DSM - MDT

$269 Find Cheap Flights from Des Moines to Harrisburg

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Harrisburg departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Harrisburg

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Harrisburg, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Harrisburg, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$309
Typical prices: $335-$372
American Airlines
Mon 8/31Sun 9/6
DSM - MDT • 1 stop
Cheapest one-way
$269
American Airlines
Fri 10/30
DSM - MDT • 1 stop
Top airlines
Cheapest • from $309 (round-trip)
Best reviews • 7.8 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Harrisburg. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $365 (round-trip)
Shortest trip • 4h 36m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 37% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Harrisburg!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Harrisburg (DSM-MDT)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Harrisburg that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Harrisburg

Mon, Aug 31 - Sun, Sep 6
American Airlines Logo
1:55 pm - 9:58 pm
DSM
-
MDT
7h 03m
1 stop
American Airlines Logo
7:31 pm - 12:20 am
MDT
-
DSM
5h 49m
1 stop
$309American Airlines
Mon, Aug 31 - Sun, Sep 6
American Airlines Logo
5:40 am - 1:58 pm
DSM
-
MDT
7h 18m
1 stop
American Airlines Logo
6:20 am - 1:25 pm
MDT
-
DSM
8h 05m
2 stops
$314American Airlines
Fri, Jul 31 - Sun, Aug 2
American Airlines Logo
6:33 pm - 12:22 am
DSM
-
MDT
4h 49m
1 stop
American Airlines Logo
7:45 pm - 12:01 am
MDT
-
DSM
5h 16m
1 stop
$388American Airlines
Thu, Jul 2 - Sat, Jul 4
American Airlines Logo
1:04 pm - 6:57 pm
DSM
-
MDT
4h 53m
1 stop
American Airlines Logo
11:41 am - 5:43 pm
MDT
-
DSM
7h 02m
1 stop
$414American Airlines
Thu, Jul 2 - Sat, Jul 4
American Airlines Logo
1:04 pm - 6:57 pm
DSM
-
MDT
4h 53m
1 stop
American Airlines Logo
10:15 am - 5:43 pm
MDT
-
DSM
8h 28m
2 stops
$419American Airlines
Thu, Jul 2 - Sat, Jul 4
American Airlines Logo
1:35 pm - 11:10 pm
DSM
-
MDT
8h 35m
2 stops
American Airlines Logo
10:15 am - 5:43 pm
MDT
-
DSM
8h 28m
2 stops
$425American Airlines
Mon, Aug 10 - Sat, Aug 15
American Airlines Logo
6:55 am - 12:45 pm
DSM
-
MDT
4h 50m
1 stop
American Airlines Logo
1:25 pm - 7:14 pm
MDT
-
DSM
6h 49m
1 stop
$429American Airlines
Fri, Jul 31 - Sun, Aug 2
American Airlines Logo
6:33 pm - 12:22 am
DSM
-
MDT
4h 49m
1 stop
American Airlines Logo
7:45 pm - 8:13 am
MDT
-
DSM
13h 28m
1 stop
$448American Airlines
Fri, Jul 24 - Fri, Jul 31
Allegiant Air Logo
5:30 pm - 3:19 pm
DSM
-
MDT
44h 49m
2 stops
Allegiant Air Logo
11:37 am - 4:40 pm
MDT
-
DSM
6h 03m
1 stop
$462Allegiant Air
Fri, Jul 10 - Tue, Jul 14
United Airlines Logo
3:24 pm - 9:29 pm
DSM
-
MDT
5h 05m
1 stop
United Airlines Logo
5:55 pm - 10:56 pm
MDT
-
DSM
6h 01m
1 stop
$464United Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Harrisburg flights

Get data-powered insights and trends into flights from Des Moines to Harrisburg to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Des Moines to Harrisburg?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to Harrisburg departing in August.

What is the cheapest month to fly from Des Moines to Harrisburg?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Harrisburg, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Harrisburg is October, where tickets cost $268 (return) on average. On the other hand, the most expensive months are March and July, where the average cost of round-trip tickets is $646 and $503 respectively.

Good to know

Low seasonFebruary
Cheapest flight$269
Best time to beat the crowds but there is an average 17% increase in price.
Most popular time to fly and prices are also 37% lower on average.
Flight from Des Moines to Harrisburg

When to book flights from Des Moines to Harrisburg

Are your dates flexible? Find out the best times to travel from Des Moines to Harrisburg based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Harrisburg

  • What is the cheapest flight from Des Moines to Harrisburg?

    In the last 5 days, the lowest price for a flight from Des Moines to Harrisburg was $269 for a one-way ticket and $309 for a round-trip.

  • Do I need a passport to fly between Des Moines and Harrisburg?

    A passport is not required to fly from Des Moines to Harrisburg.

  • Which airports will I be using when flying from Des Moines to Harrisburg?

    On your way to Harrisburg, you’ll fly out from Des Moines. You’ll be landing at Harrisburg.

  • Which aircraft models fly most regularly from Des Moines to Harrisburg?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Harrisburg?

    SkyTeam, Star Alliance, and oneworld are the airline alliances operating flights between Des Moines and Harrisburg, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Harrisburg, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Harrisburg are Delta and United Airlines. With an average price for the route of $518 and an overall rating of 7.8, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $397 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Des Moines to Harrisburg?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Harrisburg.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Harrisburg?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Harrisburg from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Harrisburg?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Harrisburg with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and MDT can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Harrisburg?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Harrisburg from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Des Moines to Harrisburg

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Harrisburg. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Harrisburg? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8455 reviews
8.1Boarding
8.5Crew
7.8Entertainment
7.8Comfort
7.2Food
Airline reviews

Only beverages were offered to first class and I thought the flight attendant could have also served the Delta Comfort as well instead of sitting down and staring at her phone and walking past all of us to the back of the plane to charge her phone more. There was a complete lack of turbulence and was safe enough for flights attendant to walk around in the front of the plane, collect trash and serve a few people water and turn off the seat belt light. Also didn’t enforce people putting their seats into the upright position and allowed two passengers to remain reclined during landing. They seemed out to lunch completely. Usually my experience on Delta is much better.

