MDT - DSM

$319 Find Cheap Flights from Harrisburg to Des Moines - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$319
Typical prices: $308-$476
Delta
Mon 11/26Sat 12/15
MDT - DSM • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Harrisburg and Des Moines. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
October
Cheapest • 20% price drop
November
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Philadelphia (PHL)
Cheapest • Avg $390 (round-trip)
Detroit Metropolitan Wayne County (DTW)
Shortest trip • 4h 28m (one-way)
Insights
Insights
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Flight Deals

Cheap Flights from Harrisburg to Des Moines (MDT-DSM)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Harrisburg to Des Moines

Thu, Nov 26 - Tue, Dec 15
Delta Logo
6:00 am - 9:46 amMDT  Harrisburg-DSM Des Moines
4h 46m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:24 am - 11:40 amDSM  Des Moines-MDT Harrisburg
4h 16m1 stop Detroit Metropolitan Wayne County
$319Delta
Tue, Nov 24 - Tue, Dec 1
American Airlines Logo
7:55 pm - 12:19 amMDT  Harrisburg-DSM Des Moines
5h 24m1 stop Chicago O'Hare Intl
American Airlines Logo
7:07 am - 1:35 pmDSM  Des Moines-MDT Harrisburg
5h 28m1 stop Chicago O'Hare Intl
$339American Airlines
Thu, Nov 26 - Tue, Dec 15
United Airlines Logo
6:15 am - 2:24 pmMDT  Harrisburg-DSM Des Moines
9h 09m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
United Airlines Logo
11:27 am - 4:58 pmDSM  Des Moines-MDT Harrisburg
4h 31m1 stop Chicago O'Hare Intl
$344United Airlines
Sat, Sep 26 - Mon, Sep 28
United Airlines Logo
5:54 pm - 9:23 pmMDT  Harrisburg-DSM Des Moines
4h 29m1 stop Chicago O'Hare Intl
United Airlines Logo
3:11 pm - 9:50 pmDSM  Des Moines-MDT Harrisburg
5h 39m1 stop Chicago O'Hare Intl
$349United Airlines
Sat, Sep 26 - Mon, Sep 28
United Airlines Logo
2:55 pm - 9:23 pmMDT  Harrisburg-DSM Des Moines
7h 28m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
United Airlines Logo
3:11 pm - 9:50 pmDSM  Des Moines-MDT Harrisburg
5h 39m1 stop Chicago O'Hare Intl
$354United Airlines
Tue, Nov 24 - Tue, Dec 1
American Airlines Logo
7:55 pm - 12:19 amMDT  Harrisburg-DSM Des Moines
5h 24m1 stop Chicago O'Hare Intl
American Airlines Logo
1:58 pm - 11:03 pmDSM  Des Moines-MDT Harrisburg
8h 05m2 stops Chicago O'Hare Intl Boston Logan Intl
$378American Airlines
Fri, Sep 25 - Sat, Oct 3
United Airlines Logo
5:54 pm - 11:35 pmMDT  Harrisburg-DSM Des Moines
6h 41m1 stop Chicago O'Hare Intl
United Airlines Logo
8:00 am - 1:27 pmDSM  Des Moines-MDT Harrisburg
4h 27m1 stop Chicago O'Hare Intl
$399United Airlines
Fri, Oct 9 - Tue, Oct 13
American Airlines Logo
7:06 pm - 10:43 pmMDT  Harrisburg-DSM Des Moines
4h 37m1 stop Philadelphia
American Airlines Logo
7:29 am - 2:45 pmDSM  Des Moines-MDT Harrisburg
6h 16m1 stop Chicago O'Hare Intl
$408American Airlines
Mon, Oct 12 - Mon, Oct 19
American Airlines Logo
8:09 pm - 12:14 amMDT  Harrisburg-DSM Des Moines
5h 05m1 stop Chicago O'Hare Intl
American Airlines Logo
2:01 pm - 10:19 pmDSM  Des Moines-MDT Harrisburg
7h 18m1 stop Chicago O'Hare Intl
$418American Airlines
Sun, Oct 11 - Thu, Oct 15
Delta Logo
6:13 am - 9:42 amMDT  Harrisburg-DSM Des Moines
4h 29m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:00 am - 11:33 amDSM  Des Moines-MDT Harrisburg
4h 33m1 stop Detroit Metropolitan Wayne County
$967Delta
Booking Insights

Price, demand and travel trends for Harrisburg to Des Moines flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Harrisburg to Des Moines with more confidence.

