DSM - MDT

$208 Find Cheap Flights from Des Moines to Harrisburg - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$349
Typical prices: $353-$558
American Airlines
Wed 12/5Wed 12/12
DSM - MDT • 1 stop
Cheapest one-way
$208
Typical prices: $292-$418
Allegiant Air
Sun 1/28
DSM - MDT • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Harrisburg. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
December
Cheapest • 13% price drop
June
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Chicago O'Hare Intl (ORD)
Cheapest • Avg $475 (round-trip)
Detroit Metropolitan Wayne County (DTW)
Shortest trip • 4h 39m (one-way)
Insights
Insights
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Booking Insights
Flight Deals

Cheap Flights from Des Moines to Harrisburg (DSM-MDT)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Harrisburg

Sat, Dec 5 - Sat, Dec 12
American Airlines Logo
9:23 am - 2:47 pmDSM  Des Moines-MDT Harrisburg
4h 24m1 stop Chicago O'Hare Intl
American Airlines Logo
12:04 pm - 7:01 pmMDT  Harrisburg-DSM Des Moines
7h 57m1 stop Chicago O'Hare Intl
$349American Airlines
Sat, Dec 5 - Sat, Dec 12
United Airlines Logo
1:15 pm - 6:43 pmDSM  Des Moines-MDT Harrisburg
4h 28m1 stop Chicago O'Hare Intl
United Airlines Logo
6:17 am - 4:13 pmMDT  Harrisburg-DSM Des Moines
10h 56m2 stops Chicago O'Hare Intl Denver Intl
$354United Airlines
Sat, Dec 5 - Sat, Dec 12
American Airlines Logo
2:05 pm - 11:10 pmDSM  Des Moines-MDT Harrisburg
8h 05m2 stops Chicago O'Hare Intl Boston Logan Intl
American Airlines Logo
9:56 am - 7:01 pmMDT  Harrisburg-DSM Des Moines
10h 05m2 stops Philadelphia Chicago O'Hare Intl
$359American Airlines
Sat, Jan 23 - Wed, Jan 27
United Airlines Logo
12:52 pm - 7:11 pmDSM  Des Moines-MDT Harrisburg
5h 19m1 stop Chicago O'Hare Intl
United Airlines Logo
5:40 pm - 9:37 pmMDT  Harrisburg-DSM Des Moines
4h 57m1 stop Chicago O'Hare Intl
$449United Airlines
Sat, Jan 23 - Wed, Jan 27
United Airlines Logo
8:00 am - 1:32 pmDSM  Des Moines-MDT Harrisburg
4h 32m1 stop Chicago O'Hare Intl
United Airlines Logo
6:20 am - 10:41 amMDT  Harrisburg-DSM Des Moines
5h 21m1 stop Chicago O'Hare Intl
$449United Airlines
Wed, Dec 23 - Wed, Dec 30
United Airlines Logo
5:00 am - 1:35 pmDSM  Des Moines-MDT Harrisburg
7h 35m1 stop Chicago O'Hare Intl
United Airlines Logo
6:03 am - 10:46 amMDT  Harrisburg-DSM Des Moines
5h 43m1 stop Chicago O'Hare Intl
$453United Airlines
Sat, Jan 23 - Wed, Jan 27
United Airlines Logo
9:25 am - 4:59 pmDSM  Des Moines-MDT Harrisburg
6h 34m1 stop Chicago O'Hare Intl
United Airlines Logo
6:20 am - 3:51 pmMDT  Harrisburg-DSM Des Moines
10h 31m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
$454United Airlines
Wed, Dec 23 - Wed, Dec 30
American Airlines Logo
6:16 pm - 12:12 amDSM  Des Moines-MDT Harrisburg
4h 56m1 stop Charlotte Douglas
American Airlines Logo
5:00 am - 9:12 amMDT  Harrisburg-DSM Des Moines
5h 12m1 stop Chicago O'Hare Intl
$543American Airlines
Mon, Nov 30 - Fri, Dec 4
Allegiant Air Logo
1:26 pm - 8:28 pmDSM  Des Moines-MDT Harrisburg
6h 02m1 stop Orlando Sanford Intl
Allegiant Air Logo
8:59 pm - 12:09 pmMDT  Harrisburg-DSM Des Moines
16h 10m1 stop Orlando Sanford Intl
$592Allegiant Air
Mon, Nov 30 - Fri, Dec 4
Multiple Airlines Logo
1:26 pm - 8:28 pmDSM  Des Moines-MDT Harrisburg
6h 02m1 stop Orlando Sanford Intl
Multiple Airlines Logo
6:55 pm - 4:46 pmMDT  Harrisburg-DSM Des Moines
46h 51m2 stops Tampa St. Petersburg Fort Lauderdale
$813Multiple Airlines
Booking Insights

Price, demand and travel trends for Des Moines to Harrisburg flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Des Moines to Harrisburg?

