DSM - MDT

$269 Find Cheap Flights from Des Moines to Harrisburg

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Harrisburg departing on 4/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Harrisburg

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Harrisburg, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Harrisburg, as well as popular online travel agencies
Travelers love KAYAK
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Everything you should know

Cheapest round-trip
$269
Overall average: $318
Delta
Fri 4/17Tue 4/21
DSM - MDT • 1 stop
Cheapest one-way
$315
Multiple Airlines
Wed 3/4
DSM - MDT • 1 stop
Top airlines
Delta
Cheapest • from $269 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Harrisburg. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Chicago (ORD)
Cheapest • Avg $325 (round-trip)
Detroit (DTW)
Shortest trip • 4h 30m (one-way)
Insights
Insights
Insights
Insights
When to travel
October
Cheapest • 27% price drop
July
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Harrisburg!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Harrisburg (DSM-MDT)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Harrisburg that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Harrisburg

Fri, Apr 17 - Tue, Apr 21
Delta Logo
5:45 pm - 11:03 pm
DSM
-
MDT
4h 18m
1 stop
Delta Logo
4:19 pm - 8:39 pm
MDT
-
DSM
5h 20m
1 stop
$269Delta
Fri, Apr 17 - Mon, Apr 20
American Airlines Logo
5:01 pm - 11:59 pm
DSM
-
MDT
5h 58m
1 stop
American Airlines Logo
6:43 pm - 11:49 pm
MDT
-
DSM
6h 06m
1 stop
$284American Airlines
Fri, Apr 17 - Tue, Apr 21
United Airlines Logo
3:21 pm - 9:18 pm
DSM
-
MDT
4h 57m
1 stop
United Airlines Logo
6:15 am - 12:29 pm
MDT
-
DSM
7h 14m
2 stops
$300United Airlines
Sat, Apr 18 - Tue, Apr 21
United Airlines Logo
1:10 pm - 9:33 pm
DSM
-
MDT
7h 23m
1 stop
United Airlines Logo
8:29 am - 2:25 pm
MDT
-
DSM
6h 56m
1 stop
$339United Airlines
Sat, Apr 18 - Tue, Apr 21
United Airlines Logo
9:00 am - 9:33 pm
DSM
-
MDT
11h 33m
2 stops
United Airlines Logo
6:15 am - 10:44 am
MDT
-
DSM
5h 29m
1 stop
$344United Airlines
Sat, Apr 18 - Mon, Apr 20
United Airlines Logo
9:00 am - 9:33 pm
DSM
-
MDT
11h 33m
2 stops
United Airlines Logo
8:29 am - 2:25 pm
MDT
-
DSM
6h 56m
1 stop
$348United Airlines
Sat, Apr 18 - Tue, Apr 21
United Airlines Logo
1:32 pm - 12:27 am
DSM
-
MDT
9h 55m
2 stops
United Airlines Logo
6:15 am - 12:29 pm
MDT
-
DSM
7h 14m
2 stops
$349United Airlines
Fri, Apr 17 - Tue, Apr 21
United Airlines Logo
9:00 am - 9:18 pm
DSM
-
MDT
11h 18m
2 stops
United Airlines Logo
6:15 am - 4:10 pm
MDT
-
DSM
10h 55m
2 stops
$399United Airlines
Fri, Apr 17 - Mon, Apr 20
United Airlines Logo
9:00 am - 9:18 pm
DSM
-
MDT
11h 18m
2 stops
United Airlines Logo
5:47 pm - 9:27 pm
MDT
-
DSM
4h 40m
1 stop
$416United Airlines
Mon, Apr 20 - Thu, Apr 23
American Airlines Logo
5:01 pm - 11:52 pm
DSM
-
MDT
5h 51m
1 stop
American Airlines Logo
5:38 am - 10:26 am
MDT
-
DSM
5h 48m
1 stop
$417American Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Harrisburg flights

Get data-powered insights and trends into flights from Des Moines to Harrisburg to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Des Moines to Harrisburg?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Harrisburg, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Harrisburg is October, where tickets cost $248 (return) on average. On the other hand, the most expensive months are February and September, where the average cost of round-trip tickets is $497 and $406 respectively.

Good to know

Low seasonNovember
Cheapest flight$269
Best time to beat the crowds but there is an average 7% increase in price.
Most popular time to fly with an average 11% increase in price.
Flight from Des Moines to Harrisburg

When to book flights from Des Moines to Harrisburg

Are your dates flexible? Find out the best times to travel from Des Moines to Harrisburg based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Harrisburg

  • What is the cheapest flight from Des Moines to Harrisburg?

    In the last 3 days, the lowest price for a flight from Des Moines to Harrisburg was $315 for a one-way ticket and $269 for a round-trip.

  • Do I need a passport to fly between Des Moines and Harrisburg?

    A passport is not required to fly from Des Moines to Harrisburg.

  • Which airports will I be using when flying from Des Moines to Harrisburg?

    On your way to Harrisburg, you’ll fly out from Des Moines. You’ll be landing at Harrisburg.

  • Which aircraft models fly most regularly from Des Moines to Harrisburg?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Harrisburg?

