$89 Find Cheap Flights from Denver to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to South Carolina departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Denver to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Denver to South Carolina, as well as popular online travel agencies
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Cheap Flights from Denver to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$257
Myrtle Beach
Myrtle Beach1 stop$256
Greenville
Greenville1 stop$269
Columbia
Columbia1 stop$269
Florence
Florence1 stop$461
Charlotte
Charlotte1 stop$146
Charleston
Charleston1 stop$257
Myrtle Beach
Myrtle Beach1 stop$256
Greenville
Greenville1 stop$269
Columbia
Columbia1 stop$269
Florence
Florence1 stop$461
Charlotte
Charlotte1 stop$146

Book Cheap Denver to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to South Carolina

Wed, Oct 1 - Sun, Oct 5
Frontier Logo
6:55 pm - 8:11 amDEN-CLT
11h 16m1 stop
Frontier Logo
5:20 pm - 7:07 pmCLT-DEN
3h 47mnonstop
$146Frontier
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Thu, Oct 30 - Sun, Nov 2
Frontier Logo
12:16 am - 9:02 amDEN-CLT
6h 46m1 stop
Frontier Logo
6:07 pm - 8:01 pmCLT-DEN
3h 54mnonstop
$147Frontier
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Wed, Oct 1 - Sun, Oct 5
American Airlines Logo
11:59 pm - 5:05 amDEN-CLT
3h 06mnonstop
American Airlines Logo
7:21 am - 8:56 amCLT-DEN
3h 35mnonstop
$177American Airlines
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Sun, Sep 21 - Sat, Sep 27
American Airlines Logo
11:59 pm - 5:04 amDEN-CLT
3h 05mnonstop
American Airlines Logo
8:35 pm - 10:07 pmCLT-DEN
3h 32mnonstop
$187American Airlines
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Tue, Oct 21 - Tue, Oct 28
Delta Logo
7:00 am - 3:09 pmDEN-CHS
6h 09m1 stop
Delta Logo
8:10 am - 11:45 amCHS-DEN
5h 35m1 stop
$257Delta
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Mon, Sep 15 - Sat, Sep 20
United Airlines Logo
11:54 pm - 10:39 amDEN-MYR
8h 45m1 stop
United Airlines Logo
3:45 pm - 5:41 pmMYR-DEN
3h 56mnonstop
$259United Airlines
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Mon, Sep 15 - Sat, Sep 20
Delta Logo
12:45 am - 10:44 amDEN-CHS
7h 59m1 stop
Delta Logo
3:20 pm - 7:54 pmCHS-DEN
6h 34m1 stop
$262Delta
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Fri, Sep 26 - Tue, Sep 30
United Airlines Logo
1:40 pm - 11:43 pmDEN-CHS
8h 03m1 stop
United Airlines Logo
4:20 pm - 6:03 pmCHS-DEN
3h 43mnonstop
$266United Airlines
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Tue, Oct 28 - Thu, Oct 30
Southwest Logo
10:20 am - 7:55 pmDEN-GSP
7h 35m1 stop
Southwest Logo
8:25 am - 3:15 pmGSP-DEN
8h 50m2 stops
$274Southwest
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Fri, Nov 7 - Wed, Nov 12
Southwest Logo
5:10 am - 2:20 pmDEN-SAV
7h 10m1 stop
Southwest Logo
7:50 am - 12:45 pmSAV-DEN
6h 55m2 stops
$290Southwest
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Booking Insights

KAYAK's insights & trends for Denver to South Carolina flights

Get data-powered insights and trends into flights from Denver to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Denver to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Denver found in the last 72 hours was to Charleston, at $255 round-trip. The most popular route is from Denver (DEN) to Charleston (CHS), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $255.

Can I save money by flying with a layover from Denver to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 2 stops layover the cheapest option at $553 on average.

What is the cheapest month to fly from Denver to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Denver to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Denver to South Carolina is January, when tickets cost $347 (return) on average. On the other hand, the most expensive months are December and March, when the average cost of round-trip tickets is $569 and $489 respectively.

What’s the cheapest day of the week to fly from Denver to South Carolina?

