$80 Find Cheap Flights from Des Moines to Ohio

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Ohio departing on 4/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Ohio

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Ohio, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Ohio, as well as popular online travel agencies
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Cheap Flights from Des Moines to Ohio

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Cleveland
Cleveland1 stop$226
Cincinnati
Cincinnati1 stop$226
Dayton
Dayton1 stop$269
Cleveland
Cleveland1 stop$226
Cincinnati
Cincinnati1 stop$226
Dayton
Dayton1 stop$269

Book Cheap Des Moines to Ohio Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Ohio that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Ohio

Tue, Mar 10 - Sat, Mar 14
Frontier Logo
11:00 am - 12:41 am
DSM
-
CVG
12h 41m
1 stop
Frontier Logo
8:20 am - 7:16 pm
CVG
-
DSM
11h 56m
1 stop
$226Frontier
Tue, Mar 10 - Sat, Mar 14
Frontier Logo
11:00 am - 1:13 am
DSM
-
CLE
13h 13m
1 stop
Frontier Logo
4:31 pm - 9:45 am
CLE
-
DSM
18h 14m
1 stop
$226Frontier
Sat, Apr 11 - Sat, Apr 18
American Airlines Logo
6:00 am - 5:45 pm
DSM
-
CMH
10h 45m
1 stop
American Airlines Logo
6:05 am - 1:46 pm
CMH
-
DSM
8h 41m
1 stop
$261American Airlines
Sun, Apr 12 - Thu, Apr 16
American Airlines Logo
11:09 am - 11:22 pm
DSM
-
CMH
11h 13m
1 stop
American Airlines Logo
6:05 am - 1:46 pm
CMH
-
DSM
8h 41m
1 stop
$263American Airlines
Sat, Apr 11 - Thu, Apr 16
United Airlines Logo
1:10 pm - 11:40 pm
DSM
-
CMH
9h 30m
2 stops
United Airlines Logo
5:40 am - 10:44 am
CMH
-
DSM
6h 04m
1 stop
$268United Airlines
Tue, Apr 28 - Tue, Apr 28
Delta Logo
6:10 am - 11:39 am
DSM
-
CVG
4h 29m
1 stop
Delta Logo
4:22 pm - 10:34 pm
CVG
-
DSM
7h 12m
1 stop
$271Delta
Tue, Apr 28 - Tue, Apr 28
Southwest Logo
5:30 am - 12:40 pm
DSM
-
CVG
6h 10m
2 stops
Southwest Logo
7:35 pm - 10:10 pm
CVG
-
DSM
3h 35m
1 stop
$277Southwest
Tue, Apr 28 - Tue, Apr 28
Southwest Logo
5:30 am - 12:40 pm
DSM
-
CVG
6h 10m
2 stops
Southwest Logo
3:50 pm - 10:10 pm
CVG
-
DSM
7h 20m
2 stops
$283Southwest
Mon, May 11 - Wed, May 13
United Airlines Logo
5:00 am - 1:11 pm
DSM
-
PIT
7h 11m
1 stop
United Airlines Logo
10:55 am - 2:24 pm
PIT
-
DSM
4h 29m
1 stop
$287United Airlines
Sat, Mar 21 - Wed, Mar 25
Delta Logo
4:25 pm - 11:57 pm
DSM
-
CMH
6h 32m
1 stop
Delta Logo
10:55 am - 3:42 pm
CMH
-
DSM
5h 47m
1 stop
$291Delta
Booking Insights

KAYAK's insights & trends for Des Moines to Ohio flights

Get data-powered insights and trends into flights from Des Moines to Ohio to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to Ohio?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to Ohio were found on American Airlines ($261) and United Airlines ($268).

Good to know

Low seasonJanuary
Cheapest flight$80
Best time to beat the crowds but there is an average 18% increase in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Des Moines to Detroit

FAQs - booking Ohio flights

  • How does KAYAK find such low prices on flights from Des Moines to Ohio?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Ohio.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Ohio?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to Ohio is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Ohio?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to Ohio with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Ohio?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to Ohio up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to Ohio

  • Looking for a cheap flight? 25% of our users found tickets from Des Moines to the following destinations at these prices or less: Detroit $213 one-way - $418 round-trip

Reviews of the top 4 airlines serving from Des Moines to Ohio

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Ohio. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Ohio? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4301 reviews
7.5Entertainment
7.0Food
8.6Crew
8.1Boarding
8.0Comfort
Airline reviews

It was canceled. Supposedly weather. But there was no snow in Baltimore. At least we found out before driving to airport

2.0 MediocreAnonymous, Feb 2026
BWI - PBI
Read more Southwest reviews

It was canceled. Supposedly weather. But there was no snow in Baltimore. At least we found out before driving to airport

I have not flown Southwest in awhile and had a very pleasant experience. From ticketing to boarding to the flight. The flight left on time and landed ahead of schedule. It won't be so long next time!!

