$101 Find Cheap Flights from Denver to South Carolina - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to South Carolina departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from Denver to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston2 stops$286
Myrtle Beach
Myrtle Beach1 stop$268
Greenville
Greenville1 stop$259
Columbia
Columbia1 stop$321
Florence
Florence1 stop$389
Charlotte
Charlottenonstop$250
Charleston
Charleston2 stops$286
Myrtle Beach
Myrtle Beach1 stop$268
Greenville
Greenville1 stop$259
Columbia
Columbia1 stop$321
Florence
Florence1 stop$389
Charlotte
Charlottenonstop$250

Book Cheap Denver to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to South Carolina

Mon, Sep 21 - Tue, Sep 29
Frontier Logo
1:23 pm - 6:46 pm
DEN
-
CLT
3h 23mnonstop
Frontier Logo
12:10 pm - 11:00 pm
CLT
-
DEN
12h 50m
1 stop
$250Frontier
Fri, Aug 28 - Mon, Aug 31
Frontier Logo
11:00 am - 4:26 pm
DEN
-
CLT
3h 26mnonstop
Frontier Logo
5:31 pm - 8:14 am
CLT
-
DEN
16h 43m
1 stop
$251Frontier
Tue, Aug 18 - Tue, Aug 25
Delta Logo
6:00 am - 3:32 pm
DEN
-
HHH
7h 32m
1 stop
Delta Logo
12:15 pm - 5:57 pm
HHH
-
DEN
7h 42m
1 stop
$281Delta
Tue, Aug 25 - Wed, Sep 2
Delta Logo
6:00 am - 3:32 pm
DEN
-
HHH
7h 32m
1 stop
Delta Logo
12:15 pm - 8:01 pm
HHH
-
DEN
9h 46m
2 stops
$286Delta
Sat, Aug 15 - Sat, Aug 22
United Airlines Logo
7:40 am - 4:27 pm
DEN
-
CHS
6h 47m
1 stop
United Airlines Logo
4:58 pm - 9:44 pm
CHS
-
DEN
6h 46m
1 stop
$289United Airlines
Sat, Aug 22 - Mon, Aug 24
Southwest Logo
7:35 am - 7:35 pm
DEN
-
SAV
10h 00m
2 stops
Southwest Logo
1:05 pm - 7:40 pm
SAV
-
DEN
8h 35m
2 stops
$289Southwest
Tue, Sep 8 - Thu, Sep 10
Southwest Logo
11:15 am - 9:10 pm
DEN
-
CHS
7h 55m
2 stops
Southwest Logo
8:40 am - 1:20 pm
CHS
-
DEN
6h 40m
1 stop
$294Southwest
Mon, Aug 17 - Mon, Aug 24
United Airlines Logo
10:01 am - 3:28 pm
DEN
-
CHS
3h 27mnonstop
United Airlines Logo
8:30 am - 10:20 am
CHS
-
DEN
3h 50mnonstop
$295United Airlines
Tue, Aug 18 - Tue, Aug 25
American Airlines Logo
6:15 am - 4:38 pm
DEN
-
HHH
8h 23m
1 stop
American Airlines Logo
3:27 pm - 7:19 pm
HHH
-
DEN
5h 52m
1 stop
$305American Airlines
Tue, Aug 18 - Tue, Aug 25
American Airlines Logo
5:03 am - 1:34 pm
DEN
-
CAE
6h 31m
1 stop
American Airlines Logo
7:00 am - 11:45 am
CAE
-
DEN
6h 45m
1 stop
$325American Airlines
Booking Insights

KAYAK's insights & trends for Denver to South Carolina flights

Get data-powered insights and trends into flights from Denver to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Denver to South Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Denver to South Carolina departing in August.

Flight prices are below average for this route right now.

Flights to South Carolina from Denver usually cost between $344 and $523 in August.
The lowest price found in the past 5 days was $286 on Multiple Airlines (Aug 20-Aug 26).

