MDT - DSM

$279 Find Cheap Flights from Harrisburg to Des Moines

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Harrisburg to Des Moines departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Harrisburg to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Harrisburg to Des Moines, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$309
Typical prices: $251-$346
American Airlines
Fri 4/17Sun 4/19
MDT - DSM • 1 stop
Cheapest one-way
$279
United Airlines
Tue 5/5
MDT - DSM • 1 stop
Top airlines
Cheapest • from $309 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Harrisburg and Des Moines. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $326 (round-trip)
Shortest trip • 4h 28m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 31% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Des Moines!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Harrisburg to Des Moines (MDT-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Harrisburg to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Harrisburg to Des Moines

Fri, Apr 17 - Sun, Apr 19
American Airlines Logo
5:38 am - 10:26 am
MDT
-
DSM
5h 48m
1 stop
American Airlines Logo
11:09 am - 6:01 pm
DSM
-
MDT
5h 52m
1 stop
$309American Airlines
Fri, Jun 12 - Sun, Jun 14
Allegiant Air Logo
11:33 am - 4:59 pm
MDT
-
DSM
6h 26m
1 stop
Allegiant Air Logo
4:01 pm - 4:50 pm
DSM
-
MDT
23h 49m
1 stop
$318Allegiant Air
Fri, Jun 12 - Sun, Jun 14
Allegiant Air Logo
11:33 am - 4:59 pm
MDT
-
DSM
6h 26m
1 stop
Allegiant Air Logo
4:01 pm - 4:50 pm
DSM
-
MDT
23h 49m
1 stop
$325Allegiant Air
Thu, Apr 9 - Mon, Apr 13
United Airlines Logo
5:52 pm - 9:32 pm
MDT
-
DSM
4h 40m
1 stop
United Airlines Logo
7:16 pm - 12:42 am
DSM
-
MDT
4h 26m
1 stop
$329United Airlines
Thu, Apr 9 - Mon, Apr 13
United Airlines Logo
5:52 pm - 9:32 pm
MDT
-
DSM
4h 40m
1 stop
United Airlines Logo
3:21 pm - 11:28 pm
DSM
-
MDT
7h 07m
2 stops
$334United Airlines
Wed, Apr 1 - Sun, Apr 5
United Airlines Logo
5:52 pm - 9:32 pm
MDT
-
DSM
4h 40m
1 stop
United Airlines Logo
3:21 pm - 9:18 pm
DSM
-
MDT
4h 57m
1 stop
$339United Airlines
Wed, Apr 1 - Sun, Apr 5
United Airlines Logo
6:15 am - 10:44 am
MDT
-
DSM
5h 29m
1 stop
United Airlines Logo
6:20 am - 1:55 pm
DSM
-
MDT
6h 35m
2 stops
$344United Airlines
Wed, Apr 1 - Sun, Apr 5
United Airlines Logo
6:15 am - 12:29 pm
MDT
-
DSM
7h 14m
2 stops
United Airlines Logo
6:20 am - 1:55 pm
DSM
-
MDT
6h 35m
2 stops
$349United Airlines
Sat, Jun 13 - Tue, Jun 23
United Airlines Logo
5:50 pm - 9:40 pm
MDT
-
DSM
4h 50m
1 stop
United Airlines Logo
11:23 am - 4:54 pm
DSM
-
MDT
4h 31m
1 stop
$383United Airlines
Fri, Jun 12 - Sun, Jun 14
Allegiant Air Logo
11:33 am - 4:59 pm
MDT
-
DSM
6h 26m
1 stop
Allegiant Air Logo
10:53 am - 9:23 am
DSM
-
MDT
21h 30m
2 stops
$397Allegiant Air
Booking Insights

KAYAK's insights & trends for Harrisburg to Des Moines flights

Get data-powered insights and trends into flights from Harrisburg to Des Moines to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Harrisburg to Des Moines?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Harrisburg to Des Moines departing in April.

What is the cheapest month to fly from Harrisburg to Des Moines?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Harrisburg to Des Moines, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Harrisburg to Des Moines is September, where tickets cost $278 (return) on average. On the other hand, the most expensive months are July and June, where the average cost of round-trip tickets is $620 and $586 respectively.

Good to know

Low seasonJanuary
Cheapest flight$279
Best time to beat the crowds with an average 17% drop in price.
Most popular time to fly and prices are also 11% lower on average.
Flight from Harrisburg to Des Moines

When to book flights from Harrisburg to Des Moines

Are your dates flexible? Find out the best times to travel from Harrisburg to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Harrisburg to Des Moines

  • What is the cheapest flight from Harrisburg to Des Moines?

    In the last 3 days, the lowest price for a flight from Harrisburg to Des Moines was $279 for a one-way ticket and $309 for a round-trip.

  • Do I need a passport to fly between Harrisburg and Des Moines?

