$106 Find Cheap Flights from Des Moines to Ohio

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Ohio departing on 6/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Ohio

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Ohio, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Ohio, as well as popular online travel agencies
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Cheap Flights from Des Moines to Ohio

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Cleveland
Cleveland1 stop$319
Cincinnati
Cincinnati1 stop$284
Dayton
Dayton1 stop$309
Cleveland
Cleveland1 stop$319
Cincinnati
Cincinnati1 stop$284
Dayton
Dayton1 stop$309

Book Cheap Des Moines to Ohio Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Ohio that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Ohio

Wed, Jul 8 - Wed, Jul 15
Frontier Logo
2:19 pm - 11:59 pm
DSM
-
DTW
8h 40m
1 stop
Frontier Logo
7:40 am - 1:34 pm
DTW
-
DSM
6h 54m
1 stop
$230Frontier
Sat, Jul 4 - Sat, Jul 11
Allegiant Air Logo
8:00 am - 10:48 pm
DSM
-
CVG
13h 48m
1 stop
Allegiant Air Logo
5:45 pm - 8:33 am
CVG
-
DSM
15h 48m
1 stop
$284Allegiant Air
Wed, Jun 17 - Wed, Jun 24
American Airlines Logo
7:09 pm - 12:18 am
DSM
-
DAY
4h 09m
1 stop
American Airlines Logo
6:31 am - 12:52 pm
DAY
-
DSM
7h 21m
1 stop
$309American Airlines
Wed, Jun 24 - Wed, Jul 22
Delta Logo
11:28 am - 5:21 pm
DSM
-
CMH
4h 53m
1 stop
Delta Logo
5:16 pm - 10:29 pm
CMH
-
DSM
6h 13m
1 stop
$319Delta
Tue, Jun 23 - Tue, Jun 30
Southwest Logo
5:20 am - 10:05 am
DSM
-
CLE
3h 45m
1 stop
Southwest Logo
8:25 am - 11:30 am
CLE
-
DSM
4h 05m
1 stop
$319Southwest
Tue, Jul 7 - Wed, Jul 8
Southwest Logo
5:20 am - 1:20 pm
DSM
-
CMH
7h 00m
2 stops
Southwest Logo
7:50 pm - 10:50 pm
CMH
-
DSM
4h 00m
1 stop
$324Southwest
Thu, Oct 15 - Wed, Oct 21
American Airlines Logo
6:00 am - 12:05 pm
DSM
-
PIT
5h 05m
1 stop
American Airlines Logo
6:45 pm - 11:55 pm
PIT
-
DSM
6h 10m
1 stop
$337American Airlines
Wed, Jun 10 - Sun, Jun 14
United Airlines Logo
11:26 am - 5:22 pm
DSM
-
CAK
4h 56m
1 stop
United Airlines Logo
6:06 pm - 10:51 pm
CAK
-
DSM
5h 45m
1 stop
$339United Airlines
Wed, Jul 22 - Sun, Jul 26
Delta Logo
6:00 am - 1:27 pm
DSM
-
CMH
6h 27m
1 stop
Delta Logo
7:00 am - 10:13 am
CMH
-
DSM
4h 13m
1 stop
$353Delta
Wed, Jul 1 - Thu, Jul 2
United Airlines Logo
6:00 am - 2:03 pm
DSM
-
PIT
7h 03m
2 stops
United Airlines Logo
7:40 pm - 10:56 pm
PIT
-
DSM
4h 16m
1 stop
$358United Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Ohio flights

Get data-powered insights and trends into flights from Des Moines to Ohio to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Des Moines to Ohio?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to Ohio departing in June.

What is the cheapest month to fly from Des Moines to Ohio?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Ohio, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Ohio is July, when tickets cost $108 (return) on average. On the other hand, the most expensive months are January and April, when the average cost of round-trip tickets is $309 and $288 respectively.

Good to know

Low seasonJanuary
Cheapest flight$106
Best time to beat the crowds but there is an average 11% increase in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Des Moines to Pittsburgh

FAQs - booking Ohio flights

  • How does KAYAK find such low prices on flights from Des Moines to Ohio?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Ohio.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Ohio?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to Ohio is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Ohio?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to Ohio with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Ohio?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to Ohio up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to Ohio

  • Looking for a cheap flight? 25% of our users found tickets from Des Moines to the following destinations at these prices or less: Detroit $193 one-way - $373 round-trip

Reviews of the top 4 airlines serving from Des Moines to Ohio

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Ohio. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Ohio? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4264 reviews
8.1Boarding
8.0Comfort
8.6Crew
7.5Entertainment
7.0Food
Airline reviews

The first time I flew in the extra legroom section. It was difficult to notice a difference. I had bad luck with my neighbors. The crew was okay. Southwest has reduced the live TV options.

4.0 OkayAnonymous, May 2026
MDW - LAX
Read more Southwest reviews

The first time I flew in the extra legroom section. It was difficult to notice a difference. I had bad luck with my neighbors. The crew was okay. Southwest has reduced the live TV options.

The flight was smooth. The Southwest experience has degraded overall, but this one was okay.

No gluten free snacks. Seats felt worn or bare bones even though it was a new 737 MAX 8.

One major problem that was very unprofessional and uncalled for. Plane landed and we had to wait 20 minutes to get off the plane since they were waiting for someone to come to the gate to drive the jetway. Southwest couldn't have someone available and waiting for the plane to land? Is there only one person in Hobby airport who knows to drive the jetway? Was he at lunch? In the bar? Uncomfortable and uncalled for!