The Southwest experience has definitely taken a dive from its early days. You can no longer deferentiate from other airlines. Air travel is too expensive. Southwest is no longer budget friendly. They have lost me as a loyal customer.

Flight was hours late, unable to sit next to spouse, I have had so much better experiences. Substantially better, only saving grace was that it was a short flight.

An entire day of delays. Cost lots of money. Meals and a hotel.

The WiFi and crew on the plane were good, however, the boarding experience was awful. I paid for the Choice Preferred and was boarded in group 5 so all overhead storage was full. They found room for our luggage, but further back making getting off the plane a nightmare. Also, we were in row 6 and the seats were extremely uncomfortable. Both my daughter and I had no leg room and couldn’t wait to get off the plane.

The charges were ridiculous for an hour flight and the turbulence was very scary.

Still need to work out the kinks on the new assigned seating boarding process. Otherwise, a very good flight.

WiFi did not work. Boarding with the new seating assignments took too long. The temperature in the terminal was obnoxious. +/- 80°

The seats are now more narrow. I paid for front row the seats in the front are even more narrow than before.

Everything was good except wifi and a leaking drink chiller. The floor was all wet and my bag was soaked. Did not notice until debarking. Have not heard back from Delta. Even though this was leg one of an international flight in first class, they denied access to their Sky Club - very disappointing!

The staff was fine. The plane was extremely tight, and I paid for the wifi and it did not work at all. I was actually going to ask for a refund.

two hour delay and the Delta representative on the PA system was unable to understand

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

2+hrs delay without any reason provided and a cramped flight

We waited an hour on the runway to get a gate in Orlando

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

Flight was delayed due to crew being not on time

Flight crew issues delayed my flight by 2 1/2 hours. Causing me to miss my connection.

The staff on board and gate was nice - a welcome change from the usual. We also arrived early, which was a great benefit, given that it takes 30 minutes plus to get bags at SRQ.

Flight delayed for more than 16 hrs and no effort was spent to provide an alternate

We got delayed three hours and nobody thought to have the bathroom fixed while we were sitting waiting to board? took a full hour to have maintenance come and check it off. Had to shut the bathroom down twice so that the pilots could go to the bathroom. Everyone missed their connections.

Flight left on time and we arrived 25 minutes early! There was a gate available when we arrived so early on a busy Sunday afternoon! Flight attendants came around twice with the drinks cart.

Wonderful. Quick boarding. Early departure and we arrived 30 minutes early at our destination. Unfortunately, when you arrive early, there is still a departing aircraft at our gate. We had to park for 30 minutes until the gate was clear. So our early arrival was not really early at the gate. Otherwise it was a quick and smooth flight. Appreciated the efficiency.

Everything was great except for the boarding process. Everyone is lining up all at the same time and it’s hard to tell between the groups as they are way too large.

Women boarding passengers at the gate was absolutely rude and disrespectful of passengers. The flight attendant was absolutely delightful! Smiling and connected with the passengers. So happy. The seats are cramped and uncomfortable but I guess that’s just the way it is Communication regarding flight was excellent

Overall we had a good experience during our flight from San Francisco to Houston.

Airport terminal was outdated, flight was on a small jet with no wifi

We were delayed for about an hour from taking off due to traffic control procedures at the destination airport. But once in the air, the flight went well. The crew members were great and provided cabin service despite moderate turbulence during much of the flight.

it was a very short flight so my expectations were low.

It's very confusing because Kayak has it as American Airlines, but it was Hawaiian Airlines, but operated by Alaska Airlines. I had to go to the airport for my boarding pass because American said I didn't have any trips.

Smooth flight. From the early boarding and all were on board before departure time and arrived early in ONT. Great crew. Thank you!!!!

Small plane, poor meal choices for first class, bad terminal and boarding experience at LAX

Lack of gluten free options in food service. I have Celiac disease and it appears you no longer offer special meals for people with dietary restrictions. I am a frequent flyer traveling into and out of Omaha airport. I have noticed over the course of several months that although our flight typically arrives ahead of schedule (awesome job AA!) - we typically sit on the runway for several minutes waiting for the ground crew to get in place. Not sure if it is a ground crew issue or a gate availability issue (due to construction at this airport). Seems to be more of a ground crew being on time issue.

Arrived early picked up my bag in a few minutes- great trip - thank you

Flight boarded, departed and landed on time. Excellent service from flight attendant in FIRST

Boarding is always an ordeal. Less dogs on flights. I am highly allergic to dogs and cats. Why are there so many animals these days?

Flight to Tampa was delayed taking off due to plane arriving late but no other issues

There was a delay with the plan which cause the flight to leave later and once arrived in Chicago there was another delay and some passengers missed their connecting flights

Massimo, flight attendant was very authentic, attentive - wonderful. Food/wrap was just okay.

Everything you need to know for your flight from Des Moines to Ohio

Information on your arrival and departure airports