$131 Find Cheap Flights from Denver to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to South America departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Denver to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$453
Bogotá
Bogotá1 stop$343
Sao Paulo
Sao Paulo3 stops$620
Rio de Janeiro
Rio de Janeiro1 stop$819
Santiago
Santiago1 stop$532
Cartagena
Cartagena1 stop$366
Quito
Quito1 stop$388
Guayaquil
Guayaquil1 stop$347
Cali
Cali2 stops$402
Cusco
Cusco2 stops$673
Pereira
Pereira2 stops$419
Georgetown
Georgetown1 stop$463
Montevideo
Montevideo1 stop$920
Barranquilla
Barranquilla1 stop$410
Santa Marta
Santa Marta2 stops$481
Florianopolis
Florianopolis1 stop$816
Lima
Lima1 stop$453
Bogotá
Bogotá1 stop$343
Sao Paulo
Sao Paulo3 stops$620
Rio de Janeiro
Rio de Janeiro1 stop$819
Santiago
Santiago1 stop$532
Cartagena
Cartagena1 stop$366
Quito
Quito1 stop$388
Guayaquil
Guayaquil1 stop$347
Cali
Cali2 stops$402
Cusco
Cusco2 stops$673
Pereira
Pereira2 stops$419
Georgetown
Georgetown1 stop$463
Montevideo
Montevideo1 stop$920
Barranquilla
Barranquilla1 stop$410
Santa Marta
Santa Marta2 stops$481
Florianopolis
Florianopolis1 stop$816

Book Cheap Denver to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to South America

Sat, Nov 29 - Thu, Dec 4
United Airlines Logo
5:00 am - 10:35 pmDEN-BOG
15h 35m1 stop
United Airlines Logo
8:15 am - 7:46 pmBOG-DEN
13h 31m1 stop
$343United Airlines
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Wed, Nov 26 - Thu, Nov 27
American Airlines Logo
8:50 am - 10:10 pmDEN-BOG
11h 20m1 stop
American Airlines Logo
11:55 pm - 3:15 pmBOG-DEN
17h 20m2 stops
$348American Airlines
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Sat, Jan 31 - Sun, Feb 8
United Airlines Logo
3:39 pm - 10:35 pmDEN-BOG
28h 56m1 stop
United Airlines Logo
8:15 am - 10:06 pmBOG-DEN
15h 51m1 stop
$350United Airlines
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Tue, Feb 3 - Tue, Feb 10
American Airlines Logo
8:44 am - 10:10 pmDEN-BOG
11h 26m2 stops
American Airlines Logo
11:55 pm - 11:34 amBOG-DEN
13h 39m2 stops
$356American Airlines
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Mon, Jan 19 - Fri, Jan 30
Copa Airlines Logo
9:38 pm - 5:03 pmDEN-BOG
17h 25m1 stop
Copa Airlines Logo
7:00 am - 5:16 pmBOG-DEN
12h 16m1 stop
$361Copa Airlines
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Mon, Feb 2 - Tue, Feb 10
Delta Logo
12:30 am - 7:30 pmDEN-BOG
17h 00m1 stop
Delta Logo
5:00 am - 10:50 pmBOG-DEN
19h 50m2 stops
$363Delta
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Tue, Dec 2 - Wed, Dec 10
Copa Airlines Logo
9:36 pm - 11:07 amDEN-BOG
11h 31m1 stop
Copa Airlines Logo
8:40 am - 5:17 pmBOG-DEN
10h 37m1 stop
$374Copa Airlines
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Mon, Dec 8 - Thu, Dec 11
Delta Logo
12:50 am - 2:17 pmDEN-CTG
11h 27m1 stop
Delta Logo
3:32 pm - 12:07 amCTG-DEN
10h 35m1 stop
$406Delta
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Tue, Mar 3 - Tue, Mar 10
LATAM Airlines Logo
12:00 pm - 5:00 amDEN-LIM
15h 00m1 stop
LATAM Airlines Logo
12:15 pm - 11:54 pmLIM-DEN
12h 39m1 stop
$468LATAM Airlines
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Wed, Jan 28 - Sun, Feb 1
LATAM Airlines Logo
2:42 pm - 5:00 amDEN-LIM
12h 18m1 stop
LATAM Airlines Logo
12:15 pm - 10:50 pmLIM-DEN
12h 35m1 stop
$472LATAM Airlines
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Booking Insights

KAYAK's insights & trends for Denver to South America flights

Get data-powered insights and trends into flights from Denver to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Denver to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Denver to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Denver to South America is November, when tickets cost $508 (return) on average. On the other hand, the most expensive months are July and December, when the average cost of round-trip tickets is $811 and $719 respectively.

What’s the cheapest day of the week to fly from Denver to South America?

The average price of all round-trip flights from Denver to South America clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to South America on a Sunday, as we generally find the cheapest rates on that day for this route. On the other hand, Friday is the most expensive day to fly from Denver to South America. For your return ticket, we recommend flying on a Saturday and avoiding Mondays for the best deals.

How far in advance should I book a flight from Denver to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Denver to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Denver to South America, you should book around 2 weeks before departure, which saves you about 15% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 9 weeks before departure.