The checking experience in Orlando was terrible, almost missed the flight. Too many travelers and Southwest completely understaffed.

I'm glad it wasn't only 75% full because I could get a good seat

if I was good. Not happy that I have to pay extra money to get the seat I need for lake room, but I guess that’s a sign of the times.

Seats were very comfortable. They tilted back. Drinks and snacks were free and served 3 times. Attendants were awesome.

Plane was clean and comfortable. Flight attendants and gate staff were professional, friendly and efficient. Boarding and deplaning were orderly and efficient. All in all, the typical excellent Southwest experience.

Truly terrible. Will never willingly fly southwest again. Seats are worse than before they switched to assigned seating. One flight attendant was the opposite of helpful (rude, unhelpful, dismissive, and as my stranger seatmate said unprompted: a total prick). This caused me, 15 minutes into the flight, to book an alternate return flight home on a competing airline (first class 1.2k purchase instead of my existing planned flight) just so I would not have to ever be on that aircraft, with that terrible service person, with those horrific seats ever again.

No service flight that took 5 hrs and a stop at an unscheduled airport. Crew and pilots did their jobs

Clean planes and not take my comfort class seat away.

Weather caused a long delay, but the efficiency and updates from the pilot were helpful. We were able to make our connection fortunately.

Planes were clean, no water or snacks on either flight.

Free & relatively fast Wi-Fi. Would've liked a wider drink selection.

I continue to be satisfied with Delta’s excellent service out of LGA. The digit id works well and gets me through security in no time. Whenever possible, I choose Delta.

Was revoked with Jet Blue due to delay from Kenya Air

Enjoyed it very much. Especially liked the free WiFi that Delta offers.

Smooth flight. Left on time, and got in 15 minutes early. Onboard video was great

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

Flight was delayed but more than 90 minutes. This caused me to miss my available windows for pick-up by a friend. I had to pay $125 for an uber back home from the airport which was an added expense that I had not budgeted for my trip. Staff was friendly.

Seat pitch is horrible especially on the 15 hour flight. Gate crew at SFO was Outstanding. The flight crew was also great.

Had a one hour delay due to mechanical issue. I didn’t think I’d be able to make my connecting flight, but they waited for me and greeted me when I arrived to help things run smooth.

6 1/2 hours from Tampa to SFO on a Boeing 737. Cramped. No Service. No real food. One pass for coffee at the beginning and a second pass THREE hours later. And check-in in Tampa was nasty even by United standards. And I am at almost TWO million miles on United. It's a non-stop. But terrible service.

MY FAMILY'S LUGGAGE WAS LOST FROM ROME TO BARI. I WAS THE ONLY ONE THAT RECEIVED MY LUGGAGE FROM ROME TO BARI. AFTER DEPLANING IN BARI, WE WASTED A LOT OF TIME AT BAG CLAIMS LOST AND FOUND REPORTING THE CLAIM AND PLEADING FOR THE BAGS TO BE DELIVERED THE NEXT DAY. WE WERE TOLD THAT IT TAKES 3 DAYS MINIMUM TO DELIVER. MY DAUGHTER AND MY GIRLFRIEND NEEDED THEIR PERSONAL THINGS AND WE WERE STAYING 3 HOURS AWAY FROM THE BARI AIRPORT. WE HAD TO DRIVE 3 HOURS TO THE AIRPORT TO COLLECT OUR LOST LUGGAGE THE NEXT DAY. WE ARE NOT HAPPY WITH THE EXPERIENCE

We had a delay, but thankfully I made it to my connection. Overall it went smooth

The flight had a delay but I made it to my connection. Flight was smooth overall

As I wrote earlier, poor planning and/or communication. At least twice, we were told that we would be boarding in less than ten minutes, only to have the flight again delayed at least another hour.

This flight is a quick way to get to Chicago, but a bit expensive.

Our flight to Rome, Italy was cancelled the day of and we were never informed. We only found out because I was trying to get into my husbands account and called to get his account number. Had to pay more for worse seating on another airline.

Movies on my phone are great. It would be nice to have a gluten free snack option.

It was what i expected. I like the movies you can access from your phone. It would be nice if there was a gluten free snack offered. But I did bring my own snack knowing there would not be a gluten free option

The flight was peaceful, just s slight turbulence, pilots and crews were all nice and made a great job! Arrived safely in the Philippines. Thank you ya’ll!

Ontario airport boarding was very easy to park and access, is clean and TSA took 10 minutes total. Check-in was a breeze and cruise was very nice.

American Airlines II: Delay Boogaloo. Multiple gate changes, delays, boarded and then MORE delays. I hate to say this won’t matter, but posting stuff about major corporations in 2026 is a post-modern “scream into the void.” Was multiple hours late coming home, so there you go.

Awful, tons of delays, I got into Chicago multiple hours late meaning I hit the very traffic I tried so desperately to avoid. Just empty apologies from American Airlines text alerts. Trash behavior from a trash airline.

The flight attendants were very friendly, efficient, and helpful. The plane was ahead of schedule, and it all went very smoothly. Thank you.

They lost my baggage and I am still struggling to the information and update

We got delayed getting out of DFW for broken overhead bins. Once the flight got underway the captain kept the seatbelt sign lit the entire flight despite little perceptible turbulence, preventing use of the rest rooms and any sort of refreshment service in the main cabin.

Flight delays for communication overall not a good experience uncomfortable on the plane. Person in front of me reclined his seat, putting them inches from my lap.

Everything you need to know for your flight from Des Moines to Ohio

Information on your arrival and departure airports