    No

  • Which aircraft models fly most regularly from Harrisburg to Des Moines?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Harrisburg to Des Moines?

    oneworld, Star Alliance, and SkyTeam are the airline alliances operating flights between Harrisburg and Des Moines, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Harrisburg to Des Moines, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Harrisburg to Des Moines are Delta and United Airlines. With an average price for the route of $383 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $323 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Harrisburg to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Harrisburg to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Harrisburg to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from Harrisburg is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Harrisburg to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to Harrisburg with another airline. Booking your flights between Harrisburg and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Harrisburg to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from Harrisburg up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Harrisburg to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from Harrisburg to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Harrisburg to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8292 reviews
7.9Comfort
7.2Food
8.1Boarding
7.8Entertainment
8.5Crew
Airline reviews

I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.

4.0 OkayAnonymous, Mar 2026
CAE - ATL
Read more Delta reviews

I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.

NEVER MADE THE FLIGHT BECAUSE DELTA SAID THEY CAN NOT

THEY FAILED ME AND I NEVER GOT ON THE FLIGHT BECAUSE IT WAS SO DELAYED! I ENDED UP HAVING TO PAY OUT OF POCKET FOR A HOTEL AND STAY IN NASHVILLE TO CATCH A FLIGHT FOR THE FOLLOWING DAY. DELTA IS POOR CUSTOMER SERVICE>

8 hours late and the plane smelled like urine, that smell in the morning when your child wet the bed in the night.

My flight was canceled on Sunday. Rebooking took three hours. Had to pay for accommodations another night. New flight was delayed for 5 hours, all that was sent was a 12 dollar food voucher, which doesn’t tell you how to use it. Then when we landed we had to sit on the plane for an hour before we could get off.

Miserable. This entire round trip was miserable. I booked evening flights to and from Detroit on consecutive days that should have had me at my destination by 10:30. Instead I arrived after 3am on my flight to Detroit and after midnight on my return. Multiple unforced errors like awaiting bags to get put on the plane for almost an hour in Detroit and a 20 minute delay to pull up to the gate in Atlanta has me rethinking my assumption that delta is the best and most reliable airline

Perhaps when you’re sitting in 1st class and the crew closes the bathroom for the pilots, there could be a notification other than holding your hands up as a blockade when you get there and you’re told the restrooms are closed please turn around … especially at night when visibility is poor and you’re met by a flight attendants with their arms up

First class is comfortable. Enjoyed a movie and was able to relax compared to coach.

Loved flying First Class. Very comfortable. The seat was amazing. Enjoyed a movie and was able to relax so much better than in coach.

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

Economy plus was so cramped I could not use my laptop. It was beyond bad.

OK, we were delayed and had to de plane and reboard.

United is one airline which regardless of how many separate United tickets in existence, if one flight breaks down, the airline will take care of all the flights.

Both our flights were delayed. Almost didn’t get in the second flight. Staff was rude to the bone.

Both my flight where delayed Had 25min to make it to my transfer flight

Everything was on time and service on the flight was great!

Wifi Bluetooth features for watching in flight movie was horrible. Screen kept blacking out no connection of sound although it said connected. Other than that smooth trip .

The travel company that you have on your site did me so wrong. I don’t know how it happened, but they put my son‘s name on my plane ticket flying to Vietnam. Along with his birthday. They would not have let me fly from Fort Myers to Ho Chi Minh City. I don’t think that I can ever use your service again. I typed my information into the browser along with my passport number and four days before I’m leaving I have to quickly search another ticket to fly out here.

Seats are uncomfortable. This has been a trend in the industry for decades. Trying to fit more seats on each plane to increase profits at the expense of the passenger.

The flight was delayed so we were dead tired, and after that the turbulence was horrible. I was very scared.

It would have been nice if American tried to care.

Delayed initially because they couldn’t print the flight details. Poor instruction on delay. When I got on the plane the flight attendant argued with me about whether my carry on would fit (it did, although she didn’t acknowledge that). No greeting (other than arguing with me) getting on or off the plane.

Beverage service was not good. Also just one service in 5 hr 30 min flight. No ask fir water ir anything beside one time beverage service.

They are always late and seats was also not having working charger

Pilot navigated severe weather/snow storm with skill. Described his intentions clearly

This flight captain and crew were amazing, started ahead of time of departure and reached 30 mins before arrival time. Amazing!

Long delays, lack of information about the status of the flight. The flight was delayed 4 times.

Everything about the flight was lovely. My only suggestion would be to offer a few more options of tv series from Apple TV or HBO.

The boarding by groups is pointless. The first two groups worked fine, but almost Noone boarded in goups three thru five leaving the vast majority boarding when group six was called. It defeated the purpose of spreading out the crowd.

Delays to take off and to leave the plane after landing added a lot of time to this flight.

Everything you need to know for your flight from Harrisburg to Des Moines

Information on your arrival and departure airports