$122 Find Cheap Flights from Denver to South Carolina - Compare and Save

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Cheap Flights from Denver to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Sort by: Cheapest
Charleston
3h 05mNonstop
from $259per person
Greenville
3h 02mNonstop
from $276per person
Myrtle Beach
4h 43m2 stops
from $298per person
Hilton Head Island
5h 09m2 stops
from $341per person
Columbia
5h 18m2 stops
from $369per person
Florence
5h 49m2 stops
from $713per person
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Booking Insights

Price, demand and travel trends for Denver to South Carolina flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

What are the cheapest fares from Denver to South Carolina recently?

The cheapest fares from Denver to South Carolina on KAYAK in the last week were to Charleston (CHS) from $259 round-trip and to Hilton Head Island (HHH) from $341 round-trip.

How do fares into airports in South Carolina compare?

According to KAYAK data from the last 12 months, the cheapest airports to fly into South Carolina from Denver are:

• Columbia Metropolitan (CAE) (avg. price $402)
• Greenville (GSP) (avg. price $415)
• Charleston (CHS) (avg. price $427)

Are flights from Denver to South Carolina cheaper or more expensive than last year?

Fares from Denver to South Carolina are about 11% lower than they were in November last year, averaging $393 round-trip.

What's the cheapest month to fly from Denver to South Carolina?

August is typically the cheapest month to fly from Denver to South Carolina, with round-trip fares averaging $385. March and July are usually the most expensive, averaging $460 and $456, respectively.

How do fares from Denver to South Carolina vary by day of the week?

On average, Wednesday is the cheapest day to fly from Denver to South Carolina and Monday is the most expensive. Looking at the past 12 months of KAYAK data, it's 15% more expensive to fly on a Monday compared to Wednesday.

What's the best time of day to fly from Denver to South Carolina?

It's cheapest to fly to South Carolina at night with average prices of $378. The evening is the most expensive time to fly, with average prices of $539.

What's the best time to book a flight from Denver to South Carolina?

Book your flights 22 weeks before your trip. KAYAK data collected over the past 12 months shows that booking in this window can save you around 46% compared to booking at the last minute (within 2 weeks of departure).

Key details for Denver to South Carolina flights

Low season

January

Cheapest flight

$122
Beat the crowds with an average 32% drop in travelers.
The most popular month to fly with an average 34% increase in travelers.
One-way flight from Denver to Charleston

Your Denver to South Carolina flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • Is now a good time to book a flight from Denver to South Carolina?

    Yes. Fares from Denver to South Carolina are low right now. As a rule of thumb, a round-trip under $345 (cheaper than most fares this year) is a good deal, so if you spot one at or below that, it's a good time to book.

  • How much should I budget for a flight from Denver to South Carolina?

    Over the past 12 months, round-trip fares from Denver to South Carolina have typically cost between $345 and $557.

  • What are the main airports serving South Carolina?

    There are 10 airports in South Carolina. 43% of KAYAK users choose Charleston (CHS) as their arrival airport, while 27% choose Greenville (GSP).

  • Which airlines fly nonstop from Denver to South Carolina?

    Based on the flight schedule for the next 3 months, 2 airlines offer nonstop flights on this route:

    • United Airlines
    • Southwest

  • Which destinations in South Carolina can I fly nonstop from Denver?

    Based on the flight schedule for the next 3 months, you can fly nonstop from Denver to 2 destinations in South Carolina: Charleston and Greenville.

  • Is it cheaper to fly with a layover from Denver to South Carolina?

    Yes, nonstop flights from Denver to South Carolina average $465 over the past 12 months, but flights with a layover can cost less. The most affordable connecting airports are:

    • Philadelphia (PHL) (avg. price $299)
    • Providence-TFGreen (PVD) (avg. price $302)
    • Cleveland Hopkins Intl (CLE) (avg. price $312)

  • How long is a flight from Denver to South Carolina?

    Nonstop flights from Denver to South Carolina take 3h 14m on average. The fastest scheduled flight takes 3h 02m, flying into Greenville (GSP).

  • Which cabin classes are available from Denver to South Carolina?

    On flights from Denver to South Carolina you can book Economy Class, Business Class or First Class.

