$137 Find Cheap Flights from Denver to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to South America departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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1 adult, Economy, 0 bags

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Cheap Flights from Denver to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$453
Bogotá
Bogotá1 stop$343
Sao Paulo
Sao Paulo2 stops$560
Rio de Janeiro
Rio de Janeiro1 stop$808
Santiago
Santiago1 stop$538
Cartagena
Cartagena2 stops$331
Quito
Quito1 stop$388
Guayaquil
Guayaquil1 stop$379
Cali
Cali1 stop$347
Cusco
Cusco2 stops$602
Pereira
Pereira1 stop$394
Georgetown
Georgetown1 stop$469
Montevideo
Montevideo1 stop$790
Barranquilla
Barranquilla2 stops$408
Santa Marta
Santa Marta2 stops$577
Florianopolis
Florianopolis2 stops$1,108
Lima
Lima1 stop$453
Bogotá
Bogotá1 stop$343
Sao Paulo
Sao Paulo2 stops$560
Rio de Janeiro
Rio de Janeiro1 stop$808
Santiago
Santiago1 stop$538
Cartagena
Cartagena2 stops$331
Quito
Quito1 stop$388
Guayaquil
Guayaquil1 stop$379
Cali
Cali1 stop$347
Cusco
Cusco2 stops$602
Pereira
Pereira1 stop$394
Georgetown
Georgetown1 stop$469
Montevideo
Montevideo1 stop$790
Barranquilla
Barranquilla2 stops$408
Santa Marta
Santa Marta2 stops$577
Florianopolis
Florianopolis2 stops$1,108

Book Cheap Denver to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to South America

Sat, Jan 24 - Tue, Feb 10
Multiple Airlines Logo
4:50 pm - 11:03 amDEN-MDE
16h 13m1 stop
Multiple Airlines Logo
2:54 pm - 3:55 pmMDE-DEN
27h 01m1 stop
$340Multiple Airlines
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Thu, Nov 6 - Sun, Nov 9
United Airlines Logo
5:00 am - 10:35 pmDEN-BOG
15h 35m1 stop
United Airlines Logo
1:30 am - 10:05 amBOG-DEN
10h 35m1 stop
$343United Airlines
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Thu, Nov 13 - Thu, Nov 27
Copa Airlines Logo
9:38 pm - 10:10 amDEN-BOG
10h 32m1 stop
Copa Airlines Logo
6:10 am - 5:17 pmBOG-DEN
13h 07m1 stop
$346Copa Airlines
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Tue, Nov 4 - Tue, Nov 18
American Airlines Logo
6:23 am - 10:10 pmDEN-BOG
13h 47m2 stops
American Airlines Logo
8:00 am - 11:17 pmBOG-DEN
17h 17m1 stop
$348American Airlines
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Thu, Nov 6 - Mon, Nov 10
American Airlines Logo
9:11 am - 11:30 pmDEN-BOG
12h 19m1 stop
American Airlines Logo
3:15 pm - 12:01 pmBOG-DEN
22h 46m1 stop
$352American Airlines
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Tue, Dec 2 - Tue, Dec 9
Copa Airlines Logo
9:36 pm - 1:29 pmDEN-BOG
13h 53m1 stop
Copa Airlines Logo
7:00 am - 5:17 pmBOG-DEN
12h 17m1 stop
$361Copa Airlines
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Mon, Nov 17 - Thu, Dec 4
Delta Logo
12:50 am - 7:30 pmDEN-BOG
16h 40m1 stop
Delta Logo
9:00 am - 8:30 pmBOG-DEN
13h 30m1 stop
$403Delta
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Mon, Mar 9 - Wed, Mar 11
LATAM Airlines Logo
12:59 am - 2:33 pmDEN-BOG
12h 34m1 stop
LATAM Airlines Logo
7:00 am - 11:54 pmBOG-DEN
17h 54m2 stops
$408LATAM Airlines
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Fri, Nov 7 - Wed, Nov 12
Delta Logo
4:47 pm - 7:30 pmDEN-BOG
24h 43m1 stop
Delta Logo
7:00 am - 7:31 pmBOG-DEN
14h 31m2 stops
$413Delta
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Thu, Jan 22 - Mon, Jan 26
LATAM Airlines Logo
12:59 am - 8:20 pmDEN-BOG
17h 21m2 stops
LATAM Airlines Logo
3:55 pm - 12:04 pmBOG-DEN
22h 09m1 stop
$441LATAM Airlines
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Booking Insights

KAYAK's insights & trends for Denver to South America flights

Get data-powered insights and trends into flights from Denver to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Denver to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Denver to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Denver to South America is November, when tickets cost $535 (return) on average. On the other hand, the most expensive months are July and December, when the average cost of round-trip tickets is $801 and $720 respectively.

What’s the cheapest day of the week to fly from Denver to South America?

The average price of all round-trip flights from Denver to South America clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to South America on a Sunday, as we generally find the cheapest rates on that day for this route. On the other hand, Friday is the most expensive day to fly from Denver to South America. For your return ticket, we recommend flying on a Saturday and avoiding Mondays for the best deals.

