$134 Find Cheap Flights from Denver to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to South America departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Denver to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$458
Bogotá
Bogotá2 stops$392
Sao Paulo
Sao Paulo2 stops$668
Rio de Janeiro
Rio de Janeiro2 stops$797
Santiago
Santiago2 stops$552
Cartagena
Cartagena1 stop$325
Quito
Quito1 stop$400
Guayaquil
Guayaquil2 stops$347
Cali
Cali2 stops$423
Cusco
Cusco2 stops$664
Georgetown
Georgetown2 stops$484
Pereira
Pereira1 stop$415
Montevideo
Montevideo1 stop$929
Barranquilla
Barranquilla1 stop$421
Santa Marta
Santa Marta2 stops$507
Lima
Lima1 stop$458
Bogotá
Bogotá2 stops$392
Sao Paulo
Sao Paulo2 stops$668
Rio de Janeiro
Rio de Janeiro2 stops$797
Santiago
Santiago2 stops$552
Cartagena
Cartagena1 stop$325
Quito
Quito1 stop$400
Guayaquil
Guayaquil2 stops$347
Cali
Cali2 stops$423
Cusco
Cusco2 stops$664
Georgetown
Georgetown2 stops$484
Pereira
Pereira1 stop$415
Montevideo
Montevideo1 stop$929
Barranquilla
Barranquilla1 stop$421
Santa Marta
Santa Marta2 stops$507

Book Cheap Denver to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to South America

Mon, Feb 23 - Sat, Mar 7
Copa Airlines Logo
9:38 pm - 8:41 am
DEN
-
CTG
9h 03m
1 stop
Copa Airlines Logo
9:42 am - 5:16 pm
CTG
-
DEN
9h 34m
1 stop
$325Copa Airlines
Sat, Feb 28 - Wed, Mar 11
American Airlines Logo
11:31 pm - 3:30 pm
DEN
-
CTG
13h 59m
1 stop
American Airlines Logo
3:15 pm - 8:20 am
CTG
-
DEN
18h 05m
2 stops
$329American Airlines
Tue, Feb 24 - Fri, Mar 6
American Airlines Logo
5:57 pm - 3:30 pm
DEN
-
CTG
19h 33m
2 stops
American Airlines Logo
4:30 pm - 8:20 am
CTG
-
DEN
17h 50m
2 stops
$342American Airlines
Sat, Feb 28 - Wed, Mar 11
Copa Airlines Logo
9:38 pm - 8:41 am
DEN
-
CTG
9h 03m
1 stop
Copa Airlines Logo
9:42 am - 6:16 pm
CTG
-
DEN
9h 34m
1 stop
$366Copa Airlines
Fri, Feb 13 - Sat, Feb 21
LATAM Airlines Logo
12:59 am - 2:25 pm
DEN
-
BOG
11h 26m
1 stop
LATAM Airlines Logo
3:55 pm - 12:23 am
BOG
-
DEN
10h 28m
1 stop
$404LATAM Airlines
Wed, Feb 11 - Mon, Feb 16
Delta Logo
7:05 am - 7:30 pm
DEN
-
BOG
10h 25m
1 stop
Delta Logo
3:55 pm - 12:23 am
BOG
-
DEN
10h 28m
1 stop
$405Delta
Wed, Mar 4 - Sun, Mar 8
Delta Logo
12:59 am - 8:20 pm
DEN
-
BOG
17h 21m
2 stops
Delta Logo
3:55 pm - 9:26 am
BOG
-
DEN
18h 31m
1 stop
$410Delta
Thu, Mar 12 - Sun, Mar 22
United Airlines Logo
5:00 am - 10:35 pm
DEN
-
BOG
16h 35m
1 stop
United Airlines Logo
8:15 am - 6:40 am
BOG
-
DEN
23h 25m
1 stop
$413United Airlines
Fri, Feb 13 - Sun, Feb 22
United Airlines Logo
7:45 am - 10:35 pm
DEN
-
BOG
12h 50m
1 stop
United Airlines Logo
8:15 am - 11:35 pm
BOG
-
DEN
17h 20m
1 stop
$415United Airlines
Tue, Mar 3 - Tue, Mar 10
LATAM Airlines Logo
2:45 pm - 5:00 am
DEN
-
LIM
12h 15m
1 stop
LATAM Airlines Logo
12:15 pm - 12:09 am
LIM
-
DEN
12h 54m
1 stop
$458LATAM Airlines
Booking Insights

KAYAK's insights & trends for Denver to South America flights

Get data-powered insights and trends into flights from Denver to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Denver to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Denver to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Denver to South America is November, when tickets cost $504 (return) on average. On the other hand, the most expensive months are July and December, when the average cost of round-trip tickets is $808 and $687 respectively.

