DSM - MHT

$301 Find Cheap Flights from Des Moines to Manchester - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Manchester departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$362
American Airlines
Tue 9/1Mon 9/7
DSM - MHT • 1 stop
Cheapest one-way
$301
United Airlines
Fri 9/25
DSM - MHT • 2 stops
Top airlines
Cheapest • from $362 (round-trip)
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
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Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Manchester. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $344 (round-trip)
Shortest trip • 4h 31m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 100% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to Manchester!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Manchester (DSM-MHT)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Manchester that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Manchester

Tue, Sep 1 - Mon, Sep 7
American Airlines Logo
5:46 am - 11:39 am
DSM
-
MHT
4h 53m
1 stop
American Airlines Logo
5:41 pm - 12:20 am
MHT
-
DSM
7h 39m
1 stop
$362American Airlines
Tue, Sep 1 - Mon, Sep 7
American Airlines Logo
6:55 am - 4:38 pm
DSM
-
MHT
8h 43m
2 stops
American Airlines Logo
5:41 pm - 12:20 am
MHT
-
DSM
7h 39m
1 stop
$367American Airlines
Wed, Sep 30 - Sat, Oct 3
American Airlines Logo
5:56 pm - 12:31 am
DSM
-
MHT
5h 35m
1 stop
American Airlines Logo
7:03 am - 1:59 pm
MHT
-
DSM
7h 56m
1 stop
$385American Airlines
Thu, Sep 17 - Wed, Sep 23
American Airlines Logo
5:56 pm - 12:15 am
DSM
-
MHT
5h 19m
1 stop
American Airlines Logo
5:59 pm - 12:04 am
MHT
-
DSM
7h 05m
1 stop
$385American Airlines
Sat, Oct 3 - Tue, Oct 6
Southwest Logo
5:50 am - 4:05 pm
DSM
-
MHT
9h 15m
2 stops
Southwest Logo
1:50 pm - 9:55 pm
MHT
-
DSM
9h 05m
2 stops
$395Southwest
Tue, Sep 1 - Mon, Sep 7
Southwest Logo
6:10 am - 5:35 pm
DSM
-
MHT
10h 25m
2 stops
Southwest Logo
5:40 am - 1:45 pm
MHT
-
DSM
9h 05m
2 stops
$438Southwest
Wed, Oct 28 - Sat, Oct 31
United Airlines Logo
9:00 am - 11:59 pm
DSM
-
MHT
13h 59m
2 stops
United Airlines Logo
9:25 am - 7:16 pm
MHT
-
DSM
10h 51m
2 stops
$439United Airlines
Fri, Sep 25 - Sun, Sep 27
Multiple Airlines Logo
3:04 pm - 9:15 am
DSM
-
MHT
17h 11m
1 stop
Multiple Airlines Logo
12:24 pm - 5:09 pm
MHT
-
DSM
29h 45m
2 stops
$454Multiple Airlines
Thu, Sep 17 - Wed, Sep 23
Southwest Logo
5:40 am - 2:55 pm
DSM
-
MHT
8h 15m
2 stops
Southwest Logo
5:35 am - 11:50 am
MHT
-
DSM
7h 15m
2 stops
$471Southwest
Tue, Nov 17 - Wed, Nov 18
United Airlines Logo
3:15 pm - 11:59 pm
DSM
-
MHT
7h 44m
2 stops
United Airlines Logo
9:25 am - 8:36 pm
MHT
-
DSM
12h 11m
2 stops
$485United Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Manchester flights

Get data-powered insights and trends into flights from Des Moines to Manchester to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Des Moines to Manchester?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Manchester, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Manchester is November, where tickets cost $0 (return) on average. On the other hand, the most expensive months are July and May, where the average cost of round-trip tickets is $579 and $491 respectively.

Good to know

Cheapest flight

$301
Most popular time to fly and prices are also 16% lower on average.
Flight from Des Moines to Manchester

When to book flights from Des Moines to Manchester

Are your dates flexible? Find out the best times to travel from Des Moines to Manchester based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Manchester

  • What is the cheapest flight from Des Moines to Manchester?

    In the last 5 days, the lowest price for a flight from Des Moines to Manchester was $301 for a one-way ticket and $362 for a round-trip.

  • Do I need a passport to fly between Des Moines and Manchester?