What is the cheapest Denver to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Denver found in the last 5 days was to Charleston, at $295 round-trip. The most popular route is from Denver (DEN) to Charleston (CHS), and the cheapest round-trip airline ticket found on this route in the last 5 days was $295.

What is the cheapest time of day to fly to South Carolina?

The average price for all round-trip flights from Denver to South Carolina depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to South Carolina is generally in the afternoon, when round-trip flights cost $405 on average. Morning departures are around 6% more expensive than evening flights, on average. The most expensive time of day to fly to South Carolina is generally at night, which is peak travel time and where the average cost of a ticket is $622.

Can I save money by flying with a layover from Denver to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $475 on average.

What is the cheapest month to fly from Denver to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Denver to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Denver to South Carolina is April, when tickets cost $393 (return) on average. On the other hand, the most expensive months are March and June, when the average cost of round-trip tickets is $458 and $452 respectively.

What’s the cheapest day of the week to fly from Denver to South Carolina?

The average price of all round-trip flights from Denver to South Carolina clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to South Carolina on a Sunday and more expensive on a Thursday. On your return trip to Denver, you should consider flying back on a Tuesday, and avoid Sundays for better deals.

How far in advance should I book a flight from Denver to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Denver to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Denver to South Carolina, you should book around 5 weeks before departure, which saves you about 59% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 23 weeks before departure.

Good to know

Low season

January

Cheapest flight

$101
Best time to beat the crowds but there is an average 1% increase in price.
Most popular time to fly with an average 2% increase in price.
Flight from Denver to Myrtle Beach

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Denver to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Denver to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Denver to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Denver to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Denver to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Denver to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Denver to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Denver to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Denver to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Denver to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Denver to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4238 reviews
7.5Entertainment
8.0Comfort
8.6Crew
7.0Food
8.1Boarding
Airline reviews

The flight was late. The crew was rude. There was no food. Cramped and uncomfortable. Nothing about this flight was good.

2.0 MediocreIrene, Jun 2026
DEN - SFO
Read more Southwest reviews

The flight was late. The crew was rude. There was no food. Cramped and uncomfortable. Nothing about this flight was good.

It was great. The gate staff were very helpful in Portland when my son forgot his rolling bag and had to go back to get it just in time to make it on the plane. We really appreciate that. Great job!

This leg was much better, but we did have to have a 3 hour lay o er after coming from a very exhausting hiccup with our flight from BNA to Den

My flight from Denver to Minneapolis was excellent. My flight from Minneapolis to Denver was one of the worst I flights I have ever experienced. I had a window seat, the gentleman in the middle seat was morbidly obese and SW should have made him purchase two seats. His elbow dug into my arm most of the way even after I asked to please be careful. I was literally squashed between the him and the window with no wiggle room. The plane was full so it was not possible to ask for a different seat. I realize I should have complained to the flight attendant but I didn't feel anything could be done to rectify the situation. I fly SW often, I will continue to do so as this was my first negative experience.

Everything went smoothly and we even arrived a little bit early.

Connecting flight is on time and boarding was a breeze!

WiFi did not work. For as outrageous as these flights cost, when they’re advertised with certain services/ features they should be in working order

I would have liked to arrive on time - not 5 hours late!

1.5 hour delay, poor service, no compassion from the crew. Terrible experience

Our flight was diverted from being a non-stop to getting within 150 miles and requiring another plane. We heard 4 or 5 different versions from SW as to why we had to stop, then wait for a replacement plane. Five hour delay, weather did not come up as a single excuse.... communication was not clear and well explained. No one really took charge!

I have Precheck. Flew HPN to DEN and return this past weekend. Delta didn't attach my Precheck number to this trip. So it was waiting in general line especially in Denver. Unavailable.

worst flight ever from Delta, it got delayed and kept on delaying..

Terrible. Four hour delay because Delta could not find crew to man the aircraft. Terrible communication. Terrible insight into the delays. One of the worst flight experiences I’ve had.

