$133 Find Cheap Flights from Denver to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to South America departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South America

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Free to useThere are no hidden charges or fees.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Denver to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$446
Bogotá
Bogotá1 stop$360
Sao Paulo
Sao Paulo1 stop$700
Rio de Janeiro
Rio de Janeiro1 stop$797
Santiago
Santiago2 stops$562
Cartagena
Cartagena1 stop$407
Quito
Quito1 stop$422
Guayaquil
Guayaquil1 stop$403
Cali
Cali1 stop$477
Cusco
Cusco2 stops$599
Georgetown
Georgetown1 stop$494
Pereira
Pereira2 stops$459
Montevideo
Montevideo2 stops$1,083
Barranquilla
Barranquilla1 stop$425
Santa Marta
Santa Marta2 stops$464
Lima
Lima1 stop$446
Bogotá
Bogotá1 stop$360
Sao Paulo
Sao Paulo1 stop$700
Rio de Janeiro
Rio de Janeiro1 stop$797
Santiago
Santiago2 stops$562
Cartagena
Cartagena1 stop$407
Quito
Quito1 stop$422
Guayaquil
Guayaquil1 stop$403
Cali
Cali1 stop$477
Cusco
Cusco2 stops$599
Georgetown
Georgetown1 stop$494
Pereira
Pereira2 stops$459
Montevideo
Montevideo2 stops$1,083
Barranquilla
Barranquilla1 stop$425
Santa Marta
Santa Marta2 stops$464

Book Cheap Denver to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to South America

Thu, Apr 9 - Tue, Apr 14
Multiple Airlines Logo
11:59 pm - 11:55 am
DEN
-
BOG
10h 56m
1 stop
Multiple Airlines Logo
12:50 pm - 10:59 pm
BOG
-
DEN
11h 09m
1 stop
$360Multiple Airlines
Wed, Apr 8 - Tue, Apr 14
Multiple Airlines Logo
11:59 pm - 11:55 am
DEN
-
BOG
10h 56m
1 stop
Multiple Airlines Logo
12:50 pm - 10:59 pm
BOG
-
DEN
11h 09m
1 stop
$361Multiple Airlines
Sun, Apr 26 - Fri, May 1
United Airlines Logo
5:00 am - 7:20 pm
DEN
-
BOG
13h 20m
1 stop
United Airlines Logo
8:30 am - 11:58 pm
BOG
-
DEN
16h 28m
1 stop
$367United Airlines
Sun, Apr 26 - Fri, May 1
United Airlines Logo
5:00 am - 7:20 pm
DEN
-
BOG
13h 20m
1 stop
United Airlines Logo
8:30 am - 11:58 pm
BOG
-
DEN
16h 28m
1 stop
$369United Airlines
Wed, Aug 12 - Tue, Aug 18
American Airlines Logo
8:20 am - 10:30 pm
DEN
-
BOG
13h 10m
1 stop
American Airlines Logo
12:25 pm - 11:41 pm
BOG
-
DEN
12h 16m
2 stops
$380American Airlines
Mon, Mar 9 - Fri, Mar 13
American Airlines Logo
7:01 am - 10:10 pm
DEN
-
BOG
14h 09m
1 stop
American Airlines Logo
11:55 pm - 8:31 pm
BOG
-
DEN
21h 36m
1 stop
$382American Airlines
Mon, Apr 6 - Fri, Apr 17
Copa Airlines Logo
10:51 pm - 8:40 am
DEN
-
CTG
8h 49m
1 stop
Copa Airlines Logo
9:45 am - 6:25 pm
CTG
-
DEN
9h 40m
1 stop
$407Copa Airlines
Wed, Apr 15 - Wed, Apr 22
Copa Airlines Logo
10:51 pm - 12:25 pm
DEN
-
LIM
12h 34m
1 stop
Copa Airlines Logo
4:00 am - 6:25 pm
LIM
-
DEN
15h 25m
1 stop
$446Copa Airlines
Wed, Apr 8 - Wed, Apr 15
Delta Logo
6:10 am - 4:43 am
DEN
-
UIO
21h 33m
2 stops
Delta Logo
6:50 pm - 1:32 pm
UIO
-
DEN
19h 42m
2 stops
$459Delta
Mon, Mar 9 - Fri, Mar 13
Delta Logo
12:55 am - 1:15 pm
DEN
-
CTG
11h 20m
1 stop
Delta Logo
2:30 pm - 12:09 am
CTG
-
DEN
10h 39m
1 stop
$479Delta
Booking Insights

KAYAK's insights & trends for Denver to South America flights

Get data-powered insights and trends into flights from Denver to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Denver to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Denver to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Denver to South America is November, when tickets cost $504 (return) on average. On the other hand, the most expensive months are July and December, when the average cost of round-trip tickets is $825 and $688 respectively.