    A passport is not required to fly from Des Moines to Manchester.

  • Which airports will I be using when flying from Des Moines to Manchester?

    Des Moines and Manchester are both served by 1 main airport. You will leave Des Moines from Des Moines and will be arriving at Manchester.

  • Which aircraft models fly most regularly from Des Moines to Manchester?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Manchester?

    oneworld is the only airline alliance operating flights between Des Moines and Manchester.

  • Which is the best airline for flights from Des Moines to Manchester, Southwest or American Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Manchester are Southwest and American Airlines. With an average price for the route of $486 and an overall rating of 8.0, Southwest is the most popular choice. American Airlines is also a great choice for the route, with an average price of $381 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Des Moines to Manchester?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Manchester.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Manchester?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Manchester from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Manchester?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Manchester with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and MHT can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Manchester?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Manchester from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Manchester

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Manchester. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Manchester? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4224 reviews
8.6Crew
8.1Boarding
8.0Comfort
7.5Entertainment
7.0Food
Airline reviews

The flight was delayed due to earlier issues at other airports. The crew was excellent & made it a good trip.

6.0 GoodJeremy, Aug 2026
STL - PHL
Read more Southwest reviews

The flight was delayed due to earlier issues at other airports. The crew was excellent & made it a good trip.

Boarding process of asking for volunteers to check bags goes against the system you had before with 2 bags checked free. This process is more of a guilt trip than a caring attitude toward the customer. In addition bag-size scrutiny has increased which also slows down the process of boarding. My wife said she will not fly on your airline again unless there is no other option.

Eveeyrime I fly they are begging for bags due to cabin overhead space. What they should so ia take the bags that are clearly too big to fit wheels first on their side. And those of us who give up the bag should really get their bags first. When boarding, nobody wants stupid jokes about how hot it is on board. Give us some cool air. Im usually sick from the heat by the time we take off.

No wifi, seems to be very common with Southwest currently. Everything else was normal.

Poor customer service, no accommodation for passengers when the flight was delayed over 5 hours.

Friendly crew kept coming by to make sure all was ok, provide additional refreshments, etc.

It was good. Last flight was delayed but I always say that is in God's plan

Overall good, just screaming kids in the area the whole flight.

The crew canceled the complementary snack and drink in anticipation of turbulence that never materialized. I was counting on the drink (water) to take the the doses of medication - prescribed for my heart condition - that were due during the flight. Since no snack or meal was served on this flight, I cannot rate the food quality. Otherwise, this flight was excellent.

Really full flight, checked in ASAP and still mid Cs.

The flight was delayed 4 hours, and when we finally boarded, they told us that the fuel was only just then checked. So, we waited even longer to take off.

Great. Clean. Seats comfortable. Food was free. Had new release movies.

The airplane I love and I love I came back safe thank you American airlines

The plane was experiencing problems with the HVAC system, it was very cold in the front of the plane and very hot in the back.

The boarding process needs to be fixed. The zone don't work, especially when there is hardly anyone in zones 3, 4,and 5, leaving the majority of the passengers backed up in the aisle, especially because passengers seated near the front are blocking passengers who are seated in the rear of the plane. It would also help if the size of carry on bags was more strictly enforced.

In flight connectivity (via T-Mobile) was often not working.

Terrible. Internet/kiosk glitch prevented baggage checkin. Line at ticket co in Ter was under serviced and did not move. Agents did not call for flight but rather allowed time to pass. Then told each person as they reached the front if line that it was too late to check bags so they’d have to rebook flights. At least 15 people missed the flight as a result of this incompetence.

It was exactly what I expected, actually arriving sooner than scheduled.

Terrible, they canceled my flight due to an issue they had, couldn't fly me into the same place within 24 hrs so had to fly in 2.5 hrs away from my destination and spend even more money. The customer service was terrible (except at the airport in Charleston). Had to call to get my checked baggage fees reimbursed 2 wks later in which one customer service agent was very rude, wouldn't listen and then hung up on me. The second lady I spoke with was actually able to help me with that part thankfully. Would not recommend flying AA.

Delayed, missed connecting flight, ground crew double charged for international charges, were super rude and told me to just”deal with it” when I complained. Horrible airline, very frustrating.

Everything you need to know for your flight from Des Moines to Manchester

Information on your arrival and departure airports