Mechanic delay in addition to a 2 hour change in takeoff time was frustrating.

Boarding was organised and relaxed. Crew were fantastic! Seats were lacking padding causing butt pain and stiffness.

Flights on time. .Ride was as comfortable as can be expected in steerage. Luggage arrived at destination. Attendants were fairly friendly.

First, the flight was schedule to leave at 12:08. Delayed to 12:38. It is 12:58 and I am sitting at the gate. The staff are not communicating with us (just tell me it’s gonna be five hours if that’s the case, quit hufflepuffing around like you’re trying to board us when the plane isn’t even here and you don’t know where your crew are. I’m still waiting for any communication about the further delay. This is a rebooked flight from a cancelled flight yesterday, when the airline failed to fulfill its fiduciary responsibility to hotel and cover transport for overnight cancelations. Asking about the food on the flight? What food?!? Delta doesn’t serve meals unless you pay for them and you really want me to give delta a high rating for passing out processed snacks (fun size!)? Can we be for real. Delta is cementing itself in history as one of the cheap, stingy, outdated, glory days are over airlines, and it shows. I took this flight knowing delta was going to provide below level service but this is beyond burgers!! I can’t believe a multi billion or dollar company looked straight in my eyes yesterday and I told me this wasn’t their fault and there for the extra cost in hotel and hundreds of dollars in Ubers are MY RESPONSIBILITY. The only thing I am at fault for is believing delta is reputable company worthy of my dollars. I’m not even sure I want to be compensated unless it is cash because I would rather die never traveling again than to put money in their pockets.

Boarding was great. The flight landed early. It took the crew over an hour and a half to bring out drinks. I paid to upgrade my seat to Comfort+ only to be near a crying/screaming baby who was seldom quiet. Noise-cancelling earbuds didn’t even help. Waste of money to upgrade.

This flight was supposed to land at 10:55 pm on January 14th. Instead, it landed at 3:20 am on Monday, January 15th, resulting in a completely lost day due to not going to bed until 5:00 am.

We finally got on a flight about 10:45 that was to leave at 7:30. Bah humbug!

Flight was delayed “due to earlier delays of that plane”, so we were nearly three hours late.

Very easy ! Use the kiosk and bag drop and right to security within 10 min

This planes staff was top tier. Everything went great and had a great flight home.

Destroyed my suitcase. Tired of talking about it. Cancelling my unite mileage plus account.

New plane was lovely. Crew customer service is always lax but expected. Kraft on time and arrived safely.

It was a short flight so I was expecting too much

Had a one hour delay due to mechanical issue. I didn’t think I’d be able to make my connecting flight, but they waited for me and greeted me when I arrived to help things run smooth.

O’hsre taxi and deboarding took 40 minutes. Needed 20 minutes extra time between connecting flights to avoid running through terminal.

Was great in general, try to respect time and excuses when slight changes have been made, appreciated!

Really hard landing... as in slammed into the runway then hit the brakes really hard ...

The flight attendants were extremely sourly and borderline rude. I did not feel appreciated as an AA customer once.

As we approached Denver, we encountered quite a bit of turbulence. I know this can sometimes be the case as I frequently fly this route but not on American. My gripe: Usually a pilot or co-pilot alerts passengers to the possibility of turbulance ahead of time. This did not occur nor did he communiucate during what was a pretty rough ride.

Terrible. Our luggage was delayed and couldn’t be delivered for several days. We got bad information from the airline agents at baggage claim. We had to pick up our car so we wouldn’t be charged for an extra day. We got lost in the maze of airport parking. The baggage claim agents didn’t offer us any compensation for our extra time and expense. We are tired, hungry and very frustrated.

Mechanical delay and no compensation. Missed connection as a result of their delay. Mediocre performance and service. Horrible airline currently with horrible culture.

