$75 Find Cheap Flights from Denver to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to South Carolina departing on 10/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Denver to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Denver to South Carolina, as well as popular online travel agencies
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Cheap Flights from Denver to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$244
Myrtle Beach
Myrtle Beach1 stop$181
Greenville
Greenville1 stop$171
Columbia
Columbia1 stop$269
Florence
Florence1 stop$492
Charlotte
Charlottenonstop$149
Charleston
Charleston1 stop$244
Myrtle Beach
Myrtle Beach1 stop$181
Greenville
Greenville1 stop$171
Columbia
Columbia1 stop$269
Florence
Florence1 stop$492
Charlotte
Charlottenonstop$149

Book Cheap Denver to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to South Carolina

Sat, Oct 4 - Tue, Oct 7
United Airlines Logo
9:52 am - 3:13 pmDEN-CLT
3h 21mnonstop
United Airlines Logo
8:29 am - 10:09 amCLT-DEN
3h 40mnonstop
$149United Airlines
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Sun, Sep 21 - Mon, Oct 6
Frontier Logo
11:59 pm - 7:05 pmDEN-CLT
17h 06m1 stop
Frontier Logo
5:20 pm - 7:07 pmCLT-DEN
3h 47mnonstop
$151Frontier
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Thu, Oct 30 - Tue, Nov 4
American Airlines Logo
1:24 pm - 6:50 pmDEN-CLT
3h 26mnonstop
American Airlines Logo
8:35 am - 10:26 amCLT-DEN
3h 51mnonstop
$165American Airlines
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Sat, Oct 25 - Tue, Oct 28
Southwest Logo
6:30 am - 2:45 pmDEN-GSP
6h 15m1 stop
Southwest Logo
6:05 am - 12:40 pmGSP-DEN
8h 35m1 stop
$171Southwest
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Tue, Oct 7 - Sun, Oct 12
Southwest Logo
11:40 pm - 9:55 amDEN-CLT
8h 15m1 stop
Southwest Logo
5:25 am - 7:05 amCLT-DEN
3h 40mnonstop
$175Southwest
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Wed, Oct 15 - Wed, Oct 22
American Airlines Logo
11:59 pm - 5:07 amDEN-CLT
3h 08mnonstop
American Airlines Logo
5:57 pm - 7:34 pmCLT-DEN
3h 37mnonstop
$179American Airlines
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Sat, Oct 4 - Tue, Oct 7
 Logo
6:55 pm - 8:11 amDEN-CLT
11h 16m1 stop
 Logo
6:00 am - 1:08 amCLT-DEN
21h 08m1 stop
Fri, Oct 17 - Wed, Oct 22
 Logo
11:45 pm - 7:53 amDEN-CLT
6h 08m1 stop
 Logo
6:00 am - 3:24 pmCLT-DEN
11h 24m1 stop
Thu, Oct 2 - Sun, Oct 5
Delta Logo
12:45 am - 10:44 amDEN-GSP
7h 59m1 stop
Delta Logo
5:30 am - 8:34 amGSP-DEN
5h 04m1 stop
$237Delta
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Mon, Dec 8 - Thu, Dec 11
Delta Logo
3:14 pm - 11:42 pmDEN-MYR
6h 28m1 stop
Delta Logo
6:56 pm - 12:16 amMYR-DEN
7h 20m1 stop
$237Delta
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Booking Insights

KAYAK's insights & trends for Denver to South Carolina flights

Get data-powered insights and trends into flights from Denver to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Denver to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Denver found in the last 72 hours was to Charleston, at $255 round-trip. The most popular route is from Denver (DEN) to Charleston (CHS), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $255.

Can I save money by flying with a layover from Denver to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $377, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Denver to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Denver to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Denver to South Carolina is January, when tickets cost $347 (return) on average. On the other hand, the most expensive months are December and March, when the average cost of round-trip tickets is $569 and $489 respectively.

What’s the cheapest day of the week to fly from Denver to South Carolina?

