$193 Find Cheap Flights from Des Moines to Mexico City Federal District - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Mexico City Federal District departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Book Cheap Des Moines to Mexico City Federal District Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Mexico City Federal District that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Mexico City Federal District

Fri, Sep 11 - Fri, Sep 18
Multiple Airlines Logo
8:30 pm - 5:30 pm
DSM
-
MEX
22h 00m
1 stop
Multiple Airlines Logo
11:05 am - 8:39 am
MEX
-
DSM
44h 34m
2 stops
$479Multiple Airlines
Mon, Sep 14 - Mon, Sep 21
Multiple Airlines Logo
8:30 pm - 5:30 pm
DSM
-
MEX
22h 00m
1 stop
Multiple Airlines Logo
8:40 am - 7:33 pm
MEX
-
DSM
9h 53m
1 stop
$481Multiple Airlines
Wed, Nov 4 - Tue, Nov 10
Multiple Airlines Logo
2:45 pm - 9:10 pm
DSM
-
MEX
30h 25m
1 stop
Multiple Airlines Logo
11:00 am - 1:55 pm
MEX
-
DSM
26h 55m
1 stop
$482Multiple Airlines
Mon, Aug 17 - Sun, Aug 23
Multiple Airlines Logo
10:06 pm - 8:00 pm
DSM
-
MEX
22h 54m
2 stops
Multiple Airlines Logo
8:40 am - 1:34 pm
MEX
-
DSM
27h 54m
1 stop
$484Multiple Airlines
Thu, Sep 10 - Thu, Sep 17
American Airlines Logo
6:57 pm - 2:00 pm
DSM
-
MEX
20h 03m
1 stop
American Airlines Logo
7:00 am - 6:58 pm
MEX
-
DSM
10h 58m
1 stop
$581American Airlines
Wed, Sep 16 - Wed, Sep 23
American Airlines Logo
5:56 pm - 12:07 pm
DSM
-
MEX
19h 11m
1 stop
American Airlines Logo
7:00 am - 11:12 pm
MEX
-
DSM
15h 12m
1 stop
$583American Airlines
Fri, Sep 11 - Fri, Sep 18
American Airlines Logo
9:51 am - 6:35 pm
DSM
-
MEX
9h 44m
1 stop
American Airlines Logo
3:31 pm - 11:59 pm
MEX
-
DSM
7h 28m
1 stop
$628American Airlines
Sat, Sep 5 - Tue, Sep 8
United Airlines Logo
3:02 pm - 11:10 pm
DSM
-
MEX
9h 08m
1 stop
United Airlines Logo
8:05 am - 4:19 pm
MEX
-
DSM
7h 14m
1 stop
$656United Airlines
Sun, Sep 13 - Sun, Sep 20
United Airlines Logo
6:15 am - 10:45 am
DSM
-
MEX
5h 30m
1 stop
United Airlines Logo
8:05 am - 4:19 pm
MEX
-
DSM
7h 14m
1 stop
$675United Airlines
Sun, Sep 13 - Sun, Sep 20
United Airlines Logo
11:33 am - 9:10 pm
DSM
-
MEX
10h 37m
1 stop
United Airlines Logo
8:05 am - 4:19 pm
MEX
-
DSM
7h 14m
1 stop
$676United Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Mexico City Federal District flights

Get data-powered insights and trends into flights from Des Moines to Mexico City Federal District to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Des Moines to Mexico City Federal District?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to Mexico City Federal District departing in September.

Flight prices are below average for this route right now.

Flights to Mexico City Federal District from Des Moines usually cost between $621 and $687 in September.
The lowest price found in the past 5 days was $479 on Multiple Airlines (Sep 11-Sep 18).

What is the cheapest month to fly from Des Moines to Mexico City Federal District?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Mexico City Federal District, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Mexico City Federal District is March, when tickets cost $549 (return) on average. On the other hand, the most expensive months are December and September, when the average cost of round-trip tickets is $1,019 and $802 respectively.