How far in advance should I book a flight from Denver to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Denver to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Denver to South America, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 9 weeks before departure.

Good to know

Low seasonOctober
Cheapest flight$134
Best time to beat the crowds with an average 13% drop in price.
Most popular time to fly with an average 21% increase in price.
Flight from Denver to Lima

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Denver to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Denver to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Denver to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Denver to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Denver to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Denver to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Denver to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Denver to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Denver to South America

 
Need help choosing which airline to fly with from Denver to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8075 reviews
8.5Crew
7.8Entertainment
7.2Food
8.1Boarding
7.9Comfort
Airline reviews

Probably not the fault of Delta but there was delay after delay after delay and I ended up getting home 4 hours later then I should have at 1:30 in the morning

4.0 Okaybyron, Jan 2026
CWA - MSP
Read more Delta reviews

Probably not the fault of Delta but there was delay after delay after delay and I ended up getting home 4 hours later then I should have at 1:30 in the morning

Easiest airport experience ever in my life at MSP with Delta check-in and flight attendant gave us a bottle of champagne in celebration of our 10-year wedding anniversary, so overall amazing!

No in flight service, no explanation - FC got service, C+ did not, unsure about Economy. No turbulence to speak of, so I guess another way to cut cost, or promote health and well being of Delta employees? Also, boarding in MEM combined zones, and with overhead space already full on both flights after Zone 2/ Diamond, presents a huge challenge to find a space for a bag. Delta, other than point A to B, is no longer reasonable to fly - very poor experiences, not even taking into account the chastising at the gate and rude crews, across the board.

It would have been better if the flight wasn't delayed by 2.5 hours

Delta’s staff is unmatched. From the gate agents, to the pilots, to the flight attendants… all top of the industry.

Delta flight Delay for ,more that two hours i.e original flight was 6.30 PM and it starts at 8.45 PM, When we connect Delta team for meal vouchers as it is late arrival in designation,But we did not get it as per delta policy , which is not good for mid night arrival,

Inexperienced boarding crew allowed too many bags on to a full flight and delayed takeoff causing a missed connection and unplanned overnight stay. There was a hotel at the airport but Delta would not pay for it offering only to shuttle me to an area hotel. Never even offerred so much as an apology by anyone working for Delta.

Staff was great! Kind and cordial! Middle seat row 28 seat B has a hump in it. Trays were getting stuck when putting down and up. Good flight

Departure was delayed resulting in me missing my connection. Delta did not autimatically find me another flight.

The seats weren’t reclining even though it wasn’t as exit seat

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

I selected first class expecting excetional service. It was mediocre at best. The food service was cold, meal choices was poor and on one leg they did provide dessert. I did enjoy the lay day seat but the movies were old and nothing current. Boarding the plane is always hot. So boarding is quite warm until your in the air. I took a small personal air fan. Update the meals and movies.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

Sitting on the runway after we land for almost two hours! Not sure if we should blame United or Just Dumpy Vance.

Flight was late - I was downgraded from first class to coach

United overall experience is great these days. Airport experience was very organized. Staff on flight were great. App and information as good as it gets.

Great smooth flight. Had a seating change, but that was an improvement. Thanks United Airways Crew.

Flight was good but there are way to many announcements for credit cards etc.

Crew seemed a bit cranky. No seatback screens. But boarding was efficient and on time and we arrived early.

See previous note about the passenger in Denver who threw my husband's bag out of the overhead bin in order to maker room for his own. And the flight attendant back up the new passenger.

Terrible. They wouldn't allow me on my flight on the 14th..

Impressed with the service despite turbulence because of the weather. Both flights arrived before their scheduled times.

Great experience…left a bit behind schedule but made up fir that in the air and landed 10 minutes early 😁

Crew in Columbia was not prepared for landing. It was a bit of a disaster and getting bags took forever.

My seat tv didn’t work the whole trip. And the seat space is too small despite being seated at the front.

The seat cushions were very worn so they were extremely uncomfortable.

Delayed, no updates, had a rewards number but was not working

The seats from lax to DFW was so tight that I could not move my legs . No WiFi and had to pay . Not a good selection of entertainment

AA should improve their in air internet & entertainment options. Seems unreasonable to charge $20/hr and should have some form of free connections. The entertainment options are also pretty limited, movies are outdated and the series only show 3-5 episodes.

The professionals have excellent customer service, the seats don´t have enough space.

We were upgraded to First Class and it was a great flight

Amazing I love American. I’ll never fly anyone else if I can help it.

I love American. I’ll never fly anyone else if I can help it.

Everything you need to know for your flight to South America

Information on your arrival and departure airports