The average price of all round-trip flights from Denver to South Carolina clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to South Carolina on a Tuesday and more expensive on a Sunday. On your return trip to Denver, you should consider flying back on a Tuesday, and avoid Sundays for better deals.

How far in advance should I book a flight from Denver to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Denver to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Denver to South Carolina, you should book around 4 weeks before departure, which saves you about 48% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Good to know

Low seasonFebruary
Cheapest flight$75
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly and prices are also 7% lower on average.
Flight from Denver to Charleston

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Denver to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Denver to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Denver to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Denver to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Denver to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Denver to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Denver to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Denver to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally in the evening, when round-trip flights cost $450 on average. Morning departures are around 16% more expensive than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the morning, which is peak travel time and where the average cost of a ticket is $522.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Denver to the following destinations at these prices or less: Charlotte $144 one-way - $269 round-trip

Reviews of the top 5 airlines serving from Denver to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Denver to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Denver to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4248 reviews
7.0Food
8.1Boarding
7.5Entertainment
8.6Crew
8.0Comfort
Airline reviews

I wish they had movie screens in the headrests. The seats are much improved, more legroom and recently renovated. Bathroom was clean. Staff was outstanding!!

10.0 ExcellentG, Sep 2025LAS - ATL
Read more Southwest reviews

I wish they had movie screens in the headrests. The seats are much improved, more legroom and recently renovated. Bathroom was clean. Staff was outstanding!!

As always, the entire Southwest experience was wonderful, from online booking to flight to baggage retrieval. Very grateful.

The weather could have been better. There was a 40 minute ATC delay in SFO because of marine fog and a micro cell storm delayed landing and take-off at Nashville. The gate was changed 5 minutes from boarding from gate B3 to gate C23 at Nashville airport.

After being assaulted by a flight attendant I was then brushed off as oh well because he long braids didn’t mean to whip me in the eye. I have filed complaints and will see. But like any other issue I’ve had with kayak involved it’s been trash. Last time I’ll be using your app

AC sub par. WiFi not working correctly. Ac sucked. Seats very narrow.

Near 4 hour flight with only 1 service. Had to use call button to request water. Internet and power not working until into flight. Internet would stop working during flight.

Southwest's seats are the least comfortable I have ever sat in.

The cabin was quiet for the redeye flight. The area was clean. The staff was great. The 787 Max was in good condition. Drawbacks were that the seat widths were tight for some passengers. The seat padding was at best average and for a long flight uncomfortable.

Southwest like most American domestic airlines, is a mediocre airline. But it is among the cheapest. Oh well.

My flight was delayed 50 minutes and we were rushed to board to then sit for 15 minutes until the pilot arrived. Unacceptable since we could have waited to board. Also the delayed flight was updated AFTER we boarded to more than the 10 minutes as originally stated.

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

Crew was good. The reservation got mixed up and they didn't have my TSA number. I am also a Silver Medallion and wasn't able to use Sky Priority.

Delta made it easy, comfortable and timely. The crew was fantastic.

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

Mechanic delay in addition to a 2 hour change in takeoff time was frustrating.

Delayed due to thunderstorms and no in-flight service due to rough weather — both of which are out of Delta’s control. Flight was good overall.

The flight attendants in SLC were rude. I arrived 40 minutes early to gate. Ticket said I needed check in for seat assignments and tried check in and attendants said they weren’t doing it. And proceeded to never call me to give me a ticket so when time to board I received the very last seat. Please relay to employees to do their job better..,

Impressed with the service despite turbulence because of the weather. Both flights arrived before their scheduled times.

Great experience…left a bit behind schedule but made up fir that in the air and landed 10 minutes early 😁

Electric plugs didn't work. Entertainment system wasn't working

The design of the light switch on the arm rest is ridiculous.

The gate attendant let me walk right by her with a bag too big for the overhead compartment

Overall, it was a good experience. Boarding was good and there was plenty of overhead bin space for everyone’s carryons (even when we boarded toward the end). Only improvement would be to offer trash service more regularly.

