$187 Find Cheap Flights from Des Moines to Mexico

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Mexico departing on 7/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Cheap Flights from Des Moines to Mexico

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Cancún
Cancún1 stop$393
Mexico City
Mexico City1 stop$459
Guadalajara
Guadalajara1 stop$459
Puerto Vallarta
Puerto Vallarta1 stop$593
León
León1 stop$565
Monterrey
Monterrey1 stop$443
Tijuana
Tijuana2 stops$373
Morelia
Morelia1 stop$569
Mérida
Mérida2 stops$708
Veracruz
Veracruz1 stop$601
Cancún
Cancún1 stop$393
Mexico City
Mexico City1 stop$459
Guadalajara
Guadalajara1 stop$459
Puerto Vallarta
Puerto Vallarta1 stop$593
León
León1 stop$565
Monterrey
Monterrey1 stop$443
Tijuana
Tijuana2 stops$373
Morelia
Morelia1 stop$569
Mérida
Mérida2 stops$708
Veracruz
Veracruz1 stop$601

Book Cheap Des Moines to Mexico Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Mexico that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Mexico

jeu., mai 28 - jeu., juin 4
Multiple Airlines Logo
4:41 pm - 9:20 am
DSM
-
CUN
16h 39m
1 stop
Multiple Airlines Logo
10:30 am - 9:27 pm
CUN
-
DSM
10h 57m
1 stop
$393Multiple Airlines
jeu., mai 28 - jeu., juin 4
Multiple Airlines Logo
4:41 pm - 2:07 pm
DSM
-
CUN
21h 26m
2 stops
Multiple Airlines Logo
10:30 am - 9:27 pm
CUN
-
DSM
10h 57m
1 stop
$403Multiple Airlines
mer., juin 10 - mer., juin 17
American Airlines Logo
5:30 am - 2:10 pm
DSM
-
CZM
9h 40m
1 stop
American Airlines Logo
3:12 pm - 9:11 am
CZM
-
DSM
16h 59m
1 stop
$510American Airlines
mar., juin 9 - mar., juin 16
American Airlines Logo
5:30 am - 2:11 pm
DSM
-
CZM
9h 41m
1 stop
American Airlines Logo
3:11 pm - 10:52 pm
CZM
-
DSM
6h 41m
1 stop
$560American Airlines
sam., août 8 - mar., août 11
United Airlines Logo
6:51 pm - 2:42 pm
DSM
-
CZM
20h 51m
2 stops
United Airlines Logo
3:52 pm - 10:26 pm
CZM
-
DSM
5h 34m
1 stop
$564United Airlines
dim., août 16 - jeu., août 27
United Airlines Logo
5:00 am - 12:48 pm
DSM
-
SJD
9h 48m
2 stops
United Airlines Logo
1:17 pm - 11:55 pm
SJD
-
DSM
8h 38m
1 stop
$592United Airlines
mar., sept. 29 - ven., oct. 2
Delta Logo
5:45 am - 11:10 am
DSM
-
SJD
7h 25m
1 stop
Delta Logo
6:04 am - 10:26 pm
SJD
-
DSM
14h 22m
2 stops
$616Delta
mar., sept. 29 - ven., oct. 2
Delta Logo
5:45 am - 11:10 am
DSM
-
SJD
7h 25m
1 stop
Delta Logo
12:15 pm - 10:26 pm
SJD
-
DSM
8h 11m
1 stop
$617Delta
dim., oct. 11 - ven., oct. 16
Aeromexico Logo
2:15 pm - 9:33 am
DSM
-
SJD
21h 18m
2 stops
Aeromexico Logo
6:04 am - 10:29 pm
SJD
-
DSM
14h 25m
2 stops
$637Aeromexico
mer., août 26 - dim., août 30
Aeromexico Logo
2:15 pm - 8:50 am
DSM
-
MTY
19h 35m
2 stops
Aeromexico Logo
9:09 pm - 5:42 pm
MTY
-
DSM
19h 33m
2 stops
$640Aeromexico
Booking Insights

KAYAK's insights & trends for Des Moines to Mexico flights

Get data-powered insights and trends into flights from Des Moines to Mexico to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Des Moines to Mexico?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Mexico, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Mexico is May, when tickets cost $192 (return) on average. On the other hand, the most expensive months are August and July, when the average cost of round-trip tickets is $366 and $364 respectively.

How far in advance should I book a flight from Des Moines to Mexico?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Des Moines to Mexico, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Des Moines to Mexico, you should book around 2 weeks before departure, which saves you about 21% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 21 weeks before departure.

Good to know

Low seasonAugust
Cheapest flight$187
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Des Moines to Guadalajara

FAQs - booking Mexico flights

  • How does KAYAK find such low prices on flights from Des Moines to Mexico?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Mexico.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Mexico?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to Mexico is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Mexico?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to Mexico with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Mexico?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to Mexico up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Des Moines to Mexico

 
Need help choosing which airline to fly with from Des Moines to Mexico? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4315 reviews
8.6Crew
8.0Comfort
7.5Entertainment
7.0Food
8.1Boarding
Airline reviews

The entire experience from boarding to landing was amazing! The crew were very friendly. Will definitely be back.

10.0 Excellentlarry, Apr 2026
LGB - PHX
Read more Southwest reviews

The entire experience from boarding to landing was amazing! The crew were very friendly. Will definitely be back.

no service at all due to turbulence. they should've at least given us snacks, there were only 10 people on the entire flight.

First time I've had to use the disabled accommodations. And I could not have had a better experience with Southwest, i was having trouble getting from one terminal to another due to my heart failure. And the next thing I know a Southwest agent had made sure. I had a wheelchair at all my flights. Can't thank them enough.