Round-trip flights from Des Moines to Harrisburg typically range from $353 to $558. The lowest price found in the past 5 days was $349, on American Airlines.

What's the cheapest day of the week to fly from Des Moines to Harrisburg?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Des Moines to Harrisburg. It’s 12% cheaper than the average day, while Monday is the most expensive, with prices 109% higher.

What’s the cheapest month to fly from Des Moines to Harrisburg?

•December is the cheapest month to fly from Des Moines to Harrisburg at $353 round-trip.
•March ($646) and September ($592) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 83% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Des Moines to Harrisburg flights

Low season

January

Cheapest flight

$208
Beat the crowds with an average 56% drop in travelers.
The most popular month to fly with an average 76% increase in travelers.
One-way flight from Des Moines to Harrisburg

When to book flights from Des Moines to Harrisburg

Are your dates flexible? Find out the best times to travel from Des Moines to Harrisburg based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Des Moines to Harrisburg flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Des Moines to Harrisburg?

    Two cabin classes are available on flights from Des Moines to Harrisburg:

    • Economy Class
    • First Class

  • How long is a flight from Des Moines to Harrisburg?

    A nonstop flight from Des Moines to Harrisburg takes 00m, covering 886 miles.

  • Do I need a passport to fly from Des Moines to Harrisburg?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Des Moines to Harrisburg flight?

    Round-trip flights from Des Moines to Harrisburg range from $353 to $558, with an average of $406 over the past 12 months. Anything below $353 counts as a good deal.

  • Have flight prices from Des Moines to Harrisburg changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $349 to $937. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from Des Moines to Harrisburg looking right now?

    One-way fares from Des Moines to Harrisburg are currently lower than usual. Average one-way flight prices are about $342, which is 17% below the typical average for this route.

  • What car rental options are available at Harrisburg Airport (MDT)?

    Harrisburg Airport (MDT) hosts 5 major car rental companies, with daily rates averaging $71 for economy cars. Top options include:

    • Hertz
    • Alamo
    • Budget
    • Enterprise Rent-A-Car
    • National

  • Which airports can I use when flying from Des Moines to Harrisburg?

    Flights from Des Moines to Harrisburg usually depart from Des Moines (DSM) and arrive at Harrisburg (MDT).

  • Which airports do connecting flights from Des Moines to Harrisburg pass through?

    One-stop flights from Des Moines to Harrisburg most commonly connect through:

    • Chicago O'Hare Intl (ORD) - 81% of one-stop connections
    • Detroit Metropolitan Wayne County (DTW) - 13% of one-stop connections
    • Philadelphia (PHL) - 3% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 1% of one-stop connections

  • Can I save money by using flexible dates for flights from Des Moines to Harrisburg?

    Yes. Flexible dates can save you up to 58% on flights from Des Moines to Harrisburg. Tuesday is the cheapest departure day at $361 round-trip on average, while Monday is the most expensive at $851, a difference of $490.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Des Moines to Harrisburg?

    Flying via Detroit Metropolitan Wayne County (DTW) gives the shortest average 1-stop total travel time at 4h 39m, compared with 4h 40m via Charlotte Douglas (CLT) and 5h 03m via Atlanta Hartsfield-Jackson (ATL).

  • What is the time difference between Des Moines and Harrisburg?

    Harrisburg is 1 hour ahead of Des Moines (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking Des Moines to Harrisburg flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Monday. On this route, Tuesday flights average $361, about $490 less than Monday fares (58% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Des Moines to Harrisburg trip for December. Fares historically average $353 round-trip in that month - typically $293 less than the most expensive month, which is March (based on the last 12 months).

More options for your flight from Des Moines to Harrisburg

Complete your trip to Harrisburg with a hotel stay or car rental

Car rentals in Harrisburg
Hotels in Harrisburg
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