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DSM - MDT

$284 Find Cheap Flights from Des Moines to Harrisburg - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$339
Typical prices: $308-$512
American Airlines
Wed 11/7Fri 11/9
DSM - MDT • 1 stop
Cheapest one-way
$284
Typical prices: $313-$418
American Airlines
Mon 11/26
DSM - MDT • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Harrisburg. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
December
Cheapest • 26% price drop
June
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Orlando Sanford Intl (SFB)
Cheapest • Avg $365 (round-trip)
Detroit Metropolitan Wayne County (DTW)
Shortest trip • 4h 34m (one-way)
Insights
Insights
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Harrisburg (DSM-MDT)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Harrisburg

Sat, Nov 7 - Mon, Nov 9
American Airlines Logo
7:23 am - 2:44 pmDSM  Des Moines-MDT Harrisburg
6h 21m1 stop Chicago O'Hare Intl
American Airlines Logo
7:52 pm - 12:26 amMDT  Harrisburg-DSM Des Moines
5h 34m1 stop Chicago O'Hare Intl
$339American Airlines
Wed, Oct 21 - Sat, Oct 31
Delta Logo
5:50 pm - 10:58 pmDSM  Des Moines-MDT Harrisburg
4h 08m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:13 am - 9:42 amMDT  Harrisburg-DSM Des Moines
4h 29m1 stop Detroit Metropolitan Wayne County
$339Delta
Tue, Oct 13 - Sat, Oct 17
American Airlines Logo
6:00 am - 2:10 pmDSM  Des Moines-MDT Harrisburg
7h 10m1 stop Philadelphia
American Airlines Logo
6:43 am - 12:45 pmMDT  Harrisburg-DSM Des Moines
7h 02m1 stop Philadelphia
$369American Airlines
Tue, Oct 13 - Sat, Oct 17
United Airlines Logo
6:00 am - 1:27 pmDSM  Des Moines-MDT Harrisburg
6h 27m1 stop Chicago O'Hare Intl
United Airlines Logo
2:55 pm - 11:35 pmMDT  Harrisburg-DSM Des Moines
9h 40m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
$374United Airlines
Thu, Oct 22 - Sun, Nov 1
United Airlines Logo
11:27 am - 4:52 pmDSM  Des Moines-MDT Harrisburg
4h 25m1 stop Chicago O'Hare Intl
United Airlines Logo
6:30 am - 10:32 amMDT  Harrisburg-DSM Des Moines
5h 02m1 stop Chicago O'Hare Intl
$388United Airlines
Wed, Oct 21 - Fri, Oct 30
Delta Logo
5:50 pm - 10:58 pmDSM  Des Moines-MDT Harrisburg
4h 08m1 stop Detroit Metropolitan Wayne County
Delta Logo
5:10 pm - 8:40 pmMDT  Harrisburg-DSM Des Moines
4h 30m1 stop Detroit Metropolitan Wayne County
$408Delta
Wed, Oct 21 - Tue, Nov 3
Delta Logo
5:50 pm - 10:58 pmDSM  Des Moines-MDT Harrisburg
4h 08m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:13 am - 9:42 amMDT  Harrisburg-DSM Des Moines
4h 29m1 stop Detroit Metropolitan Wayne County
$408Delta
Thu, Oct 22 - Mon, Nov 2
American Airlines Logo
2:01 pm - 10:19 pmDSM  Des Moines-MDT Harrisburg
7h 18m1 stop Chicago O'Hare Intl
American Airlines Logo
7:52 pm - 12:26 amMDT  Harrisburg-DSM Des Moines
5h 34m1 stop Chicago O'Hare Intl
$439American Airlines
Mon, Oct 19 - Thu, Oct 22
Allegiant Air Logo
6:25 am - 10:30 amDSM  Des Moines-MDT Harrisburg
27h 05m2 stops Nashville Intl Punta Gorda
Allegiant Air Logo
8:51 pm - 8:25 amMDT  Harrisburg-DSM Des Moines
12h 34m1 stop Orlando Sanford Intl
$469Allegiant Air
Sat, Oct 17 - Thu, Oct 22
Allegiant Air Logo
9:00 am - 5:25 pmDSM  Des Moines-MDT Harrisburg
7h 25m1 stop Orlando Sanford Intl
Allegiant Air Logo
8:51 pm - 8:25 amMDT  Harrisburg-DSM Des Moines
12h 34m1 stop Orlando Sanford Intl
$492Allegiant Air
Booking Insights

Price, demand and travel trends for Des Moines to Harrisburg flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Des Moines to Harrisburg?

