Find Cheap Flights from Des Moines to Key West (DSM - EYW)

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
The price shown for each flight will be the average for all passengers including any infants.
Compare vs. KAYAK all | none
Browse Origins:
Browse Destinations:

Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights from Des Moines to Key West

(Round-trip)
Depart: Tue Aug 22 2017 Return: Tue Aug 29 2017 Trip spans 8 days
United
United
DSM
1:15a
EYW
9:10a
7h 55m
2 stops
EYW
9:05a
DSM
8:44p
11h 39m
2 stops
Depart: Tue Aug 1 2017 Return: Tue Aug 8 2017 Trip spans 8 days
Major Airline
Major Airline
DSM
2:00a
EYW
3:42a
1h 42m
2 stops
EYW
2:00a
DSM
5:42a
3h 42m
2 stops
Depart: Sun Oct 1 2017 Return: Wed Oct 11 2017 Trip spans 11 days
American Airlines
American Airlines
DSM
1:15p
EYW
7:52a
18h 37m
2 stops
EYW
3:00a
DSM
10:07a
7h 07m
2 stops
Depart: Mon Jul 3 2017 Return: Mon Jul 10 2017 Trip spans 8 days
Delta
Delta
DSM
7:29a
EYW
12:09p
4h 40m
1 stop
EYW
3:00a
DSM
7:54a
4h 54m
1 stop
Depart: Tue Oct 3 2017 Return: Thu Oct 5 2017 Trip spans 3 days
United
United
DSM
4:09a
EYW
12:23p
8h 14m
2 stops
EYW
4:40a
DSM
6:19p
13h 39m
2 stops
Depart: Wed Oct 4 2017 Return: Thu Oct 5 2017 Trip spans 2 days
United
United
DSM
4:09a
EYW
4:18p
12h 09m
2 stops
EYW
9:05a
DSM
6:19p
9h 14m
2 stops
Depart: Sat Sep 30 2017 Return: Wed Oct 11 2017 Trip spans 12 days
American Airlines
American Airlines
DSM
9:37a
EYW
5:47p
8h 10m
2 stops
EYW
3:00a
DSM
10:07a
7h 07m
2 stops
Depart: Thu Jun 15 2017 Return: Tue Jun 20 2017 Trip spans 6 days
Major Airline
Major Airline
DSM
2:00a
EYW
3:42a
1h 42m
2 stops
EYW
2:00a
DSM
5:42a
3h 42m
2 stops
Depart: Wed Jul 5 2017 Return: Mon Jul 10 2017 Trip spans 6 days
Delta
Delta
DSM
7:32a
EYW
2:43p
7h 11m
1 stop
EYW
3:00a
DSM
7:54a
4h 54m
1 stop
Depart: Mon Oct 2 2017 Return: Thu Oct 5 2017 Trip spans 4 days
United
United
DSM
4:09a
EYW
4:18p
12h 09m
2 stops
EYW
4:40a
DSM
6:19p
13h 39m
2 stops
Depart: Sun Jun 11 2017 Return: Wed Jun 14 2017 Trip spans 4 days
American Airlines
American Airlines
DSM
2:12a
EYW
5:47p
15h 35m
2 stops
EYW
3:15p
DSM
5:39a
14h 24m
2 stops
Depart: Fri Sep 29 2017 Return: Thu Oct 5 2017 Trip spans 7 days
United
United
DSM
11:05a
EYW
6:48a
19h 43m
2 stops
EYW
4:40a
DSM
6:19p
13h 39m
2 stops
Depart: Thu Oct 5 2017 Return: Wed Oct 11 2017 Trip spans 7 days
American Airlines
American Airlines
DSM
1:50a
EYW
5:47p
15h 57m
2 stops
EYW
3:00a
DSM
10:07a
7h 07m
2 stops
Depart: Fri Jul 14 2017 Return: Mon Jul 17 2017 Trip spans 4 days
Delta
Delta
DSM
7:29a
EYW
2:43p
7h 14m
1 stop
EYW
1:54p
DSM
7:45p
5h 51m
1 stop
Depart: Thu Jul 20 2017 Return: Mon Jul 24 2017 Trip spans 5 days
Major Airline
Major Airline
DSM
2:00a
EYW
3:42a
1h 42m
2 stops
EYW
2:00a
DSM
5:42a
3h 42m
2 stops
Depart: Sat Jul 15 2017 Return: Thu Jul 20 2017 Trip spans 6 days
American Airlines
American Airlines
DSM
2:00a
EYW
5:47p
15h 47m
2 stops
EYW
3:15p
DSM
5:39a
14h 24m
2 stops
Depart: Fri Jun 16 2017 Return: Sat Jun 24 2017 Trip spans 9 days
American Airlines
American Airlines
DSM
2:14a
EYW
5:47p
15h 33m
2 stops
EYW
3:15p
DSM
5:39a
14h 24m
2 stops
Depart: Sun Nov 5 2017 Return: Mon Nov 13 2017 Trip spans 9 days
Major Airline
Major Airline
DSM
1:00a
EYW
2:42a
1h 42m
2 stops
EYW
12:00a
DSM
3:42a
3h 42m
2 stops
Depart: Thu Jul 27 2017 Return: Sun Jul 30 2017 Trip spans 4 days
United
United
DSM
3:50a
EYW
1:44p
9h 54m
2 stops
EYW
6:42a
DSM
7:23p
12h 41m
2 stops
Depart: Sat Jul 1 2017 Return: Fri Jul 7 2017 Trip spans 7 days
American Airlines
American Airlines
DSM
5:30a
EYW
5:47p
12h 17m
2 stops
EYW
3:15p
DSM
5:39a
14h 24m
2 stops
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

We attempt to get accurate prices, however, prices are not guaranteed.

Here's why:

We’re not the seller.
At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

We compile tonnes of data for you
Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

If you have more questions or if you have a bad price to report to us,
please send us an email and someone from our team will get back to you promptly.

Airports
Origin

Des Moines
$366
Destination

Key West
$366