CMH - TYS

$111 Find Cheap Flights from Columbus to Knoxville - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$250
Typical prices: $284-$506
Delta
Sat 12/1Tue 12/4
CMH - TYS • 1 stop
Cheapest one-way
$111
Typical prices: $188-$303
Multiple Airlines
Sat 10/27
CMH - TYS • 2 stops
Nonstop flights
There are currently no direct flights between Columbus Airport and Knoxville. You'll need to take a connecting flight to reach the destination.
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When to travel
Cheapest • 26% price drop
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Cheapest • Avg $289 (round-trip)
Shortest trip • 3h 54m (one-way)
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Cheap Flights from Columbus to Knoxville (CMH-TYS)

 

Cheap flights from Columbus to Knoxville with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.

Tue, Dec 1 - Fri, Dec 4
Delta Logo
7:05 am - 11:27 amCMH  Columbus-TYS Knoxville McGhee Tyson
4h 22m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:10 pm - 9:03 pmTYS  Knoxville McGhee Tyson-CMH Columbus
3h 53m1 stop Detroit Metropolitan Wayne County
$250Delta
Tue, Dec 1 - Fri, Dec 4
Delta Logo
7:05 am - 11:27 amCMH  Columbus-TYS Knoxville McGhee Tyson
4h 22m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:10 pm - 9:03 pmTYS  Knoxville McGhee Tyson-CMH Columbus
3h 53m1 stop Detroit Metropolitan Wayne County
$257Delta
Mon, Nov 9 - Fri, Nov 13
Southwest Logo
5:35 pm - 9:45 pmCMH  Columbus-TYS Knoxville McGhee Tyson
4h 10m1 stop Baltimore/Washington
Southwest Logo
12:50 pm - 8:30 pmTYS  Knoxville McGhee Tyson-CMH Columbus
7h 40m1 stop Orlando
$258Southwest
Mon, Nov 9 - Fri, Nov 13
Southwest Logo
12:10 pm - 8:35 pmCMH  Columbus-TYS Knoxville McGhee Tyson
8h 25m2 stops Chicago Midway Nashville Intl
Southwest Logo
7:25 pm - 10:35 pmTYS  Knoxville McGhee Tyson-CMH Columbus
3h 10m1 stop Nashville Intl
$263Southwest
Fri, Oct 30 - Mon, Nov 2
Southwest Logo
5:40 pm - 9:35 pmCMH  Columbus-TYS Knoxville McGhee Tyson
3h 55m1 stop Baltimore/Washington
Southwest Logo
7:25 pm - 10:30 pmTYS  Knoxville McGhee Tyson-CMH Columbus
3h 05m1 stop Nashville Intl
$286Southwest
Mon, Oct 26 - Fri, Oct 30
Southwest Logo
5:40 pm - 9:35 pmCMH  Columbus-TYS Knoxville McGhee Tyson
3h 55m1 stop Baltimore/Washington
Southwest Logo
8:20 am - 12:00 pmTYS  Knoxville McGhee Tyson-CMH Columbus
3h 40m1 stop Baltimore/Washington
$286Southwest
Sat, Jan 30 - Wed, Feb 3
United Airlines Logo
12:20 pm - 4:54 pmCMH  Columbus-TYS Knoxville McGhee Tyson
4h 34m1 stop Chicago O'Hare Intl
United Airlines Logo
5:55 pm - 10:24 pmTYS  Knoxville McGhee Tyson-CMH Columbus
4h 29m1 stop Chicago O'Hare Intl
$317United Airlines
Sat, Jan 30 - Wed, Feb 3
United Airlines Logo
7:00 am - 2:47 pmCMH  Columbus-TYS Knoxville McGhee Tyson
7h 47m2 stops Newark Washington, D.C. Dulles Intl
United Airlines Logo
7:10 pm - 11:44 pmTYS  Knoxville McGhee Tyson-CMH Columbus
4h 34m1 stop Washington, D.C. Dulles Intl
$322United Airlines
Mon, Oct 26 - Thu, Nov 5
American Airlines Logo
5:24 am - 11:05 amCMH  Columbus-TYS Knoxville McGhee Tyson
5h 41m1 stop Chicago O'Hare Intl
American Airlines Logo
6:48 am - 11:50 amTYS  Knoxville McGhee Tyson-CMH Columbus
5h 02m1 stop Washington, D.C. Reagan-National
$367American Airlines
Wed, Oct 28 - Fri, Nov 6
American Airlines Logo
11:43 am - 4:18 pmCMH  Columbus-TYS Knoxville McGhee Tyson
4h 35m1 stop Charlotte Douglas
American Airlines Logo
4:59 pm - 11:21 pmTYS  Knoxville McGhee Tyson-CMH Columbus
6h 22m1 stop Chicago O'Hare Intl
$457American Airlines

