$177 Find Cheap Flights from Denver to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to South America departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South America

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Free to useThere are no hidden charges or fees.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Denver to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$539
Bogotá
Bogotá1 stop$404
Sao Paulo
Sao Paulo2 stops$780
Rio de Janeiro
Rio de Janeiro1 stop$802
Santiago
Santiago1 stop$568
Cartagena
Cartagena1 stop$455
Quito
Quito1 stop$473
Guayaquil
Guayaquil1 stop$473
Cali
Cali1 stop$438
Cusco
Cusco2 stops$842
Georgetown
Georgetown2 stops$554
Pereira
Pereira2 stops$568
Barranquilla
Barranquilla2 stops$526
Montevideo
Montevideo2 stops$1,186
Santa Marta
Santa Marta2 stops$699
Lima
Lima1 stop$539
Bogotá
Bogotá1 stop$404
Sao Paulo
Sao Paulo2 stops$780
Rio de Janeiro
Rio de Janeiro1 stop$802
Santiago
Santiago1 stop$568
Cartagena
Cartagena1 stop$455
Quito
Quito1 stop$473
Guayaquil
Guayaquil1 stop$473
Cali
Cali1 stop$438
Cusco
Cusco2 stops$842
Georgetown
Georgetown2 stops$554
Pereira
Pereira2 stops$568
Barranquilla
Barranquilla2 stops$526
Montevideo
Montevideo2 stops$1,186
Santa Marta
Santa Marta2 stops$699

Book Cheap Denver to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to South America

Fri, May 29 - Wed, Jun 3
Multiple Airlines Logo
6:00 am - 10:00 pm
DEN
-
BOG
15h 00m
1 stop
Multiple Airlines Logo
7:20 am - 11:28 pm
BOG
-
DEN
17h 08m
1 stop
$404Multiple Airlines
Fri, May 29 - Sun, Jun 7
United Airlines Logo
6:00 am - 10:00 pm
DEN
-
BOG
15h 00m
1 stop
United Airlines Logo
8:30 am - 11:57 pm
BOG
-
DEN
16h 27m
1 stop
$405United Airlines
Sun, May 31 - Thu, Jun 4
Delta Logo
12:56 am - 8:10 pm
DEN
-
BOG
18h 14m
2 stops
Delta Logo
2:55 pm - 8:44 am
BOG
-
DEN
18h 49m
1 stop
$410Delta
Mon, Jun 1 - Wed, Jun 3
American Airlines Logo
5:00 am - 10:38 pm
DEN
-
BOG
16h 38m
1 stop
American Airlines Logo
12:15 am - 7:36 pm
BOG
-
DEN
20h 21m
1 stop
$412American Airlines
Mon, Jun 1 - Sun, Jun 7
Delta Logo
4:41 pm - 7:15 pm
DEN
-
BOG
25h 34m
1 stop
Delta Logo
2:55 pm - 12:22 am
BOG
-
DEN
10h 27m
1 stop
$414Delta
Thu, May 28 - Tue, Jun 2
American Airlines Logo
12:39 pm - 10:38 pm
DEN
-
BOG
8h 59m
1 stop
American Airlines Logo
6:30 am - 11:55 pm
BOG
-
DEN
18h 25m
2 stops
$420American Airlines
Wed, Nov 11 - Thu, Nov 19
Copa Airlines Logo
9:38 pm - 2:10 pm
DEN
-
UIO
14h 32m
1 stop
Copa Airlines Logo
3:09 am - 5:16 pm
UIO
-
DEN
16h 07m
1 stop
$473Copa Airlines
Mon, Sep 14 - Wed, Sep 23
Copa Airlines Logo
10:43 pm - 2:07 pm
DEN
-
UIO
14h 24m
1 stop
Copa Airlines Logo
3:09 pm - 6:11 pm
UIO
-
DEN
28h 02m
1 stop
$488Copa Airlines
Mon, Sep 14 - Wed, Sep 23
LATAM Airlines Logo
4:40 pm - 11:00 pm
DEN
-
UIO
29h 20m
2 stops
LATAM Airlines Logo
9:00 am - 11:45 pm
UIO
-
DEN
15h 45m
2 stops
$499LATAM Airlines
Sun, Jun 7 - Mon, Jun 15
LATAM Airlines Logo
12:40 am - 8:05 am
DEN
-
LIM
30h 25m
2 stops
LATAM Airlines Logo
12:05 am - 5:53 pm
LIM
-
DEN
18h 48m
1 stop
$555LATAM Airlines
Booking Insights

KAYAK's insights & trends for Denver to South America flights

Get data-powered insights and trends into flights from Denver to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Denver to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Denver to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Denver to South America is September, when tickets cost $74 (return) on average. On the other hand, the most expensive months are January and June, when the average cost of round-trip tickets is $1,638 and $1,279 respectively.

How far in advance should I book a flight from Denver to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Denver to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Denver to South America, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 9 weeks before departure.