How much is a round-trip flight from Harrisburg to Des Moines?

Round-trip flights from Harrisburg to Des Moines start at $319. Prices are typical for this route right now, with typical round-trip fares ranging from $308 to $476. The lowest price found in the past 5 days was $319 on Delta.

What's the cheapest day of the week to fly from Harrisburg to Des Moines?

Thursday is the cheapest day of the week to fly from Harrisburg to Des Moines, it is 13% cheaper than the average day. Monday is the most expensive day with flight prices 130% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Harrisburg to Des Moines?

  • October is the cheapest month to fly from Harrisburg to Des Moines at $283 round-trip.
  • April ($788) and June ($466) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 178% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Harrisburg to Des Moines flights

Low season

January
Best time to beat the crowds but there is an average 20% increase in price.
Most popular time to fly with an average 3% increase in price.

When to book flights from Harrisburg to Des Moines

Are your dates flexible? Find out the best times to travel from Harrisburg to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Harrisburg to Des Moines flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Harrisburg to Des Moines?

    Flights from Harrisburg to Des Moines usually depart from Harrisburg (MDT) and arrive at Des Moines (DSM).

  • What cabin classes can I book on flights from Harrisburg to Des Moines?

    Only Economy Class is available on flights from Harrisburg to Des Moines.

  • Which airports do connecting flights from Harrisburg to Des Moines pass through?

    One-stop flights from Harrisburg to Des Moines most commonly connect through:

    • Chicago O'Hare Intl (ORD) - 68% of one-stop connections
    • Detroit Metropolitan Wayne County (DTW) - 26% of one-stop connections
    • Philadelphia (PHL) - 4% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 1% of one-stop connections

    Chicago O'Hare Intl (ORD) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Harrisburg to Des Moines?

    Yes. Being flexible with your travel dates can save you up to 63% on the Harrisburg to Des Moines route. Thursday is the cheapest departure day at $308 round-trip on average, while Monday is the most expensive at $815, a difference of $507. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in Des Moines?

    Some of the most popular sights in Des Moines are Iowa Events Center, UnityPoint Health - Des Moines and Des Moines Civic Center. These are among the most viewed places in Des Moines on KAYAK.

  • How long is a flight from Harrisburg to Des Moines?

    A nonstop flight from Harrisburg to Des Moines takes 0h 00m, covering 886 miles.

  • Do I need a passport to fly from Harrisburg to Des Moines?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Harrisburg to Des Moines changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $319 to $1,406. That means the highest observed fare was about 4x higher than the lowest one.

  • How much time can I save by choosing a different layover airport from Harrisburg to Des Moines?

    Flying via Detroit Metropolitan Wayne County (DTW) gives the shortest average 1-stop total travel time at 4h 28m, compared with 5h 12m via Chicago O'Hare Intl (ORD) and 5h 19m via Atlanta Hartsfield-Jackson (ATL).

  • What is the time difference between Harrisburg and Des Moines?

    Des Moines is 1 hour behind Harrisburg (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Des Moines Airport (DSM)?

    Des Moines Airport (DSM) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:
    • Hertz
    • Payless
    • Budget
    • Alamo
    • Avis

  • How much should I expect to pay for a Harrisburg to Des Moines flight?

    Round-trip flights from Harrisburg to Des Moines range from $308 to $476, with an average of $353 over the past 12 months. Anything below $308 counts as a good deal.

Your guide to booking Harrisburg to Des Moines flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Thursday departure instead of Monday. On this route, Thursday flights average $308 - about $507 less than Monday (62% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Harrisburg to Des Moines trip for October. Fares historically average $283 round-trip in that month - typically $505 less than the most expensive month, which is April (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Des Moines Airport.
    - Days Inn & Suites by Wyndham Des Moines Airport
    - Holiday Inn Des Moines-Airport/Conf Center By IHG
    - Quality Inn & Suites Des Moines Airport

More options for your flight from Harrisburg to Des Moines

Complete your trip to Des Moines with a hotel stay or car rental

Car rentals in Des Moines
Hotels in Des Moines
Vacations in Des Moines