How far in advance should I book a flight from Denver to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Denver to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Denver to South America, you should book around 2 weeks before departure, which saves you about 19% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 2 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$119
Best time to beat the crowds with an average 13% drop in price.
Most popular time to fly with an average 42% increase in price.
Flight from Denver to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Denver to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Denver to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Denver to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Denver to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Denver to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Denver to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Denver to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Denver to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the evening, when round-trip flights cost $549 on average. Morning departures are around 5% more expensive than evening flights, on average. The most expensive time of day to fly to South America is generally at night, which is peak travel time and where the average cost of a ticket is $643.

Reviews of the top 5 airlines serving from Denver to South America

 
Need help choosing which airline to fly with from Denver to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7981 reviews
7.9Entertainment
7.9Comfort
8.2Boarding
7.3Food
8.5Crew
Airline reviews

The aircraft interior is old and tired on this aircraft. The entertainment system never worked despite the crews attempt to reset the system.

6.0 GoodDavid, Oct 2025JFK - KEF
Read more Delta reviews

The aircraft interior is old and tired on this aircraft. The entertainment system never worked despite the crews attempt to reset the system.

The flight used a B767 with a very old interior from before 2014. The entertainment system did not work at all during the flight despite attempts to reset the system. It was like they flew this route just to be competitive.

Old plane and old configuration/seats but still comfortable for a morning flight

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

Flight was too crowded and seats are too small, especially since passengrs are getting larger. Having a middle seat is ALWAYS tough! Woman on my left was large & kept creeping in to my space. Flight personnel were great! Have more savory rather than sweet snacks please.

Flight was crowded and the woman sitting on my left was large & kept crouching in to my space. You need bigger seats or smaller passengers to fit into the seats you DO have! Snack were OK. Would appreciate if airlines had more savory rather than sweet snacks, thank you!

Delayed flight (1hour) plus a long layover after an overnight flight with no backup plane available.

We were delayed, which I think had to do with air traffic control. Otherwise, everything was great.

The boarding process needs to be refined. Sometimes the gate crew calls out the zones and then flip to showing the.zones boarding on the gate monitor display. So, unless you are huddled around the gate lanes watching the monitor, you could miss your boarding zone. Suggest the zones be announced each time a new zone is allowed to board.

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

I selected first class expecting excetional service. It was mediocre at best. The food service was cold, meal choices was poor and on one leg they did provide dessert. I did enjoy the lay day seat but the movies were old and nothing current. Boarding the plane is always hot. So boarding is quite warm until your in the air. I took a small personal air fan. Update the meals and movies.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

Tell people to remain in their seats during the meal/beverage distribution. Enforce boarding by group numbers. No one was checking. Tell people to turn their electronics speakers off. Bigger cups for drinks.

Poor, the airline was not able to help me move flights.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

Lost ,y connection due to a mechanical delay, huge line to get new connection and vouchers

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

Great smooth flight. Had a seating change, but that was an improvement. Thanks United Airways Crew.

Flight was good but there are way to many announcements for credit cards etc.

Crew seemed a bit cranky. No seatback screens. But boarding was efficient and on time and we arrived early.

See previous note about the passenger in Denver who threw my husband's bag out of the overhead bin in order to maker room for his own. And the flight attendant back up the new passenger.

Terrible. They wouldn't allow me on my flight on the 14th..

Impressed with the service despite turbulence because of the weather. Both flights arrived before their scheduled times.

Great experience…left a bit behind schedule but made up fir that in the air and landed 10 minutes early 😁

The seat and leg room was not good. The food and beverage service was good.

For economy, it was very good. Staff was great, they even let some of us change seats for more leg room... Put an empty seat between us which was fantastic for a 12hr flight. Onboard entertainment was excellent, I think over 200 choices of movies/tv/etc The bad was the barely/nonfunctional wifi that cost either $16.99 or 1700 miles (full flight). It was atrocious... Definitely the worst of the last 3 long haul major airlines I was on the last few months.

Electric plugs didn't work. Entertainment system wasn't working

The only thing to like was that we eventually got to our destination

Delayed delayed delayed and no offer for food or vouchers

Disliked having to wait a little longer to disembark from the plan when we landed in London

Typically flights with AA are good. The staff are pleasant, welcoming, and efficient.

A couple ladies from the crew were so rude and nasty. Thought they were mad at having to be there especially if you asked a question. This will make me think twice next time if I book a flight with you.

Delays to take off and to leave the plane after landing added a lot of time to this flight.

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

Always seated jammed in rear of aircraft Admirals Club food at DFW terminal D was absolute worst food experience and I pay $600/year to eat this dried out junk

Flight was delayed because of a bird strike. They had another plane available within 45 minutes.

Mostly good. Flight was crowded but Airline personnel were very friendly & accommodating. It would be good to have savory snacks rather than just sweet Biscoff cookies.

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