Good to know

Low seasonOctober
Cheapest flight$177
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 23% increase in price.
Flight from Denver to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Denver to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Denver to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Denver to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Denver to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Denver to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Denver to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Denver to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Denver to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Denver to South America

 
Need help choosing which airline to fly with from Denver to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8452 reviews
8.5Crew
7.2Food
8.1Boarding
7.8Entertainment
7.8Comfort
Airline reviews

Was revoked with Jet Blue due to delay from Kenya Air

4.0 OkayTim, May 2026
JFK - JAX
Read more Delta reviews

Was revoked with Jet Blue due to delay from Kenya Air

The Boarding process was great. Particularly since my wife and I require assistance. The flight attendants were amazing. We travel frequently; they honestly were a cut above. 😀

Enjoyed it very much. Especially liked the free WiFi that Delta offers.

Smooth flight. Left on time, and got in 15 minutes early. Onboard video was great

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

WiFi didn’t work on two of four planes. Flight attendants were not overly friendly or welcoming. Planes were extremely slow to board and deplane.

Delta does a great job with entertainment and free wifi. I can still be in touch with my colleagues while in the air.

Aside from a completely packed plane, I really have no complaints.

Bus to plane was delayed for no apparent reason and our luggage was still on the belt when they shut it off. Took about 20 minutes to turn it back on to get our luggage.

It was a pleasant surprise to have complimentary Wi-Fi on the flight

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

Flight got delayed; had to go through security three times.

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

In flight from Miami to Anchorage, we were all on board ready to take off. Pilot decided to take on more fuel causing a delay. Once fueled, the pilot came back over the radio stating more delay due to VIP. These delays caused me to miss my connecting flight. I went to the Alaska Air counter for information. They flat out stated that it was ATCs fault that I missed my flight and booked me a flight the next day about 1300 . I believe if we had the fuel prior to getting on board we would not of been delayed and I would have taken off on time. Pilot was taken out of the equation. I think they should’ve taken responsibility for their pilots decision to top off his aircraft instead of waiting til the last moment. Enough said…

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Nothing I like, I missed this connection b/c of an earlier flight delay. I had to stay one more night and I paid out my own pocket. LATAM failed to send me to a safe and decent hotel.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

On board crew was very good. Crew was friendly, snacks were good, especially the chips. Seats seemed a bit cramped. Boarding seemed unorganized, as we were instructed to get to the gate an hour early and then just stood around until boarding.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

O’hsre taxi and deboarding took 40 minutes. Needed 20 minutes extra time between connecting flights to avoid running through terminal.

Was great in general, try to respect time and excuses when slight changes have been made, appreciated!

Really hard landing... as in slammed into the runway then hit the brakes really hard ...

Putting people that close to the bathroom, where you have to look into the bathroom as people are exiting and entering was not great and the smell was also not great. I know the airlines are desperate for more chairs, but that seat is a crime.

Every staff member was professional, friendly and courteous. The pizza twist was ok. It was warm but too much dough.

one staffer was frustrated (it happen); the flight was late and the pilot mentioned they'll make amend but the snacks were the same, other than that the aircraft was clean and everything went smooth, no complaints

Wonderful in-seat entertainment with seatback screens and huge selection of quality movies. The ability to bluetooth connect headphones was amazing.

No seat back entertainment. And app had a hard time getting entertainment loaded.

ticket agent lady wás very helpful , she arranged wheel chair for my elderly mother

Flight left on time and we arrived 25 minutes early! There was a gate available when we arrived so early on a busy Sunday afternoon! Flight attendants came around twice with the drinks cart.

The wifi experience is awful. I had to try again and again, taking over 30 minutes, to connect to the wifi. I had to watch the same two ads over and over until I was finally successful. Once connected, it was anything but "high speed" and disconnected at least three times during the flight.

Fine. Nothing to write home about. The plane left on time, and arrived on time.

I was downgraded from first class to coach due to an airplane change. They pulled me out of line and I was the very last person to board the plane stuck in the middle seat with no overhead place to put my carry-.on. Very poor customer service.

Seat comfort was poor (no lumbar or lower back support).

The airplane seats were spacious and comfortable, and the flight attendants were friendly and attentive. The food was delicious like never before. The blankets and toiletries were thoughtfully provided. The captain's navigation was steady and reliable. In short, having flown with Starlux, I won't consider any other airline next time.

STOP MAKING THE SEATING SO CRAMPED. WE NEED A PASSENGER BILL OF RIGHTS!

The passenger in front of of me reclined their seat back all the way the entire flight. Their headrest was in my face the entire flight! I barely had room for the little plastic cup of water to fit on my tray table; can you make the seats and space between the rows any smaller??? You can’t even get up to use the restroom! Worst flight I’ve had in a very long time!

We had several flights and they were all on-time and flawless

My Frequent Flyer nber wasn't put on as I was told it was..... This resulted in a last group boarding and no priority tags on My bags.

Premium Economy Good crew, good service, excellent food. Seat back screen just not bright enough.

Everything you need to know for your flight to South America

Information on your arrival and departure airports