How far in advance should I book a flight from Denver to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Denver to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Denver to South America, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Good to know

Low seasonOctober
Cheapest flight$133
Best time to beat the crowds with an average 13% drop in price.
Most popular time to fly with an average 25% increase in price.
Flight from Denver to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Denver to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Denver to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Denver to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Denver to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Denver to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Denver to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Denver to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Denver to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Denver to South America

 
Need help choosing which airline to fly with from Denver to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8245 reviews
8.5Crew
8.1Boarding
7.9Comfort
7.8Entertainment
7.2Food
Airline reviews

Everything was good except wifi and a leaking drink chiller. The floor was all wet and my bag was soaked. Did not notice until debarking. Have not heard back from Delta. Even though this was leg one of an international flight in first class, they denied access to their Sky Club - very disappointing!

6.0 GoodAnonymous, Feb 2026
RDU - SEA
Read more Delta reviews

Everything was good except wifi and a leaking drink chiller. The floor was all wet and my bag was soaked. Did not notice until debarking. Have not heard back from Delta. Even though this was leg one of an international flight in first class, they denied access to their Sky Club - very disappointing!

The staff was fine. The plane was extremely tight, and I paid for the wifi and it did not work at all. I was actually going to ask for a refund.

two hour delay and the Delta representative on the PA system was unable to understand

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

2+hrs delay without any reason provided and a cramped flight

We waited an hour on the runway to get a gate in Orlando

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

Flight was delayed due to crew being not on time

Flight crew issues delayed my flight by 2 1/2 hours. Causing me to miss my connection.

The staff on board and gate was nice - a welcome change from the usual. We also arrived early, which was a great benefit, given that it takes 30 minutes plus to get bags at SRQ.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

On board crew was very good. Crew was friendly, snacks were good, especially the chips. Seats seemed a bit cramped. Boarding seemed unorganized, as we were instructed to get to the gate an hour early and then just stood around until boarding.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

The flight was late. Please do not delay next time.

Flight got delayed; had to go through security three times.

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

Flight left on time and we arrived 25 minutes early! There was a gate available when we arrived so early on a busy Sunday afternoon! Flight attendants came around twice with the drinks cart.

Sitting on the runway after we land for almost two hours! Not sure if we should blame United or Just Dumpy Vance.

Flight was late - I was downgraded from first class to coach

United overall experience is great these days. Airport experience was very organized. Staff on flight were great. App and information as good as it gets.

Great smooth flight. Had a seating change, but that was an improvement. Thanks United Airways Crew.

Flight was good but there are way to many announcements for credit cards etc.

Crew seemed a bit cranky. No seatback screens. But boarding was efficient and on time and we arrived early.

See previous note about the passenger in Denver who threw my husband's bag out of the overhead bin in order to maker room for his own. And the flight attendant back up the new passenger.

Terrible. They wouldn't allow me on my flight on the 14th..

Impressed with the service despite turbulence because of the weather. Both flights arrived before their scheduled times.

For my arriving destination, we were delayed multiple times to the point that we arrived 6 hours after we were originally scheduled. On my flight home, they overbooked and involuntarily removed passengers (including me) from the plane. It was not a good experience.

It was good experience this time. The flight was on time.

I very rarely fly American and my experience today reenforces that is the correct decision. While the staff were all very courteous, our flight was first thing in the morning so there was no reason to be delayed, yet appropriate maintenance checks weren’t completed prior to our flight so we were delayed multiple times. Not a great showing, American Airlines.

It's very confusing because Kayak has it as American Airlines, but it was Hawaiian Airlines, but operated by Alaska Airlines. I had to go to the airport for my boarding pass because American said I didn't have any trips.

Smooth flight. From the early boarding and all were on board before departure time and arrived early in ONT. Great crew. Thank you!!!!

Small plane, poor meal choices for first class, bad terminal and boarding experience at LAX

Lack of gluten free options in food service. I have Celiac disease and it appears you no longer offer special meals for people with dietary restrictions. I am a frequent flyer traveling into and out of Omaha airport. I have noticed over the course of several months that although our flight typically arrives ahead of schedule (awesome job AA!) - we typically sit on the runway for several minutes waiting for the ground crew to get in place. Not sure if it is a ground crew issue or a gate availability issue (due to construction at this airport). Seems to be more of a ground crew being on time issue.

Arrived early picked up my bag in a few minutes- great trip - thank you

Flight boarded, departed and landed on time. Excellent service from flight attendant in FIRST

Boarding is always an ordeal. Less dogs on flights. I am highly allergic to dogs and cats. Why are there so many animals these days?

Everything you need to know for your flight to South America

Information on your arrival and departure airports