Price, demand and travel trends for Columbus Airport to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Columbus Airport to Knoxville?

Round-trip flights from Columbus Airport to Knoxville typically range from $284 to $506. The lowest price found in the past 5 days was $250, on Delta.

What's the cheapest day of the week to fly from Columbus Airport to Knoxville?

Based on deals KAYAK users found in the last 12 months, Thursday is the cheapest day of the week to fly from Columbus Airport to Knoxville. It’s 12% cheaper than the average day, while Wednesday is the most expensive, with prices 64% higher.

Key details for Columbus Airport to Knoxville flights

Low season

August

Cheapest flight

$111
Beat the crowds with an average 35% drop in travelers.
One-way flight from Columbus Airport to Knoxville

When to book flights from Columbus to Knoxville

Are your dates flexible? Find out the best times to travel from Columbus to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Columbus Airport to Knoxville flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Columbus Airport to Knoxville?

    Only Economy Class is available on flights from Columbus Airport to Knoxville.

  • How long is a flight from Columbus Airport to Knoxville?

    A nonstop flight from Columbus Airport to Knoxville takes 00m, covering 296 miles.

  • Do I need a passport to fly from Columbus Airport to Knoxville?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Columbus Airport to Knoxville flight?

    Round-trip flights from Columbus Airport to Knoxville range from $284 to $506, with an average of $320 over the past 12 months. Anything below $284 counts as a good deal.

  • Have flight prices from Columbus Airport to Knoxville changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $250 to $934. That means the highest observed fare was about 4x higher than the lowest one.

  • How are flight prices from Columbus Airport to Knoxville looking right now?

    One-way fares from Columbus Airport to Knoxville are currently lower than usual. Average one-way flight prices are about $125, which is 55% below the typical average for this route.

  • What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

    Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:

    • Budget
    • Alamo
    • Enterprise Rent-A-Car
    • Thrifty
    • Avis

  • Which airports can I use when flying from Columbus Airport to Knoxville?

    Flights from Columbus Airport to Knoxville usually depart from Columbus (CMH) and arrive at Knoxville McGhee Tyson (TYS).

  • Which airports do connecting flights from Columbus Airport to Knoxville pass through?

    One-stop flights from Columbus Airport to Knoxville most commonly connect through:

    • Charlotte Douglas (CLT) - 64% of one-stop connections
    • Washington, D.C. Dulles Intl (IAD) - 18% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 14% of one-stop connections
    • Nashville Intl (BNA) - 4% of one-stop connections

  • Can I save money by using flexible dates for flights from Columbus Airport to Knoxville?

    Yes. Flexible dates can save you up to 47% on flights from Columbus Airport to Knoxville. Thursday is the cheapest departure day at $284 round-trip on average, while Wednesday is the most expensive at $526, a difference of $242.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Columbus Airport to Knoxville?

    Flying via Charlotte Douglas (CLT) gives the shortest average 1-stop total travel time at 3h 54m, compared with 4h 23m via Washington, D.C. Dulles Intl (IAD) and 4h 40m via Atlanta Hartsfield-Jackson (ATL).

Your guide to booking Columbus Airport to Knoxville flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Thursday departure and avoid flying on Wednesday. On this route, Thursday flights average $284, about $242 less than Wednesday fares (46% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Columbus Airport to Knoxville trip for November. Fares historically average $238 round-trip in that month - typically $388 less than the most expensive month, which is May (based on the last 12 months).

More options for your flight from Columbus to Knoxville

Complete your trip to Knoxville with a hotel stay or car rental