DSM - LEX

$319 Find Cheap Flights from Des Moines to Lexington - Compare and Save

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Lexington departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$319
Typical prices: $308-$517
American Airlines
Thu 9/10Sun 9/13
DSM - LEX • 1 stop
Cheapest one-way
$369
United Airlines
Sun 8/23
DSM - LEX • 1 stop
Top airlines
Cheapest • from $319 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
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Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Lexington. You'll need at least 1 connection.
Insights
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Insights
Top layover airports
Cheapest • Avg $308 (round-trip)
Shortest trip • 4h 06m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 100% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to Lexington!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Lexington (DSM-LEX)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Lexington that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Lexington

Thu, Sep 10 - Sun, Sep 13
American Airlines Logo
5:56 pm - 11:46 pm
DSM
-
LEX
4h 50m
1 stop
American Airlines Logo
5:00 am - 10:19 am
LEX
-
DSM
6h 19m
1 stop
$319American Airlines
Thu, Sep 3 - Tue, Sep 8
American Airlines Logo
1:08 pm - 6:43 pm
DSM
-
LEX
4h 35m
1 stop
American Airlines Logo
6:59 pm - 12:20 am
LEX
-
DSM
6h 21m
1 stop
$339American Airlines
Sun, Sep 13 - Sun, Sep 20
American Airlines Logo
5:57 pm - 11:46 pm
DSM
-
LEX
4h 49m
1 stop
American Airlines Logo
5:00 am - 10:19 am
LEX
-
DSM
6h 19m
1 stop
$339American Airlines
Sat, Aug 29 - Mon, Aug 31
American Airlines Logo
1:08 pm - 6:43 pm
DSM
-
LEX
4h 35m
1 stop
American Airlines Logo
6:34 am - 10:00 am
LEX
-
DSM
4h 26m
1 stop
$339American Airlines
Fri, Aug 14 - Tue, Aug 18
United Airlines Logo
1:21 pm - 8:28 pm
DSM
-
LEX
6h 07m
1 stop
United Airlines Logo
7:00 am - 10:26 am
LEX
-
DSM
4h 26m
1 stop
$349United Airlines
Thu, Dec 31 - Sun, Jan 3
United Airlines Logo
8:00 am - 1:13 pm
DSM
-
LEX
4h 13m
1 stop
United Airlines Logo
5:50 pm - 9:21 pm
LEX
-
DSM
4h 31m
1 stop
$498United Airlines
Thu, Dec 31 - Sun, Jan 3
United Airlines Logo
8:00 am - 1:13 pm
DSM
-
LEX
4h 13m
1 stop
United Airlines Logo
5:50 pm - 9:21 pm
LEX
-
DSM
4h 31m
1 stop
$508United Airlines
Sun, Sep 13 - Sun, Sep 20
Delta Logo
5:45 am - 11:45 am
DSM
-
LEX
5h 00m
1 stop
Delta Logo
5:57 pm - 10:26 pm
LEX
-
DSM
5h 29m
1 stop
$509Delta
Sun, Sep 13 - Sun, Sep 20
Delta Logo
10:59 am - 9:16 pm
DSM
-
LEX
9h 17m
2 stops
Delta Logo
5:57 pm - 10:26 pm
LEX
-
DSM
5h 29m
1 stop
$1,216Delta
Sun, Sep 13 - Sun, Sep 20
Delta Logo
10:59 am - 9:16 pm
DSM
-
LEX
9h 17m
2 stops
Delta Logo
10:39 am - 4:48 pm
LEX
-
DSM
7h 09m
2 stops
$1,903Delta
Booking Insights

KAYAK's insights & trends for Des Moines to Lexington flights

Get data-powered insights and trends into flights from Des Moines to Lexington to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Des Moines to Lexington?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Lexington, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Lexington is January, where tickets cost $0 (return) on average. On the other hand, the most expensive months are October and February, where the average cost of round-trip tickets is $850 and $793 respectively.

Good to know

Low season

September

Cheapest flight

$319
Best time to beat the crowds with an average 44% drop in price.
Most popular time to fly and prices are also 44% lower on average.
Flight from Des Moines to Lexington

When to book flights from Des Moines to Lexington

Are your dates flexible? Find out the best times to travel from Des Moines to Lexington based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Lexington

  • What is the cheapest flight from Des Moines to Lexington?

    In the last 5 days, the lowest price for a flight from Des Moines to Lexington was $369 for a one-way ticket and $319 for a round-trip.

  • Do I need a passport to fly between Des Moines and Lexington?

    No

  • Which airports will I be using when flying from Des Moines to Lexington?