The average price of all round-trip flights from Denver to South Carolina clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to South Carolina on a Tuesday and more expensive on a Sunday. On your return trip to Denver, you should consider flying back on a Tuesday, and avoid Mondays for better deals.

How far in advance should I book a flight from Denver to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Denver to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Denver to South Carolina, you should book around 5 weeks before departure, which saves you about 53% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 26 weeks before departure.

Good to know

Low seasonFebruary
Cheapest flight$89
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly and prices are also 7% lower on average.
Flight from Denver to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Denver to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Denver to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Denver to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Denver to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Denver to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Denver to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Denver to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Denver to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally in the evening, when round-trip flights cost $449 on average. Morning departures are around 16% more expensive than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the morning, which is peak travel time and where the average cost of a ticket is $522.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Denver to the following destinations at these prices or less: Charlotte $135 one-way - $259 round-trip

Reviews of the top 5 airlines serving from Denver to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Denver to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Denver to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4243 reviews
8.6Crew
8.0Comfort
7.5Entertainment
8.1Boarding
7.0Food
Airline reviews

AC sub par. WiFi not working correctly. Ac sucked. Seats very narrow.

2.0 MediocreMike, Aug 2025AUS - BWI
Read more Southwest reviews

AC sub par. WiFi not working correctly. Ac sucked. Seats very narrow.

Near 4 hour flight with only 1 service. Had to use call button to request water. Internet and power not working until into flight. Internet would stop working during flight.

Southwest's seats are the least comfortable I have ever sat in.

The cabin was quiet for the redeye flight. The area was clean. The staff was great. The 787 Max was in good condition. Drawbacks were that the seat widths were tight for some passengers. The seat padding was at best average and for a long flight uncomfortable.

Southwest like most American domestic airlines, is a mediocre airline. But it is among the cheapest. Oh well.

My flight was delayed 50 minutes and we were rushed to board to then sit for 15 minutes until the pilot arrived. Unacceptable since we could have waited to board. Also the delayed flight was updated AFTER we boarded to more than the 10 minutes as originally stated.

Other than a bit of a delay, everything was good. Again, the boarding process and picking seats is the only thing I don't enjoy.

If we are going to have to pay for luggage, make it easier to do. Put something on the app during check-in so I don't need to do it at the kiosk. I've done it twice recently and I ended up having to pay at the desk because something went wrong at the kiosk in Tampa.

southwest just starting charging for luggage. hadnt realized it until it was too late. now out $70 when i couldve bought a carry on if i wouldve known. free bags was one of the only reasons i chose southwest over another airline (the other being no assigned seats, which is apparently also being changed). stupid business decision. wont be flying southwest anymore.

The quality of Southwest Airlines continues to degrade each time I fly with them. If it were not for the free luggage, I would probably choose another airline. Their prices are a little bit competitive, but way too high for the quality of the service. Southwest is not unique in this way. Domestic flight in the United States of America has continued to be a lower and lower quality product. Very sad when you compare the quality of domestic airlines to that of many international airlines around the world.

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

Mechanic delay in addition to a 2 hour change in takeoff time was frustrating.

Delayed due to thunderstorms and no in-flight service due to rough weather — both of which are out of Delta’s control. Flight was good overall.

The flight attendants in SLC were rude. I arrived 40 minutes early to gate. Ticket said I needed check in for seat assignments and tried check in and attendants said they weren’t doing it. And proceeded to never call me to give me a ticket so when time to board I received the very last seat. Please relay to employees to do their job better..,

On this flight I felt the food offering was not as complete as on previous flights. The tomato salad was a bit off and there was nothing additional such a bread or butter. The breakfast was only one option, so you either ate what they had or ate nothing. The crew was efficient, but most seemed frustrated throughout the flight. The flight arrived early and was obstacle-free, so I’m overall quite happy, but the shine in the rest of the experience just wasn’t there.

The seats got pretty uncomfortable pretty fast. The armrests are bigger than on other planes, so I had less room in the actual seat. My butt hurt by the end of the flight. :/ comfort was the primary issue. The crew were fantastic!

I believe that a four-hour trip should have a meal. Delta had none.

Great flight with Delta! Boarding was quick and easy, the amenities were solid, and the plane was in great shape. The flight attendants had a fun, lively energy while staying professional. All in all, a smooth trip — even managed to catch up on some rest. Thanks, Delta!

