DEN - FLO

$399 Find Cheap Flights from Denver to Florence - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$385
Typical prices: $479-$708
American Airlines
Sat 12/1Sat 12/8
DEN - FLO • 1 stop
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Booking Insights
Flight Deals

Cheap Flights from Denver to Florence (DEN-FLO)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to Florence

Tue, Dec 1 - Tue, Dec 8
American Airlines Logo
4:07 pm - 11:54 pmDEN  Denver Intl-FLO Florence
5h 47m1 stop Charlotte Douglas
American Airlines Logo
3:44 pm - 9:58 pmFLO  Florence-DEN Denver Intl
8h 14m1 stop Charlotte Douglas
$385American Airlines
Sun, Nov 29 - Sun, Dec 6
American Airlines Logo
5:00 am - 2:09 pmDEN  Denver Intl-FLO Florence
7h 09m1 stop Charlotte Douglas
American Airlines Logo
5:05 am - 9:22 amFLO  Florence-DEN Denver Intl
6h 17m1 stop Charlotte Douglas
$399American Airlines
Tue, Dec 1 - Tue, Dec 8
American Airlines Logo
4:07 pm - 11:54 pmDEN  Denver Intl-FLO Florence
5h 47m1 stop Charlotte Douglas
American Airlines Logo
3:44 pm - 8:17 amFLO  Florence-DEN Denver Intl
18h 33m2 stops Charlotte Douglas Dallas/Fort Worth
$443American Airlines
Mon, Nov 30 - Sat, Dec 12
American Airlines Logo
6:20 am - 2:09 pmDEN  Denver Intl-FLO Florence
5h 49m1 stop Charlotte Douglas
American Airlines Logo
6:24 am - 10:25 amFLO  Florence-DEN Denver Intl
6h 01m1 stop Charlotte Douglas
$487American Airlines
Mon, Nov 30 - Sat, Dec 12
American Airlines Logo
4:07 pm - 11:54 pmDEN  Denver Intl-FLO Florence
5h 47m1 stop Charlotte Douglas
American Airlines Logo
6:24 am - 7:54 pmFLO  Florence-DEN Denver Intl
15h 30m2 stops Charlotte Douglas Dallas/Fort Worth
$504American Airlines
Wed, Dec 2 - Tue, Dec 8
American Airlines Logo
3:42 pm - 10:55 pmDEN  Denver Intl-FLO Florence
5h 13m1 stop Charlotte Douglas
American Airlines Logo
3:44 pm - 9:58 pmFLO  Florence-DEN Denver Intl
8h 14m1 stop Charlotte Douglas
$505American Airlines
Sun, Nov 29 - Wed, Dec 9
American Airlines Logo
5:00 am - 2:09 pmDEN  Denver Intl-FLO Florence
7h 09m1 stop Charlotte Douglas
American Airlines Logo
6:24 am - 10:10 amFLO  Florence-DEN Denver Intl
5h 46m1 stop Charlotte Douglas
$529American Airlines
Tue, Dec 1 - Tue, Dec 8
American Airlines Logo
9:03 am - 11:54 pmDEN  Denver Intl-FLO Florence
12h 51m2 stops Dallas/Fort Worth Charlotte Douglas
American Airlines Logo
3:44 pm - 12:23 pmFLO  Florence-DEN Denver Intl
22h 39m2 stops Charlotte Douglas Dallas/Fort Worth
$565American Airlines
Sun, Nov 29 - Sun, Dec 6
American Airlines Logo
5:00 am - 2:09 pmDEN  Denver Intl-FLO Florence
7h 09m1 stop Charlotte Douglas
American Airlines Logo
5:05 am - 3:33 pmFLO  Florence-DEN Denver Intl
12h 28m2 stops Charlotte Douglas Dallas/Fort Worth
$573American Airlines
Sun, Nov 29 - Sat, Dec 12
American Airlines Logo
5:00 am - 2:09 pmDEN  Denver Intl-FLO Florence
7h 09m1 stop Charlotte Douglas
American Airlines Logo
6:24 am - 10:25 amFLO  Florence-DEN Denver Intl
6h 01m1 stop Charlotte Douglas
$596American Airlines
Booking Insights

Price, demand and travel trends for Denver to Florence flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Denver to Florence?

Round-trip flights from Denver to Florence typically range from $479 to $708. The lowest price found in the past 5 days was $385, on American Airlines.

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Key details for Denver to Florence flights

Cheapest flight

$385
Round-trip flight from Denver to Florence

When to book flights from Denver to Florence

Are your dates flexible? Find out the best times to travel from Denver to Florence based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Denver to Florence flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Denver to Florence?

    Only Economy Class is available on flights from Denver to Florence.

  • Do I need a passport to fly from Denver to Florence?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • Have flight prices from Denver to Florence changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $385 to $1,315. That means the highest observed fare was about 3x higher than the lowest one.

  • What car rental options are available at Florence Airport (FLO)?

    Florence Airport (FLO) hosts 5 major car rental companies, with daily rates averaging $94 for economy cars. Top options include:

    • Budget
    • Avis
    • Enterprise Rent-A-Car
    • Alamo
    • Skylimit Srl

  • Which airports can I use when flying from Denver to Florence?

    Flights from Denver to Florence usually depart from Denver Intl (DEN) and arrive at Florence (FLO).

  • Which airports do connecting flights from Denver to Florence pass through?

    Most connecting flights from Denver to Florence pass through Charlotte Douglas (CLT), which handles 100% of one-stop traffic on this route.

  • Can I save money by using flexible dates for flights from Denver to Florence?

    Yes. Flexible dates can save you up to 33% on flights from Denver to Florence. Wednesday is the cheapest departure day at $479 round-trip on average, while Thursday is the most expensive at $708, a difference of $229.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What is the time difference between Denver and Florence?

    Florence is 2 hours ahead of Denver (Eastern Time vs Mountain Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking Denver to Florence flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Thursday. On this route, Wednesday flights average $479, about $229 less than Thursday fares (32% savings) based on the last 12 months.

More options for your flight from Denver to Florence

Complete your trip to Florence with a hotel stay or car rental

Car rentals in Florence
Hotels in Florence
Vacations in Florence