chicago to South Carolina, Monday is the cheapest day to fly on average and Sunday is the most expensive. Flying from South Carolina back to Chicago, the best deals are generally found on Friday, with Monday being the most expensive.

How far in advance should I book a flight from Chicago to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Chicago to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Chicago to South Carolina, you should book around 4 weeks before departure, which saves you about 56% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 4 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$96
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Chicago O'Hare Airport to Savannah

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Chicago to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Chicago to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Chicago to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Chicago to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Chicago to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Chicago to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Chicago to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4241 reviews
7.5Entertainment
8.1Boarding
7.0Food
8.6Crew
8.0Comfort
Airline reviews

Flight was constantly delayed with significant changes in time, it was supposed to get to Colorado Springs at 8:30 PM but it got there after midnight.

2.0 MediocreMarcela, Jun 2026
DAL - COS
Read more Southwest reviews

Flight was constantly delayed with significant changes in time, it was supposed to get to Colorado Springs at 8:30 PM but it got there after midnight.

Over a 3 hour flight. The turbulence was almost imperceptible except for 2 short periods which were not bad and over quickly. The attendants claimed "Safety first" and sat looking at their phones for 3 hours with no drink or snack service. This isn't the first time with Southwest. I thinkit may be there new plan of operation. Oh, and it was June 18, Southwest's Birthday which offered free drinks. NOT.

Flight was delayed, full flight and I had to change gates. Southwest flights are always late later in the day.

Flight was delayed over 3 hours. Planes were dirty. Staff indifferent. And they serve vegan pretzels as snacks.

It was great. The gate staff were very helpful in Portland when my son forgot his rolling bag and had to go back to get it just in time to make it on the plane. We really appreciate that. Great job!

Airline is not very senior friendly. Flights are late, forcing us to run to the connecting flight. Food is awful. Wish they would go back to pretzels and peanuts. During flight, pressurization isn’t quite right and all of our ears get plugged. Everything is nickel and dime, charging for boarding, seat selection and legroom. While a screen at the desk in the gate area says check your roll on bag now for free due to space limitation, the employee at the desk will not check the bag without a $100 fee. Insane.

Kayak could’ve posted the correct gate number. Almost missed my flight.

Slow boarding, limited food and drink portions. Bad delays and turbulence

there were two flight attendants that were up front...that were the best! They get KUDOs for making my trip only fantastic. Tell them Jeff said that!

OKay. I sat in the back of the plane and it was really loud between babies and little kids, and adults who.like to talk a lot and loudly most of the flight.

Flight got canceled 4 times, missed my connecting flight due to delays, have to wait to go home tomorrow

Third flight in two months where the crew was not there. Comfort seating does not guarantee overhead bin space. Passengers with children are allowed on the plane first - if you are flying to and from Orlando, this means half the plane has boarded before you get on. And somehow all the bin space is taken up. 3 out of 5 flights have had issues with equipment or procedure. Some of these instances caused the flight to be delayed because of a "nuisance" light. One time it was a bag that had been brought on board but did not belong to anyone so we had to return to the gate. Last night we were told the "AC" on the plane doesn't work well and we're 10th for take off- because the crew was late - and that it will get cool when we're in the air. Not sure if this is usual, but I didn't think flight crew could jump seat in first class. Movie and TV selection has not been refreshed for several months- flying one to two round trips each month easily exhausts the list of content.

Great experience nice pilot very soft and easy landing and take off

We sat on the runway for over an hour before departure. That was unwelcome.

Horrible. Faucet in sink not working, wifi not working. Didn’t bring food or snacks

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

From checking to boarding, it was a seamless experience. The service agents were so helpful. The flight crew was so pleasant.

Gate agent showed up 20 minutes before boarding and was not at all friendly. Had to take this flight due to the one on the day before being cancelled and any later options were already full with long standby lists. Despite having paid for Delta Comfort seats, Delta did not allow me (or anyone) to choose their seat. The agent assigned them for everyone just prior to boarding. Self seat selection was allowed on the original flight. Flight staff was great - very friendly.

Flight attendants were great. Cheerful, upbeat and friendly. Jet, in particular, was fantastic.

I have Precheck. Flew HPN to DEN and return this past weekend. Delta didn't attach my Precheck number to this trip. So it was waiting in general line especially in Denver. Unavailable.

Horrible! Several delays and then was cancelled! I spent over 24 hours in the airport and was unable to get a hotel or food voucher.

Boarded early; and arrived home 40 mins early. After a long flight, it’s nice to be back home early. These flights have no amenities; no snacks. So need to bring your own

A long delay. Don't travel late in the day.

Super friendly with lots of drink options an entertainment. Friendly crew.

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

Several missed and almost missed connections. It felt like everything was being patched together last minute without enough resources and it ended up being an extremely stressful experience that basically ruined our weekend on the west coast. What a waste.

Crew was friendly. Seats are too narrow, particularly when a big person is in the adjacent seat, but I understand this is due to smaller planes usually flight into Lincoln. I have experienced several flight delays going out and coming into Lincoln airport, I say maybe 50% or higher of the flights I've taken out of this airport have been delayed.

Great flight. Boarded efficiently. Arrived early at CLT. There was no in flight entertainment on this aircraft. Great crew.

The seat was comfortable. There was a lot of turbulence. If it weren't for that,it would have been okay.

Poor communication, flight was delayed for preventable reasons. I missed my connection.

Significant delays on my trip to Chicago and my trip back to NY

Delayed by 5 hours and I had to wit in the airport for more than 6+ hours.

I’ve got 31F seat and window seat . My 2 co passengers was AA crew members and they were very rude attitude and when I was going to use bathroom their gestures was very different and awkward and the guy beside me completely occupied the hand rest and I was really uncomfortable

It was so much better than expected, Ohare is not such a pleasant experience but American Airlines with the new, clean aeroplane and free Wi-Fi was outstanding and the crew so pleasant and helpful.

It wa sort of on time; the cab was left with some trash

American Airlines II: Delay Boogaloo. Multiple gate changes, delays, boarded and then MORE delays. I hate to say this won’t matter, but posting stuff about major corporations in 2026 is a post-modern “scream into the void.” Was multiple hours late coming home, so there you go.

The airplane was an old model, the overhead didn’t have enough room for people’s items and made boarding and boarding disappointing and stressful. Crew allowed passengers to bring more than the permitted baggage sizes.

Original flight was on time, then late, then changed gates...4 times. Once our newest plane came in, it was fine.

I almost missed my flight and they helped me out enormously

Delays experienced in boarding/take off due to incoming plane delayed. However, the boarding time/depart time in the app was significantly delayed in providing these updates. Usually not updated until an hour after we should have already boarded. Poorly managed.

Everything you need to know for your flight from Chicago to South Carolina

Cabin class types available on flights to South Carolina

Cabin classes available on flights to South Carolina. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.