Delayed flight, lack of information, boarding process is a mess as is the carryon luggage causing issues when leaving the plane….just a poor experience.

Comfortable. Easy. No problems. Just wish they had gf options for snacks.

The crew was very kind and made going to Hawaii relaxing and fun to look forward to! Thank you Southwest for a pleasant flight!

This leg was much better, but we did have to have a 3 hour lay o er after coming from a very exhausting hiccup with our flight from BNA to Den

We waited in the airplane for over 45 min for a southwest employee to make the flight. This cause over half the plane to miss their connecting flight in Denver. When we confronted the desk upon arrival, they told us the only flight they had was the next day leaving at 8:50 pm!!! Or they offered to get us to Burbank or LA, but after that we were on our own to get back to Santa Barbara. I paid for a flight from sba to bna bna to sba. My re entry into mom mode has been 💯 rough because of southwest mistake with my flight. And now I’m leaving to Reno tomorrow for a vballl tournament and just discovered that my leg in Vegas has me and my 3 kids on a stand by flight even though I had booked these ticket last year November!! Do better southwest!

Southwest is kind of a slum airline. It’s gotten more expensive over the years for less and less service. I am a Southwest Chase Visa card holder and was forced to choose a seat in the 26th row in the middle seat. However my wife who is a rewards member but doesn’t hold a card or anything else, gets randomly assigned a normally paid seat in row 6! How does that work?

For the first time in a long time, the Wi-Fi actually worked the entire flight! The flight crew was amazing as usual.

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

Very easy to use and convenient, you can perform any action within the same portal

In a world of delays, Delta was on time both ways! Boarding was fast and efficient. Staff was friendly. AND wifi worked.

WiFi didn’t work. Flight delayed 3 hours Crew members were illiterate Seat lean back did not work.

Flight was delayed, we could have been notified earlier and in a consistent manner. App was not refreshing for another passenger to get the latest flight status. We could have stayed and waited at the hotel instead of waiting at the airport had we known the flight was going to delayed for more than 5 hours. The toilet is too tight, and needs to be cleaned more frequently (every hour). The entertainment screen froze, the touch screen not responding to touch. We were upgraded to comfort, it is more comfortable than regular economy seats.

Some crew were unfriendly or in some cases just straight up rude.

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

Was great in general, try to respect time and excuses when slight changes have been made, appreciated!

A long delay. Don't travel late in the day.

Super friendly with lots of drink options an entertainment. Friendly crew.

Standard flight with a drinks and a snack- overall very quick flight. The flight attendants were very strict, bordered on rude.

Outstanding service, efficient & friendly crew, flight was safe, comfortable & on time

United Airline crews were very friendly and very attentive. 12 hours flight was gone like in a shorter one.

Delayed - weather wasn't bad at either end. Also sat on tarmac in ORD.

Food was surprisingly delicious. Space in the seat is horrible when the seating front is reclined. Movie offerings were terrible. Crew was friendly and helpful.

All went very well. We used the AIFI Airport, such a lovely facility. Definitely needs better transportation options to get there.

Both ground crew and flight crew were rude, and did not provide any level of service. They made it very difficult as we were traveling with a passenger the required assistance.

From the check-in, to the flight, and arriving, everything went very smoothly. Unfortunately, when I received my baggage it was severely damaged. I have a hard shelled suitcase and it was completely smashed it. I’m not sure how this could happened but I am extremely disappointed that my belongings were damaged beyond repair and continued use.

Really nice, all good, nice crew and all on time

Unfortunately I had an awful boarding experience. Our first flight with Aeromexico was fine and landed on time however it couldn’t find a gate and we were late which made us lose our connecting flight with Aeromexico. The staff handled it horribly when we explained our situation and would not led us board when we missed the boarding time by a couple minutes. The staff were extremely rude and did not attempt to even help us. Because of this incident, my husband and I missed a full day of work which negatively impacted our salary which we need. Please compensate us for the work that we missed.

It was OK. The flight is pretty long for the airlines to only offer a simple sandwich on business class. The entertainment is similar to that on other Skyteam members. Ultimately the airline lost my bag and didn’t deliver it to me until the next day after a lengthy lost baggage report.

Good, the flight from Miami to Mexico City was better than Mexico City to Miami

Aeroméxico cancelled my ticket without advice AND It make a last minute mess in my intinerary, no solving my situation, bad advice and bad customer service

Flight was on time, good service, but there was no free WiFi, even for first class passengers

It was good in general. The Crew during the flight were very nice at all times.

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

I would like a refund for the extra cost the seat I paid for. An oversized person sat next to me and I couldn’t fit on my seat and had to move to another seat.

Boarding gate at LAX was too crowded—two gates next to one another

The flight was delayed about an hour for a maintenance specialist to approve the maintenance repair

This flight was delayed but it worked in my favor because my Atlanta to Dallas flight was delayed.

This was a hard flight. 3 delays out of OKC (1 on the Tarmac). Delay in Atlanta coming to Dallas. total travel time was the equivalent of driving from OKC to Atlanta.

Like: flights are on time, good boarding process Can improve: planes are old, improve entertainment and make space more comfortable

Had to wait for a gate for a long time, then waited on the run way for a long time before leaving. The actual flights part was good.

The airplane was an old model, the overhead didn’t have enough room for people’s items and made boarding and boarding disappointing and stressful. Crew allowed passengers to bring more than the permitted baggage sizes.

Flying in the United States with the major airlines has become so underwhelming. A 2-3hr flight in most other parts of the world with the major carriers of the area comes with newer, CLEANER aircraft and significantly better in flight service in terms of both staff attitude and a actual meal service.

Everything you need to know for your flight from Des Moines to Mexico

Information on your arrival and departure airports