I was uncomfortably cold on the plane. Other than that it was uneventful and therefore as enjoyable as a plane ride can be.

Impressed with the service despite turbulence because of the weather. Both flights arrived before their scheduled times.

Great experience…left a bit behind schedule but made up fir that in the air and landed 10 minutes early 😁

Electric plugs didn't work. Entertainment system wasn't working

The design of the light switch on the arm rest is ridiculous.

The gate attendant let me walk right by her with a bag too big for the overhead compartment

Overall, it was a good experience. Boarding was good and there was plenty of overhead bin space for everyone’s carryons (even when we boarded toward the end). Only improvement would be to offer trash service more regularly.

David went above and beyond to make our flight the best that it could be

No food service almost missed because of first flight delays

Had a hard time finding my assigned seat. No attendants to assist.

The negative was the wait at the airport coming back. I checked my bags in, an hour before boarding and I get the notification that my flight was delayed. Rather had gotten the notification while I was at the hotel. Then it was delayed 3 x’s. Ugh!

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

The AA staff person who checked our bags was curt and almost rude. The FA also seemed unhappy doing her job. Overall it was like riding the school bus back in grade school.

Internet was a bit expensive and did not work ask that week otherwise a good flight

Ring in first class for an overnight flight, there was no blankets nor pillows for first class customers.

My Internet did not work for Outlook email or basically anything. I paid for one hour of in-flight usage and it was terrible. I spent a lot of time on different sites and browsers with no luck and a lot of frustration. Other than that, the flight was on time, crew was nice, service was fine. Seat was OK even though I paid for the extra 6 inches. I cannot imagine how tight the seats in the back must be.

Delayed flight that lead to a missed connection and a 5-hour trip became a 12-hour flight 🙄

Any flight to ORD after about 2pm this summer has been challenging. Flight was delayed getting in (coming from ORD) and that led to it not leaving before a ground stop due to lightening before they could fuel the plane, and so forth. They made up some time but we were still late in arriving at ORD, and that led to missed connections.

Food was ok, but not as good as I have had before on AA.

No issues. They did change our gate FOUR times in about 30 minutes which was mildly annoying but the flight was fine.

Great flight. No issues at all. I still think boarding could be more efficient but otherwise, a good experience.

What I expected, nickeled and dined and a frontier flight attendant loudly complained about her job and lack of communication as she headed to the gate on her cell phone. Not professional.

I’m not gonna fly Frontier Airlines because booking is not an option. No water or food is for high price, not equipped for health emergency incompetent crew for emergency services. Cheap airline shows it is cheaper in all service categories. Boarding is the best of all airlines!

Very bad! No good service delayed my second connection flight

Frontier is terrible. Paid for exit row, not given exit row, refused to refund fee.

2 hour delay due to late plane, wrong size plane causing overbooking, and people getting off and on the plane after boarding was completed.

The worst. We never made our connection and they did absolutely nothing to help us at the airport.

I never got to experience the flight because they delayed my first flight and I missed this one. Then Frontier didn't want to help me rebook a flight to get me to my final destination.

The Boarding process in Denver was chaotic, and since the line was so long, we were lined up very far from the gate. If there were any announcements from the gate staff, we didn't hear them. The flight attendants were spectacular. The only negative part of the flight was sitting by a 2 1/2 year old who was unruly and unfortunately had parents that matched his behaviors. Also, the restaurants in Denver on the E concourse, they didn't have food (passengers could only order 1 item on the entire menu) or the restaurants had 12-14 people waiting for orders to be prepared and another 6 people waiting to order. If you have a layover in Denver and need to grab food, be prepared to visit the shops with pre-packaged sandwiches, or you can visit another concourse but it may take a while to transit throughout the airport.

Everything went as planned. Crew was great. Seats were still not that comfortable.

they delayed my flight which ended up, causing my layover flight to leave without me, resulting in me missing a flight and having to stay overnight in Houston international. I got no compensation other than a flight to my original location only a day later. i’ve never experienced such a unprofessional situation

Everything you need to know for your flight from Denver to South Carolina

Information on your arrival and departure airports

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