  • What are the earliest and latest flights from Denver to South Carolina?

    The earliest nonstop flight from Denver to South Carolina departs at 9:40 am and the latest leaves at 3:30 pm. Nonstop flights take about 3h 14m.

Your guide to booking Denver to South Carolina flights

Get tips on when to book, when to fly and what to know before your trip.
  • If you can plan ahead, the sweet spot for booking your flight is 22 weeks before your trip. KAYAK data shows fares in this window are around 46% lower than last-minute bookings (made within 2 weeks of departure). Not ready to commit? Set a Price Alert and we'll let you know when prices change.
  • Flexible with your dates? Fly in August to save some money. It's typically the cheapest month on this route, while flights in March will cost you the most.
  • Fly out on a Wednesday to get the cheapest fares. Avoid Monday flights, which are about 15% more expensive.
  • If you're watching your budget, fly into Columbia Metropolitan (CAE) which has the lowest average airfare in the region. Just remember to budget for any onward travel by bus, car or domestic flight.
  • Start your trip in Myrtle Beach, the most popular destination in South Carolina. From there, it's easy to continue on to other popular spots such as Charleston, Hilton Head Island and Greenville.
  • Time or money? If speed matters most, fly from Denver to Greenville (GSP). If you're after the lowest fares, Columbia Metropolitan (CAE) is usually your best bet.

Reviews of the top 5 airlines serving from Denver to South Carolina

 
Need help choosing which airline to fly with from Denver to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4222 reviews
8.0Comfort
7.5Entertainment
8.6Crew
8.1Boarding
7.0Food
Airline reviews

I fly out every other weekend and this is the 4th time my flight has been delayed at Southwest. I will be flying out twice a month on average for the next 6-7 months. If this is your average ‘on time’ I’ll probably be flying another airline.

8.0 ExcellentDelores, Oct 2026
Read more Southwest reviews

I fly out every other weekend and this is the 4th time my flight has been delayed at Southwest. I will be flying out twice a month on average for the next 6-7 months. If this is your average ‘on time’ I’ll probably be flying another airline.

WiFi was inoperable - second in four recent Southwest flights where that was true. I need WiFi for work and if Southwest cannot provide, I’ll stop using it

A List preferred boarding was nice Asked for a mask and cheerfully received Denver bag check-in is tricky. Not near other checking desk. Have to navigate to east security and up to level six for bag checkin. TSA busy and 20 minutes process thru pre lines Denver train to gates quick but one more thing to plan time for and long concourse walk to gate

Southwest has inacted unfriendly customer policies like other airlines. Watch the fine print very carefully if you are having to alter flight arrangements. Rules are now complicated and very stilted to travelers sacrificing travel funds (unlike before where the simple, straight forward flight change policy was worth the extra premium for ticket price.) On the positive side, SW Flight crews are still wonderfully helpful.

Poor customer service, no accommodation for passengers when the flight was delayed over 5 hours.

The flight was late. The crew was rude. There was no food. Cramped and uncomfortable. Nothing about this flight was good.

It was great. The gate staff were very helpful in Portland when my son forgot his rolling bag and had to go back to get it just in time to make it on the plane. We really appreciate that. Great job!

This leg was much better, but we did have to have a 3 hour lay o er after coming from a very exhausting hiccup with our flight from BNA to Den

My flight from Denver to Minneapolis was excellent. My flight from Minneapolis to Denver was one of the worst I flights I have ever experienced. I had a window seat, the gentleman in the middle seat was morbidly obese and SW should have made him purchase two seats. His elbow dug into my arm most of the way even after I asked to please be careful. I was literally squashed between the him and the window with no wiggle room. The plane was full so it was not possible to ask for a different seat. I realize I should have complained to the flight attendant but I didn't feel anything could be done to rectify the situation. I fly SW often, I will continue to do so as this was my first negative experience.

Everything went smoothly and we even arrived a little bit early.

There was an incredibly surly flight attendant that ruined the experience

First flight was delayed which resulted in missing our connecting. As a result class was downgraded to economy on a later flight.

