DEN - VVI

$878 Find Cheap Flights from Denver to Santa Cruz de la Sierra - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$878
Typical prices: $606-$854
United Airlines
Tue 11/20Sun 12/2
DEN - VVI • 2 stops
When to travel
Cheapest • 19% price drop
Most popular
Good to know
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Good to know
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Flight Deals

Cheap Flights from Denver to Santa Cruz de la Sierra (DEN-VVI)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to Santa Cruz de la Sierra

Fri, Nov 20 - Wed, Dec 2
United Airlines Logo
11:59 pm - 10:38 pmDEN  Denver Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
43h 39m2 stops Newark Panama City Tocumen Intl
United Airlines Logo
11:34 am - 10:24 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-DEN Denver Intl
37h 50m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
$878United Airlines
Sat, Nov 21 - Wed, Dec 2
United Airlines Logo
7:15 pm - 3:37 amDEN  Denver Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
29h 22m2 stops Newark Panama City Tocumen Intl
United Airlines Logo
11:34 am - 10:24 amVVI  Santa Cruz de la Sierra Viru Viru Intl-DEN Denver Intl
25h 50m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl
$892United Airlines
Thu, Mar 11 - Fri, Mar 26
United Airlines Logo
6:00 am - 3:55 amDEN  Denver Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
18h 55m2 stops Newark Panama City Tocumen Intl
United Airlines Logo
9:56 am - 4:23 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-DEN Denver Intl
32h 27m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl
$1,123United Airlines
Fri, Nov 20 - Wed, Dec 2
Multiple Airlines Logo
3:52 pm - 3:50 amDEN  Denver Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
32h 58m1 stop Miami
Multiple Airlines Logo
11:34 am - 7:40 amVVI  Santa Cruz de la Sierra Viru Viru Intl-DEN Denver Intl
23h 06m2 stops Panama City Tocumen Intl Miami
$1,183Multiple Airlines
Sat, Nov 21 - Wed, Dec 2
Multiple Airlines Logo
3:52 pm - 10:38 pmDEN  Denver Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
27h 46m2 stops Miami Panama City Tocumen Intl
Multiple Airlines Logo
11:35 pm - 7:40 amVVI  Santa Cruz de la Sierra Viru Viru Intl-DEN Denver Intl
35h 05m1 stop Miami
$1,185Multiple Airlines
Thu, Mar 11 - Thu, Mar 25
Copa Airlines Logo
8:40 pm - 3:55 amDEN  Denver Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
28h 15m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:55 am - 6:04 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-DEN Denver Intl
19h 09m1 stop Panama City Tocumen Intl
$1,248Copa Airlines
Sat, Nov 21 - Wed, Dec 2
Copa Airlines Logo
9:49 pm - 10:38 pmDEN  Denver Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
21h 49m1 stop Panama City Tocumen Intl
Copa Airlines Logo
11:34 am - 5:10 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-DEN Denver Intl
32h 36m1 stop Panama City Tocumen Intl
$1,302Copa Airlines
Fri, Nov 20 - Wed, Dec 2
Multiple Airlines Logo
3:52 pm - 3:50 amDEN  Denver Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
32h 58m1 stop Miami
Multiple Airlines Logo
11:35 pm - 7:40 amVVI  Santa Cruz de la Sierra Viru Viru Intl-DEN Denver Intl
35h 05m1 stop Miami
$1,437Multiple Airlines
Booking Insights

Price, demand and travel trends for Denver to Santa Cruz de la Sierra flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Denver to Santa Cruz de la Sierra?

Round-trip flights from Denver to Santa Cruz de la Sierra typically range from $606 to $854. The lowest price found in the past 5 days was $878, on United Airlines.

What's the cheapest day of the week to fly from Denver to Santa Cruz de la Sierra?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Denver to Santa Cruz de la Sierra. It’s 20% cheaper than the average day, while Sunday is the most expensive, with prices 93% higher.

Key details for Denver to Santa Cruz de la Sierra flights

Low season

September

Cheapest flight

$878
Beat the crowds with an average 81% drop in travelers.
The most popular month to fly with an average 34% increase in travelers.
Round-trip flight from Denver to Santa Cruz de la Sierra

When to book flights from Denver to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Denver to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Denver to Santa Cruz de la Sierra flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Denver to Santa Cruz de la Sierra?

    Only Economy Class is available on flights from Denver to Santa Cruz de la Sierra.

  • Do I need a passport to fly from Denver to Santa Cruz de la Sierra?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Denver to Santa Cruz de la Sierra flight?

    Round-trip flights from Denver to Santa Cruz de la Sierra range from $606 to $854, with an average of $745 over the past 12 months. Anything below $606 counts as a good deal.

  • Have flight prices from Denver to Santa Cruz de la Sierra changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $878 to $1,437. That means the highest observed fare was about 63% higher than the lowest one.

  • Which airports can I use when flying from Denver to Santa Cruz de la Sierra?

    Flights from Denver to Santa Cruz de la Sierra usually depart from Denver Intl (DEN) and arrive at Santa Cruz de la Sierra Viru Viru Intl (VVI).

  • Which airports do connecting flights from Denver to Santa Cruz de la Sierra pass through?

    Most connecting flights from Denver to Santa Cruz de la Sierra pass through Panama City Tocumen Intl (PTY), which handles 100% of one-stop traffic on this route.

  • Can I save money by using flexible dates for flights from Denver to Santa Cruz de la Sierra?

    Yes. Flexible dates can save you up to 59% on flights from Denver to Santa Cruz de la Sierra. Wednesday is the cheapest departure day at $602 round-trip on average, while Sunday is the most expensive at $1,444, a difference of $842.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What is the time difference between Denver and Santa Cruz de la Sierra?

    Santa Cruz de la Sierra is 3 hours ahead of Denver (Bolivia Time vs Mountain Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking Denver to Santa Cruz de la Sierra flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Sunday. On this route, Wednesday flights average $602, about $842 less than Sunday fares (58% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Denver to Santa Cruz de la Sierra trip for February. Fares historically average $606 round-trip in that month - typically $1,163 less than the most expensive month, which is December (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santa Cruz de la Sierra Viru Viru Intl Airport.

    • Sun Hotel

More options for your flight from Denver to Santa Cruz de la Sierra

Complete your trip to Santa Cruz de la Sierra with a hotel stay or car rental