4.0 OkayMichelle, Jun 2026
ATL - PIT
Read more Delta reviews

Only beverages were offered to first class and I thought the flight attendant could have also served the Delta Comfort as well instead of sitting down and staring at her phone and walking past all of us to the back of the plane to charge her phone more. There was a complete lack of turbulence and was safe enough for flights attendant to walk around in the front of the plane, collect trash and serve a few people water and turn off the seat belt light. Also didn’t enforce people putting their seats into the upright position and allowed two passengers to remain reclined during landing. They seemed out to lunch completely. Usually my experience on Delta is much better.

My tray was broken so i had no place to work or eat except my lap. Flight attendant said I would get an email with some credit or miles, it was a complete waste of time as I could only function at about 20% of normal. I have not received anything yet.

Delayed. Hot. Passenger next to me was so large I couldn’t move.

2+hrs delay without any reason provided and a cramped flight

Originally, I was booked in economy. I paid several hundred additional dollars to upgrade to first class. Then I paid several more hundred dollars to change my flight to a slightly earlier flight. I asked if the changed flight would also seat me in first class, and I was told that it would. When I boarded the plane, however, I was seated in economy. So, I paid $500-600 more than I paid for my original ticket for an upgrade and a changed flight - received the changed flight (which was nice), but did not receive the upgrade. So, I was not completely satisfied.

I noticed that the planes seem to be outdated. There was no entertainment per se. Also, the waiting area did not have any working electrical outlets

Delayed due to thunderstorms and no in-flight service due to rough weather — both of which are out of Delta’s control. Flight was good overall.

This was the second flight this week with flight attendant Marcus I’m not sure if his last name is Lane or Lang but this guy is awesome. He funny, attentive and his service is 5 stars. Marcus makes business travel more enjoyable !

My seat was moved closer to the front of the cabin since I had requested wheelchair assistance to the gate.

Made the Atlanta to Pittsburgh trip many times, with Delta no issues

1 flight cancelled Had to fly out of different city Flight at new departure city was delayed 3 hours causing us to miss connecting flights. By the time we did make it to Prague our luggage did not. Had to wait day and a half for luggage to be delivered. Customer service was not good. Agents did not arrive at gate until 5-10 minutes before boarding

It was better than excellent. The staff in Mason City were great. The young woman that pushed my wheelchair did more than could be expected of her. She came from India 17 years ago. I don't remember her name.

United didn’t even try to hold the flight for me. They knew I had a tight connection and when I arrived at the gate less than 10 mins after final boarding the flight had already gone. The gate agent wasn’t even notified that I was on my way. She was told I wasn’t at the airport

Everything went well except the turbulence what no one have a control of but pilot and crew handled very good!

Very rough getting into denver. my kid threw up it was so rough.

Liked that we left on time for each flight. Snacks not the best, but we're okay.

I still prefer Delta, but Delta doesn’t fly to State College PA.

This flight was delayed multiple times and eventually canceled around 2-3ish. Original take off time was around 10:30am. By 3, there were no other options out of Houston, so stuck in Houston for from 3pm - 11am the next day.

Nothing bad to say about the actual crew or airline. It was nice to have a complimentary FULL can of soda, as well as a snack. Blankets and earbuds were also provided at no cost for this red eye flight. I especially appreciated the free WiFi and movie selection with the Bluetooth option. It helped the flight pass more quickly. No matter who you fly, boarding and disembarking are always SUCH a pain. As I mentioned, this is on the passengers and not the crew!!

Ok so apparently the new policy on United Airlines is that customers in the main cabin should NEVER be served more than once and besides picking up trash there should NEVER be another interaction with the customer for any reason.

I cancelled this flight 2 days before departure but I followed your texts and emails and IF you were correct this flight turned into a nightmare.

The seats. The seat in front of me was awful and when the guy sat down, it flew back and hit my head when I was putting my backpack under the seat, It didn't make for a pleasant experience,

Cancelled flight. Still waiting to get home for grand daughter’s graduation .

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

Cleared standby and gave up my seat. Terrible policy and boarding experience

Flight was on time is the only good thing. Person loading the plane called 1-6 to board at the same time, made it chaotic. Plane was too small for even putting backpacks in overhead. Seat for normal sized people were too small. The WIFI didn't work. When we landed had to wait because not enough ground crew.

In flight connectivity (via T-Mobile) was often not working.

Terrible. Internet/kiosk glitch prevented baggage checkin. Line at ticket co in Ter was under serviced and did not move. Agents did not call for flight but rather allowed time to pass. Then told each person as they reached the front if line that it was too late to check bags so they’d have to rebook flights. At least 15 people missed the flight as a result of this incompetence.

It was exactly what I expected, actually arriving sooner than scheduled.

Terrible, they canceled my flight due to an issue they had, couldn't fly me into the same place within 24 hrs so had to fly in 2.5 hrs away from my destination and spend even more money. The customer service was terrible (except at the airport in Charleston). Had to call to get my checked baggage fees reimbursed 2 wks later in which one customer service agent was very rude, wouldn't listen and then hung up on me. The second lady I spoke with was actually able to help me with that part thankfully. Would not recommend flying AA.

Everything you need to know for your flight from Des Moines to Harrisburg

Information on your arrival and departure airports