Good to know

Low seasonOctober
Cheapest flight$137
Best time to beat the crowds with an average 16% drop in price.
Most popular time to fly with an average 39% increase in price.
Flight from Denver to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Denver to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Denver to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Denver to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Denver to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Denver to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Denver to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Denver to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Denver to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the evening, when round-trip flights cost $549 on average. Morning departures are around 5% more expensive than evening flights, on average. The most expensive time of day to fly to South America is generally at night, which is peak travel time and where the average cost of a ticket is $643.

Reviews of the top 5 airlines serving from Denver to South America

 
Need help choosing which airline to fly with from Denver to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8000 reviews
7.9Entertainment
7.3Food
8.1Boarding
8.5Crew
7.9Comfort
Airline reviews

Great. Seamless. Check in agent at kiosk international was amazing and extremely helpful.

10.0 ExcellentWilliam, Nov 2025ATL - SJO
Read more Delta reviews

Great. Seamless. Check in agent at kiosk international was amazing and extremely helpful.

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

Service in business class was not impressive. I ordered coffee with dinner and then watched other people get 2 refills before I got my 1 cup of coffee, and only after I pressed the attendant button overhead. Furthermore, the seats in the forward cabin need maintenance on this 737-800: the upholstery is detaching from the seat frame, at least on the backs of seats 1C, 1D.

Plenty of leg room, temperature was great and staff was excellent. Would do it more often.

The ticket agents in West Palm Beach on Friday afternoon Nov. 7th were incredible in getting us on an earlier plane to Atlanta during the government shutdown. Had the taken our original flight we would have missed our connection. She did this on her own, We didn't even have to ask, and she did it all with a smile and showing genuine concern that we would be taken care of. We are very grateful and thankful. We fly often, and now we will be sure to fly Delta.

Flight delayed then cancelled. Misplaced luggage. Still do not have. Rented car 1100 mile drive. I had to buy some overnight Hotels clothes toiletries gas food at my expense. Still not home. Not sure where luggage is. Over 4 hours on hold to Felta

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

Everything went well and was good. Nothing exceptional, but no complaints either. Cheap seats are pretty comfortable.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

I selected first class expecting excetional service. It was mediocre at best. The food service was cold, meal choices was poor and on one leg they did provide dessert. I did enjoy the lay day seat but the movies were old and nothing current. Boarding the plane is always hot. So boarding is quite warm until your in the air. I took a small personal air fan. Update the meals and movies.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

Good flight, boarding ok and crew very nice. Flight was not full so I was able to be very comfortable. Blanket and pillow provided with was good as it was very cold during the flight . Food was very good(small snack sandwich and an excellent piece of orange cake). Overall good flight, no complaints.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

Lost ,y connection due to a mechanical delay, huge line to get new connection and vouchers

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

Great smooth flight. Had a seating change, but that was an improvement. Thanks United Airways Crew.

Flight was good but there are way to many announcements for credit cards etc.

Crew seemed a bit cranky. No seatback screens. But boarding was efficient and on time and we arrived early.

See previous note about the passenger in Denver who threw my husband's bag out of the overhead bin in order to maker room for his own. And the flight attendant back up the new passenger.

Terrible. They wouldn't allow me on my flight on the 14th..

Impressed with the service despite turbulence because of the weather. Both flights arrived before their scheduled times.

Great experience…left a bit behind schedule but made up fir that in the air and landed 10 minutes early 😁

The seat and leg room was not good. The food and beverage service was good.

For economy, it was very good. Staff was great, they even let some of us change seats for more leg room... Put an empty seat between us which was fantastic for a 12hr flight. Onboard entertainment was excellent, I think over 200 choices of movies/tv/etc The bad was the barely/nonfunctional wifi that cost either $16.99 or 1700 miles (full flight). It was atrocious... Definitely the worst of the last 3 long haul major airlines I was on the last few months.

Electric plugs didn't work. Entertainment system wasn't working

I had a positive experience on American. I'm blind and traveling with a guide dog and the flight attendants were so kind, friendly, and helpful towards us. They checked in on us during the flight and they made us feel comfortable and welcomed. There was an hour delay before depature, but overall the flight was a smooth ride. I appreciate that there were no issues on this long flight back home.

We were told the flight was delayed 5 times, then it was moved to the next day.

More choices on snacks. Built-in video screen to enjoy entertainment choices.

we landed at cmh ten minutes early but had to sit on tarmac for twenty minutes because a plane was at our gate despite the fact that 3 other gates were open.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

I have a gluten allergy so did have any food

I have a gluten allergy so didn't have any food

Loved the crew . Absolutely no complaints. Except for luggage lost

Everything was good The connects, with no blame to crew. Or pilots. I understand they are short staffed. Everything went well for me. I'll be using you guys again in May if not sooner.

this plane was really old, had exit row seats and tray was in arm of seat so super uncomfortable to use. another seat they could t even use the tray it was broke. seat i. front of me had duct tape on it cause seat was ripped open... this plane should either be updated or retired.

Everything you need to know for your flight to South America

Information on your arrival and departure airports