ORD - MSL

$417 Find Cheap Flights from Chicago to Florence - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest one-way
$746
Typical prices: $413-$413
Multiple Airlines
Thu 1/4
ORD - MSL • 2 stops
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Booking Insights
Flight Deals

Cheap Flights from Chicago to Florence (ORD-MSL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Chicago to Florence

Thu, Nov 19 - Mon, Nov 23
Contour Logo
2:55 pm - 6:50 pmORD  Chicago O'Hare Intl-MSL Florence Muscle Shoals
27h 55m2 stops Kirksville Cannon Memorial Dallas/Fort Worth
Contour Logo
7:50 am - 2:15 pmMSL  Florence Muscle Shoals-ORD Chicago O'Hare Intl
30h 25m2 stops Dallas/Fort Worth Kirksville Cannon Memorial
$417Contour
Thu, Nov 19 - Mon, Nov 23
Multiple Airlines Logo
2:55 pm - 6:50 pmORD  Chicago O'Hare Intl-MSL Florence Muscle Shoals
27h 55m2 stops Kirksville Cannon Memorial Dallas/Fort Worth
Multiple Airlines Logo
12:25 pm - 1:44 pmMSL  Florence Muscle Shoals-ORD Chicago O'Hare Intl
25h 19m3 stops Charlotte Douglas Miami Atlanta Hartsfield-Jackson
$488Multiple Airlines
Wed, Nov 18 - Sun, Nov 22
Multiple Airlines Logo
2:55 pm - 6:50 pmORD  Chicago O'Hare Intl-MSL Florence Muscle Shoals
27h 55m2 stops Kirksville Cannon Memorial Dallas/Fort Worth
Multiple Airlines Logo
12:25 pm - 12:43 amMSL  Florence Muscle Shoals-ORD Chicago O'Hare Intl
12h 18m2 stops Charlotte Douglas Orlando
$537Multiple Airlines
Thu, Nov 19 - Mon, Nov 23
Multiple Airlines Logo
10:29 am - 6:50 pmORD  Chicago O'Hare Intl-MSL Florence Muscle Shoals
8h 21m1 stop Dallas/Fort Worth
Multiple Airlines Logo
12:25 pm - 11:34 pmMSL  Florence Muscle Shoals-ORD Chicago O'Hare Intl
35h 09m2 stops Charlotte Douglas Fort Lauderdale
$539Multiple Airlines
Tue, Nov 17 - Sat, Nov 21
Multiple Airlines Logo
4:36 pm - 6:50 pmORD  Chicago O'Hare Intl-MSL Florence Muscle Shoals
26h 14m1 stop Dallas/Fort Worth
Multiple Airlines Logo
12:25 pm - 12:43 amMSL  Florence Muscle Shoals-ORD Chicago O'Hare Intl
12h 18m2 stops Charlotte Douglas Orlando
$555Multiple Airlines
Wed, Nov 18 - Sun, Nov 22
Multiple Airlines Logo
8:59 am - 6:50 pmORD  Chicago O'Hare Intl-MSL Florence Muscle Shoals
9h 51m1 stop Dallas/Fort Worth
Multiple Airlines Logo
12:25 pm - 11:34 pmMSL  Florence Muscle Shoals-ORD Chicago O'Hare Intl
35h 09m2 stops Charlotte Douglas Fort Lauderdale
$574Multiple Airlines
Wed, Nov 18 - Sun, Nov 22
Multiple Airlines Logo
2:55 pm - 6:50 pmORD  Chicago O'Hare Intl-MSL Florence Muscle Shoals
27h 55m2 stops Kirksville Cannon Memorial Dallas/Fort Worth
Multiple Airlines Logo
12:25 pm - 3:57 pmMSL  Florence Muscle Shoals-ORD Chicago O'Hare Intl
27h 32m3 stops Charlotte Douglas Orlando Baltimore/Washington
$609Multiple Airlines
Thu, Nov 19 - Mon, Nov 23
Multiple Airlines Logo
10:29 am - 6:50 pmORD  Chicago O'Hare Intl-MSL Florence Muscle Shoals
8h 21m1 stop Dallas/Fort Worth
Multiple Airlines Logo
7:50 am - 7:47 amMSL  Florence Muscle Shoals-ORD Chicago O'Hare Intl
23h 57m1 stop Dallas/Fort Worth
$612Multiple Airlines
Tue, Nov 17 - Sat, Nov 21
Multiple Airlines Logo
4:36 pm - 6:50 pmORD  Chicago O'Hare Intl-MSL Florence Muscle Shoals
26h 14m1 stop Dallas/Fort Worth
Multiple Airlines Logo
7:50 am - 6:32 pmMSL  Florence Muscle Shoals-ORD Chicago O'Hare Intl
10h 42m1 stop Dallas/Fort Worth
$644Multiple Airlines
Thu, Nov 19 - Mon, Nov 23
Multiple Airlines Logo
7:31 am - 11:50 amORD  Chicago O'Hare Intl-MSL Florence Muscle Shoals
28h 19m3 stops Atlanta Hartsfield-Jackson New York LaGuardia Charlotte Douglas
Multiple Airlines Logo
12:25 pm - 1:44 pmMSL  Florence Muscle Shoals-ORD Chicago O'Hare Intl
25h 19m3 stops Charlotte Douglas Miami Atlanta Hartsfield-Jackson
$715Multiple Airlines
Booking Insights

Price, demand and travel trends for Chicago O'Hare Intl Airport to Florence flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Which airline is the cheapest to fly from Chicago O'Hare Intl Airport to Florence?

Contour ($417) offered the cheapest round-trip ticket from Chicago O'Hare Intl Airport to Florence in the last 5 days.

Key details for Chicago O'Hare Intl Airport to Florence flights

Cheapest flight

$417
Round-trip flight from Chicago O'Hare Intl Airport to Florence

When to book flights from Chicago to Florence

Are your dates flexible? Find out the best times to travel from Chicago to Florence based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Chicago O'Hare Intl Airport to Florence flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • Do I need a passport to fly from Chicago O'Hare Intl Airport to Florence?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • Have flight prices from Chicago O'Hare Intl Airport to Florence changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $417 to $787. That means the highest observed fare was about 88% higher than the lowest one.

  • How are flight prices from Chicago O'Hare Intl Airport to Florence looking right now?

    One-way fares from Chicago O'Hare Intl Airport to Florence are currently higher than usual. Average one-way flight prices are about $746, which is 80% above the typical average for this route.

  • Which airports can I use when flying from Chicago O'Hare Intl Airport to Florence?

    Flights from Chicago O'Hare Intl Airport to Florence usually depart from Chicago O'Hare Intl (ORD) and arrive at Florence Muscle Shoals (MSL).

More options for your flight from Chicago to Florence

Complete your trip to Florence with a hotel stay or car rental