    On your way to Lexington, you’ll fly out from Des Moines. You’ll be landing at Lexington Blue Grass.

  • Which aircraft models fly most regularly from Des Moines to Lexington?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Lexington?

    oneworld, and Star Alliance are the airline alliances operating flights between Des Moines and Lexington, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Lexington, United Airlines or American Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Lexington are United Airlines and American Airlines. With an average price for the route of $550 and an overall rating of 7.4, United Airlines is the most popular choice. American Airlines is also a great choice for the route, with an average price of $511 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Des Moines to Lexington?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Lexington.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Lexington?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Lexington from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Lexington?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Lexington with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and LEX can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Lexington?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Lexington from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Lexington

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Lexington. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Lexington? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 10058 reviews
7.1Entertainment
6.7Food
7.7Boarding
7.3Comfort
8.1Crew
Airline reviews

Flight staff and all was fine. Food always sucks on planes so nothing new.

10.0 ExcellentJames, Aug 2026
RNO - IAH
Read more United Airlines reviews

Flight staff and all was fine. Food always sucks on planes so nothing new.

The flight crew were very helpful. The seats were very close together. There was barely room to sit without touching the person next to you.

I’m an EP on AA every year for more than a decade but this was a very pleasant and surprising experience. Clean and sizable plane for HOU to CHI. 5 row first class. And excellent food in first class the steak option was really good. Your flight attendants even better. Seat 5A

It was hot and not as comfortable as the flight to Chicago. Must have been a different plane that needs to be worked on or replaced.

1 flight cancelled Had to fly out of different city Flight at new departure city was delayed 3 hours causing us to miss connecting flights. By the time we did make it to Prague our luggage did not. Had to wait day and a half for luggage to be delivered. Customer service was not good. Agents did not arrive at gate until 5-10 minutes before boarding

It was better than excellent. The staff in Mason City were great. The young woman that pushed my wheelchair did more than could be expected of her. She came from India 17 years ago. I don't remember her name.

Short flight, but no drink/snack service. The flights both going and coming were delayed.

Very rough getting into denver. my kid threw up it was so rough.

Liked that we left on time for each flight. Snacks not the best, but we're okay.

I had requested wheelchair assistance prior to flight. The airport staff had no record of it. It was not provided at Cedar Rapids which was a small airport, so I managed on my own. At O'Hare airport the same thing happened. The staff told me they had no record of my request for a wheel chair. But they finally provided it after a delay when I insisted that I needed it.

The gate got changed several times and the flight was delayed over an hour. Awful experience

The boarding process needs to be fixed. The zone don't work, especially when there is hardly anyone in zones 3, 4,and 5, leaving the majority of the passengers backed up in the aisle, especially because passengers seated near the front are blocking passengers who are seated in the rear of the plane. It would also help if the size of carry on bags was more strictly enforced.

My Internet did not work for Outlook email or basically anything. I paid for one hour of in-flight usage and it was terrible. I spent a lot of time on different sites and browsers with no luck and a lot of frustration. Other than that, the flight was on time, crew was nice, service was fine. Seat was OK even though I paid for the extra 6 inches. I cannot imagine how tight the seats in the back must be.

In flight connectivity (via T-Mobile) was often not working.

Terrible. Internet/kiosk glitch prevented baggage checkin. Line at ticket co in Ter was under serviced and did not move. Agents did not call for flight but rather allowed time to pass. Then told each person as they reached the front if line that it was too late to check bags so they’d have to rebook flights. At least 15 people missed the flight as a result of this incompetence.

It was exactly what I expected, actually arriving sooner than scheduled.

I was not given the option to get on a different flight even though I was going to miss my connection due to weather delays (I did). When I called early in the morning, they said it wasn't delayed long enough; though I knew it would be by the time it was time for the flight ... it was and by that time it was too late. I wasn't given the option to pre-board with my toddler, and the food service was less than normal due to delays .... at least that's what the crew said.

American is a steady for me. I always get what I expect from them. Sincere effort to get me from one place to another.

Terrible, they canceled my flight due to an issue they had, couldn't fly me into the same place within 24 hrs so had to fly in 2.5 hrs away from my destination and spend even more money. The customer service was terrible (except at the airport in Charleston). Had to call to get my checked baggage fees reimbursed 2 wks later in which one customer service agent was very rude, wouldn't listen and then hung up on me. The second lady I spoke with was actually able to help me with that part thankfully. Would not recommend flying AA.

Sat on the tarmac for a good half hour before take off

Everything you need to know for your flight from Des Moines to Lexington

Information on your arrival and departure airports