Unprepared to rebook a flight of people. Uncommunicative. When I received updates in the app it was well after the announcement in the hold room. Offered a single $12 meal voucher, not enough for a sandwich at DEN, for a 17 hour delay. No one was able to explain their meal or hotel reimbursement policy for this cancellation, just handed a card to call the Help desk. My previous flight went through several delays and was finally cancelled, without explanation. The customer help desk closed while there was a long line. I then waited in line for a gate agent almost an hour while simultaneously on hold and trying to text with a remote Delta agent. Communicating with the text agent was almost impossible; they could not find any flights that got me back to my original city before the following evening. Kept offering itineraries that did not get me back to my origin airport or involved additional layovers. In 50 minutes on hold, never got through to an agent by phone. Finally spoke to one of the gate agents who was able to rebook on a red eye that had only one stop and got me back in the afternoon the next day, rather than late evening. Later by email, Delta offered 10,000 loyalty points for the inconvenience of the cancellation. The crew on the red eye flight were delightful. I don’t remember any food or entertainment on that flight.

I have Precheck. Flew HPN to DEN and return this past weekend. Delta didn't attach my Precheck number to this trip. So it was waiting in general line especially in Denver. Unavailable.

worst flight ever from Delta, it got delayed and kept on delaying..

Terrible. Four hour delay because Delta could not find crew to man the aircraft. Terrible communication. Terrible insight into the delays. One of the worst flight experiences I’ve had.

Mechanic delay in addition to a 2 hour change in takeoff time was frustrating.

Boarding was organised and relaxed. Crew were fantastic! Seats were lacking padding causing butt pain and stiffness.

Flights on time. .Ride was as comfortable as can be expected in steerage. Luggage arrived at destination. Attendants were fairly friendly.

First, the flight was schedule to leave at 12:08. Delayed to 12:38. It is 12:58 and I am sitting at the gate. The staff are not communicating with us (just tell me it’s gonna be five hours if that’s the case, quit hufflepuffing around like you’re trying to board us when the plane isn’t even here and you don’t know where your crew are. I’m still waiting for any communication about the further delay. This is a rebooked flight from a cancelled flight yesterday, when the airline failed to fulfill its fiduciary responsibility to hotel and cover transport for overnight cancelations. Asking about the food on the flight? What food?!? Delta doesn’t serve meals unless you pay for them and you really want me to give delta a high rating for passing out processed snacks (fun size!)? Can we be for real. Delta is cementing itself in history as one of the cheap, stingy, outdated, glory days are over airlines, and it shows. I took this flight knowing delta was going to provide below level service but this is beyond burgers!! I can’t believe a multi billion or dollar company looked straight in my eyes yesterday and I told me this wasn’t their fault and there for the extra cost in hotel and hundreds of dollars in Ubers are MY RESPONSIBILITY. The only thing I am at fault for is believing delta is reputable company worthy of my dollars. I’m not even sure I want to be compensated unless it is cash because I would rather die never traveling again than to put money in their pockets.

United staff were very communicative, the new starlink Wifi is amazing as I was able to work easily.

I am United’s newest fan. The planes are clean, the staff is so friendly and snacks are more than just old pretzel crumbles. The captain came and said hello! Truly amazing experience

Plane arrived an hour before departure. Plane was completely boarded and ready for push back when they decided they needed to change a tire. 1 hour delay on the plane when this could have been done before we got on the plane.

Usual wait for over a half hour for a gate at Ohare. They tell you you'll get there early then sit on the plane and wait almost an hour

It was fine for the most part. But the volume on the announcements was way too loud, and the cabin temperature was chilly. We had the hardest landing I've ever experienced- I think it hurt my back, and the tires squealed when we touched down.

Not a United thing, but late afternoon departures from Denver with thunderstorms is always prone to delays.

Really delayed, no effort to support customers other than “sometimes we run late.”

The flight was excellent. Their was no service as we boarded, the flight attendants spent about 30 minutes just taking and not really caring that the cabin was about 80 degrees and did not offered any beverage to first class passengers or any passenger. The flight from DEN to ONT is not long but not under an hour, we received one drink and bag of chips if you were lucky. I was in first class…. I did leave my hat on the plane and it only took less than five minutes for a United rep to locate and bring it to me.