    SkyTeam, Star Alliance, and oneworld are the airline alliances operating flights between Des Moines and Harrisburg, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Harrisburg, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Harrisburg are Delta and United Airlines. With an average price for the route of $278 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $353 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Des Moines to Harrisburg?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Harrisburg.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Harrisburg?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Harrisburg from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Harrisburg?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Harrisburg with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and MDT can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Harrisburg?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Harrisburg from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Des Moines to Harrisburg

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Harrisburg. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Harrisburg? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8242 reviews
7.8Entertainment
8.1Boarding
7.2Food
8.5Crew
7.9Comfort
Airline reviews

Everything was good except wifi and a leaking drink chiller. The floor was all wet and my bag was soaked. Did not notice until debarking. Have not heard back from Delta. Even though this was leg one of an international flight in first class, they denied access to their Sky Club - very disappointing!

6.0 GoodAnonymous, Feb 2026
RDU - SEA
Read more Delta reviews

Everything was good except wifi and a leaking drink chiller. The floor was all wet and my bag was soaked. Did not notice until debarking. Have not heard back from Delta. Even though this was leg one of an international flight in first class, they denied access to their Sky Club - very disappointing!

The staff was fine. The plane was extremely tight, and I paid for the wifi and it did not work at all. I was actually going to ask for a refund.

two hour delay and the Delta representative on the PA system was unable to understand

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

2+hrs delay without any reason provided and a cramped flight

We waited an hour on the runway to get a gate in Orlando

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

Flight was delayed due to crew being not on time

Flight crew issues delayed my flight by 2 1/2 hours. Causing me to miss my connection.

The staff on board and gate was nice - a welcome change from the usual. We also arrived early, which was a great benefit, given that it takes 30 minutes plus to get bags at SRQ.

We got delayed three hours and nobody thought to have the bathroom fixed while we were sitting waiting to board? took a full hour to have maintenance come and check it off. Had to shut the bathroom down twice so that the pilots could go to the bathroom. Everyone missed their connections.

Flight left on time and we arrived 25 minutes early! There was a gate available when we arrived so early on a busy Sunday afternoon! Flight attendants came around twice with the drinks cart.

Wonderful. Quick boarding. Early departure and we arrived 30 minutes early at our destination. Unfortunately, when you arrive early, there is still a departing aircraft at our gate. We had to park for 30 minutes until the gate was clear. So our early arrival was not really early at the gate. Otherwise it was a quick and smooth flight. Appreciated the efficiency.

Everything was great except for the boarding process. Everyone is lining up all at the same time and it’s hard to tell between the groups as they are way too large.

Women boarding passengers at the gate was absolutely rude and disrespectful of passengers. The flight attendant was absolutely delightful! Smiling and connected with the passengers. So happy. The seats are cramped and uncomfortable but I guess that’s just the way it is Communication regarding flight was excellent

Overall we had a good experience during our flight from San Francisco to Houston.

Airport terminal was outdated, flight was on a small jet with no wifi

We were delayed for about an hour from taking off due to traffic control procedures at the destination airport. But once in the air, the flight went well. The crew members were great and provided cabin service despite moderate turbulence during much of the flight.

it was a very short flight so my expectations were low.

As great a red-eye flight as red-eye flights can be.

Boarding is always an ordeal. Less dogs on flights. I am highly allergic to dogs and cats. Why are there so many animals these days?

I was on a small regional flight from Detroit to Philadelphia. When we landed the outside cruise needed to turn something off with the engine, which took quite a long time. Then, when they allowed us to get off the plane it was outside. They took their time, unloading all the luggage and waited till they unloaded all the luggage before they brought it over to us. It was 9 o’clock at night freezing cold out, and there was no proactive hustle to try to get people their luggage. It was really one of the worst experiences I think I’ve ever had with American until a manager came over. I don’t think they were going to even consider pulling the luggage over to the people that had been waiting outside for at least 10 minutes in the freezing cold.

Awful. Original flight was delayed 5 hours. Had to to take a connecting flight instead of direct. Had a 4 hour layover. I missed all of my morning meetings getting in 5 hours later than I was supposed to and had to change to take a later flight the next day to get them back in which cia time another $150.

I was trying to take 2 one and a half hour one way trips and I experienced almost 20 delays over the course of those two trips. Only a few of them were due to weather the rest was disorganization

The attendants were kind and helpful. A sugar-free drink would have been very welcome.

The entertainment options were at best, fair. It was exactly the same as my outbound flight. It would have been more entertaining if there were some series from Apple TV, HBO, Showtime or other carriers for me to catch up with.

The seat cushions were very worn so they were extremely uncomfortable.

Crew were all friendly and helpful. It was a short flight so just a beverage service with a cookie. After we were boarded the plane took about 45 minutes to leave the gate but it was New Year’s Eve so not shocking there was some delay. Overall good experience and very grateful.

Flight was on time is the only good thing. Person loading the plane called 1-6 to board at the same time, made it chaotic. Plane was too small for even putting backpacks in overhead. Seat for normal sized people were too small. The WIFI didn't work. When we landed had to wait because not enough ground crew.

the trip to madrid was uncomfortable with my legs touching the seat in front of me

Everything you need to know for your flight from Des Moines to Harrisburg

Information on your arrival and departure airports