Good to know

Low season

March

Cheapest flight

$193
Best time to beat the crowds with an average 23% drop in price.
Most popular time to fly with an average 44% increase in price.
Flight from Des Moines to Mexico City

FAQs - booking Mexico City Federal District flights

  • How does KAYAK find such low prices on flights from Des Moines to Mexico City Federal District?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Mexico City Federal District.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Mexico City Federal District?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to Mexico City Federal District is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Mexico City Federal District?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to Mexico City Federal District with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Mexico City Federal District?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to Mexico City Federal District up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Mexico City Federal District

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Mexico City Federal District. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Mexico City Federal District? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 10061 reviews
7.3Comfort
8.1Crew
6.6Food
7.1Entertainment
7.7Boarding
Airline reviews

1 flight cancelled Had to fly out of different city Flight at new departure city was delayed 3 hours causing us to miss connecting flights. By the time we did make it to Prague our luggage did not. Had to wait day and a half for luggage to be delivered. Customer service was not good. Agents did not arrive at gate until 5-10 minutes before boarding

2.0 MediocreRuss, Jun 2026
FOD - ORD
Read more United Airlines reviews

1 flight cancelled Had to fly out of different city Flight at new departure city was delayed 3 hours causing us to miss connecting flights. By the time we did make it to Prague our luggage did not. Had to wait day and a half for luggage to be delivered. Customer service was not good. Agents did not arrive at gate until 5-10 minutes before boarding

I needed internet for critical matters and it never worked.

It was better than excellent. The staff in Mason City were great. The young woman that pushed my wheelchair did more than could be expected of her. She came from India 17 years ago. I don't remember her name.

Seats had less pitch than a regional jet. Food was OK. Have to buy alcohol on US based carriers flying international. Boarding was a mess. Did not have bags but overhead space was gone quick. Would like to see the airlines enforce the one bag over and one bag under policy

We had to deboard 2 times due to maintenance issues. They changed the plane, and then we got deviated to LAX due to maibtenance issues on the other plane, had to sleep at LAX and los a full day.

Very rough getting into denver. my kid threw up it was so rough.

Liked that we left on time for each flight. Snacks not the best, but we're okay.

Terrible! After boarding we were stuck on the plane for 3 hours with no air circulation during a heat wave.

All planes flying to Mexico City are very old. Seats don’t even have power outlets.

I bought internet for the flight. Don’t waste your money. I wasn’t able to download a 1 Mb file from Google Docs during a 3-4 hr period. You can only use WhatsApp and email if you are willing to wait.

The flight was very smooth and the meal in business class was great.

In flight connectivity (via T-Mobile) was often not working.

Terrible. Internet/kiosk glitch prevented baggage checkin. Line at ticket co in Ter was under serviced and did not move. Agents did not call for flight but rather allowed time to pass. Then told each person as they reached the front if line that it was too late to check bags so they’d have to rebook flights. At least 15 people missed the flight as a result of this incompetence.

It was exactly what I expected, actually arriving sooner than scheduled.

Terrible, they canceled my flight due to an issue they had, couldn't fly me into the same place within 24 hrs so had to fly in 2.5 hrs away from my destination and spend even more money. The customer service was terrible (except at the airport in Charleston). Had to call to get my checked baggage fees reimbursed 2 wks later in which one customer service agent was very rude, wouldn't listen and then hung up on me. The second lady I spoke with was actually able to help me with that part thankfully. Would not recommend flying AA.

Delayed multiple times. Boarding was ok but getting off the aircraft was a mess. So disorganized with staff trying to help the elderly but completely blocking path for anyone else to move. Bathroom was disgusting, probably caused by one of the customers but staff couldn't care less to help clean it. No one wanted to use it since the floor was completely soaked so everyone just lined up the other restroom while the staff just chit chat with each other while looking at us.

I think the seats on some of their planes are uncomfortable. You can be ok on a short flight of two hours but no more than that. The delays, and also the refreshments on the plane were not enough.

Terrible, oxygen masks were deployed mid-flight. We returned to airport. Took additional 12 hours to get home.

Lack of information. No meal for a 6hr international flight that departs during dinner time

The announcements for loading at the gate for my flight from Phoenix to Mex City was all in Spanish. The English only speaking flyers had no idea the plane was loading.

Everything you need to know for your flight from Des Moines to Mexico City Federal District

Information on your arrival and departure airports