Any sort of gluten free snack option would be nice

Crew was late. Baggage was late. 2hs inside the plane waiting fro de-icing and traffic. A 3:30hs flight ended up being almost 6hs inside the airplane.

Timely boarding process, made up for lost time even after a lengthy wait for de-icing

It would have been better if I could have had my flight on time. It was delayed for 5 hours. Caused me to not be able to fulfill my promise to my granddaughters. Other than that it was a good trip.

11h50m total delay. Had to switch to another flight that was still a 7h30m delay.

Delay 14 hours! Missed all connections and had to fly different airline the next day.

The seats were roomier than other airplanes I’ve been on.

The security line at JFK was one of the longest I’ve ever experienced - probably 45 minutes. I don’t know if JetBlue has control over it, but it detracted from the overall experience. Entertainment had good options, but the volume control was a bit small to tap on and the screen had a fair amount of interference blips. Clearer picture would have been better.

I liked the entertainment on JetBlue, the service from JFK to JAX was terrible at best

I usually dont fly JeTBlue and I dont think I will ever do it again. The flight was delayed fee time, nobody was giving us any info at at the airport, gate changing, the slowest and poorly organized boarding ever, rude staff.. huh

The flight was delayed. I upgraded to more room. I can't imagine how small the regular seats are I haven't upgraded for my return flight yet.

Horrible - for the first time in my life i was denied boarding an international flight because the name used on my ticket - Josh - was not exactly the same as my passport - Joshua. At no time during ticketing, online check-in, or at the airport flying from Boston to NY was i notified of a problem. It was only at boarding from NY to Costa Rica I was informed of the problem and by then it was too late. After missing the flight I was told by airport Jet Blue staff, including a supervisor, that it was my problem and they could not assist because i bought "the cheapest fare". i was hung up on twice by JetBlue customer service, including once by a supervisor. I blame Kayak and your awful partner ChatDeal for even allowing me to purchase an international ticket without verifying this - you effectively sold me a ticket i could not use. Shame on you and shame on ChatDeal for doing nothing to help me resolve the situation. What a scam.

Like the variety of entertainment options. One crew member was a little on the rough/rude side. Boarding was a mess, attendants didn't do a great job of helping with the luggage storage and it delayed us a couple of minutes.

The flight kept getting delayed, but the ground crew did not communicate well to the passengers in the terminal. First, we were told that it was an engine issue. That was understandable. We asked, after the third delay, if it would be canceled; they reassured us that that would not happen because a new plane was on its way from Washington DC. Four hours later, that is exactly what happened. No announcement was made only people who had the JetBlue app learned of the cancellation. They rebooked us on a flight that would get into our destination 36 hours after our original time I had to spend an exorbitant amount of money to book an additional flight with a different airline, the following morning in order to make it to my conference in time. Not to mention the fact that by the time I discovered the cancellation on the departures board, it was too late for me to receive a refund on my lodging in the destination city for that night. Because I had booked with KAYAK, I did not receive any JetBlue email with rebooking information. This is what the information information desk kept telling everyone who inquired about a rebooking. This was my first time flying with JetBlue. Needless to say, after extremely poor communication andover $1000 of additional expense later, I will not be flying with them again.

We were several hours delayed due to confusion during boarding. Evidently the crew could not match the manifest with the boarded customers. After significant time trying to find individuals on board, a crew member walked through the entire plane re-scanning each of our boarding passes. Then we had to wait for a new slot to depart, and when we landed, our gate was not ready. It was a complete goat rodeo from start to finish.

Smooth boarding and friendly crew. Unfortunately as soon as we boarded the unit that provides air circulation failed. The pilot informed us and requested maintenance technicians to check it out. The plane became uncomfortably warm without any fresh air coming in. Plus the repair delayed our departure. I am glad the maintenance crew were able to fix the problem. I also was without use of my tv monitor for the first 1/3rd of the trip.

Everything you need to know for your flight from Denver to South Carolina

Information on your arrival and departure airports