Flight was late to take off Plane broke down Had to move everyone to another plane Told we weren’t going to LGA but Newark Also told we would be taken to NY But United lied and we ended up at Newark at 2 in the morning Horrible experience. And the experience of trying to get compensation from United is just as bad. They could not care less about their passengers Never again!

Flight was delayed “due to earlier delays of that plane”, so we were nearly three hours late.

Flight was canceled after 5 hours of delays sitting at the airport

I’m still in Boston and I was supposed to be home yesterday at 2:30pm

Fort Lauderdale doesn't have Priority Security line so why was such option available for purchase? I need a refund back

1/2 full flight, nice and comfy flight. On time, good service

Both ways the people in the rear section of the plane were forced to check their carry on bags. I would understand this if the size and number of bags were not limited, but I do not understand why there is not room for one small overhead bag per person, even if the flight is full. I could watch the baggage handlers loading the extra luggage from my window and I’m pretty sure mine wouldn’t have survived undamaged, even though it is new and sturdy.

Entertainment, clean plane and funny pilot over the intercom was excellent… however, gate agent was rude and was probably a Spirit employee before they went bankrupt… there were 3 flight attendants - 2 of them didn’t want to be there the other one was kind and nice… I want you to recognize how you have to compete with Delta or South West airlines or even American Airlines which would choose over you at any given day from here on out. Please treat people respectfully. If you hate working in this industry - go and work somewhere else. The flight was very empty and it shouldn’t be hard to crack a smile once in a while. Very disappointing… I remember flying Jet Blue back in the day from Dulles IAD to LAX and you guys were super cool and fancy and made flying fun again - truly elevated the experience. Don’t become the next most hated airline… you can do better . I want you to succeed…

3.5 hour delay because of “mundane” mx issue. Aircraft had to be towed 3 times.

The crew was not nice this time. I asked for a drink one time and the girl didn’t say anything to me and just got me the hot drink while walking super fast to the back. We were sitting in the back and she wasn’t doing anything except socializing. She was upset I asked for something and she had to do her job. I also didn’t fully have it in my hands when she handed it to me so it was dangerous. She was abrupt and rude. She wouldn’t allow for people to spread out like previous flights we had been on if they were empty, and there were empty rows. It was strange and she enjoyed being angry at us.

The flight was delayed. I upgraded to more room. I can't imagine how small the regular seats are I haven't upgraded for my return flight yet.

Smooth boarding and friendly crew. Unfortunately as soon as we boarded the unit that provides air circulation failed. The pilot informed us and requested maintenance technicians to check it out. The plane became uncomfortably warm without any fresh air coming in. Plus the repair delayed our departure. I am glad the maintenance crew were able to fix the problem. I also was without use of my tv monitor for the first 1/3rd of the trip.

Not too much it was pretty good all the way around

The flight attendants were extremely sourly and borderline rude. I did not feel appreciated as an AA customer once.

As we approached Denver, we encountered quite a bit of turbulence. I know this can sometimes be the case as I frequently fly this route but not on American. My gripe: Usually a pilot or co-pilot alerts passengers to the possibility of turbulance ahead of time. This did not occur nor did he communiucate during what was a pretty rough ride.

Terrible. Our luggage was delayed and couldn’t be delivered for several days. We got bad information from the airline agents at baggage claim. We had to pick up our car so we wouldn’t be charged for an extra day. We got lost in the maze of airport parking. The baggage claim agents didn’t offer us any compensation for our extra time and expense. We are tired, hungry and very frustrated.

Mechanical delay and no compensation. Missed connection as a result of their delay. Mediocre performance and service. Horrible airline currently with horrible culture.

Any sort of gluten free snack option would be nice

Crew was late. Baggage was late. 2hs inside the plane waiting fro de-icing and traffic. A 3:30hs flight ended up being almost 6hs inside the airplane.

Timely boarding process, made up for lost time even after a lengthy wait for de-icing

It would have been better if I could have had my flight on time. It was delayed for 5 hours. Caused me to not be able to fulfill my promise to my granddaughters. Other than that it was a good trip.

11h50m total delay. Had to switch to another flight that was still a 7h30m delay.

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