$333 Find Cheap Flights from Denver to Santa Cruz de la Sierra - Compare and Save

Flights from Denver to Santa Cruz de la Sierra usually depart from Denver Intl (DEN) and arrive at Santa Cruz de la Sierra Viru Viru Intl (VVI).

Only Economy Class is available on flights from Denver to Santa Cruz de la Sierra.

Most connecting flights from Denver to Santa Cruz de la Sierra pass through Panama City Tocumen Intl (PTY), which handles 100% of one-stop traffic on this route. Other layover airports each see under 5%.

Yes. Being flexible with your travel dates can save you up to 60% on the Denver to Santa Cruz de la Sierra route. Monday is the cheapest departure day at $588 round-trip on average, while Sunday is the most expensive at $1,444, a difference of $856. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

A nonstop flight from Denver to Santa Cruz de la Sierra takes 0h 00m, covering 4,786 miles.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $684 to $3,004. That means the highest observed fare was about 4x higher than the lowest one.

One-way fares from Denver to Santa Cruz de la Sierra are currently higher than usual. Average one-way flight prices are about $404, which is 22% above the typical average for this route.

Santa Cruz de la Sierra is 2 hours ahead of Denver (Bolivia Time vs Mountain Time). Plan for the time shift when scheduling connections or first-day activities.

Round-trip flights from Denver to Santa Cruz de la Sierra range from $606 to $995, with an average of $776 over the past 12 months. Anything below $606 counts as a good deal.