Round-trip flights from Des Moines to Harrisburg typically range from $308 to $512. The lowest price found in the past 5 days was $339, on American Airlines.

What's the cheapest day of the week to fly from Des Moines to Harrisburg?

Based on deals KAYAK users found in the last 12 months, Saturday is the cheapest day of the week to fly from Des Moines to Harrisburg. It’s 32% cheaper than the average day, while Monday is the most expensive, with prices 115% higher.

What’s the cheapest month to fly from Des Moines to Harrisburg?

•December is the cheapest month to fly from Des Moines to Harrisburg at $291 round-trip.
•March ($646) and January ($558) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 121% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Des Moines to Harrisburg flights

Low season

February

Cheapest flight

$284
Beat the crowds with an average 87% drop in travelers.
The most popular month to fly with an average 119% increase in travelers.
One-way flight from Des Moines to Harrisburg

When to book flights from Des Moines to Harrisburg

Are your dates flexible? Find out the best times to travel from Des Moines to Harrisburg based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Des Moines to Harrisburg flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Des Moines to Harrisburg?

    Two cabin classes are available on flights from Des Moines to Harrisburg:

    • Economy Class
    • First Class

  • How long is a flight from Des Moines to Harrisburg?

    A nonstop flight from Des Moines to Harrisburg takes 00m, covering 886 miles.

  • Do I need a passport to fly from Des Moines to Harrisburg?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Des Moines to Harrisburg flight?

    Round-trip flights from Des Moines to Harrisburg range from $308 to $512, with an average of $394 over the past 12 months. Anything below $308 counts as a good deal.

  • Have flight prices from Des Moines to Harrisburg changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $339 to $1,333. That means the highest observed fare was about 4x higher than the lowest one.

  • How are flight prices from Des Moines to Harrisburg looking right now?

    One-way fares from Des Moines to Harrisburg are currently in line with typical prices for this route. Average one-way fares are about $388.

  • What car rental options are available at Harrisburg Airport (MDT)?

    Harrisburg Airport (MDT) hosts 5 major car rental companies, with daily rates starting from around $32 for economy cars. Top options include:

    • Hertz
    • Alamo
    • Budget
    • Enterprise Rent-A-Car
    • Avis

  • Which airports can I use when flying from Des Moines to Harrisburg?

    Flights from Des Moines to Harrisburg usually depart from Des Moines (DSM) and arrive at Harrisburg (MDT).

  • Which airports do connecting flights from Des Moines to Harrisburg pass through?

    One-stop flights from Des Moines to Harrisburg most commonly connect through:

    • Chicago O'Hare Intl (ORD) - 82% of one-stop connections
    • Detroit Metropolitan Wayne County (DTW) - 12% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 3% of one-stop connections
    • Charlotte Douglas (CLT) - 1% of one-stop connections

  • Can I save money by using flexible dates for flights from Des Moines to Harrisburg?

    Yes. Flexible dates can save you up to 69% on flights from Des Moines to Harrisburg. Saturday is the cheapest departure day at $268 round-trip on average, while Monday is the most expensive at $851, a difference of $583.

    Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

  • How much time can I save by choosing a different layover airport from Des Moines to Harrisburg?

    Flying via Detroit Metropolitan Wayne County (DTW) gives the shortest average 1-stop total travel time at 4h 34m, compared with 4h 40m via Charlotte Douglas (CLT) and 5h 11m via Chicago O'Hare Intl (ORD).

  • What is the time difference between Des Moines and Harrisburg?

    Harrisburg is 1 hour ahead of Des Moines (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking Des Moines to Harrisburg flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Saturday departure and avoid flying on Monday. On this route, Saturday flights average $268, about $583 less than Monday fares (69% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Des Moines to Harrisburg trip for December. Fares historically average $291 round-trip in that month - typically $355 less than the most expensive month, which is March (based on the last 12 months).

More options for your flight from Des Moines to Harrisburg

Complete your trip to Harrisburg with a hotel stay or car rental

Car rentals in Harrisburg
Hotels in Harrisburg
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