David went above and beyond to make our flight the best that it could be

No food service almost missed because of first flight delays

Had a hard time finding my assigned seat. No attendants to assist.

The negative was the wait at the airport coming back. I checked my bags in, an hour before boarding and I get the notification that my flight was delayed. Rather had gotten the notification while I was at the hotel. Then it was delayed 3 x’s. Ugh!

Given it’s a red-eye into Charolotte, we didn’t get any food. The survey does not include “N/A” so the rating will be skewed.

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

American airlines suck they delay the flights all the time made me sleep in an airport because my flight was delayed and I miss my connecting flight

There's nothing I liked about it. For first off I scheduled this trip two weeks in advance then they delayed my flight which messed up my whole trip. So I scheduled it for the following weekend thinking there won't be a delay and guess what as soon as I got to the airport we said in the airplane on the tarmac for an hour and a half. Not only was it delayed I missed my connecting flight meaning I had to stay the night at Dallas-Fort Worth airport sleeping on the floor. I will tell you this I will never fly American airlines ever again I have had nothing but horrible experience with them and I just throw money at them

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Don’t know they cancelled the flight day before I was to leave. They sent a email at 9:00 pm at night saying they cancelled. That is the smooth way to say we don’t want your business! I think they didn’t have enough people booking so they cancelled the flight! It’s all about the money anymore there is no honesty in business.

Having to reschedule flights a day later, they loaded by luggage on the wrong plane from Little rock now I have to HOPE they deliver it to where im staying like they said would. International flight crew was very disgruntled and not very friendly.

We will be writing a long, detailed letter to corporate about our awful experience with American airlines.

It took way too long to diagnose and solve the problem of a broken crew member cabin seat. Though compensation for the volunteer who left the flight was very kind.

The entertainment package was vast and the selections were very current. Keep updating it was great.

Seats were new and comfortable. Staff was fine. Missed my connection due to weather -which wasn’t their fault- but got no help at all. Gate staff sent me to customer service, which was and stayed unstaffed. Sign with QR code directed me to call or chat. Chat was useless. Call was returned after an hour. No itinerary offered by Frontier could get me home in less than 30 hours. Rebooked with another airline and got a partial refund that came to about 10 percent of what I paid to get home.

What I expected, nickeled and dined and a frontier flight attendant loudly complained about her job and lack of communication as she headed to the gate on her cell phone. Not professional.

I’m not gonna fly Frontier Airlines because booking is not an option. No water or food is for high price, not equipped for health emergency incompetent crew for emergency services. Cheap airline shows it is cheaper in all service categories. Boarding is the best of all airlines!

Very bad! No good service delayed my second connection flight

Frontier is terrible. Paid for exit row, not given exit row, refused to refund fee.

2 hour delay due to late plane, wrong size plane causing overbooking, and people getting off and on the plane after boarding was completed.

The worst. We never made our connection and they did absolutely nothing to help us at the airport.

I never got to experience the flight because they delayed my first flight and I missed this one. Then Frontier didn't want to help me rebook a flight to get me to my final destination.

The Boarding process in Denver was chaotic, and since the line was so long, we were lined up very far from the gate. If there were any announcements from the gate staff, we didn't hear them. The flight attendants were spectacular. The only negative part of the flight was sitting by a 2 1/2 year old who was unruly and unfortunately had parents that matched his behaviors. Also, the restaurants in Denver on the E concourse, they didn't have food (passengers could only order 1 item on the entire menu) or the restaurants had 12-14 people waiting for orders to be prepared and another 6 people waiting to order. If you have a layover in Denver and need to grab food, be prepared to visit the shops with pre-packaged sandwiches, or you can visit another concourse but it may take a while to transit throughout the airport.

Everything went as planned. Crew was great. Seats were still not that comfortable.

Everything you need to know for your flight from Denver to South Carolina

Information on your arrival and departure airports

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